MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Carcinogenesis

(UMLS:C0596263)

Definition:: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
UMLS ID:: C0596263
MeSH ID:: D063646

Classification 1:

Name:

Neoplasms
MeSH Tree Number(s):: C04.697.098

Classification 2:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.550.727.098

Synonym(s)

Carcinogenesis

Cancer Induction

carcinogenesis

Associated Drug(s)

	Name	Reference(s)	Data Source
1	1,3-butadiene	30990016	CTD
2	Benzo(a)pyrene	28279692	CTD
3	Cyproterone Acetate	1347714	CTD
4	Diethylnitrosamine	283272	CTD
5	N-Nitrosopyrrolidine	6268293	CTD
6	N-nitroso(di-n-propyl)amine	283272	CTD
7	N-nitrosoperhydroazepine	View details 283272 4298999 6268293 6515660 6593491	CTD
8	N-nitrosopiperidine	6268293	CTD
9	Pentachlorophenol	25608107	CTD
10	Phosphates	26285136	CTD
11	chromium hexavalent ion	28596144	CTD
12	dimethoxon	28718371	CTD
13	geraniol	8169651	CTD
14	lemon oil	8169651	CTD
15	norathyriol	22084399	CTD
16	perillyl alcohol	8169651	CTD
17	plastochromanol 8	8169651	CTD
18	usnic acid	27497765	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Neoplasm Invasiveness	44.8%
2	Neoplasm Metastasis	44.8%
3	Neoplasm Recurrence, Local	44.8%
4	Metastasis	44.8%
5	Lymphatic Metastasis	32.8%
6	Neoplasms, Unknown Primary	32.8%
7	Leukemic Infiltration	32.8%
8	Neoplasm Micrometastasis	32.8%
9	Polydipsia	21.1%
10	Ascites	20.9%
11	Fibrosis	20.9%
12	Gliosis	20.9%
13	Growth Disorders	20.9%
14	Hemorrhage	20.9%
15	Hyperbilirubinemia	20.9%
16	Hyperplasia	20.9%
17	Hypomenorrhea	20.9%
18	Inflammation	20.9%
19	Intraoperative Complications	20.9%
20	Ischemia	20.9%
21	Lithiasis	20.9%
22	Malacoplakia	20.9%
23	Menstruation Disturbances	20.9%
24	Metaplasia	20.9%
25	Nerve Degeneration	20.9%
26	Ochronosis	20.9%
27	Polymenorrhea	20.9%
28	Postoperative Complications	20.9%
29	Sclerosis	20.9%
30	Shock	20.9%
31	Ulcer	20.9%
32	Hyperammonemia	20.9%
33	Hyperamylasemia	20.9%
34	Teratogenesis	20.9%
35	Cardiac Death	20.9%
36	Hypovolemia	20.9%
37	Hyperuricemia	20.9%
38	Leukoaraiosis	20.9%
39	Dysbacteriosis	20.9%
40	Delayed Graft Function	20.9%
41	Cirrhosis	20.9%
42	Neointima	20.9%
43	Dysbiosis	20.9%
44	Infarction	20.3%
45	Postoperative Hemorrhage	20.3%
46	Shock, Hemorrhagic	20.3%
47	Systemic Inflammatory Response Syndrome	20.3%
48	Vascular Remodeling	16.9%
49	Cyst	16.4%
50	Extravasation of Diagnostic and Therapeutic Materials	16.4%
51	Necrosis	15.8%
52	Granulomatosis, Orofacial	15.8%
53	Pigmentation Disorders	15.8%
54	Respiratory Aspiration	15.8%
55	Acantholysis	15.5%
56	Chromosome Aberrations	15.5%
57	Dehydration	15.5%
58	Granuloma	15.5%
59	Leukocytosis	15.5%
60	Pleocytosis	15.5%
61	Sudden infant death syndrome	15%
62	Hamartoma	14.6%
63	Neoplasms, Hormone-Dependent	14.6%
64	Neoplasms, Multiple Primary	14.6%
65	Paraneoplastic Syndromes	14.6%
66	Precancerous Conditions	14.6%
67	Neoplasms, Second Primary	14.6%
68	Menorrhagia	14%
69	Acute Disease	13.6%
70	Acute-Phase Reaction	13.6%
71	Amenorrhea	13.6%
72	Chronic disease	13.6%
73	Critical Illness	13.6%
74	Sudden death	13.6%
75	Fat necrosis	13.6%
76	Gangrene	13.6%
77	Graft Occlusion, Vascular	13.6%
78	Granuloma, Plasma Cell	13.6%
79	Hematoma	13.6%
80	Iatrogenic Disease	13.6%
81	Multiple Organ Failure	13.6%
82	Oligomenorrhea	13.6%
83	Premenstrual syndrome	13.6%
84	Recurrence	13.6%
85	Retrograde Degeneration	13.6%
86	Retroperitoneal fibrosis	13.6%
87	Serositis	13.6%
88	Subcutaneous Emphysema	13.6%
89	Surgical Wound Dehiscence	13.6%
90	Syndrome	13.6%
91	Wallerian Degeneration	13.6%
92	Pyogenic granuloma	13.6%
93	Exsanguination	13.6%
94	Disease Progression	13.6%
95	Seroma	13.6%
96	Premenstrual Tension	13.6%
97	Delayed Emergence from Anesthesia	13.6%
98	Infant Death	13.6%
99	Anastomotic Leak	13.6%
100	Intraoperative Awareness	13.6%
101	Incisional hernia	13.6%
102	Chromosomal Instability	13.6%
103	jaundice	13.6%
104	Genomic Instability	12.9%
105	Pain, Postoperative	12.6%
106	Leukoplakia	12.3%
107	Signs and Symptoms	12.2%
108	Pathological Conditions, Anatomical	12.2%
109	Dysmenorrhea	12.1%
110	Failed Back Surgery Syndrome	12.1%
111	Azotemia	12.1%
112	Muscle Weakness	12%
113	Postoperative Nausea and Vomiting	12%
114	Carcinoma 256, Walker	11.8%
115	Eye Hemorrhage	11.3%
116	Carcinoma, Ehrlich Tumor	11.1%
117	Dermoid Cyst	11.1%
118	Carcinoma, Lewis Lung	11.1%
119	Endotoxic shock	11%
120	Septic Shock	11%
121	Toxic Shock Syndrome	11%
122	Hemoptysis	11%
123	Neoplastic Syndromes, Hereditary	10.9%
124	Pregnancy Complications, Neoplastic	10.9%
125	Multiple Endocrine Neoplasia	10.9%
126	Ecchymosis	10.8%
127	Petechiae	10.8%
128	Purpura	10.8%
129	Asphyxia	10.7%
130	Granuloma, Respiratory Tract	10.7%
131	Neoplasms, Experimental	10.7%
132	Shock, Traumatic	10.7%
133	Neoplasms, Neuroepithelial	10.7%
134	Gliomatosis cerebri	10.7%
135	Medulloblastoma	10.5%
136	Cardiotoxicity	10.4%
137	Disease susceptibility	10.3%
138	Fetal Death	10.3%
139	Foreign-Body Reaction	10.3%
140	Gastrointestinal Hemorrhage	10.3%
141	Hemarthrosis	10.3%
142	Hemoperitoneum	10.3%
143	Hemothorax	10.3%
144	Parovarian Cyst	10.3%
145	Postpericardiotomy Syndrome	10.3%
146	Prosthesis Failure	10.3%
147	Reperfusion Injury	10.3%
148	Injection Site Reaction	10.3%
149	Retrobulbar Hemorrhage	10.3%
150	Aseptic Necrosis of Bone	10.3%
151	Peritoneal Fibrosis	10.3%
152	Neurogenic Inflammation	10.3%
153	Perinatal death	10.3%
154	Infusion site reaction	10.3%
155	Nephrogenic Fibrosing Dermopathy	10.3%
156	Corneal Endothelial Cell Loss	10.3%
157	Encapsulating Peritoneal Sclerosis	10.3%
158	Vasoplegia	10.3%
159	Suppuration	10.3%
160	Nephrogenic Systemic Fibrosis	10.3%
161	Sinus Arrhythmia	10.2%
162	Atrial Fibrillation	10.2%
163	Atrial Flutter	10.2%
164	Dental Pulp Necrosis	10.2%
165	Granuloma, Foreign-Body	10.2%
166	Mediastinal Emphysema	10.2%
167	Surgical Wound Infection	10.2%
168	Ventricular Fibrillation	10.2%
169	Ventricular Flutter	10.2%
170	Parasystole	10.2%
171	Neuroectodermal Tumors	10.2%
172	Paroxysmal atrial fibrillation	10.2%
173	Facies	10.2%
174	Bradycardia	10.2%
175	Embryo Loss	10.2%
176	Melanoma, Experimental	10.2%
177	Tissue Adhesions	10.1%
178	Hematoma, Epidural, Spinal	10.1%
179	Afferent Loop Syndrome	10.1%
180	Sex Chromosome Aberrations	10.1%
181	Short Bowel Syndrome	10.1%
182	Uterine hemorrhage	10.1%
183	No-Reflow Phenomenon	10.1%
184	Jaundice, Obstructive	10%
185	melanoma	9.9%
186	Chromosome Fragility	9.9%
187	Paraneoplastic Encephalomyelitis	9.7%
188	Trophoblastic Neoplasms	9.6%
189	Leukemia, Experimental	9.5%
190	Mammary Neoplasms, Experimental	9.5%
191	Abdominal Neoplasms	9.3%
192	Erythroplasia	9.3%
193	Follicular cyst	9.3%
194	Head and Neck Neoplasms	9.3%
195	leukemia	9.3%
196	Mucocele	9.3%
197	Neoplasms, Germ Cell and Embryonal	9.3%
198	Neoplasms, Glandular and Epithelial	9.3%
199	Pilonidal Cyst	9.3%
200	Soft Tissue Neoplasms	9.3%
201	Thoracic Neoplasms	9.3%
202	Thyroglossal Cyst	9.3%
203	Synovial Cyst	9.3%
204	Germ Cell Cancer	9.3%
205	Aberrant Crypt Foci	9.3%
206	Carcinosarcoma	9.2%
207	Hemangiosarcoma	9.2%
208	Leukemia L1210	9.2%
209	Leukemia P388	9.2%
210	lymphangiosarcoma	9.2%
211	Acanthoma	9.2%
212	Adenoma, Acidophil	9.2%
213	Ganglioneuroma	9.2%
214	Glioma	9.2%
215	Malignant Glioma	9.2%
216	Epistaxis	9.2%
217	Meningioma	9.1%
218	Carcinoid Tumor	8.9%
219	Neurilemmoma	8.9%
220	Hutchinson's Melanotic Freckle	8.9%
221	Melanoma, Amelanotic	8.9%
222	Sarcoma 180	8.8%
223	Sarcoma, Experimental	8.8%
224	Choriocarcinoma	8.5%
225	Carcinoma, Lobular	8.5%
226	Neoplasms, Radiation-Induced	8.5%
227	Astrocytoma	8.5%
228	Ependymoma	8.5%
229	oligodendroglioma	8.5%
230	Ganglioglioma	8.5%
231	gliosarcoma	8.5%
232	Anaplastic astrocytoma	8.5%
233	Anaplastic Oligodendroglioma	8.5%
234	Drowning	8.5%
235	Sick Sinus Syndrome	8.5%
236	Trisomy	8.5%
237	Leukoplakia, Oral	8.4%
238	Hematoma, Subdural, Spinal	8.4%
239	Basal cell carcinoma	8.3%
240	Carcinoma, Papillary	8.3%
241	Squamous cell carcinoma	8.3%
242	Chondrosarcoma	8.3%
243	Craniopharyngioma	8.3%
244	Cystadenoma	8.3%
245	leiomyosarcoma	8.3%
246	liposarcoma	8.3%
247	Mesothelioma	8.3%
248	synovial sarcoma	8.3%
249	Neuroectodermal Tumor, Melanotic	8.3%
250	Angiomyolipoma	8.3%
251	Clear Cell Sarcoma of Soft Tissue	8.3%
252	Alveolar Soft Part Sarcoma	8.3%
253	Neuroendocrine Tumors	8.3%
254	Sarcoma, Myeloid	8.3%
255	Carcinoma, Basal Cell	8.3%
256	Malignant Carcinoid Syndrome	8.3%
257	Fetal Growth Retardation	8.2%
258	DNA Degradation, Necrotic	8.2%
259	Aneuploidy	8.2%
260	Polyploidy	8.2%
261	Microsatellite Instability	8.2%
262	Glioblastoma	8.1%
263	Neuroblastoma	8.1%
264	Glioblastoma Multiforme	8.1%
265	Heart Block	8.1%
266	Tachycardia	8.1%
267	Tachyarrhythmia	8.1%
268	Cicatrix	8.1%
269	Multiple Endocrine Neoplasia Type 1	8.1%
270	Hematuria	8.1%
271	Granuloma Annulare	8.1%
272	Chromosome Breakage	8.1%
273	Brain Death	8%
274	Hematemesis	8%
275	Leukemia, Radiation-Induced	8%
276	Shock, Cardiogenic	8%
277	Ganglioneuroblastoma	8%
278	Purpura Fulminans	7.9%
279	Cystadenocarcinoma	7.9%
280	Fibrosarcoma	7.9%
281	Osteosarcoma	7.9%
282	Mucoepidermoid Carcinoma	7.9%
283	Cross Infection	7.7%
284	Hyphema	7.7%
285	Retinal Neovascularization	7.7%
286	Septicemia	7.7%
287	Vitreous Hemorrhage	7.7%
288	Sepsis	7.7%
289	Adenofibroma	7.7%
290	Fibroadenoma	7.7%
291	Malignant Fibrous Histiocytoma	7.7%
292	Abscess	7.6%
293	Empyema	7.6%
294	Femur Head Necrosis	7.6%
295	Fetal Resorption	7.6%
296	Peptic Ulcer Hemorrhage	7.6%
297	Sudden Cardiac Death	7.6%
298	Premenstrual Dysphoric Disorder	7.6%
299	Choroidal Neovascularization	7.6%
300	Primary Graft Dysfunction	7.6%
301	Dumping Syndrome	7.5%
302	Cicatrix, Hypertrophic	7.5%
303	Sinus Arrest, Cardiac	7.5%
304	Metrorrhagia	7.5%
305	Tuberous Sclerosis	7.4%
306	Bowen's Disease	7.4%
307	Paraganglioma	7.4%
308	Rhabdomyosarcoma	7.4%
309	Giant Cell Tumor of Bone	7.4%
310	Thymoma	7.4%
311	Hematoma, Subdural	7.3%
312	Hematoma, Epidural, Cranial	7.3%
313	Leukemia, Plasma Cell	7.3%
314	Digestive System Neoplasms	7.3%
315	Endocrine Gland Neoplasms	7.3%
316	Eye Neoplasms	7.3%
317	Nervous System Neoplasms	7.3%
318	Dermatofibrosarcoma	7.2%
319	Dermatofibrosarcoma Protuberans	7.2%
320	Bone neoplasms	7%
321	Lymphocele	7%
322	Pancreatic Cyst	7%
323	Skin Neoplasms	7%
324	Hematologic Neoplasms	7%
325	Retinoblastoma	7%
326	Pheochromocytoma	7%
327	Alveolar rhabdomyosarcoma	7%
328	Asthenia	7%
329	Body Temperature Changes	7%
330	Calculi	7%
331	Cyanosis	7%
332	Edema	7%
333	Failure to Thrive	7%
334	Fatigue	7%
335	Feminization	7%
336	Fetal Distress	7%
337	Hernia	7%
338	Hypertrophy	7%
339	Motion Sickness	7%
340	Nails, Malformed	7%
341	polyps	7%
342	Rupture, Spontaneous	7%
343	Signs and Symptoms, Digestive	7%
344	Signs and Symptoms, Respiratory	7%
345	Skin Manifestations	7%
346	Chills	7%
347	Lassitude	7%
348	Enterocele	7%
349	Atheroma	7%
350	Pseudophakia	7%
351	Urological Manifestations	7%
352	Stenosis	7%
353	Facial asymmetry	7%
354	Mobility Limitation	7%
355	Somnolence	7%
356	Plaque, Amyloid	7%
357	Plaque, Atherosclerotic	7%
358	Lymphomatoid Granulomatosis	6.9%
359	Barrett Esophagus	6.9%
360	Breast Cyst	6.9%
361	Histiocytic Disorders, Malignant	6.9%
362	Actinic keratosis	6.9%
363	Mediastinal Cyst	6.9%
364	Parathyroid Neoplasms	6.9%
365	Pericardial Cyst	6.9%
366	Peritoneal Neoplasms	6.9%
367	Splenic Neoplasms	6.9%
368	Thymic Cyst	6.9%
369	Thyroid Neoplasm	6.9%
370	Thyroid carcinoma	6.9%
371	Myxoid cyst	6.9%
372	Carcinoma, Pancreatic Ductal	6.9%
373	Giant Cell Epulis	6.9%
374	Adenoma	6.8%
375	Ameloblastoma	6.8%
376	Angiokeratoma	6.8%
377	Carcinoma	6.8%
378	Chordoma	6.8%
379	Hemangioma	6.8%
380	hemangiopericytoma	6.8%
381	Lymphangioma	6.8%
382	Mesenchymoma	6.8%
383	Nevus	6.8%
384	Retroperitoneal Neoplasms	6.8%
385	Teratoma	6.8%
386	Hepatoblastoma	6.8%
387	Mixed Tumor, Mullerian	6.8%
388	Germinoma	6.8%
389	Teratocarcinoma	6.8%
390	Angiofibroma	6.8%
391	Sarcoma	6.8%
392	Epithelioma	6.8%
393	Carcinoid Heart Disease	6.8%
394	Long QT Syndrome	6.7%
395	Composite Lymphoma	6.7%
396	Acoustic Neuroma	6.6%
397	Viremia	6.6%
398	Parasitemia	6.6%
399	Micronuclei, Chromosome-Defective	6.6%
400	Phantom pain	6.6%
401	Phantom Limb Pain	6.6%
402	Basal Cell Nevus Syndrome	6.5%
403	Vipoma	6.3%
404	Tracheal Neoplasms	6.3%
405	Hydatidiform Mole	6.2%
406	Liver Neoplasms, Experimental	6.2%
407	Retinal Hemorrhage	6.2%
408	Neurofibrosarcoma	6.1%
409	Choroid Hemorrhage	6.1%
410	Melena	6.1%
411	Nephroblastoma	6.1%
412	Paraneoplastic Cerebellar Degeneration	6.1%
413	Hematoma, Subdural, Intracranial	6.1%
414	Hematoma, Subdural, Chronic	6.1%
415	Hematoma, Subdural, Acute	6.1%
416	Postpartum Hemorrhage	6%
417	Gingival Hemorrhage	6%
418	Keloid	6%
419	Monosomy	6%
420	Tetraploidy	6%
421	Stillbirth	6%
422	Adams-Stokes Syndrome	6%
423	Atrioventricular Block	6%
424	Bundle-Branch Block	6%
425	Atrial Premature Complexes	6%
426	Sinoatrial Block	6%
427	Tachycardia, Paroxysmal	6%
428	Supraventricular tachycardia	6%
429	Tachycardia, Ventricular	6%
430	Tachycardia, Reciprocating	6%
431	Pancreatic Neoplasm	5.9%
432	Subarachnoid Hemorrhage	5.9%
433	Cerebral Hemorrhage	5.9%
434	Abdominal Pain	5.9%
435	Optic Nerve Glioma	5.9%
436	Subacute Combined Degeneration	5.8%
437	Thrombocytopenic purpura	5.8%
438	Eosinophilic Granuloma	5.7%
439	Endometrial Stromal Sarcoma	5.7%
440	Purpura, Hyperglobulinemic	5.7%
441	Adenocarcinoma	5.6%
442	Carcinoma in Situ	5.6%
443	Carcinoma, Transitional Cell	5.6%
444	Phyllodes Tumor	5.6%
445	Dysgerminoma	5.6%
446	Hemangioendothelioma	5.6%
447	Lipoma	5.6%
448	Myoma	5.6%
449	Myxoma	5.6%
450	Neuroma	5.6%
451	Papilloma	5.6%
452	Pseudomyxoma Peritonei	5.6%
453	Seminoma	5.6%
454	Papillomatosis	5.6%
455	Angiolipoma	5.6%
456	Myelolipoma	5.6%
457	Neoplasms, Bone Tissue	5.6%
458	Neoplasms, Fibrous Tissue	5.6%
459	Smooth Muscle Tumor	5.6%
460	Adenomatosis, Pulmonary	5.6%
461	Adenomatous Polyps	5.6%
462	Carcinoma, Large Cell	5.6%
463	Carcinoma, Small Cell	5.6%
464	Desmoplastic Small Round Cell Tumor	5.6%
465	Chondroma	5.6%
466	Enchondroma	5.6%
467	Thyroid Nodule	5.6%
468	Hepatocellular Adenoma	5.6%
469	insulinoma	5.5%
470	Lymphangioleiomyomatosis	5.5%
471	Lymphoma	5.5%
472	Eye Manifestations	5.5%
473	Neurologic Manifestations	5.5%
474	Corpus Luteum Cyst	5.4%
475	Ovarian Cysts	5.4%
476	Gastrinoma	5.4%
477	Glucagonoma	5.4%
478	Esophageal Neoplasms	5.3%
479	Cardiac Output, High	5.3%
480	Myocardial Stunning	5.3%
481	Reticulocytosis	5.3%
482	Low Cardiac Output Syndrome	5.3%
483	Airway Remodeling	5.3%
484	Limbic Encephalitis	5.2%
485	Mouth Neoplasms	5.2%
486	Central Nervous System Neoplasms	5.2%
487	Vascular Neoplasms	5.2%
488	Ventricular Remodeling	5.2%
489	Thymus Neoplasms	5.2%
490	Alopecia	5.1%
491	Intermittent Claudication	5.1%
492	Androgenetic Alopecia	5.1%
493	Bacteremia	5.1%
494	Cellulitis	5.1%
495	Genital Neoplasms, Female	5.1%
496	Pancreatic Pseudocyst	5.1%
497	Plasmacytoma	5.1%
498	Kernicterus	5.1%
499	Malignant histiocytosis	5%
500	Breast Neoplasms, Male	5%
501	Histiocytic sarcoma	5%
502	Triple Negative Breast Neoplasms	5%
503	Adenoid Cystic Carcinoma	5%
504	fibroma	5%
505	Fibromatosis	5%
506	Osteoblastoma	5%
507	Osteoma	5%
508	Rhabdomyoma	5%
509	Renal Colic	5%
510	Chondromatosis	5%
511	Adenocarcinoma, Clear Cell	5%
512	Cholangiocarcinoma	5%
513	Cervical Intraepithelial Neoplasia	5%
514	Hemangioblastoma	5%
515	Lymphoma, Extranodal NK-T-Cell	5%
516	Fungemia	5%
517	Adenomatous Polyposis Coli	5%
518	Romano-Ward Syndrome	4.9%
519	Tachycardia, Atrioventricular Nodal Reentry	4.9%
520	Tachycardia, Ectopic Atrial	4.9%
521	Tachycardia, Ectopic Junctional	4.9%
522	Sinus Tachycardia	4.9%
523	Torsades de Pointes	4.9%
524	Accelerated Idioventricular Rhythm	4.9%
525	Leydig Cell Tumor	4.8%
526	Eye pain	4.8%
527	Fibromatosis, Aggressive	4.7%
528	Fibromatosis, Abdominal	4.7%
529	Klatskin Tumor	4.7%
530	Prolactinoma	4.7%
531	Growth Hormone-Secreting Pituitary Adenoma	4.7%
532	Muscular Atrophy	4.7%
533	Purpura, Thrombotic Thrombocytopenic	4.7%
534	Lambert-Eaton Myasthenic Syndrome	4.6%
535	Testicular Neoplasms	4.6%
536	Choledochal Cyst	4.6%
537	Abdomen, Acute	4.6%
538	Anorexia	4.5%
539	Anoxia	4.5%
540	Constipation	4.5%
541	Diarrhea	4.5%
542	Dyspepsia	4.5%
543	Eructation	4.5%
544	Fever	4.5%
545	Flatulence	4.5%
546	Flushing	4.5%
547	Halitosis	4.5%
548	Heartburn	4.5%
549	Diaphragmatic Hernia	4.5%
550	Hiccough	4.5%
551	Hypercalciuria	4.5%
552	Hypercapnia	4.5%
553	Hyperphagia	4.5%
554	Intestinal Polyps	4.5%
555	Nausea	4.5%
556	Pallor	4.5%
557	Psychophysiologic Disorders	4.5%
558	Splenomegaly	4.5%
559	Vomiting	4.5%
560	Hypocapnia	4.5%
561	Dyschezia	4.5%
562	Hypoxia	4.5%
563	Hyperoxia	4.5%
564	Lower Urinary Tract Symptoms	4.5%
565	Hypoxemia	4.5%
566	Urinoma	4.5%
567	Endotoxemia	4.5%
568	Peutz-Jeghers Syndrome	4.5%
569	Granuloma, Laryngeal	4.4%
570	Myocardial Reperfusion Injury	4.3%
571	Mesoblastic Nephroma	4.3%
572	Adrenocortical carcinoma	4.2%
573	Meningeal Neoplasms	4.2%
574	Adrenal Gland Neoplasms	4.2%
575	Gastrointestinal Neoplasms	4.2%
576	Genital Neoplasms, Male	4.2%
577	Hypergammaglobulinemia	4.2%
578	Leukemia, Myelomonocytic, Chronic	4.2%
579	Liver neoplasms	4.2%
580	Uveal Neoplasms	4.2%
581	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	4.2%
582	Urologic Neoplasms	4.1%
583	Opsoclonus-Myoclonus Syndrome	4.1%
584	granulosa cell tumor	4.1%
585	Carcinoma, Ovarian Epithelial	4.1%
586	Diverticulum	4.1%
587	Sebaceous Gland Neoplasms	4.1%
588	Spinal Neoplasms	4.1%
589	Bone Marrow Neoplasms	4.1%
590	Diverticulosis	4.1%
591	Hodgkin Disease	4%
592	Lymphoma, Non-Hodgkin	4%
593	Polycystic Ovary Syndrome	4%
594	Palatal Neoplasms	3.9%
595	Nose Neoplasms	3.8%
596	Mastocytoma	3.8%
597	Meningeal Carcinomatosis	3.7%
598	Mastocytosis, Systemic	3.7%
599	Leukemia, Myeloid, Chronic-Phase	3.7%
600	Autoimmune thrombocytopenia	3.7%
601	Immune thrombocytopenic purpura	3.7%
602	Renal Cell Carcinoma	3.7%
603	Papillary Renal Cell Carcinoma	3.7%
604	Myelitis, Transverse	3.6%
605	Sarcopenia	3.6%
606	Philadelphia Chromosome	3.6%
607	Respiratory Tract Fistula	3.6%
608	Waterhouse-Friderichsen Syndrome	3.6%
609	Carcinoma, Endometrioid	3.5%
610	Denys-Drash Syndrome	3.5%
611	Apnea	3.4%
612	Cheyne-Stokes Respiration	3.4%
613	Decerebrate State	3.4%
614	Dyspnea	3.4%
615	Ear Neoplasms	3.4%
616	Eyelid Neoplasms	3.4%
617	Cardiomegaly	3.4%
618	Hemiparesis	3.4%
619	Hepatomegaly	3.4%
620	Hyperventilation	3.4%
621	Lung Neoplasms	3.4%
622	Meningism	3.4%
623	Mouth Breathing	3.4%
624	Paresis	3.4%
625	Pleural Neoplasms	3.4%
626	Pruritus	3.4%
627	Seizures	3.4%
628	Sensation Disorders	3.4%
629	Sneezing	3.4%
630	Spermatocele	3.4%
631	Erythema	3.4%
632	Oral Fistula	3.4%
633	Complex partial seizures	3.4%
634	Necrolytic Migratory Erythema	3.4%
635	Tachypnea	3.4%
636	Monoparesis	3.4%
637	Cutaneous Fistula	3.4%
638	Gait Disorders, Neurologic	3.4%
639	Neuromuscular Manifestations	3.4%
640	Cardiac Hypertrophy	3.4%
641	Mastocytosis	3.4%
642	Sturge-Weber Syndrome	3.4%
643	Edema, Cardiac	3.4%
644	Mental Fatigue	3.4%
645	Hirsutism	3.4%
646	Orthostatic intolerance	3.4%
647	Hypoventilation	3.4%
648	Back Pain	3.4%
649	Bulimia	3.4%
650	Neck Pain	3.4%
651	Chest Pain	3.4%
652	Colonic Polyps	3.4%
653	Dizziness	3.4%
654	Dysuria	3.4%
655	Facial Pain	3.4%
656	Fever of Unknown Origin	3.4%
657	Flank Pain	3.4%
658	Headache	3.4%
659	Nocturia	3.4%
660	Pain, Intractable	3.4%
661	Pelvic Pain	3.4%
662	Snoring	3.4%
663	Chronic pain	3.4%
664	Lightheadedness	3.4%
665	Pain, Referred	3.4%
666	Prostatism	3.4%
667	Throbbing Headache	3.4%
668	Labor Pain	3.4%
669	Cancer Pain	3.4%
670	Nociceptive Pain	3.4%
671	Vaginal Fistula	3.4%
672	Rectocele	3.4%
673	Brain Neoplasms	3.4%
674	Salivary Gland Neoplasms	3.4%
675	Spinal Cord Neoplasms	3.4%
676	Tongue Neoplasms	3.4%
677	Gastrointestinal Stromal Tumors	3.4%
678	Nasopharyngeal carcinoma	3.4%
679	Primary amyloidosis	3.4%
680	Pituitary Adenoma	3.3%
681	Pituitary Neoplasms	3.3%
682	Body Weight Changes	3.3%
683	Hemangioma, Cavernous	3.3%
684	Leukemia, T-Cell	3.3%
685	Uterine Neoplasms	3.3%
686	Vaginal Neoplasms	3.3%
687	Vulvar Neoplasms	3.3%
688	Uterine Cancer	3.3%
689	Leukemia, B-Cell	3.3%
690	Fallopian Tube Neoplasms	3.3%
691	neurofibroma	3.3%
692	Lymphoma, Follicular	3.3%
693	T-Cell Lymphoma	3.3%
694	Mantle cell lymphoma	3.3%
695	Candidemia	3.2%
696	Bronchial Neoplasms	3.1%
697	Basal Ganglia Hemorrhage	3%
698	Gait Ataxia	3%
699	Multiple Pulmonary Nodules	3%
700	Supratentorial Neoplasms	3%
701	Hoarseness	3%
702	Endometrial Neoplasms	3%
703	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	3%
704	Leukemia, Large Granular Lymphocytic	3%
705	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	3%
706	Lymphoma, T-Cell, Cutaneous	2.9%
707	Lymphoma, AIDS-Related	2.9%
708	Enteropathy-Associated T-Cell Lymphoma	2.9%
709	Primary Effusion Lymphoma	2.9%
710	Sleep Wake Disorders	2.9%
711	Pharyngeal Neoplasms	2.9%
712	ovarian neoplasm	2.9%
713	Dupuytren Contracture	2.9%
714	Pupil Disorders	2.9%
715	Neurobehavioral Manifestations	2.9%
716	Body Weight	2.8%
717	Central Nervous System Cysts	2.8%
718	Urticaria Pigmentosa	2.8%
719	Bile Duct Neoplasms	2.8%
720	Emaciation	2.8%
721	gallbladder neoplasm	2.8%
722	Intestinal Neoplasms	2.8%
723	Low Back Pain	2.8%
724	Penile Neoplasms	2.8%
725	Prostatic Neoplasms	2.8%
726	Stomach Neoplasms	2.8%
727	Visceral Pain	2.8%
728	Brain Stem Neoplasms	2.8%
729	Nasal Polyps	2.8%
730	Mycosis Fungoides	2.8%
731	Lymphomatoid Papulosis	2.8%
732	Plasmablastic lymphoma	2.8%
733	Polycythemia Vera	2.7%
734	Pleural Rub	2.7%
735	Rales	2.7%
736	Respiratory Sounds	2.7%
737	Rhonchi	2.7%
738	Stridor	2.7%
739	Wheezing	2.7%
740	Asterixis	2.7%
741	Ballismus	2.7%
742	Vertigo	2.7%
743	Putaminal Hemorrhage	2.7%
744	Pain	2.7%
745	Xeroderma Pigmentosum	2.7%
746	Livedo Reticularis	2.7%
747	Ache	2.7%
748	Choroid Plexus Papilloma	2.7%
749	Meningocele	2.7%
750	Oliguria	2.7%
751	Polyuria	2.7%
752	Proteinuria	2.7%
753	Urinary Calculi	2.7%
754	Encephalocele	2.7%
755	Underweight	2.6%
756	Overweight	2.6%
757	Akathisia	2.6%
758	Restlessness	2.6%
759	Psychomotor Agitation	2.6%
760	Biliary Fistula	2.6%
761	Gastric Fistula	2.6%
762	Congenital diaphragmatic hernia	2.6%
763	Morning Sickness	2.6%
764	Vesicovaginal Fistula	2.6%
765	Anosmia	2.5%
766	Ataxia	2.5%
767	Athetosis	2.5%
768	Catalepsy	2.5%
769	Dental Fistula	2.5%
770	Dystonia	2.5%
771	Hemiplegia	2.5%
772	Locked-In Syndrome	2.5%
773	Muscle Hypertonia	2.5%
774	Muscle hypotonia	2.5%
775	Myoclonus	2.5%
776	Myotonia	2.5%
777	Neuralgia	2.5%
778	Oroantral Fistula	2.5%
779	Paraplegia	2.5%
780	Pseudobulbar Palsy	2.5%
781	Quadriplegia	2.5%
782	Spasm	2.5%
783	Spastic Paraplegia	2.5%
784	Status Epilepticus	2.5%
785	Taste Disorders	2.5%
786	Tremor	2.5%
787	Monoplegia	2.5%
788	Hypokinesia	2.5%
789	Left Ventricular Hypertrophy	2.5%
790	Gastroparesis	2.5%
791	Right Ventricular Hypertrophy	2.5%
792	Paraparesis	2.5%
793	Bradykinesia	2.5%
794	Waxy flexibility	2.5%
795	Action Tremor	2.5%
796	Resting Tremor	2.5%
797	Dysosmia	2.5%
798	Quadriparesis	2.5%
799	Olfaction Disorders	2.5%
800	Myokymia	2.5%
801	Somatosensory Disorders	2.5%
802	Neuropathic pain	2.5%
803	Hyperkinesia	2.5%
804	Intention tremor	2.5%
805	Cachexia	2.5%
806	Hypopharyngeal Neoplasms	2.5%
807	Pleural Effusion, Malignant	2.5%
808	Hypopharyngeal Cancer	2.5%
809	Waldenstrom Macroglobulinemia	2.5%
810	Multiple Myeloma	2.5%
811	Rectal Prolapse	2.5%
812	Uterine Prolapse	2.5%
813	Vaginal Prolapse	2.5%
814	Laryngeal neoplasm	2.5%
815	Weight Gain	2.5%
816	Parotid Neoplasms	2.5%
817	Prostatic Neoplasms, Castration-Resistant	2.5%
818	Gait Apraxia	2.5%
819	Nelson Syndrome	2.5%
820	Bladder Neoplasm	2.4%
821	Kidney Neoplasm	2.4%
822	Ureteral Neoplasms	2.4%
823	Urethral Neoplasms	2.4%
824	Tonsillar Neoplasms	2.3%
825	Voice Disorders	2.3%
826	Voice Disturbance	2.3%
827	Cerebellar Neoplasms	2.3%
828	Gagging	2.3%
829	Zollinger-Ellison syndrome	2.2%
830	Umbilical hernia	2.1%
831	Toothache	2.1%
832	Cecal Neoplasms	2.1%
833	Duodenal Neoplasms	2.1%
834	Burkitt Lymphoma	2.1%
835	Alexia	2.1%
836	Vision Disorders	2.1%
837	Metamorphopsia	2.1%
838	Dyslexia	2.1%
839	Visual Impairment	2.1%
840	Hyperemesis Gravidarum	2.1%
841	Dysgeusia	2.1%
842	Formication	2.1%
843	Hyperalgesia	2.1%
844	Hyperesthesia	2.1%
845	Hypesthesia	2.1%
846	Language Disorders	2.1%
847	Numbness	2.1%
848	Paresthesia	2.1%
849	Paraparesis, Spastic	2.1%
850	Trismus	2.1%
851	Epilepsia Partialis Continua	2.1%
852	Hypogeusia	2.1%
853	Brown-Sequard Syndrome	2.1%
854	Lockjaw	2.1%
855	Allodynia	2.1%
856	Ageusia	2.1%
857	Bronchial Fistula	2.1%
858	Metatarsalgia	2.1%
859	Pancreatic Fistula	2.1%
860	Alice in Wonderland Syndrome	2%
861	Anisocoria	2%
862	Confusion	2%
863	Facial paralysis	2%
864	Intestinal Fistula	2%
865	Lethargy	2%
866	Memory Disorders	2%
867	Muscle Cramp	2%
868	Perceptual Disorders	2%
869	Psychomotor Disorders	2%
870	Tonic Pupil	2%
871	Anhedonia	2%
872	Disorientation	2%
873	Gastroschisis	2%
874	Enterocutaneous Fistula	2%
875	Fetal Hypoxia	2%
876	Facial Paresis	2%
877	Memory Loss	2%
878	Hemisensory Neglect	2%
879	Dysacusis	2%
880	Dyspnea, Paroxysmal	2%
881	Mastodynia	2%
882	Respiratory Paralysis	2%
883	Salivary Gland Fistula	2%
884	Chorea	2%
885	Cystocele	2%
886	Tetany	2%
887	Urinary Incontinence	2%
888	Breakthrough Pain	2%
889	Sezary Syndrome	2%
890	Radicular Cyst	2%
891	Albuminuria	2%
892	Hemoglobinuria	2%
893	Appendiceal Neoplasms	2%
894	Colonic Neoplasms	2%
895	Rectal Neoplasms	2%
896	Jet Lag Syndrome	1.9%
897	Reflex, Abnormal	1.9%
898	Hyporeflexia	1.9%
899	Hyperreflexia	1.9%
900	Nasopharyngeal Neoplasms	1.9%
901	Birth Weight	1.9%
902	Agraphia	1.9%
903	Anomia	1.9%
904	Cluttering	1.9%
905	Language Development Disorders	1.9%
906	Speech Disorders	1.9%
907	Syncope	1.9%
908	Stupor	1.9%
909	Dysgraphia	1.9%
910	Presyncope	1.9%
911	Dyslalia	1.9%
912	Colorectal Neoplasms	1.8%
913	Aphasia	1.7%
914	Articulation Disorders	1.7%
915	Echolalia	1.7%
916	Stuttering	1.7%
917	Dysphasia	1.7%
918	Consciousness Disorders	1.7%
919	Mental Retardation	1.7%
920	Depressed Level of Consciousness	1.7%
921	Mental deficiency	1.7%
922	Intellectual Disability	1.7%
923	Catatonia	1.7%
924	Musculoskeletal Pain	1.7%
925	Ophthalmoplegia	1.7%
926	External Ophthalmoplegia	1.7%
927	Dysarthria	1.7%
928	Diplopia	1.7%
929	Muscle Rigidity	1.7%
930	Muscle Spasticity	1.7%
931	Scotoma	1.7%
932	Photophobia	1.7%
933	Cogwheel Rigidity	1.7%
934	Hemifacial Spasm	1.7%
935	Amaurosis	1.7%
936	Blindness	1.7%
937	Nuchal Rigidity	1.7%
938	Aphonia	1.7%
939	Arthralgia	1.7%
940	Sleep Deprivation	1.7%
941	Polyarthralgia	1.7%
942	Dysphonia	1.7%
943	Angina Pectoris	1.7%
944	Paranasal Sinus Neoplasms	1.7%
945	Agnosia	1.7%
946	Apraxias	1.7%
947	Hallucinations	1.7%
948	Hemianopsia	1.7%
949	Hyperacusis	1.7%
950	Tinnitus	1.7%
951	Visual Agnosia	1.7%
952	Anosognosia	1.7%
953	Wernicke-Korsakoff Syndrome	1.7%
954	Phonophobia	1.7%
955	Hearing Loss	1.7%
956	Anus Neoplasms	1.7%
957	Sigmoid Neoplasms	1.7%
958	Cerebrospinal Fluid Otorrhea	1.7%
959	Cerebrospinal Fluid Rhinorrhea	1.7%
960	Cerebellar Ataxia	1.7%
961	Torticollis	1.7%
962	Sciatica	1.6%
963	Urge Incontinence	1.6%
964	Tardive Dyskinesia	1.6%
965	Obesity	1.6%
966	Maxillary Sinus Neoplasms	1.5%
967	Amaurosis Fugax	1.5%
968	Blindness, Cortical	1.5%
969	Dyscalculia	1.5%
970	Angina, Unstable	1.5%
971	Hydrops Fetalis	1.5%
972	Deafness	1.5%
973	Hearing Loss, Sudden	1.5%
974	Gerstmann Syndrome	1.5%
975	Hearing Loss, Bilateral	1.5%
976	Hearing Loss, High-Frequency	1.5%
977	Hearing Loss, Mixed Conductive-Sensorineural	1.5%
978	Prosopagnosia	1.5%
979	Apraxia, Ideomotor	1.5%
980	Persistent Vegetative State	1.5%
981	Charles Bonnet Syndrome	1.5%
982	Hearing Loss, Unilateral	1.5%
983	Complete Hearing Loss	1.5%
984	Alien Hand Syndrome	1.5%
985	Deaf Mutism	1.5%
986	Vocal Cord Paralysis	1.5%
987	Fetal Weight	1.5%
988	Urinary Bladder Fistula	1.4%
989	Mutism	1.4%
990	Selective Mutism	1.4%
991	Tinea Pedis	1.4%
992	Amblyopia	1.4%
993	Amnesia	1.4%
994	Delirium	1.4%
995	Horner Syndrome	1.4%
996	Dissociative Amnesia	1.4%
997	Color blindness	1.4%
998	Global Amnesia	1.4%
999	Angina Pectoris, Variant	1.4%
1000	Rectal Fistula	1.4%
1001	Anal Fistula	1.4%
1002	Shoulder Pain	1.4%
1003	Alexia, Pure	1.4%
1004	Pediatric Obesity	1.4%
1005	Dyskinesia, Drug-Induced	1.3%
1006	Alcohol Withdrawal Seizures	1.2%
1007	Arteriovenous fistula	1.2%
1008	Retrograde amnesia	1.2%
1009	Amnesia, Anterograde	1.2%
1010	Akathisia, Drug-Induced	1.2%
1011	Myalgia	1.2%
1012	Kidney Calculi	1.1%
1013	Ureteral Calculi	1.1%
1014	Amnesia, Transient Global	1.1%
1015	Auditory Perceptual Disorders	1%
1016	Ophthalmoplegic Migraine	0.9%
1017	Progressive supranuclear palsy	0.9%
1018	Kearns-Sayre syndrome	0.6%

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