MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Leukoencephalopathy, Progressive Multifocal

(UMLS:C0023524)

Definition:: An opportunistic viral infection of the central nervous system associated with conditions that impair cell-mediated immunity (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME and other IMMUNOLOGIC DEFICIENCY SYNDROMES; HEMATOLOGIC NEOPLASMS; IMMUNOSUPPRESSION; and COLLAGEN DISEASES). The causative organism is JC Polyomavirus (JC VIRUS) which primarily affects oligodendrocytes, resulting in multiple areas of demyelination. Clinical manifestations include DEMENTIA; ATAXIA; visual disturbances; and other focal neurologic deficits, generally progressing to a vegetative state within 6 months. (From Joynt, Clinical Neurology, 1996, Ch26, pp36-7)
UMLS ID:: C0023524
MeSH ID:: D007968

Classification 1:

Name:

Virus Diseases
MeSH Tree Number(s):: C02.182.525.500|C02.256.721.500|C02.290.575|C02.839.550

Classification 2:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.140.430.520.750.500|C10.228.140.695.750|C10.228.228.245.340.500|C10.228.228.399.750.500|C10.314.450

Synonym(s)

Leukoencephalopathy, Progressive Multifocal

Multifocal leukoencephalopathy

Multifocal leukoencephalopathy, NOS

PML

PML - Progressive multifocal leukoencephalopathy

PMLE - Progressive multifocal leucoencephalopathy

PMLE - Progressive multifocal leukoencephalopathy

PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY

Progressive Multifocal Leukoencephalopathy

10.

Progressive multifocal leucoencephalopathy

11.

Progressive multifocal leukoencephalopathy

12.

leukoencephalopathy; multifocal

13.

multifocal leukoencephalopathy

14.

multifocal; leukoencephalopathy

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Camptothecin	9149702	CTD
2	Cidofovir	10460453 17297588	CTD
3	Cocaine	7955717 21353145	CTD
4	Cyclophosphamide	9149702	CTD
5	Cyclosporine	7947043	CTD
6	Fluorouracil	8354144	CTD
7	Mycophenolic Acid	20657885	CTD
8	Ranitidine	8354144	CTD
9	Ubiquinone	21353145	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Subacute Sclerosing Panencephalitis	60.7%
2	Meningoencephalitis	48%
3	West Nile Fever	45.9%
4	Encephalomyelitis	36.5%
5	Epidural Abscess	33%
6	Leukoencephalopathy, Progressive Multifocal	31%
7	Pseudorabies	30.2%
8	Dementia, Vascular	30.2%
9	Multiple System Atrophy	29.8%
10	Brain Abscess	29.5%
11	Cerebral Ventriculitis	28.5%
12	Myelitis	28.4%
13	Pneumocephalus	28.3%
14	Subdural Effusion	28.3%
15	Leukoencephalitis, Acute Hemorrhagic	28.3%
16	Chronic Fatigue Syndrome	28.2%
17	Lupus Vasculitis, Central Nervous System	27.5%
18	Lewy Body Disease	26.8%
19	Limbic Encephalitis	26.2%
20	Poliomyelitis	26%
21	Dandy-Walker Syndrome	25.6%
22	Ocular Motility Disorders	25.4%
23	Cyclophoria	25.4%
24	Prion Diseases	25.3%
25	Subacute Combined Degeneration	25.2%
26	Marchiafava-Bignami Disease	24%
27	Posterior Leukoencephalopathy Syndrome	23.8%
28	Posterior reversible encephalopathy syndrome	23.8%
29	Myelitis, Transverse	23.4%
30	Ophthalmoplegic Migraine	23.3%
31	Progressive supranuclear palsy	23.2%
32	Stiff-Person Syndrome	23.1%
33	Parkinsonian Disorders	22.2%
34	Huntington Disease	22.1%
35	Myelinolysis, Central Pontine	22%
36	Warts	21.7%
37	Epilepsy, Post-Traumatic	21.5%
38	Rift Valley Fever	21.5%
39	Parkinson Disease	21.2%
40	Encephalomyelitis, Acute Disseminated	21.1%
41	Meningitis	21.1%
42	Movement Disorders	21.1%
43	Pachymeningitis	21.1%
44	Spinal Cord Diseases	21.1%
45	Polyradiculoneuropathy	20.6%
46	Polyradiculoneuritis	20.6%
47	Brain Injuries	20.6%
48	Brain Neoplasms	20.5%
49	Amyotrophic Lateral Sclerosis	20.3%
50	Basal Ganglia Cerebrovascular Disease	20.3%
51	Miller Fisher Syndrome	20.2%
52	Toxoplasmosis, Cerebral	20.1%
53	Meningitis, Bacterial	20.1%
54	Meningitis, Fungal	20.1%
55	Canavan Disease	20%
56	Alexander Disease	20%
57	Creutzfeldt-Jakob disease	20%
58	Striatonigral Degeneration	19.7%
59	Dystonia Musculorum Deformans	19.6%
60	Condylomata Acuminata	19.4%
61	Akinetic Mutism	19.3%
62	Anoxic Encephalopathy	19.3%
63	Basal Ganglia Diseases	19.3%
64	Brain Damage, Chronic	19.3%
65	Cerebellar Diseases	19.3%
66	Encephalomalacia	19.3%
67	Epilepsy	19.3%
68	Hydrocephalus	19.3%
69	Congenital Hydrocephalus	19.3%
70	Hypothalamic Diseases	19.3%
71	Thalamic Diseases	19.3%
72	Intracranial Hypertension	19.3%
73	Aura	19.3%
74	Neuroaxonal Dystrophies	19.3%
75	Headache Disorders	19.3%
76	Intracranial Hypotension	19.3%
77	Brain Edema	19.3%
78	Brain Hypoxia	19.3%
79	Aqueductal Stenosis	19.3%
80	Spinal Muscular Atrophy	19.2%
81	Progressive Muscular Atrophy	19.2%
82	Hepatolenticular Degeneration	19.2%
83	Acquired Immunodeficiency Syndrome	19%
84	AIDS related complex	19%
85	Leukomalacia, Periventricular	18.8%
86	Shy-Drager Syndrome	18.3%
87	Meige Syndrome	18.2%
88	Cerebellar Neoplasms	18.1%
89	Brain Death	18%
90	Spinal Cord Injuries	17.9%
91	Dengue Fever	17.8%
92	Yellow Fever	17.8%
93	Restless Legs Syndrome	17.7%
94	Amblyopia	17.7%
95	Brain Diseases, Metabolic	17.6%
96	Cerebrovascular Disorders	17.6%
97	Cerebrovascular Insufficiency	17.6%
98	Dementia	17.6%
99	Asterixis	17.6%
100	Ballismus	17.6%
101	Neuroleptic Malignant Syndrome	17.6%
102	Tuberculosis, Meningeal	17.4%
103	Vascular Headaches	17.4%
104	Hypoxia-Ischemia, Brain	17.3%
105	Central Nervous System Fungal Infections	17.3%
106	Neuromyelitis Optica	17.1%
107	Epstein-Barr Virus Infections	17.1%
108	Opsoclonus-Myoclonus Syndrome	16.8%
109	Simian Acquired Immunodeficiency Syndrome	16.7%
110	Hemorrhagic Fever, Crimean	16.7%
111	MPTP Poisoning	16.5%
112	Guillain-Barre Syndrome	16.5%
113	Brain Hemorrhage, Traumatic	16.4%
114	Motor Neuron Disease	16.1%
115	Basal Ganglia Hemorrhage	16%
116	Adrenoleukodystrophy	16%
117	Central Nervous System Bacterial Infections	16%
118	Epidermodysplasia Verruciformis	15.8%
119	Myoclonic Epilepsy	15.8%
120	Epilepsy, Temporal Lobe	15.8%
121	Epilepsy, Rolandic	15.8%
122	Benign Rolandic Epilepsy	15.8%
123	AIDS Dementia Complex	15.8%
124	Pituitary Adenoma	15.8%
125	Pituitary Neoplasms	15.8%
126	Cranial nerve diseases	15.7%
127	Neuromuscular Diseases	15.7%
128	Chronobiology Disorders	15.7%
129	Hepatitis E	15.7%
130	Amnesia, Transient Global	15.7%
131	Hepatitis B	15.6%
132	Molluscum Contagiosum	15.6%
133	Carotid Artery Injuries	15.1%
134	Akathisia, Drug-Induced	15.1%
135	Vasculitis, Central Nervous System	15%
136	Arbovirus Infections	15%
137	Dyskinesia, Drug-Induced	14.8%
138	Presenile dementia	14.7%
139	Senile dementia	14.7%
140	Spinal Cord Neoplasms	14.7%
141	Phlebotomus Fever	14.6%
142	Trauma, Nervous System	14.6%
143	Scrapie	14.5%
144	Friedreich Ataxia	14.4%
145	Erythema Infectiosum	14.4%
146	Nervous System Neoplasms	14.4%
147	Neurologic Manifestations	14.4%
148	Neurotoxicity Syndromes	14.4%
149	Encephalitis	14%
150	Hepatitis, Viral, Human	13.6%
151	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	13.6%
152	Paraneoplastic Cerebellar Degeneration	13.5%
153	Viremia	13.5%
154	Murine Acquired Immunodeficiency Syndrome	13.5%
155	Lafora Disease	13.5%
156	Unverricht-Lundborg Syndrome	13.5%
157	Herpesviridae Infections	13.4%
158	Pituitary Apoplexy	13.4%
159	Zika Virus Infection	13.4%
160	Hepatitis C	13.4%
161	Sleep Wake Disorders	13.3%
162	Brain Infarction	13.3%
163	Brain Injuries, Diffuse	13.2%
164	Traumatic Brain Injury	13.2%
165	Cerebellar Ataxia	13.2%
166	Supratentorial Neoplasms	13.2%
167	Putaminal Hemorrhage	13.1%
168	Lambert-Eaton Myasthenic Syndrome	13.1%
169	Herpes Zoster Ophthalmicus	13.1%
170	Autonomic Dysreflexia	13%
171	Complex Regional Pain Syndromes	13%
172	Keratitis, Herpetic	12.9%
173	Cytomegalovirus Retinitis	12.9%
174	Exanthema Subitum	12.8%
175	Opportunistic Infections	12.7%
176	Juvenile Myoclonic Epilepsy	12.6%
177	Myoclonic Epilepsies, Progressive	12.6%
178	Infarction, Middle Cerebral Artery	12.5%
179	Infarction, Anterior Cerebral Artery	12.5%
180	Infarction, Posterior Cerebral Artery	12.5%
181	Persistent Vegetative State	12.5%
182	Hepatitis, Viral, Animal	12.5%
183	Meningitis, Cryptococcal	12.5%
184	Pneumonia, Viral	12.4%
185	Meningitis, Listeria	12.4%
186	Meningitis, Haemophilus	12.4%
187	Meningitis, Pneumococcal	12.4%
188	Multiple Sclerosis	12.3%
189	Arachnoiditis	12.3%
190	Aseptic Meningitis	12.3%
191	Syringomyelia	12.3%
192	Leukoencephalopathy	12.3%
193	Essential Tremor	12.3%
194	Familial Tremor	12.3%
195	Pneumorrhachis	12.3%
196	Writer's Cramp	12.3%
197	Hepatitis A	12.2%
198	Cerebral Palsy	12.2%
199	Epilepsies, Partial	12.2%
200	Epilepsy, Generalized	12.2%
201	Pseudotumor Cerebri	12.2%
202	Hypertensive Encephalopathy	12.2%
203	Simple Partial Seizures	12.2%
204	Epilepsy, Reflex	12.2%
205	Headache Disorders, Primary	12.2%
206	Headache Disorders, Secondary	12.2%
207	Medication overuse headache	12.2%
208	Hemorrhagic Fever, American	12.1%
209	Lassa Fever	12.1%
210	Peripheral Nerve Injuries	11.9%
211	Myasthenia Gravis	11.9%
212	Brain Diseases	11.8%
213	Demyelinating Diseases	11.7%
214	Demyelination	11.7%
215	Eczema Herpeticum	11.6%
216	Sexually Transmitted Diseases	11.6%
217	Ataxia Telangiectasia	11.5%
218	Bell Palsy	11.4%
219	Mitochondrial Encephalomyopathies	11.4%
220	Pituitary Diseases	11.3%
221	Conus Medullaris Syndrome	11.2%
222	Spinal Cord Vascular Diseases	11.2%
223	Olfactory Nerve Injuries	11.2%
224	Central Cord Syndrome	11.1%
225	Sleep Disorders, Circadian Rhythm	11.1%
226	MELAS Syndrome	11.1%
227	Carotid Artery Diseases	11.1%
228	Central Nervous System Infection	11.1%
229	Brain Ischemia	11.1%
230	Cerebrovascular accident	11.1%
231	Kluver-Bucy Syndrome	11.1%
232	Vasospasm, Intracranial	11.1%
233	Intracranial Arterial Diseases	11.1%
234	Moyamoya Disease	11.1%
235	Chorea	11.1%
236	Botulism	10.9%
237	Central Nervous System Cysts	10.9%
238	Hemorrhagic Fever with Renal Syndrome	10.9%
239	Subarachnoid Hemorrhage, Traumatic	10.9%
240	Carotid Artery, Internal, Dissection	10.9%
241	Genital Herpes	10.8%
242	Tuberculosis, Central Nervous System	10.8%
243	Causalgia	10.7%
244	Herpes Labialis	10.7%
245	Hepatitis B, Chronic	10.7%
246	Cerebral Infarction	10.6%
247	Brain Stem Infarctions	10.6%
248	Auditory Perceptual Disorders	10.6%
249	Facial Nerve Injuries	10.4%
250	Refsum Disease	10.2%
251	Reye Syndrome	10.2%
252	Intracranial Embolism and Thrombosis	10.2%
253	Hepatic Encephalopathy	10.2%
254	Brain Concussion	10.1%
255	AIDS-Related Opportunistic Infections	10.1%
256	Tuberous Sclerosis	10.1%
257	Vertebral Artery Dissection	10%
258	HIV Infections	10%
259	Neuroaspergillosis	9.9%
260	Burkitt Lymphoma	9.9%
261	Progressive bulbar palsy	9.9%
262	Bulbar palsy	9.9%
263	Myasthenia Gravis, Autoimmune, Experimental	9.6%
264	Torticollis	9.6%
265	Horner Syndrome	9.6%
266	Diffuse Axonal Injury	9.6%
267	Brain Stem Neoplasms	9.6%
268	Alice in Wonderland Syndrome	9.5%
269	Frontotemporal dementia	9.5%
270	Brain Diseases, Metabolic, Inborn	9.4%
271	Orthomyxoviridae Infections	9.4%
272	Picornaviridae Infections	9.4%
273	Reoviridae Infections	9.4%
274	Retroviridae Infections	9.4%
275	Cytomegalovirus Infections	9.3%
276	Smallpox	9.3%
277	Varicella Zoster Virus Infection	9.3%
278	Lateral Medullary Syndrome	9.3%
279	Hepatitis C, Chronic	9.2%
280	Neurosyphilis	9.1%
281	Herpes Zoster Oticus	9.1%
282	Multiple Sclerosis, Chronic Progressive	8.9%
283	Multiple Sclerosis, Relapsing-Remitting	8.9%
284	Jet Lag Syndrome	8.9%
285	Brain Contusion	8.9%
286	Dysautonomia	8.8%
287	Vagus Nerve Disorder	8.8%
288	Glossopharyngeal Neuralgia	8.8%
289	Abducens Nerve Diseases	8.8%
290	Heavy Metal Poisoning, Nervous System	8.8%
291	Neuromuscular Junction Diseases	8.8%
292	Tauopathies	8.8%
293	Trochlear Nerve Diseases	8.8%
294	Peripheral Nervous System Diseases	8.8%
295	Giant Cell Arteritis	8.8%
296	Temporal Arteritis	8.8%
297	Post-Traumatic Headache	8.7%
298	Tension Headache	8.7%
299	Epilepsy, Complex Partial	8.7%
300	Migraine Disorders	8.7%
301	Abdominal Migraine	8.7%
302	Status Migrainosus	8.7%
303	Cervicogenic Headache	8.7%
304	Wernicke Encephalopathy	8.7%
305	Charcot-Marie-Tooth Disease	8.5%
306	Herpangina	8.4%
307	Lyme Neuroborreliosis	8.4%
308	Ophthalmoplegia	8.4%
309	External Ophthalmoplegia	8.4%
310	Reflex Sympathetic Dystrophy	8.3%
311	Nocturnal Myoclonus Syndrome	8.3%
312	HIV Seropositivity	8.3%
313	Kernicterus	8.2%
314	Myopathy	8.2%
315	Optic Neuropathy	8.2%
316	Facial Nerve Diseases	8.1%
317	Craniocerebral Trauma	8.1%
318	Parasomnia	8.1%
319	Dyssomnias	8.1%
320	Vestibulocochlear Nerve Diseases	8%
321	Decerebrate State	8%
322	Hemiparesis	8%
323	Hydranencephaly	8%
324	Meningism	8%
325	Neural Tube Defects	8%
326	Paresis	8%
327	Seizures	8%
328	Sensation Disorders	8%
329	Tethered Cord Syndrome	8%
330	Central Nervous System Neoplasms	8%
331	Complex partial seizures	8%
332	Iniencephaly	8%
333	Craniorachischisis	8%
334	Exencephaly	8%
335	Monoparesis	8%
336	Septo-Optic Dysplasia	8%
337	Cortical Dysplasia	8%
338	Neurogenic Inflammation	8%
339	Gait Disorders, Neurologic	8%
340	Neuromuscular Manifestations	8%
341	Malformations of Cortical Development	8%
342	Sweating, Gustatory	8%
343	Auriculotemporal Syndrome	8%
344	Empty Sella Syndrome	8%
345	Hyperpituitarism	8%
346	Hypopituitarism	8%
347	Hypophysitis	8%
348	Cerebral Arterial Diseases	7.9%
349	Vertebrobasilar Insufficiency	7.9%
350	Basilar Artery Stenosis	7.9%
351	Vertebral Artery Stenosis	7.9%
352	Intracranial Hemorrhage, Hypertensive	7.9%
353	Transient Cerebral Ischemia	7.9%
354	Superinfection	7.9%
355	Tardive Dyskinesia	7.8%
356	Choroid Plexus Papilloma	7.8%
357	Vocal Cord Paralysis	7.8%
358	Acrodynia	7.6%
359	Myotonic Dystrophy	7.5%
360	Pupil Disorders	7.5%
361	Neurobehavioral Manifestations	7.5%
362	Polyomavirus Infections	7.4%
363	Paraneoplastic Encephalomyelitis	7.4%
364	Uveomeningoencephalitic Syndrome	7.3%
365	Sturge-Weber Syndrome	7.3%
366	Vertigo	7.3%
367	Alcohol-Induced Disorders, Nervous System	7.3%
368	Chickenpox	7.3%
369	Optic Nerve Glioma	7.3%
370	Carotid Stenosis	7.2%
371	Intracranial Aneurysm	7.2%
372	Intracranial Arteriosclerosis	7.2%
373	Cerebral Atherosclerosis	7.2%
374	Subarachnoid Hemorrhage	7.2%
375	Cerebral Arteriosclerosis	7.2%
376	Cerebral Hemorrhage	7.2%
377	Cerebral Thrombosis	7.2%
378	Intracranial Embolism	7.2%
379	Intracranial Thrombosis	7.2%
380	Spinal Cord Ischemia	7.2%
381	Alcohol Withdrawal Seizures	7.2%
382	HIV Wasting Syndrome	7.1%
383	AIDS-Associated Nephropathy	7.1%
384	Hematoma, Subdural	7.1%
385	Hematoma, Epidural, Cranial	7.1%
386	Myotonia Congenita	7%
387	Toxoplasmosis, Congenital	7%
388	Cerebrospinal Fluid Otorrhea	7%
389	Cerebrospinal Fluid Rhinorrhea	7%
390	Neuritis, Autoimmune, Experimental	7%
391	Gait Ataxia	7%
392	Malaria, Cerebral	7%
393	Cluster Headache	7%
394	Migraine with Aura	7%
395	Familial Hemiplegic Migraine	7%
396	Chronic Paroxysmal Hemicrania	7%
397	SUNCT Syndrome	7%
398	Paroxysmal Hemicrania	7%
399	Neurocysticercosis	7%
400	Fabry Disease	6.9%
401	Voice Disorders	6.8%
402	Voice Disturbance	6.8%
403	Brachial Plexus Neuritis	6.8%
404	Neuralgic Amyotrophy	6.8%
405	Waterhouse-Friderichsen Syndrome	6.8%
406	Smith-Magenis syndrome	6.8%
407	Dural Arteriovenous Fistula	6.8%
408	Enterovirus Infections	6.7%
409	Flavivirus Infections	6.7%
410	Paramyxoviridae Infections	6.7%
411	Cardiovirus Infections	6.7%
412	Rhabdoviridae Infections	6.7%
413	Carotid Artery Thrombosis	6.6%
414	Alstrom Syndrome	6.6%
415	HIV-Associated Lipodystrophy Syndrome	6.6%
416	Coma, Post-Head Injury	6.6%
417	Akathisia	6.5%
418	Restlessness	6.5%
419	Psychomotor Agitation	6.5%
420	Hyperprolactinemia	6.3%
421	Subclavian Steal Syndrome	6.3%
422	Pick Disease of the Brain	6.3%
423	Reflex, Abnormal	6.2%
424	Hyporeflexia	6.2%
425	Hyperreflexia	6.2%
426	Foot-and-Mouth Disease	6.2%
427	Common Cold	6.1%
428	Influenza	6.1%
429	Catarrh	6.1%
430	Menkes Kinky Hair Syndrome	6%
431	Tarsal Tunnel Syndrome	6%
432	Cauda Equina Syndrome	6%
433	Acoustic Neuroma	5.9%
434	Hematoma, Subdural, Intracranial	5.9%
435	Hematoma, Subdural, Chronic	5.9%
436	Hematoma, Subdural, Acute	5.9%
437	Gait Apraxia	5.9%
438	Acromegaly	5.8%
439	Cerebral Amyloid Angiopathy	5.8%
440	Sinus Thrombosis, Intracranial	5.8%
441	Galactosemias	5.8%
442	Urea Cycle Disorders, Inborn	5.8%
443	Tyrosinemias	5.8%
444	Amyloid Neuropathies, Familial	5.7%
445	Infectious Mononucleosis	5.6%
446	Carpal Tunnel Syndrome	5.5%
447	neurofibroma	5.5%
448	Sciatica	5.5%
449	Neuritis	5.4%
450	Polyneuritis	5.4%
451	Radiculitis	5.4%
452	Polyneuropathy	5.4%
453	Mononeuritis	5.4%
454	Mononeuropathies	5.4%
455	Brachial Plexus Neuropathies	5.4%
456	Radiculopathy	5.4%
457	Mononeuropathy Multiplex	5.4%
458	Nerve Root Compression	5.4%
459	Homocystinuria	5.4%
460	Leigh Disease	5.4%
461	Coxsackievirus Infections	5.3%
462	Rubella	5.3%
463	Coronavirus Infections	5.3%
464	Nipah Virus Infection	5.3%
465	Hydrophobia	5.3%
466	Anterior Spinal Artery Syndrome	5.2%
467	Cavernous Sinus Thrombosis	5%
468	Sagittal Sinus Thrombosis	5%
469	Prolactinoma	5%
470	Growth Hormone-Secreting Pituitary Adenoma	5%
471	Myositis	5%
472	Optic Atrophy	5%
473	Optic Neuritis	5%
474	Papilledema	5%
475	Strabismus	5%
476	Tolosa-Hunt Syndrome	5%
477	Isaacs syndrome	5%
478	Arsenic Poisoning	5%
479	Myotonic Disorders	5%
480	Myasthenic Syndromes, Congenital	5%
481	Diabetic Neuropathies	4.9%
482	Facial Injuries	4.9%
483	Facial Neuralgia	4.9%
484	Diabetic Amyotrophy	4.9%
485	Diabetic Autonomic Neuropathy	4.9%
486	Sleep Talking	4.9%
487	Manganese Poisoning	4.9%
488	Sleep Disorders, Intrinsic	4.9%
489	Orthostatic intolerance	4.9%
490	Anosmia	4.9%
491	Ataxia	4.9%
492	Athetosis	4.9%
493	Catalepsy	4.9%
494	Dystonia	4.9%
495	Hemiplegia	4.9%
496	Locked-In Syndrome	4.9%
497	Meningeal Neoplasms	4.9%
498	Meningomyelocele	4.9%
499	Muscle Hypertonia	4.9%
500	Muscle hypotonia	4.9%
501	Myoclonus	4.9%
502	Myotonia	4.9%
503	Neuralgia	4.9%
504	Paraplegia	4.9%
505	Pseudobulbar Palsy	4.9%
506	Quadriplegia	4.9%
507	Spasm	4.9%
508	Spastic Paraplegia	4.9%
509	Status Epilepticus	4.9%
510	Taste Disorders	4.9%
511	Tremor	4.9%
512	Spina Bifida	4.9%
513	Monoplegia	4.9%
514	Hypokinesia	4.9%
515	Paraparesis	4.9%
516	Bradykinesia	4.9%
517	Waxy flexibility	4.9%
518	Action Tremor	4.9%
519	Resting Tremor	4.9%
520	Dysosmia	4.9%
521	Quadriparesis	4.9%
522	Mercury Poisoning, Nervous System	4.9%
523	Olfaction Disorders	4.9%
524	Myokymia	4.9%
525	Lead Poisoning, Nervous System	4.9%
526	Vestibular Neuronitis	4.9%
527	Somatosensory Disorders	4.9%
528	Neuropathic pain	4.9%
529	Hyperkinesia	4.9%
530	Intention tremor	4.9%
531	Porcine Reproductive and Respiratory Syndrome	4.9%
532	HTLV-I Infections	4.8%
533	Cubital Tunnel Syndrome	4.8%
534	Classical Lissencephalies and Subcortical Band Heterotopias	4.7%
535	Nelson Syndrome	4.7%
536	Measles	4.6%
537	Pleurodynia, Epidemic	4.6%
538	Respiratory Syncytial Virus Infections	4.6%
539	Hand-Arm Vibration Syndrome	4.6%
540	Vision Disorders	4.6%
541	Metamorphopsia	4.6%
542	Visual Impairment	4.6%
543	Fibromyalgia	4.6%
544	Optic Neuropathy, Ischemic	4.6%
545	Anterior Ischemic Optic Neuropathy	4.6%
546	Medial Tibial Stress Syndrome	4.6%
547	Zellweger Syndrome	4.6%
548	Facial Hemiatrophy	4.5%
549	Melkersson-Rosenthal Syndrome	4.5%
550	Mitochondrial Myopathies	4.5%
551	Anisocoria	4.5%
552	Confusion	4.5%
553	Facial paralysis	4.5%
554	Lethargy	4.5%
555	Memory Disorders	4.5%
556	Muscle Cramp	4.5%
557	Perceptual Disorders	4.5%
558	Psychomotor Disorders	4.5%
559	Tonic Pupil	4.5%
560	Eosinophilia-Myalgia Syndrome	4.5%
561	Anhedonia	4.5%
562	Disorientation	4.5%
563	Facial Paresis	4.5%
564	Memory Loss	4.5%
565	Hemisensory Neglect	4.5%
566	Dysacusis	4.5%
567	Kearns-Sayre syndrome	4.5%
568	Sleep Bruxism	4.5%
569	Vesicular Stomatitis	4.5%
570	Anencephaly	4.5%
571	Meningocele	4.5%
572	Muscular Atrophy	4.5%
573	Respiratory Paralysis	4.5%
574	Encephalocele	4.5%
575	Tetany	4.5%
576	Carbamoyl-Phosphate Synthase I Deficiency Disease	4.3%
577	Gastroenteritis, Transmissible, of Swine	4.3%
578	Severe Acute Respiratory Syndrome	4.3%
579	Duane Retraction Syndrome	4.2%
580	Mumps	4.2%
581	Consciousness Disorders	4.2%
582	Mental Retardation	4.2%
583	Muscle Weakness	4.2%
584	Depressed Level of Consciousness	4.2%
585	Mental deficiency	4.2%
586	Intellectual Disability	4.2%
587	Mobius Syndrome	4.2%
588	Catatonia	4.2%
589	Familial Periodic Paralysis	4.2%
590	Aphonia	4.2%
591	Sleep Deprivation	4.2%
592	Dysphonia	4.2%
593	Optic Atrophy, Hereditary, Leber	4.1%
594	Alexia	4.1%
595	Dyslexia	4.1%
596	Glycogen storage disease type II	4%
597	Myalgia	3.9%
598	Neuronal Ceroid-Lipofuscinoses	3.8%
599	Neurofibrosarcoma	3.8%
600	Sciatic Neuropathy	3.7%
601	Ulnar Neuropathies	3.7%
602	Lesion of Sciatic Nerve	3.7%
603	Ulnar Neuritis	3.7%
604	Radial nerve compression	3.7%
605	Radial Tunnel Syndrome	3.7%
606	Peroneal Neuropathies	3.7%
607	Radial Neuropathy	3.7%
608	Median Neuropathy	3.7%
609	Sciatic Nerve Palsy	3.7%
610	Femoral Neuropathy	3.7%
611	Tibial Neuropathy	3.7%
612	Ulnar Nerve Palsy	3.7%
613	Postural Orthostatic Tachycardia Syndrome	3.7%
614	Radial nerve palsy	3.7%
615	Aicardi's syndrome	3.6%
616	Hoarseness	3.6%
617	Cockayne Syndrome	3.6%
618	Alcohol Withdrawal Delirium	3.6%
619	Thoracic Outlet Syndrome	3.4%
620	Esotropia	3.4%
621	Exotropia	3.4%
622	Hypotension, Orthostatic	3.4%
623	Sleep Apnea Syndromes	3.4%
624	Polymyositis	3.4%
625	Post-Exercise Hypotension	3.4%
626	Disorders of Excessive Somnolence	3.4%
627	Sleep Initiation and Maintenance Disorders	3.4%
628	Night Terrors	3.4%
629	Somnambulism	3.4%
630	Trigeminal Nerve Disorder	3.4%
631	Transient Insomnia	3.4%
632	Sleep Paralysis	3.4%
633	Chronic Insomnia	3.4%
634	REM Sleep Behavior Disorder	3.4%
635	Hypersomnia	3.4%
636	Dermal Sinus	3.4%
637	Dysgeusia	3.4%
638	Formication	3.4%
639	Hyperalgesia	3.4%
640	Hyperesthesia	3.4%
641	Hypesthesia	3.4%
642	Language Disorders	3.4%
643	Numbness	3.4%
644	Paresthesia	3.4%
645	Paraparesis, Spastic	3.4%
646	Spina Bifida Cystica	3.4%
647	Trismus	3.4%
648	Spina Bifida Occulta	3.4%
649	Epilepsia Partialis Continua	3.4%
650	Hypogeusia	3.4%
651	Meningeal Carcinomatosis	3.4%
652	Brown-Sequard Syndrome	3.4%
653	Lissencephaly	3.4%
654	Polymicrogyria	3.4%
655	Pachygyria	3.4%
656	Schizencephaly	3.4%
657	Lockjaw	3.4%
658	Allodynia	3.4%
659	Lead Poisoning, Nervous System, Childhood	3.4%
660	Lead Poisoning, Nervous System, Adult	3.4%
661	Periventricular Nodular Heterotopia	3.4%
662	Ageusia	3.4%
663	Holoprosencephaly	3.4%
664	Gaucher Disease	3.3%
665	Eye Injuries	3.2%
666	Muscular Dystrophy	3.1%
667	Congenital nystagmus	3.1%
668	Orbital Myositis	3.1%
669	Diplopia	3.1%
670	Muscle Rigidity	3.1%
671	Muscle Spasticity	3.1%
672	Scotoma	3.1%
673	Photophobia	3.1%
674	Cogwheel Rigidity	3.1%
675	Hemifacial Spasm	3.1%
676	Amaurosis	3.1%
677	Blindness	3.1%
678	Nuchal Rigidity	3.1%
679	Pyomyositis	3.1%
680	Agnosia	3.1%
681	Apraxias	3.1%
682	Hallucinations	3.1%
683	Hemianopsia	3.1%
684	Hyperacusis	3.1%
685	Tinnitus	3.1%
686	Visual Agnosia	3.1%
687	Anosognosia	3.1%
688	Wernicke-Korsakoff Syndrome	3.1%
689	Phonophobia	3.1%
690	Hearing Loss	3.1%
691	Sarcopenia	3.1%
692	Tay-Sachs Disease	2.9%
693	Polyradiculopathy	2.9%
694	Niemann-Pick Disease, Type C	2.9%
695	Amnesia	2.9%
696	Delirium	2.9%
697	Dissociative Amnesia	2.9%
698	Color blindness	2.9%
699	Global Amnesia	2.9%
700	Cri-du-Chat Syndrome	2.9%
701	Down Syndrome	2.9%
702	Trisomy 21	2.9%
703	POEMS Syndrome	2.9%
704	Meningioma	2.9%
705	Williams Syndrome	2.9%
706	Microcephaly	2.9%
707	Macrocephaly	2.9%
708	Hypokalemic periodic paralysis	2.9%
709	Porencephaly	2.8%
710	Prader-Willi Syndrome	2.7%
711	Phantom pain	2.6%
712	Phantom Limb Pain	2.6%
713	Sleep Apnea, Obstructive	2.6%
714	Sleep Apnea, Central	2.6%
715	Narcolepsy	2.6%
716	Trigeminal Neuralgia	2.6%
717	Kleine-Levin Syndrome	2.6%
718	Agraphia	2.6%
719	Anomia	2.6%
720	Cluttering	2.6%
721	Language Development Disorders	2.6%
722	Speech Disorders	2.6%
723	Syncope	2.6%
724	Stupor	2.6%
725	Dysgraphia	2.6%
726	Presyncope	2.6%
727	Dyslalia	2.6%
728	Eye Burns	2.4%
729	Welander Distal Myopathy	2.4%
730	Amaurosis Fugax	2.4%
731	Blindness, Cortical	2.4%
732	Dyscalculia	2.4%
733	Rett Syndrome	2.4%
734	Deafness	2.4%
735	Hearing Loss, Sudden	2.4%
736	Gerstmann Syndrome	2.4%
737	Hearing Loss, Bilateral	2.4%
738	Hearing Loss, High-Frequency	2.4%
739	Hearing Loss, Mixed Conductive-Sensorineural	2.4%
740	Prosopagnosia	2.4%
741	Apraxia, Ideomotor	2.4%
742	Charles Bonnet Syndrome	2.4%
743	Hearing Loss, Unilateral	2.4%
744	Complete Hearing Loss	2.4%
745	Alien Hand Syndrome	2.4%
746	Deaf Mutism	2.4%
747	Rubinstein-Taybi Syndrome	2.3%
748	Dermatomyositis	2.3%
749	Corneal Scar	2.3%
750	Cataplexy	2.3%
751	Aphasia	2.2%
752	Articulation Disorders	2.2%
753	Echolalia	2.2%
754	Stuttering	2.2%
755	Dysphasia	2.2%
756	Muscular Dystrophy, Duchenne	2.2%
757	Retrograde amnesia	2.2%
758	Amnesia, Anterograde	2.2%
759	Mutism	2.1%
760	Selective Mutism	2.1%
761	Dysarthria	2.1%
762	Fragile X Syndrome	2.1%
763	Corneal Perforation	1.9%
764	Alexia, Pure	1.9%
765	Mucopolysaccharidosis II	1.7%

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120141