MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

(UMLS:C1292772)

UMLS ID:: C1292772
MeSH ID:: D054438

Classification 1:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.337.539.300

Classification 2:

Name:

Hemic and Lymphatic Diseases
MeSH Tree Number(s):: C15.378.190.615.500

Synonym(s)

Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

Atypical CML

Atypical Chronic Myeloid Leukemia

Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative

Atypical chronic myeloid leukaemia

Atypical chronic myeloid leukemia

Atypical chronic myeloid leukemia, BCR/ABL negative

Atypical chronic myeloid leukemia, Philadelphia chromosome (Ph1) negative

Philadelphia-Negative Myelogenous Leukemia

10.

Subacute Myeloid Leukemia

11.

Subacute granulocytic leukaemia

12.

Subacute granulocytic leukemia

13.

Subacute myelogenous leukaemia

14.

Subacute myelogenous leukemia

15.

Subacute myeloid leukaemia

16.

Subacute myeloid leukemia

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Busulfan		1349249	CTD
2	Cyclophosphamide		1349249	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Leukemia, Myelomonocytic, Chronic	48.4%
2	Sarcoma, Myeloid	29%
3	Leukemia, Myeloid, Chronic-Phase	26.4%
4	MYELODYSPLASTIC SYNDROME	22.8%
5	Bone Marrow Neoplasms	21.7%
6	Polycythemia Vera	19.4%
7	Thrombocythemia, Essential	18.7%
8	Thrombocytosis	18.7%
9	Disseminated Intravascular Coagulation	17.8%
10	Protein S Deficiency	17.8%
11	Leukemia, Plasma Cell	17.5%
12	Leukemia, Experimental	17.2%
13	Hematologic Neoplasms	16.9%
14	Anemia	16.7%
15	Blood Coagulation Disorders	16.7%
16	Blood Platelet Disorders	16.7%
17	Hemorrhagic Disorders	16.7%
18	Leukocyte Disorders	16.7%
19	Methemoglobinemia	16.7%
20	Neoplasms, Germ Cell and Embryonal	16.7%
21	Neoplasms, Glandular and Epithelial	16.7%
22	Pancytopenia	16.7%
23	Polycythemia	16.7%
24	Sulfhemoglobinemia	16.7%
25	Thrombophilia	16.7%
26	Germ Cell Cancer	16.7%
27	Erythrocytosis	16.7%
28	Hemoglobinuria, Paroxysmal	16.1%
29	Leukemoid Reaction	16.1%
30	Primary Myelofibrosis	15.1%
31	Myelofibrosis	15.1%
32	Myeloid Metaplasia	15.1%
33	bone marrow fibrosis	15.1%
34	Histiocytic Disorders, Malignant	15%
35	Neuroectodermal Tumors	14.8%
36	Leukemia, Radiation-Induced	14.5%
37	Leukemia L1210	13.8%
38	Leukemia P388	13.8%
39	Neoplasms, Neuroepithelial	13.6%
40	Gliomatosis cerebri	13.6%
41	Transfusion Reaction	13.2%
42	Hypotensive Transfusion Reaction	13.2%
43	Thrombasthenia	13.1%
44	Antithrombin III Deficiency	13.1%
45	Protein C Deficiency	13.1%
46	Pregnancy Complications, Hematologic	12.7%
47	Carcinosarcoma	12.2%
48	Hemangiosarcoma	12.2%
49	lymphangiosarcoma	12.2%
50	Lymphoma	12%
51	Vitamin K Deficiency	11.7%
52	melanoma	11.6%
53	Afibrinogenemia	11.4%
54	Factor VII Deficiency	11.4%
55	Factor X Deficiency	11.4%
56	Factor XII Deficiency	11.4%
57	Hemophilia A	11.4%
58	Activated Protein C Resistance	11.4%
59	Factor II deficiency	11.4%
60	Factor VIII Deficiency	11.4%
61	Factor V deficiency	11.4%
62	Factor XI Deficiency	11.4%
63	Hypoprothrombinemias	11.4%
64	Anemia, Diamond-Blackfan	11.3%
65	Composite Lymphoma	10.9%
66	Meningioma	10.6%
67	Hamartoma	10.5%
68	Lymphatic Diseases	10.5%
69	Neoplasms, Hormone-Dependent	10.5%
70	Neoplasms, Multiple Primary	10.5%
71	Paraneoplastic Syndromes	10.5%
72	Precancerous Conditions	10.5%
73	Neoplasms, Second Primary	10.5%
74	Leukemia, T-Cell	10.3%
75	Leukemia, B-Cell	10.3%
76	Carcinoma 256, Walker	10.2%
77	Waldenstrom Macroglobulinemia	9.8%
78	Adenoma	9.8%
79	Ameloblastoma	9.8%
80	Anemia, Hemolytic	9.8%
81	Anemia, Macrocytic	9.8%
82	Angiokeratoma	9.8%
83	Carcinoma	9.8%
84	Chordoma	9.8%
85	Eosinophilia	9.8%
86	Hemangioma	9.8%
87	hemangiopericytoma	9.8%
88	Hypoproteinemia	9.8%
89	Leukopenia	9.8%
90	Lymphangioma	9.8%
91	Mesenchymoma	9.8%
92	Nevus	9.8%
93	Teratoma	9.8%
94	Thrombocytopenia	9.8%
95	Hepatoblastoma	9.8%
96	Mixed Tumor, Mullerian	9.8%
97	Germinoma	9.8%
98	Teratocarcinoma	9.8%
99	Angiofibroma	9.8%
100	Leukostasis	9.8%
101	Sarcoma	9.8%
102	Epithelioma	9.8%
103	Basal cell carcinoma	9.7%
104	Carcinoma, Papillary	9.7%
105	Squamous cell carcinoma	9.7%
106	Chondrosarcoma	9.7%
107	Craniopharyngioma	9.7%
108	Cystadenoma	9.7%
109	leiomyosarcoma	9.7%
110	liposarcoma	9.7%
111	Mesothelioma	9.7%
112	synovial sarcoma	9.7%
113	Neuroectodermal Tumor, Melanotic	9.7%
114	Angiomyolipoma	9.7%
115	Clear Cell Sarcoma of Soft Tissue	9.7%
116	Alveolar Soft Part Sarcoma	9.7%
117	Neuroendocrine Tumors	9.7%
118	Carcinoma, Basal Cell	9.7%
119	Adenoma, Acidophil	9.6%
120	Ganglioneuroma	9.6%
121	Glioma	9.6%
122	Malignant Glioma	9.6%
123	Medulloblastoma	9.5%
124	Trophoblastic Neoplasms	9.3%
125	Thymoma	9.2%
126	Carcinoma, Ehrlich Tumor	9.1%
127	Dermoid Cyst	9.1%
128	Carcinoma, Lewis Lung	9.1%
129	Malignant histiocytosis	8.9%
130	Histiocytic sarcoma	8.9%
131	Carcinoid Tumor	8.6%
132	Neurilemmoma	8.6%
133	Hutchinson's Melanotic Freckle	8.6%
134	Melanoma, Amelanotic	8.6%
135	Multiple Myeloma	8.6%
136	Melanoma, Experimental	8.6%
137	Lymphocele	8.5%
138	Cystadenocarcinoma	8.4%
139	Fibrosarcoma	8.4%
140	Osteosarcoma	8.4%
141	Mucoepidermoid Carcinoma	8.4%
142	Fanconi Anemia	8.1%
143	Agammaglobulinemia	8%
144	Wiskott-Aldrich Syndrome	8%
145	Purpura, Thrombotic Thrombocytopenic	7.9%
146	Cyst	7.9%
147	Neoplastic Processes	7.9%
148	Neoplastic Syndromes, Hereditary	7.9%
149	Pregnancy Complications, Neoplastic	7.9%
150	Adenofibroma	7.8%
151	Fibroadenoma	7.8%
152	Malignant Fibrous Histiocytoma	7.8%
153	Hemangioma, Cavernous	7.8%
154	Neoplasms, Experimental	7.8%
155	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	7.7%
156	Leukemia, Large Granular Lymphocytic	7.7%
157	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	7.7%
158	Astrocytoma	7.6%
159	Ependymoma	7.6%
160	oligodendroglioma	7.6%
161	Ganglioglioma	7.6%
162	gliosarcoma	7.6%
163	Anaplastic astrocytoma	7.6%
164	Anaplastic Oligodendroglioma	7.6%
165	Lymphangioleiomyomatosis	7.5%
166	Anemia, Neonatal	7.5%
167	Leukocytosis	7.5%
168	Paraproteinemias	7.5%
169	Pelger-Huet Anomaly	7.5%
170	Pleocytosis	7.5%
171	Plasmacytoma	7.4%
172	Anemia, Sickle Cell	7.4%
173	Thalassemia	7.4%
174	Acanthoma	7.3%
175	Choriocarcinoma	7.3%
176	Carcinoma, Lobular	7.3%
177	Sarcoma, Experimental	7.2%
178	Endometrial Stromal Sarcoma	7.2%
179	Bowen's Disease	7.2%
180	Paraganglioma	7.2%
181	Rhabdomyosarcoma	7.2%
182	Giant Cell Tumor of Bone	7.2%
183	Malignant Carcinoid Syndrome	7.2%
184	Hodgkin Disease	7.1%
185	Lymphoma, Non-Hodgkin	7.1%
186	Glioblastoma	6.7%
187	Neuroblastoma	6.7%
188	Splenic Neoplasms	6.7%
189	Glioblastoma Multiforme	6.7%
190	Thymus Neoplasms	6.7%
191	Dermatofibrosarcoma	6.6%
192	Dermatofibrosarcoma Protuberans	6.6%
193	Infectious Mononucleosis	6.6%
194	Cryoglobulinemia	6.5%
195	Monoclonal Gammopathy of Undetermined Significance	6.5%
196	Adenocarcinoma	6.5%
197	Agranulocytosis	6.5%
198	Anemia, Megaloblastic	6.5%
199	Carcinoma in Situ	6.5%
200	Carcinoma, Transitional Cell	6.5%
201	Phyllodes Tumor	6.5%
202	Dysgerminoma	6.5%
203	Hemangioendothelioma	6.5%
204	Lipoma	6.5%
205	Lymphocytosis	6.5%
206	Myoma	6.5%
207	Myxoma	6.5%
208	Neuroma	6.5%
209	Papilloma	6.5%
210	Pseudomyxoma Peritonei	6.5%
211	Seminoma	6.5%
212	Papillomatosis	6.5%
213	Angiolipoma	6.5%
214	Myelolipoma	6.5%
215	Neoplasms, Bone Tissue	6.5%
216	Neoplasms, Fibrous Tissue	6.5%
217	Smooth Muscle Tumor	6.5%
218	Adenomatosis, Pulmonary	6.5%
219	Adenomatous Polyps	6.5%
220	Carcinoma, Large Cell	6.5%
221	Hypoalbuminemia	6.5%
222	Carcinoma, Small Cell	6.5%
223	Desmoplastic Small Round Cell Tumor	6.5%
224	Chondroma	6.5%
225	Hypereosinophilic syndrome	6.5%
226	Enchondroma	6.5%
227	Thrombotic Microangiopathies	6.5%
228	Multiple Endocrine Neoplasia	6.3%
229	Autoimmune thrombocytopenia	6.3%
230	Immune thrombocytopenic purpura	6.3%
231	Neoplasms, Radiation-Induced	6.2%
232	Retinoblastoma	6.2%
233	Ganglioneuroblastoma	6.2%
234	Hypergammaglobulinemia	6.1%
235	Sarcoma 180	6.1%
236	Pheochromocytoma	6%
237	Alveolar rhabdomyosarcoma	6%
238	Transfusion-Related Acute Lung Injury	6%
239	Ecchymosis	5.9%
240	Petechiae	5.9%
241	Purpura	5.9%
242	Heavy Chain Disease	5.9%
243	Lymphomatoid Granulomatosis	5.8%
244	Neurofibrosarcoma	5.8%
245	Hemolytic-Uremic Syndrome	5.6%
246	Abdominal Neoplasms	5.6%
247	Adenitis	5.6%
248	Erythroplasia	5.6%
249	Follicular cyst	5.6%
250	Head and Neck Neoplasms	5.6%
251	Histiocytosis	5.6%
252	Lymphadenitis	5.6%
253	Lymphangitis	5.6%
254	Lymphedema	5.6%
255	Mucocele	5.6%
256	Pilonidal Cyst	5.6%
257	Purpura, Hyperglobulinemic	5.6%
258	Soft Tissue Neoplasms	5.6%
259	Splenic Diseases	5.6%
260	Thoracic Neoplasms	5.6%
261	Thymus Hyperplasia	5.6%
262	Thyroglossal Cyst	5.6%
263	Synovial Cyst	5.6%
264	Pseudolymphoma	5.6%
265	Lymphadenopathy	5.6%
266	Aberrant Crypt Foci	5.6%
267	Carcinoid Heart Disease	5.5%
268	Paraneoplastic Encephalomyelitis	5.4%
269	Mammary Neoplasms, Experimental	5.3%
270	Sickle Cell Trait	5.2%
271	Nephroblastoma	5.1%
272	Thrombocytopenic purpura	5%
273	Lymphopenia	5%
274	Hydrops Fetalis	4.9%
275	Primary amyloidosis	4.9%
276	Job Syndrome	4.9%
277	Adenoid Cystic Carcinoma	4.8%
278	fibroma	4.8%
279	Fibromatosis	4.8%
280	Neutropenia	4.8%
281	Osteoblastoma	4.8%
282	Osteoma	4.8%
283	Rhabdomyoma	4.8%
284	Chondromatosis	4.8%
285	Adenocarcinoma, Clear Cell	4.8%
286	Cholangiocarcinoma	4.8%
287	Cervical Intraepithelial Neoplasia	4.8%
288	Hemangioblastoma	4.8%
289	Lymphoma, Extranodal NK-T-Cell	4.8%
290	Lymphoma, Follicular	4.8%
291	T-Cell Lymphoma	4.8%
292	Mantle cell lymphoma	4.8%
293	Basal Cell Nevus Syndrome	4.6%
294	Tuberous Sclerosis	4.6%
295	Carcinoma, Pancreatic Ductal	4.4%
296	Waterhouse-Friderichsen Syndrome	4.4%
297	Digestive System Neoplasms	4.4%
298	Endocrine Gland Neoplasms	4.4%
299	Eye Neoplasms	4.4%
300	Nervous System Neoplasms	4.4%
301	Atypical Hemolytic Uremic Syndrome	4.4%
302	Acoustic Neuroma	4.4%
303	Hepatocellular Adenoma	4.3%
304	Bone neoplasms	4.2%
305	Leukoplakia	4.2%
306	Lymphoproliferative Disorders	4.2%
307	Pancreatic Cyst	4.2%
308	Skin Neoplasms	4.2%
309	Lymphatic Abnormalities	4.2%
310	Mesoblastic Nephroma	4.2%
311	Barrett Esophagus	4.2%
312	Breast Cyst	4.2%
313	Hydatidiform Mole	4.2%
314	Actinic keratosis	4.2%
315	Mediastinal Cyst	4.2%
316	Neoplasm Invasiveness	4.2%
317	Neoplasm Metastasis	4.2%
318	Neoplasm Recurrence, Local	4.2%
319	Parovarian Cyst	4.2%
320	Pericardial Cyst	4.2%
321	Thymic Cyst	4.2%
322	Carcinogenesis	4.2%
323	Myxoid cyst	4.2%
324	Metastasis	4.2%
325	Acute Chest Syndrome	4%
326	Fibromatosis, Aggressive	4%
327	Fibromatosis, Abdominal	4%
328	Klatskin Tumor	4%
329	Febrile Neutropenia	4%
330	Mastocytosis	4%
331	Sturge-Weber Syndrome	4%
332	Eosinophilia-Myalgia Syndrome	4%
333	Lymphangiectasis, Intestinal	3.9%
334	Optic Nerve Glioma	3.9%
335	Chronic granulomatous disease	3.9%
336	Shwartzman Phenomenon	3.9%
337	Gastrointestinal Stromal Tumors	3.9%
338	Scurvy	3.9%
339	Purpura Fulminans	3.9%
340	neurofibroma	3.9%
341	Eosinophilic Granuloma	3.8%
342	Multiple Endocrine Neoplasia Type 1	3.7%
343	Kernicterus	3.7%
344	Vipoma	3.7%
345	Prolactinoma	3.7%
346	Growth Hormone-Secreting Pituitary Adenoma	3.7%
347	Pulmonary Eosinophilia	3.7%
348	Eosinophilic Pneumonia	3.7%
349	Lymphoma, T-Cell, Cutaneous	3.7%
350	Lymphoma, AIDS-Related	3.7%
351	Enteropathy-Associated T-Cell Lymphoma	3.7%
352	Primary Effusion Lymphoma	3.7%
353	Mastocytoma	3.6%
354	Sezary Syndrome	3.6%
355	Mastocytosis, Systemic	3.6%
356	Anemia, Pernicious	3.6%
357	Parathyroid Neoplasms	3.4%
358	Peritoneal Neoplasms	3.4%
359	Thyroid Neoplasm	3.4%
360	Thyroid carcinoma	3.4%
361	Mucocutaneous Lymph Node Syndrome	3.3%
362	Liver Neoplasms, Experimental	3.3%
363	Corpus Luteum Cyst	3.3%
364	Ovarian Cysts	3.3%
365	Elephantiasis	3.3%
366	Hypersplenism	3.3%
367	Retroperitoneal Neoplasms	3.3%
368	Sarcoidosis	3.3%
369	POEMS Syndrome	3.3%
370	Elephantiasis Nostras Verrucosa	3.3%
371	granulosa cell tumor	3.2%
372	Carcinoma, Ovarian Epithelial	3.2%
373	Adenomatous Polyposis Coli	3.2%
374	Mycosis Fungoides	3.1%
375	Lymphomatoid Papulosis	3.1%
376	Plasmablastic lymphoma	3.1%
377	insulinoma	3%
378	Pancreatic Neoplasm	2.9%
379	Choledochal Cyst	2.8%
380	Tracheal Neoplasms	2.8%
381	Adrenocortical carcinoma	2.8%
382	Peutz-Jeghers Syndrome	2.7%
383	Leukoplakia, Oral	2.7%
384	Paraneoplastic Cerebellar Degeneration	2.7%
385	Gastrinoma	2.7%
386	Glucagonoma	2.7%
387	Burkitt Lymphoma	2.6%
388	Nasopharyngeal carcinoma	2.6%
389	Leydig Cell Tumor	2.6%
390	Granuloma	2.5%
391	Mouth Neoplasms	2.5%
392	Splenic Infarction	2.5%
393	Central Nervous System Neoplasms	2.5%
394	Vascular Neoplasms	2.5%
395	Dupuytren Contracture	2.5%
396	Genital Neoplasms, Female	2.5%
397	Histiocytosis, Langerhans-Cell	2.5%
398	Pancreatic Pseudocyst	2.5%
399	Tumor Lysis Syndrome	2.5%
400	Lymphatic Metastasis	2.4%
401	Neoplasms, Unknown Primary	2.4%
402	Leukemic Infiltration	2.4%
403	Breast Neoplasms, Male	2.4%
404	Neoplasm Micrometastasis	2.4%
405	Triple Negative Breast Neoplasms	2.4%
406	Urticaria Pigmentosa	2.4%
407	Renal Cell Carcinoma	2.4%
408	Papillary Renal Cell Carcinoma	2.4%
409	Esophageal Neoplasms	2.3%
410	Denys-Drash Syndrome	2.3%
411	Limbic Encephalitis	2.3%
412	Carcinoma, Endometrioid	2.3%
413	Pseudoxanthoma Elasticum	2.2%
414	Thyroid Nodule	2.2%
415	Lymphohistiocytosis, Hemophagocytic	2.2%
416	Erdheim-Chester Disease	2.2%
417	Lambert-Eaton Myasthenic Syndrome	2.1%
418	Testicular Neoplasms	2.1%
419	Adrenal Gland Neoplasms	2%
420	Gastrointestinal Neoplasms	2%
421	Genital Neoplasms, Male	2%
422	Liver neoplasms	2%
423	Splenic Rupture	2%
424	Uveal Neoplasms	2%
425	Urologic Neoplasms	2%
426	Sebaceous Gland Neoplasms	2%
427	Spinal Neoplasms	2%
428	Polycystic Ovary Syndrome	1.9%
429	Opsoclonus-Myoclonus Syndrome	1.8%
430	Autoimmune Lymphoproliferative Syndrome	1.7%
431	Xeroderma Pigmentosum	1.7%
432	Myelitis, Transverse	1.6%
433	Meningeal Neoplasms	1.6%
434	Sarcoidosis, Pulmonary	1.6%
435	Nose Neoplasms	1.5%
436	Palatal Neoplasms	1.4%
437	ovarian neoplasm	1.4%
438	Pituitary Adenoma	1.3%
439	Pituitary Neoplasms	1.3%
440	Ear Neoplasms	1.3%
441	Eyelid Neoplasms	1.3%
442	Lung Neoplasms	1.3%
443	Pleural Neoplasms	1.3%
444	Cell Transformation, Viral	1.3%
445	Brain Neoplasms	1.3%
446	Salivary Gland Neoplasms	1.3%
447	Spinal Cord Neoplasms	1.3%
448	Tongue Neoplasms	1.3%
449	Splenosis	1.3%
450	Uterine Neoplasms	1.3%
451	Vaginal Neoplasms	1.3%
452	Vulvar Neoplasms	1.3%
453	Uterine Cancer	1.3%
454	Fallopian Tube Neoplasms	1.3%
455	Meningeal Carcinomatosis	1.2%
456	Pharyngeal Neoplasms	1.1%
457	Central Nervous System Cysts	1.1%
458	Bile Duct Neoplasms	1.1%
459	gallbladder neoplasm	1.1%
460	Intestinal Neoplasms	1.1%
461	Penile Neoplasms	1.1%
462	Prostatic Neoplasms	1.1%
463	Stomach Neoplasms	1.1%
464	Zollinger-Ellison syndrome	1.1%
465	Bronchial Neoplasms	1%
466	Multiple Pulmonary Nodules	1%
467	Laryngeal neoplasm	1%
468	Supratentorial Neoplasms	1%
469	Endometrial Neoplasms	1%
470	Bladder Neoplasm	0.9%
471	Kidney Neoplasm	0.9%
472	Ureteral Neoplasms	0.9%
473	Urethral Neoplasms	0.9%
474	Hypopharyngeal Neoplasms	0.8%
475	Pleural Effusion, Malignant	0.8%
476	Hypopharyngeal Cancer	0.8%
477	Parotid Neoplasms	0.8%
478	Prostatic Neoplasms, Castration-Resistant	0.8%
479	Nelson Syndrome	0.8%
480	Brain Stem Neoplasms	0.8%
481	Choroid Plexus Papilloma	0.7%
482	Cecal Neoplasms	0.7%
483	Duodenal Neoplasms	0.7%
484	Tonsillar Neoplasms	0.7%
485	Cerebellar Neoplasms	0.7%
486	Nasopharyngeal Neoplasms	0.6%
487	Colorectal Neoplasms	0.6%
488	Radicular Cyst	0.6%
489	Appendiceal Neoplasms	0.6%
490	Colonic Neoplasms	0.6%
491	Rectal Neoplasms	0.6%
492	Paranasal Sinus Neoplasms	0.5%
493	Maxillary Sinus Neoplasms	0.4%
494	Anus Neoplasms	0.4%
495	Sigmoid Neoplasms	0.4%
496	Niemann-Pick Disease, Type C	0.4%

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