MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Leukemic Infiltration

(UMLS:C0162679)

Definition:: A pathologic change in leukemia in which leukemic cells permeate various organs at any stage of the disease. All types of leukemia show various degrees of infiltration, depending upon the type of leukemia. The degree of infiltration may vary from site to site. The liver and spleen are common sites of infiltration, the greatest appearing in myelocytic leukemia, but infiltration is seen also in the granulocytic and lymphocytic types. The kidney is also a common site and of the gastrointestinal system, the stomach and ileum are commonly involved. In lymphocytic leukemia the skin is often infiltrated. The central nervous system too is a common site.
UMLS ID:: C0162679
MeSH ID:: D017254

Classification 1:

Name:

Neoplasms
MeSH Tree Number(s):: C04.697.645.500

Classification 2:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.550.727.645.500

Synonym(s)

Leukemic Infiltration

Leukaemic infiltration

Leukemic infiltration

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Genistein	22981962	CTD
2	Tetradecanoylphorbol Acetate	22981962	CTD
3	Thalidomide	15953079	CTD
4	daidzein	22981962	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Neoplasm Metastasis	32.8%
2	Neoplasm Recurrence, Local	32.8%
3	Carcinogenesis	32.8%
4	Metastasis	32.8%
5	Lymphatic Metastasis	21.3%
6	Neoplasms, Unknown Primary	21.3%
7	Neoplasm Micrometastasis	21.3%
8	Polydipsia	17.1%
9	Ascites	16.9%
10	Fibrosis	16.9%
11	Gliosis	16.9%
12	Growth Disorders	16.9%
13	Hemorrhage	16.9%
14	Hyperbilirubinemia	16.9%
15	Hyperplasia	16.9%
16	Hypomenorrhea	16.9%
17	Inflammation	16.9%
18	Intraoperative Complications	16.9%
19	Ischemia	16.9%
20	Lithiasis	16.9%
21	Malacoplakia	16.9%
22	Menstruation Disturbances	16.9%
23	Metaplasia	16.9%
24	Nerve Degeneration	16.9%
25	Ochronosis	16.9%
26	Polymenorrhea	16.9%
27	Postoperative Complications	16.9%
28	Sclerosis	16.9%
29	Shock	16.9%
30	Ulcer	16.9%
31	Hyperammonemia	16.9%
32	Hyperamylasemia	16.9%
33	Teratogenesis	16.9%
34	Cardiac Death	16.9%
35	Hypovolemia	16.9%
36	Hyperuricemia	16.9%
37	Leukoaraiosis	16.9%
38	Dysbacteriosis	16.9%
39	Delayed Graft Function	16.9%
40	Cirrhosis	16.9%
41	Neointima	16.9%
42	Dysbiosis	16.9%
43	Infarction	14.9%
44	Postoperative Hemorrhage	14.9%
45	Shock, Hemorrhagic	14.9%
46	Systemic Inflammatory Response Syndrome	14.9%
47	Vascular Remodeling	13.8%
48	Cyst	13.3%
49	Extravasation of Diagnostic and Therapeutic Materials	13.3%
50	Cell Transformation, Viral	12.9%
51	Necrosis	12.8%
52	Granulomatosis, Orofacial	12.8%
53	Pigmentation Disorders	12.8%
54	Respiratory Aspiration	12.8%
55	Acantholysis	12.6%
56	Chromosome Aberrations	12.6%
57	Dehydration	12.6%
58	Granuloma	12.6%
59	Leukocytosis	12.6%
60	Pleocytosis	12.6%
61	Hamartoma	11.8%
62	Neoplasms, Hormone-Dependent	11.8%
63	Neoplasms, Multiple Primary	11.8%
64	Paraneoplastic Syndromes	11.8%
65	Precancerous Conditions	11.8%
66	Neoplasms, Second Primary	11.8%
67	Signs and Symptoms	10.6%
68	Pathological Conditions, Anatomical	10.6%
69	Genomic Instability	10.5%
70	Chromosomal Instability	10%
71	Incisional hernia	9.9%
72	jaundice	9.9%
73	Azotemia	9.9%
74	Acute Disease	9.9%
75	Acute-Phase Reaction	9.9%
76	Amenorrhea	9.9%
77	Chronic disease	9.9%
78	Critical Illness	9.9%
79	Sudden death	9.9%
80	Fat necrosis	9.9%
81	Gangrene	9.9%
82	Graft Occlusion, Vascular	9.9%
83	Granuloma, Plasma Cell	9.9%
84	Hematoma	9.9%
85	Iatrogenic Disease	9.9%
86	Multiple Organ Failure	9.9%
87	Oligomenorrhea	9.9%
88	Premenstrual syndrome	9.9%
89	Recurrence	9.9%
90	Retrograde Degeneration	9.9%
91	Retroperitoneal fibrosis	9.9%
92	Serositis	9.9%
93	Subcutaneous Emphysema	9.9%
94	Surgical Wound Dehiscence	9.9%
95	Syndrome	9.9%
96	Wallerian Degeneration	9.9%
97	Pyogenic granuloma	9.9%
98	Exsanguination	9.9%
99	Disease Progression	9.9%
100	Seroma	9.9%
101	Premenstrual Tension	9.9%
102	Delayed Emergence from Anesthesia	9.9%
103	Infant Death	9.9%
104	Anastomotic Leak	9.9%
105	Intraoperative Awareness	9.9%
106	Menorrhagia	9.8%
107	Sudden infant death syndrome	9.8%
108	Muscle Weakness	9.6%
109	Leukoplakia	9.4%
110	Pain, Postoperative	9%
111	Neoplastic Syndromes, Hereditary	8.8%
112	Pregnancy Complications, Neoplastic	8.8%
113	Neoplasms, Experimental	8.7%
114	Dysmenorrhea	8.6%
115	Failed Back Surgery Syndrome	8.6%
116	Cardiotoxicity	8.5%
117	Postoperative Nausea and Vomiting	8.5%
118	Eye Hemorrhage	8.3%
119	Hemoptysis	8.1%
120	Ecchymosis	7.9%
121	Petechiae	7.9%
122	Purpura	7.9%
123	Asphyxia	7.8%
124	Granuloma, Respiratory Tract	7.8%
125	Shock, Traumatic	7.8%
126	Multiple Endocrine Neoplasia	7.8%
127	Carcinoma 256, Walker	7.6%
128	Disease susceptibility	7.6%
129	Fetal Death	7.6%
130	Foreign-Body Reaction	7.6%
131	Gastrointestinal Hemorrhage	7.6%
132	Hemarthrosis	7.6%
133	Hemoperitoneum	7.6%
134	Hemothorax	7.6%
135	Parovarian Cyst	7.6%
136	Postpericardiotomy Syndrome	7.6%
137	Prosthesis Failure	7.6%
138	Reperfusion Injury	7.6%
139	Injection Site Reaction	7.6%
140	Retrobulbar Hemorrhage	7.6%
141	Aseptic Necrosis of Bone	7.6%
142	Peritoneal Fibrosis	7.6%
143	Neurogenic Inflammation	7.6%
144	Perinatal death	7.6%
145	Infusion site reaction	7.6%
146	Nephrogenic Fibrosing Dermopathy	7.6%
147	Corneal Endothelial Cell Loss	7.6%
148	Encapsulating Peritoneal Sclerosis	7.6%
149	Vasoplegia	7.6%
150	Suppuration	7.6%
151	Nephrogenic Systemic Fibrosis	7.6%
152	Carcinoma, Ehrlich Tumor	7.5%
153	Dermoid Cyst	7.5%
154	Carcinoma, Lewis Lung	7.5%
155	Sinus Arrhythmia	7.4%
156	Atrial Fibrillation	7.4%
157	Atrial Flutter	7.4%
158	Dental Pulp Necrosis	7.4%
159	Granuloma, Foreign-Body	7.4%
160	Mediastinal Emphysema	7.4%
161	Surgical Wound Infection	7.4%
162	Ventricular Fibrillation	7.4%
163	Ventricular Flutter	7.4%
164	Parasystole	7.4%
165	Paroxysmal atrial fibrillation	7.4%
166	Facies	7.4%
167	Bradycardia	7.4%
168	Embryo Loss	7.4%
169	Afferent Loop Syndrome	7.4%
170	Sex Chromosome Aberrations	7.4%
171	Short Bowel Syndrome	7.4%
172	Uterine hemorrhage	7.4%
173	No-Reflow Phenomenon	7.4%
174	Neoplasms, Radiation-Induced	6.9%
175	Endotoxic shock	6.8%
176	Septic Shock	6.8%
177	Toxic Shock Syndrome	6.8%
178	Paraneoplastic Encephalomyelitis	6.8%
179	Epistaxis	6.8%
180	Abdominal Neoplasms	6.7%
181	Erythroplasia	6.7%
182	Follicular cyst	6.7%
183	Head and Neck Neoplasms	6.7%
184	leukemia	6.7%
185	Mucocele	6.7%
186	Neoplasms, Germ Cell and Embryonal	6.7%
187	Neoplasms, Glandular and Epithelial	6.7%
188	Pilonidal Cyst	6.7%
189	Soft Tissue Neoplasms	6.7%
190	Thoracic Neoplasms	6.7%
191	Thyroglossal Cyst	6.7%
192	Synovial Cyst	6.7%
193	Germ Cell Cancer	6.7%
194	Aberrant Crypt Foci	6.7%
195	Trophoblastic Neoplasms	6.7%
196	Leukemia, Experimental	6.7%
197	Mammary Neoplasms, Experimental	6.7%
198	Neuroectodermal Tumors	6.6%
199	Neoplasms, Neuroepithelial	6.5%
200	Gliomatosis cerebri	6.5%
201	Tissue Adhesions	6.5%
202	Hematoma, Epidural, Spinal	6.5%
203	Chromosome Fragility	6.5%
204	Jaundice, Obstructive	6.5%
205	Melanoma, Experimental	6.3%
206	Drowning	6.2%
207	Fetal Growth Retardation	6%
208	DNA Degradation, Necrotic	6%
209	Aneuploidy	6%
210	Polyploidy	6%
211	Microsatellite Instability	6%
212	Heart Block	6%
213	Sarcoma, Experimental	6%
214	Tachycardia	6%
215	Tachyarrhythmia	6%
216	Cicatrix	6%
217	Hematuria	5.9%
218	Granuloma Annulare	5.9%
219	Chromosome Breakage	5.9%
220	Brain Death	5.9%
221	Shock, Cardiogenic	5.9%
222	melanoma	5.8%
223	Carcinosarcoma	5.7%
224	Hemangiosarcoma	5.7%
225	Leukemia L1210	5.7%
226	Leukemia P388	5.7%
227	lymphangiosarcoma	5.7%
228	Acanthoma	5.7%
229	Meningioma	5.7%
230	Asthenia	5.6%
231	Body Temperature Changes	5.6%
232	Calculi	5.6%
233	Cyanosis	5.6%
234	Edema	5.6%
235	Failure to Thrive	5.6%
236	Fatigue	5.6%
237	Feminization	5.6%
238	Fetal Distress	5.6%
239	Hernia	5.6%
240	Hypertrophy	5.6%
241	Leukemia, Radiation-Induced	5.6%
242	Motion Sickness	5.6%
243	Nails, Malformed	5.6%
244	polyps	5.6%
245	Rupture, Spontaneous	5.6%
246	Signs and Symptoms, Digestive	5.6%
247	Signs and Symptoms, Respiratory	5.6%
248	Skin Manifestations	5.6%
249	Chills	5.6%
250	Lassitude	5.6%
251	Enterocele	5.6%
252	Atheroma	5.6%
253	Pseudophakia	5.6%
254	Urological Manifestations	5.6%
255	Stenosis	5.6%
256	Facial asymmetry	5.6%
257	Mobility Limitation	5.6%
258	Somnolence	5.6%
259	Plaque, Amyloid	5.6%
260	Plaque, Atherosclerotic	5.6%
261	Medulloblastoma	5.6%
262	Sick Sinus Syndrome	5.6%
263	Trisomy	5.6%
264	Tuberous Sclerosis	5.5%
265	Leukoplakia, Oral	5.5%
266	Digestive System Neoplasms	5.3%
267	Endocrine Gland Neoplasms	5.3%
268	Eye Neoplasms	5.3%
269	Nervous System Neoplasms	5.3%
270	Sarcoma 180	5.3%
271	Hematemesis	5.2%
272	Purpura Fulminans	5.2%
273	Multiple Endocrine Neoplasia Type 1	5.2%
274	Adenoma, Acidophil	5.2%
275	Ganglioneuroma	5.2%
276	Glioma	5.2%
277	Malignant Glioma	5.2%
278	Choriocarcinoma	5.1%
279	Carcinoma, Lobular	5.1%
280	Bone neoplasms	5.1%
281	Lymphocele	5.1%
282	Pancreatic Cyst	5.1%
283	Skin Neoplasms	5.1%
284	Hematologic Neoplasms	5.1%
285	Giant Cell Epulis	5.1%
286	Barrett Esophagus	5%
287	Breast Cyst	5%
288	Histiocytic Disorders, Malignant	5%
289	Actinic keratosis	5%
290	Mediastinal Cyst	5%
291	Pericardial Cyst	5%
292	Splenic Neoplasms	5%
293	Thymic Cyst	5%
294	Myxoid cyst	5%
295	Cross Infection	5%
296	Hyphema	5%
297	Retinal Neovascularization	5%
298	Septicemia	5%
299	Vitreous Hemorrhage	5%
300	Sepsis	5%
301	Long QT Syndrome	4.9%
302	Abscess	4.9%
303	Empyema	4.9%
304	Femur Head Necrosis	4.9%
305	Fetal Resorption	4.9%
306	Peptic Ulcer Hemorrhage	4.9%
307	Sudden Cardiac Death	4.9%
308	Premenstrual Dysphoric Disorder	4.9%
309	Choroidal Neovascularization	4.9%
310	Primary Graft Dysfunction	4.9%
311	Basal cell carcinoma	4.9%
312	Carcinoma, Papillary	4.9%
313	Squamous cell carcinoma	4.9%
314	Chondrosarcoma	4.9%
315	Craniopharyngioma	4.9%
316	Cystadenoma	4.9%
317	Dumping Syndrome	4.9%
318	leiomyosarcoma	4.9%
319	liposarcoma	4.9%
320	Mesothelioma	4.9%
321	synovial sarcoma	4.9%
322	Cicatrix, Hypertrophic	4.9%
323	Neuroectodermal Tumor, Melanotic	4.9%
324	Angiomyolipoma	4.9%
325	Clear Cell Sarcoma of Soft Tissue	4.9%
326	Alveolar Soft Part Sarcoma	4.9%
327	Neuroendocrine Tumors	4.9%
328	Sinus Arrest, Cardiac	4.9%
329	Sarcoma, Myeloid	4.9%
330	Carcinoma, Basal Cell	4.9%
331	Micronuclei, Chromosome-Defective	4.9%
332	Hematoma, Subdural, Spinal	4.9%
333	Metrorrhagia	4.9%
334	Hematoma, Subdural	4.8%
335	Hematoma, Epidural, Cranial	4.8%
336	Carcinoid Tumor	4.8%
337	Neurilemmoma	4.8%
338	Hutchinson's Melanotic Freckle	4.8%
339	Melanoma, Amelanotic	4.8%
340	Lymphomatoid Granulomatosis	4.6%
341	Thymoma	4.6%
342	Leukemia, Plasma Cell	4.6%
343	Parathyroid Neoplasms	4.5%
344	Peritoneal Neoplasms	4.5%
345	Thyroid Neoplasm	4.5%
346	Thyroid carcinoma	4.5%
347	Astrocytoma	4.5%
348	Ependymoma	4.5%
349	oligodendroglioma	4.5%
350	Ganglioglioma	4.5%
351	gliosarcoma	4.5%
352	Anaplastic astrocytoma	4.5%
353	Anaplastic Oligodendroglioma	4.5%
354	Cystadenocarcinoma	4.5%
355	Fibrosarcoma	4.5%
356	Osteosarcoma	4.5%
357	Mucoepidermoid Carcinoma	4.5%
358	Eye Manifestations	4.4%
359	Neurologic Manifestations	4.4%
360	Adenoma	4.4%
361	Ameloblastoma	4.4%
362	Angiokeratoma	4.4%
363	Carcinoma	4.4%
364	Chordoma	4.4%
365	Hemangioma	4.4%
366	hemangiopericytoma	4.4%
367	Lymphangioma	4.4%
368	Mesenchymoma	4.4%
369	Nevus	4.4%
370	Retroperitoneal Neoplasms	4.4%
371	Teratoma	4.4%
372	Hepatoblastoma	4.4%
373	Mixed Tumor, Mullerian	4.4%
374	Germinoma	4.4%
375	Teratocarcinoma	4.4%
376	Angiofibroma	4.4%
377	Sarcoma	4.4%
378	Epithelioma	4.4%
379	Composite Lymphoma	4.4%
380	Malignant Carcinoid Syndrome	4.3%
381	Subacute Combined Degeneration	4.3%
382	Cardiac Output, High	4.3%
383	Myocardial Stunning	4.3%
384	Reticulocytosis	4.3%
385	Low Cardiac Output Syndrome	4.3%
386	Airway Remodeling	4.3%
387	Liver Neoplasms, Experimental	4.3%
388	Eosinophilic Granuloma	4.2%
389	Adenofibroma	4.2%
390	Fibroadenoma	4.2%
391	Malignant Fibrous Histiocytoma	4.2%
392	Ventricular Remodeling	4.2%
393	Alopecia	4.2%
394	Intermittent Claudication	4.2%
395	Androgenetic Alopecia	4.2%
396	Phantom pain	4.2%
397	Phantom Limb Pain	4.2%
398	Glioblastoma	4.2%
399	Neuroblastoma	4.2%
400	Glioblastoma Multiforme	4.2%
401	Abdominal Pain	4.1%
402	Nephroblastoma	4.1%
403	Retinal Hemorrhage	4.1%
404	Bowen's Disease	4%
405	Paraganglioma	4%
406	Rhabdomyosarcoma	4%
407	Giant Cell Tumor of Bone	4%
408	Lymphoma	4%
409	Basal Cell Nevus Syndrome	4%
410	Retinoblastoma	4%
411	Choroid Hemorrhage	4%
412	Melena	4%
413	Ganglioneuroblastoma	4%
414	Corpus Luteum Cyst	4%
415	Ovarian Cysts	4%
416	Postpartum Hemorrhage	3.9%
417	Tracheal Neoplasms	3.9%
418	Gingival Hemorrhage	3.9%
419	Keloid	3.9%
420	Monosomy	3.9%
421	Tetraploidy	3.9%
422	Stillbirth	3.9%
423	Pancreatic Neoplasm	3.9%
424	Adams-Stokes Syndrome	3.9%
425	Atrioventricular Block	3.9%
426	Bundle-Branch Block	3.9%
427	Atrial Premature Complexes	3.9%
428	Sinoatrial Block	3.9%
429	Tachycardia, Paroxysmal	3.9%
430	Supraventricular tachycardia	3.9%
431	Tachycardia, Ventricular	3.9%
432	Tachycardia, Reciprocating	3.9%
433	Carcinoma, Pancreatic Ductal	3.9%
434	Subarachnoid Hemorrhage	3.9%
435	Cerebral Hemorrhage	3.9%
436	Viremia	3.9%
437	Parasitemia	3.9%
438	Renal Colic	3.8%
439	Paraneoplastic Cerebellar Degeneration	3.8%
440	Dermatofibrosarcoma	3.8%
441	Dermatofibrosarcoma Protuberans	3.8%
442	Thrombocytopenic purpura	3.8%
443	Kernicterus	3.7%
444	Purpura, Hyperglobulinemic	3.7%
445	Acoustic Neuroma	3.6%
446	Pheochromocytoma	3.6%
447	Alveolar rhabdomyosarcoma	3.6%
448	Hematoma, Subdural, Intracranial	3.6%
449	Hematoma, Subdural, Chronic	3.6%
450	Hematoma, Subdural, Acute	3.6%
451	Hydatidiform Mole	3.5%
452	Endometrial Stromal Sarcoma	3.5%
453	Carcinoid Heart Disease	3.5%
454	Hypergammaglobulinemia	3.4%
455	Choledochal Cyst	3.4%
456	Vipoma	3.4%
457	Mouth Neoplasms	3.4%
458	Central Nervous System Neoplasms	3.4%
459	Vascular Neoplasms	3.4%
460	Thymus Neoplasms	3.4%
461	Cellulitis	3.3%
462	Eye pain	3.3%
463	Diverticulum	3.3%
464	Diverticulosis	3.3%
465	Neurofibrosarcoma	3.3%
466	Genital Neoplasms, Female	3.3%
467	Pancreatic Pseudocyst	3.3%
468	Plasmacytoma	3.3%
469	Esophageal Neoplasms	3.3%
470	Peutz-Jeghers Syndrome	3.3%
471	Anorexia	3.3%
472	Anoxia	3.3%
473	Constipation	3.3%
474	Diarrhea	3.3%
475	Dyspepsia	3.3%
476	Eructation	3.3%
477	Fever	3.3%
478	Flatulence	3.3%
479	Flushing	3.3%
480	Halitosis	3.3%
481	Heartburn	3.3%
482	Diaphragmatic Hernia	3.3%
483	Hiccough	3.3%
484	Hypercalciuria	3.3%
485	Hypercapnia	3.3%
486	Hyperphagia	3.3%
487	Intestinal Polyps	3.3%
488	Nausea	3.3%
489	Pallor	3.3%
490	Psychophysiologic Disorders	3.3%
491	Splenomegaly	3.3%
492	Vomiting	3.3%
493	Hypocapnia	3.3%
494	Dyschezia	3.3%
495	Hypoxia	3.3%
496	Hyperoxia	3.3%
497	Lower Urinary Tract Symptoms	3.3%
498	Hypoxemia	3.3%
499	Urinoma	3.3%
500	Muscular Atrophy	3.3%
501	Malignant histiocytosis	3.3%
502	Thyroid Nodule	3.3%
503	Hepatocellular Adenoma	3.3%
504	Breast Neoplasms, Male	3.3%
505	Histiocytic sarcoma	3.3%
506	Triple Negative Breast Neoplasms	3.3%
507	Limbic Encephalitis	3.3%
508	Adenocarcinoma	3.3%
509	Carcinoma in Situ	3.3%
510	Carcinoma, Transitional Cell	3.3%
511	Phyllodes Tumor	3.3%
512	Dysgerminoma	3.3%
513	Hemangioendothelioma	3.3%
514	Lipoma	3.3%
515	Myoma	3.3%
516	Myxoma	3.3%
517	Neuroma	3.3%
518	Papilloma	3.3%
519	Pseudomyxoma Peritonei	3.3%
520	Seminoma	3.3%
521	Papillomatosis	3.3%
522	Angiolipoma	3.3%
523	Myelolipoma	3.3%
524	Neoplasms, Bone Tissue	3.3%
525	Neoplasms, Fibrous Tissue	3.3%
526	Smooth Muscle Tumor	3.3%
527	Adenomatosis, Pulmonary	3.3%
528	Adenomatous Polyps	3.3%
529	Carcinoma, Large Cell	3.3%
530	Carcinoma, Small Cell	3.3%
531	Desmoplastic Small Round Cell Tumor	3.3%
532	Chondroma	3.3%
533	Enchondroma	3.3%
534	Lymphangioleiomyomatosis	3.2%
535	Romano-Ward Syndrome	3.2%
536	Adenomatous Polyposis Coli	3.2%
537	Optic Nerve Glioma	3.1%
538	insulinoma	3%
539	Bacteremia	3%
540	Fungemia	3%
541	Lambert-Eaton Myasthenic Syndrome	2.9%
542	Testicular Neoplasms	2.9%
543	Gastrinoma	2.9%
544	Glucagonoma	2.9%
545	Granuloma, Laryngeal	2.9%
546	Tachycardia, Atrioventricular Nodal Reentry	2.9%
547	Tachycardia, Ectopic Atrial	2.9%
548	Tachycardia, Ectopic Junctional	2.9%
549	Sinus Tachycardia	2.9%
550	Torsades de Pointes	2.9%
551	Accelerated Idioventricular Rhythm	2.9%
552	Abdomen, Acute	2.8%
553	Myocardial Reperfusion Injury	2.8%
554	Prolactinoma	2.8%
555	Growth Hormone-Secreting Pituitary Adenoma	2.8%
556	Purpura, Thrombotic Thrombocytopenic	2.8%
557	Adrenal Gland Neoplasms	2.7%
558	Gastrointestinal Neoplasms	2.7%
559	Genital Neoplasms, Male	2.7%
560	Liver neoplasms	2.7%
561	Uveal Neoplasms	2.7%
562	Adenoid Cystic Carcinoma	2.7%
563	fibroma	2.7%
564	Fibromatosis	2.7%
565	Osteoblastoma	2.7%
566	Osteoma	2.7%
567	Rhabdomyoma	2.7%
568	Chondromatosis	2.7%
569	Adenocarcinoma, Clear Cell	2.7%
570	Cholangiocarcinoma	2.7%
571	Cervical Intraepithelial Neoplasia	2.7%
572	Hemangioblastoma	2.7%
573	Lymphoma, Extranodal NK-T-Cell	2.7%
574	Urologic Neoplasms	2.7%
575	Sebaceous Gland Neoplasms	2.6%
576	Spinal Neoplasms	2.6%
577	Bone Marrow Neoplasms	2.6%
578	Mesoblastic Nephroma	2.6%
579	Hodgkin Disease	2.6%
580	Lymphoma, Non-Hodgkin	2.6%
581	Respiratory Tract Fistula	2.6%
582	Polycystic Ovary Syndrome	2.6%
583	Opsoclonus-Myoclonus Syndrome	2.6%
584	Leydig Cell Tumor	2.6%
585	Apnea	2.5%
586	Cheyne-Stokes Respiration	2.5%
587	Decerebrate State	2.5%
588	Dyspnea	2.5%
589	Cardiomegaly	2.5%
590	Hemiparesis	2.5%
591	Hepatomegaly	2.5%
592	Hyperventilation	2.5%
593	Meningism	2.5%
594	Mouth Breathing	2.5%
595	Paresis	2.5%
596	Pruritus	2.5%
597	Seizures	2.5%
598	Sensation Disorders	2.5%
599	Sneezing	2.5%
600	Spermatocele	2.5%
601	Erythema	2.5%
602	Oral Fistula	2.5%
603	Complex partial seizures	2.5%
604	Necrolytic Migratory Erythema	2.5%
605	Tachypnea	2.5%
606	Monoparesis	2.5%
607	Cutaneous Fistula	2.5%
608	Gait Disorders, Neurologic	2.5%
609	Neuromuscular Manifestations	2.5%
610	Cardiac Hypertrophy	2.5%
611	Edema, Cardiac	2.5%
612	Mental Fatigue	2.5%
613	Hirsutism	2.5%
614	Orthostatic intolerance	2.5%
615	Hypoventilation	2.5%
616	Meningeal Neoplasms	2.5%
617	Vaginal Fistula	2.5%
618	Rectocele	2.5%
619	Body Weight Changes	2.4%
620	Leukemia, Myelomonocytic, Chronic	2.4%
621	Endotoxemia	2.4%
622	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	2.4%
623	granulosa cell tumor	2.4%
624	Carcinoma, Ovarian Epithelial	2.4%
625	Fibromatosis, Aggressive	2.4%
626	Fibromatosis, Abdominal	2.4%
627	Klatskin Tumor	2.4%
628	Philadelphia Chromosome	2.4%
629	Waterhouse-Friderichsen Syndrome	2.3%
630	Body Weight	2.3%
631	Adrenocortical carcinoma	2.3%
632	Myelitis, Transverse	2.3%
633	Sarcopenia	2.3%
634	Nose Neoplasms	2.3%
635	Palatal Neoplasms	2.2%
636	Primary amyloidosis	2.2%
637	Autoimmune thrombocytopenia	2.2%
638	Immune thrombocytopenic purpura	2.2%
639	Back Pain	2.2%
640	Bulimia	2.2%
641	Neck Pain	2.2%
642	Chest Pain	2.2%
643	Colonic Polyps	2.2%
644	Dizziness	2.2%
645	Dysuria	2.2%
646	Facial Pain	2.2%
647	Fever of Unknown Origin	2.2%
648	Flank Pain	2.2%
649	Headache	2.2%
650	Nocturia	2.2%
651	Pain, Intractable	2.2%
652	Pelvic Pain	2.2%
653	Snoring	2.2%
654	Chronic pain	2.2%
655	Lightheadedness	2.2%
656	Pain, Referred	2.2%
657	Prostatism	2.2%
658	Throbbing Headache	2.2%
659	Labor Pain	2.2%
660	Cancer Pain	2.2%
661	Nociceptive Pain	2.2%
662	Sleep Wake Disorders	2.2%
663	Denys-Drash Syndrome	2.1%
664	Pupil Disorders	2.1%
665	Neurobehavioral Manifestations	2.1%
666	Hoarseness	2.1%
667	Mastocytoma	2%
668	Nasal Polyps	2%
669	Ear Neoplasms	2%
670	Eyelid Neoplasms	2%
671	Lung Neoplasms	2%
672	Pleural Neoplasms	2%
673	Meningeal Carcinomatosis	2%
674	Mastocytosis, Systemic	2%
675	Leukemia, Myeloid, Chronic-Phase	2%
676	Pleural Rub	2%
677	Rales	2%
678	Respiratory Sounds	2%
679	Rhonchi	2%
680	Stridor	2%
681	Wheezing	2%
682	Asterixis	2%
683	Ballismus	2%
684	Renal Cell Carcinoma	2%
685	Papillary Renal Cell Carcinoma	2%
686	Xeroderma Pigmentosum	2%
687	Pituitary Adenoma	2%
688	Pituitary Neoplasms	2%
689	Mastocytosis	2%
690	Sturge-Weber Syndrome	2%
691	Vertigo	2%
692	Pain	2%
693	Livedo Reticularis	2%
694	Ache	2%
695	Brain Neoplasms	2%
696	Meningocele	2%
697	Oliguria	2%
698	Polyuria	2%
699	Proteinuria	2%
700	Salivary Gland Neoplasms	2%
701	Spinal Cord Neoplasms	2%
702	Tongue Neoplasms	2%
703	Urinary Calculi	2%
704	Gastrointestinal Stromal Tumors	2%
705	Encephalocele	2%
706	Hemangioma, Cavernous	2%
707	Leukemia, T-Cell	1.9%
708	Uterine Neoplasms	1.9%
709	Vaginal Neoplasms	1.9%
710	Vulvar Neoplasms	1.9%
711	Uterine Cancer	1.9%
712	Leukemia, B-Cell	1.9%
713	Underweight	1.9%
714	Overweight	1.9%
715	Fallopian Tube Neoplasms	1.9%
716	neurofibroma	1.9%
717	Lymphoma, Follicular	1.9%
718	T-Cell Lymphoma	1.9%
719	Mantle cell lymphoma	1.9%
720	Carcinoma, Endometrioid	1.9%
721	Gait Ataxia	1.9%
722	ovarian neoplasm	1.9%
723	Nasopharyngeal carcinoma	1.9%
724	Basal Ganglia Hemorrhage	1.8%
725	Candidemia	1.7%
726	Voice Disorders	1.7%
727	Voice Disturbance	1.7%
728	Pharyngeal Neoplasms	1.7%
729	Gagging	1.7%
730	Biliary Fistula	1.7%
731	Gastric Fistula	1.7%
732	Congenital diaphragmatic hernia	1.7%
733	Morning Sickness	1.7%
734	Central Nervous System Cysts	1.7%
735	Bronchial Neoplasms	1.7%
736	Bile Duct Neoplasms	1.6%
737	gallbladder neoplasm	1.6%
738	Intestinal Neoplasms	1.6%
739	Penile Neoplasms	1.6%
740	Prostatic Neoplasms	1.6%
741	Stomach Neoplasms	1.6%
742	Waldenstrom Macroglobulinemia	1.6%
743	Multiple Myeloma	1.6%
744	Anosmia	1.6%
745	Ataxia	1.6%
746	Athetosis	1.6%
747	Catalepsy	1.6%
748	Dental Fistula	1.6%
749	Dystonia	1.6%
750	Hemiplegia	1.6%
751	Locked-In Syndrome	1.6%
752	Muscle Hypertonia	1.6%
753	Muscle hypotonia	1.6%
754	Myoclonus	1.6%
755	Myotonia	1.6%
756	Neuralgia	1.6%
757	Oroantral Fistula	1.6%
758	Paraplegia	1.6%
759	Pseudobulbar Palsy	1.6%
760	Quadriplegia	1.6%
761	Spasm	1.6%
762	Spastic Paraplegia	1.6%
763	Status Epilepticus	1.6%
764	Taste Disorders	1.6%
765	Tremor	1.6%
766	Monoplegia	1.6%
767	Hypokinesia	1.6%
768	Left Ventricular Hypertrophy	1.6%
769	Gastroparesis	1.6%
770	Right Ventricular Hypertrophy	1.6%
771	Paraparesis	1.6%
772	Bradykinesia	1.6%
773	Waxy flexibility	1.6%
774	Action Tremor	1.6%
775	Resting Tremor	1.6%
776	Dysosmia	1.6%
777	Quadriparesis	1.6%
778	Olfaction Disorders	1.6%
779	Myokymia	1.6%
780	Multiple Pulmonary Nodules	1.6%
781	Somatosensory Disorders	1.6%
782	Neuropathic pain	1.6%
783	Hyperkinesia	1.6%
784	Intention tremor	1.6%
785	Akathisia	1.6%
786	Restlessness	1.6%
787	Psychomotor Agitation	1.6%
788	Rectal Prolapse	1.6%
789	Uterine Prolapse	1.6%
790	Vaginal Prolapse	1.6%
791	Emaciation	1.6%
792	Low Back Pain	1.6%
793	Polycythemia Vera	1.6%
794	Visceral Pain	1.6%
795	Supratentorial Neoplasms	1.6%
796	Weight Gain	1.6%
797	Endometrial Neoplasms	1.6%
798	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	1.6%
799	Leukemia, Large Granular Lymphocytic	1.6%
800	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	1.6%
801	Vesicovaginal Fistula	1.6%
802	Lymphoma, T-Cell, Cutaneous	1.6%
803	Lymphoma, AIDS-Related	1.6%
804	Enteropathy-Associated T-Cell Lymphoma	1.6%
805	Primary Effusion Lymphoma	1.6%
806	Gait Apraxia	1.5%
807	Dupuytren Contracture	1.5%
808	Putaminal Hemorrhage	1.5%
809	Laryngeal neoplasm	1.5%
810	Urticaria Pigmentosa	1.5%
811	Zollinger-Ellison syndrome	1.5%
812	Brain Stem Neoplasms	1.4%
813	Mycosis Fungoides	1.4%
814	Lymphomatoid Papulosis	1.4%
815	Plasmablastic lymphoma	1.4%
816	Jet Lag Syndrome	1.4%
817	Reflex, Abnormal	1.4%
818	Hyporeflexia	1.4%
819	Hyperreflexia	1.4%
820	Bladder Neoplasm	1.4%
821	Kidney Neoplasm	1.4%
822	Ureteral Neoplasms	1.4%
823	Urethral Neoplasms	1.4%
824	Birth Weight	1.4%
825	Hypopharyngeal Neoplasms	1.4%
826	Vision Disorders	1.4%
827	Pleural Effusion, Malignant	1.4%
828	Hypopharyngeal Cancer	1.4%
829	Metamorphopsia	1.4%
830	Visual Impairment	1.4%
831	Choroid Plexus Papilloma	1.4%
832	Bronchial Fistula	1.4%
833	Metatarsalgia	1.4%
834	Pancreatic Fistula	1.4%
835	Cachexia	1.3%
836	Parotid Neoplasms	1.3%
837	Prostatic Neoplasms, Castration-Resistant	1.3%
838	Nelson Syndrome	1.3%
839	Anisocoria	1.3%
840	Confusion	1.3%
841	Facial paralysis	1.3%
842	Intestinal Fistula	1.3%
843	Lethargy	1.3%
844	Memory Disorders	1.3%
845	Muscle Cramp	1.3%
846	Perceptual Disorders	1.3%
847	Psychomotor Disorders	1.3%
848	Tonic Pupil	1.3%
849	Anhedonia	1.3%
850	Disorientation	1.3%
851	Gastroschisis	1.3%
852	Enterocutaneous Fistula	1.3%
853	Fetal Hypoxia	1.3%
854	Facial Paresis	1.3%
855	Memory Loss	1.3%
856	Hemisensory Neglect	1.3%
857	Dysacusis	1.3%
858	Dyspnea, Paroxysmal	1.3%
859	Mastodynia	1.3%
860	Respiratory Paralysis	1.3%
861	Salivary Gland Fistula	1.3%
862	Chorea	1.3%
863	Cystocele	1.3%
864	Tetany	1.3%
865	Urinary Incontinence	1.3%
866	Breakthrough Pain	1.3%
867	Albuminuria	1.3%
868	Hemoglobinuria	1.3%
869	Umbilical hernia	1.2%
870	Toothache	1.2%
871	Hyperemesis Gravidarum	1.2%
872	Dysgeusia	1.2%
873	Formication	1.2%
874	Hyperalgesia	1.2%
875	Hyperesthesia	1.2%
876	Hypesthesia	1.2%
877	Language Disorders	1.2%
878	Numbness	1.2%
879	Paresthesia	1.2%
880	Paraparesis, Spastic	1.2%
881	Trismus	1.2%
882	Epilepsia Partialis Continua	1.2%
883	Hypogeusia	1.2%
884	Brown-Sequard Syndrome	1.2%
885	Lockjaw	1.2%
886	Allodynia	1.2%
887	Ageusia	1.2%
888	Tonsillar Neoplasms	1.2%
889	Alice in Wonderland Syndrome	1.2%
890	Cerebellar Neoplasms	1.2%
891	Cecal Neoplasms	1.2%
892	Duodenal Neoplasms	1.2%
893	Burkitt Lymphoma	1.2%
894	Alexia	1.1%
895	Dyslexia	1.1%
896	Consciousness Disorders	1.1%
897	Mental Retardation	1.1%
898	Depressed Level of Consciousness	1.1%
899	Mental deficiency	1.1%
900	Intellectual Disability	1.1%
901	Catatonia	1.1%
902	Musculoskeletal Pain	1.1%
903	Ophthalmoplegia	1.1%
904	External Ophthalmoplegia	1.1%
905	Aphonia	1.1%
906	Arthralgia	1.1%
907	Hydrops Fetalis	1.1%
908	Sleep Deprivation	1.1%
909	Polyarthralgia	1.1%
910	Dysphonia	1.1%
911	Cerebrospinal Fluid Otorrhea	1.1%
912	Cerebrospinal Fluid Rhinorrhea	1.1%
913	Fetal Weight	1.1%
914	Obesity	1.1%
915	Sezary Syndrome	1%
916	Radicular Cyst	1%
917	Nasopharyngeal Neoplasms	1%
918	Appendiceal Neoplasms	1%
919	Colonic Neoplasms	1%
920	Rectal Neoplasms	1%
921	Colorectal Neoplasms	1%
922	Agraphia	1%
923	Anomia	1%
924	Cluttering	1%
925	Language Development Disorders	1%
926	Speech Disorders	1%
927	Syncope	1%
928	Stupor	1%
929	Dysgraphia	1%
930	Presyncope	1%
931	Dyslalia	1%
932	Diplopia	1%
933	Muscle Rigidity	1%
934	Muscle Spasticity	1%
935	Scotoma	1%
936	Photophobia	1%
937	Cogwheel Rigidity	1%
938	Hemifacial Spasm	1%
939	Amaurosis	1%
940	Blindness	1%
941	Nuchal Rigidity	1%
942	Angina Pectoris	1%
943	Agnosia	1%
944	Apraxias	1%
945	Hallucinations	1%
946	Hemianopsia	1%
947	Hyperacusis	1%
948	Tinnitus	1%
949	Visual Agnosia	1%
950	Anosognosia	1%
951	Wernicke-Korsakoff Syndrome	1%
952	Phonophobia	1%
953	Hearing Loss	1%
954	Cerebellar Ataxia	1%
955	Torticollis	1%
956	Sciatica	1%
957	Urge Incontinence	1%
958	Tardive Dyskinesia	1%
959	Vocal Cord Paralysis	1%
960	Urinary Bladder Fistula	0.9%
961	Tinea Pedis	0.9%
962	Paranasal Sinus Neoplasms	0.9%
963	Aphasia	0.9%
964	Articulation Disorders	0.9%
965	Echolalia	0.9%
966	Stuttering	0.9%
967	Dysphasia	0.9%
968	Dysarthria	0.9%
969	Anus Neoplasms	0.8%
970	Sigmoid Neoplasms	0.8%
971	Dyskinesia, Drug-Induced	0.8%
972	Amblyopia	0.8%
973	Amnesia	0.8%
974	Delirium	0.8%
975	Horner Syndrome	0.8%
976	Dissociative Amnesia	0.8%
977	Color blindness	0.8%
978	Global Amnesia	0.8%
979	Alcohol Withdrawal Seizures	0.8%
980	Arteriovenous fistula	0.8%
981	Rectal Fistula	0.8%
982	Anal Fistula	0.8%
983	Amaurosis Fugax	0.8%
984	Blindness, Cortical	0.8%
985	Dyscalculia	0.8%
986	Shoulder Pain	0.8%
987	Angina, Unstable	0.8%
988	Maxillary Sinus Neoplasms	0.8%
989	Deafness	0.8%
990	Hearing Loss, Sudden	0.8%
991	Gerstmann Syndrome	0.8%
992	Hearing Loss, Bilateral	0.8%
993	Hearing Loss, High-Frequency	0.8%
994	Hearing Loss, Mixed Conductive-Sensorineural	0.8%
995	Prosopagnosia	0.8%
996	Apraxia, Ideomotor	0.8%
997	Persistent Vegetative State	0.8%
998	Charles Bonnet Syndrome	0.8%
999	Hearing Loss, Unilateral	0.8%
1000	Complete Hearing Loss	0.8%
1001	Alien Hand Syndrome	0.8%
1002	Deaf Mutism	0.8%
1003	Pediatric Obesity	0.8%
1004	Mutism	0.7%
1005	Selective Mutism	0.7%
1006	Angina Pectoris, Variant	0.7%
1007	Akathisia, Drug-Induced	0.7%
1008	Kidney Calculi	0.7%
1009	Ureteral Calculi	0.7%
1010	Myalgia	0.7%
1011	Alexia, Pure	0.7%
1012	Retrograde amnesia	0.7%
1013	Amnesia, Anterograde	0.7%
1014	Auditory Perceptual Disorders	0.6%
1015	Amnesia, Transient Global	0.6%
1016	Ophthalmoplegic Migraine	0.6%
1017	Progressive supranuclear palsy	0.5%
1018	Kearns-Sayre syndrome	0.3%

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