MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Ganglioneuroblastoma

(UMLS:C0206718)

Definition:: A moderately malignant neoplasm composed of primitive neuroectodermal cells dispersed in myxomatous or fibrous stroma intermixed with mature ganglion cells. It may undergo transformation into a neuroblastoma. It arises from the sympathetic trunk or less frequently from the adrenal medulla, cerebral cortex, and other locations. Cervical ganglioneuroblastomas may be associated with HORNER SYNDROME and the tumor may occasionally secrete vasoactive intestinal peptide, resulting in chronic diarrhea.
UMLS ID:: C0206718
MeSH ID:: D018305

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.465.625.600.590.650.550.300|C04.557.470.670.590.650.550.300|C04.557.580.625.600.590.650.550.300

Synonym(s)

Ganglioneuroblastoma

GANGLIONEUROBLASTOMA, MALIGNANT

ganglioneuroblastoma

ganglioneuroblastoma, malignant

ganglioneuroblastomas

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	miglustat	FAERS: 1		US FAERS
2	Phenytoin		6106127	CTD
3	Triamcinolone Acetonide			OFFSIDES
4	Triamcinolone			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Medulloblastoma	35.9%
2	Ganglioneuroma	34.4%
3	Glioma	34.4%
4	Malignant Glioma	34.4%
5	leukemia	29.7%
6	Craniopharyngioma	28.5%
7	Neuroectodermal Tumor, Melanotic	28.5%
8	Neuroendocrine Tumors	28.5%
9	Histiocytic Disorders, Malignant	23.9%
10	melanoma	22.6%
11	Retinoblastoma	22.2%
12	Meningioma	21.8%
13	Adenoma	21.7%
14	Carcinoma	21.7%
15	Epithelioma	21.7%
16	Chordoma	21.5%
17	Teratoma	21.5%
18	Germinoma	21.5%
19	Teratocarcinoma	21.5%
20	Trophoblastic Neoplasms	21.4%
21	Hamartoma	20.3%
22	Neoplasms, Hormone-Dependent	20.3%
23	Neoplasms, Multiple Primary	20.3%
24	Paraneoplastic Syndromes	20.3%
25	Precancerous Conditions	20.3%
26	Neoplasms, Second Primary	20.3%
27	Adenoma, Acidophil	20.2%
28	Lymphoma	20%
29	Neoplasms, Germ Cell and Embryonal	19.8%
30	Germ Cell Cancer	19.8%
31	Neoplasms, Glandular and Epithelial	19.7%
32	Astrocytoma	19%
33	Ependymoma	19%
34	oligodendroglioma	19%
35	Ganglioglioma	19%
36	gliosarcoma	19%
37	Anaplastic astrocytoma	19%
38	Anaplastic Oligodendroglioma	19%
39	Carcinosarcoma	18.2%
40	Hemangiosarcoma	18.2%
41	lymphangiosarcoma	18.2%
42	Basal cell carcinoma	18.1%
43	Carcinoma, Papillary	18.1%
44	Squamous cell carcinoma	18.1%
45	Cystadenoma	18.1%
46	Mesothelioma	18.1%
47	Carcinoma, Basal Cell	18.1%
48	Composite Lymphoma	17.2%
49	Carcinoma, Ehrlich Tumor	17.1%
50	Carcinoma, Lewis Lung	17.1%
51	Dermoid Cyst	17%
52	Leukemia, Experimental	16.8%
53	Carcinoid Tumor	16.7%
54	Neurilemmoma	16.6%
55	Cyst	16.4%
56	Neoplastic Processes	16.4%
57	Neoplastic Syndromes, Hereditary	16.4%
58	Pregnancy Complications, Neoplastic	16.4%
59	Neoplasms, Experimental	16.2%
60	Neuroectodermal Tumors	16.1%
61	Leukemia, Plasma Cell	15.2%
62	Paraganglioma	15.1%
63	Ameloblastoma	14.9%
64	Angiokeratoma	14.9%
65	Hemangioma	14.9%
66	hemangiopericytoma	14.9%
67	Lymphangioma	14.9%
68	Mesenchymoma	14.9%
69	Nevus	14.9%
70	Hepatoblastoma	14.9%
71	Mixed Tumor, Mullerian	14.9%
72	Angiofibroma	14.9%
73	Sarcoma	14.9%
74	Carcinoma 256, Walker	14.6%
75	Leukemia, Radiation-Induced	14.6%
76	Melanoma, Experimental	14.2%
77	Cystadenocarcinoma	13.9%
78	Mucoepidermoid Carcinoma	13.9%
79	Neoplasms, Neuroepithelial	13.6%
80	Gliomatosis cerebri	13.6%
81	Neoplasms, Radiation-Induced	13.6%
82	Acanthoma	13.1%
83	Carcinoma, Lobular	12.9%
84	Multiple Endocrine Neoplasia	12.8%
85	Choriocarcinoma	12.8%
86	Chondrosarcoma	12.4%
87	leiomyosarcoma	12.4%
88	liposarcoma	12.4%
89	synovial sarcoma	12.4%
90	Angiomyolipoma	12.4%
91	Clear Cell Sarcoma of Soft Tissue	12.4%
92	Alveolar Soft Part Sarcoma	12.4%
93	Sarcoma, Myeloid	12.4%
94	Hutchinson's Melanotic Freckle	12.2%
95	Melanoma, Amelanotic	12.2%
96	Plasmacytoma	12%
97	Malignant histiocytosis	12%
98	Histiocytic sarcoma	12%
99	Sarcoma, Experimental	11.8%
100	Thymoma	11.8%
101	Glioblastoma	11.4%
102	Glioblastoma Multiforme	11.4%
103	Adenocarcinoma	11.2%
104	Carcinoma in Situ	11.2%
105	Carcinoma, Transitional Cell	11.2%
106	Papilloma	11.2%
107	Pseudomyxoma Peritonei	11.2%
108	Papillomatosis	11.2%
109	Adenomatosis, Pulmonary	11.2%
110	Adenomatous Polyps	11.2%
111	Carcinoma, Large Cell	11.2%
112	Carcinoma, Small Cell	11.2%
113	Dysgerminoma	11%
114	Neuroma	11%
115	Seminoma	11%
116	Adenofibroma	10.9%
117	Fibroadenoma	10.9%
118	Endometrial Stromal Sarcoma	10.9%
119	Leukemia L1210	10.2%
120	Leukemia P388	10.2%
121	Tuberous Sclerosis	10.2%
122	Paraneoplastic Encephalomyelitis	10.2%
123	Mammary Neoplasms, Experimental	10%
124	Hodgkin Disease	10%
125	Lymphoma, Non-Hodgkin	10%
126	Abdominal Neoplasms	9.9%
127	Erythroplasia	9.9%
128	Follicular cyst	9.9%
129	Head and Neck Neoplasms	9.9%
130	Mucocele	9.9%
131	Pilonidal Cyst	9.9%
132	Soft Tissue Neoplasms	9.9%
133	Thoracic Neoplasms	9.9%
134	Thyroglossal Cyst	9.9%
135	Synovial Cyst	9.9%
136	Aberrant Crypt Foci	9.9%
137	Bowen's Disease	9.8%
138	Nephroblastoma	9.6%
139	Optic Nerve Glioma	9.5%
140	Fibrosarcoma	9.5%
141	Osteosarcoma	9.5%
142	Malignant Carcinoid Syndrome	9.4%
143	Lymphangioleiomyomatosis	8.9%
144	Primary amyloidosis	8.7%
145	Pheochromocytoma	8.5%
146	Digestive System Neoplasms	8.3%
147	Endocrine Gland Neoplasms	8.3%
148	Eye Neoplasms	8.3%
149	Nervous System Neoplasms	8.3%
150	Bone neoplasms	8.1%
151	Leukoplakia	8.1%
152	Lymphocele	8.1%
153	Pancreatic Cyst	8.1%
154	Skin Neoplasms	8.1%
155	Hematologic Neoplasms	8.1%
156	Malignant Fibrous Histiocytoma	8%
157	Hepatocellular Adenoma	8%
158	Lymphomatoid Granulomatosis	8%
159	Basal Cell Nevus Syndrome	8%
160	Barrett Esophagus	8%
161	Breast Cyst	8%
162	Actinic keratosis	8%
163	Mediastinal Cyst	8%
164	Neoplasm Invasiveness	8%
165	Neoplasm Metastasis	8%
166	Neoplasm Recurrence, Local	8%
167	Parovarian Cyst	8%
168	Pericardial Cyst	8%
169	Splenic Neoplasms	8%
170	Thymic Cyst	8%
171	Carcinogenesis	8%
172	Myxoid cyst	8%
173	Metastasis	8%
174	Phyllodes Tumor	7.7%
175	Hemangioendothelioma	7.7%
176	Lipoma	7.7%
177	Myoma	7.7%
178	Myxoma	7.7%
179	Angiolipoma	7.7%
180	Myelolipoma	7.7%
181	Neoplasms, Bone Tissue	7.7%
182	Neoplasms, Fibrous Tissue	7.7%
183	Smooth Muscle Tumor	7.7%
184	Desmoplastic Small Round Cell Tumor	7.7%
185	Chondroma	7.7%
186	Enchondroma	7.7%
187	neurofibroma	7.4%
188	Sarcoma 180	7.3%
189	Mesoblastic Nephroma	7.3%
190	Prolactinoma	7%
191	Growth Hormone-Secreting Pituitary Adenoma	7%
192	Waldenstrom Macroglobulinemia	6.8%
193	Multiple Myeloma	6.8%
194	Rhabdomyosarcoma	6.6%
195	Giant Cell Tumor of Bone	6.6%
196	Corpus Luteum Cyst	6.6%
197	Ovarian Cysts	6.6%
198	Multiple Endocrine Neoplasia Type 1	6.4%
199	Liver Neoplasms, Experimental	6.3%
200	Neurofibrosarcoma	6.2%
201	Carcinoma, Ovarian Epithelial	6.2%
202	Leukemia, Myelomonocytic, Chronic	6.2%
203	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	6.2%
204	Acoustic Neuroma	6.1%
205	Adenoid Cystic Carcinoma	6.1%
206	Adenocarcinoma, Clear Cell	6.1%
207	Cholangiocarcinoma	6.1%
208	Cervical Intraepithelial Neoplasia	6.1%
209	Carcinoma, Pancreatic Ductal	6%
210	Parathyroid Neoplasms	5.9%
211	Peritoneal Neoplasms	5.9%
212	Thyroid Neoplasm	5.9%
213	Thyroid carcinoma	5.9%
214	Choledochal Cyst	5.8%
215	Hydatidiform Mole	5.7%
216	Peutz-Jeghers Syndrome	5.7%
217	Adenomatous Polyposis Coli	5.6%
218	Mastocytosis	5.3%
219	Sturge-Weber Syndrome	5.3%
220	Gastrointestinal Stromal Tumors	5.2%
221	Pancreatic Neoplasm	5.2%
222	Hemangioma, Cavernous	5.2%
223	Dermatofibrosarcoma	5.2%
224	Dermatofibrosarcoma Protuberans	5.2%
225	Leukemia, T-Cell	5.2%
226	Leukemia, B-Cell	5.2%
227	Lymphoma, Follicular	5.1%
228	T-Cell Lymphoma	5.1%
229	Mantle cell lymphoma	5.1%
230	Carcinoid Heart Disease	5.1%
231	Retroperitoneal Neoplasms	5%
232	Nasopharyngeal carcinoma	4.9%
233	Vipoma	4.7%
234	granulosa cell tumor	4.6%
235	Tracheal Neoplasms	4.5%
236	Leukoplakia, Oral	4.4%
237	Paraneoplastic Cerebellar Degeneration	4.4%
238	fibroma	4.1%
239	Fibromatosis	4.1%
240	Osteoblastoma	4.1%
241	Osteoma	4.1%
242	Rhabdomyoma	4.1%
243	Chondromatosis	4.1%
244	Hemangioblastoma	4.1%
245	Lymphoma, Extranodal NK-T-Cell	4.1%
246	Mouth Neoplasms	4.1%
247	Central Nervous System Neoplasms	4.1%
248	Vascular Neoplasms	4.1%
249	Thymus Neoplasms	4.1%
250	Genital Neoplasms, Female	4%
251	Pancreatic Pseudocyst	4%
252	Lymphatic Metastasis	4%
253	Neoplasms, Unknown Primary	4%
254	Leukemic Infiltration	4%
255	Breast Neoplasms, Male	4%
256	Neoplasm Micrometastasis	4%
257	Triple Negative Breast Neoplasms	4%
258	insulinoma	4%
259	Esophageal Neoplasms	3.9%
260	Limbic Encephalitis	3.8%
261	Adrenocortical carcinoma	3.8%
262	Alveolar rhabdomyosarcoma	3.8%
263	Xeroderma Pigmentosum	3.7%
264	Denys-Drash Syndrome	3.6%
265	Klatskin Tumor	3.5%
266	Lambert-Eaton Myasthenic Syndrome	3.5%
267	Testicular Neoplasms	3.5%
268	Adrenal Gland Neoplasms	3.4%
269	Gastrointestinal Neoplasms	3.4%
270	Genital Neoplasms, Male	3.4%
271	Liver neoplasms	3.4%
272	Uveal Neoplasms	3.4%
273	Urologic Neoplasms	3.4%
274	Sebaceous Gland Neoplasms	3.4%
275	Spinal Neoplasms	3.4%
276	Bone Marrow Neoplasms	3.4%
277	Renal Cell Carcinoma	3.3%
278	Papillary Renal Cell Carcinoma	3.3%
279	Mastocytoma	3.3%
280	Mastocytosis, Systemic	3.3%
281	Polycystic Ovary Syndrome	3.3%
282	Leukemia, Myeloid, Chronic-Phase	3.3%
283	Opsoclonus-Myoclonus Syndrome	3.1%
284	Carcinoma, Endometrioid	3.1%
285	Thyroid Nodule	3%
286	Gastrinoma	2.8%
287	Glucagonoma	2.8%
288	Myelitis, Transverse	2.8%
289	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	2.8%
290	Leukemia, Large Granular Lymphocytic	2.8%
291	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	2.8%
292	Lymphoma, T-Cell, Cutaneous	2.8%
293	Lymphoma, AIDS-Related	2.8%
294	Enteropathy-Associated T-Cell Lymphoma	2.8%
295	Primary Effusion Lymphoma	2.8%
296	ovarian neoplasm	2.5%
297	Leydig Cell Tumor	2.5%
298	Neuroblastoma	2.4%
299	Fibromatosis, Aggressive	2.4%
300	Fibromatosis, Abdominal	2.4%
301	Nose Neoplasms	2.2%
302	Burkitt Lymphoma	2.1%
303	Meningeal Neoplasms	2.1%
304	Zollinger-Ellison syndrome	2%
305	Pituitary Adenoma	2%
306	Pituitary Neoplasms	2%
307	Palatal Neoplasms	1.8%
308	Ear Neoplasms	1.8%
309	Eyelid Neoplasms	1.8%
310	Lung Neoplasms	1.8%
311	Pleural Neoplasms	1.8%
312	Cell Transformation, Viral	1.7%
313	Brain Neoplasms	1.7%
314	Salivary Gland Neoplasms	1.7%
315	Spinal Cord Neoplasms	1.7%
316	Tongue Neoplasms	1.7%
317	Uterine Neoplasms	1.7%
318	Vaginal Neoplasms	1.7%
319	Vulvar Neoplasms	1.7%
320	Uterine Cancer	1.7%
321	Fallopian Tube Neoplasms	1.7%
322	Dupuytren Contracture	1.6%
323	Urticaria Pigmentosa	1.6%
324	Mycosis Fungoides	1.6%
325	Lymphomatoid Papulosis	1.6%
326	Plasmablastic lymphoma	1.6%
327	Ganglioneuroblastoma	1.6%
328	Pharyngeal Neoplasms	1.5%
329	Central Nervous System Cysts	1.5%
330	Bile Duct Neoplasms	1.5%
331	gallbladder neoplasm	1.5%
332	Intestinal Neoplasms	1.5%
333	Penile Neoplasms	1.5%
334	Prostatic Neoplasms	1.5%
335	Stomach Neoplasms	1.5%
336	Polycythemia Vera	1.5%
337	Laryngeal neoplasm	1.4%
338	Bladder Neoplasm	1.3%
339	Kidney Neoplasm	1.3%
340	Ureteral Neoplasms	1.3%
341	Urethral Neoplasms	1.3%
342	Sezary Syndrome	1.2%
343	Meningeal Carcinomatosis	1.1%
344	Bronchial Neoplasms	0.9%
345	Multiple Pulmonary Nodules	0.9%
346	Supratentorial Neoplasms	0.9%
347	Endometrial Neoplasms	0.9%
348	Hypopharyngeal Neoplasms	0.8%
349	Pleural Effusion, Malignant	0.8%
350	Hypopharyngeal Cancer	0.8%
351	Parotid Neoplasms	0.8%
352	Prostatic Neoplasms, Castration-Resistant	0.8%
353	Nelson Syndrome	0.8%
354	Cecal Neoplasms	0.7%
355	Duodenal Neoplasms	0.7%
356	Nasopharyngeal Neoplasms	0.6%
357	Colorectal Neoplasms	0.6%
358	Paranasal Sinus Neoplasms	0.6%
359	Brain Stem Neoplasms	0.5%
360	Tonsillar Neoplasms	0.5%
361	Cerebellar Neoplasms	0.5%
362	Radicular Cyst	0.4%
363	Appendiceal Neoplasms	0.4%
364	Colonic Neoplasms	0.4%
365	Rectal Neoplasms	0.4%
366	Choroid Plexus Papilloma	0.3%
367	Maxillary Sinus Neoplasms	0.3%
368	Anus Neoplasms	0.2%
369	Sigmoid Neoplasms	0.2%

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