MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Malaria, Cerebral

(UMLS:C0024534)

Definition:: A condition characterized by somnolence or coma in the presence of an acute infection with PLASMODIUM FALCIPARUM (and rarely other Plasmodium species). Initial clinical manifestations include HEADACHES; SEIZURES; and alterations of mentation followed by a rapid progression to COMA. Pathologic features include cerebral capillaries filled with parasitized erythrocytes and multiple small foci of cortical and subcortical necrosis. (From Adams et al., Principles of Neurology, 6th ed, p136)
UMLS ID:: C0024534
MeSH ID:: D016779

Classification 1:

Name:

Parasitic Diseases
MeSH Tree Number(s):: C03.105.300.500|C03.752.530.620

Classification 2:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.228.205.300.500

Synonym(s)

Malaria, Cerebral

CEREBRAL MALARIA

Cerebral Malaria

Cerebral malaria

Malarial encephalitis

cerebral malaria

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Mefloquine		8644976	CTD
2	Quinine		8644976	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Toxoplasmosis, Cerebral	29.3%
2	Malaria, Falciparum	26.3%
3	Malaria, Vivax	26.3%
4	Toxoplasmosis, Congenital	23.6%
5	Encephalomyelitis	20.7%
6	Protozoan Infections, Animal	20.5%
7	Giardiasis	20.2%
8	Amebiasis	20.1%
9	Coccidiosis	20.1%
10	Acanthamoeba Infection	20.1%
11	Trichomonas Infections	20.1%
12	Ciliophora Infections	20.1%
13	Balamuthia Infection	20.1%
14	Blackwater Fever	19.6%
15	Neurocysticercosis	19.5%
16	Cryptosporidiosis	19.2%
17	Babesiosis	18.9%
18	Meningoencephalitis	18.7%
19	Helminthiasis	17.3%
20	Epidural Abscess	16.6%
21	Myelitis	16.5%
22	Leishmaniasis	15.5%
23	Prion Diseases	14.7%
24	Parasitic Diseases, Animal	14.3%
25	Liver Diseases, Parasitic	13.9%
26	Intestinal Diseases, Parasitic	13.7%
27	Pregnancy Complications, Parasitic	13.7%
28	Helminthiasis, Animal	13.7%
29	Parasitemia	13.6%
30	Acanthamoeba Keratitis	13.4%
31	Entamoebiasis	13.2%
32	Toxoplasmosis	13.2%
33	Trypanosomiasis	13.2%
34	Isosporiasis	13.2%
35	Opportunistic Infections	11.9%
36	Brain Abscess	11.9%
37	Subdural Effusion	11.8%
38	Central Nervous System Fungal Infections	11.7%
39	Liver Abscess, Amebic	11.6%
40	Brain Diseases	11.3%
41	Meningitis	11.3%
42	Movement Disorders	11.3%
43	Pachymeningitis	11.3%
44	Spinal Cord Diseases	11.3%
45	Fascioliasis	11.1%
46	Larva Migrans	11.1%
47	Leishmaniasis, Cutaneous	10.9%
48	Ocular Motility Disorders	10.5%
49	Cyclophoria	10.5%
50	Trichomonas Vaginitis	10.5%
51	Cestode Infections	10%
52	Nematode infections	10%
53	Trematode Infections	10%
54	Echinococcosis, Hepatic	10%
55	Meningitis, Bacterial	9.9%
56	Meningitis, Fungal	9.9%
57	Toxocariasis	9.9%
58	Central Nervous System Bacterial Infections	9.9%
59	Leishmaniasis, Visceral	9.8%
60	African Trypanosomiasis	9.8%
61	Chagas Disease	9.8%
62	Cerebral Ventriculitis	9.8%
63	Dirofilariasis	9.6%
64	Pneumocephalus	9.2%
65	Poliomyelitis	9.2%
66	Onchocerciasis	9.1%
67	Multiple System Atrophy	9%
68	Strongyle Infections, Equine	8.7%
69	Protozoan Infections	8.7%
70	Creutzfeldt-Jakob disease	8.2%
71	Stiff-Person Syndrome	8%
72	Parkinsonian Disorders	7.9%
73	Tuberculosis, Meningeal	7.4%
74	Cranial nerve diseases	7.4%
75	Demyelinating Diseases	7.4%
76	Demyelination	7.4%
77	Neuromuscular Diseases	7.4%
78	Chronobiology Disorders	7.4%
79	Scrapie	7.2%
80	Limbic Encephalitis	7.2%
81	Lupus Vasculitis, Central Nervous System	7.1%
82	Leukoencephalopathy, Progressive Multifocal	7%
83	Spinal Cord Injuries	6.9%
84	Subacute Combined Degeneration	6.9%
85	Spinal Muscular Atrophy	6.9%
86	Progressive Muscular Atrophy	6.9%
87	Tuberculosis, Central Nervous System	6.8%
88	Lewy Body Disease	6.8%
89	Superinfection	6.8%
90	Myelitis, Transverse	6.7%
91	Asterixis	6.7%
92	Ballismus	6.7%
93	Parkinson Disease	6.6%
94	Diphyllobothriasis	6.6%
95	Echinococcosis	6.6%
96	Hymenolepiasis	6.6%
97	Mite Infestations	6.6%
98	Myiasis	6.6%
99	Opisthorchiasis	6.6%
100	Schistosomiasis	6.6%
101	Tick Infestations	6.6%
102	Secernentea Infections	6.6%
103	Chagas Cardiomyopathy	6.5%
104	Dandy-Walker Syndrome	6.4%
105	Amyotrophic Lateral Sclerosis	6.2%
106	Akinetic Mutism	6.2%
107	Anoxic Encephalopathy	6.2%
108	Arachnoiditis	6.2%
109	Basal Ganglia Diseases	6.2%
110	Brain Damage, Chronic	6.2%
111	Cerebellar Diseases	6.2%
112	Encephalitis	6.2%
113	Encephalomalacia	6.2%
114	Epilepsy	6.2%
115	Hydrocephalus	6.2%
116	Congenital Hydrocephalus	6.2%
117	Hypothalamic Diseases	6.2%
118	Aseptic Meningitis	6.2%
119	Syringomyelia	6.2%
120	Thalamic Diseases	6.2%
121	Intracranial Hypertension	6.2%
122	Aura	6.2%
123	Leukoencephalopathy	6.2%
124	Essential Tremor	6.2%
125	Neuroaxonal Dystrophies	6.2%
126	Familial Tremor	6.2%
127	Headache Disorders	6.2%
128	Intracranial Hypotension	6.2%
129	Brain Edema	6.2%
130	Brain Hypoxia	6.2%
131	Aqueductal Stenosis	6.2%
132	Pneumorrhachis	6.2%
133	Writer's Cramp	6.2%
134	Motor Neuron Disease	6.1%
135	Trauma, Nervous System	6.1%
136	Marchiafava-Bignami Disease	6%
137	Chronic Fatigue Syndrome	6%
138	Nervous System Neoplasms	5.9%
139	Neurologic Manifestations	5.9%
140	Neurotoxicity Syndromes	5.9%
141	Meige Syndrome	5.9%
142	Neuroaspergillosis	5.8%
143	Progressive supranuclear palsy	5.7%
144	Brain Injuries	5.5%
145	Brain Neoplasms	5.5%
146	Spinal Cord Neoplasms	5.5%
147	Dystonia Musculorum Deformans	5.4%
148	Meningitis, Cryptococcal	5.3%
149	Striatonigral Degeneration	5.3%
150	Subacute Sclerosing Panencephalitis	5.3%
151	Meningitis, Listeria	5.3%
152	Meningitis, Haemophilus	5.3%
153	Meningitis, Pneumococcal	5.3%
154	Restless Legs Syndrome	5.3%
155	Lice Infestations	5.2%
156	Pseudorabies	5.1%
157	Dementia, Vascular	5.1%
158	Polyradiculoneuropathy	5%
159	Polyradiculoneuritis	5%
160	Malaria	5%
161	AIDS-Related Opportunistic Infections	5%
162	Akathisia, Drug-Induced	5%
163	Brain Diseases, Metabolic	5%
164	Cerebrovascular Disorders	5%
165	Cerebrovascular Insufficiency	5%
166	Dementia	5%
167	Conus Medullaris Syndrome	5%
168	Spinal Cord Vascular Diseases	5%
169	Sleep Wake Disorders	5%
170	Neuroleptic Malignant Syndrome	5%
171	Myelinolysis, Central Pontine	5%
172	Basal Ganglia Cerebrovascular Disease	4.9%
173	Cysticercosis	4.9%
174	Hypodermyiasis	4.9%
175	Schistosomiasis japonica	4.9%
176	Schistosomiasis mansoni	4.9%
177	Sparganosis	4.9%
178	Ascaridida Infections	4.9%
179	Oxyurida Infections	4.9%
180	Epilepsy, Post-Traumatic	4.9%
181	Neurosyphilis	4.9%
182	Posterior Leukoencephalopathy Syndrome	4.9%
183	Posterior reversible encephalopathy syndrome	4.9%
184	Huntington Disease	4.8%
185	Ophthalmoplegic Migraine	4.7%
186	Shy-Drager Syndrome	4.7%
187	Autonomic Dysreflexia	4.7%
188	Complex Regional Pain Syndromes	4.7%
189	Opsoclonus-Myoclonus Syndrome	4.6%
190	MPTP Poisoning	4.6%
191	Brain Death	4.5%
192	Malaria, Cerebral	4.4%
193	Dyskinesia, Drug-Induced	4.3%
194	Lyme Neuroborreliosis	4.3%
195	Amblyopia	4.2%
196	Leukomalacia, Periventricular	4.2%
197	Hepatolenticular Degeneration	4.1%
198	Vascular Headaches	4.1%
199	Ascariasis	4.1%
200	Filariasis	4.1%
201	Gnathostomiasis	4.1%
202	Hookworm Infections	4.1%
203	Oxyuriasis	4.1%
204	Strongyloidiasis	4.1%
205	Trichinellosis	4.1%
206	Trichostrongyloidiasis	4.1%
207	Hypoxia-Ischemia, Brain	4.1%
208	Peripheral Nerve Injuries	3.9%
209	Cerebellar Neoplasms	3.9%
210	Leukoencephalitis, Acute Hemorrhagic	3.9%
211	Myasthenia Gravis	3.9%
212	Myoclonic Epilepsy	3.9%
213	Epilepsy, Temporal Lobe	3.9%
214	Epilepsy, Rolandic	3.9%
215	Benign Rolandic Epilepsy	3.9%
216	Central Cord Syndrome	3.9%
217	Presenile dementia	3.8%
218	Senile dementia	3.8%
219	Chorea	3.8%
220	Dysautonomia	3.8%
221	Vagus Nerve Disorder	3.8%
222	Glossopharyngeal Neuralgia	3.8%
223	Abducens Nerve Diseases	3.8%
224	Heavy Metal Poisoning, Nervous System	3.8%
225	Neuromuscular Junction Diseases	3.8%
226	Tauopathies	3.8%
227	Trochlear Nerve Diseases	3.8%
228	Peripheral Nervous System Diseases	3.8%
229	Vasculitis, Central Nervous System	3.7%
230	Encephalomyelitis, Acute Disseminated	3.7%
231	Cerebral Palsy	3.7%
232	Epilepsies, Partial	3.7%
233	Epilepsy, Generalized	3.7%
234	Pseudotumor Cerebri	3.7%
235	Hypertensive Encephalopathy	3.7%
236	Simple Partial Seizures	3.7%
237	Epilepsy, Reflex	3.7%
238	Headache Disorders, Primary	3.7%
239	Headache Disorders, Secondary	3.7%
240	Medication overuse headache	3.7%
241	Friedreich Ataxia	3.7%
242	West Nile Fever	3.7%
243	Loiasis	3.7%
244	Enterobiasis	3.7%
245	Miller Fisher Syndrome	3.6%
246	Lambert-Eaton Myasthenic Syndrome	3.5%
247	Guillain-Barre Syndrome	3.5%
248	Amnesia, Transient Global	3.5%
249	Sleep Disorders, Circadian Rhythm	3.4%
250	Botulism	3.3%
251	Central Nervous System Cysts	3.3%
252	Progressive bulbar palsy	3.3%
253	Bulbar palsy	3.3%
254	Paraneoplastic Cerebellar Degeneration	3.3%
255	Brain Injuries, Diffuse	3.3%
256	Traumatic Brain Injury	3.3%
257	Cerebellar Ataxia	3.2%
258	Supratentorial Neoplasms	3.2%
259	Torticollis	3.2%
260	Brain Hemorrhage, Traumatic	3.1%
261	Myopathy	3.1%
262	Optic Neuropathy	3.1%
263	Carotid Artery Injuries	3.1%
264	Pituitary Diseases	3.1%
265	Facial Nerve Diseases	3.1%
266	Craniocerebral Trauma	3.1%
267	Parasomnia	3.1%
268	Dyssomnias	3.1%
269	Olfactory Nerve Injuries	3%
270	Canavan Disease	3%
271	Alexander Disease	3%
272	Vestibulocochlear Nerve Diseases	3%
273	Decerebrate State	3%
274	Hemiparesis	3%
275	Hydranencephaly	3%
276	Meningism	3%
277	Neural Tube Defects	3%
278	Paresis	3%
279	Seizures	3%
280	Sensation Disorders	3%
281	Tethered Cord Syndrome	3%
282	Central Nervous System Neoplasms	3%
283	Complex partial seizures	3%
284	Iniencephaly	3%
285	Craniorachischisis	3%
286	Exencephaly	3%
287	Monoparesis	3%
288	Septo-Optic Dysplasia	3%
289	Cortical Dysplasia	3%
290	Neurogenic Inflammation	3%
291	Gait Disorders, Neurologic	3%
292	Neuromuscular Manifestations	3%
293	Malformations of Cortical Development	3%
294	Causalgia	3%
295	Sweating, Gustatory	3%
296	Auriculotemporal Syndrome	3%
297	Persistent Vegetative State	3%
298	Carotid Artery Diseases	3%
299	Brain Ischemia	3%
300	Cerebrovascular accident	3%
301	Kluver-Bucy Syndrome	3%
302	Vasospasm, Intracranial	3%
303	Spinal Cord Ischemia	3%
304	Intracranial Arterial Diseases	3%
305	Basal Ganglia Hemorrhage	2.9%
306	Lafora Disease	2.9%
307	Unverricht-Lundborg Syndrome	2.9%
308	Juvenile Myoclonic Epilepsy	2.9%
309	Myoclonic Epilepsies, Progressive	2.9%
310	Horner Syndrome	2.8%
311	Neuromyelitis Optica	2.8%
312	Pituitary Apoplexy	2.8%
313	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	2.8%
314	Brain Infarction	2.8%
315	Multiple Sclerosis	2.7%
316	Pituitary Adenoma	2.7%
317	Pituitary Neoplasms	2.7%
318	Facial Nerve Injuries	2.7%
319	Reflex Sympathetic Dystrophy	2.6%
320	Nocturnal Myoclonus Syndrome	2.6%
321	Pupil Disorders	2.6%
322	Neurobehavioral Manifestations	2.6%
323	Paraneoplastic Encephalomyelitis	2.5%
324	Ataxia Telangiectasia	2.5%
325	Uveomeningoencephalitic Syndrome	2.5%
326	Sturge-Weber Syndrome	2.5%
327	Vertigo	2.5%
328	Alcohol-Induced Disorders, Nervous System	2.5%
329	Jet Lag Syndrome	2.5%
330	Reye Syndrome	2.5%
331	Mitochondrial Encephalomyopathies	2.5%
332	Intracranial Embolism and Thrombosis	2.5%
333	Hepatic Encephalopathy	2.5%
334	Post-Traumatic Headache	2.4%
335	Tension Headache	2.4%
336	Epilepsy, Complex Partial	2.4%
337	Migraine Disorders	2.4%
338	Abdominal Migraine	2.4%
339	Status Migrainosus	2.4%
340	Cervicogenic Headache	2.4%
341	Tardive Dyskinesia	2.4%
342	Tuberous Sclerosis	2.4%
343	Ophthalmoplegia	2.4%
344	External Ophthalmoplegia	2.4%
345	Myasthenia Gravis, Autoimmune, Experimental	2.4%
346	Putaminal Hemorrhage	2.3%
347	Vertebral Artery Dissection	2.2%
348	Waterhouse-Friderichsen Syndrome	2.2%
349	Voice Disorders	2.2%
350	Voice Disturbance	2.2%
351	Acrodynia	2.2%
352	Auditory Perceptual Disorders	2.2%
353	Diffuse Axonal Injury	2.2%
354	Smith-Magenis syndrome	2.1%
355	Brain Stem Neoplasms	2.1%
356	Dural Arteriovenous Fistula	2.1%
357	Infarction, Middle Cerebral Artery	2.1%
358	Infarction, Anterior Cerebral Artery	2.1%
359	Infarction, Posterior Cerebral Artery	2.1%
360	Moyamoya Disease	2.1%
361	Brain Diseases, Metabolic, Inborn	2.1%
362	Vocal Cord Paralysis	2.1%
363	Frontotemporal dementia	2.1%
364	Cerebral Infarction	2.1%
365	Brain Stem Infarctions	2.1%
366	Neuritis	2.1%
367	Polyneuritis	2.1%
368	Radiculitis	2.1%
369	Polyneuropathy	2.1%
370	Mononeuritis	2.1%
371	Mononeuropathies	2.1%
372	Brachial Plexus Neuropathies	2.1%
373	Radiculopathy	2.1%
374	Mononeuropathy Multiplex	2.1%
375	Nerve Root Compression	2.1%
376	Charcot-Marie-Tooth Disease	2%
377	Adrenoleukodystrophy	2%
378	Empty Sella Syndrome	2%
379	Hyperpituitarism	2%
380	Hypopituitarism	2%
381	Hypophysitis	2%
382	Brain Concussion	2%
383	Brachial Plexus Neuritis	2%
384	Neuralgic Amyotrophy	2%
385	Cerebral Arterial Diseases	1.9%
386	Vertebrobasilar Insufficiency	1.9%
387	Anterior Spinal Artery Syndrome	1.9%
388	Basilar Artery Stenosis	1.9%
389	Vertebral Artery Stenosis	1.9%
390	Intracranial Hemorrhage, Hypertensive	1.9%
391	Transient Cerebral Ischemia	1.9%
392	Subarachnoid Hemorrhage, Traumatic	1.9%
393	Carotid Artery, Internal, Dissection	1.9%
394	Alice in Wonderland Syndrome	1.9%
395	Myotonia Congenita	1.9%
396	MELAS Syndrome	1.9%
397	Cerebrospinal Fluid Otorrhea	1.9%
398	Cerebrospinal Fluid Rhinorrhea	1.9%
399	Neuritis, Autoimmune, Experimental	1.9%
400	Gait Ataxia	1.9%
401	Reflex, Abnormal	1.9%
402	Hyporeflexia	1.9%
403	Hyperreflexia	1.9%
404	Brain Contusion	1.9%
405	Refsum Disease	1.8%
406	Wernicke Encephalopathy	1.8%
407	AIDS Dementia Complex	1.8%
408	Cluster Headache	1.8%
409	Migraine with Aura	1.8%
410	Familial Hemiplegic Migraine	1.8%
411	Chronic Paroxysmal Hemicrania	1.8%
412	SUNCT Syndrome	1.8%
413	Paroxysmal Hemicrania	1.8%
414	Alcohol Withdrawal Seizures	1.8%
415	Giant Cell Arteritis	1.8%
416	Temporal Arteritis	1.8%
417	Coma, Post-Head Injury	1.8%
418	Lateral Medullary Syndrome	1.7%
419	Myositis	1.7%
420	Optic Atrophy	1.7%
421	Optic Neuritis	1.7%
422	Papilledema	1.7%
423	Strabismus	1.7%
424	Tolosa-Hunt Syndrome	1.7%
425	Isaacs syndrome	1.7%
426	Arsenic Poisoning	1.7%
427	Myotonic Disorders	1.7%
428	Myasthenic Syndromes, Congenital	1.7%
429	Kernicterus	1.7%
430	Diabetic Neuropathies	1.7%
431	Facial Injuries	1.7%
432	Facial Neuralgia	1.7%
433	Diabetic Amyotrophy	1.7%
434	Diabetic Autonomic Neuropathy	1.7%
435	Sleep Talking	1.7%
436	Manganese Poisoning	1.7%
437	Sleep Disorders, Intrinsic	1.7%
438	Orthostatic intolerance	1.7%
439	Anosmia	1.6%
440	Ataxia	1.6%
441	Athetosis	1.6%
442	Catalepsy	1.6%
443	Dystonia	1.6%
444	Hemiplegia	1.6%
445	Locked-In Syndrome	1.6%
446	Meningeal Neoplasms	1.6%
447	Meningomyelocele	1.6%
448	Muscle Hypertonia	1.6%
449	Muscle hypotonia	1.6%
450	Myoclonus	1.6%
451	Myotonia	1.6%
452	Myotonic Dystrophy	1.6%
453	Neuralgia	1.6%
454	Paraplegia	1.6%
455	Pseudobulbar Palsy	1.6%
456	Quadriplegia	1.6%
457	Spasm	1.6%
458	Spastic Paraplegia	1.6%
459	Status Epilepticus	1.6%
460	Taste Disorders	1.6%
461	Tremor	1.6%
462	Spina Bifida	1.6%
463	Monoplegia	1.6%
464	Hypokinesia	1.6%
465	Paraparesis	1.6%
466	Bradykinesia	1.6%
467	Waxy flexibility	1.6%
468	Action Tremor	1.6%
469	Resting Tremor	1.6%
470	Dysosmia	1.6%
471	Quadriparesis	1.6%
472	Mercury Poisoning, Nervous System	1.6%
473	Olfaction Disorders	1.6%
474	Myokymia	1.6%
475	Lead Poisoning, Nervous System	1.6%
476	Vestibular Neuronitis	1.6%
477	Somatosensory Disorders	1.6%
478	Neuropathic pain	1.6%
479	Hyperkinesia	1.6%
480	Intention tremor	1.6%
481	Akathisia	1.6%
482	Restlessness	1.6%
483	Psychomotor Agitation	1.6%
484	Carotid Stenosis	1.6%
485	Intracranial Aneurysm	1.6%
486	Tarsal Tunnel Syndrome	1.6%
487	Cauda Equina Syndrome	1.6%
488	Intracranial Arteriosclerosis	1.6%
489	Cerebral Atherosclerosis	1.6%
490	Subarachnoid Hemorrhage	1.6%
491	Multiple Sclerosis, Chronic Progressive	1.6%
492	Multiple Sclerosis, Relapsing-Remitting	1.6%
493	Cerebral Arteriosclerosis	1.6%
494	Cerebral Hemorrhage	1.6%
495	Cerebral Thrombosis	1.6%
496	Intracranial Embolism	1.6%
497	Intracranial Thrombosis	1.6%
498	Choroid Plexus Papilloma	1.6%
499	Hyperprolactinemia	1.5%
500	Subclavian Steal Syndrome	1.5%
501	Pick Disease of the Brain	1.5%
502	Hand-Arm Vibration Syndrome	1.4%
503	Gait Apraxia	1.4%
504	Vision Disorders	1.4%
505	Metamorphopsia	1.4%
506	Visual Impairment	1.4%
507	Fibromyalgia	1.4%
508	Optic Neuropathy, Ischemic	1.4%
509	Anterior Ischemic Optic Neuropathy	1.4%
510	Medial Tibial Stress Syndrome	1.4%
511	Facial Hemiatrophy	1.4%
512	Melkersson-Rosenthal Syndrome	1.4%
513	Mitochondrial Myopathies	1.4%
514	Carotid Artery Thrombosis	1.4%
515	Anisocoria	1.4%
516	Confusion	1.4%
517	Facial paralysis	1.4%
518	Lethargy	1.4%
519	Memory Disorders	1.4%
520	Muscle Cramp	1.4%
521	Perceptual Disorders	1.4%
522	Psychomotor Disorders	1.4%
523	Tonic Pupil	1.4%
524	Eosinophilia-Myalgia Syndrome	1.4%
525	Anhedonia	1.4%
526	Disorientation	1.4%
527	Facial Paresis	1.4%
528	Memory Loss	1.4%
529	Hemisensory Neglect	1.4%
530	Dysacusis	1.4%
531	Sleep Bruxism	1.4%
532	Anencephaly	1.4%
533	Meningocele	1.4%
534	Muscular Atrophy	1.4%
535	Respiratory Paralysis	1.4%
536	Encephalocele	1.4%
537	Tetany	1.4%
538	Optic Nerve Glioma	1.4%
539	Carpal Tunnel Syndrome	1.4%
540	Alstrom Syndrome	1.4%
541	Acoustic Neuroma	1.4%
542	neurofibroma	1.4%
543	Sciatica	1.3%
544	Hematoma, Subdural	1.3%
545	Hematoma, Epidural, Cranial	1.3%
546	Amyloid Neuropathies, Familial	1.3%
547	Acromegaly	1.2%
548	Sciatic Neuropathy	1.2%
549	Ulnar Neuropathies	1.2%
550	Lesion of Sciatic Nerve	1.2%
551	Ulnar Neuritis	1.2%
552	Radial nerve compression	1.2%
553	Radial Tunnel Syndrome	1.2%
554	Peroneal Neuropathies	1.2%
555	Radial Neuropathy	1.2%
556	Median Neuropathy	1.2%
557	Sciatic Nerve Palsy	1.2%
558	Femoral Neuropathy	1.2%
559	Tibial Neuropathy	1.2%
560	Ulnar Nerve Palsy	1.2%
561	Postural Orthostatic Tachycardia Syndrome	1.2%
562	Radial nerve palsy	1.2%
563	Cerebral Amyloid Angiopathy	1.2%
564	Sinus Thrombosis, Intracranial	1.2%
565	Duane Retraction Syndrome	1.2%
566	Consciousness Disorders	1.2%
567	Mental Retardation	1.2%
568	Muscle Weakness	1.2%
569	Depressed Level of Consciousness	1.2%
570	Mental deficiency	1.2%
571	Intellectual Disability	1.2%
572	Mobius Syndrome	1.2%
573	Bell Palsy	1.2%
574	Catatonia	1.2%
575	Herpes Zoster Oticus	1.2%
576	Familial Periodic Paralysis	1.2%
577	Aphonia	1.2%
578	Sleep Deprivation	1.2%
579	Dysphonia	1.2%
580	Galactosemias	1.1%
581	Urea Cycle Disorders, Inborn	1.1%
582	Tyrosinemias	1.1%
583	Cubital Tunnel Syndrome	1.1%
584	Fabry Disease	1%
585	Myalgia	1%
586	Hematoma, Subdural, Intracranial	1%
587	Hematoma, Subdural, Chronic	1%
588	Hematoma, Subdural, Acute	1%
589	Neuronal Ceroid-Lipofuscinoses	1%
590	Classical Lissencephalies and Subcortical Band Heterotopias	1%
591	Cavernous Sinus Thrombosis	1%
592	Sagittal Sinus Thrombosis	1%
593	Thoracic Outlet Syndrome	1%
594	Menkes Kinky Hair Syndrome	1%
595	Esotropia	1%
596	Exotropia	1%
597	Hypotension, Orthostatic	1%
598	Sleep Apnea Syndromes	1%
599	Polymyositis	1%
600	Post-Exercise Hypotension	1%
601	Homocystinuria	1%
602	Disorders of Excessive Somnolence	1%
603	Sleep Initiation and Maintenance Disorders	1%
604	Night Terrors	1%
605	Somnambulism	1%
606	Trigeminal Nerve Disorder	1%
607	Transient Insomnia	1%
608	Sleep Paralysis	1%
609	Chronic Insomnia	1%
610	REM Sleep Behavior Disorder	1%
611	Hypersomnia	1%
612	Dermal Sinus	1%
613	Dysgeusia	1%
614	Formication	1%
615	Hyperalgesia	1%
616	Hyperesthesia	1%
617	Hypesthesia	1%
618	Language Disorders	1%
619	Numbness	1%
620	Paresthesia	1%
621	Paraparesis, Spastic	1%
622	Spina Bifida Cystica	1%
623	Trismus	1%
624	Spina Bifida Occulta	1%
625	Epilepsia Partialis Continua	1%
626	Hypogeusia	1%
627	Meningeal Carcinomatosis	1%
628	Brown-Sequard Syndrome	1%
629	Lissencephaly	1%
630	Polymicrogyria	1%
631	Pachygyria	1%
632	Schizencephaly	1%
633	Lockjaw	1%
634	Allodynia	1%
635	Lead Poisoning, Nervous System, Childhood	1%
636	Lead Poisoning, Nervous System, Adult	1%
637	Periventricular Nodular Heterotopia	1%
638	Ageusia	1%
639	Leigh Disease	1%
640	Aicardi's syndrome	0.9%
641	Hoarseness	0.9%
642	Cockayne Syndrome	0.9%
643	Prolactinoma	0.9%
644	Growth Hormone-Secreting Pituitary Adenoma	0.9%
645	Alcohol Withdrawal Delirium	0.9%
646	Nelson Syndrome	0.9%
647	Eye Injuries	0.8%
648	Muscular Dystrophy	0.8%
649	Congenital nystagmus	0.8%
650	Orbital Myositis	0.8%
651	Diplopia	0.8%
652	Muscle Rigidity	0.8%
653	Muscle Spasticity	0.8%
654	Scotoma	0.8%
655	Photophobia	0.8%
656	Cogwheel Rigidity	0.8%
657	Hemifacial Spasm	0.8%
658	Amaurosis	0.8%
659	Blindness	0.8%
660	Nuchal Rigidity	0.8%
661	Holoprosencephaly	0.8%
662	Pyomyositis	0.8%
663	Agnosia	0.8%
664	Apraxias	0.8%
665	Hallucinations	0.8%
666	Hemianopsia	0.8%
667	Hyperacusis	0.8%
668	Tinnitus	0.8%
669	Visual Agnosia	0.8%
670	Anosognosia	0.8%
671	Wernicke-Korsakoff Syndrome	0.8%
672	Phonophobia	0.8%
673	Hearing Loss	0.8%
674	Optic Atrophy, Hereditary, Leber	0.8%
675	Polyradiculopathy	0.8%
676	Sarcopenia	0.8%
677	Alexia	0.8%
678	Dyslexia	0.8%
679	Zellweger Syndrome	0.8%
680	Kearns-Sayre syndrome	0.7%
681	Carbamoyl-Phosphate Synthase I Deficiency Disease	0.7%
682	Amnesia	0.7%
683	Delirium	0.7%
684	Dissociative Amnesia	0.7%
685	Color blindness	0.7%
686	Global Amnesia	0.7%
687	Cri-du-Chat Syndrome	0.7%
688	Down Syndrome	0.7%
689	Trisomy 21	0.7%
690	POEMS Syndrome	0.7%
691	Neurofibrosarcoma	0.7%
692	Meningioma	0.7%
693	Williams Syndrome	0.7%
694	Microcephaly	0.7%
695	Macrocephaly	0.7%
696	Hypokalemic periodic paralysis	0.7%
697	Porencephaly	0.7%
698	Glycogen storage disease type II	0.7%
699	Sleep Apnea, Obstructive	0.6%
700	Sleep Apnea, Central	0.6%
701	Narcolepsy	0.6%
702	Trigeminal Neuralgia	0.6%
703	Kleine-Levin Syndrome	0.6%
704	Agraphia	0.6%
705	Anomia	0.6%
706	Cluttering	0.6%
707	Language Development Disorders	0.6%
708	Speech Disorders	0.6%
709	Syncope	0.6%
710	Stupor	0.6%
711	Dysgraphia	0.6%
712	Presyncope	0.6%
713	Dyslalia	0.6%
714	Prader-Willi Syndrome	0.6%
715	Phantom pain	0.6%
716	Phantom Limb Pain	0.6%
717	Eye Burns	0.5%
718	Welander Distal Myopathy	0.5%
719	Amaurosis Fugax	0.5%
720	Blindness, Cortical	0.5%
721	Dyscalculia	0.5%
722	Rett Syndrome	0.5%
723	Deafness	0.5%
724	Hearing Loss, Sudden	0.5%
725	Gerstmann Syndrome	0.5%
726	Hearing Loss, Bilateral	0.5%
727	Hearing Loss, High-Frequency	0.5%
728	Hearing Loss, Mixed Conductive-Sensorineural	0.5%
729	Prosopagnosia	0.5%
730	Apraxia, Ideomotor	0.5%
731	Charles Bonnet Syndrome	0.5%
732	Hearing Loss, Unilateral	0.5%
733	Complete Hearing Loss	0.5%
734	Alien Hand Syndrome	0.5%
735	Deaf Mutism	0.5%
736	Gaucher Disease	0.5%
737	Rubinstein-Taybi Syndrome	0.5%
738	Cataplexy	0.5%
739	Aphasia	0.5%
740	Articulation Disorders	0.5%
741	Echolalia	0.5%
742	Stuttering	0.5%
743	Dysphasia	0.5%
744	Dermatomyositis	0.5%
745	Corneal Scar	0.5%
746	Muscular Dystrophy, Duchenne	0.5%
747	Retrograde amnesia	0.5%
748	Amnesia, Anterograde	0.5%
749	Tay-Sachs Disease	0.4%
750	Niemann-Pick Disease, Type C	0.4%
751	Mutism	0.4%
752	Selective Mutism	0.4%
753	Fragile X Syndrome	0.4%
754	Dysarthria	0.4%
755	Corneal Perforation	0.3%
756	Alexia, Pure	0.3%
757	Mucopolysaccharidosis II	0.3%

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