MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Neoplasms, Multiple Primary

(UMLS:C0027663)

Definition:: Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.
UMLS ID:: C0027663
MeSH ID:: D009378

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.651

Synonym(s)

Neoplasms, Multiple Primary

multiple primary neoplasia

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Amsacrine	7894236	CTD
2	Azacitidine	6209028	CTD
3	Norinyl	48099 170431	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Hamartoma	33.3%
2	Neoplasms, Hormone-Dependent	33.3%
3	Paraneoplastic Syndromes	33.3%
4	Precancerous Conditions	33.3%
5	Neoplasms, Second Primary	33.3%
6	Carcinoma 256, Walker	25.8%
7	Carcinoma, Ehrlich Tumor	25.3%
8	Dermoid Cyst	25.3%
9	Carcinoma, Lewis Lung	25.3%
10	Neoplasms, Neuroepithelial	24.1%
11	Gliomatosis cerebri	24.1%
12	Neuroectodermal Tumors	23.8%
13	Medulloblastoma	23.4%
14	Abdominal Neoplasms	23.1%
15	Erythroplasia	23.1%
16	Follicular cyst	23.1%
17	Head and Neck Neoplasms	23.1%
18	leukemia	23.1%
19	melanoma	23.1%
20	Mucocele	23.1%
21	Neoplasms, Germ Cell and Embryonal	23.1%
22	Neoplasms, Glandular and Epithelial	23.1%
23	Pilonidal Cyst	23.1%
24	Soft Tissue Neoplasms	23.1%
25	Thoracic Neoplasms	23.1%
26	Thyroglossal Cyst	23.1%
27	Synovial Cyst	23.1%
28	Germ Cell Cancer	23.1%
29	Aberrant Crypt Foci	23.1%
30	Carcinosarcoma	22.4%
31	Hemangiosarcoma	22.4%
32	Leukemia L1210	22.4%
33	Leukemia P388	22.4%
34	lymphangiosarcoma	22.4%
35	Acanthoma	22.4%
36	Adenoma, Acidophil	22%
37	Ganglioneuroma	22%
38	Glioma	22%
39	Malignant Glioma	22%
40	Sarcoma 180	21.6%
41	Carcinoid Tumor	21.5%
42	Neurilemmoma	21.5%
43	Hutchinson's Melanotic Freckle	21.5%
44	Melanoma, Amelanotic	21.5%
45	Melanoma, Experimental	21.1%
46	Cyst	21.1%
47	Neoplastic Processes	21.1%
48	Neoplastic Syndromes, Hereditary	21.1%
49	Pregnancy Complications, Neoplastic	21.1%
50	Astrocytoma	21%
51	Ependymoma	21%
52	oligodendroglioma	21%
53	Ganglioglioma	21%
54	gliosarcoma	21%
55	Anaplastic astrocytoma	21%
56	Anaplastic Oligodendroglioma	21%
57	Basal cell carcinoma	20.9%
58	Carcinoma, Papillary	20.9%
59	Squamous cell carcinoma	20.9%
60	Chondrosarcoma	20.9%
61	Craniopharyngioma	20.9%
62	Cystadenoma	20.9%
63	leiomyosarcoma	20.9%
64	liposarcoma	20.9%
65	Mesothelioma	20.9%
66	synovial sarcoma	20.9%
67	Neuroectodermal Tumor, Melanotic	20.9%
68	Angiomyolipoma	20.9%
69	Clear Cell Sarcoma of Soft Tissue	20.9%
70	Alveolar Soft Part Sarcoma	20.9%
71	Neuroendocrine Tumors	20.9%
72	Sarcoma, Myeloid	20.9%
73	Carcinoma, Basal Cell	20.9%
74	Malignant Carcinoid Syndrome	20.8%
75	Neoplasms, Experimental	20.5%
76	Glioblastoma	20.5%
77	Neuroblastoma	20.5%
78	Glioblastoma Multiforme	20.5%
79	Ganglioneuroblastoma	20.3%
80	Cystadenocarcinoma	20.2%
81	Fibrosarcoma	20.2%
82	Osteosarcoma	20.2%
83	Mucoepidermoid Carcinoma	20.2%
84	Paraneoplastic Encephalomyelitis	20%
85	Adenofibroma	19.9%
86	Fibroadenoma	19.9%
87	Malignant Fibrous Histiocytoma	19.9%
88	Trophoblastic Neoplasms	19.6%
89	Bowen's Disease	19.5%
90	Paraganglioma	19.5%
91	Rhabdomyosarcoma	19.5%
92	Giant Cell Tumor of Bone	19.5%
93	Leukemia, Experimental	19.5%
94	Mammary Neoplasms, Experimental	19.5%
95	Meningioma	19.5%
96	Dermatofibrosarcoma	19.2%
97	Dermatofibrosarcoma Protuberans	19.2%
98	Pheochromocytoma	18.9%
99	Alveolar rhabdomyosarcoma	18.9%
100	Choriocarcinoma	18.6%
101	Carcinoma, Lobular	18.6%
102	Adenoma	18.5%
103	Ameloblastoma	18.5%
104	Angiokeratoma	18.5%
105	Carcinoma	18.5%
106	Chordoma	18.5%
107	Hemangioma	18.5%
108	hemangiopericytoma	18.5%
109	Lymphangioma	18.5%
110	Mesenchymoma	18.5%
111	Nevus	18.5%
112	Retroperitoneal Neoplasms	18.5%
113	Teratoma	18.5%
114	Hepatoblastoma	18.5%
115	Mixed Tumor, Mullerian	18.5%
116	Germinoma	18.5%
117	Teratocarcinoma	18.5%
118	Angiofibroma	18.5%
119	Sarcoma	18.5%
120	Epithelioma	18.5%
121	Sarcoma, Experimental	18.4%
122	Thymoma	16.5%
123	Carcinoid Heart Disease	16.5%
124	Leukemia, Plasma Cell	16.4%
125	Adenocarcinoma	16.4%
126	Carcinoma in Situ	16.4%
127	Carcinoma, Transitional Cell	16.4%
128	Phyllodes Tumor	16.4%
129	Dysgerminoma	16.4%
130	Hemangioendothelioma	16.4%
131	Lipoma	16.4%
132	Myoma	16.4%
133	Myxoma	16.4%
134	Neuroma	16.4%
135	Papilloma	16.4%
136	Pseudomyxoma Peritonei	16.4%
137	Seminoma	16.4%
138	Papillomatosis	16.4%
139	Angiolipoma	16.4%
140	Myelolipoma	16.4%
141	Neoplasms, Bone Tissue	16.4%
142	Neoplasms, Fibrous Tissue	16.4%
143	Smooth Muscle Tumor	16.4%
144	Adenomatosis, Pulmonary	16.4%
145	Adenomatous Polyps	16.4%
146	Carcinoma, Large Cell	16.4%
147	Carcinoma, Small Cell	16.4%
148	Desmoplastic Small Round Cell Tumor	16.4%
149	Chondroma	16.4%
150	Enchondroma	16.4%
151	Digestive System Neoplasms	15.8%
152	Endocrine Gland Neoplasms	15.8%
153	Eye Neoplasms	15.8%
154	Nervous System Neoplasms	15.8%
155	Leukemia, Radiation-Induced	15.6%
156	Adenoid Cystic Carcinoma	15.3%
157	fibroma	15.3%
158	Fibromatosis	15.3%
159	Osteoblastoma	15.3%
160	Osteoma	15.3%
161	Rhabdomyoma	15.3%
162	Chondromatosis	15.3%
163	Adenocarcinoma, Clear Cell	15.3%
164	Cholangiocarcinoma	15.3%
165	Cervical Intraepithelial Neoplasia	15.3%
166	Hemangioblastoma	15.3%
167	Lymphoma, Extranodal NK-T-Cell	15.3%
168	Bone neoplasms	15%
169	Leukoplakia	15%
170	Lymphocele	15%
171	Pancreatic Cyst	15%
172	Skin Neoplasms	15%
173	Hematologic Neoplasms	15%
174	Neoplasms, Radiation-Induced	15%
175	Hydatidiform Mole	14.8%
176	Fibromatosis, Aggressive	14.8%
177	Fibromatosis, Abdominal	14.8%
178	Klatskin Tumor	14.8%
179	Retinoblastoma	14.8%
180	Barrett Esophagus	14.6%
181	Breast Cyst	14.6%
182	Histiocytic Disorders, Malignant	14.6%
183	Actinic keratosis	14.6%
184	Mediastinal Cyst	14.6%
185	Neoplasm Invasiveness	14.6%
186	Neoplasm Metastasis	14.6%
187	Neoplasm Recurrence, Local	14.6%
188	Parovarian Cyst	14.6%
189	Pericardial Cyst	14.6%
190	Splenic Neoplasms	14.6%
191	Thymic Cyst	14.6%
192	Carcinogenesis	14.6%
193	Myxoid cyst	14.6%
194	Metastasis	14.6%
195	Carcinoma, Pancreatic Ductal	14.5%
196	Parathyroid Neoplasms	14.3%
197	Peritoneal Neoplasms	14.3%
198	Thyroid Neoplasm	14.3%
199	Thyroid carcinoma	14.3%
200	Acoustic Neuroma	14%
201	Lymphomatoid Granulomatosis	13.9%
202	Neurofibrosarcoma	13.9%
203	Vipoma	13.8%
204	Composite Lymphoma	13.7%
205	Tracheal Neoplasms	13.5%
206	Leukoplakia, Oral	13.1%
207	Multiple Endocrine Neoplasia	13.1%
208	Paraneoplastic Cerebellar Degeneration	13%
209	Basal Cell Nevus Syndrome	12.6%
210	Optic Nerve Glioma	12.4%
211	Endometrial Stromal Sarcoma	12.4%
212	Thyroid Nodule	12.3%
213	Hepatocellular Adenoma	12.3%
214	Mouth Neoplasms	12.2%
215	Central Nervous System Neoplasms	12.2%
216	Vascular Neoplasms	12.2%
217	Thymus Neoplasms	12.2%
218	Lymphangioleiomyomatosis	12.2%
219	Liver Neoplasms, Experimental	12.1%
220	insulinoma	12.1%
221	Gastrinoma	11.9%
222	Glucagonoma	11.9%
223	Genital Neoplasms, Female	11.9%
224	Pancreatic Neoplasm	11.9%
225	Pancreatic Pseudocyst	11.9%
226	Plasmacytoma	11.9%
227	Malignant histiocytosis	11.8%
228	Lymphatic Metastasis	11.8%
229	Neoplasms, Unknown Primary	11.8%
230	Leukemic Infiltration	11.8%
231	Breast Neoplasms, Male	11.8%
232	Histiocytic sarcoma	11.8%
233	Neoplasm Micrometastasis	11.8%
234	Triple Negative Breast Neoplasms	11.8%
235	Nephroblastoma	11.4%
236	Esophageal Neoplasms	10.9%
237	Multiple Endocrine Neoplasia Type 1	10.8%
238	Limbic Encephalitis	10.7%
239	Lymphoma	10.7%
240	Meningeal Neoplasms	10.6%
241	Corpus Luteum Cyst	10.6%
242	Ovarian Cysts	10.6%
243	Leukemia, Myelomonocytic, Chronic	10.5%
244	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	10.5%
245	Leydig Cell Tumor	10.3%
246	Prolactinoma	10.1%
247	Growth Hormone-Secreting Pituitary Adenoma	10.1%
248	Mastocytoma	9.9%
249	Meningeal Carcinomatosis	9.8%
250	Mastocytosis, Systemic	9.8%
251	Leukemia, Myeloid, Chronic-Phase	9.8%
252	Adenomatous Polyposis Coli	9.5%
253	Adrenocortical carcinoma	9.4%
254	Lambert-Eaton Myasthenic Syndrome	9.4%
255	Testicular Neoplasms	9.4%
256	Adrenal Gland Neoplasms	9.1%
257	Gastrointestinal Neoplasms	9.1%
258	Genital Neoplasms, Male	9.1%
259	Liver neoplasms	9.1%
260	Uveal Neoplasms	9.1%
261	Urologic Neoplasms	8.9%
262	Mesoblastic Nephroma	8.8%
263	Sebaceous Gland Neoplasms	8.8%
264	Spinal Neoplasms	8.8%
265	Bone Marrow Neoplasms	8.8%
266	Hodgkin Disease	8.6%
267	Lymphoma, Non-Hodgkin	8.6%
268	Choledochal Cyst	8.6%
269	Polycystic Ovary Syndrome	8.6%
270	granulosa cell tumor	8.6%
271	Carcinoma, Ovarian Epithelial	8.6%
272	Palatal Neoplasms	8.4%
273	Tuberous Sclerosis	8.3%
274	Peutz-Jeghers Syndrome	8.3%
275	Opsoclonus-Myoclonus Syndrome	8.1%
276	Ear Neoplasms	8.1%
277	Eyelid Neoplasms	8.1%
278	Lung Neoplasms	8.1%
279	Pleural Neoplasms	8.1%
280	Renal Cell Carcinoma	8%
281	Papillary Renal Cell Carcinoma	8%
282	Mastocytosis	8%
283	Sturge-Weber Syndrome	8%
284	Cell Transformation, Viral	7.9%
285	Nose Neoplasms	7.9%
286	Carcinoma, Endometrioid	7.9%
287	Brain Neoplasms	7.8%
288	Salivary Gland Neoplasms	7.8%
289	Spinal Cord Neoplasms	7.8%
290	Tongue Neoplasms	7.8%
291	Gastrointestinal Stromal Tumors	7.8%
292	Hemangioma, Cavernous	7.8%
293	Leukemia, T-Cell	7.7%
294	Uterine Neoplasms	7.7%
295	Vaginal Neoplasms	7.7%
296	Vulvar Neoplasms	7.7%
297	Uterine Cancer	7.7%
298	Leukemia, B-Cell	7.7%
299	Fallopian Tube Neoplasms	7.7%
300	neurofibroma	7.7%
301	Lymphoma, Follicular	7.6%
302	T-Cell Lymphoma	7.6%
303	Mantle cell lymphoma	7.6%
304	Bronchial Neoplasms	7.5%
305	Multiple Pulmonary Nodules	7.4%
306	Dupuytren Contracture	7.3%
307	Supratentorial Neoplasms	7.2%
308	Endometrial Neoplasms	7.2%
309	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	7.2%
310	Leukemia, Large Granular Lymphocytic	7.2%
311	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	7.2%
312	Lymphoma, T-Cell, Cutaneous	7.1%
313	Lymphoma, AIDS-Related	7.1%
314	Enteropathy-Associated T-Cell Lymphoma	7.1%
315	Primary Effusion Lymphoma	7.1%
316	Nasopharyngeal carcinoma	7.1%
317	Myelitis, Transverse	7.1%
318	Urticaria Pigmentosa	7.1%
319	Brain Stem Neoplasms	6.9%
320	Mycosis Fungoides	6.9%
321	Lymphomatoid Papulosis	6.9%
322	Plasmablastic lymphoma	6.9%
323	Primary amyloidosis	6.9%
324	Denys-Drash Syndrome	6.8%
325	Choroid Plexus Papilloma	6.8%
326	Pituitary Adenoma	6.8%
327	Pituitary Neoplasms	6.8%
328	Pharyngeal Neoplasms	6.5%
329	Central Nervous System Cysts	6.3%
330	Bile Duct Neoplasms	6.2%
331	gallbladder neoplasm	6.2%
332	Intestinal Neoplasms	6.2%
333	Penile Neoplasms	6.2%
334	Prostatic Neoplasms	6.2%
335	Stomach Neoplasms	6.2%
336	Polycythemia Vera	6.1%
337	Hypopharyngeal Neoplasms	5.8%
338	Pleural Effusion, Malignant	5.8%
339	Hypopharyngeal Cancer	5.8%
340	ovarian neoplasm	5.7%
341	Parotid Neoplasms	5.7%
342	Prostatic Neoplasms, Castration-Resistant	5.7%
343	Nelson Syndrome	5.7%
344	Tonsillar Neoplasms	5.5%
345	Cerebellar Neoplasms	5.5%
346	Laryngeal neoplasm	5.4%
347	Bladder Neoplasm	5.1%
348	Kidney Neoplasm	5.1%
349	Ureteral Neoplasms	5.1%
350	Urethral Neoplasms	5.1%
351	Waldenstrom Macroglobulinemia	4.9%
352	Multiple Myeloma	4.9%
353	Cecal Neoplasms	4.7%
354	Duodenal Neoplasms	4.7%
355	Burkitt Lymphoma	4.7%
356	Sezary Syndrome	4.6%
357	Radicular Cyst	4.6%
358	Xeroderma Pigmentosum	4.6%
359	Appendiceal Neoplasms	4.5%
360	Colonic Neoplasms	4.5%
361	Rectal Neoplasms	4.5%
362	Zollinger-Ellison syndrome	4.2%
363	Nasopharyngeal Neoplasms	4.1%
364	Colorectal Neoplasms	4%
365	Anus Neoplasms	3.8%
366	Sigmoid Neoplasms	3.8%
367	Paranasal Sinus Neoplasms	3.6%
368	Maxillary Sinus Neoplasms	3.4%

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