MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Lead Poisoning, Nervous System

(UMLS:C0751859)

Definition:: Injury to the nervous system secondary to exposure to lead compounds. Two distinct clinical patterns occur in children (LEAD POISONING, NERVOUS SYSTEM, CHILDHOOD) and adults (LEAD POISONING, NERVOUS SYSTEM, ADULT). In children, lead poisoning typically produces an encephalopathy. In adults, exposure to toxic levels of lead is associated with a peripheral neuropathy.
UMLS ID:: C0751859
MeSH ID:: D020263

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.720.475.400

Classification 2:

Name:

Chemically-Induced Disorders
MeSH Tree Number(s):: C25.723.522.750.500

Synonym(s)

Lead Poisoning, Nervous System

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Quercetin		23855546	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Manganese Poisoning	40.5%
2	Arsenic Poisoning	36.1%
3	Mercury Poisoning, Nervous System	34.4%
4	Acrodynia	23.1%
5	Cadmium poisoning	23.1%
6	Mercury Poisoning	23.1%
7	Neuroleptic Malignant Syndrome	20%
8	Alcohol-Induced Disorders, Nervous System	19.3%
9	MPTP Poisoning	17.4%
10	Argyria	17.4%
11	Akathisia, Drug-Induced	17.3%
12	Botulism	17.2%
13	Fluoride Poisoning	16.9%
14	Food Poisoning	16.9%
15	Gas Poisoning	16.9%
16	Mycotoxicosis	16.9%
17	Plant Poisoning	16.9%
18	Organophosphate poisoning	16.9%
19	Dyskinesia, Drug-Induced	16.3%
20	Mushroom Poisoning	14.9%
21	Chemical and Drug Induced Liver Injury	13.8%
22	Bites and Stings	13.3%
23	Neurotoxicity Syndromes	13.3%
24	Water Intoxication	12.6%
25	Cranial nerve diseases	11.8%
26	Demyelinating Diseases	11.8%
27	Demyelination	11.8%
28	Neuromuscular Diseases	11.8%
29	Chronobiology Disorders	11.8%
30	Psychoses, Substance-Induced	11.4%
31	Alcohol Withdrawal Seizures	10.8%
32	Drug toxicity	10.6%
33	Motor Neuron Disease	10.3%
34	Carbon Monoxide Poisoning	9.9%
35	Ciguatera Poisoning	9.9%
36	Ergotism	9.9%
37	Shellfish Poisoning	9.9%
38	Multiple System Atrophy	9.4%
39	Alcohol Withdrawal Delirium	9.2%
40	Trauma, Nervous System	9.2%
41	Stiff-Person Syndrome	9%
42	Nervous System Neoplasms	8.8%
43	Neurologic Manifestations	8.8%
44	Ocular Motility Disorders	8.5%
45	Cyclophoria	8.5%
46	Polyradiculoneuropathy	8.4%
47	Polyradiculoneuritis	8.4%
48	Encephalomyelitis	8.4%
49	Prion Diseases	8.4%
50	Autonomic Dysreflexia	8.4%
51	Complex Regional Pain Syndromes	8.4%
52	Drug abuse	8.3%
53	Substance Dependence	8.3%
54	Substance-Related Disorders	8.3%
55	Drug Dependence	8.3%
56	Restless Legs Syndrome	8.2%
57	Spinal Muscular Atrophy	7.9%
58	Progressive Muscular Atrophy	7.9%
59	Chemical and Drug Induced Liver Injury, Chronic	7.9%
60	Subacute Combined Degeneration	7.7%
61	Meningoencephalitis	7.7%
62	Parkinson Disease	7.6%
63	Insect Bites and Stings	7.6%
64	Amyotrophic Lateral Sclerosis	7.5%
65	Marchiafava-Bignami Disease	7.5%
66	Ophthalmoplegic Migraine	7.4%
67	Salmonella food poisoning	7.3%
68	Sleep Wake Disorders	7.2%
69	Spinal Cord Injuries	7%
70	Lewy Body Disease	6.8%
71	Peripheral Nerve Injuries	6.8%
72	Guillain-Barre Syndrome	6.8%
73	Striatonigral Degeneration	6.8%
74	Brain Diseases	6.7%
75	Dysautonomia	6.7%
76	Meningitis	6.7%
77	Movement Disorders	6.7%
78	Pachymeningitis	6.7%
79	Spinal Cord Diseases	6.7%
80	Vagus Nerve Disorder	6.7%
81	Glossopharyngeal Neuralgia	6.7%
82	Abducens Nerve Diseases	6.7%
83	Neuromuscular Junction Diseases	6.7%
84	Tauopathies	6.7%
85	Trochlear Nerve Diseases	6.7%
86	Peripheral Nervous System Diseases	6.7%
87	Myasthenia Gravis	6.7%
88	Asterixis	6.7%
89	Ballismus	6.7%
90	Dandy-Walker Syndrome	6.6%
91	Myelitis	6.6%
92	Progressive bulbar palsy	6.6%
93	Bulbar palsy	6.6%
94	Pneumocephalus	6.6%
95	Poliomyelitis	6.6%
96	Causalgia	6.5%
97	Progressive supranuclear palsy	6.2%
98	Leukoencephalitis, Acute Hemorrhagic	6.1%
99	Psychoses, Alcoholic	6%
100	Epidural Abscess	6%
101	Olfactory Nerve Injuries	6%
102	Myelinolysis, Central Pontine	6%
103	Miller Fisher Syndrome	6%
104	Myelitis, Transverse	5.9%
105	Chronic Fatigue Syndrome	5.8%
106	Lambert-Eaton Myasthenic Syndrome	5.8%
107	Shy-Drager Syndrome	5.8%
108	Sleep Disorders, Circadian Rhythm	5.8%
109	Reflex Sympathetic Dystrophy	5.7%
110	Subdural Effusion	5.7%
111	Parkinsonian Disorders	5.7%
112	Nocturnal Myoclonus Syndrome	5.7%
113	Encephalomyelitis, Acute Disseminated	5.7%
114	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	5.7%
115	Anticholinergic Syndrome	5.6%
116	Serotonin Syndrome	5.6%
117	Propofol Infusion Syndrome	5.6%
118	Central Nervous System Cysts	5.6%
119	Neuromyelitis Optica	5.5%
120	Opsoclonus-Myoclonus Syndrome	5.5%
121	Dystonia Musculorum Deformans	5.5%
122	Central Nervous System Infection	5.3%
123	Myopathy	5.3%
124	Optic Neuropathy	5.3%
125	Brain Injuries	5.3%
126	Brain Neoplasms	5.3%
127	Multiple Sclerosis	5.3%
128	Spinal Cord Neoplasms	5.3%
129	Facial Nerve Injuries	5.2%
130	Facial Nerve Diseases	5.1%
131	Craniocerebral Trauma	5.1%
132	Parasomnia	5.1%
133	Dyssomnias	5.1%
134	Vestibulocochlear Nerve Diseases	5%
135	Decerebrate State	5%
136	Hemiparesis	5%
137	Hydranencephaly	5%
138	Meningism	5%
139	Neural Tube Defects	5%
140	Paresis	5%
141	Seizures	5%
142	Sensation Disorders	5%
143	Tethered Cord Syndrome	5%
144	Central Nervous System Neoplasms	5%
145	Complex partial seizures	5%
146	Iniencephaly	5%
147	Craniorachischisis	5%
148	Exencephaly	5%
149	Monoparesis	5%
150	Septo-Optic Dysplasia	5%
151	Cortical Dysplasia	5%
152	Neurogenic Inflammation	5%
153	Gait Disorders, Neurologic	5%
154	Neuromuscular Manifestations	5%
155	Malformations of Cortical Development	5%
156	Sweating, Gustatory	5%
157	Auriculotemporal Syndrome	5%
158	Horner Syndrome	5%
159	Leukoencephalopathy, Progressive Multifocal	4.9%
160	Meige Syndrome	4.9%
161	Brachial Plexus Neuritis	4.9%
162	Neuralgic Amyotrophy	4.9%
163	Cerebral Ventriculitis	4.9%
164	Epilepsy, Post-Traumatic	4.9%
165	Tick Paralysis	4.9%
166	Limbic Encephalitis	4.7%
167	Scrapie	4.7%
168	Central Cord Syndrome	4.7%
169	Presenile dementia	4.6%
170	Senile dementia	4.6%
171	Meningitis, Bacterial	4.6%
172	Meningitis, Fungal	4.6%
173	Chorea	4.6%
174	Huntington Disease	4.6%
175	Myasthenia Gravis, Autoimmune, Experimental	4.5%
176	Lafora Disease	4.5%
177	Unverricht-Lundborg Syndrome	4.5%
178	Tarsal Tunnel Syndrome	4.5%
179	Cauda Equina Syndrome	4.5%
180	Posterior Leukoencephalopathy Syndrome	4.5%
181	Posterior reversible encephalopathy syndrome	4.5%
182	Brain Abscess	4.4%
183	Ophthalmoplegia	4.4%
184	External Ophthalmoplegia	4.4%
185	Charcot-Marie-Tooth Disease	4.4%
186	Akinetic Mutism	4.4%
187	Anoxic Encephalopathy	4.4%
188	Arachnoiditis	4.4%
189	Basal Ganglia Diseases	4.4%
190	Brain Damage, Chronic	4.4%
191	Cerebellar Diseases	4.4%
192	Encephalitis	4.4%
193	Encephalomalacia	4.4%
194	Epilepsy	4.4%
195	Hydrocephalus	4.4%
196	Congenital Hydrocephalus	4.4%
197	Hypothalamic Diseases	4.4%
198	Aseptic Meningitis	4.4%
199	Neuritis	4.4%
200	Polyneuritis	4.4%
201	Radiculitis	4.4%
202	Syringomyelia	4.4%
203	Thalamic Diseases	4.4%
204	Intracranial Hypertension	4.4%
205	Polyneuropathy	4.4%
206	Mononeuritis	4.4%
207	Aura	4.4%
208	Leukoencephalopathy	4.4%
209	Essential Tremor	4.4%
210	Neuroaxonal Dystrophies	4.4%
211	Familial Tremor	4.4%
212	Headache Disorders	4.4%
213	Mononeuropathies	4.4%
214	Intracranial Hypotension	4.4%
215	Brachial Plexus Neuropathies	4.4%
216	Radiculopathy	4.4%
217	Mononeuropathy Multiplex	4.4%
218	Nerve Root Compression	4.4%
219	Brain Edema	4.4%
220	Brain Hypoxia	4.4%
221	Aqueductal Stenosis	4.4%
222	Pneumorrhachis	4.4%
223	Writer's Cramp	4.4%
224	Lupus Vasculitis, Central Nervous System	4.4%
225	Vasculitis, Central Nervous System	4.3%
226	Cerebellar Neoplasms	4.3%
227	Marijuana Abuse	4.3%
228	Opioid-Related Disorders	4.3%
229	Nicotine Dependence	4.3%
230	Opioid abuse	4.3%
231	Phencyclidine Abuse	4.3%
232	Substance Abuse, Intravenous	4.3%
233	Substance Withdrawal Syndrome	4.3%
234	Tobacco Use Disorder	4.3%
235	Alcohol-Related Disorders	4.3%
236	Amphetamine-Related Disorders	4.3%
237	Cocaine-Related Disorders	4.3%
238	Metabolic Side Effects of Drugs and Substances	4.3%
239	Jet Lag Syndrome	4.3%
240	Injection Site Reaction	4.2%
241	Infusion site reaction	4.2%
242	Pupil Disorders	4.2%
243	Neurobehavioral Manifestations	4.2%
244	Drug Overdose	4.2%
245	Canavan Disease	4.1%
246	Alexander Disease	4.1%
247	Brain Death	4.1%
248	Coma, Post-Head Injury	4.1%
249	Paraneoplastic Encephalomyelitis	4.1%
250	Dementia, Vascular	4%
251	Myoclonic Epilepsy	4%
252	Epilepsy, Temporal Lobe	4%
253	Epilepsy, Rolandic	4%
254	Benign Rolandic Epilepsy	4%
255	Brain Hemorrhage, Traumatic	4%
256	Uveomeningoencephalitic Syndrome	4%
257	Sturge-Weber Syndrome	4%
258	Vertigo	4%
259	Tuberous Sclerosis	4%
260	Friedreich Ataxia	3.9%
261	Creutzfeldt-Jakob disease	3.9%
262	Basal Ganglia Cerebrovascular Disease	3.9%
263	Ataxia Telangiectasia	3.9%
264	Brain Injuries, Diffuse	3.9%
265	Traumatic Brain Injury	3.9%
266	Cerebellar Ataxia	3.9%
267	Supratentorial Neoplasms	3.9%
268	Torticollis	3.9%
269	Multiple Sclerosis, Chronic Progressive	3.9%
270	Multiple Sclerosis, Relapsing-Remitting	3.9%
271	Amblyopia	3.9%
272	Myotonia Congenita	3.8%
273	Vocal Cord Paralysis	3.8%
274	Paraneoplastic Cerebellar Degeneration	3.8%
275	Cerebrospinal Fluid Otorrhea	3.8%
276	Cerebrospinal Fluid Rhinorrhea	3.8%
277	Neuritis, Autoimmune, Experimental	3.8%
278	Gait Ataxia	3.8%
279	Tuberculosis, Meningeal	3.7%
280	Carotid Artery Injuries	3.7%
281	Juvenile Myoclonic Epilepsy	3.6%
282	Myoclonic Epilepsies, Progressive	3.6%
283	Carpal Tunnel Syndrome	3.6%
284	Vascular Headaches	3.6%
285	neurofibroma	3.6%
286	Hypoxia-Ischemia, Brain	3.6%
287	Sciatica	3.5%
288	Tardive Dyskinesia	3.5%
289	Persistent Vegetative State	3.5%
290	Myotonic Dystrophy	3.5%
291	Neonatal Abstinence Syndrome	3.4%
292	Voice Disorders	3.4%
293	Voice Disturbance	3.4%
294	Hepatolenticular Degeneration	3.4%
295	Brain Diseases, Metabolic	3.4%
296	Cerebrovascular Disorders	3.4%
297	Myositis	3.4%
298	Optic Atrophy	3.4%
299	Optic Neuritis	3.4%
300	Papilledema	3.4%
301	Strabismus	3.4%
302	Tolosa-Hunt Syndrome	3.4%
303	Cerebrovascular Insufficiency	3.4%
304	Isaacs syndrome	3.4%
305	Dementia	3.4%
306	Myotonic Disorders	3.4%
307	Central Nervous System Fungal Infections	3.4%
308	Conus Medullaris Syndrome	3.4%
309	Myasthenic Syndromes, Congenital	3.4%
310	Spinal Cord Vascular Diseases	3.4%
311	Smith-Magenis syndrome	3.4%
312	Dural Arteriovenous Fistula	3.3%
313	Alice in Wonderland Syndrome	3.3%
314	Diabetic Neuropathies	3.3%
315	Facial Injuries	3.3%
316	Facial Neuralgia	3.3%
317	Diabetic Amyotrophy	3.3%
318	Diabetic Autonomic Neuropathy	3.3%
319	Sleep Talking	3.3%
320	Sleep Disorders, Intrinsic	3.3%
321	Orthostatic intolerance	3.3%
322	Alcohol-Induced Disorders	3.3%
323	Anosmia	3.3%
324	Ataxia	3.3%
325	Athetosis	3.3%
326	Catalepsy	3.3%
327	Dystonia	3.3%
328	Hemiplegia	3.3%
329	Leukomalacia, Periventricular	3.3%
330	Locked-In Syndrome	3.3%
331	Meningeal Neoplasms	3.3%
332	Meningomyelocele	3.3%
333	Muscle Hypertonia	3.3%
334	Muscle hypotonia	3.3%
335	Myoclonus	3.3%
336	Myotonia	3.3%
337	Neuralgia	3.3%
338	Paraplegia	3.3%
339	Pseudobulbar Palsy	3.3%
340	Quadriplegia	3.3%
341	Spasm	3.3%
342	Spastic Paraplegia	3.3%
343	Status Epilepticus	3.3%
344	Taste Disorders	3.3%
345	Tremor	3.3%
346	Spina Bifida	3.3%
347	Monoplegia	3.3%
348	Hypokinesia	3.3%
349	Paraparesis	3.3%
350	Bradykinesia	3.3%
351	Waxy flexibility	3.3%
352	Action Tremor	3.3%
353	Resting Tremor	3.3%
354	Dysosmia	3.3%
355	Quadriparesis	3.3%
356	Olfaction Disorders	3.3%
357	Myokymia	3.3%
358	Vestibular Neuronitis	3.3%
359	Somatosensory Disorders	3.3%
360	Neuropathic pain	3.3%
361	Hyperkinesia	3.3%
362	Intention tremor	3.3%
363	Akathisia	3.3%
364	Restlessness	3.3%
365	Psychomotor Agitation	3.3%
366	Cerebral Palsy	3.3%
367	Epilepsies, Partial	3.3%
368	Epilepsy, Generalized	3.3%
369	Pseudotumor Cerebri	3.3%
370	Sciatic Neuropathy	3.3%
371	Hypertensive Encephalopathy	3.3%
372	Ulnar Neuropathies	3.3%
373	Lesion of Sciatic Nerve	3.3%
374	Simple Partial Seizures	3.3%
375	Epilepsy, Reflex	3.3%
376	Ulnar Neuritis	3.3%
377	Radial nerve compression	3.3%
378	Radial Tunnel Syndrome	3.3%
379	Peroneal Neuropathies	3.3%
380	Radial Neuropathy	3.3%
381	Median Neuropathy	3.3%
382	Sciatic Nerve Palsy	3.3%
383	Femoral Neuropathy	3.3%
384	Tibial Neuropathy	3.3%
385	Ulnar Nerve Palsy	3.3%
386	Postural Orthostatic Tachycardia Syndrome	3.3%
387	Radial nerve palsy	3.3%
388	Headache Disorders, Primary	3.3%
389	Headache Disorders, Secondary	3.3%
390	Medication overuse headache	3.3%
391	Brain Concussion	3.2%
392	Cubital Tunnel Syndrome	3.2%
393	Diffuse Axonal Injury	3.2%
394	Brain Stem Neoplasms	3.2%
395	Pituitary Adenoma	3.1%
396	Pituitary Neoplasms	3.1%
397	Optic Nerve Glioma	3.1%
398	Toxoplasmosis, Cerebral	3.1%
399	Vertebral Artery Dissection	3%
400	Amnesia, Transient Global	3%
401	Gait Apraxia	3%
402	Refsum Disease	3%
403	Meningitis, Cryptococcal	3%
404	Meningitis, Listeria	3%
405	Meningitis, Haemophilus	3%
406	Meningitis, Pneumococcal	3%
407	Frontotemporal dementia	3%
408	Basal Ganglia Hemorrhage	2.9%
409	Choroid Plexus Papilloma	2.9%
410	Cardiotoxicity	2.8%
411	Reflex, Abnormal	2.8%
412	Hyporeflexia	2.8%
413	Hyperreflexia	2.8%
414	Alstrom Syndrome	2.8%
415	Wernicke Encephalopathy	2.8%
416	Mitochondrial Encephalomyopathies	2.8%
417	Hand-Arm Vibration Syndrome	2.8%
418	Vision Disorders	2.7%
419	Metamorphopsia	2.7%
420	Visual Impairment	2.7%
421	Pituitary Apoplexy	2.7%
422	Fibromyalgia	2.7%
423	Optic Neuropathy, Ischemic	2.7%
424	Anterior Ischemic Optic Neuropathy	2.7%
425	Central Nervous System Bacterial Infections	2.7%
426	Medial Tibial Stress Syndrome	2.7%
427	Polyradiculopathy	2.7%
428	Post-Traumatic Headache	2.7%
429	Tension Headache	2.7%
430	Epilepsy, Complex Partial	2.7%
431	Migraine Disorders	2.7%
432	Abdominal Migraine	2.7%
433	Status Migrainosus	2.7%
434	Cervicogenic Headache	2.7%
435	Brain Contusion	2.7%
436	Brain Infarction	2.7%
437	Facial Hemiatrophy	2.7%
438	Melkersson-Rosenthal Syndrome	2.7%
439	Mitochondrial Myopathies	2.7%
440	Subarachnoid Hemorrhage, Traumatic	2.7%
441	Carotid Artery, Internal, Dissection	2.7%
442	Anisocoria	2.7%
443	Confusion	2.7%
444	Facial paralysis	2.7%
445	Lethargy	2.7%
446	Memory Disorders	2.7%
447	Muscle Cramp	2.7%
448	Perceptual Disorders	2.7%
449	Psychomotor Disorders	2.7%
450	Tonic Pupil	2.7%
451	Eosinophilia-Myalgia Syndrome	2.7%
452	Anhedonia	2.7%
453	Disorientation	2.7%
454	Facial Paresis	2.7%
455	Memory Loss	2.7%
456	Hemisensory Neglect	2.7%
457	Dysacusis	2.7%
458	Subacute Sclerosing Panencephalitis	2.7%
459	Sleep Bruxism	2.6%
460	Putaminal Hemorrhage	2.6%
461	Anencephaly	2.6%
462	Meningocele	2.6%
463	Muscular Atrophy	2.6%
464	Respiratory Paralysis	2.6%
465	Encephalocele	2.6%
466	Tetany	2.6%
467	Pituitary Diseases	2.6%
468	Infarction, Middle Cerebral Artery	2.6%
469	Infarction, Anterior Cerebral Artery	2.6%
470	Infarction, Posterior Cerebral Artery	2.6%
471	Amyloid Neuropathies, Familial	2.5%
472	Classical Lissencephalies and Subcortical Band Heterotopias	2.5%
473	Thoracic Outlet Syndrome	2.5%
474	Alcohol Use Disorder	2.5%
475	Alcoholic Intoxication	2.5%
476	Heroin Dependence	2.5%
477	Morphine Dependence	2.5%
478	Alcohol abuse	2.5%
479	Adrenoleukodystrophy	2.5%
480	Carotid Artery Diseases	2.5%
481	Brain Ischemia	2.5%
482	Esotropia	2.5%
483	Exotropia	2.5%
484	Hypotension, Orthostatic	2.5%
485	Sleep Apnea Syndromes	2.5%
486	Cerebrovascular accident	2.5%
487	Polymyositis	2.5%
488	Kluver-Bucy Syndrome	2.5%
489	Vasospasm, Intracranial	2.5%
490	Spinal Cord Ischemia	2.5%
491	Intracranial Arterial Diseases	2.5%
492	Post-Exercise Hypotension	2.5%
493	Auditory Perceptual Disorders	2.4%
494	Disorders of Excessive Somnolence	2.4%
495	Sleep Initiation and Maintenance Disorders	2.4%
496	Night Terrors	2.4%
497	Somnambulism	2.4%
498	Trigeminal Nerve Disorder	2.4%
499	Transient Insomnia	2.4%
500	Sleep Paralysis	2.4%
501	Chronic Insomnia	2.4%
502	REM Sleep Behavior Disorder	2.4%
503	Hypersomnia	2.4%
504	Dermal Sinus	2.4%
505	Dysgeusia	2.4%
506	Formication	2.4%
507	Hyperalgesia	2.4%
508	Hyperesthesia	2.4%
509	Hypesthesia	2.4%
510	Language Disorders	2.4%
511	Numbness	2.4%
512	Paresthesia	2.4%
513	Paraparesis, Spastic	2.4%
514	Spina Bifida Cystica	2.4%
515	Trismus	2.4%
516	Spina Bifida Occulta	2.4%
517	Epilepsia Partialis Continua	2.4%
518	Hypogeusia	2.4%
519	Meningeal Carcinomatosis	2.4%
520	Brown-Sequard Syndrome	2.4%
521	Lissencephaly	2.4%
522	Polymicrogyria	2.4%
523	Pachygyria	2.4%
524	Schizencephaly	2.4%
525	Lockjaw	2.4%
526	Allodynia	2.4%
527	Periventricular Nodular Heterotopia	2.4%
528	Ageusia	2.4%
529	Cluster Headache	2.4%
530	Migraine with Aura	2.4%
531	Familial Hemiplegic Migraine	2.4%
532	Chronic Paroxysmal Hemicrania	2.4%
533	SUNCT Syndrome	2.4%
534	Paroxysmal Hemicrania	2.4%
535	Tuberculosis, Central Nervous System	2.4%
536	Cerebral Infarction	2.4%
537	Brain Stem Infarctions	2.4%
538	Acoustic Neuroma	2.4%
539	Giant Cell Arteritis	2.4%
540	Temporal Arteritis	2.4%
541	Alexia	2.3%
542	Dyslexia	2.3%
543	Duane Retraction Syndrome	2.3%
544	Lateral Medullary Syndrome	2.3%
545	Consciousness Disorders	2.2%
546	Mental Retardation	2.2%
547	Muscle Weakness	2.2%
548	Depressed Level of Consciousness	2.2%
549	Mental deficiency	2.2%
550	Intellectual Disability	2.2%
551	Mobius Syndrome	2.2%
552	Bell Palsy	2.2%
553	Catatonia	2.2%
554	Herpes Zoster Oticus	2.2%
555	Familial Periodic Paralysis	2.2%
556	Aphonia	2.2%
557	Sleep Deprivation	2.2%
558	Dysphonia	2.2%
559	MELAS Syndrome	2.2%
560	Moyamoya Disease	2.2%
561	Neurofibrosarcoma	2.2%
562	West Nile Fever	2.1%
563	Hematoma, Subdural	2.1%
564	Hematoma, Epidural, Cranial	2.1%
565	Empty Sella Syndrome	2.1%
566	Hyperpituitarism	2.1%
567	Hypopituitarism	2.1%
568	Hypophysitis	2.1%
569	Eye Injuries	2%
570	Cerebral Arterial Diseases	2%
571	Vertebrobasilar Insufficiency	2%
572	Anterior Spinal Artery Syndrome	2%
573	Basilar Artery Stenosis	2%
574	Vertebral Artery Stenosis	2%
575	Sleep Apnea, Obstructive	2%
576	Sleep Apnea, Central	2%
577	Intracranial Hemorrhage, Hypertensive	2%
578	Transient Cerebral Ischemia	2%
579	Narcolepsy	2%
580	Trigeminal Neuralgia	2%
581	Kleine-Levin Syndrome	2%
582	Kearns-Sayre syndrome	2%
583	Agraphia	2%
584	Anomia	2%
585	Cluttering	2%
586	Language Development Disorders	2%
587	Speech Disorders	2%
588	Syncope	2%
589	Stupor	2%
590	Dysgraphia	2%
591	Presyncope	2%
592	Dyslalia	2%
593	Muscular Dystrophy	2%
594	Congenital nystagmus	2%
595	Orbital Myositis	2%
596	Optic Atrophy, Hereditary, Leber	2%
597	Drug Eruptions	2%
598	Diplopia	2%
599	Muscle Rigidity	2%
600	Muscle Spasticity	2%
601	Scotoma	2%
602	Photophobia	2%
603	Cogwheel Rigidity	2%
604	Hemifacial Spasm	2%
605	Amaurosis	2%
606	Blindness	2%
607	Nuchal Rigidity	2%
608	Reye Syndrome	2%
609	Binge Drinking	2%
610	Neuroaspergillosis	2%
611	Pyomyositis	2%
612	Intracranial Embolism and Thrombosis	2%
613	Hepatic Encephalopathy	2%
614	Agnosia	2%
615	Apraxias	2%
616	Hallucinations	2%
617	Hemianopsia	2%
618	Hyperacusis	2%
619	Tinnitus	2%
620	Visual Agnosia	2%
621	Anosognosia	2%
622	Wernicke-Korsakoff Syndrome	2%
623	Phonophobia	2%
624	Hearing Loss	2%
625	Sarcopenia	1.9%
626	Myalgia	1.9%
627	Neuronal Ceroid-Lipofuscinoses	1.9%
628	Hematoma, Subdural, Intracranial	1.8%
629	Hematoma, Subdural, Chronic	1.8%
630	Hematoma, Subdural, Acute	1.8%
631	Hyperprolactinemia	1.8%
632	Subclavian Steal Syndrome	1.8%
633	Pick Disease of the Brain	1.8%
634	Cataplexy	1.8%
635	Aphasia	1.8%
636	Articulation Disorders	1.8%
637	Echolalia	1.8%
638	Stuttering	1.8%
639	Dysphasia	1.8%
640	Pseudorabies	1.7%
641	Dysarthria	1.7%
642	Aicardi's syndrome	1.7%
643	Hoarseness	1.7%
644	Amnesia	1.7%
645	Cockayne Syndrome	1.7%
646	Delirium	1.7%
647	Dissociative Amnesia	1.7%
648	Color blindness	1.7%
649	Global Amnesia	1.7%
650	Toxoplasmosis, Congenital	1.7%
651	Cri-du-Chat Syndrome	1.6%
652	Down Syndrome	1.6%
653	Brain Diseases, Metabolic, Inborn	1.6%
654	Trisomy 21	1.6%
655	Eye Burns	1.6%
656	Cardiomyopathy, Alcoholic	1.6%
657	Malaria, Cerebral	1.6%
658	POEMS Syndrome	1.6%
659	Pancreatitis, Alcoholic	1.6%
660	Meningioma	1.6%
661	Williams Syndrome	1.6%
662	Carotid Stenosis	1.6%
663	Intracranial Aneurysm	1.6%
664	Welander Distal Myopathy	1.6%
665	Microcephaly	1.6%
666	Macrocephaly	1.6%
667	Neurocysticercosis	1.6%
668	Neurosyphilis	1.6%
669	Hypokalemic periodic paralysis	1.6%
670	Amaurosis Fugax	1.6%
671	Blindness, Cortical	1.6%
672	Dyscalculia	1.6%
673	Intracranial Arteriosclerosis	1.6%
674	Cerebral Atherosclerosis	1.6%
675	Rett Syndrome	1.6%
676	Subarachnoid Hemorrhage	1.6%
677	Cerebral Arteriosclerosis	1.6%
678	Cerebral Hemorrhage	1.6%
679	Cerebral Thrombosis	1.6%
680	Intracranial Embolism	1.6%
681	Intracranial Thrombosis	1.6%
682	Porencephaly	1.6%
683	Deafness	1.6%
684	Hearing Loss, Sudden	1.6%
685	Gerstmann Syndrome	1.6%
686	Hearing Loss, Bilateral	1.6%
687	Hearing Loss, High-Frequency	1.6%
688	Hearing Loss, Mixed Conductive-Sensorineural	1.6%
689	Prosopagnosia	1.6%
690	Apraxia, Ideomotor	1.6%
691	Charles Bonnet Syndrome	1.6%
692	Hearing Loss, Unilateral	1.6%
693	Complete Hearing Loss	1.6%
694	Alien Hand Syndrome	1.6%
695	Deaf Mutism	1.6%
696	Mutism	1.5%
697	Selective Mutism	1.5%
698	Acromegaly	1.5%
699	Holoprosencephaly	1.5%
700	Cerebral Amyloid Angiopathy	1.4%
701	Sinus Thrombosis, Intracranial	1.4%
702	Asthma, Aspirin-Induced	1.4%
703	Prader-Willi Syndrome	1.4%
704	AIDS Dementia Complex	1.4%
705	Waterhouse-Friderichsen Syndrome	1.4%
706	Dermatomyositis	1.4%
707	Corneal Scar	1.4%
708	Phantom pain	1.4%
709	Phantom Limb Pain	1.4%
710	Lyme Neuroborreliosis	1.4%
711	Alexia, Pure	1.4%
712	Muscular Dystrophy, Duchenne	1.4%
713	Cavernous Sinus Thrombosis	1.4%
714	Sagittal Sinus Thrombosis	1.4%
715	Retrograde amnesia	1.3%
716	Amnesia, Anterograde	1.3%
717	Menkes Kinky Hair Syndrome	1.3%
718	Carotid Artery Thrombosis	1.3%
719	Fetal Alcohol Spectrum Disorders	1.3%
720	Acute Generalized Exanthematous Pustulosis	1.3%
721	Kernicterus	1.3%
722	Corneal Perforation	1.2%
723	Fragile X Syndrome	1.2%
724	Nelson Syndrome	1.1%
725	Rubinstein-Taybi Syndrome	1.1%
726	Erythema Nodosum	1.1%
727	Serum Sickness	1.1%
728	Fabry Disease	1.1%
729	Prolactinoma	1%
730	Growth Hormone-Secreting Pituitary Adenoma	1%
731	Galactosemias	1%
732	Urea Cycle Disorders, Inborn	1%
733	Tyrosinemias	1%
734	Fatty Liver, Alcoholic	1%
735	Hepatitis, Alcoholic	1%
736	Liver Cirrhosis, Alcoholic	1%
737	Homocystinuria	0.9%
738	Leigh Disease	0.9%
739	Toxic Epidermal Necrolysis	0.8%
740	Stevens-Johnson Syndrome	0.8%
741	Carbamoyl-Phosphate Synthase I Deficiency Disease	0.8%
742	Mucopolysaccharidosis II	0.8%
743	Glycogen storage disease type II	0.7%
744	Zellweger Syndrome	0.7%
745	Gaucher Disease	0.6%
746	Tay-Sachs Disease	0.6%
747	Niemann-Pick Disease, Type C	0.5%

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