MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Dermatofibrosarcoma

(UMLS:C0206647)

Definition:: A sarcoma of the deep layers of the skin. The tumors are locally aggressive tends to recur but rarely metastatic. It can be classified into variants depending on the cell type tumors are derived from or by its characteristics: Pigmented variant from MELANIN-containing DERMAL DENDRITIC CELLS; Myxoid variant, myxoid STROMAL CELLS; Giant cell variant characterized by GIANT CELLS in the tumors; and Fibrosarcomatous variant chracterized by tumor areas histologically indistinguishable from FIBROSARCOMA.
UMLS ID:: C0206647
MeSH ID:: D018223

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.450.565.590.350.320|C04.557.450.795.350.320

Synonym(s)

Dermatofibrosarcoma

DERMATOFIBROSARCOMA

Dermatofibrosarcoma NOS

Dermatofibrosarcoma, NOS

dermatofibrosarcoma

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Fingolimod Hydrochloride	FAERS: 1		US FAERS
2	Imatinib Mesylate	FAERS: 1		US FAERS
3	Clofibrate		508572	CTD
4	Clomiphene			OFFSIDES
5	Niacinamide			OFFSIDES
6	Ribavirin			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Chondrosarcoma	48.3%
2	synovial sarcoma	48.3%
3	Clear Cell Sarcoma of Soft Tissue	48.3%
4	Malignant Fibrous Histiocytoma	41.3%
5	leiomyosarcoma	40.3%
6	liposarcoma	40.3%
7	Alveolar Soft Part Sarcoma	40.3%
8	Osteosarcoma	39.4%
9	Carcinosarcoma	36.6%
10	Hemangiosarcoma	36.6%
11	lymphangiosarcoma	36.6%
12	Neurofibrosarcoma	35.4%
13	Phyllodes Tumor	33.2%
14	Desmoplastic Small Round Cell Tumor	33.2%
15	fibroma	31.9%
16	Fibromatosis	31.9%
17	Sarcoma, Myeloid	31.5%
18	Myxoma	31%
19	Neoplasms, Bone Tissue	31%
20	Chondroma	31%
21	Enchondroma	31%
22	Angiomyolipoma	30.7%
23	Giant Cell Tumor of Bone	28.9%
24	leukemia	28.8%
25	Neoplasms, Germ Cell and Embryonal	28.8%
26	Neoplasms, Glandular and Epithelial	28.8%
27	Germ Cell Cancer	28.8%
28	Sarcoma, Experimental	26.1%
29	Rhabdomyosarcoma	25.7%
30	Carcinoma 256, Walker	24.2%
31	Neuroectodermal Tumors	23.1%
32	Adenofibroma	23%
33	Fibroadenoma	23%
34	Fibromatosis, Aggressive	21.8%
35	Fibromatosis, Abdominal	21.8%
36	Histiocytic Disorders, Malignant	21.6%
37	Lipoma	20.4%
38	Myoma	20.4%
39	Angiolipoma	20.4%
40	Myelolipoma	20.4%
41	Smooth Muscle Tumor	20.4%
42	Sarcoma 180	20%
43	Neoplasms, Neuroepithelial	19.8%
44	Gliomatosis cerebri	19.8%
45	Osteoblastoma	19.3%
46	Osteoma	19.3%
47	Chondromatosis	19.3%
48	Mastocytosis	19.2%
49	Hamartoma	19.2%
50	Neoplasms, Hormone-Dependent	19.2%
51	Neoplasms, Multiple Primary	19.2%
52	Paraneoplastic Syndromes	19.2%
53	Precancerous Conditions	19.2%
54	Neoplasms, Second Primary	19.2%
55	Gastrointestinal Stromal Tumors	19%
56	Alveolar rhabdomyosarcoma	18.5%
57	Endometrial Stromal Sarcoma	18.3%
58	Lymphoma	17.4%
59	Sarcoma	16.9%
60	Meningioma	16.3%
61	melanoma	15.8%
62	Composite Lymphoma	15.4%
63	Adenoma	15.3%
64	Ameloblastoma	15.3%
65	Angiokeratoma	15.3%
66	Carcinoma	15.3%
67	Chordoma	15.3%
68	Hemangioma	15.3%
69	hemangiopericytoma	15.3%
70	Lymphangioma	15.3%
71	Mesenchymoma	15.3%
72	Nevus	15.3%
73	Teratoma	15.3%
74	Hepatoblastoma	15.3%
75	Mixed Tumor, Mullerian	15.3%
76	Germinoma	15.3%
77	Teratocarcinoma	15.3%
78	Angiofibroma	15.3%
79	Epithelioma	15.3%
80	Trophoblastic Neoplasms	15.2%
81	Leukemia, Experimental	15.1%
82	Lymphangioleiomyomatosis	14.7%
83	Mastocytoma	14.6%
84	Cyst	14.5%
85	Neoplastic Processes	14.5%
86	Neoplastic Syndromes, Hereditary	14.5%
87	Pregnancy Complications, Neoplastic	14.5%
88	Mastocytosis, Systemic	14.5%
89	Leukemia, Plasma Cell	14.5%
90	Neoplasms, Experimental	14.3%
91	Carcinoma, Ehrlich Tumor	13.9%
92	Dermoid Cyst	13.9%
93	Carcinoma, Lewis Lung	13.9%
94	Dupuytren Contracture	13.6%
95	Basal cell carcinoma	13.2%
96	Carcinoma, Papillary	13.2%
97	Squamous cell carcinoma	13.2%
98	Craniopharyngioma	13.2%
99	Cystadenoma	13.2%
100	Mesothelioma	13.2%
101	Neuroectodermal Tumor, Melanotic	13.2%
102	Neuroendocrine Tumors	13.2%
103	Carcinoma, Basal Cell	13.2%
104	Rhabdomyoma	12.9%
105	Leukemia, Radiation-Induced	12.8%
106	Fibrosarcoma	12.5%
107	Adenoma, Acidophil	11.9%
108	Ganglioneuroma	11.9%
109	Glioma	11.9%
110	Malignant Glioma	11.9%
111	Plasmacytoma	11.6%
112	Malignant histiocytosis	11.5%
113	Histiocytic sarcoma	11.5%
114	Neoplasms, Radiation-Induced	11.5%
115	Melanoma, Experimental	11.3%
116	Neoplasms, Fibrous Tissue	11.1%
117	Thymoma	11%
118	Multiple Endocrine Neoplasia	10.7%
119	Cystadenocarcinoma	10.7%
120	Mucoepidermoid Carcinoma	10.7%
121	Leukemia L1210	10.5%
122	Leukemia P388	10.5%
123	Acanthoma	10.5%
124	Medulloblastoma	10.1%
125	Carcinoid Tumor	10%
126	Neurilemmoma	10%
127	Hutchinson's Melanotic Freckle	10%
128	Melanoma, Amelanotic	10%
129	Choriocarcinoma	9.8%
130	Carcinoma, Lobular	9.8%
131	Abdominal Neoplasms	9.6%
132	Erythroplasia	9.6%
133	Follicular cyst	9.6%
134	Head and Neck Neoplasms	9.6%
135	Mucocele	9.6%
136	Pilonidal Cyst	9.6%
137	Soft Tissue Neoplasms	9.6%
138	Thoracic Neoplasms	9.6%
139	Thyroglossal Cyst	9.6%
140	Synovial Cyst	9.6%
141	Aberrant Crypt Foci	9.6%
142	Hodgkin Disease	9.2%
143	Lymphoma, Non-Hodgkin	9.2%
144	Paraneoplastic Encephalomyelitis	9%
145	Mammary Neoplasms, Experimental	8.9%
146	Adenocarcinoma	8.8%
147	Carcinoma in Situ	8.8%
148	Carcinoma, Transitional Cell	8.8%
149	Dysgerminoma	8.8%
150	Hemangioendothelioma	8.8%
151	Neuroma	8.8%
152	Papilloma	8.8%
153	Pseudomyxoma Peritonei	8.8%
154	Seminoma	8.8%
155	Papillomatosis	8.8%
156	Adenomatosis, Pulmonary	8.8%
157	Adenomatous Polyps	8.8%
158	Carcinoma, Large Cell	8.8%
159	Carcinoma, Small Cell	8.8%
160	Bowen's Disease	8.3%
161	Paraganglioma	8.3%
162	Dermatofibrosarcoma	8.3%
163	Dermatofibrosarcoma Protuberans	8.3%
164	Urticaria Pigmentosa	8.2%
165	Astrocytoma	8.1%
166	Ependymoma	8.1%
167	oligodendroglioma	8.1%
168	Ganglioglioma	8.1%
169	gliosarcoma	8.1%
170	Anaplastic astrocytoma	8.1%
171	Anaplastic Oligodendroglioma	8.1%
172	Nephroblastoma	8%
173	Tuberous Sclerosis	8%
174	Retinoblastoma	7.8%
175	Primary amyloidosis	7.7%
176	Digestive System Neoplasms	7.6%
177	Endocrine Gland Neoplasms	7.6%
178	Eye Neoplasms	7.6%
179	Nervous System Neoplasms	7.6%
180	Lymphomatoid Granulomatosis	7.5%
181	Bone neoplasms	7.3%
182	Leukoplakia	7.3%
183	Lymphocele	7.3%
184	Pancreatic Cyst	7.3%
185	Skin Neoplasms	7.3%
186	Hematologic Neoplasms	7.3%
187	Barrett Esophagus	7.2%
188	Breast Cyst	7.2%
189	Actinic keratosis	7.2%
190	Mediastinal Cyst	7.2%
191	Neoplasm Invasiveness	7.2%
192	Neoplasm Metastasis	7.2%
193	Neoplasm Recurrence, Local	7.2%
194	Parovarian Cyst	7.2%
195	Pericardial Cyst	7.2%
196	Splenic Neoplasms	7.2%
197	Thymic Cyst	7.2%
198	Carcinogenesis	7.2%
199	Myxoid cyst	7.2%
200	Metastasis	7.2%
201	Malignant Carcinoid Syndrome	7.1%
202	Leukemia, Myelomonocytic, Chronic	6.6%
203	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	6.6%
204	Mesoblastic Nephroma	6.4%
205	Basal Cell Nevus Syndrome	6.2%
206	Glioblastoma	6.1%
207	Neuroblastoma	6.1%
208	Glioblastoma Multiforme	6.1%
209	Hepatocellular Adenoma	5.9%
210	Pheochromocytoma	5.9%
211	Waldenstrom Macroglobulinemia	5.8%
212	Multiple Myeloma	5.8%
213	Corpus Luteum Cyst	5.7%
214	Ovarian Cysts	5.7%
215	Multiple Endocrine Neoplasia Type 1	5.7%
216	Adenoid Cystic Carcinoma	5.5%
217	Adenocarcinoma, Clear Cell	5.5%
218	Cholangiocarcinoma	5.5%
219	Cervical Intraepithelial Neoplasia	5.5%
220	Hemangioblastoma	5.5%
221	Lymphoma, Extranodal NK-T-Cell	5.5%
222	Sturge-Weber Syndrome	5.4%
223	Liver Neoplasms, Experimental	5.4%
224	Hemangioma, Cavernous	5.3%
225	Parathyroid Neoplasms	5.3%
226	Peritoneal Neoplasms	5.3%
227	Thyroid Neoplasm	5.3%
228	Thyroid carcinoma	5.3%
229	Leukemia, T-Cell	5.3%
230	Leukemia, B-Cell	5.3%
231	neurofibroma	5.3%
232	Lymphoma, Follicular	5.2%
233	T-Cell Lymphoma	5.2%
234	Mantle cell lymphoma	5.2%
235	Carcinoma, Pancreatic Ductal	5.2%
236	Ganglioneuroblastoma	5.2%
237	Retroperitoneal Neoplasms	5.1%
238	Hydatidiform Mole	5.1%
239	Prolactinoma	5.1%
240	Growth Hormone-Secreting Pituitary Adenoma	5.1%
241	Choledochal Cyst	4.9%
242	Carcinoid Heart Disease	4.8%
243	Peutz-Jeghers Syndrome	4.8%
244	Acoustic Neuroma	4.6%
245	Pancreatic Neoplasm	4.6%
246	Adenomatous Polyposis Coli	4.5%
247	granulosa cell tumor	4.4%
248	Carcinoma, Ovarian Epithelial	4.4%
249	Optic Nerve Glioma	4.2%
250	Tracheal Neoplasms	4.2%
251	Leukemia, Myeloid, Chronic-Phase	4.2%
252	Leukoplakia, Oral	4.1%
253	Paraneoplastic Cerebellar Degeneration	4%
254	Klatskin Tumor	3.9%
255	Mouth Neoplasms	3.9%
256	Central Nervous System Neoplasms	3.9%
257	Vascular Neoplasms	3.9%
258	Thymus Neoplasms	3.9%
259	Vipoma	3.9%
260	Genital Neoplasms, Female	3.9%
261	Pancreatic Pseudocyst	3.9%
262	Lymphatic Metastasis	3.8%
263	Neoplasms, Unknown Primary	3.8%
264	Leukemic Infiltration	3.8%
265	Breast Neoplasms, Male	3.8%
266	Neoplasm Micrometastasis	3.8%
267	Triple Negative Breast Neoplasms	3.8%
268	Esophageal Neoplasms	3.5%
269	insulinoma	3.5%
270	Limbic Encephalitis	3.5%
271	Nasopharyngeal carcinoma	3.4%
272	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	3.3%
273	Leukemia, Large Granular Lymphocytic	3.3%
274	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	3.3%
275	Lymphoma, T-Cell, Cutaneous	3.3%
276	Lymphoma, AIDS-Related	3.3%
277	Enteropathy-Associated T-Cell Lymphoma	3.3%
278	Primary Effusion Lymphoma	3.3%
279	Denys-Drash Syndrome	3.2%
280	Adrenocortical carcinoma	3.2%
281	Adrenal Gland Neoplasms	3.2%
282	Gastrointestinal Neoplasms	3.2%
283	Genital Neoplasms, Male	3.2%
284	Liver neoplasms	3.2%
285	Uveal Neoplasms	3.2%
286	Urologic Neoplasms	3.1%
287	Sebaceous Gland Neoplasms	3.1%
288	Spinal Neoplasms	3.1%
289	Bone Marrow Neoplasms	3.1%
290	Lambert-Eaton Myasthenic Syndrome	3.1%
291	Testicular Neoplasms	3.1%
292	Polycystic Ovary Syndrome	3%
293	Thyroid Nodule	3%
294	Leydig Cell Tumor	2.9%
295	Xeroderma Pigmentosum	2.9%
296	Gastrinoma	2.9%
297	Glucagonoma	2.9%
298	Renal Cell Carcinoma	2.8%
299	Papillary Renal Cell Carcinoma	2.8%
300	Opsoclonus-Myoclonus Syndrome	2.7%
301	Carcinoma, Endometrioid	2.6%
302	Myelitis, Transverse	2.4%
303	Burkitt Lymphoma	2.4%
304	Mycosis Fungoides	2.4%
305	Lymphomatoid Papulosis	2.4%
306	Plasmablastic lymphoma	2.4%
307	ovarian neoplasm	2.2%
308	Meningeal Neoplasms	2.2%
309	Nose Neoplasms	2.1%
310	Pituitary Adenoma	1.9%
311	Pituitary Neoplasms	1.9%
312	Ear Neoplasms	1.8%
313	Eyelid Neoplasms	1.8%
314	Lung Neoplasms	1.8%
315	Pleural Neoplasms	1.8%
316	Palatal Neoplasms	1.8%
317	Cell Transformation, Viral	1.8%
318	Brain Neoplasms	1.8%
319	Salivary Gland Neoplasms	1.8%
320	Spinal Cord Neoplasms	1.8%
321	Tongue Neoplasms	1.8%
322	Uterine Neoplasms	1.8%
323	Vaginal Neoplasms	1.8%
324	Vulvar Neoplasms	1.8%
325	Uterine Cancer	1.8%
326	Fallopian Tube Neoplasms	1.8%
327	Zollinger-Ellison syndrome	1.7%
328	Sezary Syndrome	1.7%
329	Pharyngeal Neoplasms	1.5%
330	Central Nervous System Cysts	1.5%
331	Bile Duct Neoplasms	1.5%
332	gallbladder neoplasm	1.5%
333	Intestinal Neoplasms	1.5%
334	Penile Neoplasms	1.5%
335	Prostatic Neoplasms	1.5%
336	Stomach Neoplasms	1.5%
337	Polycythemia Vera	1.5%
338	Meningeal Carcinomatosis	1.4%
339	Laryngeal neoplasm	1.3%
340	Bladder Neoplasm	1.3%
341	Kidney Neoplasm	1.3%
342	Ureteral Neoplasms	1.3%
343	Urethral Neoplasms	1.3%
344	Bronchial Neoplasms	1.1%
345	Multiple Pulmonary Nodules	1.1%
346	Supratentorial Neoplasms	1.1%
347	Endometrial Neoplasms	1.1%
348	Hypopharyngeal Neoplasms	0.9%
349	Pleural Effusion, Malignant	0.9%
350	Hypopharyngeal Cancer	0.9%
351	Parotid Neoplasms	0.9%
352	Prostatic Neoplasms, Castration-Resistant	0.9%
353	Nelson Syndrome	0.9%
354	Cecal Neoplasms	0.8%
355	Duodenal Neoplasms	0.8%
356	Brain Stem Neoplasms	0.8%
357	Nasopharyngeal Neoplasms	0.7%
358	Colorectal Neoplasms	0.7%
359	Tonsillar Neoplasms	0.7%
360	Cerebellar Neoplasms	0.7%
361	Paranasal Sinus Neoplasms	0.6%
362	Choroid Plexus Papilloma	0.6%
363	Radicular Cyst	0.6%
364	Appendiceal Neoplasms	0.6%
365	Colonic Neoplasms	0.6%
366	Rectal Neoplasms	0.6%
367	Maxillary Sinus Neoplasms	0.4%
368	Anus Neoplasms	0.4%
369	Sigmoid Neoplasms	0.4%

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