MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Muscle Hypertonia

(UMLS:C0026826)

Definition:: Abnormal increase in skeletal or smooth muscle tone. Skeletal muscle hypertonicity may be associated with PYRAMIDAL TRACT lesions or BASAL GANGLIA DISEASES.
UMLS ID:: C0026826
MeSH ID:: D009122

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.597.613.550

Classification 2:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.888.592.608.550

Synonym(s)

Muscle Hypertonia

HYPERTONIA

High muscle tone

Hypertonia

Hypertonia, NOS

Hypertonicity

Hypertonus, muscular

Increased Muscle Tone

Increased muscle tone

10.

Muscle hypertonia

11.

Muscle hypertonicity

12.

Muscular hypertonicity

13.

Muscular hypertonus

14.

Scottie cramp

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Amitriptyline	7775702	CTD
2	Baclofen	4266642	CTD
3	Clomipramine	7058100	CTD
4	Cocaine	8499039 9917443	CTD
5	Dantrolene	7079122	CTD
6	Desipramine	5526730	CTD
7	Diazepam	5443419 6928283 12365318	CTD
8	Dinoprostone	4135526	CTD
9	Droperidol	12378031	CTD
10	Enalapril	2404862	CTD
11	Etretinate	3711400	CTD
12	Haloperidol	5526730 10847307	CTD
13	Mandrax	5443419	CTD
14	Meperidine	6963160	CTD
15	Methylergonovine	3172085	CTD
16	Metoclopramide	601923 831335 2594559	CTD
17	Mifepristone	11435005	CTD
18	Morphine	6110016	CTD
19	Olanzapine	10847307 10997865	CTD
20	Orphenadrine	216517	CTD
21	Phenytoin	3994321	CTD
22	Prochlorperazine	216517	CTD
23	Promethazine	6963160	CTD
24	Propofol	2386278	CTD
25	Risperidone	10847307	CTD
26	Succinylcholine	7171420 7941938	CTD
27	Sulpiride	6110016	CTD
28	Thioridazine	3390252	CTD
29	cyamemazine	6110016	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Muscle hypotonia	47.5%
2	Myotonia	47.5%
3	Spasm	47.5%
4	Myokymia	47.5%
5	Muscular Atrophy	40.1%
6	Muscle Cramp	38.7%
7	Tetany	37.9%
8	Muscle Weakness	35.4%
9	Trismus	35.2%
10	Lockjaw	35.2%
11	Decerebrate State	32.8%
12	Hemiparesis	32.8%
13	Meningism	32.8%
14	Paresis	32.8%
15	Seizures	32.8%
16	Sensation Disorders	32.8%
17	Complex partial seizures	32.8%
18	Monoparesis	32.8%
19	Gait Disorders, Neurologic	32.8%
20	Sarcopenia	29.4%
21	Asterixis	28.9%
22	Ballismus	28.9%
23	Hemifacial Spasm	28.7%
24	Pupil Disorders	27.3%
25	Neurobehavioral Manifestations	27.3%
26	Vertigo	26%
27	Gait Ataxia	24.7%
28	Psychophysiologic Disorders	23.1%
29	Sleep Wake Disorders	22.3%
30	Voice Disorders	22.3%
31	Voice Disturbance	22.3%
32	Anosmia	21.3%
33	Ataxia	21.3%
34	Athetosis	21.3%
35	Catalepsy	21.3%
36	Dystonia	21.3%
37	Hemiplegia	21.3%
38	Locked-In Syndrome	21.3%
39	Myoclonus	21.3%
40	Paraplegia	21.3%
41	Pseudobulbar Palsy	21.3%
42	Quadriplegia	21.3%
43	Spastic Paraplegia	21.3%
44	Status Epilepticus	21.3%
45	Taste Disorders	21.3%
46	Tremor	21.3%
47	Monoplegia	21.3%
48	Hypokinesia	21.3%
49	Paraparesis	21.3%
50	Bradykinesia	21.3%
51	Waxy flexibility	21.3%
52	Action Tremor	21.3%
53	Resting Tremor	21.3%
54	Dysosmia	21.3%
55	Quadriparesis	21.3%
56	Olfaction Disorders	21.3%
57	Somatosensory Disorders	21.3%
58	Hyperkinesia	21.3%
59	Intention tremor	21.3%
60	Akathisia	21.2%
61	Restlessness	21.2%
62	Psychomotor Agitation	21.2%
63	Orthostatic intolerance	20.7%
64	Gait Apraxia	19.5%
65	Chorea	19%
66	Abdominal Pain	18.9%
67	Reflex, Abnormal	18.4%
68	Hyporeflexia	18.4%
69	Hyperreflexia	18.4%
70	Vision Disorders	17.8%
71	Metamorphopsia	17.8%
72	Visual Impairment	17.8%
73	Neurogenic Inflammation	17.6%
74	Anisocoria	17.3%
75	Confusion	17.3%
76	Facial paralysis	17.3%
77	Lethargy	17.3%
78	Memory Disorders	17.3%
79	Perceptual Disorders	17.3%
80	Psychomotor Disorders	17.3%
81	Tonic Pupil	17.3%
82	Anhedonia	17.3%
83	Disorientation	17.3%
84	Facial Paresis	17.3%
85	Memory Loss	17.3%
86	Hemisensory Neglect	17.3%
87	Dysacusis	17.3%
88	Respiratory Paralysis	17.1%
89	Polydipsia	17.1%
90	Asthenia	16.9%
91	Body Temperature Changes	16.9%
92	Cyanosis	16.9%
93	Edema	16.9%
94	Failure to Thrive	16.9%
95	Fatigue	16.9%
96	Feminization	16.9%
97	Fetal Distress	16.9%
98	Motion Sickness	16.9%
99	Signs and Symptoms, Digestive	16.9%
100	Signs and Symptoms, Respiratory	16.9%
101	Skin Manifestations	16.9%
102	Chills	16.9%
103	Lassitude	16.9%
104	Pseudophakia	16.9%
105	Urological Manifestations	16.9%
106	Mobility Limitation	16.9%
107	Somnolence	16.9%
108	Ophthalmoplegia	16.7%
109	External Ophthalmoplegia	16.7%
110	Alice in Wonderland Syndrome	16.6%
111	Renal Colic	15.9%
112	Dysgeusia	15.8%
113	Formication	15.8%
114	Hyperalgesia	15.8%
115	Hyperesthesia	15.8%
116	Hypesthesia	15.8%
117	Language Disorders	15.8%
118	Numbness	15.8%
119	Paresthesia	15.8%
120	Paraparesis, Spastic	15.8%
121	Epilepsia Partialis Continua	15.8%
122	Hypogeusia	15.8%
123	Brown-Sequard Syndrome	15.8%
124	Allodynia	15.8%
125	Ageusia	15.8%
126	Cerebrospinal Fluid Otorrhea	15.8%
127	Cerebrospinal Fluid Rhinorrhea	15.8%
128	Eye pain	15.3%
129	Back Pain	15.2%
130	Neck Pain	15.2%
131	Chest Pain	15.2%
132	Dizziness	15.2%
133	Facial Pain	15.2%
134	Flank Pain	15.2%
135	Headache	15.2%
136	Pain, Intractable	15.2%
137	Pelvic Pain	15.2%
138	Chronic pain	15.2%
139	Lightheadedness	15.2%
140	Pain, Referred	15.2%
141	Throbbing Headache	15.2%
142	Labor Pain	15.2%
143	Cancer Pain	15.2%
144	Nociceptive Pain	15.2%
145	Alexia	14.9%
146	Dyslexia	14.9%
147	Phantom pain	14.8%
148	Phantom Limb Pain	14.8%
149	Neuralgia	14.8%
150	Neuropathic pain	14.8%
151	Dyskinesia, Drug-Induced	14.6%
152	Consciousness Disorders	14.6%
153	Mental Retardation	14.6%
154	Depressed Level of Consciousness	14.6%
155	Mental deficiency	14.6%
156	Intellectual Disability	14.6%
157	Hoarseness	14.6%
158	Cerebellar Ataxia	14.6%
159	Torticollis	14.6%
160	Catatonia	14.4%
161	Vocal Cord Paralysis	14.4%
162	Aphonia	14.3%
163	Dysphonia	14.3%
164	Tardive Dyskinesia	14.2%
165	Horner Syndrome	14%
166	Pain, Postoperative	13.9%
167	Pain	13.9%
168	Ache	13.9%
169	Ophthalmoplegic Migraine	13.5%
170	Abdomen, Acute	13.4%
171	Eye Manifestations	13.3%
172	Agraphia	13.1%
173	Anomia	13.1%
174	Cluttering	13.1%
175	Language Development Disorders	13.1%
176	Speech Disorders	13.1%
177	Syncope	13.1%
178	Stupor	13.1%
179	Dysgraphia	13.1%
180	Presyncope	13.1%
181	Dyslalia	13.1%
182	Amblyopia	12.9%
183	Diplopia	12.9%
184	Scotoma	12.9%
185	Photophobia	12.9%
186	Amaurosis	12.9%
187	Blindness	12.9%
188	Cardiac Output, High	12.8%
189	Myocardial Stunning	12.8%
190	Reticulocytosis	12.8%
191	Low Cardiac Output Syndrome	12.8%
192	Agnosia	12.7%
193	Apraxias	12.7%
194	Hallucinations	12.7%
195	Hemianopsia	12.7%
196	Hyperacusis	12.7%
197	Tinnitus	12.7%
198	Visual Agnosia	12.7%
199	Anosognosia	12.7%
200	Wernicke-Korsakoff Syndrome	12.7%
201	Phonophobia	12.7%
202	Hearing Loss	12.7%
203	Intermittent Claudication	12.5%
204	Persistent Vegetative State	12.4%
205	Alcohol Withdrawal Seizures	12.3%
206	Progressive supranuclear palsy	12.2%
207	Cranial nerve diseases	11.8%
208	Demyelinating Diseases	11.8%
209	Demyelination	11.8%
210	Neuromuscular Diseases	11.8%
211	Chronobiology Disorders	11.8%
212	Aphasia	11.7%
213	Articulation Disorders	11.7%
214	Echolalia	11.7%
215	Stuttering	11.7%
216	Dysphasia	11.7%
217	Gastroparesis	11.5%
218	Low Back Pain	11.4%
219	Visceral Pain	11.4%
220	Dysarthria	11.1%
221	Dysmenorrhea	11%
222	Failed Back Surgery Syndrome	11%
223	Amnesia	10.7%
224	Delirium	10.7%
225	Dissociative Amnesia	10.7%
226	Color blindness	10.7%
227	Global Amnesia	10.7%
228	Pathological Conditions, Anatomical	10.6%
229	Amaurosis Fugax	10.5%
230	Blindness, Cortical	10.5%
231	Dyscalculia	10.5%
232	Deafness	10.5%
233	Hearing Loss, Sudden	10.5%
234	Gerstmann Syndrome	10.5%
235	Hearing Loss, Bilateral	10.5%
236	Hearing Loss, High-Frequency	10.5%
237	Hearing Loss, Mixed Conductive-Sensorineural	10.5%
238	Prosopagnosia	10.5%
239	Apraxia, Ideomotor	10.5%
240	Charles Bonnet Syndrome	10.5%
241	Hearing Loss, Unilateral	10.5%
242	Complete Hearing Loss	10.5%
243	Alien Hand Syndrome	10.5%
244	Deaf Mutism	10.5%
245	Sciatica	10.3%
246	Motor Neuron Disease	10.3%
247	Hypergammaglobulinemia	10.2%
248	jaundice	9.9%
249	Anorexia	9.9%
250	Anoxia	9.9%
251	Constipation	9.9%
252	Diarrhea	9.9%
253	Dyspepsia	9.9%
254	Eructation	9.9%
255	Fever	9.9%
256	Flatulence	9.9%
257	Flushing	9.9%
258	Halitosis	9.9%
259	Heartburn	9.9%
260	Hiccough	9.9%
261	Hypercalciuria	9.9%
262	Hypercapnia	9.9%
263	Hyperphagia	9.9%
264	Nausea	9.9%
265	Pallor	9.9%
266	Sleep Deprivation	9.9%
267	Vomiting	9.9%
268	Hypocapnia	9.9%
269	Dyschezia	9.9%
270	Hypoxia	9.9%
271	Hyperoxia	9.9%
272	Lower Urinary Tract Symptoms	9.9%
273	Hypoxemia	9.9%
274	Urinoma	9.9%
275	Akathisia, Drug-Induced	9.8%
276	Postoperative Nausea and Vomiting	9.8%
277	Mutism	9.6%
278	Selective Mutism	9.6%
279	Metatarsalgia	9.5%
280	Multiple System Atrophy	9.4%
281	Amnesia, Transient Global	9.4%
282	Mastodynia	9.2%
283	Trauma, Nervous System	9.2%
284	Auditory Perceptual Disorders	9.2%
285	Breakthrough Pain	9.2%
286	Subacute Combined Degeneration	9.1%
287	Stiff-Person Syndrome	9%
288	Brain Death	9%
289	Alexia, Pure	8.9%
290	Nervous System Neoplasms	8.8%
291	Neurotoxicity Syndromes	8.8%
292	Retrograde amnesia	8.8%
293	Amnesia, Anterograde	8.8%
294	Toothache	8.7%
295	Jet Lag Syndrome	8.5%
296	Ocular Motility Disorders	8.5%
297	Cyclophoria	8.5%
298	Polyradiculoneuropathy	8.4%
299	Polyradiculoneuritis	8.4%
300	Encephalomyelitis	8.4%
301	Prion Diseases	8.4%
302	Autonomic Dysreflexia	8.4%
303	Complex Regional Pain Syndromes	8.4%
304	Eye Hemorrhage	8.3%
305	Restless Legs Syndrome	8.2%
306	Hemoptysis	8.1%
307	Ecchymosis	7.9%
308	Spinal Muscular Atrophy	7.9%
309	Petechiae	7.9%
310	Purpura	7.9%
311	Progressive Muscular Atrophy	7.9%
312	Musculoskeletal Pain	7.8%
313	Opsoclonus-Myoclonus Syndrome	7.7%
314	Arthralgia	7.7%
315	Polyarthralgia	7.7%
316	Meningoencephalitis	7.7%
317	Parkinson Disease	7.6%
318	Apnea	7.6%
319	Cheyne-Stokes Respiration	7.6%
320	Dyspnea	7.6%
321	Hyperventilation	7.6%
322	Mouth Breathing	7.6%
323	Pruritus	7.6%
324	Sneezing	7.6%
325	Erythema	7.6%
326	Necrolytic Migratory Erythema	7.6%
327	Tachypnea	7.6%
328	Amyotrophic Lateral Sclerosis	7.5%
329	Marchiafava-Bignami Disease	7.5%
330	Edema, Cardiac	7.4%
331	Mental Fatigue	7.4%
332	Hirsutism	7.4%
333	Hypoventilation	7.4%
334	Body Weight Changes	7.3%
335	Coma, Post-Head Injury	7%
336	Body Weight	7%
337	Spinal Cord Injuries	7%
338	Vascular Remodeling	6.9%
339	Angina Pectoris	6.9%
340	Myalgia	6.8%
341	Lewy Body Disease	6.8%
342	Peripheral Nerve Injuries	6.8%
343	Guillain-Barre Syndrome	6.8%
344	Epistaxis	6.8%
345	Striatonigral Degeneration	6.8%
346	Brain Diseases	6.7%
347	Dysautonomia	6.7%
348	Meningitis	6.7%
349	Movement Disorders	6.7%
350	Pachymeningitis	6.7%
351	Spinal Cord Diseases	6.7%
352	Vagus Nerve Disorder	6.7%
353	Glossopharyngeal Neuralgia	6.7%
354	Abducens Nerve Diseases	6.7%
355	Heavy Metal Poisoning, Nervous System	6.7%
356	Neuromuscular Junction Diseases	6.7%
357	Tauopathies	6.7%
358	Trochlear Nerve Diseases	6.7%
359	Peripheral Nervous System Diseases	6.7%
360	Myasthenia Gravis	6.7%
361	Dandy-Walker Syndrome	6.6%
362	Myelitis	6.6%
363	Progressive bulbar palsy	6.6%
364	Bulbar palsy	6.6%
365	Pneumocephalus	6.6%
366	Poliomyelitis	6.6%
367	Causalgia	6.5%
368	Bulimia	6.5%
369	Dysuria	6.5%
370	Fever of Unknown Origin	6.5%
371	Nocturia	6.5%
372	Snoring	6.5%
373	Prostatism	6.5%
374	Jaundice, Obstructive	6.5%
375	Leukoencephalitis, Acute Hemorrhagic	6.1%
376	Pleural Rub	6%
377	Rales	6%
378	Respiratory Sounds	6%
379	Rhonchi	6%
380	Stridor	6%
381	Wheezing	6%
382	Epidural Abscess	6%
383	Olfactory Nerve Injuries	6%
384	Neuroleptic Malignant Syndrome	6%
385	Myelinolysis, Central Pontine	6%
386	Livedo Reticularis	6%
387	Miller Fisher Syndrome	6%
388	Oliguria	5.9%
389	Polyuria	5.9%
390	Proteinuria	5.9%
391	Myelitis, Transverse	5.9%
392	MPTP Poisoning	5.9%
393	Chronic Fatigue Syndrome	5.8%
394	Lambert-Eaton Myasthenic Syndrome	5.8%
395	Underweight	5.8%
396	Overweight	5.8%
397	Shy-Drager Syndrome	5.8%
398	Sleep Disorders, Circadian Rhythm	5.8%
399	Reflex Sympathetic Dystrophy	5.7%
400	Subdural Effusion	5.7%
401	Parkinsonian Disorders	5.7%
402	Nocturnal Myoclonus Syndrome	5.7%
403	Encephalomyelitis, Acute Disseminated	5.7%
404	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	5.7%
405	Kearns-Sayre syndrome	5.7%
406	Shoulder Pain	5.7%
407	Angina, Unstable	5.7%
408	Ascites	5.6%
409	Calculi	5.6%
410	Fibrosis	5.6%
411	Gliosis	5.6%
412	Growth Disorders	5.6%
413	Hemorrhage	5.6%
414	Hernia	5.6%
415	Hyperbilirubinemia	5.6%
416	Hyperplasia	5.6%
417	Hypertrophy	5.6%
418	Hypomenorrhea	5.6%
419	Inflammation	5.6%
420	Intraoperative Complications	5.6%
421	Ischemia	5.6%
422	Lithiasis	5.6%
423	Malacoplakia	5.6%
424	Menstruation Disturbances	5.6%
425	Metaplasia	5.6%
426	Nails, Malformed	5.6%
427	Nerve Degeneration	5.6%
428	Ochronosis	5.6%
429	Polymenorrhea	5.6%
430	polyps	5.6%
431	Postoperative Complications	5.6%
432	Rupture, Spontaneous	5.6%
433	Sclerosis	5.6%
434	Shock	5.6%
435	Ulcer	5.6%
436	Enterocele	5.6%
437	Hyperammonemia	5.6%
438	Hyperamylasemia	5.6%
439	Teratogenesis	5.6%
440	Atheroma	5.6%
441	Cardiac Death	5.6%
442	Hypovolemia	5.6%
443	Hyperuricemia	5.6%
444	Leukoaraiosis	5.6%
445	Stenosis	5.6%
446	Facial asymmetry	5.6%
447	Dysbacteriosis	5.6%
448	Delayed Graft Function	5.6%
449	Cirrhosis	5.6%
450	Plaque, Amyloid	5.6%
451	Plaque, Atherosclerotic	5.6%
452	Neointima	5.6%
453	Dysbiosis	5.6%
454	Ataxia Telangiectasia	5.6%
455	Botulism	5.6%
456	Central Nervous System Cysts	5.6%
457	Neuromyelitis Optica	5.5%
458	Dystonia Musculorum Deformans	5.5%
459	Central Nervous System Infection	5.3%
460	Myopathy	5.3%
461	Optic Neuropathy	5.3%
462	Brain Injuries	5.3%
463	Brain Neoplasms	5.3%
464	Multiple Sclerosis	5.3%
465	Spinal Cord Neoplasms	5.3%
466	Hematemesis	5.2%
467	Purpura Fulminans	5.2%
468	Facial Nerve Injuries	5.2%
469	Facial Nerve Diseases	5.1%
470	Craniocerebral Trauma	5.1%
471	Parasomnia	5.1%
472	Dyssomnias	5.1%
473	Angina Pectoris, Variant	5.1%
474	Vestibulocochlear Nerve Diseases	5%
475	Hydranencephaly	5%
476	Neural Tube Defects	5%
477	Tethered Cord Syndrome	5%
478	Central Nervous System Neoplasms	5%
479	Iniencephaly	5%
480	Craniorachischisis	5%
481	Exencephaly	5%
482	Septo-Optic Dysplasia	5%
483	Cortical Dysplasia	5%
484	Malformations of Cortical Development	5%
485	Gagging	5%
486	Sweating, Gustatory	5%
487	Auriculotemporal Syndrome	5%
488	Morning Sickness	5%
489	Infarction	5%
490	Postoperative Hemorrhage	5%
491	Shock, Hemorrhagic	5%
492	Systemic Inflammatory Response Syndrome	5%
493	Incisional hernia	5%
494	Cri-du-Chat Syndrome	4.9%
495	Down Syndrome	4.9%
496	Trisomy 21	4.9%
497	Leukoencephalopathy, Progressive Multifocal	4.9%
498	Williams Syndrome	4.9%
499	Meige Syndrome	4.9%
500	Brachial Plexus Neuritis	4.9%
501	Neuralgic Amyotrophy	4.9%
502	Cerebral Ventriculitis	4.9%
503	Emaciation	4.9%
504	Epilepsy, Post-Traumatic	4.9%
505	Rett Syndrome	4.9%
506	Weight Gain	4.8%
507	Limbic Encephalitis	4.7%
508	Scrapie	4.7%
509	Central Cord Syndrome	4.7%
510	Presenile dementia	4.6%
511	Senile dementia	4.6%
512	Meningocele	4.6%
513	Meningitis, Bacterial	4.6%
514	Meningitis, Fungal	4.6%
515	Encephalocele	4.6%
516	Acrodynia	4.6%
517	Huntington Disease	4.6%
518	Myasthenia Gravis, Autoimmune, Experimental	4.5%
519	Lafora Disease	4.5%
520	Unverricht-Lundborg Syndrome	4.5%
521	Tarsal Tunnel Syndrome	4.5%
522	Cauda Equina Syndrome	4.5%
523	Posterior Leukoencephalopathy Syndrome	4.5%
524	Posterior reversible encephalopathy syndrome	4.5%
525	Brain Abscess	4.4%
526	Cyst	4.4%
527	Extravasation of Diagnostic and Therapeutic Materials	4.4%
528	Neoplastic Processes	4.4%
529	Charcot-Marie-Tooth Disease	4.4%
530	Akinetic Mutism	4.4%
531	Anoxic Encephalopathy	4.4%
532	Arachnoiditis	4.4%
533	Basal Ganglia Diseases	4.4%
534	Brain Damage, Chronic	4.4%
535	Cerebellar Diseases	4.4%
536	Encephalitis	4.4%
537	Encephalomalacia	4.4%
538	Epilepsy	4.4%
539	Hydrocephalus	4.4%
540	Congenital Hydrocephalus	4.4%
541	Hypothalamic Diseases	4.4%
542	Aseptic Meningitis	4.4%
543	Neuritis	4.4%
544	Polyneuritis	4.4%
545	Radiculitis	4.4%
546	Syringomyelia	4.4%
547	Thalamic Diseases	4.4%
548	Intracranial Hypertension	4.4%
549	Polyneuropathy	4.4%
550	Mononeuritis	4.4%
551	Aura	4.4%
552	Leukoencephalopathy	4.4%
553	Essential Tremor	4.4%
554	Neuroaxonal Dystrophies	4.4%
555	Familial Tremor	4.4%
556	Headache Disorders	4.4%
557	Mononeuropathies	4.4%
558	Intracranial Hypotension	4.4%
559	Brachial Plexus Neuropathies	4.4%
560	Radiculopathy	4.4%
561	Mononeuropathy Multiplex	4.4%
562	Nerve Root Compression	4.4%
563	Brain Edema	4.4%
564	Brain Hypoxia	4.4%
565	Aqueductal Stenosis	4.4%
566	Pneumorrhachis	4.4%
567	Writer's Cramp	4.4%
568	Lupus Vasculitis, Central Nervous System	4.4%
569	Vasculitis, Central Nervous System	4.3%
570	Cerebellar Neoplasms	4.3%
571	Leukoplakia	4.3%
572	Necrosis	4.3%
573	Granulomatosis, Orofacial	4.3%
574	Pigmentation Disorders	4.3%
575	Respiratory Aspiration	4.3%
576	Airway Remodeling	4.3%
577	Prader-Willi Syndrome	4.2%
578	Acantholysis	4.2%
579	Chromosome Aberrations	4.2%
580	Dehydration	4.2%
581	Granuloma	4.2%
582	Leukocytosis	4.2%
583	Pleocytosis	4.2%
584	Ventricular Remodeling	4.2%
585	Alopecia	4.2%
586	Androgenetic Alopecia	4.2%
587	Birth Weight	4.1%
588	Canavan Disease	4.1%
589	Alexander Disease	4.1%
590	Paraneoplastic Encephalomyelitis	4.1%
591	Cachexia	4%
592	Dementia, Vascular	4%
593	Myoclonic Epilepsy	4%
594	Epilepsy, Temporal Lobe	4%
595	Epilepsy, Rolandic	4%
596	Benign Rolandic Epilepsy	4%
597	Brain Hemorrhage, Traumatic	4%
598	Uveomeningoencephalitic Syndrome	4%
599	Sturge-Weber Syndrome	4%
600	Fetal Hypoxia	4%
601	Alcohol-Induced Disorders, Nervous System	4%
602	Tuberous Sclerosis	4%
603	Dyspnea, Paroxysmal	3.9%
604	Friedreich Ataxia	3.9%
605	Creutzfeldt-Jakob disease	3.9%
606	Urinary Incontinence	3.9%
607	Basal Ganglia Cerebrovascular Disease	3.9%
608	Brain Injuries, Diffuse	3.9%
609	Traumatic Brain Injury	3.9%
610	Albuminuria	3.9%
611	Hemoglobinuria	3.9%
612	Supratentorial Neoplasms	3.9%
613	Multiple Sclerosis, Chronic Progressive	3.9%
614	Multiple Sclerosis, Relapsing-Remitting	3.9%
615	Myotonia Congenita	3.8%
616	Paraneoplastic Cerebellar Degeneration	3.8%
617	Thrombocytopenic purpura	3.8%
618	Neuritis, Autoimmune, Experimental	3.8%
619	Waterhouse-Friderichsen Syndrome	3.7%
620	Hematoma, Subdural	3.7%
621	Hematoma, Epidural, Cranial	3.7%
622	Purpura, Hyperglobulinemic	3.7%
623	Hyperemesis Gravidarum	3.7%
624	Tuberculosis, Meningeal	3.7%
625	Carotid Artery Injuries	3.7%
626	Juvenile Myoclonic Epilepsy	3.6%
627	Myoclonic Epilepsies, Progressive	3.6%
628	Carpal Tunnel Syndrome	3.6%
629	Vascular Headaches	3.6%
630	neurofibroma	3.6%
631	Hypoxia-Ischemia, Brain	3.6%
632	Basal Ganglia Hemorrhage	3.5%
633	Genomic Instability	3.5%
634	Fragile X Syndrome	3.5%
635	Myotonic Dystrophy	3.5%
636	Hepatolenticular Degeneration	3.4%
637	Brain Diseases, Metabolic	3.4%
638	Cerebrovascular Disorders	3.4%
639	Myositis	3.4%
640	Optic Atrophy	3.4%
641	Optic Neuritis	3.4%
642	Papilledema	3.4%
643	Strabismus	3.4%
644	Tolosa-Hunt Syndrome	3.4%
645	Cerebrovascular Insufficiency	3.4%
646	Isaacs syndrome	3.4%
647	Arsenic Poisoning	3.4%
648	Dementia	3.4%
649	Myotonic Disorders	3.4%
650	Central Nervous System Fungal Infections	3.4%
651	Conus Medullaris Syndrome	3.4%
652	Myasthenic Syndromes, Congenital	3.4%
653	Spinal Cord Vascular Diseases	3.4%
654	Adrenoleukodystrophy	3.4%
655	Smith-Magenis syndrome	3.4%
656	Dural Arteriovenous Fistula	3.3%
657	Chromosomal Instability	3.3%
658	Diverticulum	3.3%
659	Diverticulosis	3.3%
660	Diabetic Neuropathies	3.3%
661	Facial Injuries	3.3%
662	Facial Neuralgia	3.3%
663	Diabetic Amyotrophy	3.3%
664	Diabetic Autonomic Neuropathy	3.3%
665	Sleep Talking	3.3%
666	Manganese Poisoning	3.3%
667	Sleep Disorders, Intrinsic	3.3%
668	Azotemia	3.3%
669	Acute Disease	3.3%
670	Acute-Phase Reaction	3.3%
671	Amenorrhea	3.3%
672	Chronic disease	3.3%
673	Critical Illness	3.3%
674	Sudden death	3.3%
675	Fat necrosis	3.3%
676	Gangrene	3.3%
677	Graft Occlusion, Vascular	3.3%
678	Granuloma, Plasma Cell	3.3%
679	Hematoma	3.3%
680	Diaphragmatic Hernia	3.3%
681	Hydrops Fetalis	3.3%
682	Iatrogenic Disease	3.3%
683	Intestinal Polyps	3.3%
684	Multiple Organ Failure	3.3%
685	Oligomenorrhea	3.3%
686	Premenstrual syndrome	3.3%
687	Recurrence	3.3%
688	Retrograde Degeneration	3.3%
689	Retroperitoneal fibrosis	3.3%
690	Serositis	3.3%
691	Splenomegaly	3.3%
692	Subcutaneous Emphysema	3.3%
693	Surgical Wound Dehiscence	3.3%
694	Syndrome	3.3%
695	Wallerian Degeneration	3.3%
696	Pyogenic granuloma	3.3%
697	Exsanguination	3.3%
698	Disease Progression	3.3%
699	Seroma	3.3%
700	Premenstrual Tension	3.3%
701	Delayed Emergence from Anesthesia	3.3%
702	Infant Death	3.3%
703	Anastomotic Leak	3.3%
704	Intraoperative Awareness	3.3%
705	Rubinstein-Taybi Syndrome	3.3%
706	Leukomalacia, Periventricular	3.3%
707	Meningeal Neoplasms	3.3%
708	Meningomyelocele	3.3%
709	Spina Bifida	3.3%
710	Mercury Poisoning, Nervous System	3.3%
711	Lead Poisoning, Nervous System	3.3%
712	Vestibular Neuronitis	3.3%
713	Cerebral Palsy	3.3%
714	Epilepsies, Partial	3.3%
715	Epilepsy, Generalized	3.3%
716	Pseudotumor Cerebri	3.3%
717	Sciatic Neuropathy	3.3%
718	Hypertensive Encephalopathy	3.3%
719	Ulnar Neuropathies	3.3%
720	Lesion of Sciatic Nerve	3.3%
721	Simple Partial Seizures	3.3%
722	Epilepsy, Reflex	3.3%
723	Ulnar Neuritis	3.3%
724	Radial nerve compression	3.3%
725	Radial Tunnel Syndrome	3.3%
726	Peroneal Neuropathies	3.3%
727	Radial Neuropathy	3.3%
728	Median Neuropathy	3.3%
729	Sciatic Nerve Palsy	3.3%
730	Femoral Neuropathy	3.3%
731	Tibial Neuropathy	3.3%
732	Ulnar Nerve Palsy	3.3%
733	Postural Orthostatic Tachycardia Syndrome	3.3%
734	Radial nerve palsy	3.3%
735	Headache Disorders, Primary	3.3%
736	Headache Disorders, Secondary	3.3%
737	Medication overuse headache	3.3%
738	Menorrhagia	3.3%
739	Sudden infant death syndrome	3.3%
740	Fetal Weight	3.3%
741	Brain Concussion	3.2%
742	Obesity	3.2%
743	Cubital Tunnel Syndrome	3.2%
744	Diffuse Axonal Injury	3.2%
745	Brain Stem Neoplasms	3.2%
746	Putaminal Hemorrhage	3.1%
747	Pituitary Adenoma	3.1%
748	Pituitary Neoplasms	3.1%
749	Optic Nerve Glioma	3.1%
750	Toxoplasmosis, Cerebral	3.1%
751	Hematoma, Subdural, Intracranial	3%
752	Hematoma, Subdural, Chronic	3%
753	Hematoma, Subdural, Acute	3%
754	Vertebral Artery Dissection	3%
755	Refsum Disease	3%
756	Meningitis, Cryptococcal	3%
757	Meningitis, Listeria	3%
758	Meningitis, Haemophilus	3%
759	Meningitis, Pneumococcal	3%
760	Frontotemporal dementia	3%
761	Subarachnoid Hemorrhage	2.9%
762	Cerebral Hemorrhage	2.9%
763	Urge Incontinence	2.9%
764	Choroid Plexus Papilloma	2.9%
765	Cardiotoxicity	2.8%
766	Alstrom Syndrome	2.8%
767	Mitochondrial Encephalomyopathies	2.8%
768	Hand-Arm Vibration Syndrome	2.8%
769	Tinea Pedis	2.8%
770	Purpura, Thrombotic Thrombocytopenic	2.8%
771	Pituitary Apoplexy	2.7%
772	Fibromyalgia	2.7%
773	Optic Neuropathy, Ischemic	2.7%
774	Anterior Ischemic Optic Neuropathy	2.7%
775	Central Nervous System Bacterial Infections	2.7%
776	Medial Tibial Stress Syndrome	2.7%
777	Polyradiculopathy	2.7%
778	Post-Traumatic Headache	2.7%
779	Tension Headache	2.7%
780	Epilepsy, Complex Partial	2.7%
781	Migraine Disorders	2.7%
782	Abdominal Migraine	2.7%
783	Status Migrainosus	2.7%
784	Cervicogenic Headache	2.7%
785	Menkes Kinky Hair Syndrome	2.7%
786	Brain Contusion	2.7%
787	Brain Infarction	2.7%
788	Facial Hemiatrophy	2.7%
789	Melkersson-Rosenthal Syndrome	2.7%
790	Mitochondrial Myopathies	2.7%
791	Subarachnoid Hemorrhage, Traumatic	2.7%
792	Carotid Artery, Internal, Dissection	2.7%
793	Eosinophilia-Myalgia Syndrome	2.7%
794	Subacute Sclerosing Panencephalitis	2.7%
795	Sleep Bruxism	2.6%
796	Anencephaly	2.6%
797	Asphyxia	2.6%
798	Granuloma, Respiratory Tract	2.6%
799	Shock, Traumatic	2.6%
800	Respiratory Tract Fistula	2.6%
801	Pituitary Diseases	2.6%
802	Infarction, Middle Cerebral Artery	2.6%
803	Infarction, Anterior Cerebral Artery	2.6%
804	Infarction, Posterior Cerebral Artery	2.6%
805	Amyloid Neuropathies, Familial	2.5%
806	Classical Lissencephalies and Subcortical Band Heterotopias	2.5%
807	Disease susceptibility	2.5%
808	Fetal Death	2.5%
809	Foreign-Body Reaction	2.5%
810	Gastrointestinal Hemorrhage	2.5%
811	Cardiomegaly	2.5%
812	Hemarthrosis	2.5%
813	Hemoperitoneum	2.5%
814	Hemothorax	2.5%
815	Hepatomegaly	2.5%
816	Neoplasm Invasiveness	2.5%
817	Neoplasm Metastasis	2.5%
818	Neoplasm Recurrence, Local	2.5%
819	Parovarian Cyst	2.5%
820	Postpericardiotomy Syndrome	2.5%
821	Prosthesis Failure	2.5%
822	Reperfusion Injury	2.5%
823	Spermatocele	2.5%
824	Oral Fistula	2.5%
825	Injection Site Reaction	2.5%
826	Retrobulbar Hemorrhage	2.5%
827	Cutaneous Fistula	2.5%
828	Aseptic Necrosis of Bone	2.5%
829	Peritoneal Fibrosis	2.5%
830	Carcinogenesis	2.5%
831	Perinatal death	2.5%
832	Infusion site reaction	2.5%
833	Cardiac Hypertrophy	2.5%
834	Nephrogenic Fibrosing Dermopathy	2.5%
835	Corneal Endothelial Cell Loss	2.5%
836	Encapsulating Peritoneal Sclerosis	2.5%
837	Vasoplegia	2.5%
838	Suppuration	2.5%
839	Nephrogenic Systemic Fibrosis	2.5%
840	Metastasis	2.5%
841	Kernicterus	2.5%
842	Thoracic Outlet Syndrome	2.5%
843	Sinus Arrhythmia	2.5%
844	Atrial Fibrillation	2.5%
845	Atrial Flutter	2.5%
846	Dental Pulp Necrosis	2.5%
847	Granuloma, Foreign-Body	2.5%
848	Mediastinal Emphysema	2.5%
849	Surgical Wound Infection	2.5%
850	Ventricular Fibrillation	2.5%
851	Ventricular Flutter	2.5%
852	Parasystole	2.5%
853	Paroxysmal atrial fibrillation	2.5%
854	Facies	2.5%
855	Bradycardia	2.5%
856	Embryo Loss	2.5%
857	Afferent Loop Syndrome	2.5%
858	Carotid Artery Diseases	2.5%
859	Brain Ischemia	2.5%
860	Esotropia	2.5%
861	Exotropia	2.5%
862	Hypotension, Orthostatic	2.5%
863	Sex Chromosome Aberrations	2.5%
864	Short Bowel Syndrome	2.5%
865	Sleep Apnea Syndromes	2.5%
866	Cerebrovascular accident	2.5%
867	Uterine hemorrhage	2.5%
868	Vaginal Fistula	2.5%
869	Polymyositis	2.5%
870	Rectocele	2.5%
871	No-Reflow Phenomenon	2.5%
872	Kluver-Bucy Syndrome	2.5%
873	Vasospasm, Intracranial	2.5%
874	Spinal Cord Ischemia	2.5%
875	Intracranial Arterial Diseases	2.5%
876	Post-Exercise Hypotension	2.5%
877	Disorders of Excessive Somnolence	2.4%
878	Sleep Initiation and Maintenance Disorders	2.4%
879	Night Terrors	2.4%
880	Somnambulism	2.4%
881	Trigeminal Nerve Disorder	2.4%
882	Transient Insomnia	2.4%
883	Sleep Paralysis	2.4%
884	Chronic Insomnia	2.4%
885	REM Sleep Behavior Disorder	2.4%
886	Hypersomnia	2.4%
887	Dermal Sinus	2.4%
888	Spina Bifida Cystica	2.4%
889	Spina Bifida Occulta	2.4%
890	Meningeal Carcinomatosis	2.4%
891	Lissencephaly	2.4%
892	Polymicrogyria	2.4%
893	Pachygyria	2.4%
894	Schizencephaly	2.4%
895	Lead Poisoning, Nervous System, Childhood	2.4%
896	Lead Poisoning, Nervous System, Adult	2.4%
897	Periventricular Nodular Heterotopia	2.4%
898	Cluster Headache	2.4%
899	Migraine with Aura	2.4%
900	Familial Hemiplegic Migraine	2.4%
901	Chronic Paroxysmal Hemicrania	2.4%
902	SUNCT Syndrome	2.4%
903	Paroxysmal Hemicrania	2.4%
904	Tuberculosis, Central Nervous System	2.4%
905	Mucopolysaccharidosis II	2.4%
906	Pediatric Obesity	2.4%
907	Cerebral Infarction	2.4%
908	Brain Stem Infarctions	2.4%
909	Acoustic Neuroma	2.4%
910	Giant Cell Arteritis	2.4%
911	Temporal Arteritis	2.4%
912	Endotoxic shock	2.3%
913	Septic Shock	2.3%
914	Toxic Shock Syndrome	2.3%
915	Duane Retraction Syndrome	2.3%
916	Lateral Medullary Syndrome	2.3%
917	Mobius Syndrome	2.2%
918	Bell Palsy	2.2%
919	Herpes Zoster Oticus	2.2%
920	Familial Periodic Paralysis	2.2%
921	Autoimmune thrombocytopenia	2.2%
922	Immune thrombocytopenic purpura	2.2%
923	MELAS Syndrome	2.2%
924	Moyamoya Disease	2.2%
925	Tissue Adhesions	2.2%
926	Colonic Polyps	2.2%
927	Hematoma, Epidural, Spinal	2.2%
928	Neurofibrosarcoma	2.2%
929	Chromosome Fragility	2.2%
930	West Nile Fever	2.1%
931	Empty Sella Syndrome	2.1%
932	Hyperpituitarism	2.1%
933	Hypopituitarism	2.1%
934	Hypophysitis	2.1%
935	Drowning	2.1%
936	Eye Injuries	2%
937	Nasal Polyps	2%
938	Cerebral Arterial Diseases	2%
939	Vertebrobasilar Insufficiency	2%
940	Anterior Spinal Artery Syndrome	2%
941	Basilar Artery Stenosis	2%
942	Vertebral Artery Stenosis	2%
943	Sleep Apnea, Obstructive	2%
944	Sleep Apnea, Central	2%
945	Intracranial Hemorrhage, Hypertensive	2%
946	Transient Cerebral Ischemia	2%
947	Narcolepsy	2%
948	Trigeminal Neuralgia	2%
949	Kleine-Levin Syndrome	2%
950	Fetal Growth Retardation	2%
951	DNA Degradation, Necrotic	2%
952	Aneuploidy	2%
953	Muscular Dystrophy	2%
954	Polyploidy	2%
955	Congenital nystagmus	2%
956	Microsatellite Instability	2%
957	Orbital Myositis	2%
958	Optic Atrophy, Hereditary, Leber	2%
959	Heart Block	2%
960	Tachycardia	2%
961	Tachyarrhythmia	2%
962	Cicatrix	2%
963	Hematuria	2%
964	Reye Syndrome	2%
965	Urinary Calculi	2%
966	Granuloma Annulare	2%
967	Chromosome Breakage	2%
968	Neuroaspergillosis	2%
969	Pyomyositis	2%
970	Intracranial Embolism and Thrombosis	2%
971	Hepatic Encephalopathy	2%
972	Shock, Cardiogenic	2%
973	Neuronal Ceroid-Lipofuscinoses	1.9%
974	Sick Sinus Syndrome	1.9%
975	Trisomy	1.9%
976	Hyperprolactinemia	1.8%
977	Subclavian Steal Syndrome	1.8%
978	Pick Disease of the Brain	1.8%
979	Cataplexy	1.8%
980	Pseudorabies	1.7%
981	Giant Cell Epulis	1.7%
982	Aicardi's syndrome	1.7%
983	Biliary Fistula	1.7%
984	Cross Infection	1.7%
985	Gastric Fistula	1.7%
986	Hyphema	1.7%
987	Retinal Neovascularization	1.7%
988	Septicemia	1.7%
989	Vitreous Hemorrhage	1.7%
990	Congenital diaphragmatic hernia	1.7%
991	Sepsis	1.7%
992	Cockayne Syndrome	1.7%
993	Toxoplasmosis, Congenital	1.7%
994	Leukoplakia, Oral	1.6%
995	Long QT Syndrome	1.6%
996	Brain Diseases, Metabolic, Inborn	1.6%
997	Eye Burns	1.6%
998	Alcohol Withdrawal Delirium	1.6%
999	Abscess	1.6%
1000	Dental Fistula	1.6%
1001	Empyema	1.6%
1002	Femur Head Necrosis	1.6%
1003	Fetal Resorption	1.6%
1004	Lymphatic Metastasis	1.6%
1005	Malaria, Cerebral	1.6%
1006	Neoplasms, Unknown Primary	1.6%
1007	Oroantral Fistula	1.6%
1008	Peptic Ulcer Hemorrhage	1.6%
1009	Sudden Cardiac Death	1.6%
1010	POEMS Syndrome	1.6%
1011	Left Ventricular Hypertrophy	1.6%
1012	Leukemic Infiltration	1.6%
1013	Right Ventricular Hypertrophy	1.6%
1014	Premenstrual Dysphoric Disorder	1.6%
1015	Choroidal Neovascularization	1.6%
1016	Primary Graft Dysfunction	1.6%
1017	Neoplasm Micrometastasis	1.6%
1018	Meningioma	1.6%
1019	Carotid Stenosis	1.6%
1020	Intracranial Aneurysm	1.6%
1021	Welander Distal Myopathy	1.6%
1022	Dumping Syndrome	1.6%
1023	Microcephaly	1.6%
1024	Rectal Prolapse	1.6%
1025	Uterine Prolapse	1.6%
1026	Cicatrix, Hypertrophic	1.6%
1027	Vaginal Prolapse	1.6%
1028	Macrocephaly	1.6%
1029	Sinus Arrest, Cardiac	1.6%
1030	Neurocysticercosis	1.6%
1031	Micronuclei, Chromosome-Defective	1.6%
1032	Neurosyphilis	1.6%
1033	Hypokalemic periodic paralysis	1.6%
1034	Hematoma, Subdural, Spinal	1.6%
1035	Metrorrhagia	1.6%
1036	Intracranial Arteriosclerosis	1.6%
1037	Cerebral Atherosclerosis	1.6%
1038	Cerebral Arteriosclerosis	1.6%
1039	Cerebral Thrombosis	1.6%
1040	Intracranial Embolism	1.6%
1041	Intracranial Thrombosis	1.6%
1042	Porencephaly	1.6%
1043	Vesicovaginal Fistula	1.6%
1044	Acromegaly	1.5%
1045	Holoprosencephaly	1.5%
1046	Cerebral Amyloid Angiopathy	1.4%
1047	Sinus Thrombosis, Intracranial	1.4%
1048	Eosinophilic Granuloma	1.4%
1049	Wernicke Encephalopathy	1.4%
1050	AIDS Dementia Complex	1.4%
1051	Dermatomyositis	1.4%
1052	Corneal Scar	1.4%
1053	Lyme Neuroborreliosis	1.4%
1054	Muscular Dystrophy, Duchenne	1.4%
1055	Cavernous Sinus Thrombosis	1.4%
1056	Sagittal Sinus Thrombosis	1.4%
1057	Bronchial Fistula	1.4%
1058	Pancreatic Fistula	1.4%
1059	Retinal Hemorrhage	1.4%
1060	Carotid Artery Thrombosis	1.3%
1061	Choroid Hemorrhage	1.3%
1062	Intestinal Fistula	1.3%
1063	Melena	1.3%
1064	Gastroschisis	1.3%
1065	Enterocutaneous Fistula	1.3%
1066	Postpartum Hemorrhage	1.3%
1067	Salivary Gland Fistula	1.3%
1068	Cystocele	1.3%
1069	Gingival Hemorrhage	1.3%
1070	Keloid	1.3%
1071	Monosomy	1.3%
1072	Tetraploidy	1.3%
1073	Stillbirth	1.3%
1074	Adams-Stokes Syndrome	1.3%
1075	Atrioventricular Block	1.3%
1076	Bundle-Branch Block	1.3%
1077	Atrial Premature Complexes	1.3%
1078	Sinoatrial Block	1.3%
1079	Tachycardia, Paroxysmal	1.3%
1080	Supraventricular tachycardia	1.3%
1081	Tachycardia, Ventricular	1.3%
1082	Tachycardia, Reciprocating	1.3%
1083	Viremia	1.3%
1084	Parasitemia	1.3%
1085	Umbilical hernia	1.2%
1086	Corneal Perforation	1.2%
1087	Nelson Syndrome	1.1%
1088	Cellulitis	1.1%
1089	Romano-Ward Syndrome	1.1%
1090	Fabry Disease	1.1%
1091	Prolactinoma	1%
1092	Growth Hormone-Secreting Pituitary Adenoma	1%
1093	Galactosemias	1%
1094	Urea Cycle Disorders, Inborn	1%
1095	Tyrosinemias	1%
1096	Bacteremia	1%
1097	Cell Transformation, Viral	1%
1098	Fungemia	1%
1099	Granuloma, Laryngeal	1%
1100	Tachycardia, Atrioventricular Nodal Reentry	1%
1101	Tachycardia, Ectopic Atrial	1%
1102	Tachycardia, Ectopic Junctional	1%
1103	Sinus Tachycardia	1%
1104	Torsades de Pointes	1%
1105	Accelerated Idioventricular Rhythm	1%
1106	Myocardial Reperfusion Injury	0.9%
1107	Urinary Bladder Fistula	0.9%
1108	Homocystinuria	0.9%
1109	Leigh Disease	0.9%
1110	Arteriovenous fistula	0.8%
1111	Rectal Fistula	0.8%
1112	Anal Fistula	0.8%
1113	Endotoxemia	0.8%
1114	Carbamoyl-Phosphate Synthase I Deficiency Disease	0.8%
1115	Philadelphia Chromosome	0.8%
1116	Glycogen storage disease type II	0.7%
1117	Kidney Calculi	0.7%
1118	Ureteral Calculi	0.7%
1119	Zellweger Syndrome	0.7%
1120	Gaucher Disease	0.6%
1121	Tay-Sachs Disease	0.6%
1122	Candidemia	0.6%
1123	Niemann-Pick Disease, Type C	0.5%

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