MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Leukoplakia, Oral

(UMLS:C0023532)

Definition:: A white patch seen on the oral mucosa. It is considered a premalignant condition and is often tobacco-induced. When evidence of Epstein-Barr virus is present, the condition is called hairy leukoplakia (LEUKOPLAKIA, HAIRY).
UMLS ID:: C0023532
MeSH ID:: D007972

Classification 1:

Name:

Neoplasms
MeSH Tree Number(s):: C04.588.443.591.545|C04.834.512.513

Classification 2:

Name:

Stomatognathic Diseases
MeSH Tree Number(s):: C07.465.530.545

Classification 3:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.300.816.513

Synonym(s)

Leukoplakia, Oral

LEUKOPLAKIA OF MOUTH

LEUKOPLAKIA ORAL

Leucoplakia of oral mucosa

Leukokeratosis of Oral Mucosa

Leukokeratosis of oral mucosa

Leukoplakia of Mouth

Leukoplakia of Oral Mucosa

Leukoplakia of oral mucosa

10.

Leukoplakia of oral mucosa, NOS

11.

Leukoplakia of the Mouth

12.

Leukoplakia of the Oral Mucosa

13.

Leukoplakia oral

14.

Leukoplakia;oral

15.

Mouth Leukoplakia

16.

ORAL LEUKOPLAKIA

17.

Oral Cavity Leukoplakia

18.

Oral Keratoses

19.

Oral Keratosis

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Celecoxib		18202791	CTD
2	Fenretinide		16707609	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Salivary Gland Neoplasms	34.4%
2	Tongue Neoplasms	34.4%
3	Parotid Neoplasms	26.1%
4	Palatal Neoplasms	23.6%
5	Cyst	21.4%
6	Oral Fistula	16.8%
7	Parathyroid Neoplasms	16%
8	Thyroid Neoplasm	16%
9	Thyroid carcinoma	16%
10	Salivary Gland Fistula	15.6%
11	Erythroplasia	15.4%
12	Aberrant Crypt Foci	15.4%
13	Neoplastic Processes	14.5%
14	Facial Hemiatrophy	14.4%
15	Melkersson-Rosenthal Syndrome	14.4%
16	Tracheal Neoplasms	14.3%
17	Abdominal Neoplasms	14.1%
18	Soft Tissue Neoplasms	14.1%
19	Thoracic Neoplasms	14.1%
20	Granulomatosis, Orofacial	13.6%
21	Multiple Endocrine Neoplasia	13.2%
22	Hamartoma	13.1%
23	Neoplasms, Hormone-Dependent	13.1%
24	Neoplasms, Multiple Primary	13.1%
25	Paraneoplastic Syndromes	13.1%
26	Neoplasms, Second Primary	13.1%
27	Barrett Esophagus	12.8%
28	Actinic keratosis	12.8%
29	Parovarian Cyst	12.8%
30	Bell Palsy	12.6%
31	Esophageal Neoplasms	12.5%
32	Digestive System Neoplasms	12.1%
33	Endocrine Gland Neoplasms	12.1%
34	Eye Neoplasms	12.1%
35	Nervous System Neoplasms	12.1%
36	Burning Mouth Syndrome	12.1%
37	Calculi	12.1%
38	Hernia	12.1%
39	Hypertrophy	12.1%
40	Lip Diseases	12.1%
41	Microglossia	12.1%
42	Nails, Malformed	12.1%
43	Oral Submucous Fibrosis	12.1%
44	Periodontal Diseases	12.1%
45	polyps	12.1%
46	Rupture, Spontaneous	12.1%
47	Salivary Gland Diseases	12.1%
48	Stomatitis	12.1%
49	Tongue Diseases	12.1%
50	Oral Ulcer	12.1%
51	Enterocele	12.1%
52	Atheroma	12.1%
53	Stenosis	12.1%
54	Facial asymmetry	12.1%
55	Plaque, Amyloid	12.1%
56	Plaque, Atherosclerotic	12.1%
57	Bone neoplasms	11.9%
58	Skin Neoplasms	11.9%
59	Hematologic Neoplasms	11.9%
60	Splenic Neoplasms	11.7%
61	Vascular Remodeling	11.7%
62	Mouth Abnormalities	11.6%
63	Paraneoplastic Encephalomyelitis	11.6%
64	Dental Fistula	11.5%
65	Oroantral Fistula	11.5%
66	Mammary Neoplasms, Experimental	11.4%
67	Gingival Hemorrhage	11.3%
68	Lymphomatoid Granulomatosis	11.1%
69	Neoplastic Syndromes, Hereditary	11%
70	Pregnancy Complications, Neoplastic	11%
71	Peritoneal Neoplasms	11%
72	Neoplasms, Experimental	10.9%
73	Thyroid Nodule	10.7%
74	Facial Nerve Diseases	10.2%
75	Airway Remodeling	10.2%
76	Oral candidiasis	10.1%
77	Tooth Loss	10.1%
78	Ventricular Remodeling	10.1%
79	Alopecia	10%
80	Facial paralysis	10%
81	Androgenetic Alopecia	10%
82	Facial Paresis	10%
83	Lichen Planus, Oral	10%
84	Acanthoma	9.9%
85	Gingival Recession	9.8%
86	Parotitis	9.8%
87	Gingival Atrophy	9.8%
88	Pancreatic Neoplasm	9.8%
89	Pharyngeal Neoplasms	9.7%
90	Hemifacial Spasm	9.7%
91	Carcinoma 256, Walker	9.5%
92	Neoplasms, Radiation-Induced	9.3%
93	Carcinoma, Lobular	9%
94	Carcinoma, Ehrlich Tumor	8.9%
95	Dermoid Cyst	8.9%
96	Carcinoma, Lewis Lung	8.9%
97	Incisional hernia	8.8%
98	Meningioma	8.6%
99	Trophoblastic Neoplasms	8.6%
100	Retroperitoneal Neoplasms	8.6%
101	Leukemia, Experimental	8.6%
102	Tuberous Sclerosis	8.6%
103	Diverticulum	8.5%
104	Diverticulosis	8.5%
105	Multiple Endocrine Neoplasia Type 1	8.4%
106	Neoplasm Invasiveness	8.4%
107	Neoplasm Metastasis	8.4%
108	Neoplasm Recurrence, Local	8.4%
109	Carcinogenesis	8.4%
110	Metastasis	8.4%
111	Melanoma, Experimental	8.4%
112	Ear Neoplasms	8.2%
113	Eyelid Neoplasms	8.2%
114	Giant Cell Epulis	8%
115	Neoplasms, Neuroepithelial	8%
116	Gliomatosis cerebri	8%
117	Nose Neoplasms	8%
118	Cheilitis	7.9%
119	Drooling	7.9%
120	Gingival Diseases	7.9%
121	Glossitis	7.9%
122	Diaphragmatic Hernia	7.9%
123	Intestinal Polyps	7.9%
124	Macroglossia	7.9%
125	Periodontitis	7.9%
126	Sialadenitis	7.9%
127	Sialometaplasia, Necrotizing	7.9%
128	Sialorrhea	7.9%
129	Splenomegaly	7.9%
130	Aphthous Stomatitis	7.9%
131	Xerostomia	7.9%
132	Glossoptosis	7.9%
133	Peri-Implantitis	7.9%
134	Neuroectodermal Tumors	7.7%
135	Carcinoma, Pancreatic Ductal	7.6%
136	Sarcoma, Experimental	7.6%
137	Leukemia, Radiation-Induced	7.6%
138	Macrostomia	7.5%
139	Microstomia	7.5%
140	Thymoma	7.5%
141	Follicular cyst	7.4%
142	leukemia	7.4%
143	Mucocele	7.4%
144	Neoplasms, Germ Cell and Embryonal	7.4%
145	Neoplasms, Glandular and Epithelial	7.4%
146	Pilonidal Cyst	7.4%
147	Thyroglossal Cyst	7.4%
148	Synovial Cyst	7.4%
149	Germ Cell Cancer	7.4%
150	Liver Neoplasms, Experimental	7.4%
151	Testicular Neoplasms	7.3%
152	Central Nervous System Neoplasms	7.3%
153	Vascular Neoplasms	7.3%
154	Thymus Neoplasms	7.3%
155	Genital Neoplasms, Female	7.2%
156	Breast Neoplasms, Male	7.1%
157	Triple Negative Breast Neoplasms	7.1%
158	Muscular Atrophy	7.1%
159	Medulloblastoma	7.1%
160	Hypopharyngeal Neoplasms	7%
161	Hypopharyngeal Cancer	7%
162	melanoma	7%
163	Nasopharyngeal Neoplasms	6.9%
164	Signs and Symptoms	6.9%
165	Tooth Diseases	6.9%
166	Radicular Cyst	6.9%
167	Respiratory Tract Fistula	6.9%
168	Nephroblastoma	6.8%
169	Polydipsia	6.8%
170	Cardiomegaly	6.7%
171	Hepatomegaly	6.7%
172	Spermatocele	6.7%
173	Cutaneous Fistula	6.7%
174	Cardiac Hypertrophy	6.7%
175	Acoustic Neuroma	6.7%
176	Facial Neuralgia	6.6%
177	Carcinosarcoma	6.6%
178	Hemangiosarcoma	6.6%
179	Leukemia L1210	6.6%
180	Leukemia P388	6.6%
181	lymphangiosarcoma	6.6%
182	Vaginal Fistula	6.6%
183	Rectocele	6.6%
184	Retinoblastoma	6.6%
185	Paraneoplastic Cerebellar Degeneration	6.6%
186	Basal Cell Nevus Syndrome	6.6%
187	Choriocarcinoma	6.5%
188	Nasopharyngeal carcinoma	6.5%
189	Laryngeal neoplasm	6.4%
190	Xeroderma Pigmentosum	6.4%
191	Adrenal Gland Neoplasms	6.3%
192	Gastrointestinal Neoplasms	6.3%
193	Genital Neoplasms, Male	6.3%
194	Liver neoplasms	6.3%
195	Uveal Neoplasms	6.3%
196	Urologic Neoplasms	6.2%
197	Lymphocele	6.2%
198	Pancreatic Cyst	6.2%
199	Precancerous Conditions	6.2%
200	Vipoma	6.2%
201	Sebaceous Gland Neoplasms	6.2%
202	Spinal Neoplasms	6.2%
203	Bone Marrow Neoplasms	6.2%
204	Breast Cyst	6.1%
205	Histiocytic Disorders, Malignant	6.1%
206	Mediastinal Cyst	6.1%
207	Pericardial Cyst	6.1%
208	Thymic Cyst	6.1%
209	Myxoid cyst	6.1%
210	Adenoma, Acidophil	6%
211	Ganglioneuroma	6%
212	Glioma	6%
213	Malignant Glioma	6%
214	Sarcoma 180	6%
215	Behcet Syndrome	6%
216	Vesicovaginal Fistula	5.9%
217	Colonic Polyps	5.9%
218	Gingivitis	5.9%
219	Glossitis, Benign Migratory	5.9%
220	Pericoronitis	5.9%
221	Aggressive Periodontitis	5.9%
222	Gingival Overgrowth	5.9%
223	Jaw Diseases	5.9%
224	Pharyngeal Diseases	5.9%
225	Limbic Encephalitis	5.8%
226	insulinoma	5.8%
227	Vesicular Stomatitis	5.8%
228	Nasal Polyps	5.8%
229	Cleft Palate	5.8%
230	Hepatocellular Adenoma	5.8%
231	Composite Lymphoma	5.8%
232	Tonsillar Neoplasms	5.7%
233	Gastrinoma	5.7%
234	Glucagonoma	5.7%
235	Meningocele	5.7%
236	Urinary Calculi	5.7%
237	Encephalocele	5.7%
238	Leukemia, Plasma Cell	5.6%
239	Carcinoid Tumor	5.6%
240	Neurilemmoma	5.6%
241	Hutchinson's Melanotic Freckle	5.6%
242	Melanoma, Amelanotic	5.6%
243	Optic Nerve Glioma	5.5%
244	Lymphatic Metastasis	5.5%
245	Neoplasms, Unknown Primary	5.5%
246	Leukemic Infiltration	5.5%
247	Neoplasm Micrometastasis	5.5%
248	Basal cell carcinoma	5.5%
249	Carcinoma, Papillary	5.5%
250	Squamous cell carcinoma	5.5%
251	Chondrosarcoma	5.5%
252	Craniopharyngioma	5.5%
253	Cystadenoma	5.5%
254	leiomyosarcoma	5.5%
255	liposarcoma	5.5%
256	Mesothelioma	5.5%
257	synovial sarcoma	5.5%
258	Neuroectodermal Tumor, Melanotic	5.5%
259	Angiomyolipoma	5.5%
260	Clear Cell Sarcoma of Soft Tissue	5.5%
261	Alveolar Soft Part Sarcoma	5.5%
262	Neuroendocrine Tumors	5.5%
263	Sarcoma, Myeloid	5.5%
264	Carcinoma, Basal Cell	5.5%
265	Sarcopenia	5.4%
266	Lambert-Eaton Myasthenic Syndrome	5.3%
267	Lymphoma	5.3%
268	Adenomatous Polyposis Coli	5.3%
269	Corpus Luteum Cyst	5.2%
270	Ovarian Cysts	5.2%
271	Prolactinoma	5.1%
272	Growth Hormone-Secreting Pituitary Adenoma	5.1%
273	Astrocytoma	5.1%
274	Ependymoma	5.1%
275	oligodendroglioma	5.1%
276	Ganglioglioma	5.1%
277	gliosarcoma	5.1%
278	Anaplastic astrocytoma	5.1%
279	Anaplastic Oligodendroglioma	5.1%
280	Pituitary Adenoma	5.1%
281	Pituitary Neoplasms	5.1%
282	Mobius Syndrome	5%
283	Biliary Fistula	5%
284	Gastric Fistula	5%
285	Congenital diaphragmatic hernia	5%
286	Herpes Zoster Oticus	5%
287	Leydig Cell Tumor	5%
288	Alveolar Bone Loss	4.9%
289	Meningeal Neoplasms	4.9%
290	Left Ventricular Hypertrophy	4.9%
291	Right Ventricular Hypertrophy	4.9%
292	Herpes Labialis	4.9%
293	Gingival Hyperplasia	4.9%
294	Gingival Hypertrophy	4.9%
295	Rectal Prolapse	4.9%
296	Uterine Prolapse	4.9%
297	Trigeminal Nerve Disorder	4.9%
298	Vaginal Prolapse	4.9%
299	Temporomandibular Joint Disorders	4.9%
300	Cystadenocarcinoma	4.9%
301	Fibrosarcoma	4.9%
302	Osteosarcoma	4.9%
303	Mucoepidermoid Carcinoma	4.9%
304	Malignant Carcinoid Syndrome	4.9%
305	Opsoclonus-Myoclonus Syndrome	4.8%
306	ovarian neoplasm	4.8%
307	Toothache	4.7%
308	Postoperative Nausea and Vomiting	4.7%
309	Choledochal Cyst	4.6%
310	Adenoma	4.6%
311	Ameloblastoma	4.6%
312	Angiokeratoma	4.6%
313	Carcinoma	4.6%
314	Chordoma	4.6%
315	Hemangioma	4.6%
316	hemangiopericytoma	4.6%
317	Lymphangioma	4.6%
318	Mesenchymoma	4.6%
319	Nevus	4.6%
320	Teratoma	4.6%
321	Hepatoblastoma	4.6%
322	Mixed Tumor, Mullerian	4.6%
323	Germinoma	4.6%
324	Teratocarcinoma	4.6%
325	Angiofibroma	4.6%
326	Sarcoma	4.6%
327	Epithelioma	4.6%
328	Adenofibroma	4.6%
329	Fibroadenoma	4.6%
330	Malignant Fibrous Histiocytoma	4.6%
331	Glioblastoma	4.6%
332	Neuroblastoma	4.6%
333	Glioblastoma Multiforme	4.6%
334	granulosa cell tumor	4.6%
335	Carcinoma, Ovarian Epithelial	4.6%
336	Mesoblastic Nephroma	4.6%
337	Peutz-Jeghers Syndrome	4.6%
338	Endometrial Stromal Sarcoma	4.5%
339	Dental Pulp Necrosis	4.4%
340	Infarction	4.4%
341	Postoperative Hemorrhage	4.4%
342	Shock, Hemorrhagic	4.4%
343	Systemic Inflammatory Response Syndrome	4.4%
344	jaundice	4.4%
345	Facial Nerve Injuries	4.4%
346	Myelitis, Transverse	4.4%
347	Ganglioneuroblastoma	4.4%
348	Bowen's Disease	4.3%
349	Paraganglioma	4.3%
350	Rhabdomyosarcoma	4.3%
351	Giant Cell Tumor of Bone	4.3%
352	Bronchial Fistula	4.3%
353	Lung Neoplasms	4.3%
354	Pancreatic Fistula	4.3%
355	Pleural Neoplasms	4.3%
356	Intestinal Fistula	4.3%
357	Gastroschisis	4.3%
358	Enterocutaneous Fistula	4.3%
359	Brain Neoplasms	4.2%
360	Spinal Cord Neoplasms	4.2%
361	Cystocele	4.2%
362	Uterine Neoplasms	4.2%
363	Vaginal Neoplasms	4.2%
364	Vulvar Neoplasms	4.2%
365	Uterine Cancer	4.2%
366	Fallopian Tube Neoplasms	4.2%
367	Hydatidiform Mole	4.2%
368	Umbilical hernia	4.2%
369	Neurofibrosarcoma	4.1%
370	Lymphangioleiomyomatosis	4.1%
371	Mumps	4.1%
372	Trigeminal Neuralgia	4.1%
373	Dermatofibrosarcoma	4.1%
374	Dermatofibrosarcoma Protuberans	4.1%
375	Ascites	4%
376	Asthenia	4%
377	Body Temperature Changes	4%
378	Bruxism	4%
379	Cyanosis	4%
380	Dental Leakage	4%
381	Edema	4%
382	Failure to Thrive	4%
383	Fatigue	4%
384	Feminization	4%
385	Fetal Distress	4%
386	Fibrosis	4%
387	Gliosis	4%
388	Growth Disorders	4%
389	Head and Neck Neoplasms	4%
390	Hemorrhage	4%
391	Hyperbilirubinemia	4%
392	Hypercementosis	4%
393	Hyperplasia	4%
394	Hypomenorrhea	4%
395	Inflammation	4%
396	Intraoperative Complications	4%
397	Ischemia	4%
398	Lithiasis	4%
399	Malacoplakia	4%
400	Malocclusion	4%
401	Menstruation Disturbances	4%
402	Metaplasia	4%
403	Motion Sickness	4%
404	Nerve Degeneration	4%
405	Ochronosis	4%
406	Polymenorrhea	4%
407	Postoperative Complications	4%
408	Sclerosis	4%
409	Shock	4%
410	Signs and Symptoms, Digestive	4%
411	Signs and Symptoms, Respiratory	4%
412	Skin Manifestations	4%
413	Tooth Crowding	4%
414	Tooth Discoloration	4%
415	Ulcer	4%
416	Tooth Demineralization	4%
417	Chills	4%
418	Lassitude	4%
419	Tooth Ankylosis	4%
420	Hyperammonemia	4%
421	Hyperamylasemia	4%
422	Teratogenesis	4%
423	Cardiac Death	4%
424	Hypovolemia	4%
425	Pseudophakia	4%
426	Hyperuricemia	4%
427	Urological Manifestations	4%
428	Leukoaraiosis	4%
429	Dysbacteriosis	4%
430	Mobility Limitation	4%
431	Delayed Graft Function	4%
432	Cirrhosis	4%
433	Somnolence	4%
434	Neointima	4%
435	Dysbiosis	4%
436	Carcinoid Heart Disease	4%
437	Adrenocortical carcinoma	4%
438	Toxic Epidermal Necrolysis	3.9%
439	Stevens-Johnson Syndrome	3.9%
440	Paranasal Sinus Neoplasms	3.9%
441	Eye Hemorrhage	3.9%
442	Pancreatic Pseudocyst	3.9%
443	Plasmacytoma	3.9%
444	Abdominal Pain	3.8%
445	Malignant histiocytosis	3.8%
446	Pain, Postoperative	3.8%
447	Histiocytic sarcoma	3.8%
448	Hemoptysis	3.8%
449	Meningeal Carcinomatosis	3.8%
450	Pheochromocytoma	3.8%
451	Alveolar rhabdomyosarcoma	3.8%
452	Ecchymosis	3.8%
453	Petechiae	3.8%
454	Purpura	3.8%
455	Muscle Weakness	3.8%
456	Dental Enamel Hypoplasia	3.8%
457	Hypodontia	3.8%
458	Central Nervous System Cysts	3.7%
459	Bile Duct Neoplasms	3.7%
460	gallbladder neoplasm	3.7%
461	Intestinal Neoplasms	3.7%
462	Penile Neoplasms	3.7%
463	Prostatic Neoplasms	3.7%
464	Stomach Neoplasms	3.7%
465	Renal Colic	3.7%
466	Polycythemia Vera	3.7%
467	Denys-Drash Syndrome	3.6%
468	Dysmenorrhea	3.6%
469	Failed Back Surgery Syndrome	3.6%
470	Renal Cell Carcinoma	3.6%
471	Papillary Renal Cell Carcinoma	3.6%
472	Cell Transformation, Viral	3.5%
473	Ulcerative stomatitis	3.5%
474	Extravasation of Diagnostic and Therapeutic Materials	3.5%
475	Eye Manifestations	3.5%
476	Neurologic Manifestations	3.5%
477	Tooth Injuries	3.5%
478	Maxillary Diseases	3.4%
479	Necrosis	3.4%
480	Tooth Resorption	3.4%
481	Cardiac Output, High	3.4%
482	Myocardial Stunning	3.4%
483	Reticulocytosis	3.4%
484	Pigmentation Disorders	3.4%
485	Low Cardiac Output Syndrome	3.4%
486	Respiratory Aspiration	3.4%
487	Epistaxis	3.4%
488	Acantholysis	3.4%
489	Chromosome Aberrations	3.4%
490	Dehydration	3.4%
491	Granuloma	3.4%
492	Leukocytosis	3.4%
493	Pleocytosis	3.4%
494	Intermittent Claudication	3.3%
495	Eye pain	3.3%
496	Chromosomal Instability	3.3%
497	Jaw Abnormalities	3.3%
498	Bronchial Neoplasms	3.3%
499	Multiple Pulmonary Nodules	3.3%
500	Adenocarcinoma	3.3%
501	Carcinoma in Situ	3.3%
502	Carcinoma, Transitional Cell	3.3%
503	Phyllodes Tumor	3.3%
504	Dysgerminoma	3.3%
505	Hemangioendothelioma	3.3%
506	Lipoma	3.3%
507	Myoma	3.3%
508	Myxoma	3.3%
509	Neuroma	3.3%
510	Papilloma	3.3%
511	Pseudomyxoma Peritonei	3.3%
512	Seminoma	3.3%
513	Papillomatosis	3.3%
514	Angiolipoma	3.3%
515	Myelolipoma	3.3%
516	Neoplasms, Bone Tissue	3.3%
517	Neoplasms, Fibrous Tissue	3.3%
518	Smooth Muscle Tumor	3.3%
519	Adenomatosis, Pulmonary	3.3%
520	Adenomatous Polyps	3.3%
521	Carcinoma, Large Cell	3.3%
522	Carcinoma, Small Cell	3.3%
523	Desmoplastic Small Round Cell Tumor	3.3%
524	Chondroma	3.3%
525	Enchondroma	3.3%
526	Hodgkin Disease	3.3%
527	Lymphoma, Non-Hodgkin	3.3%
528	Urinary Bladder Fistula	3.3%
529	Bladder Neoplasm	3.3%
530	Kidney Neoplasm	3.3%
531	Ureteral Neoplasms	3.3%
532	Urethral Neoplasms	3.3%
533	Jaundice, Obstructive	3.3%
534	Menorrhagia	3.3%
535	Sudden infant death syndrome	3.3%
536	Polycystic Ovary Syndrome	3.3%
537	Retrognathia	3.3%
538	Supratentorial Neoplasms	3.3%
539	Endometrial Neoplasms	3.2%
540	Maxillary Sinus Neoplasms	3.2%
541	Carcinoma, Endometrioid	3.2%
542	Rectal Fistula	3.1%
543	Anal Fistula	3.1%
544	Prognathism	3%
545	Abdomen, Acute	3%
546	Sicca Syndrome	3%
547	Sjogren's Syndrome	3%
548	Genomic Instability	3%
549	Nasopharyngitis	3%
550	Arteriovenous fistula	2.9%
551	Pharyngitis	2.9%
552	Hypergammaglobulinemia	2.9%
553	Phantom pain	2.9%
554	Phantom Limb Pain	2.9%
555	Primary amyloidosis	2.9%
556	Pleural Effusion, Malignant	2.9%
557	Prostatic Neoplasms, Castration-Resistant	2.9%
558	Nelson Syndrome	2.8%
559	Azotemia	2.8%
560	Leukoplakia	2.8%
561	Hematemesis	2.8%
562	Temporomandibular Joint Dysfunction Syndrome	2.8%
563	Purpura Fulminans	2.8%
564	Brain Stem Neoplasms	2.8%
565	Leukemia, Myelomonocytic, Chronic	2.7%
566	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	2.7%
567	Kidney Calculi	2.7%
568	Ureteral Calculi	2.7%
569	Acute Disease	2.6%
570	Acute-Phase Reaction	2.6%
571	Amenorrhea	2.6%
572	Anorexia	2.6%
573	Anoxia	2.6%
574	Chronic disease	2.6%
575	Constipation	2.6%
576	Critical Illness	2.6%
577	Sudden death	2.6%
578	Dental caries	2.6%
579	Dental Plaque	2.6%
580	Dental Pulp Calcification	2.6%
581	Diarrhea	2.6%
582	Dyspepsia	2.6%
583	Eructation	2.6%
584	Fat necrosis	2.6%
585	Fever	2.6%
586	Flatulence	2.6%
587	Flushing	2.6%
588	Gangrene	2.6%
589	Graft Occlusion, Vascular	2.6%
590	Granuloma, Plasma Cell	2.6%
591	Halitosis	2.6%
592	Heartburn	2.6%
593	Hematoma	2.6%
594	Hiccough	2.6%
595	Hypercalciuria	2.6%
596	Hypercapnia	2.6%
597	Hyperphagia	2.6%
598	Iatrogenic Disease	2.6%
599	Multiple Organ Failure	2.6%
600	Nausea	2.6%
601	Oligomenorrhea	2.6%
602	Pallor	2.6%
603	Premenstrual syndrome	2.6%
604	Psychophysiologic Disorders	2.6%
605	Pulpitis	2.6%
606	Recurrence	2.6%
607	Retrograde Degeneration	2.6%
608	Retroperitoneal fibrosis	2.6%
609	Serositis	2.6%
610	Subcutaneous Emphysema	2.6%
611	Surgical Wound Dehiscence	2.6%
612	Syndrome	2.6%
613	Tooth Erosion	2.6%
614	Vomiting	2.6%
615	Wallerian Degeneration	2.6%
616	Hypocapnia	2.6%
617	Pyogenic granuloma	2.6%
618	Exsanguination	2.6%
619	Dyschezia	2.6%
620	Hypoxia	2.6%
621	Disease Progression	2.6%
622	Hyperoxia	2.6%
623	Seroma	2.6%
624	Premenstrual Tension	2.6%
625	Delayed Emergence from Anesthesia	2.6%
626	Infant Death	2.6%
627	Lower Urinary Tract Symptoms	2.6%
628	Hypoxemia	2.6%
629	Anastomotic Leak	2.6%
630	Intraoperative Awareness	2.6%
631	Urinoma	2.6%
632	Adenoid Cystic Carcinoma	2.6%
633	fibroma	2.6%
634	Fibromatosis	2.6%
635	Osteoblastoma	2.6%
636	Osteoma	2.6%
637	Rhabdomyoma	2.6%
638	Chondromatosis	2.6%
639	Adenocarcinoma, Clear Cell	2.6%
640	Cholangiocarcinoma	2.6%
641	Cervical Intraepithelial Neoplasia	2.6%
642	Hemangioblastoma	2.6%
643	Lymphoma, Extranodal NK-T-Cell	2.6%
644	Endotoxic shock	2.6%
645	Septic Shock	2.6%
646	Toxic Shock Syndrome	2.6%
647	Cardiotoxicity	2.5%
648	Choroid Plexus Papilloma	2.5%
649	Cecal Neoplasms	2.5%
650	Duodenal Neoplasms	2.5%
651	Maxillofacial Abnormalities	2.5%
652	Leukoplakia, Oral	2.5%
653	Chromosome Fragility	2.5%
654	Cerebellar Neoplasms	2.4%
655	Mastocytosis	2.4%
656	Sturge-Weber Syndrome	2.4%
657	Gastrointestinal Stromal Tumors	2.4%
658	Hemangioma, Cavernous	2.3%
659	Leukemia, T-Cell	2.3%
660	Leukemia, B-Cell	2.3%
661	Hoarseness	2.3%
662	neurofibroma	2.3%
663	Lymphoma, Follicular	2.3%
664	T-Cell Lymphoma	2.3%
665	Mantle cell lymphoma	2.3%
666	Waldenstrom Macroglobulinemia	2.3%
667	Multiple Myeloma	2.3%
668	Fibromatosis, Aggressive	2.3%
669	Fibromatosis, Abdominal	2.3%
670	Klatskin Tumor	2.3%
671	Asphyxia	2.3%
672	Granuloma, Respiratory Tract	2.3%
673	Shock, Traumatic	2.3%
674	Micrognathism	2.3%
675	Pierre Robin Syndrome	2.3%
676	Colorectal Neoplasms	2.3%
677	Gait Ataxia	2.2%
678	Apnea	2.2%
679	Cheyne-Stokes Respiration	2.2%
680	Decerebrate State	2.2%
681	Disease susceptibility	2.2%
682	Dyspnea	2.2%
683	Fetal Death	2.2%
684	Foreign-Body Reaction	2.2%
685	Gastrointestinal Hemorrhage	2.2%
686	Hemarthrosis	2.2%
687	Hemiparesis	2.2%
688	Hemoperitoneum	2.2%
689	Hemothorax	2.2%
690	Hyperventilation	2.2%
691	Meningism	2.2%
692	Mouth Breathing	2.2%
693	Mouth Neoplasms	2.2%
694	Paresis	2.2%
695	Postpericardiotomy Syndrome	2.2%
696	Prosthesis Failure	2.2%
697	Pruritus	2.2%
698	Reperfusion Injury	2.2%
699	Seizures	2.2%
700	Sensation Disorders	2.2%
701	Sneezing	2.2%
702	Tooth Avulsion	2.2%
703	Erythema	2.2%
704	Complex partial seizures	2.2%
705	Injection Site Reaction	2.2%
706	Necrolytic Migratory Erythema	2.2%
707	Tachypnea	2.2%
708	Monoparesis	2.2%
709	Retrobulbar Hemorrhage	2.2%
710	Aseptic Necrosis of Bone	2.2%
711	Peritoneal Fibrosis	2.2%
712	Neurogenic Inflammation	2.2%
713	Perinatal death	2.2%
714	Gait Disorders, Neurologic	2.2%
715	Neuromuscular Manifestations	2.2%
716	Infusion site reaction	2.2%
717	Nephrogenic Fibrosing Dermopathy	2.2%
718	Corneal Endothelial Cell Loss	2.2%
719	Encapsulating Peritoneal Sclerosis	2.2%
720	Vasoplegia	2.2%
721	Suppuration	2.2%
722	Nephrogenic Systemic Fibrosis	2.2%
723	Thrombocytopenic purpura	2.2%
724	Sinus Arrhythmia	2.2%
725	Atrial Fibrillation	2.2%
726	Atrial Flutter	2.2%
727	Edema, Cardiac	2.2%
728	Mental Fatigue	2.2%
729	Granuloma, Foreign-Body	2.2%
730	Hirsutism	2.2%
731	Mediastinal Emphysema	2.2%
732	Surgical Wound Infection	2.2%
733	Ventricular Fibrillation	2.2%
734	Ventricular Flutter	2.2%
735	Parasystole	2.2%
736	Paroxysmal atrial fibrillation	2.2%
737	Facies	2.2%
738	Bradycardia	2.2%
739	Embryo Loss	2.2%
740	Orthostatic intolerance	2.2%
741	Hypoventilation	2.2%
742	Afferent Loop Syndrome	2.2%
743	Sex Chromosome Aberrations	2.2%
744	Short Bowel Syndrome	2.2%
745	Uterine hemorrhage	2.2%
746	No-Reflow Phenomenon	2.2%
747	Body Weight	2.2%
748	Body Weight Changes	2.2%
749	Mastocytoma	2.2%
750	Purpura, Hyperglobulinemic	2.2%
751	Mastocytosis, Systemic	2.2%
752	Leukemia, Myeloid, Chronic-Phase	2.2%
753	Sick Sinus Syndrome	2.2%
754	Trisomy	2.2%
755	Appendiceal Neoplasms	2.2%
756	Colonic Neoplasms	2.2%
757	Rectal Neoplasms	2.2%
758	Zollinger-Ellison syndrome	2.1%
759	Sleep Wake Disorders	2%
760	Akathisia	2%
761	Restlessness	2%
762	Psychomotor Agitation	2%
763	Lemierre Syndrome	2%
764	Tissue Adhesions	2%
765	Back Pain	2%
766	Bulimia	2%
767	Neck Pain	2%
768	Chest Pain	2%
769	Dizziness	2%
770	Dysuria	2%
771	Facial Pain	2%
772	Fever of Unknown Origin	2%
773	Flank Pain	2%
774	Headache	2%
775	Nocturia	2%
776	Pain, Intractable	2%
777	Pelvic Pain	2%
778	Snoring	2%
779	Chronic pain	2%
780	Lightheadedness	2%
781	Pain, Referred	2%
782	Prostatism	2%
783	Throbbing Headache	2%
784	Labor Pain	2%
785	Cancer Pain	2%
786	Hematoma, Epidural, Spinal	2%
787	Nociceptive Pain	2%
788	Pupil Disorders	2%
789	Neurobehavioral Manifestations	2%
790	Drowning	2%
791	Hematoma, Subdural	1.9%
792	Hematoma, Epidural, Cranial	1.9%
793	Fetal Growth Retardation	1.9%
794	Pleural Rub	1.9%
795	Rales	1.9%
796	Respiratory Sounds	1.9%
797	Rhonchi	1.9%
798	Stridor	1.9%
799	Wheezing	1.9%
800	Asterixis	1.9%
801	Ballismus	1.9%
802	DNA Degradation, Necrotic	1.9%
803	Aneuploidy	1.9%
804	Polyploidy	1.9%
805	Vertigo	1.9%
806	Microsatellite Instability	1.9%
807	Gait Apraxia	1.9%
808	Heart Block	1.9%
809	Pain	1.9%
810	Tachycardia	1.9%
811	Tonsillitis	1.9%
812	Tachyarrhythmia	1.9%
813	Livedo Reticularis	1.9%
814	Ache	1.9%
815	Sleep Bruxism	1.9%
816	Cicatrix	1.9%
817	Hematuria	1.9%
818	Oliguria	1.9%
819	Polyuria	1.9%
820	Proteinuria	1.9%
821	Granuloma Annulare	1.9%
822	Chromosome Breakage	1.9%
823	Brain Death	1.9%
824	Shock, Cardiogenic	1.9%
825	Underweight	1.9%
826	Overweight	1.9%
827	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	1.9%
828	Leukemia, Large Granular Lymphocytic	1.9%
829	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	1.9%
830	Lymphoma, T-Cell, Cutaneous	1.9%
831	Lymphoma, AIDS-Related	1.9%
832	Enteropathy-Associated T-Cell Lymphoma	1.9%
833	Primary Effusion Lymphoma	1.9%
834	Purpura, Thrombotic Thrombocytopenic	1.8%
835	Anus Neoplasms	1.8%
836	Sigmoid Neoplasms	1.8%
837	Voice Disorders	1.7%
838	Voice Disturbance	1.7%
839	Gagging	1.7%
840	Cross Infection	1.7%
841	Hyphema	1.7%
842	Retinal Neovascularization	1.7%
843	Septicemia	1.7%
844	Vitreous Hemorrhage	1.7%
845	Sepsis	1.7%
846	Morning Sickness	1.7%
847	Dupuytren Contracture	1.7%
848	Long QT Syndrome	1.7%
849	Retropharyngeal Abscess	1.7%
850	Abscess	1.6%
851	Anosmia	1.6%
852	Ataxia	1.6%
853	Athetosis	1.6%
854	Catalepsy	1.6%
855	Dystonia	1.6%
856	Empyema	1.6%
857	Femur Head Necrosis	1.6%
858	Fetal Resorption	1.6%
859	Hemiplegia	1.6%
860	Locked-In Syndrome	1.6%
861	Muscle Hypertonia	1.6%
862	Muscle hypotonia	1.6%
863	Myoclonus	1.6%
864	Myotonia	1.6%
865	Neuralgia	1.6%
866	Paraplegia	1.6%
867	Peptic Ulcer Hemorrhage	1.6%
868	Pseudobulbar Palsy	1.6%
869	Quadriplegia	1.6%
870	Spasm	1.6%
871	Spastic Paraplegia	1.6%
872	Status Epilepticus	1.6%
873	Taste Disorders	1.6%
874	Tremor	1.6%
875	Sudden Cardiac Death	1.6%
876	Monoplegia	1.6%
877	Hypokinesia	1.6%
878	Gastroparesis	1.6%
879	Paraparesis	1.6%
880	Bradykinesia	1.6%
881	Waxy flexibility	1.6%
882	Action Tremor	1.6%
883	Resting Tremor	1.6%
884	Dysosmia	1.6%
885	Quadriparesis	1.6%
886	Premenstrual Dysphoric Disorder	1.6%
887	Olfaction Disorders	1.6%
888	Choroidal Neovascularization	1.6%
889	Myokymia	1.6%
890	Somatosensory Disorders	1.6%
891	Primary Graft Dysfunction	1.6%
892	Neuropathic pain	1.6%
893	Hyperkinesia	1.6%
894	Intention tremor	1.6%
895	Dumping Syndrome	1.6%
896	Emaciation	1.6%
897	Low Back Pain	1.6%
898	Cicatrix, Hypertrophic	1.6%
899	Visceral Pain	1.6%
900	Hematoma, Subdural, Spinal	1.6%
901	Sinus Arrest, Cardiac	1.6%
902	Urticaria Pigmentosa	1.6%
903	Metrorrhagia	1.6%
904	Micronuclei, Chromosome-Defective	1.6%
905	Weight Gain	1.6%
906	Alice in Wonderland Syndrome	1.6%
907	Alexia	1.6%
908	Dyslexia	1.6%
909	Mycosis Fungoides	1.6%
910	Lymphomatoid Papulosis	1.6%
911	Plasmablastic lymphoma	1.6%
912	Hematoma, Subdural, Intracranial	1.6%
913	Hematoma, Subdural, Chronic	1.6%
914	Hematoma, Subdural, Acute	1.6%
915	Autoimmune thrombocytopenia	1.5%
916	Immune thrombocytopenic purpura	1.5%
917	Waterhouse-Friderichsen Syndrome	1.5%
918	Subacute Combined Degeneration	1.5%
919	Jet Lag Syndrome	1.5%
920	Cachexia	1.5%
921	Eosinophilic Granuloma	1.5%
922	Reflex, Abnormal	1.5%
923	Hyporeflexia	1.5%
924	Hyperreflexia	1.5%
925	Vision Disorders	1.5%
926	Metamorphopsia	1.5%
927	Visual Impairment	1.5%
928	Burkitt Lymphoma	1.4%
929	Metatarsalgia	1.4%
930	Retinal Hemorrhage	1.4%
931	Birth Weight	1.4%
932	Anisocoria	1.4%
933	Choroid Hemorrhage	1.4%
934	Confusion	1.4%
935	Lethargy	1.4%
936	Melena	1.4%
937	Memory Disorders	1.4%
938	Muscle Cramp	1.4%
939	Perceptual Disorders	1.4%
940	Psychomotor Disorders	1.4%
941	Tonic Pupil	1.4%
942	Anhedonia	1.4%
943	Disorientation	1.4%
944	Fetal Hypoxia	1.4%
945	Memory Loss	1.4%
946	Hemisensory Neglect	1.4%
947	Dysacusis	1.4%
948	Viremia	1.4%
949	Parasitemia	1.4%
950	Dyspnea, Paroxysmal	1.4%
951	Mastodynia	1.4%
952	Postpartum Hemorrhage	1.4%
953	Respiratory Paralysis	1.4%
954	Chorea	1.4%
955	Keloid	1.4%
956	Tetany	1.4%
957	Urinary Incontinence	1.4%
958	Breakthrough Pain	1.4%
959	Monosomy	1.4%
960	Tetraploidy	1.4%
961	Stillbirth	1.4%
962	Adams-Stokes Syndrome	1.4%
963	Atrioventricular Block	1.4%
964	Bundle-Branch Block	1.4%
965	Atrial Premature Complexes	1.4%
966	Sinoatrial Block	1.4%
967	Tachycardia, Paroxysmal	1.4%
968	Supraventricular tachycardia	1.4%
969	Tachycardia, Ventricular	1.4%
970	Tachycardia, Reciprocating	1.4%
971	Albuminuria	1.4%
972	Hemoglobinuria	1.4%
973	Subarachnoid Hemorrhage	1.4%
974	Cerebral Hemorrhage	1.4%
975	Hyperemesis Gravidarum	1.4%
976	Dysgeusia	1.4%
977	Formication	1.4%
978	Hyperalgesia	1.4%
979	Hyperesthesia	1.4%
980	Hypesthesia	1.4%
981	Language Disorders	1.4%
982	Numbness	1.4%
983	Paresthesia	1.4%
984	Paraparesis, Spastic	1.4%
985	Trismus	1.4%
986	Epilepsia Partialis Continua	1.4%
987	Hypogeusia	1.4%
988	Brown-Sequard Syndrome	1.4%
989	Lockjaw	1.4%
990	Allodynia	1.4%
991	Ageusia	1.4%
992	Kernicterus	1.3%
993	Sezary Syndrome	1.3%
994	Consciousness Disorders	1.3%
995	Mental Retardation	1.3%
996	Depressed Level of Consciousness	1.3%
997	Mental deficiency	1.3%
998	Intellectual Disability	1.3%
999	Catatonia	1.3%
1000	Cellulitis	1.3%
1001	Musculoskeletal Pain	1.3%
1002	Ophthalmoplegia	1.3%
1003	External Ophthalmoplegia	1.3%
1004	Aphonia	1.2%
1005	Arthralgia	1.2%
1006	Sleep Deprivation	1.2%
1007	Polyarthralgia	1.2%
1008	Dysphonia	1.2%
1009	Cerebrospinal Fluid Otorrhea	1.2%
1010	Cerebrospinal Fluid Rhinorrhea	1.2%
1011	Peritonsillar Abscess	1.2%
1012	Romano-Ward Syndrome	1.2%
1013	Agraphia	1.2%
1014	Anomia	1.2%
1015	Cluttering	1.2%
1016	Language Development Disorders	1.2%
1017	Speech Disorders	1.2%
1018	Syncope	1.2%
1019	Stupor	1.2%
1020	Dysgraphia	1.2%
1021	Presyncope	1.2%
1022	Dyslalia	1.2%
1023	Obesity	1.2%
1024	Hydrops Fetalis	1.2%
1025	Bacteremia	1.2%
1026	Fetal Weight	1.2%
1027	Diplopia	1.2%
1028	Muscle Rigidity	1.2%
1029	Muscle Spasticity	1.2%
1030	Scotoma	1.2%
1031	Photophobia	1.2%
1032	Cogwheel Rigidity	1.2%
1033	Amaurosis	1.2%
1034	Blindness	1.2%
1035	Nuchal Rigidity	1.2%
1036	Angina Pectoris	1.2%
1037	Fungemia	1.2%
1038	Agnosia	1.2%
1039	Apraxias	1.2%
1040	Hallucinations	1.2%
1041	Hemianopsia	1.2%
1042	Hyperacusis	1.2%
1043	Tinnitus	1.2%
1044	Visual Agnosia	1.2%
1045	Anosognosia	1.2%
1046	Wernicke-Korsakoff Syndrome	1.2%
1047	Phonophobia	1.2%
1048	Hearing Loss	1.2%
1049	Cerebellar Ataxia	1.2%
1050	Torticollis	1.2%
1051	Sciatica	1.2%
1052	Urge Incontinence	1.2%
1053	Tardive Dyskinesia	1.2%
1054	Tachycardia, Atrioventricular Nodal Reentry	1.2%
1055	Tachycardia, Ectopic Atrial	1.2%
1056	Tachycardia, Ectopic Junctional	1.2%
1057	Sinus Tachycardia	1.2%
1058	Torsades de Pointes	1.2%
1059	Accelerated Idioventricular Rhythm	1.2%
1060	Aphasia	1.2%
1061	Articulation Disorders	1.2%
1062	Echolalia	1.2%
1063	Stuttering	1.2%
1064	Dysphasia	1.2%
1065	Granuloma, Laryngeal	1.1%
1066	Vocal Cord Paralysis	1.1%
1067	Dysarthria	1.1%
1068	Myocardial Reperfusion Injury	1.1%
1069	Tinea Pedis	1.1%
1070	Endotoxemia	1.1%
1071	Amaurosis Fugax	1.1%
1072	Blindness, Cortical	1.1%
1073	Dyscalculia	1.1%
1074	Angina, Unstable	1%
1075	Deafness	1%
1076	Hearing Loss, Sudden	1%
1077	Gerstmann Syndrome	1%
1078	Hearing Loss, Bilateral	1%
1079	Hearing Loss, High-Frequency	1%
1080	Hearing Loss, Mixed Conductive-Sensorineural	1%
1081	Prosopagnosia	1%
1082	Apraxia, Ideomotor	1%
1083	Persistent Vegetative State	1%
1084	Charles Bonnet Syndrome	1%
1085	Hearing Loss, Unilateral	1%
1086	Complete Hearing Loss	1%
1087	Alien Hand Syndrome	1%
1088	Deaf Mutism	1%
1089	Amblyopia	1%
1090	Amnesia	1%
1091	Delirium	1%
1092	Horner Syndrome	1%
1093	Dissociative Amnesia	1%
1094	Color blindness	1%
1095	Global Amnesia	1%
1096	Shoulder Pain	1%
1097	Pediatric Obesity	1%
1098	Dyskinesia, Drug-Induced	1%
1099	Mutism	1%
1100	Selective Mutism	1%
1101	Alcohol Withdrawal Seizures	1%
1102	Angina Pectoris, Variant	1%
1103	Philadelphia Chromosome	1%
1104	Alexia, Pure	1%
1105	Akathisia, Drug-Induced	0.9%
1106	Retrograde amnesia	0.9%
1107	Myalgia	0.9%
1108	Amnesia, Anterograde	0.9%
1109	Auditory Perceptual Disorders	0.8%
1110	Amnesia, Transient Global	0.8%
1111	Candidemia	0.8%
1112	Basal Ganglia Hemorrhage	0.8%
1113	Ophthalmoplegic Migraine	0.8%
1114	Progressive supranuclear palsy	0.7%
1115	Putaminal Hemorrhage	0.7%
1116	Kearns-Sayre syndrome	0.5%

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