MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Hyperprolactinemia

(UMLS:C0020514)

Definition:: Increased levels of PROLACTIN in the BLOOD, which may be associated with AMENORRHEA and GALACTORRHEA. Relatively common etiologies include PROLACTINOMA, medication effect, KIDNEY FAILURE, granulomatous diseases of the PITUITARY GLAND, and disorders which interfere with the hypothalamic inhibition of prolactin release. Ectopic (non-pituitary) production of prolactin may also occur. (From Joynt, Clinical Neurology, 1992, Ch36, pp77-8)
UMLS ID:: C0020514
MeSH ID:: D006966

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.140.617.738.250.450

Classification 2:

Name:

Endocrine System Diseases
MeSH Tree Number(s):: C19.700.355.600

Synonym(s)

Hyperprolactinemia

HYPERPROLACTINAEMIA

HYPERPROLACTINEMIA

Hyperprolactinaemia

Hyperprolactinaemia, NOS

Hyperprolactinemia, NOS

hyperprolactinaemia

hyperprolactinemia

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Alprazolam	8803653	CTD
2	Amisulpride	View details 12106810 12144950 14509051 14966260 15225684 15467977 15665803 16938372 16942633 17414262 17606473 18063941 18585544 18950385 18950388 19265646 20732372	CTD
3	Aripiprazole	View details 8613910 16055781 16965214 17728426 17873694 19038534 19653986 19744015 20732372 20814333 21179629	CTD
4	Azathioprine	12488716	CTD
5	Bromocriptine	View details 1359137 1656408 1681002 3117594 3745407 4047382 6488683 7293665 8959084 9334596 10819748 11194712 12106810 14750048 16209236 18480682 19968833 24187407 29551354	CTD
6	Cabergoline	View details 3745407 11194712 11838826 15003071 17566512 19336508 24187407	CTD
7	Chlorpromazine	564936 718334	CTD
8	Cimetidine	9037573	CTD
9	Clomiphene	3346359	CTD
10	Clonidine	16401171	CTD
11	Clozapine	564936 15243877	CTD
12	Cocaine	2257288 2584360	CTD
13	Cyclosporine	11924803	CTD
14	Cytarabine	8312290	CTD
15	Danazol	4087275	CTD
16	Diethylstilbestrol	1678068 4092719 9500197	CTD
17	Domperidone	View details 1823276 6736848 7133322 9037573 10568223 10681812 16960712 20516720	CTD
18	Estradiol	View details 2105248 2446353 2656304 3346359 3964786 7962471 9500197 9819799 10569801	CTD
19	Famotidine	8104296	CTD
20	Fenfluramine	1678730	CTD
21	Fluoxetine	9098464 16848655 18585544	CTD
22	Fluphenazine	9192542	CTD
23	Haloperidol	View details 564936 1681002 3019639 3158510 3748306 3883215 3906589 7018927 8613910 9128918 9192542 9572212 10661492 11048906 15289996 15638391 16282852	CTD
24	LHRH, N-acetyl-(4-chlorophenylalanyl)(1)-(4-chlorophenylalanyl)(2)-tryptophyl(3)-arginyl(6)-alanine(10)-	2656304 3906589	CTD
25	Labetalol	7105431	CTD
26	Lisuride	386688 6492995	CTD
27	Methadone	21094671	CTD
28	Methyldopa	1681002 7265421	CTD
29	Methylprednisolone	11924803	CTD
30	Metoclopramide	View details 564936 1605398 2635674 7270091 8191163 9352036 12056626 14655152 16529173 16584088 16815880 17187127 18978642 19304288 19838586	CTD
31	Mifepristone	2159045 7962471	CTD
32	Molindone	26327279	CTD
33	Olanzapine	16085789 20176014	CTD
34	Paliperidone Palmitate	17502783	CTD
35	Perphenazine	6770916 7262630 9766782	CTD
36	Pimozide	9131265	CTD
37	Progesterone	View details 2105248 2656304 3346359 3964786 7962471	CTD
38	Ranitidine	7878608 9037573	CTD
39	Reserpine	6492995 8613910 9819799	CTD
40	Risperidone	View details 9766782 10084644 11155212 11194712 11838821 11838826 11927762 12019665 12450970 12549948 12625994 12650681 12860772 14509051 14624190 14750048 14870961 15003071 15286066 15289996 15465997 15641867 15960571 15985938 16055781 16085789 16379508 16633146 16716128 16889453 16889455 16965214 17017838 17069546 17187006 17196055 17502783 17519641 17566512 17606473 17873693 18063941 18480682 18585544 18848860 19038534 19153927 19265646 19339912 19473900 19653986 19744015 19809337 20035598 20176014 20305606 20331935 20595935 20732372 20814333 21179629	CTD
41	Sulpiride	View details 475305 564936 956353 2204052 2943108 2948424 2954994 3137082 3891423 4001434 6300590 6643949 6777091 7243090 18082301 18162529 18848860 18978642 20732372 29551354	CTD
42	Thioridazine	View details 564936 4047382 4065553 9192542	CTD
43	Triptorelin Pamoate	2954994 3158510	CTD
44	Venlafaxine Hydrochloride	19303910	CTD
45	Verapamil	View details 6682619 8845563 8977754 16209236	CTD
46	Yohimbine	1678730	CTD
47	bisphenol A	11108262	CTD
48	bromerguride	6492995	CTD
49	carbidopa, levodopa drug combination	7105431	CTD
50	carmoxirole	12106810	CTD
51	haloperidol decanoate	17873694	CTD
52	mesulergine	6488683	CTD
53	perphenazine GABA ester	20921890	CTD
54	quinagolide	12058109	CTD
55	talipexole	8613910	CTD
56	ziprasidone	15243877 15465997 18950388	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Acromegaly	38.8%
2	Empty Sella Syndrome	34%
3	Hypopituitarism	34%
4	Hypophysitis	34%
5	Pituitary Apoplexy	25.3%
6	Pituitary Adenoma	20.4%
7	Pituitary Neoplasms	20.4%
8	Gigantism	18.5%
9	Akinetic Mutism	17.2%
10	Anoxic Encephalopathy	17.2%
11	Basal Ganglia Diseases	17.2%
12	Brain Damage, Chronic	17.2%
13	Cerebellar Diseases	17.2%
14	Encephalitis	17.2%
15	Encephalomalacia	17.2%
16	Epilepsy	17.2%
17	Hydrocephalus	17.2%
18	Congenital Hydrocephalus	17.2%
19	Thalamic Diseases	17.2%
20	Intracranial Hypertension	17.2%
21	Aura	17.2%
22	Leukoencephalopathy	17.2%
23	Neuroaxonal Dystrophies	17.2%
24	Headache Disorders	17.2%
25	Intracranial Hypotension	17.2%
26	Brain Edema	17.2%
27	Brain Hypoxia	17.2%
28	Aqueductal Stenosis	17.2%
29	Encephalomyelitis	16.3%
30	Subdural Effusion	15.9%
31	Prolactinoma	14.6%
32	Growth Hormone-Secreting Pituitary Adenoma	14.6%
33	Meningitis	14.2%
34	Movement Disorders	14.2%
35	Pachymeningitis	14.2%
36	Spinal Cord Diseases	14.2%
37	Meningoencephalitis	14.1%
38	Brain Diseases, Metabolic	13.2%
39	Cerebrovascular Disorders	13.2%
40	Cerebrovascular Insufficiency	13.2%
41	Dementia	13.2%
42	Parkinsonian Disorders	12.6%
43	Nelson Syndrome	12.6%
44	Pneumocephalus	12.4%
45	Brain Abscess	12.4%
46	Multiple System Atrophy	12.2%
47	Ocular Motility Disorders	12%
48	Cyclophoria	12%
49	Dandy-Walker Syndrome	12%
50	Diabetes Insipidus	11.9%
51	Brain Injuries	11.9%
52	Brain Neoplasms	11.8%
53	Adrenal Gland Diseases	11.7%
54	Gonadal Disorders	11.7%
55	Parathyroid Diseases	11.7%
56	Thyroid Diseases	11.7%
57	Basal Ganglia Cerebrovascular Disease	11.4%
58	Posterior Leukoencephalopathy Syndrome	11.3%
59	Posterior reversible encephalopathy syndrome	11.3%
60	Central Nervous System Infection	11.2%
61	Myelitis	11.1%
62	Marchiafava-Bignami Disease	10.8%
63	Dementia, Vascular	10.6%
64	Brain Death	10.6%
65	Lewy Body Disease	10.3%
66	Meige Syndrome	10.1%
67	Cerebral Ventriculitis	10.1%
68	Epilepsy, Post-Traumatic	10.1%
69	Cranial nerve diseases	9.6%
70	Demyelinating Diseases	9.6%
71	Demyelination	9.6%
72	Neuromuscular Diseases	9.6%
73	Chronobiology Disorders	9.6%
74	Leukomalacia, Periventricular	9.5%
75	Cerebral Palsy	9.4%
76	Epilepsies, Partial	9.4%
77	Epilepsy, Generalized	9.4%
78	Pseudotumor Cerebri	9.4%
79	Hypertensive Encephalopathy	9.4%
80	Simple Partial Seizures	9.4%
81	Epilepsy, Reflex	9.4%
82	Headache Disorders, Primary	9.4%
83	Headache Disorders, Secondary	9.4%
84	Medication overuse headache	9.4%
85	Epidural Abscess	9.4%
86	Amblyopia	9.3%
87	Prion Diseases	9.2%
88	Vascular Headaches	9.1%
89	Hypoxia-Ischemia, Brain	9%
90	Bone Diseases, Endocrine	8.8%
91	Endocrine Gland Neoplasms	8.8%
92	Parkinson Disease	8.7%
93	Diabetes Mellitus	8.6%
94	Neuroleptic Malignant Syndrome	8.6%
95	Myelinolysis, Central Pontine	8.6%
96	Stiff-Person Syndrome	8.6%
97	Myoclonic Epilepsy	8.4%
98	Epilepsy, Temporal Lobe	8.4%
99	Epilepsy, Rolandic	8.4%
100	Benign Rolandic Epilepsy	8.4%
101	Creutzfeldt-Jakob disease	8.1%
102	Adrenal Gland Neoplasms	8.1%
103	Dystonia Musculorum Deformans	8%
104	Huntington Disease	8%
105	Cerebellar Neoplasms	7.9%
106	Spinal Cord Injuries	7.7%
107	Amnesia, Transient Global	7.6%
108	Trauma, Nervous System	7.5%
109	Spinal Muscular Atrophy	7.4%
110	Progressive Muscular Atrophy	7.4%
111	Arachnoiditis	7.4%
112	Aseptic Meningitis	7.4%
113	Syringomyelia	7.4%
114	Essential Tremor	7.4%
115	Familial Tremor	7.4%
116	Pneumorrhachis	7.4%
117	Writer's Cramp	7.4%
118	Asterixis	7.3%
119	Ballismus	7.3%
120	Progressive supranuclear palsy	7.3%
121	Subacute Combined Degeneration	7.3%
122	Nervous System Neoplasms	7.3%
123	Neurologic Manifestations	7.3%
124	Neurotoxicity Syndromes	7.3%
125	Motor Neuron Disease	7.2%
126	Presenile dementia	7.2%
127	Senile dementia	7.2%
128	Carotid Artery Diseases	7.1%
129	Brain Ischemia	7.1%
130	Cerebrovascular accident	7.1%
131	Kluver-Bucy Syndrome	7.1%
132	Vasospasm, Intracranial	7.1%
133	Intracranial Arterial Diseases	7.1%
134	Dwarfism	7%
135	Meningitis, Bacterial	6.9%
136	Meningitis, Fungal	6.9%
137	Limbic Encephalitis	6.9%
138	Parathyroid Neoplasms	6.8%
139	Thyroid Neoplasm	6.8%
140	Thyroid carcinoma	6.8%
141	Striatonigral Degeneration	6.7%
142	Adrenal Cortex Diseases	6.7%
143	Euthyroid Sick Syndromes	6.7%
144	Goiter	6.7%
145	Hyperparathyroidism	6.7%
146	Hyperthyroidism	6.7%
147	Hyperthyroxinemia	6.7%
148	Hypogonadism	6.7%
149	Hypoparathyroidism	6.7%
150	Hypothyroidism	6.7%
151	Delayed Puberty	6.7%
152	Precocious Puberty	6.7%
153	Thyroiditis	6.7%
154	Hypogonadotropic hypogonadism	6.7%
155	Testotoxicosis	6.7%
156	Secondary hypothyroidism	6.7%
157	Primary Hyperthyroidism	6.7%
158	Primary Hypothyroidism	6.7%
159	Brain Injuries, Diffuse	6.5%
160	Traumatic Brain Injury	6.5%
161	Cerebellar Ataxia	6.4%
162	Supratentorial Neoplasms	6.4%
163	Poliomyelitis	6.4%
164	Chronic Fatigue Syndrome	6.4%
165	Amyotrophic Lateral Sclerosis	6.3%
166	Leukoencephalopathy, Progressive Multifocal	6.3%
167	Vasculitis, Central Nervous System	6.2%
168	Persistent Vegetative State	6.1%
169	Paraneoplastic Cerebellar Degeneration	6%
170	Sleep Wake Disorders	5.9%
171	Spinal Cord Neoplasms	5.9%
172	Shy-Drager Syndrome	5.8%
173	Hepatolenticular Degeneration	5.8%
174	Reye Syndrome	5.7%
175	Intracranial Embolism and Thrombosis	5.7%
176	Hepatic Encephalopathy	5.7%
177	Restless Legs Syndrome	5.7%
178	Central Nervous System Fungal Infections	5.6%
179	Conus Medullaris Syndrome	5.6%
180	Spinal Cord Vascular Diseases	5.6%
181	Post-Traumatic Headache	5.6%
182	Tension Headache	5.6%
183	Epilepsy, Complex Partial	5.6%
184	Migraine Disorders	5.6%
185	Abdominal Migraine	5.6%
186	Status Migrainosus	5.6%
187	Cervicogenic Headache	5.6%
188	Brain Infarction	5.6%
189	Lupus Vasculitis, Central Nervous System	5.6%
190	Juvenile Myoclonic Epilepsy	5.6%
191	Basal Ganglia Hemorrhage	5.6%
192	Myoclonic Epilepsies, Progressive	5.6%
193	MPTP Poisoning	5.5%
194	Polyradiculoneuropathy	5.5%
195	Polyradiculoneuritis	5.5%
196	Autonomic Dysreflexia	5.4%
197	Complex Regional Pain Syndromes	5.4%
198	Ophthalmoplegic Migraine	5.3%
199	Toxoplasmosis, Cerebral	5.3%
200	Encephalomyelitis, Acute Disseminated	5.3%
201	Brain Hemorrhage, Traumatic	5.3%
202	Akathisia, Drug-Induced	5.3%
203	Carotid Artery Injuries	5.2%
204	Diabetic Neuropathies	5.1%
205	Diabetic Amyotrophy	5.1%
206	Diabetic Autonomic Neuropathy	5.1%
207	Testicular Diseases	5.1%
208	Leukoencephalitis, Acute Hemorrhagic	5.1%
209	Ovarian Diseases	5%
210	Miller Fisher Syndrome	5%
211	Brain Diseases, Metabolic, Inborn	4.8%
212	Congenital Hypothyroidism	4.7%
213	Friedreich Ataxia	4.7%
214	Dysautonomia	4.7%
215	Vagus Nerve Disorder	4.7%
216	Glossopharyngeal Neuralgia	4.7%
217	Abducens Nerve Diseases	4.7%
218	Heavy Metal Poisoning, Nervous System	4.7%
219	Neuromuscular Junction Diseases	4.7%
220	Tauopathies	4.7%
221	Trochlear Nerve Diseases	4.7%
222	Peripheral Nervous System Diseases	4.7%
223	ovarian neoplasm	4.7%
224	Myelitis, Transverse	4.7%
225	Mitochondrial Encephalomyopathies	4.7%
226	Opsoclonus-Myoclonus Syndrome	4.6%
227	Central Nervous System Bacterial Infections	4.6%
228	Graves Disease	4.5%
229	Peripheral Nerve Injuries	4.4%
230	Cushing Syndrome	4.4%
231	Hyperaldosteronism	4.4%
232	Hyperparathyroidism, Secondary	4.4%
233	Hypoaldosteronism	4.4%
234	Thyrotoxicosis	4.4%
235	Hyperparathyroidism, Primary	4.4%
236	Thyroid Hormone Resistance Syndrome	4.4%
237	Thyroid Nodule	4.4%
238	Myasthenia Gravis	4.3%
239	Canavan Disease	4.3%
240	Alexander Disease	4.3%
241	Dyskinesia, Drug-Induced	4.3%
242	Cerebral Arterial Diseases	4.2%
243	Vertebrobasilar Insufficiency	4.2%
244	Basilar Artery Stenosis	4.2%
245	Vertebral Artery Stenosis	4.2%
246	Intracranial Hemorrhage, Hypertensive	4.2%
247	Transient Cerebral Ischemia	4.2%
248	Testicular Neoplasms	4.2%
249	Adrenocortical carcinoma	4.1%
250	Wernicke Encephalopathy	4.1%
251	AIDS Dementia Complex	4.1%
252	Auditory Perceptual Disorders	4.1%
253	Lafora Disease	4%
254	Unverricht-Lundborg Syndrome	4%
255	Gestational Diabetes	4%
256	Latent Autoimmune Diabetes in Adults	4%
257	Moyamoya Disease	4%
258	Diabetes Mellitus, Experimental	4%
259	Scrapie	4%
260	Central Cord Syndrome	4%
261	Chorea	3.9%
262	Diffuse Axonal Injury	3.8%
263	Brain Stem Neoplasms	3.8%
264	Putaminal Hemorrhage	3.8%
265	Tuberculosis, Meningeal	3.8%
266	Adrenoleukodystrophy	3.8%
267	Cluster Headache	3.7%
268	Migraine with Aura	3.7%
269	Familial Hemiplegic Migraine	3.7%
270	Chronic Paroxysmal Hemicrania	3.7%
271	SUNCT Syndrome	3.7%
272	Paroxysmal Hemicrania	3.7%
273	Sleep Disorders, Circadian Rhythm	3.7%
274	Myopathy	3.7%
275	Optic Neuropathy	3.7%
276	Cerebral Infarction	3.7%
277	Brain Stem Infarctions	3.7%
278	Progressive bulbar palsy	3.7%
279	Bulbar palsy	3.7%
280	Kernicterus	3.6%
281	Lambert-Eaton Myasthenic Syndrome	3.6%
282	Facial Nerve Diseases	3.6%
283	Craniocerebral Trauma	3.6%
284	Parasomnia	3.6%
285	Dyssomnias	3.6%
286	Botulism	3.6%
287	Central Nervous System Cysts	3.6%
288	Vestibulocochlear Nerve Diseases	3.5%
289	Decerebrate State	3.5%
290	Hemiparesis	3.5%
291	Hydranencephaly	3.5%
292	Meningism	3.5%
293	Neural Tube Defects	3.5%
294	Paresis	3.5%
295	Seizures	3.5%
296	Sensation Disorders	3.5%
297	Tethered Cord Syndrome	3.5%
298	Central Nervous System Neoplasms	3.5%
299	Complex partial seizures	3.5%
300	Iniencephaly	3.5%
301	Craniorachischisis	3.5%
302	Exencephaly	3.5%
303	Monoparesis	3.5%
304	Septo-Optic Dysplasia	3.5%
305	Cortical Dysplasia	3.5%
306	Neurogenic Inflammation	3.5%
307	Gait Disorders, Neurologic	3.5%
308	Neuromuscular Manifestations	3.5%
309	Malformations of Cortical Development	3.5%
310	Sweating, Gustatory	3.5%
311	Auriculotemporal Syndrome	3.5%
312	Guillain-Barre Syndrome	3.5%
313	Vertebral Artery Dissection	3.5%
314	Frontotemporal dementia	3.5%
315	Infarction, Middle Cerebral Artery	3.5%
316	Infarction, Anterior Cerebral Artery	3.5%
317	Infarction, Posterior Cerebral Artery	3.5%
318	Carotid Stenosis	3.4%
319	Intracranial Aneurysm	3.4%
320	Intracranial Arteriosclerosis	3.4%
321	Cerebral Atherosclerosis	3.4%
322	Subarachnoid Hemorrhage	3.4%
323	Cerebral Arteriosclerosis	3.4%
324	Cerebral Hemorrhage	3.4%
325	Hermaphroditism	3.4%
326	Disorders of Sex Development	3.4%
327	Cerebral Thrombosis	3.4%
328	Intracranial Embolism	3.4%
329	Intracranial Thrombosis	3.4%
330	Addison Disease	3.3%
331	Diabetic Angiopathies	3.3%
332	Autoimmune thyroiditis	3.3%
333	Primary Adrenal Insufficiency	3.3%
334	Myxedema	3.3%
335	Orchitis	3.3%
336	Diabetic Cardiomyopathies	3.3%
337	MELAS Syndrome	3.3%
338	Ovarian Hyperstimulation Syndrome	3.2%
339	Meningitis, Cryptococcal	3.2%
340	Diabetic Foot	3.2%
341	Hyperglycemic Hyperosmolar Nonketotic Coma	3.2%
342	Hashimoto Disease	3.2%
343	Meningitis, Listeria	3.2%
344	Brain Contusion	3.2%
345	Torticollis	3.2%
346	Meningitis, Haemophilus	3.2%
347	Meningitis, Pneumococcal	3.2%
348	Olfactory Nerve Injuries	3.1%
349	Causalgia	3.1%
350	Ataxia Telangiectasia	3.1%
351	Spinal Cord Ischemia	3.1%
352	Horner Syndrome	3%
353	Tuberculosis, Central Nervous System	3%
354	Pupil Disorders	3%
355	Neurobehavioral Manifestations	3%
356	Multiple Sclerosis	2.9%
357	Subarachnoid Hemorrhage, Traumatic	2.9%
358	Carotid Artery, Internal, Dissection	2.9%
359	Brain Concussion	2.9%
360	Subacute Sclerosing Panencephalitis	2.9%
361	Multiple Endocrine Neoplasia	2.9%
362	Pancreatic Neoplasm	2.9%
363	Paraneoplastic Encephalomyelitis	2.9%
364	Kallmann Syndrome	2.9%
365	Reflex Sympathetic Dystrophy	2.9%
366	Nocturnal Myoclonus Syndrome	2.9%
367	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	2.8%
368	Uveomeningoencephalitic Syndrome	2.8%
369	granulosa cell tumor	2.8%
370	Carcinoma, Ovarian Epithelial	2.8%
371	Sturge-Weber Syndrome	2.8%
372	Vertigo	2.8%
373	Alcohol-Induced Disorders, Nervous System	2.8%
374	Carotid Artery Thrombosis	2.8%
375	Subclavian Steal Syndrome	2.8%
376	Pick Disease of the Brain	2.8%
377	Lateral Medullary Syndrome	2.8%
378	Giant Cell Arteritis	2.7%
379	Temporal Arteritis	2.7%
380	Facial Nerve Injuries	2.7%
381	Neuromyelitis Optica	2.7%
382	Corpus Luteum Cyst	2.6%
383	Ovarian Cysts	2.6%
384	Diabetic Nephropathy	2.6%
385	Jet Lag Syndrome	2.6%
386	Anovulation	2.6%
387	Diabetic Ketoacidosis	2.6%
388	Oophoritis	2.6%
389	Choroid Plexus Papilloma	2.5%
390	Klinefelter Syndrome	2.5%
391	Ophthalmoplegia	2.5%
392	External Ophthalmoplegia	2.5%
393	Neuroaspergillosis	2.5%
394	Neuritis	2.5%
395	Polyneuritis	2.5%
396	Radiculitis	2.5%
397	Polyneuropathy	2.5%
398	Mononeuritis	2.5%
399	Mononeuropathies	2.5%
400	Brachial Plexus Neuropathies	2.5%
401	Radiculopathy	2.5%
402	Mononeuropathy Multiplex	2.5%
403	Nerve Root Compression	2.5%
404	Voice Disorders	2.4%
405	Voice Disturbance	2.4%
406	Alice in Wonderland Syndrome	2.4%
407	Tuberous Sclerosis	2.4%
408	Smith-Magenis syndrome	2.4%
409	Refsum Disease	2.4%
410	Dural Arteriovenous Fistula	2.4%
411	Myasthenia Gravis, Autoimmune, Experimental	2.3%
412	Waterhouse-Friderichsen Syndrome	2.3%
413	Acrodynia	2.3%
414	Tardive Dyskinesia	2.2%
415	Cerebral Amyloid Angiopathy	2.2%
416	Sinus Thrombosis, Intracranial	2.2%
417	Cryptorchidism	2.2%
418	Gonadal Dysgenesis	2.2%
419	Adrenogenital Syndrome	2.2%
420	Ovotesticular Disorders of Sex Development	2.2%
421	Vocal Cord Paralysis	2.2%
422	Pseudorabies	2.1%
423	Galactosemias	2.1%
424	Urea Cycle Disorders, Inborn	2.1%
425	Tyrosinemias	2.1%
426	Brachial Plexus Neuritis	2%
427	Neuralgic Amyotrophy	2%
428	Neurosyphilis	2%
429	Reflex, Abnormal	2%
430	Hyporeflexia	2%
431	Hyperreflexia	2%
432	Diabetic Retinopathy	2%
433	Charcot-Marie-Tooth Disease	2%
434	Leydig Cell Tumor	2%
435	Polycystic Ovary Syndrome	1.9%
436	Hyperandrogenism	1.9%
437	Myotonia Congenita	1.9%
438	Hematoma, Subdural	1.9%
439	Hematoma, Epidural, Cranial	1.9%
440	Cerebrospinal Fluid Otorrhea	1.9%
441	Cerebrospinal Fluid Rhinorrhea	1.9%
442	Neuritis, Autoimmune, Experimental	1.9%
443	Homocystinuria	1.9%
444	Gait Ataxia	1.9%
445	Leigh Disease	1.9%
446	Myositis	1.9%
447	Optic Atrophy	1.9%
448	Optic Neuritis	1.9%
449	Papilledema	1.9%
450	Strabismus	1.9%
451	Tolosa-Hunt Syndrome	1.9%
452	Isaacs syndrome	1.9%
453	Arsenic Poisoning	1.9%
454	Myotonic Disorders	1.9%
455	Myasthenic Syndromes, Congenital	1.9%
456	Multiple Endocrine Neoplasia Type 1	1.9%
457	Facial Injuries	1.8%
458	Facial Neuralgia	1.8%
459	Sleep Talking	1.8%
460	Manganese Poisoning	1.8%
461	Sleep Disorders, Intrinsic	1.8%
462	Orthostatic intolerance	1.8%
463	Alcohol Withdrawal Seizures	1.8%
464	Anosmia	1.8%
465	Ataxia	1.8%
466	Athetosis	1.8%
467	Catalepsy	1.8%
468	Dystonia	1.8%
469	Hemiplegia	1.8%
470	Locked-In Syndrome	1.8%
471	Meningeal Neoplasms	1.8%
472	Meningomyelocele	1.8%
473	Muscle Hypertonia	1.8%
474	Muscle hypotonia	1.8%
475	Myoclonus	1.8%
476	Myotonia	1.8%
477	Neuralgia	1.8%
478	Paraplegia	1.8%
479	Pseudobulbar Palsy	1.8%
480	Quadriplegia	1.8%
481	Spasm	1.8%
482	Spastic Paraplegia	1.8%
483	Status Epilepticus	1.8%
484	Taste Disorders	1.8%
485	Tremor	1.8%
486	Spina Bifida	1.8%
487	Monoplegia	1.8%
488	Hypokinesia	1.8%
489	Paraparesis	1.8%
490	Bradykinesia	1.8%
491	Waxy flexibility	1.8%
492	Action Tremor	1.8%
493	Resting Tremor	1.8%
494	Dysosmia	1.8%
495	Quadriparesis	1.8%
496	Mercury Poisoning, Nervous System	1.8%
497	Olfaction Disorders	1.8%
498	Myokymia	1.8%
499	Lead Poisoning, Nervous System	1.8%
500	Vestibular Neuronitis	1.8%
501	Somatosensory Disorders	1.8%
502	Neuropathic pain	1.8%
503	Hyperkinesia	1.8%
504	Intention tremor	1.8%
505	West Nile Fever	1.8%
506	Anterior Spinal Artery Syndrome	1.8%
507	Coma, Post-Head Injury	1.8%
508	Fabry Disease	1.8%
509	Lyme Neuroborreliosis	1.7%
510	Cavernous Sinus Thrombosis	1.7%
511	Sagittal Sinus Thrombosis	1.7%
512	Akathisia	1.6%
513	Restlessness	1.6%
514	Psychomotor Agitation	1.6%
515	Menkes Kinky Hair Syndrome	1.6%
516	Multiple Sclerosis, Chronic Progressive	1.6%
517	Multiple Sclerosis, Relapsing-Remitting	1.6%
518	Tarsal Tunnel Syndrome	1.6%
519	Cauda Equina Syndrome	1.6%
520	Hand-Arm Vibration Syndrome	1.6%
521	Myotonic Dystrophy	1.5%
522	Vision Disorders	1.5%
523	Metamorphopsia	1.5%
524	Visual Impairment	1.5%
525	Fibromyalgia	1.5%
526	Optic Neuropathy, Ischemic	1.5%
527	Anterior Ischemic Optic Neuropathy	1.5%
528	Medial Tibial Stress Syndrome	1.5%
529	Facial Hemiatrophy	1.5%
530	Melkersson-Rosenthal Syndrome	1.5%
531	Mitochondrial Myopathies	1.5%
532	Anisocoria	1.5%
533	Confusion	1.5%
534	Facial paralysis	1.5%
535	Lethargy	1.5%
536	Memory Disorders	1.5%
537	Muscle Cramp	1.5%
538	Perceptual Disorders	1.5%
539	Psychomotor Disorders	1.5%
540	Tonic Pupil	1.5%
541	Eosinophilia-Myalgia Syndrome	1.5%
542	Anhedonia	1.5%
543	Disorientation	1.5%
544	Facial Paresis	1.5%
545	Memory Loss	1.5%
546	Hemisensory Neglect	1.5%
547	Dysacusis	1.5%
548	Sleep Bruxism	1.5%
549	Toxoplasmosis, Congenital	1.5%
550	Anencephaly	1.5%
551	Meningocele	1.5%
552	Muscular Atrophy	1.5%
553	Respiratory Paralysis	1.5%
554	Encephalocele	1.5%
555	Malaria, Cerebral	1.5%
556	Tetany	1.5%
557	Neurocysticercosis	1.5%
558	Carcinoma, Pancreatic Ductal	1.4%
559	Zellweger Syndrome	1.4%
560	Gait Apraxia	1.4%
561	Sciatic Neuropathy	1.3%
562	Ulnar Neuropathies	1.3%
563	Lesion of Sciatic Nerve	1.3%
564	Ulnar Neuritis	1.3%
565	Radial nerve compression	1.3%
566	Radial Tunnel Syndrome	1.3%
567	Peroneal Neuropathies	1.3%
568	Radial Neuropathy	1.3%
569	Median Neuropathy	1.3%
570	Sciatic Nerve Palsy	1.3%
571	Femoral Neuropathy	1.3%
572	Tibial Neuropathy	1.3%
573	Ulnar Nerve Palsy	1.3%
574	Postural Orthostatic Tachycardia Syndrome	1.3%
575	Radial nerve palsy	1.3%
576	Hematoma, Subdural, Intracranial	1.3%
577	Hematoma, Subdural, Chronic	1.3%
578	Hematoma, Subdural, Acute	1.3%
579	Acoustic Neuroma	1.3%
580	Carpal Tunnel Syndrome	1.3%
581	neurofibroma	1.3%
582	Turner Syndrome	1.3%
583	Sciatica	1.3%
584	Duane Retraction Syndrome	1.3%
585	Amyloid Neuropathies, Familial	1.3%
586	Consciousness Disorders	1.3%
587	Mental Retardation	1.3%
588	Muscle Weakness	1.3%
589	Depressed Level of Consciousness	1.3%
590	Mental deficiency	1.3%
591	Intellectual Disability	1.3%
592	Alstrom Syndrome	1.3%
593	Mobius Syndrome	1.3%
594	Bell Palsy	1.3%
595	Carbamoyl-Phosphate Synthase I Deficiency Disease	1.2%
596	Catatonia	1.2%
597	Herpes Zoster Oticus	1.2%
598	Familial Periodic Paralysis	1.2%
599	Aphonia	1.2%
600	Sleep Deprivation	1.2%
601	Dysphonia	1.2%
602	insulinoma	1.2%
603	Gastrinoma	1.2%
604	Glucagonoma	1.2%
605	Optic Nerve Glioma	1.2%
606	Carcinoma, Endometrioid	1.2%
607	Glycogen storage disease type II	1.1%
608	Renal Osteodystrophy	1.1%
609	Renal rickets	1.1%
610	Vipoma	1.1%
611	Myalgia	1.1%
612	Neuronal Ceroid-Lipofuscinoses	1%
613	Thoracic Outlet Syndrome	1%
614	Esotropia	1%
615	Exotropia	1%
616	Hypotension, Orthostatic	1%
617	Sleep Apnea Syndromes	1%
618	Polymyositis	1%
619	Post-Exercise Hypotension	1%
620	Disorders of Excessive Somnolence	1%
621	Sleep Initiation and Maintenance Disorders	1%
622	Night Terrors	1%
623	Somnambulism	1%
624	Trigeminal Nerve Disorder	1%
625	Transient Insomnia	1%
626	Sleep Paralysis	1%
627	Chronic Insomnia	1%
628	REM Sleep Behavior Disorder	1%
629	Hypersomnia	1%
630	Dermal Sinus	1%
631	Dysgeusia	1%
632	Formication	1%
633	Hyperalgesia	1%
634	Hyperesthesia	1%
635	Hypesthesia	1%
636	Language Disorders	1%
637	Numbness	1%
638	Paresthesia	1%
639	Paraparesis, Spastic	1%
640	Spina Bifida Cystica	1%
641	Trismus	1%
642	Spina Bifida Occulta	1%
643	Epilepsia Partialis Continua	1%
644	Hypogeusia	1%
645	Meningeal Carcinomatosis	1%
646	Brown-Sequard Syndrome	1%
647	Lissencephaly	1%
648	Polymicrogyria	1%
649	Pachygyria	1%
650	Schizencephaly	1%
651	Lockjaw	1%
652	Allodynia	1%
653	Lead Poisoning, Nervous System, Childhood	1%
654	Lead Poisoning, Nervous System, Adult	1%
655	Periventricular Nodular Heterotopia	1%
656	Ageusia	1%
657	Cubital Tunnel Syndrome	1%
658	Aicardi's syndrome	0.9%
659	Hoarseness	0.9%
660	Cockayne Syndrome	0.9%
661	Alcohol Withdrawal Delirium	0.9%
662	Classical Lissencephalies and Subcortical Band Heterotopias	0.9%
663	Eye Injuries	0.8%
664	Muscular Dystrophy	0.8%
665	Congenital nystagmus	0.8%
666	Orbital Myositis	0.8%
667	Holoprosencephaly	0.8%
668	Diplopia	0.8%
669	Muscle Rigidity	0.8%
670	Muscle Spasticity	0.8%
671	Scotoma	0.8%
672	Photophobia	0.8%
673	Cogwheel Rigidity	0.8%
674	Hemifacial Spasm	0.8%
675	Amaurosis	0.8%
676	Blindness	0.8%
677	Nuchal Rigidity	0.8%
678	Pyomyositis	0.8%
679	Agnosia	0.8%
680	Apraxias	0.8%
681	Hallucinations	0.8%
682	Hemianopsia	0.8%
683	Hyperacusis	0.8%
684	Tinnitus	0.8%
685	Visual Agnosia	0.8%
686	Anosognosia	0.8%
687	Wernicke-Korsakoff Syndrome	0.8%
688	Phonophobia	0.8%
689	Hearing Loss	0.8%
690	Sarcopenia	0.8%
691	Polyradiculopathy	0.8%
692	Gaucher Disease	0.8%
693	Optic Atrophy, Hereditary, Leber	0.7%
694	Alexia	0.7%
695	Dyslexia	0.7%
696	Denys-Drash Syndrome	0.7%
697	Amnesia	0.7%
698	Delirium	0.7%
699	Dissociative Amnesia	0.7%
700	Color blindness	0.7%
701	Global Amnesia	0.7%
702	Cri-du-Chat Syndrome	0.7%
703	Down Syndrome	0.7%
704	Trisomy 21	0.7%
705	POEMS Syndrome	0.7%
706	Meningioma	0.7%
707	Williams Syndrome	0.7%
708	Microcephaly	0.7%
709	Macrocephaly	0.7%
710	Hypokalemic periodic paralysis	0.7%
711	Porencephaly	0.7%
712	Sleep Apnea, Obstructive	0.6%
713	Sleep Apnea, Central	0.6%
714	Kearns-Sayre syndrome	0.6%
715	Narcolepsy	0.6%
716	Trigeminal Neuralgia	0.6%
717	Kleine-Levin Syndrome	0.6%
718	Agraphia	0.6%
719	Anomia	0.6%
720	Cluttering	0.6%
721	Language Development Disorders	0.6%
722	Speech Disorders	0.6%
723	Syncope	0.6%
724	Stupor	0.6%
725	Dysgraphia	0.6%
726	Presyncope	0.6%
727	Dyslalia	0.6%
728	Prader-Willi Syndrome	0.6%
729	Phantom pain	0.6%
730	Phantom Limb Pain	0.6%
731	Niemann-Pick Disease, Type C	0.6%
732	Neurofibrosarcoma	0.6%
733	Tay-Sachs Disease	0.6%
734	Eye Burns	0.5%
735	Welander Distal Myopathy	0.5%
736	Amaurosis Fugax	0.5%
737	Blindness, Cortical	0.5%
738	Dyscalculia	0.5%
739	Rett Syndrome	0.5%
740	Deafness	0.5%
741	Hearing Loss, Sudden	0.5%
742	Gerstmann Syndrome	0.5%
743	Hearing Loss, Bilateral	0.5%
744	Hearing Loss, High-Frequency	0.5%
745	Hearing Loss, Mixed Conductive-Sensorineural	0.5%
746	Prosopagnosia	0.5%
747	Apraxia, Ideomotor	0.5%
748	Charles Bonnet Syndrome	0.5%
749	Hearing Loss, Unilateral	0.5%
750	Complete Hearing Loss	0.5%
751	Alien Hand Syndrome	0.5%
752	Deaf Mutism	0.5%
753	Rubinstein-Taybi Syndrome	0.5%
754	Dermatomyositis	0.4%
755	Corneal Scar	0.4%
756	Muscular Dystrophy, Duchenne	0.4%
757	Retrograde amnesia	0.4%
758	Amnesia, Anterograde	0.4%
759	Cataplexy	0.4%
760	Aphasia	0.4%
761	Articulation Disorders	0.4%
762	Echolalia	0.4%
763	Stuttering	0.4%
764	Dysphasia	0.4%
765	Fragile X Syndrome	0.3%
766	Mutism	0.3%
767	Selective Mutism	0.3%
768	Dysarthria	0.3%
769	Corneal Perforation	0.3%
770	Alexia, Pure	0.2%
771	Mucopolysaccharidosis II	0.2%

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