MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Brain Damage, Chronic

(UMLS:C0006109)

Definition:: A condition characterized by long-standing brain dysfunction or damage, usually of three months duration or longer. Potential etiologies include BRAIN INFARCTION; certain NEURODEGENERATIVE DISORDERS; CRANIOCEREBRAL TRAUMA; ANOXIA, BRAIN; ENCEPHALITIS; certain NEUROTOXICITY SYNDROMES; metabolic disorders (see BRAIN DISEASES, METABOLIC); and other conditions.
UMLS ID:: C0006109
MeSH ID:: D001925

Classification:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.140.140

Synonym(s)

Brain Damage, Chronic

CHRONIC BRAIN SYNDROME

Chronic Brain Damage

Chronic Encephalopathy

Chronic brain syndrome

Chronic brain syndrome, NOS

Chronic encephalopathy

Chronic encephalopathy, NOS

brain chronic syndrome

10.

chronic brain damage

11.

chronic brain syndrome

12.

chronic encephalopathy

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Amphetamine	16160707	CTD
2	Carbamazepine	17113938	CTD
3	Cocaine	View details 1985292 10543632 17299505 17554526 20064697	CTD
4	Folic Acid	23690582	CTD
5	Homocysteine	23690582	CTD
6	Methamphetamine	15229250 29802913	CTD
7	Pilocarpine	17113938	CTD
8	Tacrolimus	19779798	CTD
9	Vitamin B 12	23690582	CTD
10	Vitamin B 6	23690582	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Akinetic Mutism	46.7%
2	Anoxic Encephalopathy	46.7%
3	Basal Ganglia Diseases	46.7%
4	Cerebellar Diseases	46.7%
5	Encephalitis	46.7%
6	Encephalomalacia	46.7%
7	Epilepsy	46.7%
8	Hydrocephalus	46.7%
9	Congenital Hydrocephalus	46.7%
10	Hypothalamic Diseases	46.7%
11	Thalamic Diseases	46.7%
12	Intracranial Hypertension	46.7%
13	Aura	46.7%
14	Leukoencephalopathy	46.7%
15	Neuroaxonal Dystrophies	46.7%
16	Headache Disorders	46.7%
17	Intracranial Hypotension	46.7%
18	Brain Edema	46.7%
19	Brain Hypoxia	46.7%
20	Aqueductal Stenosis	46.7%
21	Posterior Leukoencephalopathy Syndrome	41.6%
22	Posterior reversible encephalopathy syndrome	41.6%
23	Subdural Effusion	40.7%
24	Myoclonic Epilepsy	37.6%
25	Epilepsy, Temporal Lobe	37.6%
26	Epilepsy, Rolandic	37.6%
27	Benign Rolandic Epilepsy	37.6%
28	Parkinsonian Disorders	36.3%
29	Meningoencephalitis	35.5%
30	Epilepsies, Partial	34.4%
31	Epilepsy, Generalized	34.4%
32	Pseudotumor Cerebri	34.4%
33	Hypertensive Encephalopathy	34.4%
34	Simple Partial Seizures	34.4%
35	Epilepsy, Reflex	34.4%
36	Basal Ganglia Cerebrovascular Disease	34.4%
37	Headache Disorders, Primary	34.4%
38	Headache Disorders, Secondary	34.4%
39	Medication overuse headache	34.4%
40	Encephalomyelitis	34.1%
41	Juvenile Myoclonic Epilepsy	33.7%
42	Myoclonic Epilepsies, Progressive	33.7%
43	Meige Syndrome	32.6%
44	Cerebral Ventriculitis	32.6%
45	Dandy-Walker Syndrome	32%
46	Brain Diseases, Metabolic	31.8%
47	Cerebrovascular Disorders	31.8%
48	Cerebrovascular Insufficiency	31.8%
49	Dementia	31.8%
50	Dementia, Vascular	31.8%
51	Vascular Headaches	31.4%
52	Hypoxia-Ischemia, Brain	31.2%
53	Meningitis	31%
54	Movement Disorders	31%
55	Pachymeningitis	31%
56	Spinal Cord Diseases	31%
57	Marchiafava-Bignami Disease	30.3%
58	Lewy Body Disease	29.5%
59	Epilepsy, Post-Traumatic	29.2%
60	Multiple System Atrophy	28.9%
61	Post-Traumatic Headache	28.5%
62	Tension Headache	28.5%
63	Epilepsy, Complex Partial	28.5%
64	Migraine Disorders	28.5%
65	Abdominal Migraine	28.5%
66	Status Migrainosus	28.5%
67	Cervicogenic Headache	28.5%
68	Pneumocephalus	27.8%
69	Leukomalacia, Periventricular	27.6%
70	Parkinson Disease	27%
71	Brain Abscess	26.8%
72	Myelitis	26.7%
73	Brain Injuries	26.7%
74	Brain Neoplasms	26.4%
75	Cerebellar Neoplasms	26.3%
76	Cluster Headache	25.5%
77	Migraine with Aura	25.5%
78	Familial Hemiplegic Migraine	25.5%
79	Chronic Paroxysmal Hemicrania	25.5%
80	SUNCT Syndrome	25.5%
81	Paroxysmal Hemicrania	25.5%
82	Brain Death	24.8%
83	Pituitary Diseases	24.7%
84	Creutzfeldt-Jakob disease	24.6%
85	Basal Ganglia Hemorrhage	23.2%
86	Carotid Artery Diseases	23.1%
87	Brain Ischemia	23.1%
88	Cerebrovascular accident	23.1%
89	Kluver-Bucy Syndrome	23.1%
90	Vasospasm, Intracranial	23.1%
91	Intracranial Arterial Diseases	23.1%
92	Pituitary Apoplexy	23%
93	Neuroleptic Malignant Syndrome	22.7%
94	Myelinolysis, Central Pontine	22.7%
95	Brain Infarction	22.6%
96	Dystonia Musculorum Deformans	22.4%
97	Huntington Disease	22%
98	Central Nervous System Infection	22%
99	Lafora Disease	22%
100	Unverricht-Lundborg Syndrome	22%
101	Striatonigral Degeneration	21.8%
102	Ocular Motility Disorders	21.8%
103	Cyclophoria	21.8%
104	Epidural Abscess	21.7%
105	Putaminal Hemorrhage	21%
106	Presenile dementia	20.7%
107	Senile dementia	20.7%
108	Infarction, Middle Cerebral Artery	20.6%
109	Infarction, Anterior Cerebral Artery	20.6%
110	Infarction, Posterior Cerebral Artery	20.6%
111	Amblyopia	20.6%
112	Prion Diseases	20.5%
113	Cerebral Infarction	20.1%
114	Brain Stem Infarctions	20.1%
115	Arachnoiditis	20%
116	Aseptic Meningitis	20%
117	Syringomyelia	20%
118	Essential Tremor	20%
119	Familial Tremor	20%
120	Pneumorrhachis	20%
121	Writer's Cramp	20%
122	Empty Sella Syndrome	19.6%
123	Hyperpituitarism	19.6%
124	Hypopituitarism	19.6%
125	Hypophysitis	19.6%
126	Brain Injuries, Diffuse	19.5%
127	Traumatic Brain Injury	19.5%
128	Cerebellar Ataxia	19.4%
129	Supratentorial Neoplasms	19.4%
130	MPTP Poisoning	19.3%
131	Pituitary Adenoma	19.3%
132	Pituitary Neoplasms	19.3%
133	Leukoencephalopathy, Progressive Multifocal	19.3%
134	Cerebral Arterial Diseases	18.9%
135	Vertebrobasilar Insufficiency	18.9%
136	Lateral Medullary Syndrome	18.9%
137	Basilar Artery Stenosis	18.9%
138	Vertebral Artery Stenosis	18.9%
139	Intracranial Hemorrhage, Hypertensive	18.9%
140	Transient Cerebral Ischemia	18.9%
141	Limbic Encephalitis	18.6%
142	Cranial nerve diseases	18.5%
143	Demyelinating Diseases	18.5%
144	Demyelination	18.5%
145	Neuromuscular Diseases	18.5%
146	Chronobiology Disorders	18.5%
147	Shy-Drager Syndrome	18.3%
148	Carotid Artery Injuries	18.1%
149	Moyamoya Disease	17.9%
150	Progressive supranuclear palsy	17.6%
151	Lupus Vasculitis, Central Nervous System	17.5%
152	Reye Syndrome	17.4%
153	Meningitis, Bacterial	17.4%
154	Meningitis, Fungal	17.4%
155	Brain Hemorrhage, Traumatic	17.2%
156	Intracranial Embolism and Thrombosis	17.2%
157	Hepatic Encephalopathy	17.2%
158	Hyperprolactinemia	17.2%
159	Leukoencephalitis, Acute Hemorrhagic	17%
160	Subclavian Steal Syndrome	16.9%
161	Pick Disease of the Brain	16.9%
162	Encephalomyelitis, Acute Disseminated	16.7%
163	Spinal Muscular Atrophy	16.7%
164	Progressive Muscular Atrophy	16.7%
165	Amnesia, Transient Global	16.6%
166	Paraneoplastic Cerebellar Degeneration	16.4%
167	Stiff-Person Syndrome	16.4%
168	Spinal Cord Injuries	16.1%
169	Diffuse Axonal Injury	16.1%
170	Brain Stem Neoplasms	16%
171	Friedreich Ataxia	16%
172	Poliomyelitis	15.9%
173	Asterixis	15.3%
174	Ballismus	15.3%
175	Toxoplasmosis, Cerebral	15.2%
176	Vasculitis, Central Nervous System	15.1%
177	Hepatolenticular Degeneration	14.9%
178	Canavan Disease	14.9%
179	Alexander Disease	14.9%
180	Choroid Plexus Papilloma	14.4%
181	Carotid Stenosis	14.3%
182	Intracranial Aneurysm	14.3%
183	Intracranial Arteriosclerosis	14.2%
184	Cerebral Atherosclerosis	14.2%
185	Subarachnoid Hemorrhage	14.2%
186	Cerebral Arteriosclerosis	14.2%
187	Cerebral Hemorrhage	14.2%
188	Cerebral Thrombosis	14.1%
189	Intracranial Embolism	14.1%
190	Intracranial Thrombosis	14.1%
191	Ophthalmoplegic Migraine	14%
192	Motor Neuron Disease	14%
193	Brain Diseases, Metabolic, Inborn	13.9%
194	Subarachnoid Hemorrhage, Traumatic	13.8%
195	Carotid Artery, Internal, Dissection	13.8%
196	Central Nervous System Fungal Infections	13.6%
197	Conus Medullaris Syndrome	13.6%
198	Spinal Cord Vascular Diseases	13.6%
199	Subacute Combined Degeneration	13.5%
200	Amyotrophic Lateral Sclerosis	13.3%
201	Frontotemporal dementia	13.2%
202	Spinal Cord Neoplasms	13.2%
203	Miller Fisher Syndrome	13.2%
204	Mitochondrial Encephalomyopathies	13.1%
205	Brain Contusion	12.9%
206	Acromegaly	12.9%
207	Chronic Fatigue Syndrome	12.9%
208	Tuberculosis, Meningeal	12.8%
209	Trauma, Nervous System	12.8%
210	Subacute Sclerosing Panencephalitis	12.7%
211	Cerebral Amyloid Angiopathy	12.7%
212	Sinus Thrombosis, Intracranial	12.6%
213	Nervous System Neoplasms	12.2%
214	Neurologic Manifestations	12.2%
215	Neurotoxicity Syndromes	12.2%
216	MELAS Syndrome	12.1%
217	Cavernous Sinus Thrombosis	11.9%
218	Sagittal Sinus Thrombosis	11.9%
219	Vertebral Artery Dissection	11.7%
220	Wernicke Encephalopathy	11.5%
221	AIDS Dementia Complex	11.4%
222	Autonomic Dysreflexia	11.4%
223	Complex Regional Pain Syndromes	11.4%
224	Carotid Artery Thrombosis	11.3%
225	Auditory Perceptual Disorders	11.2%
226	Myelitis, Transverse	10.9%
227	Scrapie	10.9%
228	Central Cord Syndrome	10.9%
229	Adrenoleukodystrophy	10.8%
230	Meningitis, Cryptococcal	10.7%
231	Meningitis, Listeria	10.7%
232	Chorea	10.7%
233	Meningitis, Haemophilus	10.6%
234	Meningitis, Pneumococcal	10.6%
235	Brain Concussion	10.6%
236	Dysautonomia	10.3%
237	Vagus Nerve Disorder	10.3%
238	Glossopharyngeal Neuralgia	10.3%
239	Abducens Nerve Diseases	10.3%
240	Heavy Metal Poisoning, Nervous System	10.3%
241	Neuromuscular Junction Diseases	10.3%
242	Central Nervous System Bacterial Infections	10.3%
243	Tauopathies	10.3%
244	Trochlear Nerve Diseases	10.3%
245	Peripheral Nervous System Diseases	10.3%
246	West Nile Fever	10.2%
247	Polyradiculoneuropathy	10.2%
248	Polyradiculoneuritis	10.2%
249	Akathisia, Drug-Induced	10.1%
250	Ataxia Telangiectasia	10.1%
251	Kernicterus	10%
252	Alice in Wonderland Syndrome	10%
253	Spinal Cord Ischemia	9.9%
254	Torticollis	9.7%
255	Tuberculosis, Central Nervous System	9.7%
256	Restless Legs Syndrome	9.7%
257	Opsoclonus-Myoclonus Syndrome	9.6%
258	Nelson Syndrome	9.6%
259	Sleep Wake Disorders	9.3%
260	Dyskinesia, Drug-Induced	9.1%
261	Progressive bulbar palsy	8.9%
262	Bulbar palsy	8.9%
263	Giant Cell Arteritis	8.8%
264	Temporal Arteritis	8.8%
265	Hematoma, Subdural	8.6%
266	Hematoma, Epidural, Cranial	8.6%
267	Peripheral Nerve Injuries	8.6%
268	Prolactinoma	8.6%
269	Growth Hormone-Secreting Pituitary Adenoma	8.6%
270	Myasthenia Gravis	8.5%
271	Tardive Dyskinesia	8.5%
272	Causalgia	8.2%
273	Anterior Spinal Artery Syndrome	8.1%
274	Galactosemias	8.1%
275	Urea Cycle Disorders, Inborn	8.1%
276	Tyrosinemias	8.1%
277	Guillain-Barre Syndrome	7.9%
278	Fabry Disease	7.9%
279	Hematoma, Subdural, Intracranial	7.9%
280	Hematoma, Subdural, Chronic	7.9%
281	Hematoma, Subdural, Acute	7.9%
282	Reflex Sympathetic Dystrophy	7.7%
283	Nocturnal Myoclonus Syndrome	7.7%
284	Neuroaspergillosis	7.4%
285	Myopathy	7.3%
286	Optic Neuropathy	7.3%
287	Refsum Disease	7.3%
288	Olfactory Nerve Injuries	7.2%
289	Homocystinuria	7.1%
290	Leigh Disease	7.1%
291	Sleep Disorders, Circadian Rhythm	7%
292	Facial Nerve Diseases	7%
293	Craniocerebral Trauma	7%
294	Parasomnia	7%
295	Dyssomnias	7%
296	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	6.9%
297	Vestibulocochlear Nerve Diseases	6.8%
298	Decerebrate State	6.8%
299	Hemiparesis	6.8%
300	Hydranencephaly	6.8%
301	Meningism	6.8%
302	Neural Tube Defects	6.8%
303	Paresis	6.8%
304	Seizures	6.8%
305	Sensation Disorders	6.8%
306	Tethered Cord Syndrome	6.8%
307	Central Nervous System Neoplasms	6.8%
308	Complex partial seizures	6.8%
309	Iniencephaly	6.8%
310	Craniorachischisis	6.8%
311	Exencephaly	6.8%
312	Monoparesis	6.8%
313	Septo-Optic Dysplasia	6.8%
314	Cortical Dysplasia	6.8%
315	Neurogenic Inflammation	6.8%
316	Gait Disorders, Neurologic	6.8%
317	Neuromuscular Manifestations	6.8%
318	Malformations of Cortical Development	6.8%
319	Sweating, Gustatory	6.7%
320	Auriculotemporal Syndrome	6.7%
321	Botulism	6.7%
322	Central Nervous System Cysts	6.7%
323	Lambert-Eaton Myasthenic Syndrome	6.7%
324	Neuritis	6.7%
325	Polyneuritis	6.7%
326	Radiculitis	6.7%
327	Polyneuropathy	6.7%
328	Mononeuritis	6.7%
329	Mononeuropathies	6.7%
330	Brachial Plexus Neuropathies	6.7%
331	Radiculopathy	6.7%
332	Mononeuropathy Multiplex	6.7%
333	Nerve Root Compression	6.7%
334	Multiple Sclerosis	6.6%
335	Brachial Plexus Neuritis	6.5%
336	Neuralgic Amyotrophy	6.5%
337	Carbamoyl-Phosphate Synthase I Deficiency Disease	6.3%
338	Pseudorabies	6.3%
339	Toxoplasmosis, Congenital	6.2%
340	Malaria, Cerebral	6.2%
341	Neuromyelitis Optica	6.2%
342	Neurocysticercosis	6.1%
343	Facial Nerve Injuries	6%
344	Horner Syndrome	6%
345	Tarsal Tunnel Syndrome	5.9%
346	Cauda Equina Syndrome	5.9%
347	Menkes Kinky Hair Syndrome	5.9%
348	Neurosyphilis	5.8%
349	Acrodynia	5.7%
350	Glycogen storage disease type II	5.6%
351	Ophthalmoplegia	5.4%
352	External Ophthalmoplegia	5.4%
353	Pupil Disorders	5.4%
354	Neurobehavioral Manifestations	5.4%
355	Zellweger Syndrome	5.2%
356	Paraneoplastic Encephalomyelitis	5.2%
357	Charcot-Marie-Tooth Disease	5.1%
358	Myasthenia Gravis, Autoimmune, Experimental	5.1%
359	Coma, Post-Head Injury	5.1%
360	Uveomeningoencephalitic Syndrome	5.1%
361	Sturge-Weber Syndrome	5%
362	Vertigo	5%
363	Alcohol-Induced Disorders, Nervous System	5%
364	Jet Lag Syndrome	5%
365	Sciatic Neuropathy	4.9%
366	Ulnar Neuropathies	4.9%
367	Lesion of Sciatic Nerve	4.9%
368	Ulnar Neuritis	4.9%
369	Radial nerve compression	4.9%
370	Radial Tunnel Syndrome	4.9%
371	Peroneal Neuropathies	4.9%
372	Radial Neuropathy	4.9%
373	Median Neuropathy	4.9%
374	Sciatic Nerve Palsy	4.9%
375	Femoral Neuropathy	4.9%
376	Tibial Neuropathy	4.9%
377	Ulnar Nerve Palsy	4.9%
378	Postural Orthostatic Tachycardia Syndrome	4.9%
379	Radial nerve palsy	4.9%
380	Multiple Sclerosis, Chronic Progressive	4.9%
381	Multiple Sclerosis, Relapsing-Remitting	4.9%
382	Lyme Neuroborreliosis	4.9%
383	Gaucher Disease	4.7%
384	Myotonia Congenita	4.6%
385	Waterhouse-Friderichsen Syndrome	4.6%
386	Cerebrospinal Fluid Otorrhea	4.6%
387	Cerebrospinal Fluid Rhinorrhea	4.6%
388	Neuritis, Autoimmune, Experimental	4.6%
389	Gait Ataxia	4.6%
390	Myositis	4.5%
391	Optic Atrophy	4.5%
392	Optic Neuritis	4.5%
393	Papilledema	4.5%
394	Strabismus	4.5%
395	Tolosa-Hunt Syndrome	4.5%
396	Isaacs syndrome	4.5%
397	Arsenic Poisoning	4.5%
398	Myotonic Disorders	4.5%
399	Myasthenic Syndromes, Congenital	4.5%
400	Vocal Cord Paralysis	4.5%
401	Carpal Tunnel Syndrome	4.5%
402	Tay-Sachs Disease	4.5%
403	neurofibroma	4.5%
404	Diabetic Neuropathies	4.4%
405	Facial Injuries	4.4%
406	Facial Neuralgia	4.4%
407	Diabetic Amyotrophy	4.4%
408	Diabetic Autonomic Neuropathy	4.4%
409	Sleep Talking	4.4%
410	Manganese Poisoning	4.4%
411	Sleep Disorders, Intrinsic	4.4%
412	Orthostatic intolerance	4.4%
413	Sciatica	4.4%
414	Tuberous Sclerosis	4.4%
415	Anosmia	4.4%
416	Ataxia	4.4%
417	Athetosis	4.4%
418	Catalepsy	4.4%
419	Dystonia	4.4%
420	Hemiplegia	4.4%
421	Locked-In Syndrome	4.4%
422	Meningeal Neoplasms	4.4%
423	Meningomyelocele	4.4%
424	Muscle Hypertonia	4.4%
425	Muscle hypotonia	4.4%
426	Myoclonus	4.4%
427	Myotonia	4.4%
428	Neuralgia	4.4%
429	Paraplegia	4.4%
430	Pseudobulbar Palsy	4.4%
431	Quadriplegia	4.4%
432	Spasm	4.4%
433	Spastic Paraplegia	4.4%
434	Status Epilepticus	4.4%
435	Taste Disorders	4.4%
436	Tremor	4.4%
437	Spina Bifida	4.4%
438	Monoplegia	4.4%
439	Hypokinesia	4.4%
440	Paraparesis	4.4%
441	Bradykinesia	4.4%
442	Waxy flexibility	4.4%
443	Action Tremor	4.4%
444	Resting Tremor	4.4%
445	Dysosmia	4.4%
446	Quadriparesis	4.4%
447	Mercury Poisoning, Nervous System	4.4%
448	Olfaction Disorders	4.4%
449	Myokymia	4.4%
450	Lead Poisoning, Nervous System	4.4%
451	Vestibular Neuronitis	4.4%
452	Somatosensory Disorders	4.4%
453	Neuropathic pain	4.4%
454	Hyperkinesia	4.4%
455	Intention tremor	4.4%
456	Voice Disorders	4.2%
457	Voice Disturbance	4.2%
458	Niemann-Pick Disease, Type C	4.1%
459	Polyradiculopathy	4.1%
460	Smith-Magenis syndrome	4.1%
461	Cubital Tunnel Syndrome	4%
462	Dural Arteriovenous Fistula	4%
463	Myotonic Dystrophy	3.9%
464	Akathisia	3.8%
465	Restlessness	3.8%
466	Psychomotor Agitation	3.8%
467	Alcohol Withdrawal Seizures	3.7%
468	Hand-Arm Vibration Syndrome	3.6%
469	Gait Apraxia	3.5%
470	Vision Disorders	3.5%
471	Metamorphopsia	3.5%
472	Visual Impairment	3.5%
473	Fibromyalgia	3.4%
474	Optic Neuropathy, Ischemic	3.4%
475	Anterior Ischemic Optic Neuropathy	3.4%
476	Medial Tibial Stress Syndrome	3.4%
477	Facial Hemiatrophy	3.4%
478	Melkersson-Rosenthal Syndrome	3.4%
479	Mitochondrial Myopathies	3.4%
480	Thoracic Outlet Syndrome	3.4%
481	Anisocoria	3.4%
482	Confusion	3.4%
483	Facial paralysis	3.4%
484	Lethargy	3.4%
485	Memory Disorders	3.4%
486	Muscle Cramp	3.4%
487	Perceptual Disorders	3.4%
488	Psychomotor Disorders	3.4%
489	Tonic Pupil	3.4%
490	Eosinophilia-Myalgia Syndrome	3.4%
491	Anhedonia	3.4%
492	Disorientation	3.4%
493	Facial Paresis	3.4%
494	Memory Loss	3.4%
495	Hemisensory Neglect	3.4%
496	Dysacusis	3.4%
497	Optic Nerve Glioma	3.4%
498	Sleep Bruxism	3.3%
499	Reflex, Abnormal	3.3%
500	Hyporeflexia	3.3%
501	Hyperreflexia	3.3%
502	Anencephaly	3.3%
503	Meningocele	3.3%
504	Muscular Atrophy	3.3%
505	Respiratory Paralysis	3.3%
506	Encephalocele	3.3%
507	Esotropia	3.3%
508	Exotropia	3.3%
509	Hypotension, Orthostatic	3.3%
510	Sleep Apnea Syndromes	3.3%
511	Polymyositis	3.3%
512	Post-Exercise Hypotension	3.3%
513	Tetany	3.3%
514	Disorders of Excessive Somnolence	3.3%
515	Sleep Initiation and Maintenance Disorders	3.3%
516	Night Terrors	3.3%
517	Somnambulism	3.3%
518	Trigeminal Nerve Disorder	3.3%
519	Transient Insomnia	3.3%
520	Sleep Paralysis	3.3%
521	Chronic Insomnia	3.3%
522	REM Sleep Behavior Disorder	3.3%
523	Hypersomnia	3.3%
524	Dermal Sinus	3.2%
525	Dysgeusia	3.2%
526	Formication	3.2%
527	Hyperalgesia	3.2%
528	Hyperesthesia	3.2%
529	Hypesthesia	3.2%
530	Language Disorders	3.2%
531	Numbness	3.2%
532	Paresthesia	3.2%
533	Paraparesis, Spastic	3.2%
534	Spina Bifida Cystica	3.2%
535	Trismus	3.2%
536	Spina Bifida Occulta	3.2%
537	Epilepsia Partialis Continua	3.2%
538	Hypogeusia	3.2%
539	Meningeal Carcinomatosis	3.2%
540	Brown-Sequard Syndrome	3.2%
541	Lissencephaly	3.2%
542	Polymicrogyria	3.2%
543	Pachygyria	3.2%
544	Schizencephaly	3.2%
545	Lockjaw	3.2%
546	Allodynia	3.2%
547	Lead Poisoning, Nervous System, Childhood	3.2%
548	Lead Poisoning, Nervous System, Adult	3.2%
549	Periventricular Nodular Heterotopia	3.2%
550	Ageusia	3.2%
551	Alstrom Syndrome	3.1%
552	Classical Lissencephalies and Subcortical Band Heterotopias	2.9%
553	Amyloid Neuropathies, Familial	2.8%
554	Duane Retraction Syndrome	2.7%
555	Consciousness Disorders	2.7%
556	Mental Retardation	2.7%
557	Muscle Weakness	2.7%
558	Depressed Level of Consciousness	2.7%
559	Mental deficiency	2.7%
560	Intellectual Disability	2.7%
561	Mobius Syndrome	2.7%
562	Bell Palsy	2.7%
563	Sleep Apnea, Obstructive	2.7%
564	Sleep Apnea, Central	2.7%
565	Narcolepsy	2.7%
566	Trigeminal Neuralgia	2.7%
567	Kleine-Levin Syndrome	2.7%
568	Catatonia	2.7%
569	Agraphia	2.7%
570	Alexia	2.7%
571	Anomia	2.7%
572	Cluttering	2.7%
573	Language Development Disorders	2.7%
574	Speech Disorders	2.7%
575	Syncope	2.7%
576	Stupor	2.7%
577	Dysgraphia	2.7%
578	Dyslexia	2.7%
579	Presyncope	2.7%
580	Dyslalia	2.7%
581	Herpes Zoster Oticus	2.7%
582	Familial Periodic Paralysis	2.7%
583	Aphonia	2.6%
584	Sleep Deprivation	2.6%
585	Dysphonia	2.6%
586	Acoustic Neuroma	2.6%
587	Eye Injuries	2.6%
588	Neurofibrosarcoma	2.5%
589	Muscular Dystrophy	2.5%
590	Congenital nystagmus	2.5%
591	Orbital Myositis	2.5%
592	Diplopia	2.5%
593	Muscle Rigidity	2.5%
594	Muscle Spasticity	2.5%
595	Scotoma	2.5%
596	Photophobia	2.5%
597	Cogwheel Rigidity	2.5%
598	Hemifacial Spasm	2.5%
599	Amaurosis	2.5%
600	Blindness	2.5%
601	Nuchal Rigidity	2.5%
602	Pyomyositis	2.5%
603	Agnosia	2.4%
604	Apraxias	2.4%
605	Hallucinations	2.4%
606	Hemianopsia	2.4%
607	Hyperacusis	2.4%
608	Tinnitus	2.4%
609	Visual Agnosia	2.4%
610	Anosognosia	2.4%
611	Wernicke-Korsakoff Syndrome	2.4%
612	Phonophobia	2.4%
613	Hearing Loss	2.4%
614	Sarcopenia	2.4%
615	Cataplexy	2.4%
616	Aphasia	2.4%
617	Articulation Disorders	2.4%
618	Echolalia	2.4%
619	Stuttering	2.4%
620	Dysphasia	2.4%
621	Dysarthria	2.3%
622	Optic Atrophy, Hereditary, Leber	2.2%
623	Myalgia	2.2%
624	Kearns-Sayre syndrome	2.2%
625	Neuronal Ceroid-Lipofuscinoses	2.2%
626	Eye Burns	2.1%
627	Welander Distal Myopathy	2%
628	Amaurosis Fugax	2%
629	Blindness, Cortical	2%
630	Dyscalculia	2%
631	Rett Syndrome	2%
632	Deafness	2%
633	Hearing Loss, Sudden	2%
634	Gerstmann Syndrome	2%
635	Hearing Loss, Bilateral	2%
636	Hearing Loss, High-Frequency	2%
637	Hearing Loss, Mixed Conductive-Sensorineural	2%
638	Prosopagnosia	2%
639	Apraxia, Ideomotor	2%
640	Persistent Vegetative State	2%
641	Charles Bonnet Syndrome	2%
642	Hearing Loss, Unilateral	2%
643	Complete Hearing Loss	2%
644	Alien Hand Syndrome	2%
645	Deaf Mutism	2%
646	Amnesia	2%
647	Delirium	2%
648	Dissociative Amnesia	2%
649	Color blindness	2%
650	Global Amnesia	2%
651	Cri-du-Chat Syndrome	2%
652	Down Syndrome	2%
653	Trisomy 21	2%
654	POEMS Syndrome	2%
655	Meningioma	2%
656	Williams Syndrome	2%
657	Microcephaly	2%
658	Macrocephaly	2%
659	Hypokalemic periodic paralysis	1.9%
660	Porencephaly	1.9%
661	Aicardi's syndrome	1.9%
662	Hoarseness	1.9%
663	Cockayne Syndrome	1.9%
664	Alcohol Withdrawal Delirium	1.9%
665	Mutism	1.8%
666	Selective Mutism	1.8%
667	Alexia, Pure	1.7%
668	Dermatomyositis	1.7%
669	Corneal Scar	1.7%
670	Holoprosencephaly	1.7%
671	Prader-Willi Syndrome	1.6%
672	Muscular Dystrophy, Duchenne	1.6%
673	Phantom pain	1.6%
674	Phantom Limb Pain	1.6%
675	Retrograde amnesia	1.6%
676	Amnesia, Anterograde	1.6%
677	Corneal Perforation	1.5%
678	Fragile X Syndrome	1.3%
679	Rubinstein-Taybi Syndrome	1.2%
680	Mucopolysaccharidosis II	0.9%

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