MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Botulism

(UMLS:C0006057)

Definition:: A disease caused by potent protein NEUROTOXINS produced by CLOSTRIDIUM BOTULINUM which interfere with the presynaptic release of ACETYLCHOLINE at the NEUROMUSCULAR JUNCTION. Clinical features include abdominal pain, vomiting, acute PARALYSIS (including respiratory paralysis), blurred vision, and DIPLOPIA. Botulism may be classified into several subtypes (e.g., food-borne, infant, wound, and others). (From Adams et al., Principles of Neurology, 6th ed, p1208)
UMLS ID:: C0006057
MeSH ID:: D001906

Classification 1:

Name:

Bacterial Infections and Mycoses
MeSH Tree Number(s):: C01.252.410.222.151

Classification 2:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.668.758.200|C10.720.150

Classification 3:

Name:

Chemically-Induced Disorders
MeSH Tree Number(s):: C25.723.415.151

Synonym(s)

Botulism

BOTULISM

Botulism due to infection with Clostridium botulinum

Clostridium botulinum intoxication

Clostridium; botulinum

Clostridium; botulinum, poisoning

Infection caused by Clostridium botulinum

Infection due to Clostridium botulinum

Intoxication with Clostridium botulinum toxin

10.

Lame sickness

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Cetirizine	FAERS: 1		US FAERS
2	Docetaxel	FAERS: 1		US FAERS
3	Tobramycin	FAERS: 1		US FAERS
4	Tobramycin	FAERS: 1		US FAERS
5	tofacitinib	FAERS: 1		US FAERS
6	Ascorbic Acid			OFFSIDES
7	Cocaine		16886143	CTD
8	Diltiazem			OFFSIDES
9	Flecainide			OFFSIDES
10	Leucovorin			OFFSIDES
11	Metolazone			OFFSIDES
12	Primidone			OFFSIDES
13	Rabeprazole			OFFSIDES
14	carbidopa, levodopa drug combination			OFFSIDES
15	cyclobenzaprine			OFFSIDES
16	tizanidine			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Neuroleptic Malignant Syndrome	24%
2	Myasthenia Gravis	23.2%
3	MPTP Poisoning	23.1%
4	Motor Neuron Disease	22.9%
5	Arsenic Poisoning	22.6%
6	Mushroom Poisoning	22.3%
7	Dyskinesia, Drug-Induced	22.2%
8	Akathisia, Drug-Induced	21.8%
9	Alcohol-Induced Disorders, Nervous System	21.6%
10	Stiff-Person Syndrome	21.3%
11	Acrodynia	20.6%
12	Heavy Metal Poisoning, Nervous System	20.4%
13	Gas Gangrene	20%
14	Tetanus	20%
15	Lambert-Eaton Myasthenic Syndrome	19.5%
16	Myasthenic Syndromes, Congenital	19.2%
17	Manganese Poisoning	19%
18	Ciguatera Poisoning	18.8%
19	Shellfish Poisoning	18.8%
20	Guillain-Barre Syndrome	18.4%
21	Spinal Muscular Atrophy	18.2%
22	Progressive Muscular Atrophy	18.2%
23	Complex Regional Pain Syndromes	18.1%
24	Causalgia	18%
25	Salmonella food poisoning	18%
26	Polyradiculoneuropathy	17.8%
27	Polyradiculoneuritis	17.8%
28	Amyotrophic Lateral Sclerosis	17.8%
29	Peripheral Nervous System Diseases	17.7%
30	Multiple System Atrophy	17.6%
31	Poliomyelitis	17.5%
32	Mercury Poisoning, Nervous System	17.2%
33	Lead Poisoning, Nervous System	17.2%
34	Neurotoxicity Syndromes	16.4%
35	Miller Fisher Syndrome	16.2%
36	Chronic Fatigue Syndrome	15.7%
37	Alcohol Withdrawal Seizures	15.7%
38	Progressive bulbar palsy	15.6%
39	Bulbar palsy	15.6%
40	Peripheral Nerve Injuries	15.6%
41	Brachial Plexus Neuritis	15.5%
42	Neuralgic Amyotrophy	15.5%
43	Cranial nerve diseases	15.4%
44	Demyelinating Diseases	15.4%
45	Demyelination	15.4%
46	Chronobiology Disorders	15.4%
47	Ophthalmoplegic Migraine	15.3%
48	Myopathy	15.2%
49	Myasthenia Gravis, Autoimmune, Experimental	15.2%
50	Restless Legs Syndrome	15.1%
51	Meningoencephalitis	14.9%
52	Central Nervous System Bacterial Infections	14.6%
53	Meningitis, Listeria	14.4%
54	Tarsal Tunnel Syndrome	14.3%
55	Cauda Equina Syndrome	14.3%
56	Subacute Combined Degeneration	14.2%
57	Enterocolitis, Pseudomembranous	14.2%
58	pseudomembranous colitis	14.2%
59	Actinomycetales Infections	14.1%
60	Listeriosis	14.1%
61	Staphylococcal Infections	14.1%
62	Streptococcal Infections	14.1%
63	Bacillaceae Infections	14.1%
64	Ocular Motility Disorders	14.1%
65	Cyclophoria	14.1%
66	Lead Poisoning, Nervous System, Childhood	14%
67	Lead Poisoning, Nervous System, Adult	14%
68	Parkinson Disease	13.8%
69	Lewy Body Disease	13.7%
70	Striatonigral Degeneration	13.6%
71	Encephalomyelitis	13.6%
72	Prion Diseases	13.6%
73	Autonomic Dysreflexia	13.6%
74	Leukoencephalitis, Acute Hemorrhagic	13.5%
75	Central Nervous System Infection	13.5%
76	Reflex Sympathetic Dystrophy	13.3%
77	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	13.3%
78	Progressive supranuclear palsy	13.2%
79	Trauma, Nervous System	13.2%
80	Tuberculosis, Meningeal	13%
81	Meningitis, Pneumococcal	12.9%
82	Nervous System Neoplasms	12.9%
83	Neurologic Manifestations	12.9%
84	Meningitis, Bacterial	12.9%
85	Myelitis, Transverse	12.7%
86	Dandy-Walker Syndrome	12.6%
87	Pneumocephalus	12.5%
88	Epidural Abscess	12.4%
89	Alcohol Withdrawal Delirium	12.4%
90	Marchiafava-Bignami Disease	12.4%
91	Carpal Tunnel Syndrome	12.3%
92	Fluoride Poisoning	12.2%
93	Gas Poisoning	12.2%
94	Mycotoxicosis	12.2%
95	Plant Poisoning	12.2%
96	Organophosphate poisoning	12.2%
97	Sciatica	12.2%
98	Erysipelothrix infection	12.1%
99	Shy-Drager Syndrome	12.1%
100	Neuritis	12.1%
101	Polyneuritis	12.1%
102	Radiculitis	12.1%
103	Polyneuropathy	12.1%
104	Mononeuritis	12.1%
105	Mononeuropathies	12.1%
106	Brachial Plexus Neuropathies	12.1%
107	Radiculopathy	12.1%
108	Mononeuropathy Multiplex	12.1%
109	Nerve Root Compression	12.1%
110	Neuromyelitis Optica	12.1%
111	Spinal Cord Injuries	11.9%
112	Chemical and Drug Induced Liver Injury	11.8%
113	Olfactory Nerve Injuries	11.6%
114	Impetigo	11.6%
115	Asterixis	11.6%
116	Ballismus	11.6%
117	Opsoclonus-Myoclonus Syndrome	11.6%
118	Brain Abscess	11.3%
119	Cubital Tunnel Syndrome	11.3%
120	Encephalomyelitis, Acute Disseminated	11.2%
121	Myelitis	11.2%
122	Sleep Wake Disorders	11.2%
123	Lyme Neuroborreliosis	11.1%
124	Charcot-Marie-Tooth Disease	11%
125	Leukoencephalopathy, Progressive Multifocal	10.9%
126	Myotonic Dystrophy	10.8%
127	Dystonia Musculorum Deformans	10.8%
128	Neurosyphilis	10.7%
129	Myelinolysis, Central Pontine	10.6%
130	Bites and Stings	10.5%
131	Meningitis, Haemophilus	10.5%
132	Sleep Disorders, Circadian Rhythm	10.4%
133	Facial Nerve Injuries	10.3%
134	Erysipelas	10.3%
135	Staphylococcal Skin Infections	10.3%
136	Psychoses, Substance-Induced	10.3%
137	Lupus Vasculitis, Central Nervous System	10.3%
138	Gram-Negative Bacterial Infections	10.2%
139	Myositis	10.2%
140	Water Intoxication	10.2%
141	Isaacs syndrome	10.2%
142	Myotonic Disorders	10.2%
143	Central Nervous System Cysts	10.1%
144	Borrelia Infections	10.1%
145	Diabetic Neuropathies	10.1%
146	Leptospirosis	10.1%
147	Diabetic Amyotrophy	10.1%
148	Diabetic Autonomic Neuropathy	10.1%
149	Myotonia Congenita	10%
150	Neuralgia	10%
151	Subdural Effusion	10%
152	Meningitis, Fungal	10%
153	Parkinsonian Disorders	10%
154	Nocturnal Myoclonus Syndrome	10%
155	Neuropathic pain	10%
156	Huntington Disease	9.9%
157	Neuritis, Autoimmune, Experimental	9.9%
158	Epilepsy, Post-Traumatic	9.9%
159	Brain Injuries	9.6%
160	Limbic Encephalitis	9.6%
161	Brain Diseases	9.5%
162	Brain Neoplasms	9.5%
163	Dysautonomia	9.5%
164	Meningitis	9.5%
165	Movement Disorders	9.5%
166	Multiple Sclerosis	9.5%
167	Pachymeningitis	9.5%
168	Spinal Cord Diseases	9.5%
169	Spinal Cord Neoplasms	9.5%
170	Vagus Nerve Disorder	9.5%
171	Glossopharyngeal Neuralgia	9.5%
172	Abducens Nerve Diseases	9.5%
173	Tauopathies	9.5%
174	Trochlear Nerve Diseases	9.5%
175	neurofibroma	9.4%
176	Actinomycosis	9.3%
177	Corynebacterium Infections	9.3%
178	Mycobacterium Infections	9.3%
179	Nocardia Infections	9.3%
180	Pneumococcal Infections	9.3%
181	Scarlet Fever	9.3%
182	Sciatic Neuropathy	9.3%
183	Ulnar Neuropathies	9.3%
184	Lesion of Sciatic Nerve	9.3%
185	Pulmonary Nocardiosis	9.3%
186	Ulnar Neuritis	9.3%
187	Radial nerve compression	9.3%
188	Radial Tunnel Syndrome	9.3%
189	Peroneal Neuropathies	9.3%
190	Radial Neuropathy	9.3%
191	Median Neuropathy	9.3%
192	Sciatic Nerve Palsy	9.3%
193	Femoral Neuropathy	9.3%
194	Tibial Neuropathy	9.3%
195	Ulnar Nerve Palsy	9.3%
196	Radial nerve palsy	9.3%
197	Lafora Disease	9.3%
198	Unverricht-Lundborg Syndrome	9.3%
199	Tuberculosis, Central Nervous System	9.2%
200	Ecthyma	9.2%
201	Subacute Bacterial Endocarditis	9.2%
202	Horner Syndrome	9.2%
203	Canavan Disease	9.1%
204	Alexander Disease	9.1%
205	Dementia, Vascular	9.1%
206	Brain Hemorrhage, Traumatic	9%
207	Cerebellar Neoplasms	9%
208	Hand-Arm Vibration Syndrome	9%
209	Erythrasma	8.9%
210	Meige Syndrome	8.8%
211	Cerebral Ventriculitis	8.8%
212	Fibromyalgia	8.8%
213	Medial Tibial Stress Syndrome	8.8%
214	Skin Diseases, Bacterial	8.7%
215	Mitochondrial Myopathies	8.7%
216	Scrapie	8.7%
217	Eosinophilia-Myalgia Syndrome	8.7%
218	Central Cord Syndrome	8.7%
219	Bacteremia	8.6%
220	Presenile dementia	8.6%
221	Senile dementia	8.6%
222	Chorea	8.5%
223	Lyme Disease	8.5%
224	Relapsing Fever	8.5%
225	Central Nervous System Fungal Infections	8.5%
226	Friedreich Ataxia	8.4%
227	Ophthalmoplegia	8.4%
228	Bacterial Vaginosis	8.4%
229	External Ophthalmoplegia	8.4%
230	Neuromuscular Diseases	8.4%
231	Tuberous Sclerosis	8.3%
232	Ataxia Telangiectasia	8.3%
233	Posterior Leukoencephalopathy Syndrome	8.3%
234	Posterior reversible encephalopathy syndrome	8.3%
235	Meningitis, Cryptococcal	8.2%
236	Toxoplasmosis, Cerebral	8.2%
237	Vasculitis, Central Nervous System	8.2%
238	Optic Neuropathy	8.2%
239	Jet Lag Syndrome	8.2%
240	Pyomyositis	8.1%
241	Mitochondrial Encephalomyopathies	8.1%
242	Cadmium poisoning	8.1%
243	Carbon Monoxide Poisoning	8.1%
244	Ergotism	8.1%
245	Lead Poisoning	8.1%
246	Mercury Poisoning	8.1%
247	Refsum Disease	8%
248	Facial Nerve Diseases	8%
249	Craniocerebral Trauma	8%
250	Parasomnia	8%
251	Dyssomnias	8%
252	Polyradiculopathy	8%
253	Mycetoma	7.9%
254	Vestibulocochlear Nerve Diseases	7.9%
255	Decerebrate State	7.9%
256	Hemiparesis	7.9%
257	Hydranencephaly	7.9%
258	Meningism	7.9%
259	Neural Tube Defects	7.9%
260	Paresis	7.9%
261	Seizures	7.9%
262	Sensation Disorders	7.9%
263	Tethered Cord Syndrome	7.9%
264	Central Nervous System Neoplasms	7.9%
265	Complex partial seizures	7.9%
266	Iniencephaly	7.9%
267	Craniorachischisis	7.9%
268	Exencephaly	7.9%
269	Monoparesis	7.9%
270	Septo-Optic Dysplasia	7.9%
271	Cortical Dysplasia	7.9%
272	Neurogenic Inflammation	7.9%
273	Gait Disorders, Neurologic	7.9%
274	Neuromuscular Manifestations	7.9%
275	Malformations of Cortical Development	7.9%
276	Carotid Artery Injuries	7.9%
277	Sweating, Gustatory	7.9%
278	Thoracic Outlet Syndrome	7.9%
279	Auriculotemporal Syndrome	7.9%
280	Brain Death	7.8%
281	Coma, Post-Head Injury	7.8%
282	Polymyositis	7.8%
283	Hepatolenticular Degeneration	7.7%
284	Myoclonic Epilepsy	7.7%
285	Epilepsy, Temporal Lobe	7.7%
286	Epilepsy, Rolandic	7.7%
287	Benign Rolandic Epilepsy	7.7%
288	Bacterial Endocarditis	7.7%
289	Chemical and Drug Induced Liver Injury, Chronic	7.7%
290	Alstrom Syndrome	7.6%
291	Creutzfeldt-Jakob disease	7.6%
292	Basal Ganglia Cerebrovascular Disease	7.6%
293	Syphilis	7.6%
294	Brain Injuries, Diffuse	7.5%
295	Traumatic Brain Injury	7.5%
296	Familial Periodic Paralysis	7.5%
297	Cerebellar Ataxia	7.5%
298	Supratentorial Neoplasms	7.5%
299	Torticollis	7.5%
300	Multiple Sclerosis, Chronic Progressive	7.5%
301	Multiple Sclerosis, Relapsing-Remitting	7.5%
302	Vocal Cord Paralysis	7.5%
303	Amblyopia	7.5%
304	Paraneoplastic Cerebellar Degeneration	7.5%
305	Cerebrospinal Fluid Otorrhea	7.4%
306	Cerebrospinal Fluid Rhinorrhea	7.4%
307	Pituitary Adenoma	7.4%
308	Pituitary Neoplasms	7.4%
309	Gait Ataxia	7.4%
310	Staphylococcal Scalded Skin Syndrome	7.4%
311	Alice in Wonderland Syndrome	7.4%
312	Erythema Chronicum Migrans	7.3%
313	Pneumonia, Bacterial	7.2%
314	Brain Concussion	7.2%
315	Optic Nerve Glioma	7.2%
316	Amyloid Neuropathies, Familial	7.2%
317	Juvenile Myoclonic Epilepsy	7.1%
318	Myoclonic Epilepsies, Progressive	7.1%
319	Vascular Headaches	7.1%
320	Hypoxia-Ischemia, Brain	7.1%
321	Tardive Dyskinesia	7%
322	Persistent Vegetative State	7%
323	Drug toxicity	7%
324	Diphtheria	7%
325	Leprosy	7%
326	Mycobacterium Infections, Nontuberculous	7%
327	Tuberculosis	7%
328	Mycobacterium abscessus Infection	7%
329	Pupil Disorders	7%
330	Neurobehavioral Manifestations	7%
331	Paraneoplastic Encephalomyelitis	6.8%
332	Insect Bites and Stings	6.8%
333	Uveomeningoencephalitic Syndrome	6.8%
334	Muscular Dystrophy	6.7%
335	Rheumatic Fever	6.7%
336	Sturge-Weber Syndrome	6.7%
337	Vertigo	6.7%
338	Orbital Myositis	6.7%
339	Akinetic Mutism	6.7%
340	Anoxic Encephalopathy	6.7%
341	Arachnoiditis	6.7%
342	Basal Ganglia Diseases	6.7%
343	Brain Damage, Chronic	6.7%
344	Cerebellar Diseases	6.7%
345	Encephalitis	6.7%
346	Encephalomalacia	6.7%
347	Epilepsy	6.7%
348	Hydrocephalus	6.7%
349	Congenital Hydrocephalus	6.7%
350	Hypothalamic Diseases	6.7%
351	Aseptic Meningitis	6.7%
352	Syringomyelia	6.7%
353	Thalamic Diseases	6.7%
354	Intracranial Hypertension	6.7%
355	Aura	6.7%
356	Leukoencephalopathy	6.7%
357	Essential Tremor	6.7%
358	Neuroaxonal Dystrophies	6.7%
359	Familial Tremor	6.7%
360	Headache Disorders	6.7%
361	Intracranial Hypotension	6.7%
362	Brain Edema	6.7%
363	Brain Hypoxia	6.7%
364	Aqueductal Stenosis	6.7%
365	Pneumorrhachis	6.7%
366	Writer's Cramp	6.7%
367	Argyria	6.7%
368	Neuroaspergillosis	6.7%
369	Basal Ganglia Hemorrhage	6.7%
370	Myalgia	6.7%
371	Leukomalacia, Periventricular	6.6%
372	Human Ehrlichiosis	6.6%
373	Furunculosis	6.6%
374	furuncle	6.6%
375	Akathisia	6.6%
376	Restlessness	6.6%
377	Psychomotor Agitation	6.6%
378	Diffuse Axonal Injury	6.6%
379	Brain Stem Neoplasms	6.5%
380	MELAS Syndrome	6.5%
381	Neurofibrosarcoma	6.5%
382	Mycoses	6.3%
383	Infection	6.3%
384	Vertebral Artery Dissection	6.2%
385	Psychoses, Alcoholic	6.2%
386	Putaminal Hemorrhage	6.2%
387	Amnesia, Transient Global	6.2%
388	Chlamydia Infections	6.2%
389	Gonorrhea	6.2%
390	Subarachnoid Hemorrhage, Traumatic	6.2%
391	Carotid Artery, Internal, Dissection	6.2%
392	Gait Apraxia	6.2%
393	Subacute Sclerosing Panencephalitis	6.2%
394	Frontotemporal dementia	6.1%
395	Infarction, Middle Cerebral Artery	6.1%
396	Infarction, Anterior Cerebral Artery	6.1%
397	Infarction, Posterior Cerebral Artery	6.1%
398	Adrenoleukodystrophy	6.1%
399	Choroid Plexus Papilloma	6.1%
400	Kearns-Sayre syndrome	6%
401	Bordetella Infections	6%
402	Brucellosis	6%
403	Campylobacter infection	6%
404	Enterobacteriaceae Infections	6%
405	Pseudomonas Infections	6%
406	Q Fever	6%
407	Vibrio Infections	6%
408	Helicobacter Infections	6%
409	Neisseriaceae Infections	6%
410	Burkholderia Infections	6%
411	Flavobacteriaceae Infections	6%
412	Moraxellaceae Infections	6%
413	Burkholderia cepacia Infection	6%
414	Voice Disorders	6%
415	Voice Disturbance	6%
416	Drug abuse	6%
417	Substance Dependence	6%
418	Substance-Related Disorders	6%
419	Drug Dependence	6%
420	Smith-Magenis syndrome	5.9%
421	carbuncle	5.9%
422	Rheumatic Heart Disease	5.9%
423	Dural Arteriovenous Fistula	5.9%
424	Human anaplasmosis	5.9%
425	Pituitary Apoplexy	5.8%
426	POEMS Syndrome	5.8%
427	Mycobacterium avium-intracellulare Infection	5.8%
428	Lymph Node Tuberculosis	5.8%
429	Tuberculosis, Miliary	5.8%
430	Tuberculosis, Multidrug-Resistant	5.8%
431	Leprosy, Multibacillary	5.8%
432	Latent Tuberculosis	5.8%
433	Japanese Spotted Fever	5.8%
434	Hypokalemic periodic paralysis	5.8%
435	Brain Contusion	5.7%
436	Brain Infarction	5.7%
437	Welander Distal Myopathy	5.7%
438	Brain Diseases, Metabolic	5.6%
439	Cerebrovascular Disorders	5.6%
440	Optic Atrophy	5.6%
441	Optic Neuritis	5.6%
442	Papilledema	5.6%
443	Strabismus	5.6%
444	Tolosa-Hunt Syndrome	5.6%
445	Cerebrovascular Insufficiency	5.6%
446	Dementia	5.6%
447	Conus Medullaris Syndrome	5.6%
448	Spinal Cord Vascular Diseases	5.6%
449	Facial Injuries	5.6%
450	Facial Neuralgia	5.6%
451	Sleep Talking	5.6%
452	Sleep Disorders, Intrinsic	5.6%
453	Orthostatic intolerance	5.6%
454	Joint Tuberculosis	5.6%
455	Tuberculosis, Osteoarticular	5.6%
456	Bone Tuberculosis	5.6%
457	Anosmia	5.6%
458	Ataxia	5.6%
459	Athetosis	5.6%
460	Catalepsy	5.6%
461	Dystonia	5.6%
462	Hemiplegia	5.6%
463	Locked-In Syndrome	5.6%
464	Meningeal Neoplasms	5.6%
465	Meningomyelocele	5.6%
466	Muscle Hypertonia	5.6%
467	Muscle hypotonia	5.6%
468	Myoclonus	5.6%
469	Myotonia	5.6%
470	Paraplegia	5.6%
471	Pseudobulbar Palsy	5.6%
472	Quadriplegia	5.6%
473	Spasm	5.6%
474	Spastic Paraplegia	5.6%
475	Status Epilepticus	5.6%
476	Taste Disorders	5.6%
477	Tremor	5.6%
478	Spina Bifida	5.6%
479	Monoplegia	5.6%
480	Hypokinesia	5.6%
481	Paraparesis	5.6%
482	Bradykinesia	5.6%
483	Waxy flexibility	5.6%
484	Action Tremor	5.6%
485	Resting Tremor	5.6%
486	Dysosmia	5.6%
487	Quadriparesis	5.6%
488	Olfaction Disorders	5.6%
489	Myokymia	5.6%
490	Vestibular Neuronitis	5.6%
491	Somatosensory Disorders	5.6%
492	Hyperkinesia	5.6%
493	Intention tremor	5.6%
494	Waterhouse-Friderichsen Syndrome	5.5%
495	Neuromuscular Junction Diseases	5.4%
496	Classical Lissencephalies and Subcortical Band Heterotopias	5.4%
497	Cerebral Palsy	5.3%
498	Epilepsies, Partial	5.3%
499	Epilepsy, Generalized	5.3%
500	Pseudotumor Cerebri	5.3%
501	Hypertensive Encephalopathy	5.3%
502	Simple Partial Seizures	5.3%
503	Epilepsy, Reflex	5.3%
504	Postural Orthostatic Tachycardia Syndrome	5.3%
505	Headache Disorders, Primary	5.3%
506	Headache Disorders, Secondary	5.3%
507	Medication overuse headache	5.3%
508	Cerebral Infarction	5.3%
509	Brain Stem Infarctions	5.3%
510	Auditory Perceptual Disorders	5.3%
511	West Nile Fever	5.3%
512	Borderline leprosy	5.2%
513	Leprosy, Lepromatous	5.2%
514	Tuberculoid leprosy	5.2%
515	Extensively Drug-Resistant Tuberculosis	5.2%
516	Reflex, Abnormal	5.2%
517	Hyporeflexia	5.2%
518	Hyperreflexia	5.2%
519	Hidradenitis Suppurativa	5.1%
520	Giant Cell Arteritis	5.1%
521	Temporal Arteritis	5.1%
522	Alexia	5.1%
523	Dyslexia	5.1%
524	Lateral Medullary Syndrome	5.1%
525	Acoustic Neuroma	5.1%
526	Dermatomyositis	5.1%
527	Botulism	5%
528	Tick Paralysis	5%
529	Muscular Dystrophy, Duchenne	5%
530	Moyamoya Disease	4.9%
531	Vision Disorders	4.9%
532	Metamorphopsia	4.9%
533	Visual Impairment	4.9%
534	Tuberculosis, Gastrointestinal	4.9%
535	Optic Neuropathy, Ischemic	4.9%
536	Anterior Ischemic Optic Neuropathy	4.9%
537	Facial Hemiatrophy	4.8%
538	Melkersson-Rosenthal Syndrome	4.8%
539	Anisocoria	4.8%
540	Confusion	4.8%
541	Facial paralysis	4.8%
542	Lethargy	4.8%
543	Memory Disorders	4.8%
544	Muscle Cramp	4.8%
545	Perceptual Disorders	4.8%
546	Psychomotor Disorders	4.8%
547	Tonic Pupil	4.8%
548	Anhedonia	4.8%
549	Disorientation	4.8%
550	Facial Paresis	4.8%
551	Memory Loss	4.8%
552	Hemisensory Neglect	4.8%
553	Dysacusis	4.8%
554	Sleep Bruxism	4.8%
555	Anencephaly	4.8%
556	Meningocele	4.8%
557	Muscular Atrophy	4.8%
558	Respiratory Paralysis	4.8%
559	Encephalocele	4.8%
560	Rhinoscleroma	4.7%
561	Tetany	4.7%
562	Hematoma, Subdural	4.7%
563	Hematoma, Epidural, Cranial	4.7%
564	Post-Traumatic Headache	4.7%
565	Tension Headache	4.7%
566	Epilepsy, Complex Partial	4.7%
567	Migraine Disorders	4.7%
568	Abdominal Migraine	4.7%
569	Status Migrainosus	4.7%
570	Cervicogenic Headache	4.7%
571	Hordeolum	4.6%
572	Pituitary Diseases	4.6%
573	Erythema Induratum	4.6%
574	Bacterial conjunctivitis	4.6%
575	Rocky Mountain Spotted Fever	4.5%
576	Ulcerative stomatitis	4.5%
577	Optic Atrophy, Hereditary, Leber	4.5%
578	Carotid Artery Diseases	4.4%
579	Brain Ischemia	4.4%
580	Esotropia	4.4%
581	Exotropia	4.4%
582	Hypotension, Orthostatic	4.4%
583	Sleep Apnea Syndromes	4.4%
584	Cerebrovascular accident	4.4%
585	Kluver-Bucy Syndrome	4.4%
586	Vasospasm, Intracranial	4.4%
587	Spinal Cord Ischemia	4.4%
588	Intracranial Arterial Diseases	4.4%
589	Post-Exercise Hypotension	4.4%
590	Disorders of Excessive Somnolence	4.4%
591	Sleep Initiation and Maintenance Disorders	4.4%
592	Night Terrors	4.4%
593	Somnambulism	4.4%
594	Trigeminal Nerve Disorder	4.4%
595	Transient Insomnia	4.4%
596	Sleep Paralysis	4.4%
597	Chronic Insomnia	4.4%
598	REM Sleep Behavior Disorder	4.4%
599	Hypersomnia	4.4%
600	Wernicke Encephalopathy	4.4%
601	Dermal Sinus	4.4%
602	Dysgeusia	4.4%
603	Formication	4.4%
604	Hyperalgesia	4.4%
605	Hyperesthesia	4.4%
606	Hypesthesia	4.4%
607	Language Disorders	4.4%
608	Numbness	4.4%
609	Paresthesia	4.4%
610	Paraparesis, Spastic	4.4%
611	Spina Bifida Cystica	4.4%
612	Trismus	4.4%
613	Spina Bifida Occulta	4.4%
614	Epilepsia Partialis Continua	4.4%
615	Hypogeusia	4.4%
616	Meningeal Carcinomatosis	4.4%
617	Brown-Sequard Syndrome	4.4%
618	Lissencephaly	4.4%
619	Polymicrogyria	4.4%
620	Pachygyria	4.4%
621	Schizencephaly	4.4%
622	Lockjaw	4.4%
623	Allodynia	4.4%
624	Periventricular Nodular Heterotopia	4.4%
625	Ageusia	4.4%
626	Lymphogranuloma Venereum	4.3%
627	Pertussis	4.3%
628	Cluster Headache	4.3%
629	Migraine with Aura	4.3%
630	Familial Hemiplegic Migraine	4.3%
631	Chronic Paroxysmal Hemicrania	4.3%
632	SUNCT Syndrome	4.3%
633	Paroxysmal Hemicrania	4.3%
634	Hematoma, Subdural, Intracranial	4.3%
635	Hematoma, Subdural, Chronic	4.3%
636	Hematoma, Subdural, Acute	4.3%
637	Syphilis, Congenital	4.3%
638	Duane Retraction Syndrome	4.3%
639	Consciousness Disorders	4.2%
640	Mental Retardation	4.2%
641	Muscle Weakness	4.2%
642	Depressed Level of Consciousness	4.2%
643	Mental deficiency	4.2%
644	Intellectual Disability	4.2%
645	Tuberculosis, Pulmonary	4.2%
646	Mobius Syndrome	4.2%
647	Bell Palsy	4.2%
648	Catatonia	4.2%
649	Herpes Zoster Oticus	4.2%
650	Aphonia	4.2%
651	Sleep Deprivation	4.2%
652	Dysphonia	4.2%
653	Anticholinergic Syndrome	4.1%
654	Serotonin Syndrome	4.1%
655	Propofol Infusion Syndrome	4.1%
656	Tuberculosis, Spinal	4%
657	Acinetobacter Infections	4%
658	Bacteroides Infections	4%
659	Cholera	4%
660	Escherichia coli Infections	4%
661	Haemophilus Infections	4%
662	Klebsiella Infections	4%
663	Meningococcal Infections	4%
664	Mycoplasma Infections	4%
665	Pasteurella Infections	4%
666	Proteus Infections	4%
667	Rickettsia Infections	4%
668	Salmonella infections	4%
669	Scrub Typhus	4%
670	Serratia Infections	4%
671	Ureaplasma Infections	4%
672	Ophthalmia Neonatorum	4%
673	Trachoma	4%
674	Empty Sella Syndrome	3.9%
675	Hyperpituitarism	3.9%
676	Hypopituitarism	3.9%
677	Hypophysitis	3.9%
678	Eye Injuries	3.9%
679	Dermatomycoses	3.9%
680	Cerebral Arterial Diseases	3.9%
681	Vertebrobasilar Insufficiency	3.9%
682	Anterior Spinal Artery Syndrome	3.9%
683	Basilar Artery Stenosis	3.9%
684	Vertebral Artery Stenosis	3.9%
685	Sleep Apnea, Obstructive	3.9%
686	Sleep Apnea, Central	3.9%
687	Intracranial Hemorrhage, Hypertensive	3.9%
688	Transient Cerebral Ischemia	3.9%
689	Narcolepsy	3.8%
690	Trigeminal Neuralgia	3.8%
691	Kleine-Levin Syndrome	3.8%
692	Congenital nystagmus	3.8%
693	Agraphia	3.8%
694	Anomia	3.8%
695	Cluttering	3.8%
696	Language Development Disorders	3.8%
697	Speech Disorders	3.8%
698	Syncope	3.8%
699	Stupor	3.8%
700	Dysgraphia	3.8%
701	Presyncope	3.8%
702	Dyslalia	3.8%
703	Diplopia	3.8%
704	Muscle Rigidity	3.8%
705	Muscle Spasticity	3.8%
706	Scotoma	3.8%
707	Photophobia	3.8%
708	Cogwheel Rigidity	3.8%
709	Hemifacial Spasm	3.8%
710	Amaurosis	3.8%
711	Blindness	3.8%
712	Nuchal Rigidity	3.8%
713	Reye Syndrome	3.8%
714	Intracranial Embolism and Thrombosis	3.8%
715	Hepatic Encephalopathy	3.8%
716	Agnosia	3.8%
717	Apraxias	3.8%
718	Hallucinations	3.8%
719	Hemianopsia	3.8%
720	Hyperacusis	3.8%
721	Tinnitus	3.8%
722	Visual Agnosia	3.8%
723	Anosognosia	3.8%
724	Wernicke-Korsakoff Syndrome	3.8%
725	Phonophobia	3.8%
726	Hearing Loss	3.8%
727	Sarcopenia	3.8%
728	Neuronal Ceroid-Lipofuscinoses	3.7%
729	Hyperprolactinemia	3.6%
730	Subclavian Steal Syndrome	3.6%
731	Pick Disease of the Brain	3.6%
732	Cataplexy	3.6%
733	Aphasia	3.6%
734	Articulation Disorders	3.6%
735	Echolalia	3.6%
736	Stuttering	3.6%
737	Dysphasia	3.6%
738	Pseudorabies	3.4%
739	Marijuana Abuse	3.4%
740	Opioid-Related Disorders	3.4%
741	Nicotine Dependence	3.4%
742	Opioid abuse	3.4%
743	Phencyclidine Abuse	3.4%
744	Substance Abuse, Intravenous	3.4%
745	Substance Withdrawal Syndrome	3.4%
746	Tobacco Use Disorder	3.4%
747	Alcohol-Related Disorders	3.4%
748	Amphetamine-Related Disorders	3.4%
749	Cocaine-Related Disorders	3.4%
750	Metabolic Side Effects of Drugs and Substances	3.4%
751	Dysarthria	3.4%
752	Aspergillosis	3.4%
753	Candidiasis	3.4%
754	Coccidioidomycosis	3.4%
755	Histoplasmosis	3.4%
756	Paracoccidioidomycosis	3.4%
757	Pelvic Infection	3.4%
758	Wound Infection	3.4%
759	Zygomycosis	3.4%
760	Soft Tissue Infection	3.4%
761	Community-Acquired Infections	3.4%
762	Phaeohyphomycosis	3.4%
763	Pneumocystis Infections	3.4%
764	Injection Site Reaction	3.4%
765	Infusion site reaction	3.4%
766	Aicardi's syndrome	3.4%
767	Drug Overdose	3.4%
768	Hoarseness	3.4%
769	Toxoplasmosis, Congenital	3.3%
770	Amnesia	3.3%
771	Delirium	3.3%
772	Dissociative Amnesia	3.3%
773	Color blindness	3.3%
774	Global Amnesia	3.3%
775	Cockayne Syndrome	3.3%
776	Cri-du-Chat Syndrome	3.3%
777	Down Syndrome	3.3%
778	Eye Burns	3.3%
779	Brain Diseases, Metabolic, Inborn	3.3%
780	Trisomy 21	3.3%
781	Malaria, Cerebral	3.3%
782	Candidiasis, Chronic Mucocutaneous	3.3%
783	Cutaneous Candidiasis	3.3%
784	Meningioma	3.3%
785	Williams Syndrome	3.3%
786	Carotid Stenosis	3.3%
787	Intracranial Aneurysm	3.3%
788	Neurocysticercosis	3.3%
789	Microcephaly	3.3%
790	Macrocephaly	3.3%
791	Amaurosis Fugax	3.3%
792	Blindness, Cortical	3.3%
793	Dyscalculia	3.3%
794	Intracranial Arteriosclerosis	3.3%
795	Cerebral Atherosclerosis	3.3%
796	Rett Syndrome	3.3%
797	Subarachnoid Hemorrhage	3.3%
798	Cerebral Arteriosclerosis	3.3%
799	Cerebral Hemorrhage	3.3%
800	Cerebral Thrombosis	3.3%
801	Intracranial Embolism	3.3%
802	Intracranial Thrombosis	3.3%
803	Deafness	3.3%
804	Hearing Loss, Sudden	3.3%
805	Gerstmann Syndrome	3.3%
806	Hearing Loss, Bilateral	3.3%
807	Hearing Loss, High-Frequency	3.3%
808	Hearing Loss, Mixed Conductive-Sensorineural	3.3%
809	Prosopagnosia	3.3%
810	Apraxia, Ideomotor	3.3%
811	Charles Bonnet Syndrome	3.3%
812	Hearing Loss, Unilateral	3.3%
813	Complete Hearing Loss	3.3%
814	Alien Hand Syndrome	3.3%
815	Deaf Mutism	3.3%
816	Porencephaly	3.3%
817	Panophthalmitis	3.3%
818	Menkes Kinky Hair Syndrome	3.3%
819	Mutism	3.1%
820	Selective Mutism	3.1%
821	Acromegaly	3.1%
822	Cerebral Amyloid Angiopathy	3%
823	Sinus Thrombosis, Intracranial	3%
824	Holoprosencephaly	3%
825	Psittacosis	3%
826	Paratyphoid Fever	3%
827	Plague	3%
828	Typhoid Fever	3%
829	TYPHUS	3%
830	Yersinia pseudotuberculosis Infections	3%
831	Bubonic Plague	3%
832	Neonatal Abstinence Syndrome	3%
833	Prader-Willi Syndrome	3%
834	Corneal Scar	2.9%
835	Alexia, Pure	2.9%
836	AIDS Dementia Complex	2.9%
837	Eye Infection	2.9%
838	Respiratory Tract Infections	2.9%
839	Phantom pain	2.9%
840	Phantom Limb Pain	2.9%
841	Tuberculosis, Renal	2.9%
842	Cavernous Sinus Thrombosis	2.9%
843	Sagittal Sinus Thrombosis	2.9%
844	Candidemia	2.9%
845	Retrograde amnesia	2.9%
846	Amnesia, Anterograde	2.9%
847	Carotid Artery Thrombosis	2.9%
848	Bone Diseases, Infectious	2.9%
849	Otomycosis	2.9%
850	Pregnancy Complications, Infectious	2.9%
851	Skin Diseases, Infectious	2.9%
852	Fungemia	2.9%
853	Dysentery, Bacillary	2.8%
854	Arthritis, Infectious	2.8%
855	Piedra	2.8%
856	Suppuration	2.8%
857	Cross Infection	2.8%
858	Septicemia	2.8%
859	Sepsis	2.8%
860	Kernicterus	2.7%
861	Alcohol-Induced Disorders	2.7%
862	Corneal Perforation	2.7%
863	Fabry Disease	2.7%
864	Blastomycosis	2.7%
865	Salmonella Infections, Animal	2.6%
866	Opportunistic Infections	2.6%
867	Cardiotoxicity	2.6%
868	Nelson Syndrome	2.6%
869	Fragile X Syndrome	2.6%
870	Cellulitis	2.5%
871	Lung Diseases, Fungal	2.5%
872	Urinary tract infection	2.4%
873	Rubinstein-Taybi Syndrome	2.4%
874	Prolactinoma	2.4%
875	Growth Hormone-Secreting Pituitary Adenoma	2.4%
876	Chromoblastomycosis	2.4%
877	Dermatophytosis	2.4%
878	Sporotrichosis	2.4%
879	Tinea	2.4%
880	Tinea Versicolor	2.4%
881	Trichophytosis	2.4%
882	Invasive Pulmonary Aspergillosis	2.4%
883	Hyalohyphomycosis	2.4%
884	Endotoxemia	2.4%
885	Galactosemias	2.3%
886	Urea Cycle Disorders, Inborn	2.3%
887	Tyrosinemias	2.3%
888	Alcohol Use Disorder	2.2%
889	Alcoholic Intoxication	2.2%
890	Heroin Dependence	2.2%
891	Morphine Dependence	2.2%
892	Alcohol abuse	2.2%
893	Sexually Transmitted Diseases	2.2%
894	Homocystinuria	2.1%
895	Leigh Disease	2.1%
896	Mucormycosis	2%
897	Carbamoyl-Phosphate Synthase I Deficiency Disease	1.9%
898	Drug Eruptions	1.9%
899	Binge Drinking	1.9%
900	Mucopolysaccharidosis II	1.9%
901	Glycogen storage disease type II	1.8%
902	Oral candidiasis	1.7%
903	Endophthalmitis	1.7%
904	Peritonitis	1.7%
905	Osteomyelitis	1.7%
906	Periostitis	1.7%
907	Surgical Wound Infection	1.7%
908	Pulmonary Aspergillosis	1.7%
909	Bronchopulmonary Aspergillosis	1.7%
910	Abscess	1.7%
911	Adnexitis	1.7%
912	Cardiomyopathy, Alcoholic	1.7%
913	Empyema	1.7%
914	Pelvic Inflammatory Disease	1.7%
915	Pancreatitis, Alcoholic	1.7%
916	Zellweger Syndrome	1.6%
917	Fusariosis	1.6%
918	Gaucher Disease	1.5%
919	Lemierre Syndrome	1.5%
920	Tay-Sachs Disease	1.5%
921	Asthma, Aspirin-Induced	1.5%
922	Superinfection	1.5%
923	Corneal Ulcer	1.4%
924	Fetal Alcohol Spectrum Disorders	1.4%
925	Tinea Capitis	1.4%
926	Onychomycosis	1.4%
927	Puerperal Infection	1.4%
928	Spondylitis	1.4%
929	Appendicitis	1.4%
930	Bacteriuria	1.4%
931	Pyuria	1.4%
932	Endotoxic shock	1.4%
933	Septic Shock	1.4%
934	Toxic Shock Syndrome	1.4%
935	Acute Generalized Exanthematous Pustulosis	1.4%
936	Candidiasis, Vulvovaginal	1.4%
937	Niemann-Pick Disease, Type C	1.4%
938	Psoas Abscess	1.3%
939	Abdominal Abscess	1.3%
940	Tinea Pedis	1.3%
941	Erythema Nodosum	1.2%
942	Serum Sickness	1.2%
943	Arthritis, Reactive	1.2%
944	Fatty Liver, Alcoholic	1.2%
945	Hepatitis, Alcoholic	1.2%
946	Liver Cirrhosis, Alcoholic	1.2%
947	AIDS-Related Opportunistic Infections	1.1%
948	Diverticulitis	1.1%
949	Toxic Epidermal Necrolysis	1%
950	Stevens-Johnson Syndrome	1%
951	Lung Abscess	1%
952	Diverticulum	1%
953	Diverticulosis	1%
954	Discitis	0.9%
955	Mastoiditis	0.9%
956	Petrositis	0.9%
957	Liver Abscess	0.8%
958	Retropharyngeal Abscess	0.8%
959	Peritonsillar Abscess	0.8%
960	Aspergillosis, Allergic Bronchopulmonary	0.7%
961	Liver Abscess, Amebic	0.5%

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120141