MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Mucoepidermoid Carcinoma

(UMLS:C0206694)

Definition:: A tumor of both low- and high-grade malignancy. The low-grade grow slowly, appear in any age group, and are readily cured by excision. The high-grade behave aggressively, widely infiltrate the salivary gland and produce lymph node and distant metastases. Mucoepidermoid carcinomas account for about 21% of the malignant tumors of the parotid gland and 10% of the sublingual gland. They are the most common malignant tumor of the parotid. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p575; Holland et al., Cancer Medicine, 3d ed, p1240)
UMLS ID:: C0206694
MeSH ID:: D018277

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.470.200.025.340|C04.557.470.590.340

Synonym(s)

Mucoepidermoid Carcinoma

Mucoepidermoid carcinoma

mucoepidermoid carcinoma

Associated Drug(s)

	Name	Number of Reports	Data Source
1	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	FAERS: 3	US FAERS
2	Docetaxel	FAERS: 1	US FAERS
3	Fingolimod Hydrochloride	FAERS: 1	US FAERS
4	HhAntag691	FAERS: 1	US FAERS
5	Letrozole	FAERS: 1	US FAERS
6	Vemurafenib	FAERS: 1	US FAERS
7	tofacitinib	FAERS: 1	US FAERS
8	Busulfan		OFFSIDES
9	Chloramphenicol		OFFSIDES
10	Cytarabine		OFFSIDES
11	Dactinomycin		OFFSIDES
12	Daunorubicin		OFFSIDES
13	Etoposide		OFFSIDES
14	Maraviroc		OFFSIDES
15	Modafinil		OFFSIDES
16	Phenytoin		OFFSIDES
17	Tenofovir		OFFSIDES
18	Thioguanine		OFFSIDES
19	cefuroxime axetil		OFFSIDES
20	pimecrolimus		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Cystadenocarcinoma	65.6%
2	Cystadenoma	52.2%
3	Basal cell carcinoma	49%
4	Carcinoma, Papillary	49%
5	Squamous cell carcinoma	49%
6	Carcinoma, Basal Cell	49%
7	Adenoid Cystic Carcinoma	44.1%
8	Adenocarcinoma, Clear Cell	44.1%
9	Cholangiocarcinoma	44.1%
10	Pseudomyxoma Peritonei	43.3%
11	Adenoma	41.6%
12	Mesothelioma	39.4%
13	Carcinoma in Situ	39%
14	Carcinoma, Transitional Cell	39%
15	Carcinoma, Large Cell	39%
16	Carcinoma, Small Cell	39%
17	Neoplasms, Neuroepithelial	38.5%
18	Gliomatosis cerebri	38.5%
19	Carcinoma, Lobular	38.4%
20	Carcinoma, Ehrlich Tumor	37.9%
21	Carcinoma, Lewis Lung	37.9%
22	Carcinoid Tumor	36%
23	Bowen's Disease	34.3%
24	Klatskin Tumor	34%
25	leukemia	31.5%
26	Neoplasms, Germ Cell and Embryonal	31.5%
27	Germ Cell Cancer	31.5%
28	Choriocarcinoma	30.9%
29	Malignant Carcinoid Syndrome	27.9%
30	Cervical Intraepithelial Neoplasia	27.1%
31	Neuroectodermal Tumors	26.9%
32	Papilloma	26.2%
33	Papillomatosis	26.2%
34	Adenomatosis, Pulmonary	26.2%
35	Adenomatous Polyps	26.2%
36	Adenoma, Acidophil	25.2%
37	Ganglioneuroma	25.2%
38	Glioma	25.2%
39	Malignant Glioma	25.2%
40	Adenofibroma	24.4%
41	Fibroadenoma	24.4%
42	Acanthoma	24.3%
43	Histiocytic Disorders, Malignant	23.7%
44	Medulloblastoma	23.4%
45	Carcinoma	22.7%
46	Epithelioma	22.7%
47	Carcinosarcoma	21.9%
48	Hemangiosarcoma	21.9%
49	lymphangiosarcoma	21.9%
50	Carcinoma, Pancreatic Ductal	20.3%
51	Carcinoid Heart Disease	20.3%
52	melanoma	20.3%
53	Hamartoma	20.2%
54	Neoplasms, Hormone-Dependent	20.2%
55	Neoplasms, Multiple Primary	20.2%
56	Paraneoplastic Syndromes	20.2%
57	Precancerous Conditions	20.2%
58	Neoplasms, Second Primary	20.2%
59	Adrenocortical carcinoma	20.1%
60	Meningioma	19.2%
61	Lymphoma	18.9%
62	Astrocytoma	18.7%
63	Ependymoma	18.7%
64	oligodendroglioma	18.7%
65	Ganglioglioma	18.7%
66	gliosarcoma	18.7%
67	Anaplastic astrocytoma	18.7%
68	Anaplastic Oligodendroglioma	18.7%
69	Carcinoma 256, Walker	18%
70	Composite Lymphoma	17.9%
71	Ameloblastoma	17.8%
72	Angiokeratoma	17.8%
73	Chordoma	17.8%
74	Hemangioma	17.8%
75	hemangiopericytoma	17.8%
76	Lymphangioma	17.8%
77	Mesenchymoma	17.8%
78	Nevus	17.8%
79	Teratoma	17.8%
80	Hepatoblastoma	17.8%
81	Mixed Tumor, Mullerian	17.8%
82	Germinoma	17.8%
83	Teratocarcinoma	17.8%
84	Angiofibroma	17.8%
85	Sarcoma	17.8%
86	Renal Cell Carcinoma	17.6%
87	Papillary Renal Cell Carcinoma	17.6%
88	Leukemia, Plasma Cell	17.5%
89	Carcinoma, Endometrioid	17.3%
90	Trophoblastic Neoplasms	17.3%
91	Leukemia, Experimental	17.2%
92	Chondrosarcoma	16.9%
93	Craniopharyngioma	16.9%
94	leiomyosarcoma	16.9%
95	liposarcoma	16.9%
96	synovial sarcoma	16.9%
97	Neuroectodermal Tumor, Melanotic	16.9%
98	Angiomyolipoma	16.9%
99	Clear Cell Sarcoma of Soft Tissue	16.9%
100	Alveolar Soft Part Sarcoma	16.9%
101	Neuroendocrine Tumors	16.9%
102	Sarcoma, Myeloid	16.9%
103	Mucoepidermoid Carcinoma	16.8%
104	Dermoid Cyst	16.5%
105	Basal Cell Nevus Syndrome	16.3%
106	Carcinoma, Ovarian Epithelial	16.1%
107	Retinoblastoma	15.6%
108	Glioblastoma	15.5%
109	Neuroblastoma	15.5%
110	Glioblastoma Multiforme	15.5%
111	Cyst	15.3%
112	Neoplastic Processes	15.3%
113	Neoplastic Syndromes, Hereditary	15.3%
114	Pregnancy Complications, Neoplastic	15.3%
115	Vipoma	15.2%
116	Hepatocellular Adenoma	15.2%
117	Neoplasms, Experimental	15%
118	Adenocarcinoma	15%
119	Melanoma, Experimental	14.8%
120	Gastrinoma	14.8%
121	Glucagonoma	14.8%
122	Leukemia, Radiation-Induced	14.5%
123	Fibrosarcoma	14.4%
124	Osteosarcoma	14.4%
125	Neurilemmoma	14.3%
126	Hutchinson's Melanotic Freckle	14.3%
127	Melanoma, Amelanotic	14.3%
128	Ganglioneuroblastoma	13.9%
129	Nasopharyngeal carcinoma	13.7%
130	Plasmacytoma	13.5%
131	Malignant histiocytosis	13.4%
132	Histiocytic sarcoma	13.4%
133	Malignant Fibrous Histiocytoma	13.2%
134	Sarcoma, Experimental	13.1%
135	Thymoma	13%
136	Leukemia L1210	13%
137	Leukemia P388	13%
138	Prolactinoma	12.9%
139	Growth Hormone-Secreting Pituitary Adenoma	12.9%
140	Endometrial Stromal Sarcoma	12.8%
141	Neoplasms, Radiation-Induced	12%
142	Paraganglioma	12%
143	Rhabdomyosarcoma	12%
144	Giant Cell Tumor of Bone	12%
145	Multiple Endocrine Neoplasia	11.9%
146	Lymphangioleiomyomatosis	11.3%
147	Phyllodes Tumor	11.2%
148	Dysgerminoma	11.2%
149	Hemangioendothelioma	11.2%
150	Lipoma	11.2%
151	Myoma	11.2%
152	Myxoma	11.2%
153	Neuroma	11.2%
154	Seminoma	11.2%
155	Angiolipoma	11.2%
156	Myelolipoma	11.2%
157	Neoplasms, Bone Tissue	11.2%
158	Neoplasms, Fibrous Tissue	11.2%
159	Smooth Muscle Tumor	11.2%
160	Desmoplastic Small Round Cell Tumor	11.2%
161	Chondroma	11.2%
162	Enchondroma	11.2%
163	Dermatofibrosarcoma	10.7%
164	Dermatofibrosarcoma Protuberans	10.7%
165	Hodgkin Disease	10.7%
166	Lymphoma, Non-Hodgkin	10.7%
167	Abdominal Neoplasms	10.5%
168	Erythroplasia	10.5%
169	Follicular cyst	10.5%
170	Head and Neck Neoplasms	10.5%
171	Mucocele	10.5%
172	Pilonidal Cyst	10.5%
173	Soft Tissue Neoplasms	10.5%
174	Thoracic Neoplasms	10.5%
175	Thyroglossal Cyst	10.5%
176	Synovial Cyst	10.5%
177	Aberrant Crypt Foci	10.5%
178	Sarcoma 180	10.5%
179	Paraneoplastic Encephalomyelitis	10.1%
180	Mammary Neoplasms, Experimental	9.9%
181	Pheochromocytoma	9.5%
182	Alveolar rhabdomyosarcoma	9.5%
183	Neurofibrosarcoma	9.5%
184	Nephroblastoma	9.3%
185	Lymphomatoid Granulomatosis	9.2%
186	Optic Nerve Glioma	9.1%
187	insulinoma	9%
188	Primary amyloidosis	9%
189	Tuberous Sclerosis	8.7%
190	Adenomatous Polyposis Coli	8.5%
191	Leukemia, Myelomonocytic, Chronic	8.4%
192	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	8.4%
193	Digestive System Neoplasms	8.3%
194	Endocrine Gland Neoplasms	8.3%
195	Eye Neoplasms	8.3%
196	Nervous System Neoplasms	8.3%
197	Bone neoplasms	8%
198	Leukoplakia	8%
199	Lymphocele	8%
200	Pancreatic Cyst	8%
201	Skin Neoplasms	8%
202	Hematologic Neoplasms	8%
203	fibroma	8%
204	Fibromatosis	8%
205	Osteoblastoma	8%
206	Osteoma	8%
207	Rhabdomyoma	8%
208	Chondromatosis	8%
209	Hemangioblastoma	8%
210	Lymphoma, Extranodal NK-T-Cell	8%
211	Barrett Esophagus	7.9%
212	Breast Cyst	7.9%
213	Actinic keratosis	7.9%
214	Mediastinal Cyst	7.9%
215	Neoplasm Invasiveness	7.9%
216	Neoplasm Metastasis	7.9%
217	Neoplasm Recurrence, Local	7.9%
218	Parovarian Cyst	7.9%
219	Pericardial Cyst	7.9%
220	Splenic Neoplasms	7.9%
221	Thymic Cyst	7.9%
222	Carcinogenesis	7.9%
223	Myxoid cyst	7.9%
224	Metastasis	7.9%
225	Mesoblastic Nephroma	7.6%
226	Acoustic Neuroma	7.1%
227	Hydatidiform Mole	7%
228	Mastocytosis	6.9%
229	Sturge-Weber Syndrome	6.9%
230	Gastrointestinal Stromal Tumors	6.8%
231	Hemangioma, Cavernous	6.8%
232	Multiple Endocrine Neoplasia Type 1	6.8%
233	Leukemia, T-Cell	6.8%
234	Leukemia, B-Cell	6.8%
235	Waldenstrom Macroglobulinemia	6.7%
236	Multiple Myeloma	6.7%
237	neurofibroma	6.7%
238	Lymphoma, Follicular	6.7%
239	T-Cell Lymphoma	6.7%
240	Mantle cell lymphoma	6.7%
241	Fibromatosis, Aggressive	6.4%
242	Fibromatosis, Abdominal	6.4%
243	Corpus Luteum Cyst	6.2%
244	Ovarian Cysts	6.2%
245	Parathyroid Neoplasms	6.2%
246	Peritoneal Neoplasms	6.2%
247	Thyroid Neoplasm	6.2%
248	Thyroid carcinoma	6.2%
249	Liver Neoplasms, Experimental	6.1%
250	Mastocytoma	6%
251	Mastocytosis, Systemic	6%
252	Leukemia, Myeloid, Chronic-Phase	6%
253	Retroperitoneal Neoplasms	5.9%
254	granulosa cell tumor	5.6%
255	Pancreatic Neoplasm	5.3%
256	Choledochal Cyst	5.3%
257	Peutz-Jeghers Syndrome	5.2%
258	Tracheal Neoplasms	5%
259	Leukoplakia, Oral	4.9%
260	Paraneoplastic Cerebellar Degeneration	4.9%
261	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	4.8%
262	Leukemia, Large Granular Lymphocytic	4.8%
263	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	4.8%
264	Lymphoma, T-Cell, Cutaneous	4.8%
265	Lymphoma, AIDS-Related	4.8%
266	Enteropathy-Associated T-Cell Lymphoma	4.8%
267	Primary Effusion Lymphoma	4.8%
268	Mouth Neoplasms	4.6%
269	Central Nervous System Neoplasms	4.6%
270	Vascular Neoplasms	4.6%
271	Thymus Neoplasms	4.6%
272	Genital Neoplasms, Female	4.5%
273	Pancreatic Pseudocyst	4.5%
274	Lymphatic Metastasis	4.5%
275	Neoplasms, Unknown Primary	4.5%
276	Leukemic Infiltration	4.5%
277	Breast Neoplasms, Male	4.5%
278	Neoplasm Micrometastasis	4.5%
279	Triple Negative Breast Neoplasms	4.5%
280	Leydig Cell Tumor	4.2%
281	Esophageal Neoplasms	4.2%
282	Limbic Encephalitis	4.2%
283	Denys-Drash Syndrome	4.1%
284	Dupuytren Contracture	3.9%
285	Urticaria Pigmentosa	3.9%
286	Mycosis Fungoides	3.8%
287	Lymphomatoid Papulosis	3.8%
288	Plasmablastic lymphoma	3.8%
289	Thyroid Nodule	3.8%
290	Lambert-Eaton Myasthenic Syndrome	3.7%
291	Testicular Neoplasms	3.7%
292	Adrenal Gland Neoplasms	3.7%
293	Gastrointestinal Neoplasms	3.7%
294	Genital Neoplasms, Male	3.7%
295	Liver neoplasms	3.7%
296	Uveal Neoplasms	3.7%
297	Urologic Neoplasms	3.7%
298	Sebaceous Gland Neoplasms	3.6%
299	Spinal Neoplasms	3.6%
300	Bone Marrow Neoplasms	3.6%
301	Polycystic Ovary Syndrome	3.5%
302	Burkitt Lymphoma	3.4%
303	Opsoclonus-Myoclonus Syndrome	3.3%
304	Xeroderma Pigmentosum	3.2%
305	Myelitis, Transverse	2.9%
306	Meningeal Neoplasms	2.8%
307	Sezary Syndrome	2.8%
308	Nose Neoplasms	2.6%
309	ovarian neoplasm	2.6%
310	Palatal Neoplasms	2.4%
311	Pituitary Adenoma	2.4%
312	Pituitary Neoplasms	2.4%
313	Ear Neoplasms	2.3%
314	Eyelid Neoplasms	2.3%
315	Lung Neoplasms	2.3%
316	Pleural Neoplasms	2.3%
317	Cell Transformation, Viral	2.3%
318	Brain Neoplasms	2.3%
319	Salivary Gland Neoplasms	2.3%
320	Spinal Cord Neoplasms	2.3%
321	Tongue Neoplasms	2.3%
322	Uterine Neoplasms	2.3%
323	Vaginal Neoplasms	2.3%
324	Vulvar Neoplasms	2.3%
325	Uterine Cancer	2.3%
326	Fallopian Tube Neoplasms	2.2%
327	Zollinger-Ellison syndrome	2%
328	Meningeal Carcinomatosis	2%
329	Pharyngeal Neoplasms	2%
330	Central Nervous System Cysts	1.9%
331	Bile Duct Neoplasms	1.9%
332	gallbladder neoplasm	1.9%
333	Intestinal Neoplasms	1.9%
334	Penile Neoplasms	1.9%
335	Prostatic Neoplasms	1.9%
336	Stomach Neoplasms	1.9%
337	Polycythemia Vera	1.9%
338	Laryngeal neoplasm	1.7%
339	Bronchial Neoplasms	1.6%
340	Bladder Neoplasm	1.6%
341	Kidney Neoplasm	1.6%
342	Ureteral Neoplasms	1.6%
343	Urethral Neoplasms	1.6%
344	Multiple Pulmonary Nodules	1.6%
345	Supratentorial Neoplasms	1.6%
346	Endometrial Neoplasms	1.6%
347	Hypopharyngeal Neoplasms	1.4%
348	Pleural Effusion, Malignant	1.4%
349	Hypopharyngeal Cancer	1.4%
350	Parotid Neoplasms	1.3%
351	Prostatic Neoplasms, Castration-Resistant	1.3%
352	Nelson Syndrome	1.3%
353	Brain Stem Neoplasms	1.3%
354	Cecal Neoplasms	1.1%
355	Duodenal Neoplasms	1.1%
356	Choroid Plexus Papilloma	1.1%
357	Tonsillar Neoplasms	1.1%
358	Cerebellar Neoplasms	1.1%
359	Nasopharyngeal Neoplasms	1%
360	Colorectal Neoplasms	1%
361	Radicular Cyst	0.9%
362	Paranasal Sinus Neoplasms	0.9%
363	Appendiceal Neoplasms	0.9%
364	Colonic Neoplasms	0.9%
365	Rectal Neoplasms	0.9%
366	Maxillary Sinus Neoplasms	0.7%
367	Anus Neoplasms	0.7%
368	Sigmoid Neoplasms	0.7%

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