MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Paraneoplastic Syndromes

(UMLS:C0030472)

Definition:: In patients with neoplastic diseases a wide variety of clinical pictures which are indirect and usually remote effects produced by tumor cell metabolites or other products.
UMLS ID:: C0030472
MeSH ID:: D010257

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.730

Synonym(s)

Paraneoplastic Syndromes

PARANEOPLASTIC SYNDROME

Paraneoplastic Syndrome

Paraneoplastic syndrome

Paraneoplastic syndromes

paraneoplastic syndrome

paraneoplastic syndromes

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Fluorouracil	18424388	CTD
2	Indomethacin	16537180	CTD
3	Octreotide	10509161	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Hamartoma	33.3%
2	Neoplasms, Hormone-Dependent	33.3%
3	Neoplasms, Multiple Primary	33.3%
4	Precancerous Conditions	33.3%
5	Neoplasms, Second Primary	33.3%
6	Carcinoma 256, Walker	25.8%
7	Carcinoma, Ehrlich Tumor	25.3%
8	Dermoid Cyst	25.3%
9	Carcinoma, Lewis Lung	25.3%
10	Neoplasms, Neuroepithelial	24.1%
11	Gliomatosis cerebri	24.1%
12	Neuroectodermal Tumors	23.8%
13	Medulloblastoma	23.4%
14	Abdominal Neoplasms	23.1%
15	Erythroplasia	23.1%
16	Follicular cyst	23.1%
17	Head and Neck Neoplasms	23.1%
18	leukemia	23.1%
19	melanoma	23.1%
20	Mucocele	23.1%
21	Neoplasms, Germ Cell and Embryonal	23.1%
22	Neoplasms, Glandular and Epithelial	23.1%
23	Pilonidal Cyst	23.1%
24	Soft Tissue Neoplasms	23.1%
25	Thoracic Neoplasms	23.1%
26	Thyroglossal Cyst	23.1%
27	Synovial Cyst	23.1%
28	Germ Cell Cancer	23.1%
29	Aberrant Crypt Foci	23.1%
30	Carcinosarcoma	22.4%
31	Hemangiosarcoma	22.4%
32	Leukemia L1210	22.4%
33	Leukemia P388	22.4%
34	lymphangiosarcoma	22.4%
35	Acanthoma	22.4%
36	Adenoma, Acidophil	22%
37	Ganglioneuroma	22%
38	Glioma	22%
39	Malignant Glioma	22%
40	Sarcoma 180	21.6%
41	Carcinoid Tumor	21.5%
42	Neurilemmoma	21.5%
43	Hutchinson's Melanotic Freckle	21.5%
44	Melanoma, Amelanotic	21.5%
45	Melanoma, Experimental	21.1%
46	Cyst	21.1%
47	Neoplastic Processes	21.1%
48	Neoplastic Syndromes, Hereditary	21.1%
49	Pregnancy Complications, Neoplastic	21.1%
50	Astrocytoma	21%
51	Ependymoma	21%
52	oligodendroglioma	21%
53	Ganglioglioma	21%
54	gliosarcoma	21%
55	Anaplastic astrocytoma	21%
56	Anaplastic Oligodendroglioma	21%
57	Basal cell carcinoma	20.9%
58	Carcinoma, Papillary	20.9%
59	Squamous cell carcinoma	20.9%
60	Chondrosarcoma	20.9%
61	Craniopharyngioma	20.9%
62	Cystadenoma	20.9%
63	leiomyosarcoma	20.9%
64	liposarcoma	20.9%
65	Mesothelioma	20.9%
66	synovial sarcoma	20.9%
67	Neuroectodermal Tumor, Melanotic	20.9%
68	Angiomyolipoma	20.9%
69	Clear Cell Sarcoma of Soft Tissue	20.9%
70	Alveolar Soft Part Sarcoma	20.9%
71	Neuroendocrine Tumors	20.9%
72	Sarcoma, Myeloid	20.9%
73	Carcinoma, Basal Cell	20.9%
74	Malignant Carcinoid Syndrome	20.8%
75	Neoplasms, Experimental	20.5%
76	Glioblastoma	20.5%
77	Neuroblastoma	20.5%
78	Glioblastoma Multiforme	20.5%
79	Ganglioneuroblastoma	20.3%
80	Multiple Endocrine Neoplasia	20.2%
81	Cystadenocarcinoma	20.2%
82	Fibrosarcoma	20.2%
83	Osteosarcoma	20.2%
84	Mucoepidermoid Carcinoma	20.2%
85	Adenofibroma	19.9%
86	Fibroadenoma	19.9%
87	Malignant Fibrous Histiocytoma	19.9%
88	Trophoblastic Neoplasms	19.6%
89	Bowen's Disease	19.5%
90	Paraganglioma	19.5%
91	Rhabdomyosarcoma	19.5%
92	Giant Cell Tumor of Bone	19.5%
93	Leukemia, Experimental	19.5%
94	Mammary Neoplasms, Experimental	19.5%
95	Meningioma	19.5%
96	Dermatofibrosarcoma	19.2%
97	Dermatofibrosarcoma Protuberans	19.2%
98	Pheochromocytoma	18.9%
99	Alveolar rhabdomyosarcoma	18.9%
100	Choriocarcinoma	18.6%
101	Carcinoma, Lobular	18.6%
102	Adenoma	18.5%
103	Ameloblastoma	18.5%
104	Angiokeratoma	18.5%
105	Carcinoma	18.5%
106	Chordoma	18.5%
107	Hemangioma	18.5%
108	hemangiopericytoma	18.5%
109	Lymphangioma	18.5%
110	Mesenchymoma	18.5%
111	Nevus	18.5%
112	Retroperitoneal Neoplasms	18.5%
113	Teratoma	18.5%
114	Hepatoblastoma	18.5%
115	Mixed Tumor, Mullerian	18.5%
116	Germinoma	18.5%
117	Teratocarcinoma	18.5%
118	Angiofibroma	18.5%
119	Sarcoma	18.5%
120	Epithelioma	18.5%
121	Sarcoma, Experimental	18.4%
122	Thymoma	16.5%
123	Carcinoid Heart Disease	16.5%
124	Multiple Endocrine Neoplasia Type 1	16.5%
125	Leukemia, Plasma Cell	16.4%
126	Adenocarcinoma	16.4%
127	Carcinoma in Situ	16.4%
128	Carcinoma, Transitional Cell	16.4%
129	Phyllodes Tumor	16.4%
130	Dysgerminoma	16.4%
131	Hemangioendothelioma	16.4%
132	Lipoma	16.4%
133	Myoma	16.4%
134	Myxoma	16.4%
135	Neuroma	16.4%
136	Papilloma	16.4%
137	Pseudomyxoma Peritonei	16.4%
138	Seminoma	16.4%
139	Papillomatosis	16.4%
140	Angiolipoma	16.4%
141	Myelolipoma	16.4%
142	Neoplasms, Bone Tissue	16.4%
143	Neoplasms, Fibrous Tissue	16.4%
144	Smooth Muscle Tumor	16.4%
145	Adenomatosis, Pulmonary	16.4%
146	Adenomatous Polyps	16.4%
147	Carcinoma, Large Cell	16.4%
148	Carcinoma, Small Cell	16.4%
149	Desmoplastic Small Round Cell Tumor	16.4%
150	Chondroma	16.4%
151	Enchondroma	16.4%
152	Digestive System Neoplasms	15.8%
153	Endocrine Gland Neoplasms	15.8%
154	Eye Neoplasms	15.8%
155	Nervous System Neoplasms	15.8%
156	Leukemia, Radiation-Induced	15.6%
157	Adenoid Cystic Carcinoma	15.3%
158	fibroma	15.3%
159	Fibromatosis	15.3%
160	Osteoblastoma	15.3%
161	Osteoma	15.3%
162	Rhabdomyoma	15.3%
163	Chondromatosis	15.3%
164	Adenocarcinoma, Clear Cell	15.3%
165	Cholangiocarcinoma	15.3%
166	Cervical Intraepithelial Neoplasia	15.3%
167	Hemangioblastoma	15.3%
168	Lymphoma, Extranodal NK-T-Cell	15.3%
169	Bone neoplasms	15%
170	Leukoplakia	15%
171	Lymphocele	15%
172	Pancreatic Cyst	15%
173	Skin Neoplasms	15%
174	Hematologic Neoplasms	15%
175	Neoplasms, Radiation-Induced	15%
176	Hydatidiform Mole	14.8%
177	Fibromatosis, Aggressive	14.8%
178	Fibromatosis, Abdominal	14.8%
179	Klatskin Tumor	14.8%
180	Retinoblastoma	14.8%
181	Barrett Esophagus	14.6%
182	Breast Cyst	14.6%
183	Histiocytic Disorders, Malignant	14.6%
184	Actinic keratosis	14.6%
185	Mediastinal Cyst	14.6%
186	Neoplasm Invasiveness	14.6%
187	Neoplasm Metastasis	14.6%
188	Neoplasm Recurrence, Local	14.6%
189	Parovarian Cyst	14.6%
190	Pericardial Cyst	14.6%
191	Splenic Neoplasms	14.6%
192	Thymic Cyst	14.6%
193	Carcinogenesis	14.6%
194	Myxoid cyst	14.6%
195	Metastasis	14.6%
196	Carcinoma, Pancreatic Ductal	14.5%
197	Parathyroid Neoplasms	14.3%
198	Peritoneal Neoplasms	14.3%
199	Thyroid Neoplasm	14.3%
200	Thyroid carcinoma	14.3%
201	Acoustic Neuroma	14%
202	Lymphomatoid Granulomatosis	13.9%
203	Neurofibrosarcoma	13.9%
204	Vipoma	13.8%
205	Composite Lymphoma	13.7%
206	Tracheal Neoplasms	13.5%
207	Leukoplakia, Oral	13.1%
208	Basal Cell Nevus Syndrome	12.6%
209	Tuberous Sclerosis	12.5%
210	Optic Nerve Glioma	12.4%
211	Endometrial Stromal Sarcoma	12.4%
212	Thyroid Nodule	12.3%
213	Hepatocellular Adenoma	12.3%
214	Mouth Neoplasms	12.2%
215	Central Nervous System Neoplasms	12.2%
216	Vascular Neoplasms	12.2%
217	Thymus Neoplasms	12.2%
218	Lymphangioleiomyomatosis	12.2%
219	Liver Neoplasms, Experimental	12.1%
220	insulinoma	12.1%
221	Gastrinoma	11.9%
222	Glucagonoma	11.9%
223	Genital Neoplasms, Female	11.9%
224	Pancreatic Neoplasm	11.9%
225	Pancreatic Pseudocyst	11.9%
226	Plasmacytoma	11.9%
227	Malignant histiocytosis	11.8%
228	Lymphatic Metastasis	11.8%
229	Neoplasms, Unknown Primary	11.8%
230	Leukemic Infiltration	11.8%
231	Breast Neoplasms, Male	11.8%
232	Histiocytic sarcoma	11.8%
233	Neoplasm Micrometastasis	11.8%
234	Triple Negative Breast Neoplasms	11.8%
235	Nephroblastoma	11.4%
236	Esophageal Neoplasms	10.9%
237	Lymphoma	10.7%
238	Meningeal Neoplasms	10.6%
239	Corpus Luteum Cyst	10.6%
240	Ovarian Cysts	10.6%
241	Leukemia, Myelomonocytic, Chronic	10.5%
242	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	10.5%
243	Leydig Cell Tumor	10.3%
244	Prolactinoma	10.1%
245	Growth Hormone-Secreting Pituitary Adenoma	10.1%
246	Mastocytoma	9.9%
247	Meningeal Carcinomatosis	9.8%
248	Mastocytosis, Systemic	9.8%
249	Leukemia, Myeloid, Chronic-Phase	9.8%
250	Adenomatous Polyposis Coli	9.5%
251	Adrenocortical carcinoma	9.4%
252	Testicular Neoplasms	9.4%
253	Adrenal Gland Neoplasms	9.1%
254	Gastrointestinal Neoplasms	9.1%
255	Genital Neoplasms, Male	9.1%
256	Liver neoplasms	9.1%
257	Uveal Neoplasms	9.1%
258	Paraneoplastic Encephalomyelitis	9.1%
259	Urologic Neoplasms	8.9%
260	Mesoblastic Nephroma	8.8%
261	Sebaceous Gland Neoplasms	8.8%
262	Spinal Neoplasms	8.8%
263	Bone Marrow Neoplasms	8.8%
264	Hodgkin Disease	8.6%
265	Lymphoma, Non-Hodgkin	8.6%
266	Choledochal Cyst	8.6%
267	Polycystic Ovary Syndrome	8.6%
268	granulosa cell tumor	8.6%
269	Carcinoma, Ovarian Epithelial	8.6%
270	Palatal Neoplasms	8.4%
271	Peutz-Jeghers Syndrome	8.3%
272	Ear Neoplasms	8.1%
273	Eyelid Neoplasms	8.1%
274	Lung Neoplasms	8.1%
275	Pleural Neoplasms	8.1%
276	Renal Cell Carcinoma	8%
277	Papillary Renal Cell Carcinoma	8%
278	Mastocytosis	8%
279	Sturge-Weber Syndrome	8%
280	Cell Transformation, Viral	7.9%
281	Nose Neoplasms	7.9%
282	Carcinoma, Endometrioid	7.9%
283	Brain Neoplasms	7.8%
284	Salivary Gland Neoplasms	7.8%
285	Spinal Cord Neoplasms	7.8%
286	Tongue Neoplasms	7.8%
287	Gastrointestinal Stromal Tumors	7.8%
288	Hemangioma, Cavernous	7.8%
289	Leukemia, T-Cell	7.7%
290	Uterine Neoplasms	7.7%
291	Vaginal Neoplasms	7.7%
292	Vulvar Neoplasms	7.7%
293	Uterine Cancer	7.7%
294	Leukemia, B-Cell	7.7%
295	Fallopian Tube Neoplasms	7.7%
296	neurofibroma	7.7%
297	Lymphoma, Follicular	7.6%
298	T-Cell Lymphoma	7.6%
299	Mantle cell lymphoma	7.6%
300	Bronchial Neoplasms	7.5%
301	Multiple Pulmonary Nodules	7.4%
302	Dupuytren Contracture	7.3%
303	Supratentorial Neoplasms	7.2%
304	Endometrial Neoplasms	7.2%
305	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	7.2%
306	Leukemia, Large Granular Lymphocytic	7.2%
307	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	7.2%
308	Lymphoma, T-Cell, Cutaneous	7.1%
309	Lymphoma, AIDS-Related	7.1%
310	Enteropathy-Associated T-Cell Lymphoma	7.1%
311	Primary Effusion Lymphoma	7.1%
312	Nasopharyngeal carcinoma	7.1%
313	Urticaria Pigmentosa	7.1%
314	Brain Stem Neoplasms	6.9%
315	Mycosis Fungoides	6.9%
316	Lymphomatoid Papulosis	6.9%
317	Plasmablastic lymphoma	6.9%
318	Primary amyloidosis	6.9%
319	Denys-Drash Syndrome	6.8%
320	Choroid Plexus Papilloma	6.8%
321	Pituitary Adenoma	6.8%
322	Pituitary Neoplasms	6.8%
323	Pharyngeal Neoplasms	6.5%
324	Central Nervous System Cysts	6.3%
325	Bile Duct Neoplasms	6.2%
326	gallbladder neoplasm	6.2%
327	Intestinal Neoplasms	6.2%
328	Penile Neoplasms	6.2%
329	Prostatic Neoplasms	6.2%
330	Stomach Neoplasms	6.2%
331	Paraneoplastic Cerebellar Degeneration	6.2%
332	Polycythemia Vera	6.1%
333	Hypopharyngeal Neoplasms	5.8%
334	Pleural Effusion, Malignant	5.8%
335	Hypopharyngeal Cancer	5.8%
336	ovarian neoplasm	5.7%
337	Parotid Neoplasms	5.7%
338	Prostatic Neoplasms, Castration-Resistant	5.7%
339	Nelson Syndrome	5.7%
340	Tonsillar Neoplasms	5.5%
341	Cerebellar Neoplasms	5.5%
342	Laryngeal neoplasm	5.4%
343	Bladder Neoplasm	5.1%
344	Kidney Neoplasm	5.1%
345	Ureteral Neoplasms	5.1%
346	Urethral Neoplasms	5.1%
347	Limbic Encephalitis	5.1%
348	Waldenstrom Macroglobulinemia	4.9%
349	Multiple Myeloma	4.9%
350	Cecal Neoplasms	4.7%
351	Duodenal Neoplasms	4.7%
352	Burkitt Lymphoma	4.7%
353	Sezary Syndrome	4.6%
354	Radicular Cyst	4.6%
355	Xeroderma Pigmentosum	4.6%
356	Appendiceal Neoplasms	4.5%
357	Colonic Neoplasms	4.5%
358	Rectal Neoplasms	4.5%
359	Lambert-Eaton Myasthenic Syndrome	4.4%
360	Nasopharyngeal Neoplasms	4.1%
361	Colorectal Neoplasms	4%
362	Opsoclonus-Myoclonus Syndrome	3.8%
363	Anus Neoplasms	3.8%
364	Sigmoid Neoplasms	3.8%
365	Paranasal Sinus Neoplasms	3.6%
366	Maxillary Sinus Neoplasms	3.4%
367	Myelitis, Transverse	3.4%

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