MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Persistent Vegetative State

(UMLS:C0242670)

Definition:: Vegetative state refers to the neurocognitive status of individuals with severe brain damage, in whom physiologic functions (sleep-wake cycles, autonomic control, and breathing) persist, but awareness (including all cognitive function and emotion) is abolished.
UMLS ID:: C0242670
MeSH ID:: D018458

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.140.140.627|C10.597.606.358.800.400

Classification 2:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.888.592.604.359.800.400

Synonym(s)

Persistent Vegetative State

Chronic vegetative state

PVS - Persistent vegetative state

Persistent vegetative state

chronic vegetative state

persistent state vegetative

persistent vegetative state

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Levodopa	10654305	CTD
2	Methotrexate	17355553	CTD
3	Zolpidem	18226667	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Syncope	40.6%
2	Stupor	40.6%
3	Presyncope	40.6%
4	Brain Death	27%
5	Cerebral Palsy	25.1%
6	Asterixis	25.1%
7	Ballismus	25.1%
8	Decerebrate State	22.5%
9	Hemiparesis	22.5%
10	Meningism	22.5%
11	Paresis	22.5%
12	Seizures	22.5%
13	Sensation Disorders	22.5%
14	Complex partial seizures	22.5%
15	Monoparesis	22.5%
16	Gait Disorders, Neurologic	22.5%
17	Neuromuscular Manifestations	22.5%
18	Confusion	21.4%
19	Lethargy	21.4%
20	Memory Disorders	21.4%
21	Perceptual Disorders	21.4%
22	Psychomotor Disorders	21.4%
23	Anhedonia	21.4%
24	Disorientation	21.4%
25	Memory Loss	21.4%
26	Hemisensory Neglect	21.4%
27	Meningoencephalitis	21.3%
28	Encephalomyelitis	20.4%
29	Subdural Effusion	20%
30	Multiple System Atrophy	19.7%
31	Pupil Disorders	19.4%
32	Sleep Wake Disorders	19.3%
33	Akinetic Mutism	18.9%
34	Anoxic Encephalopathy	18.9%
35	Basal Ganglia Diseases	18.9%
36	Cerebellar Diseases	18.9%
37	Encephalitis	18.9%
38	Encephalomalacia	18.9%
39	Epilepsy	18.9%
40	Hydrocephalus	18.9%
41	Congenital Hydrocephalus	18.9%
42	Hypothalamic Diseases	18.9%
43	Thalamic Diseases	18.9%
44	Intracranial Hypertension	18.9%
45	Aura	18.9%
46	Leukoencephalopathy	18.9%
47	Neuroaxonal Dystrophies	18.9%
48	Headache Disorders	18.9%
49	Intracranial Hypotension	18.9%
50	Brain Edema	18.9%
51	Brain Hypoxia	18.9%
52	Aqueductal Stenosis	18.9%
53	Dandy-Walker Syndrome	18.9%
54	Vertigo	18.7%
55	Mental Retardation	18.6%
56	Mental deficiency	18.6%
57	Intellectual Disability	18.6%
58	Catatonia	18.4%
59	Dementia, Vascular	17.9%
60	Lewy Body Disease	17.9%
61	Pneumocephalus	17.9%
62	Parkinsonian Disorders	17.4%
63	Akathisia	17.4%
64	Restlessness	17.4%
65	Psychomotor Agitation	17.4%
66	Posterior Leukoencephalopathy Syndrome	17.2%
67	Posterior reversible encephalopathy syndrome	17.2%
68	Basal Ganglia Cerebrovascular Disease	16.6%
69	Ocular Motility Disorders	16.6%
70	Cyclophoria	16.6%
71	Voice Disorders	16.4%
72	Voice Disturbance	16.4%
73	Amblyopia	16.4%
74	Brain Abscess	16.4%
75	Marchiafava-Bignami Disease	16.3%
76	Coma, Post-Head Injury	16.1%
77	Alice in Wonderland Syndrome	16%
78	Meningitis	16%
79	Movement Disorders	16%
80	Pachymeningitis	16%
81	Spinal Cord Diseases	16%
82	Amnesia, Transient Global	15.9%
83	Epilepsy, Post-Traumatic	15.8%
84	Brain Injuries	15.7%
85	Brain Neoplasms	15.7%
86	Progressive supranuclear palsy	15.5%
87	Brain Diseases, Metabolic	15.4%
88	Cerebrovascular Disorders	15.4%
89	Cerebrovascular Insufficiency	15.4%
90	Dementia	15.4%
91	Parkinson Disease	15.4%
92	Language Disorders	15.2%
93	Myelitis	14.9%
94	Cranial nerve diseases	14.8%
95	Demyelinating Diseases	14.8%
96	Demyelination	14.8%
97	Neuromuscular Diseases	14.8%
98	Chronobiology Disorders	14.8%
99	Meige Syndrome	14.7%
100	Cerebral Ventriculitis	14.7%
101	Myoclonic Epilepsy	14.6%
102	Epilepsy, Temporal Lobe	14.6%
103	Epilepsy, Rolandic	14.6%
104	Benign Rolandic Epilepsy	14.6%
105	Cerebellar Ataxia	14.5%
106	Stiff-Person Syndrome	14.5%
107	Vascular Headaches	14.5%
108	Hypoxia-Ischemia, Brain	14.4%
109	Chorea	14.4%
110	Leukomalacia, Periventricular	14.3%
111	Ophthalmoplegic Migraine	14.3%
112	Gait Ataxia	14.2%
113	Gait Apraxia	14.1%
114	Epidural Abscess	14.1%
115	Auditory Perceptual Disorders	14.1%
116	Reflex, Abnormal	14%
117	Hyporeflexia	14%
118	Hyperreflexia	14%
119	Prion Diseases	13.8%
120	Orthostatic intolerance	13.8%
121	Huntington Disease	13.6%
122	Neuroleptic Malignant Syndrome	13.6%
123	Myelinolysis, Central Pontine	13.6%
124	Neurogenic Inflammation	13.6%
125	Subacute Combined Degeneration	13.5%
126	Cerebellar Neoplasms	13.4%
127	Central Nervous System Infection	13.3%
128	Dyskinesia, Drug-Induced	13.3%
129	Dystonia Musculorum Deformans	13.2%
130	Striatonigral Degeneration	12.9%
131	Alexia	12.8%
132	Dyslexia	12.8%
133	Agnosia	12.7%
134	Apraxias	12.7%
135	Hallucinations	12.7%
136	Visual Agnosia	12.7%
137	Anosognosia	12.7%
138	Wernicke-Korsakoff Syndrome	12.7%
139	Psychophysiologic Disorders	12.7%
140	Motor Neuron Disease	12.6%
141	Leukoencephalopathy, Progressive Multifocal	12.5%
142	Anosmia	12.4%
143	Ataxia	12.4%
144	Athetosis	12.4%
145	Catalepsy	12.4%
146	Dystonia	12.4%
147	Hemiplegia	12.4%
148	Locked-In Syndrome	12.4%
149	Muscle Hypertonia	12.4%
150	Muscle hypotonia	12.4%
151	Myoclonus	12.4%
152	Myotonia	12.4%
153	Paraplegia	12.4%
154	Pseudobulbar Palsy	12.4%
155	Quadriplegia	12.4%
156	Spasm	12.4%
157	Spastic Paraplegia	12.4%
158	Status Epilepticus	12.4%
159	Taste Disorders	12.4%
160	Tremor	12.4%
161	Monoplegia	12.4%
162	Hypokinesia	12.4%
163	Paraparesis	12.4%
164	Bradykinesia	12.4%
165	Waxy flexibility	12.4%
166	Action Tremor	12.4%
167	Resting Tremor	12.4%
168	Dysosmia	12.4%
169	Quadriparesis	12.4%
170	Olfaction Disorders	12.4%
171	Myokymia	12.4%
172	Somatosensory Disorders	12.4%
173	Hyperkinesia	12.4%
174	Intention tremor	12.4%
175	Epilepsies, Partial	12.4%
176	Epilepsy, Generalized	12.4%
177	Pseudotumor Cerebri	12.4%
178	Hypertensive Encephalopathy	12.4%
179	Simple Partial Seizures	12.4%
180	Epilepsy, Reflex	12.4%
181	Headache Disorders, Primary	12.4%
182	Headache Disorders, Secondary	12.4%
183	Medication overuse headache	12.4%
184	Creutzfeldt-Jakob disease	12.3%
185	Trauma, Nervous System	12.3%
186	Spinal Muscular Atrophy	12.2%
187	Progressive Muscular Atrophy	12.2%
188	Phantom pain	12.1%
189	Phantom Limb Pain	12.1%
190	Juvenile Myoclonic Epilepsy	12%
191	Myoclonic Epilepsies, Progressive	12%
192	Nervous System Neoplasms	12%
193	Neurotoxicity Syndromes	12%
194	Spinal Cord Injuries	11.9%
195	Basal Ganglia Hemorrhage	11.7%
196	Ophthalmoplegia	11.6%
197	External Ophthalmoplegia	11.6%
198	Muscular Atrophy	11.6%
199	Limbic Encephalitis	11.5%
200	Amyotrophic Lateral Sclerosis	11.4%
201	Leukoencephalitis, Acute Hemorrhagic	11.4%
202	Poliomyelitis	11.4%
203	MPTP Poisoning	11.4%
204	Presenile dementia	11.3%
205	Senile dementia	11.3%
206	Polydipsia	11.3%
207	Shy-Drager Syndrome	11.3%
208	Lupus Vasculitis, Central Nervous System	11.3%
209	Muscle Weakness	11.1%
210	Amnesia	11.1%
211	Delirium	11.1%
212	Dissociative Amnesia	11.1%
213	Global Amnesia	11.1%
214	Restless Legs Syndrome	11%
215	Akathisia, Drug-Induced	10.9%
216	Vision Disorders	10.7%
217	Metamorphopsia	10.7%
218	Visual Impairment	10.7%
219	Polyradiculoneuropathy	10.7%
220	Polyradiculoneuritis	10.7%
221	Pituitary Apoplexy	10.6%
222	Anisocoria	10.5%
223	Facial paralysis	10.5%
224	Muscle Cramp	10.5%
225	Tonic Pupil	10.5%
226	Facial Paresis	10.5%
227	Dysacusis	10.5%
228	Brain Infarction	10.5%
229	Cerebrospinal Fluid Otorrhea	10.5%
230	Cerebrospinal Fluid Rhinorrhea	10.5%
231	Asthenia	10.4%
232	Body Temperature Changes	10.4%
233	Cyanosis	10.4%
234	Edema	10.4%
235	Failure to Thrive	10.4%
236	Fatigue	10.4%
237	Feminization	10.4%
238	Fetal Distress	10.4%
239	Motion Sickness	10.4%
240	Signs and Symptoms, Digestive	10.4%
241	Signs and Symptoms, Respiratory	10.4%
242	Skin Manifestations	10.4%
243	Chills	10.4%
244	Lassitude	10.4%
245	Pseudophakia	10.4%
246	Urological Manifestations	10.4%
247	Mobility Limitation	10.4%
248	Somnolence	10.4%
249	Respiratory Paralysis	10.4%
250	Pituitary Diseases	10.4%
251	Encephalomyelitis, Acute Disseminated	10.4%
252	Tetany	10.3%
253	Lafora Disease	10.3%
254	Unverricht-Lundborg Syndrome	10.3%
255	Chronic Fatigue Syndrome	10.3%
256	Vasculitis, Central Nervous System	10.3%
257	Vocal Cord Paralysis	10.3%
258	Meningitis, Bacterial	10.3%
259	Meningitis, Fungal	10.3%
260	Torticollis	10.3%
261	Brain Hemorrhage, Traumatic	10.2%
262	Hepatolenticular Degeneration	10.2%
263	Carotid Artery Injuries	10.2%
264	Pituitary Adenoma	10.2%
265	Pituitary Neoplasms	10.2%
266	Agraphia	10.2%
267	Anomia	10.2%
268	Cluttering	10.2%
269	Language Development Disorders	10.2%
270	Speech Disorders	10.2%
271	Dysgraphia	10.2%
272	Dyslalia	10.2%
273	Brain Injuries, Diffuse	10.1%
274	Traumatic Brain Injury	10.1%
275	Supratentorial Neoplasms	10.1%
276	Renal Colic	10%
277	Abdominal Pain	10%
278	Carotid Artery Diseases	10%
279	Brain Ischemia	10%
280	Cerebrovascular accident	10%
281	Kluver-Bucy Syndrome	10%
282	Vasospasm, Intracranial	10%
283	Intracranial Arterial Diseases	10%
284	Horner Syndrome	9.9%
285	Miller Fisher Syndrome	9.9%
286	Autonomic Dysreflexia	9.9%
287	Complex Regional Pain Syndromes	9.9%
288	Putaminal Hemorrhage	9.8%
289	Paraneoplastic Cerebellar Degeneration	9.7%
290	Opsoclonus-Myoclonus Syndrome	9.5%
291	Hoarseness	9.5%
292	Canavan Disease	9.4%
293	Alexander Disease	9.4%
294	Myelitis, Transverse	9.3%
295	Infarction, Middle Cerebral Artery	9.3%
296	Infarction, Anterior Cerebral Artery	9.3%
297	Infarction, Posterior Cerebral Artery	9.3%
298	Arachnoiditis	9.3%
299	Aseptic Meningitis	9.3%
300	Syringomyelia	9.3%
301	Essential Tremor	9.3%
302	Familial Tremor	9.3%
303	Pneumorrhachis	9.3%
304	Writer's Cramp	9.3%
305	Toxoplasmosis, Cerebral	9.2%
306	Neuralgia	9.2%
307	Neuropathic pain	9.2%
308	Spinal Cord Neoplasms	9.2%
309	Tardive Dyskinesia	9.2%
310	Post-Traumatic Headache	9.1%
311	Tension Headache	9.1%
312	Epilepsy, Complex Partial	9.1%
313	Migraine Disorders	9.1%
314	Abdominal Migraine	9.1%
315	Status Migrainosus	9.1%
316	Cervicogenic Headache	9.1%
317	Friedreich Ataxia	9%
318	Aphonia	8.9%
319	Dysphonia	8.9%
320	Alcohol Withdrawal Seizures	8.9%
321	Eye Manifestations	8.7%
322	Cerebral Infarction	8.6%
323	Brain Stem Infarctions	8.6%
324	Pain	8.5%
325	Ache	8.5%
326	Dyscalculia	8.5%
327	Gerstmann Syndrome	8.5%
328	Prosopagnosia	8.5%
329	Apraxia, Ideomotor	8.5%
330	Charles Bonnet Syndrome	8.5%
331	Alien Hand Syndrome	8.5%
332	Cardiac Output, High	8.5%
333	Myocardial Stunning	8.5%
334	Reticulocytosis	8.5%
335	Low Cardiac Output Syndrome	8.5%
336	Eye pain	8.5%
337	Moyamoya Disease	8.4%
338	Reye Syndrome	8.4%
339	Intracranial Embolism and Thrombosis	8.3%
340	Hepatic Encephalopathy	8.3%
341	Peripheral Nerve Injuries	8.3%
342	Intermittent Claudication	8.3%
343	Myasthenia Gravis	8.2%
344	Jet Lag Syndrome	8.1%
345	Adrenoleukodystrophy	7.9%
346	Dysautonomia	7.8%
347	Vagus Nerve Disorder	7.8%
348	Glossopharyngeal Neuralgia	7.8%
349	Abducens Nerve Diseases	7.8%
350	Heavy Metal Poisoning, Nervous System	7.8%
351	Neuromuscular Junction Diseases	7.8%
352	Tauopathies	7.8%
353	Trochlear Nerve Diseases	7.8%
354	Peripheral Nervous System Diseases	7.8%
355	Guillain-Barre Syndrome	7.7%
356	Mitochondrial Encephalomyopathies	7.7%
357	Aphasia	7.7%
358	Articulation Disorders	7.7%
359	Echolalia	7.7%
360	Stuttering	7.7%
361	Dysphasia	7.7%
362	Lateral Medullary Syndrome	7.7%
363	Central Nervous System Fungal Infections	7.6%
364	Conus Medullaris Syndrome	7.6%
365	Spinal Cord Vascular Diseases	7.6%
366	Cluster Headache	7.5%
367	Migraine with Aura	7.5%
368	Familial Hemiplegic Migraine	7.5%
369	Chronic Paroxysmal Hemicrania	7.5%
370	SUNCT Syndrome	7.5%
371	Paroxysmal Hemicrania	7.5%
372	Lambert-Eaton Myasthenic Syndrome	7.5%
373	Dysgeusia	7.5%
374	Formication	7.5%
375	Hyperalgesia	7.5%
376	Hyperesthesia	7.5%
377	Hypesthesia	7.5%
378	Numbness	7.5%
379	Paresthesia	7.5%
380	Paraparesis, Spastic	7.5%
381	Trismus	7.5%
382	Epilepsia Partialis Continua	7.5%
383	Hypogeusia	7.5%
384	Brown-Sequard Syndrome	7.5%
385	Lockjaw	7.5%
386	Allodynia	7.5%
387	Ageusia	7.5%
388	Empty Sella Syndrome	7.5%
389	Hyperpituitarism	7.5%
390	Hypopituitarism	7.5%
391	Hypophysitis	7.5%
392	Ataxia Telangiectasia	7.5%
393	Diffuse Axonal Injury	7.4%
394	Brain Stem Neoplasms	7.4%
395	Tuberculosis, Meningeal	7.4%
396	Cerebral Arterial Diseases	7.3%
397	Vertebrobasilar Insufficiency	7.3%
398	Basilar Artery Stenosis	7.3%
399	Vertebral Artery Stenosis	7.3%
400	Intracranial Hemorrhage, Hypertensive	7.3%
401	Transient Cerebral Ischemia	7.3%
402	Retrograde amnesia	7.3%
403	Amnesia, Anterograde	7.3%
404	Sleep Disorders, Circadian Rhythm	7.3%
405	Brain Diseases, Metabolic, Inborn	7.2%
406	Subarachnoid Hemorrhage, Traumatic	7.2%
407	Carotid Artery, Internal, Dissection	7.2%
408	Progressive bulbar palsy	7.1%
409	Bulbar palsy	7.1%
410	Scrapie	7.1%
411	Central Cord Syndrome	7.1%
412	Pain, Postoperative	7.1%
413	Hypergammaglobulinemia	7.1%
414	Botulism	7%
415	Central Nervous System Cysts	7%
416	Back Pain	7%
417	Neck Pain	7%
418	Chest Pain	7%
419	Dizziness	7%
420	Facial Pain	7%
421	Flank Pain	7%
422	Headache	7%
423	Pain, Intractable	7%
424	Pelvic Pain	7%
425	Chronic pain	7%
426	Lightheadedness	7%
427	Pain, Referred	7%
428	Throbbing Headache	7%
429	Labor Pain	7%
430	Cancer Pain	7%
431	Nociceptive Pain	7%
432	Pathological Conditions, Anatomical	7%
433	Sarcopenia	6.9%
434	Vertebral Artery Dissection	6.9%
435	Frontotemporal dementia	6.8%
436	MELAS Syndrome	6.8%
437	Subarachnoid Hemorrhage	6.8%
438	Cerebral Hemorrhage	6.8%
439	Causalgia	6.7%
440	Olfactory Nerve Injuries	6.7%
441	Subacute Sclerosing Panencephalitis	6.7%
442	Sleep Deprivation	6.6%
443	Mutism	6.5%
444	Selective Mutism	6.5%
445	Kernicterus	6.5%
446	Myopathy	6.5%
447	Optic Neuropathy	6.5%
448	Dysarthria	6.4%
449	Brain Contusion	6.4%
450	Central Nervous System Bacterial Infections	6.4%
451	Diplopia	6.4%
452	Muscle Rigidity	6.4%
453	Muscle Spasticity	6.4%
454	Scotoma	6.4%
455	Photophobia	6.4%
456	Cogwheel Rigidity	6.4%
457	Hemifacial Spasm	6.4%
458	Amaurosis	6.4%
459	Blindness	6.4%
460	Nuchal Rigidity	6.4%
461	Neuromyelitis Optica	6.3%
462	Facial Nerve Diseases	6.3%
463	Craniocerebral Trauma	6.3%
464	Parasomnia	6.3%
465	Dyssomnias	6.3%
466	Hemianopsia	6.3%
467	Hyperacusis	6.3%
468	Tinnitus	6.3%
469	Phonophobia	6.3%
470	Hearing Loss	6.3%
471	Wernicke Encephalopathy	6.3%
472	AIDS Dementia Complex	6.3%
473	Vestibulocochlear Nerve Diseases	6.2%
474	Hydranencephaly	6.2%
475	Neural Tube Defects	6.2%
476	Tethered Cord Syndrome	6.2%
477	Central Nervous System Neoplasms	6.2%
478	Iniencephaly	6.2%
479	Craniorachischisis	6.2%
480	Exencephaly	6.2%
481	Septo-Optic Dysplasia	6.2%
482	Cortical Dysplasia	6.2%
483	Malformations of Cortical Development	6.2%
484	Brain Concussion	6.2%
485	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	6.2%
486	Sweating, Gustatory	6.2%
487	Auriculotemporal Syndrome	6.2%
488	Carotid Stenosis	6.2%
489	Intracranial Aneurysm	6.2%
490	Neurologic Manifestations	6.2%
491	Intracranial Arteriosclerosis	6.1%
492	Cerebral Atherosclerosis	6.1%
493	Cerebral Arteriosclerosis	6.1%
494	Cerebral Thrombosis	6.1%
495	Intracranial Embolism	6.1%
496	Intracranial Thrombosis	6.1%
497	Hyperprolactinemia	6.1%
498	Choroid Plexus Papilloma	6.1%
499	Subclavian Steal Syndrome	6%
500	Pick Disease of the Brain	6%
501	Sciatica	6%
502	Meningitis, Cryptococcal	6%
503	Meningitis, Listeria	5.9%
504	Multiple Sclerosis	5.9%
505	Meningitis, Haemophilus	5.9%
506	Meningitis, Pneumococcal	5.9%
507	Facial Nerve Injuries	5.9%
508	jaundice	5.8%
509	Cri-du-Chat Syndrome	5.8%
510	Down Syndrome	5.8%
511	Trisomy 21	5.8%
512	Reflex Sympathetic Dystrophy	5.8%
513	Nocturnal Myoclonus Syndrome	5.8%
514	Williams Syndrome	5.8%
515	Abdomen, Acute	5.7%
516	Gastroparesis	5.6%
517	Hematoma, Subdural	5.5%
518	Hematoma, Epidural, Cranial	5.5%
519	Giant Cell Arteritis	5.5%
520	Temporal Arteritis	5.5%
521	Color blindness	5.5%
522	Anorexia	5.4%
523	Anoxia	5.4%
524	Constipation	5.4%
525	Diarrhea	5.4%
526	Dyspepsia	5.4%
527	Eructation	5.4%
528	Fever	5.4%
529	Flatulence	5.4%
530	Flushing	5.4%
531	Halitosis	5.4%
532	Heartburn	5.4%
533	Hiccough	5.4%
534	Hypercalciuria	5.4%
535	Hypercapnia	5.4%
536	Hyperphagia	5.4%
537	Nausea	5.4%
538	Pallor	5.4%
539	Vomiting	5.4%
540	Hypocapnia	5.4%
541	Dyschezia	5.4%
542	Hypoxia	5.4%
543	Hyperoxia	5.4%
544	Lower Urinary Tract Symptoms	5.4%
545	Hypoxemia	5.4%
546	Urinoma	5.4%
547	Alexia, Pure	5.4%
548	Refsum Disease	5.3%
549	Paraneoplastic Encephalomyelitis	5.3%
550	Carotid Artery Thrombosis	5.2%
551	Postoperative Nausea and Vomiting	5.2%
552	Uveomeningoencephalitic Syndrome	5.2%
553	Myasthenia Gravis, Autoimmune, Experimental	5.2%
554	Sturge-Weber Syndrome	5.2%
555	Alcohol-Induced Disorders, Nervous System	5.2%
556	Body Weight	5.2%
557	Tuberous Sclerosis	5.2%
558	West Nile Fever	5.1%
559	Acromegaly	5.1%
560	Prader-Willi Syndrome	5.1%
561	Eye Hemorrhage	5%
562	Cerebral Amyloid Angiopathy	5%
563	Sinus Thrombosis, Intracranial	5%
564	Menkes Kinky Hair Syndrome	4.9%
565	Hemoptysis	4.9%
566	Ecchymosis	4.9%
567	Petechiae	4.9%
568	Purpura	4.9%
569	Spinal Cord Ischemia	4.8%
570	Metatarsalgia	4.8%
571	Acrodynia	4.8%
572	Dysmenorrhea	4.8%
573	Failed Back Surgery Syndrome	4.8%
574	Tuberculosis, Central Nervous System	4.8%
575	Vascular Remodeling	4.8%
576	Mastodynia	4.7%
577	Breakthrough Pain	4.7%
578	Charcot-Marie-Tooth Disease	4.6%
579	Rett Syndrome	4.5%
580	Brachial Plexus Neuritis	4.5%
581	Neuralgic Amyotrophy	4.5%
582	Cavernous Sinus Thrombosis	4.5%
583	Sagittal Sinus Thrombosis	4.5%
584	Smith-Magenis syndrome	4.5%
585	Dural Arteriovenous Fistula	4.5%
586	Apnea	4.4%
587	Cheyne-Stokes Respiration	4.4%
588	Dyspnea	4.4%
589	Hyperventilation	4.4%
590	Mouth Breathing	4.4%
591	Pruritus	4.4%
592	Sneezing	4.4%
593	Erythema	4.4%
594	Necrolytic Migratory Erythema	4.4%
595	Tachypnea	4.4%
596	Neuritis	4.4%
597	Polyneuritis	4.4%
598	Radiculitis	4.4%
599	Polyneuropathy	4.4%
600	Mononeuritis	4.4%
601	Mononeuropathies	4.4%
602	Brachial Plexus Neuropathies	4.4%
603	Radiculopathy	4.4%
604	Mononeuropathy Multiplex	4.4%
605	Nerve Root Compression	4.4%
606	Hematoma, Subdural, Intracranial	4.4%
607	Hematoma, Subdural, Chronic	4.4%
608	Hematoma, Subdural, Acute	4.4%
609	Edema, Cardiac	4.4%
610	Mental Fatigue	4.4%
611	Hirsutism	4.4%
612	Hypoventilation	4.4%
613	Myalgia	4.4%
614	Body Weight Changes	4.3%
615	Epistaxis	4.3%
616	Amaurosis Fugax	4.3%
617	Blindness, Cortical	4.3%
618	Deafness	4.2%
619	Hearing Loss, Sudden	4.2%
620	Hearing Loss, Bilateral	4.2%
621	Hearing Loss, High-Frequency	4.2%
622	Hearing Loss, Mixed Conductive-Sensorineural	4.2%
623	Hearing Loss, Unilateral	4.2%
624	Complete Hearing Loss	4.2%
625	Deaf Mutism	4.2%
626	Fabry Disease	4.2%
627	Meningocele	4.2%
628	Encephalocele	4.2%
629	Myotonia Congenita	4.2%
630	Low Back Pain	4.2%
631	Visceral Pain	4.2%
632	Neuritis, Autoimmune, Experimental	4.1%
633	Musculoskeletal Pain	4.1%
634	Galactosemias	4.1%
635	Urea Cycle Disorders, Inborn	4.1%
636	Tyrosinemias	4.1%
637	Rubinstein-Taybi Syndrome	4.1%
638	Arthralgia	4.1%
639	Polyarthralgia	4.1%
640	Neuroaspergillosis	4%
641	Waterhouse-Friderichsen Syndrome	4%
642	Nelson Syndrome	3.9%
643	Prolactinoma	3.8%
644	Growth Hormone-Secreting Pituitary Adenoma	3.8%
645	Tarsal Tunnel Syndrome	3.8%
646	Cauda Equina Syndrome	3.8%
647	Myotonic Dystrophy	3.7%
648	Multiple Sclerosis, Chronic Progressive	3.7%
649	Multiple Sclerosis, Relapsing-Remitting	3.7%
650	Homocystinuria	3.7%
651	Pleural Rub	3.7%
652	Rales	3.7%
653	Respiratory Sounds	3.7%
654	Rhonchi	3.7%
655	Stridor	3.7%
656	Wheezing	3.7%
657	Leigh Disease	3.7%
658	Brain Diseases	3.7%
659	Livedo Reticularis	3.7%
660	Oliguria	3.6%
661	Polyuria	3.6%
662	Proteinuria	3.6%
663	Pseudorabies	3.6%
664	Myositis	3.6%
665	Optic Atrophy	3.6%
666	Optic Neuritis	3.6%
667	Papilledema	3.6%
668	Strabismus	3.6%
669	Tolosa-Hunt Syndrome	3.6%
670	Isaacs syndrome	3.6%
671	Arsenic Poisoning	3.6%
672	Myotonic Disorders	3.6%
673	Myasthenic Syndromes, Congenital	3.6%
674	Underweight	3.6%
675	Overweight	3.6%
676	Diabetic Neuropathies	3.6%
677	Facial Injuries	3.6%
678	Facial Neuralgia	3.6%
679	Diabetic Amyotrophy	3.6%
680	Diabetic Autonomic Neuropathy	3.6%
681	Sleep Talking	3.6%
682	Manganese Poisoning	3.6%
683	Sleep Disorders, Intrinsic	3.6%
684	Meningeal Neoplasms	3.5%
685	Meningomyelocele	3.5%
686	Spina Bifida	3.5%
687	Mercury Poisoning, Nervous System	3.5%
688	Lead Poisoning, Nervous System	3.5%
689	Vestibular Neuronitis	3.5%
690	Anterior Spinal Artery Syndrome	3.5%
691	Ascites	3.5%
692	Calculi	3.5%
693	Fibrosis	3.5%
694	Gliosis	3.5%
695	Growth Disorders	3.5%
696	Hemorrhage	3.5%
697	Hernia	3.5%
698	Hyperbilirubinemia	3.5%
699	Hyperplasia	3.5%
700	Hypertrophy	3.5%
701	Hypomenorrhea	3.5%
702	Inflammation	3.5%
703	Intraoperative Complications	3.5%
704	Ischemia	3.5%
705	Lithiasis	3.5%
706	Malacoplakia	3.5%
707	Menstruation Disturbances	3.5%
708	Metaplasia	3.5%
709	Nails, Malformed	3.5%
710	Nerve Degeneration	3.5%
711	Ochronosis	3.5%
712	Polymenorrhea	3.5%
713	polyps	3.5%
714	Postoperative Complications	3.5%
715	Rupture, Spontaneous	3.5%
716	Sclerosis	3.5%
717	Shock	3.5%
718	Ulcer	3.5%
719	Enterocele	3.5%
720	Hyperammonemia	3.5%
721	Hyperamylasemia	3.5%
722	Teratogenesis	3.5%
723	Atheroma	3.5%
724	Cardiac Death	3.5%
725	Hypovolemia	3.5%
726	Hyperuricemia	3.5%
727	Leukoaraiosis	3.5%
728	Stenosis	3.5%
729	Facial asymmetry	3.5%
730	Dysbacteriosis	3.5%
731	Delayed Graft Function	3.5%
732	Cirrhosis	3.5%
733	Plaque, Amyloid	3.5%
734	Plaque, Atherosclerotic	3.5%
735	Neointima	3.5%
736	Dysbiosis	3.5%
737	Neurosyphilis	3.4%
738	Toothache	3.4%
739	Fragile X Syndrome	3.4%
740	Carpal Tunnel Syndrome	3.2%
741	Kearns-Sayre syndrome	3.2%
742	Jaundice, Obstructive	3.2%
743	neurofibroma	3.2%
744	Optic Nerve Glioma	3.2%
745	Gagging	3.2%
746	Hand-Arm Vibration Syndrome	3.1%
747	Alstrom Syndrome	3.1%
748	Fibromyalgia	3.1%
749	Optic Neuropathy, Ischemic	3.1%
750	Anterior Ischemic Optic Neuropathy	3.1%
751	Medial Tibial Stress Syndrome	3.1%
752	Carbamoyl-Phosphate Synthase I Deficiency Disease	3%
753	Facial Hemiatrophy	3%
754	Melkersson-Rosenthal Syndrome	3%
755	Mitochondrial Myopathies	3%
756	Lyme Neuroborreliosis	3%
757	Eosinophilia-Myalgia Syndrome	3%
758	Bulimia	3%
759	Dysuria	3%
760	Fever of Unknown Origin	3%
761	Nocturia	3%
762	Snoring	3%
763	Prostatism	3%
764	Sleep Bruxism	3%
765	Toxoplasmosis, Congenital	3%
766	Anencephaly	3%
767	Acoustic Neuroma	3%
768	Malaria, Cerebral	3%
769	Neurocysticercosis	2.9%
770	Infarction	2.9%
771	Postoperative Hemorrhage	2.9%
772	Shock, Hemorrhagic	2.9%
773	Systemic Inflammatory Response Syndrome	2.9%
774	Incisional hernia	2.9%
775	Cyst	2.9%
776	Extravasation of Diagnostic and Therapeutic Materials	2.9%
777	Neoplastic Processes	2.9%
778	Amyloid Neuropathies, Familial	2.9%
779	Zellweger Syndrome	2.9%
780	Neurobehavioral Manifestations	2.8%
781	Leukoplakia	2.8%
782	Necrosis	2.8%
783	Granulomatosis, Orofacial	2.8%
784	Pigmentation Disorders	2.8%
785	Respiratory Aspiration	2.8%
786	Airway Remodeling	2.8%
787	Angina Pectoris	2.8%
788	Sciatic Neuropathy	2.8%
789	Ulnar Neuropathies	2.8%
790	Lesion of Sciatic Nerve	2.8%
791	Ulnar Neuritis	2.8%
792	Radial nerve compression	2.8%
793	Radial Tunnel Syndrome	2.8%
794	Peroneal Neuropathies	2.8%
795	Radial Neuropathy	2.8%
796	Median Neuropathy	2.8%
797	Sciatic Nerve Palsy	2.8%
798	Femoral Neuropathy	2.8%
799	Tibial Neuropathy	2.8%
800	Ulnar Nerve Palsy	2.8%
801	Postural Orthostatic Tachycardia Syndrome	2.8%
802	Radial nerve palsy	2.8%
803	Acantholysis	2.8%
804	Chromosome Aberrations	2.8%
805	Dehydration	2.8%
806	Granuloma	2.8%
807	Leukocytosis	2.8%
808	Pleocytosis	2.8%
809	Ventricular Remodeling	2.8%
810	Alopecia	2.8%
811	Androgenetic Alopecia	2.8%
812	Glycogen storage disease type II	2.7%
813	Birth Weight	2.7%
814	Hematemesis	2.7%
815	Purpura Fulminans	2.7%
816	Cubital Tunnel Syndrome	2.7%
817	Duane Retraction Syndrome	2.6%
818	Mobius Syndrome	2.6%
819	Bell Palsy	2.6%
820	Herpes Zoster Oticus	2.6%
821	Familial Periodic Paralysis	2.6%
822	Mucopolysaccharidosis II	2.5%
823	Morning Sickness	2.4%
824	Genomic Instability	2.4%
825	Shoulder Pain	2.4%
826	Classical Lissencephalies and Subcortical Band Heterotopias	2.4%
827	Weight Gain	2.4%
828	Diverticulum	2.3%
829	Diverticulosis	2.3%
830	Azotemia	2.3%
831	Thoracic Outlet Syndrome	2.3%
832	Esotropia	2.3%
833	Exotropia	2.3%
834	Hypotension, Orthostatic	2.3%
835	Sleep Apnea Syndromes	2.3%
836	Polymyositis	2.3%
837	Post-Exercise Hypotension	2.3%
838	Disorders of Excessive Somnolence	2.2%
839	Sleep Initiation and Maintenance Disorders	2.2%
840	Night Terrors	2.2%
841	Somnambulism	2.2%
842	Trigeminal Nerve Disorder	2.2%
843	Transient Insomnia	2.2%
844	Sleep Paralysis	2.2%
845	Chronic Insomnia	2.2%
846	REM Sleep Behavior Disorder	2.2%
847	Hypersomnia	2.2%
848	Gaucher Disease	2.2%
849	Dermal Sinus	2.2%
850	Spina Bifida Cystica	2.2%
851	Spina Bifida Occulta	2.2%
852	Meningeal Carcinomatosis	2.2%
853	Lissencephaly	2.2%
854	Polymicrogyria	2.2%
855	Pachygyria	2.2%
856	Schizencephaly	2.2%
857	Lead Poisoning, Nervous System, Childhood	2.2%
858	Lead Poisoning, Nervous System, Adult	2.2%
859	Periventricular Nodular Heterotopia	2.2%
860	Neuronal Ceroid-Lipofuscinoses	2.2%
861	Hydrops Fetalis	2.2%
862	Fetal Weight	2.2%
863	Chromosomal Instability	2.1%
864	Thrombocytopenic purpura	2.1%
865	Fetal Hypoxia	2%
866	Cardiotoxicity	2%
867	Tay-Sachs Disease	2%
868	Aicardi's syndrome	2%
869	Dyspnea, Paroxysmal	2%
870	Purpura, Hyperglobulinemic	2%
871	Urinary Incontinence	2%
872	Brain Damage, Chronic	2%
873	Cockayne Syndrome	2%
874	Albuminuria	2%
875	Hemoglobinuria	2%
876	Polyradiculopathy	2%
877	Alcohol Withdrawal Delirium	2%
878	Eye Injuries	1.9%
879	Niemann-Pick Disease, Type C	1.9%
880	Optic Atrophy, Hereditary, Leber	1.9%
881	Muscular Dystrophy	1.9%
882	Congenital nystagmus	1.9%
883	Orbital Myositis	1.9%
884	Pyomyositis	1.9%
885	Menorrhagia	1.9%
886	Angina, Unstable	1.9%
887	Acute Disease	1.8%
888	Acute-Phase Reaction	1.8%
889	Amenorrhea	1.8%
890	Chronic disease	1.8%
891	Critical Illness	1.8%
892	Sudden death	1.8%
893	Fat necrosis	1.8%
894	Gangrene	1.8%
895	Graft Occlusion, Vascular	1.8%
896	Granuloma, Plasma Cell	1.8%
897	Hematoma	1.8%
898	Diaphragmatic Hernia	1.8%
899	Iatrogenic Disease	1.8%
900	Intestinal Polyps	1.8%
901	Multiple Organ Failure	1.8%
902	Oligomenorrhea	1.8%
903	Premenstrual syndrome	1.8%
904	Recurrence	1.8%
905	Retrograde Degeneration	1.8%
906	Retroperitoneal fibrosis	1.8%
907	Serositis	1.8%
908	Splenomegaly	1.8%
909	Subcutaneous Emphysema	1.8%
910	Surgical Wound Dehiscence	1.8%
911	Syndrome	1.8%
912	Wallerian Degeneration	1.8%
913	Pyogenic granuloma	1.8%
914	Exsanguination	1.8%
915	Disease Progression	1.8%
916	Seroma	1.8%
917	Premenstrual Tension	1.8%
918	Delayed Emergence from Anesthesia	1.8%
919	Infant Death	1.8%
920	Anastomotic Leak	1.8%
921	Intraoperative Awareness	1.8%
922	Holoprosencephaly	1.8%
923	Emaciation	1.8%
924	Neurofibrosarcoma	1.8%
925	Obesity	1.7%
926	POEMS Syndrome	1.6%
927	Meningioma	1.6%
928	Microcephaly	1.6%
929	Macrocephaly	1.6%
930	Hypokalemic periodic paralysis	1.6%
931	Sudden infant death syndrome	1.6%
932	Porencephaly	1.6%
933	Sleep Apnea, Obstructive	1.6%
934	Sleep Apnea, Central	1.6%
935	Persistent Vegetative State	1.6%
936	Narcolepsy	1.6%
937	Trigeminal Neuralgia	1.6%
938	Kleine-Levin Syndrome	1.6%
939	Asphyxia	1.5%
940	Granuloma, Respiratory Tract	1.5%
941	Shock, Traumatic	1.5%
942	Respiratory Tract Fistula	1.5%
943	Tinea Pedis	1.5%
944	Disease susceptibility	1.5%
945	Fetal Death	1.5%
946	Foreign-Body Reaction	1.5%
947	Gastrointestinal Hemorrhage	1.5%
948	Cardiomegaly	1.5%
949	Hemarthrosis	1.5%
950	Hemoperitoneum	1.5%
951	Hemothorax	1.5%
952	Hepatomegaly	1.5%
953	Neoplasm Invasiveness	1.5%
954	Neoplasm Metastasis	1.5%
955	Neoplasm Recurrence, Local	1.5%
956	Parovarian Cyst	1.5%
957	Postpericardiotomy Syndrome	1.5%
958	Prosthesis Failure	1.5%
959	Reperfusion Injury	1.5%
960	Spermatocele	1.5%
961	Oral Fistula	1.5%
962	Injection Site Reaction	1.5%
963	Retrobulbar Hemorrhage	1.5%
964	Cutaneous Fistula	1.5%
965	Aseptic Necrosis of Bone	1.5%
966	Peritoneal Fibrosis	1.5%
967	Carcinogenesis	1.5%
968	Perinatal death	1.5%
969	Infusion site reaction	1.5%
970	Cardiac Hypertrophy	1.5%
971	Nephrogenic Fibrosing Dermopathy	1.5%
972	Corneal Endothelial Cell Loss	1.5%
973	Encapsulating Peritoneal Sclerosis	1.5%
974	Vasoplegia	1.5%
975	Suppuration	1.5%
976	Nephrogenic Systemic Fibrosis	1.5%
977	Metastasis	1.5%
978	Sinus Arrhythmia	1.5%
979	Atrial Fibrillation	1.5%
980	Atrial Flutter	1.5%
981	Dental Pulp Necrosis	1.5%
982	Granuloma, Foreign-Body	1.5%
983	Mediastinal Emphysema	1.5%
984	Surgical Wound Infection	1.5%
985	Ventricular Fibrillation	1.5%
986	Ventricular Flutter	1.5%
987	Parasystole	1.5%
988	Paroxysmal atrial fibrillation	1.5%
989	Facies	1.5%
990	Bradycardia	1.5%
991	Embryo Loss	1.5%
992	Afferent Loop Syndrome	1.4%
993	Sex Chromosome Aberrations	1.4%
994	Short Bowel Syndrome	1.4%
995	Uterine hemorrhage	1.4%
996	Vaginal Fistula	1.4%
997	Rectocele	1.4%
998	No-Reflow Phenomenon	1.4%
999	Hyperemesis Gravidarum	1.4%
1000	Consciousness Disorders	1.4%
1001	Depressed Level of Consciousness	1.4%
1002	Angina Pectoris, Variant	1.4%
1003	Eye Burns	1.3%
1004	Welander Distal Myopathy	1.3%
1005	Cataplexy	1.3%
1006	Drowning	1.3%
1007	Nasal Polyps	1.2%
1008	Fetal Growth Retardation	1.2%
1009	DNA Degradation, Necrotic	1.2%
1010	Aneuploidy	1.2%
1011	Polyploidy	1.2%
1012	Microsatellite Instability	1.2%
1013	Heart Block	1.2%
1014	Tachycardia	1.2%
1015	Tachyarrhythmia	1.2%
1016	Cicatrix	1.2%
1017	Hematuria	1.2%
1018	Urinary Calculi	1.2%
1019	Granuloma Annulare	1.2%
1020	Chromosome Breakage	1.2%
1021	Shock, Cardiogenic	1.2%
1022	Purpura, Thrombotic Thrombocytopenic	1.2%
1023	Urge Incontinence	1.2%
1024	Cachexia	1.2%
1025	Dermatomyositis	1.2%
1026	Corneal Scar	1.2%
1027	Muscular Dystrophy, Duchenne	1.2%
1028	Chromosome Fragility	1.1%
1029	Endotoxic shock	1.1%
1030	Septic Shock	1.1%
1031	Toxic Shock Syndrome	1.1%
1032	Giant Cell Epulis	1.1%
1033	Leukoplakia, Oral	1%
1034	Long QT Syndrome	1%
1035	Micronuclei, Chromosome-Defective	1%
1036	Pediatric Obesity	1%
1037	Sick Sinus Syndrome	1%
1038	Trisomy	1%
1039	Tissue Adhesions	1%
1040	Colonic Polyps	1%
1041	Hematoma, Epidural, Spinal	1%
1042	Autoimmune thrombocytopenia	1%
1043	Immune thrombocytopenic purpura	1%
1044	Corneal Perforation	0.9%
1045	Eosinophilic Granuloma	0.9%
1046	Biliary Fistula	0.8%
1047	Cross Infection	0.8%
1048	Gastric Fistula	0.8%
1049	Hyphema	0.8%
1050	Retinal Neovascularization	0.8%
1051	Septicemia	0.8%
1052	Vitreous Hemorrhage	0.8%
1053	Congenital diaphragmatic hernia	0.8%
1054	Sepsis	0.8%
1055	Abscess	0.8%
1056	Dental Fistula	0.8%
1057	Empyema	0.8%
1058	Femur Head Necrosis	0.8%
1059	Fetal Resorption	0.8%
1060	Lymphatic Metastasis	0.8%
1061	Neoplasms, Unknown Primary	0.8%
1062	Oroantral Fistula	0.8%
1063	Peptic Ulcer Hemorrhage	0.8%
1064	Sudden Cardiac Death	0.8%
1065	Left Ventricular Hypertrophy	0.8%
1066	Leukemic Infiltration	0.8%
1067	Right Ventricular Hypertrophy	0.8%
1068	Premenstrual Dysphoric Disorder	0.8%
1069	Choroidal Neovascularization	0.8%
1070	Primary Graft Dysfunction	0.8%
1071	Neoplasm Micrometastasis	0.8%
1072	Dumping Syndrome	0.8%
1073	Rectal Prolapse	0.8%
1074	Uterine Prolapse	0.8%
1075	Cicatrix, Hypertrophic	0.8%
1076	Vaginal Prolapse	0.8%
1077	Sinus Arrest, Cardiac	0.8%
1078	Metrorrhagia	0.8%
1079	Vesicovaginal Fistula	0.8%
1080	Bronchial Fistula	0.7%
1081	Pancreatic Fistula	0.7%
1082	Retinal Hemorrhage	0.7%
1083	Choroid Hemorrhage	0.7%
1084	Intestinal Fistula	0.7%
1085	Melena	0.7%
1086	Gastroschisis	0.7%
1087	Enterocutaneous Fistula	0.7%
1088	Postpartum Hemorrhage	0.7%
1089	Salivary Gland Fistula	0.7%
1090	Cystocele	0.7%
1091	Gingival Hemorrhage	0.7%
1092	Keloid	0.7%
1093	Monosomy	0.7%
1094	Tetraploidy	0.7%
1095	Stillbirth	0.7%
1096	Adams-Stokes Syndrome	0.7%
1097	Atrioventricular Block	0.7%
1098	Bundle-Branch Block	0.7%
1099	Atrial Premature Complexes	0.7%
1100	Sinoatrial Block	0.7%
1101	Tachycardia, Paroxysmal	0.7%
1102	Supraventricular tachycardia	0.7%
1103	Tachycardia, Ventricular	0.7%
1104	Tachycardia, Reciprocating	0.7%
1105	Hematoma, Subdural, Spinal	0.6%
1106	Cellulitis	0.6%
1107	Romano-Ward Syndrome	0.6%
1108	Granuloma, Laryngeal	0.5%
1109	Myocardial Reperfusion Injury	0.5%
1110	Urinary Bladder Fistula	0.5%
1111	Viremia	0.5%
1112	Parasitemia	0.5%
1113	Umbilical hernia	0.5%
1114	Arteriovenous fistula	0.4%
1115	Philadelphia Chromosome	0.4%
1116	Bacteremia	0.4%
1117	Cell Transformation, Viral	0.4%
1118	Fungemia	0.4%
1119	Kidney Calculi	0.4%
1120	Ureteral Calculi	0.4%
1121	Tachycardia, Atrioventricular Nodal Reentry	0.4%
1122	Tachycardia, Ectopic Atrial	0.4%
1123	Tachycardia, Ectopic Junctional	0.4%
1124	Sinus Tachycardia	0.4%
1125	Torsades de Pointes	0.4%
1126	Accelerated Idioventricular Rhythm	0.4%
1127	Rectal Fistula	0.3%
1128	Anal Fistula	0.3%
1129	Endotoxemia	0.3%
1130	Candidemia	0.2%

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