MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Acrodynia

(UMLS:C0001198)

Definition:: A condition seen primarily in childhood, most often resulting from chronic exposure to MERCURY COMPOUNDS which may result in encephalopathy and POLYNEUROPATHY. Clinical features include pain, swelling and pinkish discoloration of the fingers and toes, weakness in the extremities, extreme irritability, HYPERESTHESIA, and alterations in level of consciousness. (From Menkes, Textbook of Child Neurology, 5th ed, p603)
UMLS ID:: C0001198
MeSH ID:: D000170

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.668.829.025|C10.720.475.600.150

Classification 2:

Name:

Chemically-Induced Disorders
MeSH Tree Number(s):: C25.723.522.875.500.100

Synonym(s)

Acrodynia

ACRODYNIA

Acrodynia caused by mercury

Acrodynia caused by mercury poisoning

Acrodynia due to mercury

Acrodynia due to mercury poisoning

Erythredema polyneuropathy

Feer

Pink disease

10.

Swift

11.

acrodynia

12.

disease pinks

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Celecoxib	FAERS: 1		US FAERS
2	Mercury Compounds		18485443	CTD
3	Phenylmercuric Acetate		18485443	CTD
4	Riluzole			SIDER
5	Thimerosal		14736497	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Brachial Plexus Neuritis	29.8%
2	Neuralgic Amyotrophy	29.8%
3	Causalgia	28.7%
4	Complex Regional Pain Syndromes	27.9%
5	Manganese Poisoning	27.9%
6	Tarsal Tunnel Syndrome	27.1%
7	Cauda Equina Syndrome	27.1%
8	Guillain-Barre Syndrome	26.1%
9	Arsenic Poisoning	25.6%
10	Neuritis	25.3%
11	Polyneuritis	25.3%
12	Radiculitis	25.3%
13	Polyneuropathy	25.3%
14	Mononeuritis	25.3%
15	Mononeuropathies	25.3%
16	Brachial Plexus Neuropathies	25.3%
17	Radiculopathy	25.3%
18	Mononeuropathy Multiplex	25.3%
19	Nerve Root Compression	25.3%
20	Peripheral Nerve Injuries	23.5%
21	Lead Poisoning, Nervous System	23.1%
22	Motor Neuron Disease	22.9%
23	Carpal Tunnel Syndrome	22.7%
24	Sciatica	22.5%
25	Polyradiculoneuropathy	21.5%
26	Polyradiculoneuritis	21.5%
27	Isaacs syndrome	20.6%
28	Botulism	20.6%
29	Cubital Tunnel Syndrome	20.4%
30	Diabetic Neuropathies	20.3%
31	Diabetic Amyotrophy	20.3%
32	Diabetic Autonomic Neuropathy	20.3%
33	Neuralgia	20.2%
34	Neuropathic pain	20.2%
35	Stiff-Person Syndrome	19.7%
36	Reflex Sympathetic Dystrophy	19.5%
37	Neuromuscular Junction Diseases	19.1%
38	Sciatic Neuropathy	18.6%
39	Ulnar Neuropathies	18.6%
40	Lesion of Sciatic Nerve	18.6%
41	Ulnar Neuritis	18.6%
42	Radial nerve compression	18.6%
43	Radial Tunnel Syndrome	18.6%
44	Peroneal Neuropathies	18.6%
45	Radial Neuropathy	18.6%
46	Median Neuropathy	18.6%
47	Sciatic Nerve Palsy	18.6%
48	Femoral Neuropathy	18.6%
49	Tibial Neuropathy	18.6%
50	Ulnar Nerve Palsy	18.6%
51	Radial nerve palsy	18.6%
52	Neuroleptic Malignant Syndrome	18.5%
53	Miller Fisher Syndrome	18.4%
54	Hand-Arm Vibration Syndrome	17.8%
55	MPTP Poisoning	16.8%
56	Akathisia, Drug-Induced	16.7%
57	Dyskinesia, Drug-Induced	16.6%
58	Alcohol-Induced Disorders, Nervous System	16.5%
59	Cranial nerve diseases	16.3%
60	Demyelinating Diseases	16.3%
61	Demyelination	16.3%
62	Chronobiology Disorders	16.3%
63	Neurotoxicity Syndromes	16.3%
64	Myopathy	15.9%
65	Spinal Muscular Atrophy	15.9%
66	Progressive Muscular Atrophy	15.9%
67	Lead Poisoning, Nervous System, Childhood	15.5%
68	Lead Poisoning, Nervous System, Adult	15.5%
69	Poliomyelitis	15.5%
70	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	15.3%
71	Polyradiculopathy	15.3%
72	Thoracic Outlet Syndrome	15.2%
73	Chronic Fatigue Syndrome	14.8%
74	Amyotrophic Lateral Sclerosis	14.8%
75	Progressive bulbar palsy	14.4%
76	Bulbar palsy	14.4%
77	Myasthenia Gravis	14.4%
78	Cadmium poisoning	14.3%
79	Lead Poisoning	14.3%
80	Multiple System Atrophy	14.2%
81	Neuritis, Autoimmune, Experimental	13.9%
82	Trauma, Nervous System	13.5%
83	Nervous System Neoplasms	13.1%
84	Neurologic Manifestations	13.1%
85	Restless Legs Syndrome	13%
86	neurofibroma	12.9%
87	Ocular Motility Disorders	12.8%
88	Cyclophoria	12.8%
89	Charcot-Marie-Tooth Disease	12.6%
90	Lambert-Eaton Myasthenic Syndrome	12.2%
91	Subacute Combined Degeneration	12.1%
92	Encephalomyelitis	12%
93	Prion Diseases	12%
94	Autonomic Dysreflexia	12%
95	Ophthalmoplegic Migraine	11.7%
96	Argyria	11.5%
97	Fluoride Poisoning	11.2%
98	Food Poisoning	11.2%
99	Gas Poisoning	11.2%
100	Mycotoxicosis	11.2%
101	Plant Poisoning	11.2%
102	Organophosphate poisoning	11.2%
103	Meningoencephalitis	11.2%
104	Sleep Wake Disorders	11.1%
105	Parkinson Disease	10.9%
106	POEMS Syndrome	10.7%
107	Marchiafava-Bignami Disease	10.6%
108	Spinal Cord Injuries	10.3%
109	Lewy Body Disease	10.2%
110	Chemical and Drug Induced Liver Injury	10.2%
111	Alcohol Withdrawal Seizures	10.1%
112	Asterixis	10%
113	Ballismus	10%
114	Myositis	10%
115	Myotonic Disorders	10%
116	Myasthenic Syndromes, Congenital	10%
117	Dandy-Walker Syndrome	9.9%
118	Mushroom Poisoning	9.8%
119	Pneumocephalus	9.8%
120	Amyloid Neuropathies, Familial	9.7%
121	Striatonigral Degeneration	9.7%
122	Progressive supranuclear palsy	9.4%
123	Bites and Stings	9.3%
124	Leukoencephalitis, Acute Hemorrhagic	9.3%
125	Myelitis, Transverse	9.2%
126	Myelitis	9.2%
127	Brain Diseases	9.1%
128	Dysautonomia	9.1%
129	Meningitis	9.1%
130	Movement Disorders	9.1%
131	Pachymeningitis	9.1%
132	Spinal Cord Diseases	9.1%
133	Vagus Nerve Disorder	9.1%
134	Glossopharyngeal Neuralgia	9.1%
135	Abducens Nerve Diseases	9.1%
136	Tauopathies	9.1%
137	Trochlear Nerve Diseases	9.1%
138	Myasthenia Gravis, Autoimmune, Experimental	9%
139	Water Intoxication	9%
140	Epidural Abscess	8.9%
141	Olfactory Nerve Injuries	8.9%
142	Myotonic Dystrophy	8.8%
143	Myelinolysis, Central Pontine	8.8%
144	Sleep Disorders, Circadian Rhythm	8.8%
145	Psychoses, Substance-Induced	8.7%
146	Opsoclonus-Myoclonus Syndrome	8.6%
147	Neuromyelitis Optica	8.6%
148	Shy-Drager Syndrome	8.5%
149	Central Nervous System Cysts	8.5%
150	Myotonia Congenita	8.4%
151	Fibromyalgia	8.4%
152	Medial Tibial Stress Syndrome	8.4%
153	Alstrom Syndrome	8.4%
154	Neurofibrosarcoma	8.4%
155	Encephalomyelitis, Acute Disseminated	8.4%
156	Mitochondrial Myopathies	8.3%
157	Eosinophilia-Myalgia Syndrome	8.3%
158	Refsum Disease	8.1%
159	Dystonia Musculorum Deformans	7.9%
160	Subdural Effusion	7.8%
161	Parkinsonian Disorders	7.8%
162	Nocturnal Myoclonus Syndrome	7.8%
163	Facial Nerve Injuries	7.8%
164	Neuromuscular Diseases	7.7%
165	Brain Injuries	7.7%
166	Alcohol Withdrawal Delirium	7.6%
167	Brain Neoplasms	7.6%
168	Multiple Sclerosis	7.6%
169	Spinal Cord Neoplasms	7.6%
170	Central Nervous System Infection	7.6%
171	Optic Neuropathy	7.6%
172	Leukoencephalopathy, Progressive Multifocal	7.6%
173	Horner Syndrome	7.5%
174	Facial Nerve Diseases	7.4%
175	Craniocerebral Trauma	7.4%
176	Parasomnia	7.4%
177	Dyssomnias	7.4%
178	Vestibulocochlear Nerve Diseases	7.3%
179	Decerebrate State	7.3%
180	Hemiparesis	7.3%
181	Hydranencephaly	7.3%
182	Meningism	7.3%
183	Neural Tube Defects	7.3%
184	Paresis	7.3%
185	Seizures	7.3%
186	Sensation Disorders	7.3%
187	Tethered Cord Syndrome	7.3%
188	Central Nervous System Neoplasms	7.3%
189	Complex partial seizures	7.3%
190	Iniencephaly	7.3%
191	Craniorachischisis	7.3%
192	Exencephaly	7.3%
193	Monoparesis	7.3%
194	Septo-Optic Dysplasia	7.3%
195	Cortical Dysplasia	7.3%
196	Neurogenic Inflammation	7.3%
197	Gait Disorders, Neurologic	7.3%
198	Neuromuscular Manifestations	7.3%
199	Malformations of Cortical Development	7.3%
200	Drug toxicity	7.3%
201	Sweating, Gustatory	7.3%
202	Auriculotemporal Syndrome	7.3%
203	Polymyositis	7.2%
204	Familial Periodic Paralysis	7.1%
205	Epilepsy, Post-Traumatic	6.9%
206	Limbic Encephalitis	6.9%
207	Huntington Disease	6.9%
208	Lupus Vasculitis, Central Nervous System	6.7%
209	Vasculitis, Central Nervous System	6.6%
210	Brain Abscess	6.6%
211	Ophthalmoplegia	6.6%
212	External Ophthalmoplegia	6.6%
213	Scrapie	6.6%
214	Central Cord Syndrome	6.6%
215	Jet Lag Syndrome	6.6%
216	Presenile dementia	6.5%
217	Senile dementia	6.5%
218	Meningitis, Bacterial	6.5%
219	Meningitis, Fungal	6.5%
220	Mitochondrial Encephalomyopathies	6.5%
221	Chorea	6.5%
222	Meige Syndrome	6.5%
223	Cerebral Ventriculitis	6.5%
224	Tuberous Sclerosis	6.4%
225	Canavan Disease	6.3%
226	Alexander Disease	6.3%
227	Pupil Disorders	6.3%
228	Neurobehavioral Manifestations	6.3%
229	Lafora Disease	6.2%
230	Unverricht-Lundborg Syndrome	6.2%
231	Paraneoplastic Encephalomyelitis	6.2%
232	Myalgia	6.1%
233	Carbon Monoxide Poisoning	6.1%
234	Ciguatera Poisoning	6.1%
235	Ergotism	6.1%
236	Shellfish Poisoning	6.1%
237	Uveomeningoencephalitic Syndrome	6.1%
238	Muscular Dystrophy	6.1%
239	Sturge-Weber Syndrome	6.1%
240	Vertigo	6.1%
241	Orbital Myositis	6.1%
242	Drug abuse	6%
243	Substance Dependence	6%
244	Substance-Related Disorders	6%
245	Drug Dependence	6%
246	Ataxia Telangiectasia	6%
247	Pyomyositis	6%
248	Dementia, Vascular	6%
249	Cerebellar Neoplasms	6%
250	Brain Hemorrhage, Traumatic	6%
251	Vocal Cord Paralysis	5.8%
252	Posterior Leukoencephalopathy Syndrome	5.8%
253	Posterior reversible encephalopathy syndrome	5.8%
254	Akinetic Mutism	5.7%
255	Anoxic Encephalopathy	5.7%
256	Arachnoiditis	5.7%
257	Basal Ganglia Diseases	5.7%
258	Brain Damage, Chronic	5.7%
259	Cerebellar Diseases	5.7%
260	Encephalitis	5.7%
261	Encephalomalacia	5.7%
262	Epilepsy	5.7%
263	Hydrocephalus	5.7%
264	Congenital Hydrocephalus	5.7%
265	Hypothalamic Diseases	5.7%
266	Aseptic Meningitis	5.7%
267	Syringomyelia	5.7%
268	Thalamic Diseases	5.7%
269	Intracranial Hypertension	5.7%
270	Aura	5.7%
271	Leukoencephalopathy	5.7%
272	Essential Tremor	5.7%
273	Neuroaxonal Dystrophies	5.7%
274	Familial Tremor	5.7%
275	Headache Disorders	5.7%
276	Intracranial Hypotension	5.7%
277	Brain Edema	5.7%
278	Brain Hypoxia	5.7%
279	Aqueductal Stenosis	5.7%
280	Pneumorrhachis	5.7%
281	Writer's Cramp	5.7%
282	Brain Death	5.7%
283	Coma, Post-Head Injury	5.7%
284	Friedreich Ataxia	5.7%
285	Amblyopia	5.6%
286	Paraneoplastic Cerebellar Degeneration	5.6%
287	Cerebrospinal Fluid Otorrhea	5.6%
288	Cerebrospinal Fluid Rhinorrhea	5.6%
289	Gait Ataxia	5.6%
290	Chemical and Drug Induced Liver Injury, Chronic	5.5%
291	Creutzfeldt-Jakob disease	5.4%
292	Basal Ganglia Cerebrovascular Disease	5.4%
293	Carotid Artery Injuries	5.4%
294	Brain Injuries, Diffuse	5.4%
295	Traumatic Brain Injury	5.4%
296	Cerebellar Ataxia	5.4%
297	Supratentorial Neoplasms	5.4%
298	Torticollis	5.4%
299	Multiple Sclerosis, Chronic Progressive	5.4%
300	Multiple Sclerosis, Relapsing-Remitting	5.4%
301	Hepatolenticular Degeneration	5.4%
302	Voice Disorders	5.3%
303	Voice Disturbance	5.3%
304	Smith-Magenis syndrome	5.2%
305	Tuberculosis, Meningeal	5.2%
306	Dural Arteriovenous Fistula	5.2%
307	Myoclonic Epilepsy	5.1%
308	Epilepsy, Temporal Lobe	5.1%
309	Epilepsy, Rolandic	5.1%
310	Benign Rolandic Epilepsy	5.1%
311	Hypokalemic periodic paralysis	5.1%
312	Insect Bites and Stings	5%
313	Heavy Metal Poisoning, Nervous System	5%
314	Akathisia	4.9%
315	Restlessness	4.9%
316	Psychomotor Agitation	4.9%
317	Salmonella food poisoning	4.9%
318	Vascular Headaches	4.9%
319	Welander Distal Myopathy	4.9%
320	Hypoxia-Ischemia, Brain	4.8%
321	Alice in Wonderland Syndrome	4.8%
322	Tardive Dyskinesia	4.8%
323	Persistent Vegetative State	4.8%
324	Optic Nerve Glioma	4.7%
325	Leukomalacia, Periventricular	4.7%
326	Brain Concussion	4.7%
327	Brain Diseases, Metabolic	4.7%
328	Cerebrovascular Disorders	4.7%
329	Optic Atrophy	4.7%
330	Optic Neuritis	4.7%
331	Papilledema	4.7%
332	Strabismus	4.7%
333	Tolosa-Hunt Syndrome	4.7%
334	Cerebrovascular Insufficiency	4.7%
335	Dementia	4.7%
336	Central Nervous System Fungal Infections	4.7%
337	Conus Medullaris Syndrome	4.7%
338	Spinal Cord Vascular Diseases	4.7%
339	Facial Injuries	4.6%
340	Facial Neuralgia	4.6%
341	Sleep Talking	4.6%
342	Sleep Disorders, Intrinsic	4.6%
343	Orthostatic intolerance	4.6%
344	Anosmia	4.6%
345	Ataxia	4.6%
346	Athetosis	4.6%
347	Catalepsy	4.6%
348	Dystonia	4.6%
349	Hemiplegia	4.6%
350	Locked-In Syndrome	4.6%
351	Meningeal Neoplasms	4.6%
352	Meningomyelocele	4.6%
353	Muscle Hypertonia	4.6%
354	Muscle hypotonia	4.6%
355	Myoclonus	4.6%
356	Myotonia	4.6%
357	Paraplegia	4.6%
358	Pseudobulbar Palsy	4.6%
359	Quadriplegia	4.6%
360	Spasm	4.6%
361	Spastic Paraplegia	4.6%
362	Status Epilepticus	4.6%
363	Taste Disorders	4.6%
364	Tremor	4.6%
365	Spina Bifida	4.6%
366	Monoplegia	4.6%
367	Hypokinesia	4.6%
368	Paraparesis	4.6%
369	Bradykinesia	4.6%
370	Waxy flexibility	4.6%
371	Action Tremor	4.6%
372	Resting Tremor	4.6%
373	Dysosmia	4.6%
374	Quadriparesis	4.6%
375	Olfaction Disorders	4.6%
376	Myokymia	4.6%
377	Vestibular Neuronitis	4.6%
378	Somatosensory Disorders	4.6%
379	Hyperkinesia	4.6%
380	Intention tremor	4.6%
381	MELAS Syndrome	4.6%
382	Toxoplasmosis, Cerebral	4.5%
383	Reflex, Abnormal	4.5%
384	Hyporeflexia	4.5%
385	Hyperreflexia	4.5%
386	Juvenile Myoclonic Epilepsy	4.5%
387	Myoclonic Epilepsies, Progressive	4.5%
388	Vertebral Artery Dissection	4.5%
389	Amnesia, Transient Global	4.5%
390	Pituitary Adenoma	4.5%
391	Pituitary Neoplasms	4.5%
392	Gait Apraxia	4.4%
393	Diffuse Axonal Injury	4.3%
394	Brain Stem Neoplasms	4.3%
395	Dermatomyositis	4.3%
396	Kearns-Sayre syndrome	4.2%
397	Psychoses, Alcoholic	4.2%
398	Muscular Dystrophy, Duchenne	4.2%
399	Meningitis, Cryptococcal	4.2%
400	Peripheral Nervous System Diseases	4.1%
401	Meningitis, Listeria	4.1%
402	Meningitis, Haemophilus	4.1%
403	Meningitis, Pneumococcal	4.1%
404	Frontotemporal dementia	4.1%
405	Basal Ganglia Hemorrhage	4.1%
406	Cerebral Palsy	4%
407	Epilepsies, Partial	4%
408	Epilepsy, Generalized	4%
409	Pseudotumor Cerebri	4%
410	Hypertensive Encephalopathy	4%
411	Simple Partial Seizures	4%
412	Epilepsy, Reflex	4%
413	Postural Orthostatic Tachycardia Syndrome	4%
414	Headache Disorders, Primary	4%
415	Headache Disorders, Secondary	4%
416	Medication overuse headache	4%
417	Vision Disorders	3.9%
418	Metamorphopsia	3.9%
419	Visual Impairment	3.9%
420	Optic Neuropathy, Ischemic	3.9%
421	Anterior Ischemic Optic Neuropathy	3.9%
422	Central Nervous System Bacterial Infections	3.9%
423	Facial Hemiatrophy	3.9%
424	Melkersson-Rosenthal Syndrome	3.9%
425	Anisocoria	3.9%
426	Confusion	3.9%
427	Facial paralysis	3.9%
428	Lethargy	3.9%
429	Memory Disorders	3.9%
430	Muscle Cramp	3.9%
431	Perceptual Disorders	3.9%
432	Psychomotor Disorders	3.9%
433	Tonic Pupil	3.9%
434	Anhedonia	3.9%
435	Disorientation	3.9%
436	Facial Paresis	3.9%
437	Memory Loss	3.9%
438	Hemisensory Neglect	3.9%
439	Dysacusis	3.9%
440	Subarachnoid Hemorrhage, Traumatic	3.8%
441	Carotid Artery, Internal, Dissection	3.8%
442	Sleep Bruxism	3.8%
443	Anencephaly	3.8%
444	Meningocele	3.8%
445	Muscular Atrophy	3.8%
446	Respiratory Paralysis	3.8%
447	Encephalocele	3.8%
448	Adrenoleukodystrophy	3.8%
449	Tetany	3.8%
450	Acoustic Neuroma	3.8%
451	Subacute Sclerosing Panencephalitis	3.8%
452	Anticholinergic Syndrome	3.7%
453	Serotonin Syndrome	3.7%
454	Propofol Infusion Syndrome	3.7%
455	Pituitary Apoplexy	3.7%
456	Choroid Plexus Papilloma	3.7%
457	Brain Contusion	3.7%
458	Brain Infarction	3.7%
459	Putaminal Hemorrhage	3.6%
460	Classical Lissencephalies and Subcortical Band Heterotopias	3.6%
461	Auditory Perceptual Disorders	3.6%
462	Giant Cell Arteritis	3.6%
463	Temporal Arteritis	3.6%
464	Infarction, Middle Cerebral Artery	3.5%
465	Infarction, Anterior Cerebral Artery	3.5%
466	Infarction, Posterior Cerebral Artery	3.5%
467	Pituitary Diseases	3.4%
468	Duane Retraction Syndrome	3.4%
469	Consciousness Disorders	3.3%
470	Mental Retardation	3.3%
471	Muscle Weakness	3.3%
472	Depressed Level of Consciousness	3.3%
473	Mental deficiency	3.3%
474	Intellectual Disability	3.3%
475	Mobius Syndrome	3.3%
476	Bell Palsy	3.3%
477	Catatonia	3.3%
478	Herpes Zoster Oticus	3.3%
479	Aphonia	3.3%
480	Sleep Deprivation	3.3%
481	Dysphonia	3.3%
482	Carotid Artery Diseases	3.3%
483	Brain Ischemia	3.3%
484	Esotropia	3.3%
485	Exotropia	3.3%
486	Hypotension, Orthostatic	3.3%
487	Sleep Apnea Syndromes	3.3%
488	Cerebrovascular accident	3.3%
489	Kluver-Bucy Syndrome	3.3%
490	Vasospasm, Intracranial	3.3%
491	Spinal Cord Ischemia	3.3%
492	Intracranial Arterial Diseases	3.3%
493	Post-Exercise Hypotension	3.3%
494	Acrodynia	3.2%
495	Disorders of Excessive Somnolence	3.2%
496	Sleep Initiation and Maintenance Disorders	3.2%
497	Night Terrors	3.2%
498	Somnambulism	3.2%
499	Trigeminal Nerve Disorder	3.2%
500	Transient Insomnia	3.2%
501	Sleep Paralysis	3.2%
502	Chronic Insomnia	3.2%
503	REM Sleep Behavior Disorder	3.2%
504	Hypersomnia	3.2%
505	Dermal Sinus	3.2%
506	Dysgeusia	3.2%
507	Formication	3.2%
508	Hyperalgesia	3.2%
509	Hyperesthesia	3.2%
510	Hypesthesia	3.2%
511	Language Disorders	3.2%
512	Numbness	3.2%
513	Paresthesia	3.2%
514	Post-Traumatic Headache	3.2%
515	Tension Headache	3.2%
516	Paraparesis, Spastic	3.2%
517	Spina Bifida Cystica	3.2%
518	Trismus	3.2%
519	Spina Bifida Occulta	3.2%
520	Epilepsy, Complex Partial	3.2%
521	Epilepsia Partialis Continua	3.2%
522	Migraine Disorders	3.2%
523	Hypogeusia	3.2%
524	Meningeal Carcinomatosis	3.2%
525	Brown-Sequard Syndrome	3.2%
526	Lissencephaly	3.2%
527	Polymicrogyria	3.2%
528	Pachygyria	3.2%
529	Schizencephaly	3.2%
530	Abdominal Migraine	3.2%
531	Status Migrainosus	3.2%
532	Lockjaw	3.2%
533	Cervicogenic Headache	3.2%
534	Allodynia	3.2%
535	Periventricular Nodular Heterotopia	3.2%
536	Ageusia	3.2%
537	Tuberculosis, Central Nervous System	3.2%
538	Alexia	3.2%
539	Dyslexia	3.2%
540	Cerebral Infarction	3.2%
541	Brain Stem Infarctions	3.2%
542	Wernicke Encephalopathy	3.1%
543	Hematoma, Subdural	3%
544	Hematoma, Epidural, Cranial	3%
545	Marijuana Abuse	3%
546	Opioid-Related Disorders	3%
547	Nicotine Dependence	3%
548	Opioid abuse	3%
549	Phencyclidine Abuse	3%
550	Substance Abuse, Intravenous	3%
551	Substance Withdrawal Syndrome	3%
552	Tobacco Use Disorder	3%
553	Alcohol-Related Disorders	3%
554	Amphetamine-Related Disorders	3%
555	Cocaine-Related Disorders	3%
556	Metabolic Side Effects of Drugs and Substances	3%
557	Moyamoya Disease	3%
558	West Nile Fever	3%
559	Injection Site Reaction	3%
560	Infusion site reaction	3%
561	Drug Overdose	3%
562	Lateral Medullary Syndrome	3%
563	Optic Atrophy, Hereditary, Leber	2.9%
564	Neuronal Ceroid-Lipofuscinoses	2.8%
565	Cluster Headache	2.8%
566	Migraine with Aura	2.8%
567	Familial Hemiplegic Migraine	2.8%
568	Chronic Paroxysmal Hemicrania	2.8%
569	SUNCT Syndrome	2.8%
570	Paroxysmal Hemicrania	2.8%
571	Eye Injuries	2.8%
572	Congenital nystagmus	2.8%
573	Diplopia	2.7%
574	Muscle Rigidity	2.7%
575	Muscle Spasticity	2.7%
576	Scotoma	2.7%
577	Photophobia	2.7%
578	Cogwheel Rigidity	2.7%
579	Hemifacial Spasm	2.7%
580	Amaurosis	2.7%
581	Blindness	2.7%
582	Nuchal Rigidity	2.7%
583	Reye Syndrome	2.7%
584	Neuroaspergillosis	2.7%
585	Intracranial Embolism and Thrombosis	2.7%
586	Hepatic Encephalopathy	2.7%
587	Agnosia	2.7%
588	Apraxias	2.7%
589	Hallucinations	2.7%
590	Hemianopsia	2.7%
591	Hyperacusis	2.7%
592	Tinnitus	2.7%
593	Visual Agnosia	2.7%
594	Anosognosia	2.7%
595	Wernicke-Korsakoff Syndrome	2.7%
596	Phonophobia	2.7%
597	Hearing Loss	2.7%
598	Sarcopenia	2.7%
599	Empty Sella Syndrome	2.6%
600	Hyperpituitarism	2.6%
601	Hypopituitarism	2.6%
602	Hypophysitis	2.6%
603	Mercury Poisoning, Nervous System	2.6%
604	Aicardi's syndrome	2.6%
605	Cerebral Arterial Diseases	2.6%
606	Vertebrobasilar Insufficiency	2.6%
607	Anterior Spinal Artery Syndrome	2.6%
608	Basilar Artery Stenosis	2.6%
609	Vertebral Artery Stenosis	2.6%
610	Sleep Apnea, Obstructive	2.6%
611	Sleep Apnea, Central	2.6%
612	Intracranial Hemorrhage, Hypertensive	2.6%
613	Transient Cerebral Ischemia	2.6%
614	Hoarseness	2.6%
615	Narcolepsy	2.6%
616	Trigeminal Neuralgia	2.6%
617	Kleine-Levin Syndrome	2.6%
618	Hematoma, Subdural, Intracranial	2.6%
619	Hematoma, Subdural, Chronic	2.6%
620	Hematoma, Subdural, Acute	2.6%
621	Agraphia	2.6%
622	Anomia	2.6%
623	Cluttering	2.6%
624	Language Development Disorders	2.6%
625	Speech Disorders	2.6%
626	Syncope	2.6%
627	Stupor	2.6%
628	Dysgraphia	2.6%
629	Presyncope	2.6%
630	Dyslalia	2.6%
631	Cockayne Syndrome	2.6%
632	Neonatal Abstinence Syndrome	2.5%
633	Pseudorabies	2.4%
634	Tick Paralysis	2.4%
635	Amnesia	2.3%
636	Delirium	2.3%
637	Dissociative Amnesia	2.3%
638	Color blindness	2.3%
639	Global Amnesia	2.3%
640	Cri-du-Chat Syndrome	2.3%
641	Down Syndrome	2.3%
642	Brain Diseases, Metabolic, Inborn	2.3%
643	Trisomy 21	2.3%
644	Meningioma	2.3%
645	Williams Syndrome	2.3%
646	Microcephaly	2.3%
647	Macrocephaly	2.3%
648	Neurosyphilis	2.3%
649	Holoprosencephaly	2.3%
650	Porencephaly	2.3%
651	Hyperprolactinemia	2.3%
652	Subclavian Steal Syndrome	2.2%
653	Pick Disease of the Brain	2.2%
654	Cataplexy	2.2%
655	Aphasia	2.2%
656	Articulation Disorders	2.2%
657	Echolalia	2.2%
658	Stuttering	2.2%
659	Dysphasia	2.2%
660	Toxoplasmosis, Congenital	2.2%
661	Eye Burns	2.2%
662	Malaria, Cerebral	2.2%
663	Cardiotoxicity	2.2%
664	Carotid Stenosis	2.2%
665	Intracranial Aneurysm	2.2%
666	Neurocysticercosis	2.2%
667	Amaurosis Fugax	2.2%
668	Blindness, Cortical	2.2%
669	Dyscalculia	2.2%
670	Intracranial Arteriosclerosis	2.2%
671	Cerebral Atherosclerosis	2.2%
672	Rett Syndrome	2.2%
673	Subarachnoid Hemorrhage	2.2%
674	Cerebral Arteriosclerosis	2.2%
675	Cerebral Hemorrhage	2.2%
676	Cerebral Thrombosis	2.1%
677	Intracranial Embolism	2.1%
678	Intracranial Thrombosis	2.1%
679	Deafness	2.1%
680	Hearing Loss, Sudden	2.1%
681	Gerstmann Syndrome	2.1%
682	Hearing Loss, Bilateral	2.1%
683	Hearing Loss, High-Frequency	2.1%
684	Hearing Loss, Mixed Conductive-Sensorineural	2.1%
685	Prosopagnosia	2.1%
686	Apraxia, Ideomotor	2.1%
687	Charles Bonnet Syndrome	2.1%
688	Hearing Loss, Unilateral	2.1%
689	Complete Hearing Loss	2.1%
690	Alien Hand Syndrome	2.1%
691	Deaf Mutism	2.1%
692	Dysarthria	2.1%
693	Prader-Willi Syndrome	2%
694	Alcohol-Induced Disorders	2%
695	AIDS Dementia Complex	2%
696	Phantom pain	2%
697	Phantom Limb Pain	2%
698	Waterhouse-Friderichsen Syndrome	2%
699	Lyme Neuroborreliosis	2%
700	Menkes Kinky Hair Syndrome	2%
701	Mutism	1.9%
702	Selective Mutism	1.9%
703	Acromegaly	1.9%
704	Corneal Scar	1.9%
705	Cerebral Amyloid Angiopathy	1.9%
706	Sinus Thrombosis, Intracranial	1.9%
707	Retrograde amnesia	1.8%
708	Amnesia, Anterograde	1.8%
709	Kernicterus	1.8%
710	Carotid Artery Thrombosis	1.8%
711	Alexia, Pure	1.7%
712	Cavernous Sinus Thrombosis	1.7%
713	Sagittal Sinus Thrombosis	1.7%
714	Alcohol Use Disorder	1.6%
715	Alcoholic Intoxication	1.6%
716	Heroin Dependence	1.6%
717	Morphine Dependence	1.6%
718	Alcohol abuse	1.6%
719	Rubinstein-Taybi Syndrome	1.6%
720	Corneal Perforation	1.6%
721	Fragile X Syndrome	1.6%
722	Fabry Disease	1.5%
723	Nelson Syndrome	1.5%
724	Galactosemias	1.4%
725	Urea Cycle Disorders, Inborn	1.4%
726	Tyrosinemias	1.4%
727	Prolactinoma	1.4%
728	Growth Hormone-Secreting Pituitary Adenoma	1.4%
729	Drug Eruptions	1.4%
730	Binge Drinking	1.4%
731	Homocystinuria	1.3%
732	Leigh Disease	1.3%
733	Mucopolysaccharidosis II	1.2%
734	Carbamoyl-Phosphate Synthase I Deficiency Disease	1.1%
735	Asthma, Aspirin-Induced	1%
736	Glycogen storage disease type II	1%
737	Zellweger Syndrome	1%
738	Cardiomyopathy, Alcoholic	1%
739	Pancreatitis, Alcoholic	1%
740	Gaucher Disease	0.9%
741	Fetal Alcohol Spectrum Disorders	0.8%
742	Acute Generalized Exanthematous Pustulosis	0.8%
743	Tay-Sachs Disease	0.8%
744	Niemann-Pick Disease, Type C	0.8%
745	Erythema Nodosum	0.7%
746	Serum Sickness	0.7%
747	Fatty Liver, Alcoholic	0.5%
748	Hepatitis, Alcoholic	0.5%
749	Liver Cirrhosis, Alcoholic	0.5%
750	Toxic Epidermal Necrolysis	0.5%
751	Stevens-Johnson Syndrome	0.5%

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