MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Striatonigral Degeneration

(UMLS:C0270733)

Definition:: A sporadic neurodegenerative disease with onset in middle-age characterized clinically by Parkinsonian features (e.g., MUSCLE RIGIDITY; HYPOKINESIA; stooped posture) and HYPOTENSION. This condition is considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Pathologic features include a prominent loss of neurons in the zona compacta of the SUBSTANTIA NIGRA and PUTAMEN. (From Adams et al., Principles of Neurology, 6th ed, p1075-6)
UMLS ID:: C0270733
MeSH ID:: D020955

Classification:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.177.575.550.875|C10.228.140.079.612.800|C10.228.662.550.800|C10.574.625.800

Synonym(s)

Striatonigral Degeneration

SND - Striatonigral degeneration

Striatonigral atrophy

Striatonigral degeneration

degeneration; striatonigral

striatonigral degeneration

striatonigral; degeneration

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Colchicine		18564367	CTD
2	Rotenone		11100151 18155613	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Shy-Drager Syndrome	54.9%
2	Parkinsonian Disorders	37.4%
3	Parkinson Disease	37.1%
4	Lewy Body Disease	36.7%
5	Encephalomyelitis	34.7%
6	Meningoencephalitis	34.2%
7	Dystonia Musculorum Deformans	31.6%
8	Progressive supranuclear palsy	31.5%
9	Prion Diseases	30.9%
10	Meige Syndrome	30.7%
11	Motor Neuron Disease	29.5%
12	Ocular Motility Disorders	29.5%
13	Cyclophoria	29.5%
14	Pneumocephalus	28.4%
15	Subacute Combined Degeneration	28.2%
16	Amyotrophic Lateral Sclerosis	28.1%
17	Huntington Disease	27.6%
18	Stiff-Person Syndrome	26.9%
19	Subdural Effusion	26.6%
20	Asterixis	26.5%
21	Ballismus	26.5%
22	Spinal Muscular Atrophy	26.5%
23	Progressive Muscular Atrophy	26.5%
24	Dandy-Walker Syndrome	26.1%
25	Meningitis	26.1%
26	Pachymeningitis	26.1%
27	Spinal Cord Diseases	26.1%
28	Myelitis	25.6%
29	Basal Ganglia Cerebrovascular Disease	25.5%
30	Epidural Abscess	25.5%
31	Neuroleptic Malignant Syndrome	25.4%
32	Cranial nerve diseases	24.7%
33	Demyelinating Diseases	24.7%
34	Demyelination	24.7%
35	Neuromuscular Diseases	24.7%
36	Chronobiology Disorders	24.7%
37	Autonomic Dysreflexia	23.7%
38	Complex Regional Pain Syndromes	23.7%
39	Brain Abscess	23.5%
40	Essential Tremor	23.1%
41	Familial Tremor	23.1%
42	Writer's Cramp	23.1%
43	MPTP Poisoning	23.1%
44	Marchiafava-Bignami Disease	23%
45	Hepatolenticular Degeneration	22.9%
46	Dementia, Vascular	22.6%
47	Central Nervous System Infection	22.5%
48	Akinetic Mutism	21.8%
49	Anoxic Encephalopathy	21.8%
50	Brain Damage, Chronic	21.8%
51	Cerebellar Diseases	21.8%
52	Encephalitis	21.8%
53	Encephalomalacia	21.8%
54	Epilepsy	21.8%
55	Hydrocephalus	21.8%
56	Congenital Hydrocephalus	21.8%
57	Hypothalamic Diseases	21.8%
58	Thalamic Diseases	21.8%
59	Intracranial Hypertension	21.8%
60	Aura	21.8%
61	Leukoencephalopathy	21.8%
62	Neuroaxonal Dystrophies	21.8%
63	Headache Disorders	21.8%
64	Intracranial Hypotension	21.8%
65	Brain Edema	21.8%
66	Brain Hypoxia	21.8%
67	Aqueductal Stenosis	21.8%
68	Brain Injuries	21.5%
69	Tauopathies	21.5%
70	Brain Neoplasms	21.4%
71	Spinal Cord Injuries	21.4%
72	Restless Legs Syndrome	21.3%
73	Trauma, Nervous System	21.3%
74	Poliomyelitis	21.1%
75	Ophthalmoplegic Migraine	21.1%
76	Myelitis, Transverse	20.8%
77	Epilepsy, Post-Traumatic	20.8%
78	Nervous System Neoplasms	20.8%
79	Neurologic Manifestations	20.8%
80	Neurotoxicity Syndromes	20.8%
81	Limbic Encephalitis	20.8%
82	Akathisia, Drug-Induced	20.7%
83	Polyradiculoneuropathy	20.6%
84	Polyradiculoneuritis	20.6%
85	Multiple System Atrophy	20.4%
86	Cerebral Ventriculitis	19.9%
87	Posterior Leukoencephalopathy Syndrome	19.9%
88	Posterior reversible encephalopathy syndrome	19.9%
89	Myelinolysis, Central Pontine	19.8%
90	Leukoencephalopathy, Progressive Multifocal	19.7%
91	Presenile dementia	19.6%
92	Senile dementia	19.6%
93	Opsoclonus-Myoclonus Syndrome	19.5%
94	Leukoencephalitis, Acute Hemorrhagic	18.9%
95	Chronic Fatigue Syndrome	18.8%
96	Dyskinesia, Drug-Induced	18.7%
97	Lupus Vasculitis, Central Nervous System	18.6%
98	Brain Diseases, Metabolic	18.5%
99	Cerebrovascular Disorders	18.5%
100	Cerebrovascular Insufficiency	18.5%
101	Dementia	18.5%
102	Meningitis, Bacterial	18.2%
103	Meningitis, Fungal	18.2%
104	Brain Death	18.1%
105	Sleep Wake Disorders	18.1%
106	Progressive bulbar palsy	18%
107	Bulbar palsy	18%
108	Lambert-Eaton Myasthenic Syndrome	17.7%
109	Miller Fisher Syndrome	17.6%
110	Leukomalacia, Periventricular	17.5%
111	Cerebellar Neoplasms	17.5%
112	Amblyopia	17.2%
113	Lafora Disease	17.2%
114	Unverricht-Lundborg Syndrome	17.2%
115	Creutzfeldt-Jakob disease	17.2%
116	Brain Diseases	17.2%
117	Vascular Headaches	17.1%
118	Paraneoplastic Cerebellar Degeneration	17.1%
119	Hypoxia-Ischemia, Brain	17.1%
120	Scrapie	16.9%
121	Spinal Cord Neoplasms	16.8%
122	Sweating, Gustatory	16.7%
123	Auriculotemporal Syndrome	16.7%
124	Chorea	16.7%
125	Myoclonic Epilepsy	16.6%
126	Epilepsy, Temporal Lobe	16.6%
127	Epilepsy, Rolandic	16.6%
128	Benign Rolandic Epilepsy	16.6%
129	Orthostatic intolerance	16.6%
130	Basal Ganglia Hemorrhage	16.5%
131	Causalgia	16.5%
132	Encephalomyelitis, Acute Disseminated	16.5%
133	Canavan Disease	16.4%
134	Alexander Disease	16.4%
135	Friedreich Ataxia	16.4%
136	Movement Disorders	16.2%
137	Horner Syndrome	16%
138	Guillain-Barre Syndrome	15.9%
139	Peripheral Nerve Injuries	15.8%
140	Myasthenia Gravis	15.6%
141	Paraneoplastic Encephalomyelitis	15.5%
142	Vasculitis, Central Nervous System	15.4%
143	Arachnoiditis	15.3%
144	Aseptic Meningitis	15.3%
145	Syringomyelia	15.3%
146	Pneumorrhachis	15.3%
147	Brain Hemorrhage, Traumatic	14.9%
148	Torticollis	14.7%
149	Reflex Sympathetic Dystrophy	14.6%
150	Amnesia, Transient Global	14.4%
151	Toxoplasmosis, Cerebral	14.3%
152	Carotid Artery Injuries	14.1%
153	Sleep Disorders, Circadian Rhythm	14%
154	Cerebral Palsy	13.9%
155	Epilepsies, Partial	13.9%
156	Epilepsy, Generalized	13.9%
157	Pseudotumor Cerebri	13.9%
158	Hypertensive Encephalopathy	13.9%
159	Simple Partial Seizures	13.9%
160	Epilepsy, Reflex	13.9%
161	Headache Disorders, Primary	13.9%
162	Headache Disorders, Secondary	13.9%
163	Medication overuse headache	13.9%
164	Brain Injuries, Diffuse	13.9%
165	Traumatic Brain Injury	13.9%
166	Cerebellar Ataxia	13.8%
167	Supratentorial Neoplasms	13.8%
168	Tuberculosis, Meningeal	13.7%
169	Neuromyelitis Optica	13.7%
170	Olfactory Nerve Injuries	13.6%
171	Botulism	13.6%
172	Central Nervous System Cysts	13.6%
173	Vagus Nerve Disorder	13.5%
174	Glossopharyngeal Neuralgia	13.5%
175	Abducens Nerve Diseases	13.5%
176	Heavy Metal Poisoning, Nervous System	13.5%
177	Neuromuscular Junction Diseases	13.5%
178	Trochlear Nerve Diseases	13.5%
179	Peripheral Nervous System Diseases	13.5%
180	Putaminal Hemorrhage	13.4%
181	Juvenile Myoclonic Epilepsy	13.4%
182	Myoclonic Epilepsies, Progressive	13.4%
183	Striatonigral Degeneration	13.4%
184	Pituitary Adenoma	13.3%
185	Pituitary Neoplasms	13.3%
186	Postural Orthostatic Tachycardia Syndrome	13.3%
187	Central Cord Syndrome	13.2%
188	Central Nervous System Fungal Infections	12.9%
189	Conus Medullaris Syndrome	12.9%
190	Spinal Cord Vascular Diseases	12.9%
191	Persistent Vegetative State	12.9%
192	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	12.8%
193	Tuberous Sclerosis	12.8%
194	Pituitary Apoplexy	12.6%
195	Brain Infarction	12.5%
196	Facial Nerve Injuries	12.2%
197	Frontotemporal dementia	12.1%
198	Charcot-Marie-Tooth Disease	12.1%
199	Pituitary Diseases	12%
200	Tardive Dyskinesia	12%
201	Myotonia Congenita	11.9%
202	Myopathy	11.7%
203	Optic Neuropathy	11.7%
204	Multiple Sclerosis	11.7%
205	Carotid Artery Diseases	11.7%
206	Brain Ischemia	11.7%
207	Cerebrovascular accident	11.7%
208	Kluver-Bucy Syndrome	11.7%
209	Vasospasm, Intracranial	11.7%
210	Intracranial Arterial Diseases	11.7%
211	Ataxia Telangiectasia	11.6%
212	Facial Nerve Diseases	11.4%
213	Craniocerebral Trauma	11.4%
214	Parasomnia	11.4%
215	Dyssomnias	11.4%
216	Nocturnal Myoclonus Syndrome	11.4%
217	Vestibulocochlear Nerve Diseases	11.3%
218	Decerebrate State	11.3%
219	Hemiparesis	11.3%
220	Hydranencephaly	11.3%
221	Meningism	11.3%
222	Neural Tube Defects	11.3%
223	Paresis	11.3%
224	Seizures	11.3%
225	Sensation Disorders	11.3%
226	Tethered Cord Syndrome	11.3%
227	Central Nervous System Neoplasms	11.3%
228	Complex partial seizures	11.3%
229	Iniencephaly	11.3%
230	Craniorachischisis	11.3%
231	Exencephaly	11.3%
232	Monoparesis	11.3%
233	Septo-Optic Dysplasia	11.3%
234	Cortical Dysplasia	11.3%
235	Neurogenic Inflammation	11.3%
236	Gait Disorders, Neurologic	11.3%
237	Neuromuscular Manifestations	11.3%
238	Malformations of Cortical Development	11.3%
239	Central Nervous System Bacterial Infections	11.2%
240	Hypotension, Orthostatic	11.1%
241	Post-Exercise Hypotension	11.1%
242	Infarction, Middle Cerebral Artery	11%
243	Infarction, Anterior Cerebral Artery	11%
244	Infarction, Posterior Cerebral Artery	11%
245	Meningitis, Cryptococcal	10.9%
246	Myasthenia Gravis, Autoimmune, Experimental	10.9%
247	Meningitis, Listeria	10.9%
248	Meningitis, Haemophilus	10.9%
249	Meningitis, Pneumococcal	10.9%
250	Mitochondrial Encephalomyopathies	10.8%
251	Jet Lag Syndrome	10.6%
252	Subacute Sclerosing Panencephalitis	10.6%
253	Refsum Disease	10.5%
254	Myotonic Dystrophy	10.5%
255	Basal Ganglia Diseases	10.4%
256	Ophthalmoplegia	10.3%
257	External Ophthalmoplegia	10.3%
258	Dysautonomia	10.2%
259	Vertebral Artery Dissection	10.1%
260	Diffuse Axonal Injury	10.1%
261	Brain Stem Neoplasms	10.1%
262	Adrenoleukodystrophy	10.1%
263	Moyamoya Disease	10%
264	Reye Syndrome	10%
265	Cerebral Infarction	10%
266	Post-Traumatic Headache	10%
267	Tension Headache	10%
268	Epilepsy, Complex Partial	10%
269	Migraine Disorders	10%
270	Abdominal Migraine	10%
271	Status Migrainosus	10%
272	Cervicogenic Headache	10%
273	Brain Stem Infarctions	10%
274	Intracranial Embolism and Thrombosis	10%
275	Hepatic Encephalopathy	10%
276	Pupil Disorders	10%
277	Neurobehavioral Manifestations	10%
278	Brain Concussion	9.8%
279	Subarachnoid Hemorrhage, Traumatic	9.8%
280	Carotid Artery, Internal, Dissection	9.8%
281	Auditory Perceptual Disorders	9.7%
282	Acrodynia	9.7%
283	Uveomeningoencephalitic Syndrome	9.7%
284	Sturge-Weber Syndrome	9.6%
285	Vertigo	9.6%
286	Alcohol-Induced Disorders, Nervous System	9.6%
287	Alice in Wonderland Syndrome	9.5%
288	MELAS Syndrome	9.3%
289	Vocal Cord Paralysis	9.2%
290	Brachial Plexus Neuritis	9.2%
291	Neuralgic Amyotrophy	9.2%
292	Brain Contusion	8.9%
293	Brain Diseases, Metabolic, Inborn	8.8%
294	Lateral Medullary Syndrome	8.8%
295	Voice Disorders	8.6%
296	Voice Disturbance	8.6%
297	Amyloid Neuropathies, Familial	8.5%
298	Cerebrospinal Fluid Otorrhea	8.5%
299	Cerebrospinal Fluid Rhinorrhea	8.5%
300	Neuritis, Autoimmune, Experimental	8.5%
301	Gait Ataxia	8.5%
302	Smith-Magenis syndrome	8.5%
303	Empty Sella Syndrome	8.5%
304	Hyperpituitarism	8.5%
305	Hypopituitarism	8.5%
306	Hypophysitis	8.5%
307	Dural Arteriovenous Fistula	8.5%
308	Spinal Cord Ischemia	8.4%
309	Alstrom Syndrome	8.4%
310	Coma, Post-Head Injury	8.4%
311	Cerebral Arterial Diseases	8.3%
312	Vertebrobasilar Insufficiency	8.3%
313	Basilar Artery Stenosis	8.3%
314	Vertebral Artery Stenosis	8.3%
315	Intracranial Hemorrhage, Hypertensive	8.3%
316	Transient Cerebral Ischemia	8.3%
317	Tuberculosis, Central Nervous System	8.3%
318	Giant Cell Arteritis	8.3%
319	Temporal Arteritis	8.3%
320	Choroid Plexus Papilloma	8.2%
321	Neuritis	8.1%
322	Polyneuritis	8.1%
323	Radiculitis	8.1%
324	Polyneuropathy	8.1%
325	Mononeuritis	8.1%
326	Mononeuropathies	8.1%
327	Alcohol Withdrawal Seizures	8.1%
328	Brachial Plexus Neuropathies	8.1%
329	Radiculopathy	8.1%
330	Mononeuropathy Multiplex	8.1%
331	Nerve Root Compression	8.1%
332	West Nile Fever	8.1%
333	Tarsal Tunnel Syndrome	8.1%
334	Cauda Equina Syndrome	8.1%
335	Cluster Headache	8.1%
336	Migraine with Aura	8.1%
337	Familial Hemiplegic Migraine	8.1%
338	Chronic Paroxysmal Hemicrania	8.1%
339	SUNCT Syndrome	8.1%
340	Paroxysmal Hemicrania	8.1%
341	Multiple Sclerosis, Chronic Progressive	7.8%
342	Multiple Sclerosis, Relapsing-Remitting	7.8%
343	Wernicke Encephalopathy	7.8%
344	AIDS Dementia Complex	7.8%
345	Akathisia	7.6%
346	Restlessness	7.6%
347	Psychomotor Agitation	7.6%
348	Reflex, Abnormal	7.5%
349	Hyporeflexia	7.5%
350	Hyperreflexia	7.5%
351	Neuronal Ceroid-Lipofuscinoses	7.4%
352	Optic Nerve Glioma	7.3%
353	Neuroaspergillosis	7.2%
354	Carotid Stenosis	7.2%
355	Intracranial Aneurysm	7.2%
356	Intracranial Arteriosclerosis	7.1%
357	Cerebral Atherosclerosis	7.1%
358	Subarachnoid Hemorrhage	7.1%
359	Cerebral Arteriosclerosis	7.1%
360	Cerebral Hemorrhage	7.1%
361	Cerebral Thrombosis	7.1%
362	Intracranial Embolism	7.1%
363	Intracranial Thrombosis	7.1%
364	Kernicterus	7.1%
365	Carpal Tunnel Syndrome	6.9%
366	neurofibroma	6.9%
367	Sciatica	6.9%
368	Myositis	6.9%
369	Optic Atrophy	6.9%
370	Optic Neuritis	6.9%
371	Papilledema	6.9%
372	Strabismus	6.9%
373	Tolosa-Hunt Syndrome	6.9%
374	Isaacs syndrome	6.9%
375	Arsenic Poisoning	6.9%
376	Myotonic Disorders	6.9%
377	Myasthenic Syndromes, Congenital	6.9%
378	Gait Apraxia	6.8%
379	Diabetic Neuropathies	6.8%
380	Facial Injuries	6.8%
381	Facial Neuralgia	6.8%
382	Diabetic Amyotrophy	6.8%
383	Diabetic Autonomic Neuropathy	6.8%
384	Sleep Talking	6.8%
385	Manganese Poisoning	6.8%
386	Sleep Disorders, Intrinsic	6.8%
387	Anosmia	6.8%
388	Ataxia	6.8%
389	Athetosis	6.8%
390	Catalepsy	6.8%
391	Dystonia	6.8%
392	Hemiplegia	6.8%
393	Locked-In Syndrome	6.8%
394	Meningeal Neoplasms	6.8%
395	Meningomyelocele	6.8%
396	Muscle Hypertonia	6.8%
397	Muscle hypotonia	6.8%
398	Myoclonus	6.8%
399	Myotonia	6.8%
400	Neuralgia	6.8%
401	Paraplegia	6.8%
402	Pseudobulbar Palsy	6.8%
403	Quadriplegia	6.8%
404	Spasm	6.8%
405	Spastic Paraplegia	6.8%
406	Status Epilepticus	6.8%
407	Taste Disorders	6.8%
408	Tremor	6.8%
409	Spina Bifida	6.8%
410	Monoplegia	6.8%
411	Hypokinesia	6.8%
412	Paraparesis	6.8%
413	Bradykinesia	6.8%
414	Waxy flexibility	6.8%
415	Action Tremor	6.8%
416	Resting Tremor	6.8%
417	Dysosmia	6.8%
418	Quadriparesis	6.8%
419	Mercury Poisoning, Nervous System	6.8%
420	Olfaction Disorders	6.8%
421	Myokymia	6.8%
422	Lead Poisoning, Nervous System	6.8%
423	Vestibular Neuronitis	6.8%
424	Somatosensory Disorders	6.8%
425	Neuropathic pain	6.8%
426	Hyperkinesia	6.8%
427	Intention tremor	6.8%
428	Hematoma, Subdural	6.8%
429	Hematoma, Epidural, Cranial	6.8%
430	Hyperprolactinemia	6.7%
431	Cockayne Syndrome	6.7%
432	Subclavian Steal Syndrome	6.7%
433	Pick Disease of the Brain	6.7%
434	Pseudorabies	6.6%
435	Neurosyphilis	6.3%
436	Acoustic Neuroma	6.2%
437	Carotid Artery Thrombosis	6.2%
438	Optic Atrophy, Hereditary, Leber	6.2%
439	Anterior Spinal Artery Syndrome	6.2%
440	Hand-Arm Vibration Syndrome	6.1%
441	Vision Disorders	6%
442	Metamorphopsia	6%
443	Visual Impairment	6%
444	Cubital Tunnel Syndrome	6%
445	Fibromyalgia	6%
446	Optic Neuropathy, Ischemic	6%
447	Anterior Ischemic Optic Neuropathy	6%
448	Medial Tibial Stress Syndrome	6%
449	Facial Hemiatrophy	5.9%
450	Melkersson-Rosenthal Syndrome	5.9%
451	Mitochondrial Myopathies	5.9%
452	Anisocoria	5.9%
453	Confusion	5.9%
454	Facial paralysis	5.9%
455	Lethargy	5.9%
456	Memory Disorders	5.9%
457	Muscle Cramp	5.9%
458	Perceptual Disorders	5.9%
459	Psychomotor Disorders	5.9%
460	Tonic Pupil	5.9%
461	Eosinophilia-Myalgia Syndrome	5.9%
462	Anhedonia	5.9%
463	Disorientation	5.9%
464	Facial Paresis	5.9%
465	Memory Loss	5.9%
466	Hemisensory Neglect	5.9%
467	Dysacusis	5.9%
468	Sleep Bruxism	5.9%
469	Anencephaly	5.8%
470	Meningocele	5.8%
471	Muscular Atrophy	5.8%
472	Respiratory Paralysis	5.8%
473	Encephalocele	5.8%
474	Acromegaly	5.8%
475	Tetany	5.8%
476	Cerebral Amyloid Angiopathy	5.7%
477	Sinus Thrombosis, Intracranial	5.7%
478	Hematoma, Subdural, Intracranial	5.6%
479	Hematoma, Subdural, Chronic	5.6%
480	Hematoma, Subdural, Acute	5.6%
481	Lyme Neuroborreliosis	5.6%
482	Sciatic Neuropathy	5.5%
483	Ulnar Neuropathies	5.5%
484	Lesion of Sciatic Nerve	5.5%
485	Ulnar Neuritis	5.5%
486	Radial nerve compression	5.5%
487	Radial Tunnel Syndrome	5.5%
488	Peroneal Neuropathies	5.5%
489	Radial Neuropathy	5.5%
490	Median Neuropathy	5.5%
491	Sciatic Nerve Palsy	5.5%
492	Femoral Neuropathy	5.5%
493	Tibial Neuropathy	5.5%
494	Ulnar Nerve Palsy	5.5%
495	Radial nerve palsy	5.5%
496	Toxoplasmosis, Congenital	5.4%
497	Classical Lissencephalies and Subcortical Band Heterotopias	5.4%
498	Malaria, Cerebral	5.3%
499	Neurocysticercosis	5.3%
500	Fabry Disease	5.3%
501	Duane Retraction Syndrome	5.2%
502	Waterhouse-Friderichsen Syndrome	5.2%
503	Consciousness Disorders	5.2%
504	Mental Retardation	5.2%
505	Muscle Weakness	5.2%
506	Depressed Level of Consciousness	5.2%
507	Mental deficiency	5.2%
508	Intellectual Disability	5.2%
509	Mobius Syndrome	5.2%
510	Bell Palsy	5.2%
511	Catatonia	5.2%
512	Herpes Zoster Oticus	5.1%
513	Familial Periodic Paralysis	5.1%
514	Aphonia	5.1%
515	Sleep Deprivation	5.1%
516	Dysphonia	5.1%
517	Menkes Kinky Hair Syndrome	5.1%
518	Cavernous Sinus Thrombosis	5%
519	Sagittal Sinus Thrombosis	5%
520	Galactosemias	5%
521	Urea Cycle Disorders, Inborn	5%
522	Tyrosinemias	5%
523	Thoracic Outlet Syndrome	4.7%
524	Alexia	4.6%
525	Dyslexia	4.6%
526	Esotropia	4.6%
527	Exotropia	4.6%
528	Sleep Apnea Syndromes	4.6%
529	Polymyositis	4.6%
530	Disorders of Excessive Somnolence	4.6%
531	Sleep Initiation and Maintenance Disorders	4.6%
532	Night Terrors	4.6%
533	Somnambulism	4.6%
534	Trigeminal Nerve Disorder	4.6%
535	Transient Insomnia	4.6%
536	Sleep Paralysis	4.6%
537	Chronic Insomnia	4.6%
538	REM Sleep Behavior Disorder	4.6%
539	Hypersomnia	4.6%
540	Homocystinuria	4.6%
541	Dermal Sinus	4.6%
542	Dysgeusia	4.6%
543	Formication	4.6%
544	Hyperalgesia	4.6%
545	Hyperesthesia	4.6%
546	Hypesthesia	4.6%
547	Language Disorders	4.6%
548	Numbness	4.6%
549	Paresthesia	4.6%
550	Paraparesis, Spastic	4.6%
551	Spina Bifida Cystica	4.6%
552	Trismus	4.6%
553	Spina Bifida Occulta	4.6%
554	Epilepsia Partialis Continua	4.6%
555	Hypogeusia	4.6%
556	Meningeal Carcinomatosis	4.6%
557	Brown-Sequard Syndrome	4.6%
558	Lissencephaly	4.6%
559	Polymicrogyria	4.6%
560	Pachygyria	4.6%
561	Schizencephaly	4.6%
562	Lockjaw	4.6%
563	Allodynia	4.6%
564	Lead Poisoning, Nervous System, Childhood	4.6%
565	Lead Poisoning, Nervous System, Adult	4.6%
566	Periventricular Nodular Heterotopia	4.6%
567	Ageusia	4.6%
568	Leigh Disease	4.5%
569	Myalgia	4.5%
570	Prolactinoma	4.5%
571	Growth Hormone-Secreting Pituitary Adenoma	4.5%
572	Kearns-Sayre syndrome	4.5%
573	Nelson Syndrome	4.4%
574	Neurofibrosarcoma	4.3%
575	Polyradiculopathy	4.2%
576	Aicardi's syndrome	4.2%
577	Hoarseness	4.1%
578	Alcohol Withdrawal Delirium	4.1%
579	Eye Injuries	4.1%
580	Muscular Dystrophy	4%
581	Congenital nystagmus	4%
582	Orbital Myositis	4%
583	Diplopia	4%
584	Muscle Rigidity	4%
585	Muscle Spasticity	4%
586	Scotoma	4%
587	Photophobia	4%
588	Cogwheel Rigidity	4%
589	Hemifacial Spasm	4%
590	Amaurosis	4%
591	Blindness	4%
592	Nuchal Rigidity	4%
593	Pyomyositis	4%
594	Agnosia	3.9%
595	Apraxias	3.9%
596	Hallucinations	3.9%
597	Hemianopsia	3.9%
598	Hyperacusis	3.9%
599	Tinnitus	3.9%
600	Visual Agnosia	3.9%
601	Anosognosia	3.9%
602	Wernicke-Korsakoff Syndrome	3.9%
603	Phonophobia	3.9%
604	Hearing Loss	3.9%
605	Sarcopenia	3.9%
606	Holoprosencephaly	3.7%
607	Carbamoyl-Phosphate Synthase I Deficiency Disease	3.6%
608	Zellweger Syndrome	3.6%
609	Sleep Apnea, Obstructive	3.5%
610	Sleep Apnea, Central	3.5%
611	Narcolepsy	3.5%
612	Trigeminal Neuralgia	3.5%
613	Kleine-Levin Syndrome	3.5%
614	Amnesia	3.5%
615	Delirium	3.5%
616	Dissociative Amnesia	3.5%
617	Color blindness	3.5%
618	Global Amnesia	3.5%
619	Agraphia	3.5%
620	Anomia	3.5%
621	Cluttering	3.5%
622	Language Development Disorders	3.5%
623	Speech Disorders	3.5%
624	Syncope	3.5%
625	Stupor	3.5%
626	Dysgraphia	3.5%
627	Presyncope	3.5%
628	Dyslalia	3.5%
629	Cri-du-Chat Syndrome	3.5%
630	Down Syndrome	3.5%
631	Trisomy 21	3.5%
632	POEMS Syndrome	3.5%
633	Meningioma	3.5%
634	Williams Syndrome	3.5%
635	Microcephaly	3.4%
636	Macrocephaly	3.4%
637	Hypokalemic periodic paralysis	3.4%
638	Porencephaly	3.4%
639	Glycogen storage disease type II	3.3%
640	Prader-Willi Syndrome	3.1%
641	Phantom pain	3.1%
642	Phantom Limb Pain	3.1%
643	Eye Burns	3%
644	Welander Distal Myopathy	3%
645	Amaurosis Fugax	3%
646	Blindness, Cortical	3%
647	Dyscalculia	3%
648	Rett Syndrome	3%
649	Deafness	3%
650	Hearing Loss, Sudden	3%
651	Gerstmann Syndrome	3%
652	Hearing Loss, Bilateral	3%
653	Hearing Loss, High-Frequency	3%
654	Hearing Loss, Mixed Conductive-Sensorineural	3%
655	Prosopagnosia	3%
656	Apraxia, Ideomotor	3%
657	Charles Bonnet Syndrome	3%
658	Hearing Loss, Unilateral	3%
659	Complete Hearing Loss	3%
660	Alien Hand Syndrome	3%
661	Deaf Mutism	3%
662	Cataplexy	2.9%
663	Aphasia	2.9%
664	Articulation Disorders	2.9%
665	Echolalia	2.9%
666	Stuttering	2.9%
667	Dysphasia	2.9%
668	Gaucher Disease	2.7%
669	Dermatomyositis	2.7%
670	Corneal Scar	2.7%
671	Dysarthria	2.7%
672	Muscular Dystrophy, Duchenne	2.6%
673	Retrograde amnesia	2.6%
674	Amnesia, Anterograde	2.6%
675	Mutism	2.6%
676	Selective Mutism	2.6%
677	Rubinstein-Taybi Syndrome	2.5%
678	Tay-Sachs Disease	2.4%
679	Fragile X Syndrome	2.3%
680	Niemann-Pick Disease, Type C	2.3%
681	Alexia, Pure	2.3%
682	Corneal Perforation	2.2%
683	Mucopolysaccharidosis II	1.7%

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