MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Tarsal Tunnel Syndrome

(UMLS:C0039319)

Definition:: Entrapment of the distal branches of the posterior TIBIAL NERVE (which divides into the medial plantar, lateral plantar, and calcanial nerves) in the tarsal tunnel, which lies posterior to the internal malleolus and beneath the retinaculum of the flexor muscles of the foot. Symptoms include ankle pain radiating into the foot which tends to be aggravated by walking. Examination may reveal Tinel's sign (radiating pain following nerve percussion) over the tibial nerve at the ankle, weakness and atrophy of the small foot muscles, or loss of sensation in the foot. (From Foot Ankle 1990;11(1):47-52)
UMLS ID:: C0039319
MeSH ID:: D013641

Classification:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.668.829.500.700.800|C10.668.829.550.800

Synonym(s)

Tarsal Tunnel Syndrome

TTS - Tarsal tunnel syndrome

Tarsal tunnel syndrome

Tarsal tunnel syndrome (ankle condition)

Tarsal tunnel syndrome, unspecified lower limb

compression; posterior tibial nerve (in tarsal tunnel)

entrapment; neuropathic, nerve, posterior tibial

syndrome tarsal tunnel

syndrome; tarsal tunnel

10.

tarsal tunnel syndrome

11.

tarsal tunnel; syndrome

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Ciprofloxacin	FAERS: 9	US FAERS
2	Levofloxacin	FAERS: 6	US FAERS
3	Pregabalin	FAERS: 4	US FAERS
4	rofecoxib	FAERS: 4	OFFSIDES US FAERS
5	Latanoprost	FAERS: 2	OFFSIDES US FAERS
6	Thyroxine	FAERS: 2	US FAERS
7	4-hydroxybutyric acid	FAERS: 1	US FAERS
8	Atorvastatin	FAERS: 1	US FAERS
9	Duloxetine Hydrochloride	FAERS: 1	US FAERS
10	Raloxifene Hydrochloride	FAERS: 1	US FAERS
11	Testosterone	FAERS: 1	US FAERS
12	Trimethoprim, Sulfamethoxazole Drug Combination	FAERS: 1	US FAERS
13	naloxegol	FAERS: 1	US FAERS
14	Anastrozole		OFFSIDES
15	Bupropion		OFFSIDES
16	Clarithromycin		OFFSIDES
17	Clotrimazole		OFFSIDES
18	Econazole		OFFSIDES
19	Erythromycin		OFFSIDES
20	Estrogens, Conjugated (USP)		OFFSIDES
21	Etodolac		OFFSIDES
22	Fluconazole		OFFSIDES
23	Flunitrazepam		OFFSIDES
24	Ketoconazole		OFFSIDES
25	Meloxicam		OFFSIDES
26	Mercaptopurine		OFFSIDES
27	Mometasone Furoate		OFFSIDES
28	Mupirocin		OFFSIDES
29	Nortriptyline		OFFSIDES
30	Olmesartan Medoxomil		OFFSIDES
31	Oseltamivir		OFFSIDES
32	Phenprocoumon		OFFSIDES
33	Quinidine		OFFSIDES
34	Salmeterol Xinafoate		OFFSIDES
35	Torsemide		OFFSIDES
36	bucindolol		OFFSIDES
37	rizatriptan		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Cauda Equina Syndrome	46.4%
2	Carpal Tunnel Syndrome	42.6%
3	Neuritis	41.6%
4	Polyneuritis	41.6%
5	Radiculitis	41.6%
6	Polyneuropathy	41.6%
7	Brachial Plexus Neuropathies	41.6%
8	Radiculopathy	41.6%
9	Nerve Root Compression	41.6%
10	Complex Regional Pain Syndromes	39.8%
11	Brachial Plexus Neuritis	39.4%
12	Neuralgic Amyotrophy	39.4%
13	Sciatic Neuropathy	39%
14	Ulnar Neuropathies	39%
15	Lesion of Sciatic Nerve	39%
16	Ulnar Neuritis	39%
17	Radial nerve compression	39%
18	Radial Tunnel Syndrome	39%
19	Peroneal Neuropathies	39%
20	Radial Neuropathy	39%
21	Median Neuropathy	39%
22	Sciatic Nerve Palsy	39%
23	Femoral Neuropathy	39%
24	Ulnar Nerve Palsy	39%
25	Radial nerve palsy	39%
26	Causalgia	35.3%
27	Cubital Tunnel Syndrome	35.1%
28	Thoracic Outlet Syndrome	33.3%
29	Peripheral Nerve Injuries	32.3%
30	Motor Neuron Disease	32.1%
31	Isaacs syndrome	32%
32	Sciatica	31.9%
33	Neuromuscular Junction Diseases	31.5%
34	Diabetic Neuropathies	31.4%
35	Diabetic Amyotrophy	31.4%
36	Diabetic Autonomic Neuropathy	31.4%
37	Neuralgia	31.2%
38	Neuropathic pain	31.2%
39	Guillain-Barre Syndrome	31.2%
40	Acrodynia	27.1%
41	Hand-Arm Vibration Syndrome	26.6%
42	Myopathy	24.9%
43	Stiff-Person Syndrome	24.4%
44	Reflex Sympathetic Dystrophy	24.3%
45	Polyradiculoneuropathy	24.2%
46	Polyradiculoneuritis	24.2%
47	Mononeuritis	22.7%
48	Mononeuropathies	22.7%
49	Mononeuropathy Multiplex	22.7%
50	Cranial nerve diseases	20.2%
51	Demyelinating Diseases	20.2%
52	Demyelination	20.2%
53	Chronobiology Disorders	20.2%
54	Chronic Fatigue Syndrome	19.7%
55	Poliomyelitis	19.3%
56	Polyradiculopathy	18.6%
57	Spinal Muscular Atrophy	18%
58	Progressive Muscular Atrophy	18%
59	Progressive bulbar palsy	18%
60	Bulbar palsy	18%
61	Miller Fisher Syndrome	17.7%
62	Myasthenia Gravis	17.3%
63	Tarsal Tunnel Syndrome	16.8%
64	Neuritis, Autoimmune, Experimental	16.2%
65	Trauma, Nervous System	15.8%
66	Amyotrophic Lateral Sclerosis	15.5%
67	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	15.4%
68	Nervous System Neoplasms	15.3%
69	Neurologic Manifestations	15.3%
70	Neurotoxicity Syndromes	15.3%
71	Tibial Neuropathy	15%
72	Botulism	14.3%
73	Myositis	13.7%
74	Myotonic Disorders	13.7%
75	Myasthenic Syndromes, Congenital	13.7%
76	neurofibroma	13.5%
77	Ocular Motility Disorders	13.3%
78	Cyclophoria	13.3%
79	POEMS Syndrome	13.3%
80	Multiple System Atrophy	13.2%
81	Lambert-Eaton Myasthenic Syndrome	13%
82	Restless Legs Syndrome	12.7%
83	Sleep Wake Disorders	12.5%
84	Encephalomyelitis	12.4%
85	Prion Diseases	12.4%
86	Autonomic Dysreflexia	12.4%
87	Charcot-Marie-Tooth Disease	12.2%
88	Subacute Combined Degeneration	11.6%
89	Fibromyalgia	11.1%
90	Medial Tibial Stress Syndrome	11.1%
91	Mitochondrial Myopathies	11%
92	Eosinophilia-Myalgia Syndrome	10.9%
93	Amyloid Neuropathies, Familial	10.8%
94	Marchiafava-Bignami Disease	10.7%
95	Brain Diseases	10.5%
96	Dysautonomia	10.5%
97	Meningitis	10.5%
98	Movement Disorders	10.5%
99	Pachymeningitis	10.5%
100	Spinal Cord Diseases	10.5%
101	Vagus Nerve Disorder	10.5%
102	Glossopharyngeal Neuralgia	10.5%
103	Abducens Nerve Diseases	10.5%
104	Heavy Metal Poisoning, Nervous System	10.5%
105	Tauopathies	10.5%
106	Trochlear Nerve Diseases	10.5%
107	Spinal Cord Injuries	10.4%
108	Ophthalmoplegic Migraine	10.2%
109	Parkinson Disease	10.1%
110	Asterixis	10%
111	Ballismus	10%
112	Meningoencephalitis	9.8%
113	Dandy-Walker Syndrome	9%
114	Familial Periodic Paralysis	9%
115	Pneumocephalus	9%
116	Myelitis	9%
117	Lewy Body Disease	8.9%
118	Myasthenia Gravis, Autoimmune, Experimental	8.7%
119	Myotonia Congenita	8.7%
120	Sleep Disorders, Circadian Rhythm	8.6%
121	Neuroleptic Malignant Syndrome	8.6%
122	Myelinolysis, Central Pontine	8.6%
123	Myotonic Dystrophy	8.5%
124	Polymyositis	8.5%
125	Central Nervous System Infection	8.3%
126	Optic Neuropathy	8.3%
127	Central Nervous System Cysts	8.3%
128	Striatonigral Degeneration	8.1%
129	Facial Nerve Diseases	8%
130	Craniocerebral Trauma	8%
131	Parasomnia	8%
132	Dyssomnias	8%
133	Vestibulocochlear Nerve Diseases	7.9%
134	Decerebrate State	7.9%
135	Hemiparesis	7.9%
136	Hydranencephaly	7.9%
137	Meningism	7.9%
138	Neural Tube Defects	7.9%
139	Paresis	7.9%
140	Seizures	7.9%
141	Sensation Disorders	7.9%
142	Tethered Cord Syndrome	7.9%
143	Central Nervous System Neoplasms	7.9%
144	Complex partial seizures	7.9%
145	Iniencephaly	7.9%
146	Craniorachischisis	7.9%
147	Exencephaly	7.9%
148	Monoparesis	7.9%
149	Septo-Optic Dysplasia	7.9%
150	Cortical Dysplasia	7.9%
151	Neurogenic Inflammation	7.9%
152	Gait Disorders, Neurologic	7.9%
153	Neuromuscular Manifestations	7.9%
154	Malformations of Cortical Development	7.9%
155	Epidural Abscess	7.9%
156	Olfactory Nerve Injuries	7.9%
157	Sweating, Gustatory	7.8%
158	Auriculotemporal Syndrome	7.8%
159	Alstrom Syndrome	7.8%
160	Progressive supranuclear palsy	7.8%
161	Myalgia	7.7%
162	Dyskinesia, Drug-Induced	7.7%
163	Myelitis, Transverse	7.7%
164	MPTP Poisoning	7.6%
165	Neurofibrosarcoma	7.5%
166	Opsoclonus-Myoclonus Syndrome	7.3%
167	Encephalomyelitis, Acute Disseminated	7.3%
168	Subdural Effusion	7.3%
169	Parkinsonian Disorders	7.3%
170	Nocturnal Myoclonus Syndrome	7.3%
171	Leukoencephalitis, Acute Hemorrhagic	7.3%
172	Brain Injuries	7.2%
173	Refsum Disease	7.2%
174	Brain Neoplasms	7.2%
175	Multiple Sclerosis	7.2%
176	Spinal Cord Neoplasms	7.2%
177	Akathisia, Drug-Induced	7.1%
178	Horner Syndrome	7.1%
179	Neuromyelitis Optica	7%
180	Shy-Drager Syndrome	6.9%
181	Muscular Dystrophy	6.9%
182	Orbital Myositis	6.9%
183	Pyomyositis	6.8%
184	Dystonia Musculorum Deformans	6.8%
185	Facial Nerve Injuries	6.8%
186	Pupil Disorders	6.6%
187	Neurobehavioral Manifestations	6.6%
188	Mitochondrial Encephalomyopathies	6.5%
189	Paraneoplastic Encephalomyelitis	6.4%
190	Uveomeningoencephalitic Syndrome	6.3%
191	Sturge-Weber Syndrome	6.3%
192	Vertigo	6.3%
193	Alcohol-Induced Disorders, Nervous System	6.3%
194	Vasculitis, Central Nervous System	6.1%
195	Jet Lag Syndrome	6.1%
196	Brain Abscess	6.1%
197	Ophthalmoplegia	6.1%
198	External Ophthalmoplegia	6.1%
199	Leukoencephalopathy, Progressive Multifocal	6%
200	Akinetic Mutism	5.9%
201	Anoxic Encephalopathy	5.9%
202	Arachnoiditis	5.9%
203	Basal Ganglia Diseases	5.9%
204	Brain Damage, Chronic	5.9%
205	Cerebellar Diseases	5.9%
206	Encephalitis	5.9%
207	Encephalomalacia	5.9%
208	Epilepsy	5.9%
209	Hydrocephalus	5.9%
210	Congenital Hydrocephalus	5.9%
211	Hypothalamic Diseases	5.9%
212	Aseptic Meningitis	5.9%
213	Syringomyelia	5.9%
214	Thalamic Diseases	5.9%
215	Intracranial Hypertension	5.9%
216	Aura	5.9%
217	Leukoencephalopathy	5.9%
218	Essential Tremor	5.9%
219	Neuroaxonal Dystrophies	5.9%
220	Familial Tremor	5.9%
221	Headache Disorders	5.9%
222	Intracranial Hypotension	5.9%
223	Brain Edema	5.9%
224	Brain Hypoxia	5.9%
225	Aqueductal Stenosis	5.9%
226	Pneumorrhachis	5.9%
227	Writer's Cramp	5.9%
228	Scrapie	5.9%
229	Central Cord Syndrome	5.9%
230	Presenile dementia	5.9%
231	Senile dementia	5.9%
232	Meningitis, Bacterial	5.9%
233	Meningitis, Fungal	5.9%
234	Chorea	5.8%
235	Limbic Encephalitis	5.8%
236	Tuberous Sclerosis	5.7%
237	Epilepsy, Post-Traumatic	5.6%
238	Hypokalemic periodic paralysis	5.6%
239	Meige Syndrome	5.6%
240	Cerebral Ventriculitis	5.6%
241	Huntington Disease	5.4%
242	Voice Disorders	5.4%
243	Voice Disturbance	5.4%
244	Smith-Magenis syndrome	5.3%
245	Vocal Cord Paralysis	5.3%
246	Dural Arteriovenous Fistula	5.2%
247	Ataxia Telangiectasia	5%
248	Canavan Disease	5%
249	Alexander Disease	5%
250	Lupus Vasculitis, Central Nervous System	5%
251	Amblyopia	4.9%
252	Paraneoplastic Cerebellar Degeneration	4.9%
253	Brain Death	4.9%
254	Coma, Post-Head Injury	4.9%
255	Cerebrospinal Fluid Otorrhea	4.9%
256	Cerebrospinal Fluid Rhinorrhea	4.9%
257	Welander Distal Myopathy	4.8%
258	Gait Ataxia	4.8%
259	Lafora Disease	4.8%
260	Unverricht-Lundborg Syndrome	4.8%
261	Posterior Leukoencephalopathy Syndrome	4.8%
262	Posterior reversible encephalopathy syndrome	4.8%
263	Brain Diseases, Metabolic	4.6%
264	Cerebrovascular Disorders	4.6%
265	Optic Atrophy	4.6%
266	Optic Neuritis	4.6%
267	Papilledema	4.6%
268	Strabismus	4.6%
269	Tolosa-Hunt Syndrome	4.6%
270	Cerebrovascular Insufficiency	4.6%
271	Arsenic Poisoning	4.6%
272	Dementia	4.6%
273	Central Nervous System Fungal Infections	4.6%
274	Conus Medullaris Syndrome	4.6%
275	Spinal Cord Vascular Diseases	4.6%
276	Creutzfeldt-Jakob disease	4.5%
277	Basal Ganglia Cerebrovascular Disease	4.5%
278	Cerebellar Neoplasms	4.5%
279	Brain Injuries, Diffuse	4.5%
280	Traumatic Brain Injury	4.5%
281	Facial Injuries	4.5%
282	Facial Neuralgia	4.5%
283	Sleep Talking	4.5%
284	Manganese Poisoning	4.5%
285	Sleep Disorders, Intrinsic	4.5%
286	Orthostatic intolerance	4.5%
287	Cerebellar Ataxia	4.5%
288	Supratentorial Neoplasms	4.5%
289	Torticollis	4.5%
290	Multiple Sclerosis, Chronic Progressive	4.5%
291	Multiple Sclerosis, Relapsing-Remitting	4.5%
292	Alcohol Withdrawal Seizures	4.5%
293	Dementia, Vascular	4.5%
294	Anosmia	4.5%
295	Ataxia	4.5%
296	Athetosis	4.5%
297	Catalepsy	4.5%
298	Dystonia	4.5%
299	Hemiplegia	4.5%
300	Locked-In Syndrome	4.5%
301	Meningeal Neoplasms	4.5%
302	Meningomyelocele	4.5%
303	Muscle Hypertonia	4.5%
304	Muscle hypotonia	4.5%
305	Myoclonus	4.5%
306	Myotonia	4.5%
307	Paraplegia	4.5%
308	Pseudobulbar Palsy	4.5%
309	Quadriplegia	4.5%
310	Spasm	4.5%
311	Spastic Paraplegia	4.5%
312	Status Epilepticus	4.5%
313	Taste Disorders	4.5%
314	Tremor	4.5%
315	Spina Bifida	4.5%
316	Monoplegia	4.5%
317	Hypokinesia	4.5%
318	Paraparesis	4.5%
319	Bradykinesia	4.5%
320	Waxy flexibility	4.5%
321	Action Tremor	4.5%
322	Resting Tremor	4.5%
323	Dysosmia	4.5%
324	Quadriparesis	4.5%
325	Mercury Poisoning, Nervous System	4.5%
326	Olfaction Disorders	4.5%
327	Myokymia	4.5%
328	Lead Poisoning, Nervous System	4.5%
329	Vestibular Neuronitis	4.5%
330	Somatosensory Disorders	4.5%
331	Hyperkinesia	4.5%
332	Intention tremor	4.5%
333	Brain Hemorrhage, Traumatic	4.5%
334	Reflex, Abnormal	4.4%
335	Hyporeflexia	4.4%
336	Hyperreflexia	4.4%
337	Friedreich Ataxia	4.4%
338	Hepatolenticular Degeneration	4.3%
339	Carotid Artery Injuries	4.2%
340	Akathisia	4.2%
341	Restlessness	4.2%
342	Psychomotor Agitation	4.2%
343	Dermatomyositis	4.1%
344	Muscular Dystrophy, Duchenne	4.1%
345	Myoclonic Epilepsy	4%
346	Epilepsy, Temporal Lobe	4%
347	Epilepsy, Rolandic	4%
348	Benign Rolandic Epilepsy	4%
349	Tuberculosis, Meningeal	3.9%
350	Vascular Headaches	3.9%
351	Hypoxia-Ischemia, Brain	3.8%
352	Tardive Dyskinesia	3.8%
353	Persistent Vegetative State	3.8%
354	Leukomalacia, Periventricular	3.8%
355	Cerebral Palsy	3.7%
356	Epilepsies, Partial	3.7%
357	Epilepsy, Generalized	3.7%
358	Pseudotumor Cerebri	3.7%
359	Hypertensive Encephalopathy	3.7%
360	Simple Partial Seizures	3.7%
361	Epilepsy, Reflex	3.7%
362	Postural Orthostatic Tachycardia Syndrome	3.7%
363	Headache Disorders, Primary	3.7%
364	Headache Disorders, Secondary	3.7%
365	Medication overuse headache	3.7%
366	Vision Disorders	3.7%
367	Metamorphopsia	3.7%
368	Visual Impairment	3.7%
369	Optic Neuropathy, Ischemic	3.7%
370	Vertebral Artery Dissection	3.7%
371	Anterior Ischemic Optic Neuropathy	3.7%
372	Central Nervous System Bacterial Infections	3.7%
373	Amnesia, Transient Global	3.7%
374	Gait Apraxia	3.7%
375	Facial Hemiatrophy	3.7%
376	Melkersson-Rosenthal Syndrome	3.7%
377	MELAS Syndrome	3.6%
378	Anisocoria	3.6%
379	Confusion	3.6%
380	Facial paralysis	3.6%
381	Lethargy	3.6%
382	Memory Disorders	3.6%
383	Muscle Cramp	3.6%
384	Perceptual Disorders	3.6%
385	Psychomotor Disorders	3.6%
386	Tonic Pupil	3.6%
387	Anhedonia	3.6%
388	Disorientation	3.6%
389	Facial Paresis	3.6%
390	Memory Loss	3.6%
391	Hemisensory Neglect	3.6%
392	Dysacusis	3.6%
393	Alice in Wonderland Syndrome	3.6%
394	Sleep Bruxism	3.6%
395	Anencephaly	3.6%
396	Meningocele	3.6%
397	Muscular Atrophy	3.6%
398	Respiratory Paralysis	3.6%
399	Encephalocele	3.6%
400	Tetany	3.6%
401	Optic Nerve Glioma	3.5%
402	Brain Concussion	3.4%
403	Toxoplasmosis, Cerebral	3.4%
404	Kearns-Sayre syndrome	3.3%
405	Acoustic Neuroma	3.2%
406	Meningitis, Cryptococcal	3.2%
407	Meningitis, Listeria	3.2%
408	Meningitis, Haemophilus	3.2%
409	Meningitis, Pneumococcal	3.2%
410	Frontotemporal dementia	3.2%
411	Diffuse Axonal Injury	3.2%
412	Brain Stem Neoplasms	3.2%
413	Juvenile Myoclonic Epilepsy	3.2%
414	Myoclonic Epilepsies, Progressive	3.2%
415	Duane Retraction Syndrome	3.1%
416	Consciousness Disorders	3.1%
417	Mental Retardation	3.1%
418	Muscle Weakness	3.1%
419	Depressed Level of Consciousness	3.1%
420	Mental deficiency	3.1%
421	Intellectual Disability	3.1%
422	Mobius Syndrome	3%
423	Bell Palsy	3%
424	Catatonia	3%
425	Herpes Zoster Oticus	3%
426	Aphonia	3%
427	Sleep Deprivation	3%
428	Dysphonia	3%
429	Pituitary Diseases	3%
430	Pituitary Adenoma	2.9%
431	Pituitary Neoplasms	2.9%
432	Giant Cell Arteritis	2.9%
433	Temporal Arteritis	2.9%
434	Auditory Perceptual Disorders	2.8%
435	Carotid Artery Diseases	2.8%
436	Brain Ischemia	2.8%
437	Esotropia	2.8%
438	Exotropia	2.8%
439	Hypotension, Orthostatic	2.8%
440	Sleep Apnea Syndromes	2.8%
441	Cerebrovascular accident	2.8%
442	Kluver-Bucy Syndrome	2.8%
443	Vasospasm, Intracranial	2.8%
444	Spinal Cord Ischemia	2.8%
445	Intracranial Arterial Diseases	2.8%
446	Post-Exercise Hypotension	2.8%
447	Disorders of Excessive Somnolence	2.8%
448	Sleep Initiation and Maintenance Disorders	2.8%
449	Night Terrors	2.8%
450	Somnambulism	2.8%
451	Trigeminal Nerve Disorder	2.8%
452	Transient Insomnia	2.8%
453	Sleep Paralysis	2.8%
454	Chronic Insomnia	2.8%
455	REM Sleep Behavior Disorder	2.8%
456	Hypersomnia	2.8%
457	Dermal Sinus	2.8%
458	Dysgeusia	2.8%
459	Formication	2.8%
460	Hyperalgesia	2.8%
461	Hyperesthesia	2.8%
462	Hypesthesia	2.8%
463	Language Disorders	2.8%
464	Numbness	2.8%
465	Paresthesia	2.8%
466	Paraparesis, Spastic	2.8%
467	Spina Bifida Cystica	2.8%
468	Trismus	2.8%
469	Spina Bifida Occulta	2.8%
470	Epilepsia Partialis Continua	2.8%
471	Hypogeusia	2.8%
472	Meningeal Carcinomatosis	2.8%
473	Brown-Sequard Syndrome	2.8%
474	Lissencephaly	2.8%
475	Polymicrogyria	2.8%
476	Pachygyria	2.8%
477	Schizencephaly	2.8%
478	Lockjaw	2.8%
479	Allodynia	2.8%
480	Lead Poisoning, Nervous System, Childhood	2.8%
481	Lead Poisoning, Nervous System, Adult	2.8%
482	Periventricular Nodular Heterotopia	2.8%
483	Ageusia	2.8%
484	Tuberculosis, Central Nervous System	2.8%
485	Basal Ganglia Hemorrhage	2.8%
486	Classical Lissencephalies and Subcortical Band Heterotopias	2.7%
487	Pituitary Apoplexy	2.7%
488	Adrenoleukodystrophy	2.7%
489	Brain Contusion	2.7%
490	Brain Infarction	2.7%
491	Post-Traumatic Headache	2.7%
492	Tension Headache	2.7%
493	Epilepsy, Complex Partial	2.7%
494	Migraine Disorders	2.7%
495	Abdominal Migraine	2.7%
496	Status Migrainosus	2.7%
497	Cervicogenic Headache	2.7%
498	Subarachnoid Hemorrhage, Traumatic	2.7%
499	Carotid Artery, Internal, Dissection	2.7%
500	Subacute Sclerosing Panencephalitis	2.5%
501	Neuronal Ceroid-Lipofuscinoses	2.5%
502	Choroid Plexus Papilloma	2.5%
503	Eye Injuries	2.4%
504	Congenital nystagmus	2.3%
505	Aicardi's syndrome	2.3%
506	Diplopia	2.3%
507	Muscle Rigidity	2.3%
508	Muscle Spasticity	2.3%
509	Scotoma	2.3%
510	Photophobia	2.3%
511	Cogwheel Rigidity	2.3%
512	Hemifacial Spasm	2.3%
513	Amaurosis	2.3%
514	Blindness	2.3%
515	Nuchal Rigidity	2.3%
516	Alexia	2.3%
517	Dyslexia	2.3%
518	Reye Syndrome	2.3%
519	Neuroaspergillosis	2.3%
520	Hoarseness	2.3%
521	Putaminal Hemorrhage	2.3%
522	Intracranial Embolism and Thrombosis	2.3%
523	Hepatic Encephalopathy	2.3%
524	Cockayne Syndrome	2.3%
525	Agnosia	2.3%
526	Apraxias	2.3%
527	Hallucinations	2.3%
528	Hemianopsia	2.3%
529	Hyperacusis	2.3%
530	Tinnitus	2.3%
531	Visual Agnosia	2.3%
532	Anosognosia	2.3%
533	Wernicke-Korsakoff Syndrome	2.3%
534	Phonophobia	2.3%
535	Hearing Loss	2.3%
536	Alcohol Withdrawal Delirium	2.2%
537	Sarcopenia	2.2%
538	Hematoma, Subdural	2.2%
539	Hematoma, Epidural, Cranial	2.2%
540	Infarction, Middle Cerebral Artery	2.2%
541	Infarction, Anterior Cerebral Artery	2.2%
542	Infarction, Posterior Cerebral Artery	2.2%
543	Optic Atrophy, Hereditary, Leber	2.2%
544	Cluster Headache	2.1%
545	Migraine with Aura	2.1%
546	Familial Hemiplegic Migraine	2.1%
547	Chronic Paroxysmal Hemicrania	2.1%
548	SUNCT Syndrome	2.1%
549	Paroxysmal Hemicrania	2.1%
550	Cerebral Infarction	2.1%
551	Brain Stem Infarctions	2.1%
552	Moyamoya Disease	2.1%
553	Empty Sella Syndrome	2%
554	Hyperpituitarism	2%
555	Hypopituitarism	2%
556	Hypophysitis	2%
557	Holoprosencephaly	2%
558	Cerebral Arterial Diseases	2%
559	Vertebrobasilar Insufficiency	2%
560	Anterior Spinal Artery Syndrome	2%
561	Basilar Artery Stenosis	2%
562	Vertebral Artery Stenosis	2%
563	Sleep Apnea, Obstructive	2%
564	Sleep Apnea, Central	2%
565	Intracranial Hemorrhage, Hypertensive	2%
566	Transient Cerebral Ischemia	2%
567	Pseudorabies	2%
568	Narcolepsy	2%
569	Trigeminal Neuralgia	2%
570	Kleine-Levin Syndrome	2%
571	Agraphia	2%
572	Anomia	2%
573	Cluttering	2%
574	Language Development Disorders	2%
575	Speech Disorders	2%
576	Syncope	2%
577	Stupor	2%
578	Dysgraphia	2%
579	Presyncope	2%
580	Dyslalia	2%
581	Amnesia	1.9%
582	Delirium	1.9%
583	Dissociative Amnesia	1.9%
584	Color blindness	1.9%
585	Global Amnesia	1.9%
586	Cri-du-Chat Syndrome	1.9%
587	Down Syndrome	1.9%
588	Brain Diseases, Metabolic, Inborn	1.9%
589	Trisomy 21	1.9%
590	Meningioma	1.9%
591	Williams Syndrome	1.9%
592	Microcephaly	1.9%
593	Macrocephaly	1.9%
594	Neurosyphilis	1.9%
595	Porencephaly	1.9%
596	West Nile Fever	1.9%
597	Lateral Medullary Syndrome	1.8%
598	Hematoma, Subdural, Intracranial	1.7%
599	Hematoma, Subdural, Chronic	1.7%
600	Hematoma, Subdural, Acute	1.7%
601	Toxoplasmosis, Congenital	1.6%
602	Prader-Willi Syndrome	1.6%
603	Eye Burns	1.6%
604	Wernicke Encephalopathy	1.6%
605	Malaria, Cerebral	1.6%
606	AIDS Dementia Complex	1.6%
607	Carotid Stenosis	1.6%
608	Intracranial Aneurysm	1.6%
609	Hyperprolactinemia	1.6%
610	Phantom pain	1.6%
611	Phantom Limb Pain	1.6%
612	Neurocysticercosis	1.6%
613	Lyme Neuroborreliosis	1.6%
614	Amaurosis Fugax	1.6%
615	Blindness, Cortical	1.6%
616	Dyscalculia	1.6%
617	Intracranial Arteriosclerosis	1.6%
618	Cerebral Atherosclerosis	1.6%
619	Rett Syndrome	1.6%
620	Subarachnoid Hemorrhage	1.6%
621	Cerebral Arteriosclerosis	1.6%
622	Cerebral Hemorrhage	1.6%
623	Cerebral Thrombosis	1.6%
624	Intracranial Embolism	1.6%
625	Intracranial Thrombosis	1.6%
626	Deafness	1.6%
627	Hearing Loss, Sudden	1.6%
628	Gerstmann Syndrome	1.6%
629	Hearing Loss, Bilateral	1.6%
630	Hearing Loss, High-Frequency	1.6%
631	Hearing Loss, Mixed Conductive-Sensorineural	1.6%
632	Prosopagnosia	1.6%
633	Apraxia, Ideomotor	1.6%
634	Charles Bonnet Syndrome	1.6%
635	Hearing Loss, Unilateral	1.6%
636	Complete Hearing Loss	1.6%
637	Alien Hand Syndrome	1.6%
638	Deaf Mutism	1.6%
639	Subclavian Steal Syndrome	1.6%
640	Pick Disease of the Brain	1.6%
641	Cataplexy	1.6%
642	Aphasia	1.6%
643	Articulation Disorders	1.6%
644	Echolalia	1.6%
645	Stuttering	1.6%
646	Dysphasia	1.6%
647	Kernicterus	1.4%
648	Dysarthria	1.4%
649	Corneal Scar	1.4%
650	Menkes Kinky Hair Syndrome	1.3%
651	Retrograde amnesia	1.3%
652	Amnesia, Anterograde	1.3%
653	Carotid Artery Thrombosis	1.3%
654	Waterhouse-Friderichsen Syndrome	1.3%
655	Mutism	1.3%
656	Selective Mutism	1.3%
657	Acromegaly	1.3%
658	Cerebral Amyloid Angiopathy	1.3%
659	Rubinstein-Taybi Syndrome	1.3%
660	Sinus Thrombosis, Intracranial	1.3%
661	Fragile X Syndrome	1.1%
662	Alexia, Pure	1.1%
663	Cavernous Sinus Thrombosis	1.1%
664	Sagittal Sinus Thrombosis	1.1%
665	Corneal Perforation	1.1%
666	Galactosemias	1%
667	Urea Cycle Disorders, Inborn	1%
668	Tyrosinemias	1%
669	Fabry Disease	1%
670	Nelson Syndrome	0.9%
671	Prolactinoma	0.9%
672	Growth Hormone-Secreting Pituitary Adenoma	0.9%
673	Homocystinuria	0.9%
674	Leigh Disease	0.9%
675	Mucopolysaccharidosis II	0.8%
676	Carbamoyl-Phosphate Synthase I Deficiency Disease	0.7%
677	Zellweger Syndrome	0.7%
678	Glycogen storage disease type II	0.6%
679	Gaucher Disease	0.5%
680	Tay-Sachs Disease	0.4%
681	Niemann-Pick Disease, Type C	0.4%

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