MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Myotonic Disorders

(UMLS:C0553604)

Definition:: Diseases characterized by MYOTONIA, which may be inherited or acquired. Myotonia may be restricted to certain muscles (e.g., intrinsic hand muscles) or occur as a generalized condition.
UMLS ID:: C0553604
MeSH ID:: D020967

Classification 1:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.651.662

Classification 2:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.668.491.606

Synonym(s)

Myotonic Disorders

Myotonic Disorder

Myotonic disease or syndrome

Myotonic disorder

Myotonic disorders

disease (or disorder); myotonic

myotonic disorder

myotonic disorders

myotonic myopathy

10.

myotonic; disorder

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Acetazolamide	835937	CTD
2	Colchicine	12954545	CTD
3	Ritodrine	3966511	CTD
4	Succinylcholine	5750697	CTD
5	Vincristine	934199	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Myositis	44.8%
2	Fibromyalgia	41.7%
3	Medial Tibial Stress Syndrome	36.1%
4	Mitochondrial Myopathies	35.6%
5	Eosinophilia-Myalgia Syndrome	35.4%
6	Polymyositis	32.8%
7	Isaacs syndrome	31%
8	Familial Periodic Paralysis	29.2%
9	Contracture	28.1%
10	Myofascial Pain Syndromes	27.9%
11	Rhabdomyolysis	27.9%
12	Chronic Fatigue Syndrome	27.4%
13	Muscular Dystrophy	26.5%
14	Orbital Myositis	26.5%
15	Pyomyositis	26.2%
16	Myalgia	24.8%
17	Ischemic contracture	23.6%
18	Arthrogryposis	23.3%
19	Polymyalgia Rheumatica	22.2%
20	Welander Distal Myopathy	21.6%
21	Hypokalemic periodic paralysis	21.4%
22	Compartment syndromes	21.1%
23	Tendinitis	21.1%
24	Motor Neuron Disease	21.1%
25	Tendinopathy	21.1%
26	Neuromuscular Junction Diseases	20.9%
27	Peripheral Nervous System Diseases	20.9%
28	Fibrodysplasia Ossificans Progressiva	20.5%
29	Myoglobinuria	20.5%
30	Myositis Ossificans	20.5%
31	Tenosynovitis	20.5%
32	Hip Contracture	20.3%
33	Mitochondrial Encephalomyopathies	19.9%
34	Muscle Cramp	19%
35	Dermatomyositis	18.4%
36	Muscle Rigidity	18.2%
37	Muscle Spasticity	18.2%
38	Cogwheel Rigidity	18.2%
39	Nuchal Rigidity	18.2%
40	Temporomandibular Joint Dysfunction Syndrome	18.1%
41	Muscular Dystrophy, Duchenne	18%
42	Stiff-Person Syndrome	16.1%
43	Muscle Weakness	16%
44	Complex Regional Pain Syndromes	15.5%
45	Temporomandibular Joint Disorders	15.3%
46	Anterior Compartment Syndrome	15.3%
47	Enthesopathy	15.3%
48	Abdominal Compartment Syndrome	15.3%
49	Brachial Plexus Neuritis	15%
50	Neuralgic Amyotrophy	15%
51	Causalgia	14.7%
52	Bone Diseases	14.6%
53	Fasciitis	14.6%
54	Foot Deformities	14.6%
55	Arthropathy	14.6%
56	Osteoarthropathy, Secondary Hypertrophic	14%
57	Fasciitis, Plantar	14%
58	Tarsal Tunnel Syndrome	13.7%
59	Cauda Equina Syndrome	13.7%
60	Neuritis	13.6%
61	Polyneuritis	13.6%
62	Radiculitis	13.6%
63	Polyneuropathy	13.6%
64	Mononeuritis	13.6%
65	Mononeuropathies	13.6%
66	Brachial Plexus Neuropathies	13.6%
67	Radiculopathy	13.6%
68	Mononeuropathy Multiplex	13.6%
69	Nerve Root Compression	13.6%
70	Musculoskeletal Pain	13.6%
71	Progressive bulbar palsy	13.6%
72	Bulbar palsy	13.6%
73	Spinal Muscular Atrophy	13.5%
74	Progressive Muscular Atrophy	13.5%
75	Myotonic Dystrophy	13.4%
76	Poliomyelitis	13.4%
77	Guillain-Barre Syndrome	13.1%
78	Peripheral Nerve Injuries	12.5%
79	Myasthenia Gravis	12.3%
80	Cranial nerve diseases	12.2%
81	Demyelinating Diseases	12.2%
82	Demyelination	12.2%
83	Chronobiology Disorders	12.2%
84	Dupuytren Contracture	12.2%
85	Polyradiculoneuropathy	12%
86	Polyradiculoneuritis	12%
87	Amyotrophic Lateral Sclerosis	11.5%
88	Jaw Diseases	11.3%
89	Osteoarthritis, Spine	11.3%
90	Osteochondritis	11.1%
91	MELAS Syndrome	11.1%
92	Metatarsalgia	11%
93	Carpal Tunnel Syndrome	11%
94	Reflex Sympathetic Dystrophy	10.9%
95	Cartilage Diseases	10.9%
96	Foot Diseases	10.9%
97	Rheumatism	10.9%
98	Chondromalacia	10.9%
99	Sciatica	10.9%
100	Pectus carinatum	10.8%
101	Myasthenic Syndromes, Congenital	10.3%
102	Botulism	10.2%
103	Diabetic Neuropathies	10.2%
104	Periarthritis	10.2%
105	Diabetic Amyotrophy	10.2%
106	Diabetic Autonomic Neuropathy	10.2%
107	Kearns-Sayre syndrome	10.2%
108	Sciatic Neuropathy	10.1%
109	Ulnar Neuropathies	10.1%
110	Lesion of Sciatic Nerve	10.1%
111	Ulnar Neuritis	10.1%
112	Radial nerve compression	10.1%
113	Radial Tunnel Syndrome	10.1%
114	Peroneal Neuropathies	10.1%
115	Radial Neuropathy	10.1%
116	Median Neuropathy	10.1%
117	Sciatic Nerve Palsy	10.1%
118	Femoral Neuropathy	10.1%
119	Tibial Neuropathy	10.1%
120	Ulnar Nerve Palsy	10.1%
121	Radial nerve palsy	10.1%
122	Neuralgia	10.1%
123	Neuropathic pain	10.1%
124	Platybasia	10.1%
125	Acrodynia	10%
126	Cubital Tunnel Syndrome	9.9%
127	Ankylosing spondylitis	9.8%
128	Gout	9.6%
129	Multiple System Atrophy	9.6%
130	Pectus excavatum	9.6%
131	Rheumatic Fever	9.5%
132	Miller Fisher Syndrome	9.5%
133	Trauma, Nervous System	9.4%
134	Arthritis	9.3%
135	Bone Diseases, Developmental	9.3%
136	Bursitis	9.3%
137	Hyperostosis	9.3%
138	Joint Instability	9.3%
139	Osteitis	9.3%
140	Osteitis Deformans	9.3%
141	Osteochondrosis	9.3%
142	Spinal Diseases	9.3%
143	Synovitis	9.3%
144	Joint laxity	9.3%
145	Polyarthritis	9.3%
146	Frozen shoulder	9.3%
147	Patellofemoral Pain Syndrome	9.3%
148	Lambert-Eaton Myasthenic Syndrome	9.3%
149	Osteoarthritis, Knee	9.2%
150	Talipes	9.1%
151	Nervous System Neoplasms	9.1%
152	Neurologic Manifestations	9.1%
153	Neurotoxicity Syndromes	9.1%
154	Klippel-Feil Syndrome	8.8%
155	Synostosis	8.8%
156	Ocular Motility Disorders	8.7%
157	Cyclophoria	8.7%
158	Encephalomyelitis	8.6%
159	Prion Diseases	8.6%
160	Autonomic Dysreflexia	8.6%
161	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	8.6%
162	Hand-Arm Vibration Syndrome	8.6%
163	Polyradiculopathy	8.4%
164	Restless Legs Syndrome	8.3%
165	Gigantism	8.1%
166	Spinal Neoplasms	8.1%
167	Spondylitis	8.1%
168	Arthritis, Psoriatic	8.1%
169	Rheumatoid Arthritis	8%
170	Juvenile arthritis	8%
171	Spondylarthropathies	7.9%
172	Craniosynostosis	7.8%
173	Syndactyly	7.8%
174	Brachycephaly	7.8%
175	Meningoencephalitis	7.8%
176	Subacute Combined Degeneration	7.8%
177	Congenital clubfoot	7.8%
178	Vertical Talus	7.8%
179	Parkinson Disease	7.7%
180	Thoracic Outlet Syndrome	7.7%
181	Marchiafava-Bignami Disease	7.7%
182	Acrocephalosyndactylia	7.7%
183	Arthritis, Reactive	7.5%
184	Ophthalmoplegic Migraine	7.5%
185	Arthritis, Gouty	7.5%
186	Sleep Wake Disorders	7.4%
187	Craniofacial Dysostosis	7.3%
188	Rheumatoid Nodule	7.3%
189	Bone Diseases, Endocrine	7.3%
190	Neuritis, Autoimmune, Experimental	7.2%
191	Spinal Cord Injuries	7.1%
192	Myasthenia Gravis, Autoimmune, Experimental	7%
193	Bone Diseases, Infectious	7%
194	Bone neoplasms	7%
195	Maxillary Diseases	7%
196	Osteopenia	7%
197	Brain Diseases	7%
198	Dysautonomia	7%
199	Meningitis	7%
200	Movement Disorders	7%
201	Pachymeningitis	7%
202	Spinal Cord Diseases	7%
203	Vagus Nerve Disorder	7%
204	Glossopharyngeal Neuralgia	7%
205	Abducens Nerve Diseases	7%
206	Heavy Metal Poisoning, Nervous System	7%
207	Tauopathies	7%
208	Trochlear Nerve Diseases	7%
209	neurofibroma	6.9%
210	Lewy Body Disease	6.9%
211	Bone Resorption	6.9%
212	Hemarthrosis	6.9%
213	Tietze's Syndrome	6.9%
214	Limb Deformities, Congenital	6.9%
215	Craniofacial Abnormalities	6.9%
216	Aseptic Necrosis of Bone	6.9%
217	Striatonigral Degeneration	6.9%
218	Asterixis	6.8%
219	Ballismus	6.8%
220	Charcot-Marie-Tooth Disease	6.8%
221	Ainhum	6.8%
222	Bunion	6.8%
223	Dysostoses	6.8%
224	Spinal Stenosis	6.8%
225	Spondylosis	6.8%
226	Intervertebral Disc Degeneration	6.8%
227	Sacroiliitis	6.8%
228	Myelitis	6.8%
229	Dandy-Walker Syndrome	6.7%
230	Pneumocephalus	6.7%
231	Poland Syndrome	6.6%
232	Discitis	6.6%
233	Progressive supranuclear palsy	6.2%
234	Leukoencephalitis, Acute Hemorrhagic	6.1%
235	Neuroleptic Malignant Syndrome	6.1%
236	Myelinolysis, Central Pontine	6.1%
237	Felty Syndrome	6.1%
238	Epidural Abscess	6.1%
239	Olfactory Nerve Injuries	6.1%
240	MPTP Poisoning	6%
241	Myelitis, Transverse	6%
242	Shy-Drager Syndrome	5.9%
243	Subdural Effusion	5.9%
244	Parkinsonian Disorders	5.9%
245	Nocturnal Myoclonus Syndrome	5.9%
246	Sleep Disorders, Circadian Rhythm	5.9%
247	Encephalomyelitis, Acute Disseminated	5.8%
248	Goldenhar Syndrome	5.7%
249	Central Nervous System Cysts	5.6%
250	Chondrodysplasia Punctata	5.6%
251	Enchondromatosis	5.6%
252	Lordosis	5.6%
253	Osteosclerosis	5.6%
254	Spondylolysis	5.6%
255	kyphosis	5.6%
256	Kashin-Beck Disease	5.6%
257	Neuromyelitis Optica	5.6%
258	Opsoclonus-Myoclonus Syndrome	5.6%
259	Dystonia Musculorum Deformans	5.6%
260	Acromegaly	5.5%
261	Dyskinesia, Drug-Induced	5.5%
262	Jaw Abnormalities	5.5%
263	Tuberculosis, Spinal	5.5%
264	Central Nervous System Infection	5.5%
265	Optic Neuropathy	5.5%
266	Gastroschisis	5.4%
267	Prognathism	5.4%
268	Brain Injuries	5.4%
269	Brain Neoplasms	5.4%
270	Multiple Sclerosis	5.4%
271	Spinal Cord Neoplasms	5.4%
272	Congenital Hypothyroidism	5.3%
273	Facial Nerve Diseases	5.3%
274	Craniocerebral Trauma	5.3%
275	Parasomnia	5.3%
276	Dyssomnias	5.3%
277	Facial Nerve Injuries	5.2%
278	Mandibulofacial Dysostosis	5.2%
279	Rheumatoid Vasculitis	5.2%
280	Vestibulocochlear Nerve Diseases	5.2%
281	Arthritis, Infectious	5.2%
282	Decerebrate State	5.2%
283	Hemiparesis	5.2%
284	Hydranencephaly	5.2%
285	Meningism	5.2%
286	Multiple Epiphyseal Dysplasia	5.2%
287	Neural Tube Defects	5.2%
288	Osteochondrodysplasias	5.2%
289	Paresis	5.2%
290	Seizures	5.2%
291	Sensation Disorders	5.2%
292	Tethered Cord Syndrome	5.2%
293	Central Nervous System Neoplasms	5.2%
294	Complex partial seizures	5.2%
295	Iniencephaly	5.2%
296	Craniorachischisis	5.2%
297	Exencephaly	5.2%
298	Monoparesis	5.2%
299	Septo-Optic Dysplasia	5.2%
300	Cortical Dysplasia	5.2%
301	Neurogenic Inflammation	5.2%
302	Gait Disorders, Neurologic	5.2%
303	Neuromuscular Manifestations	5.2%
304	Malformations of Cortical Development	5.2%
305	Rubinstein-Taybi Syndrome	5.2%
306	Sweating, Gustatory	5.1%
307	Auriculotemporal Syndrome	5.1%
308	Osteomyelitis	5.1%
309	Osteoporosis	5.1%
310	Periostitis	5.1%
311	Bone Demineralization, Pathologic	5.1%
312	Post-Traumatic Osteoporosis	5.1%
313	Arthritis, Experimental	5.1%
314	Alveolar Bone Loss	5%
315	Amelia	5%
316	Arachnodactyly	5%
317	Ectromelia	5%
318	Femur Head Necrosis	5%
319	Hemimelia	5%
320	Horner Syndrome	5%
321	Phocomelia	5%
322	Sirenomelia	5%
323	Polydactyly	5%
324	Brachydactyly	5%
325	Plagiocephaly	5%
326	Lower Extremity Deformities, Congenital	5%
327	Upper Extremity Deformities, Congenital	5%
328	Osteolysis	5%
329	Melorheostosis	5%
330	Osteopetrosis	5%
331	Spondylolisthesis	5%
332	Meige Syndrome	5%
333	POEMS Syndrome	5%
334	Cerebral Ventriculitis	5%
335	Microcephaly	5%
336	Macrocephaly	5%
337	Leukoencephalopathy, Progressive Multifocal	5%
338	Epilepsy, Post-Traumatic	4.9%
339	Antley-Bixler Syndrome Phenotype	4.9%
340	Akathisia, Drug-Induced	4.9%
341	Scrapie	4.8%
342	Central Cord Syndrome	4.8%
343	Amyloid Neuropathies, Familial	4.7%
344	Limbic Encephalitis	4.7%
345	Presenile dementia	4.7%
346	Senile dementia	4.7%
347	Meningitis, Bacterial	4.7%
348	Meningitis, Fungal	4.7%
349	Chorea	4.7%
350	Huntington Disease	4.6%
351	Nail-Patella Syndrome	4.6%
352	Giant Cell Epulis	4.6%
353	Sicca Syndrome	4.6%
354	Posterior Leukoencephalopathy Syndrome	4.6%
355	Sjogren's Syndrome	4.6%
356	Posterior reversible encephalopathy syndrome	4.6%
357	Akinetic Mutism	4.5%
358	Anoxic Encephalopathy	4.5%
359	Arachnoiditis	4.5%
360	Basal Ganglia Diseases	4.5%
361	Brain Damage, Chronic	4.5%
362	Cerebellar Diseases	4.5%
363	Encephalitis	4.5%
364	Encephalomalacia	4.5%
365	Epilepsy	4.5%
366	Hydrocephalus	4.5%
367	Congenital Hydrocephalus	4.5%
368	Hypothalamic Diseases	4.5%
369	Aseptic Meningitis	4.5%
370	Syringomyelia	4.5%
371	Thalamic Diseases	4.5%
372	Intracranial Hypertension	4.5%
373	Aura	4.5%
374	Leukoencephalopathy	4.5%
375	Essential Tremor	4.5%
376	Neuroaxonal Dystrophies	4.5%
377	Familial Tremor	4.5%
378	Headache Disorders	4.5%
379	Intracranial Hypotension	4.5%
380	Brain Edema	4.5%
381	Brain Hypoxia	4.5%
382	Aqueductal Stenosis	4.5%
383	Pneumorrhachis	4.5%
384	Writer's Cramp	4.5%
385	Lafora Disease	4.5%
386	Unverricht-Lundborg Syndrome	4.5%
387	Brain Abscess	4.5%
388	Ophthalmoplegia	4.5%
389	External Ophthalmoplegia	4.5%
390	Arthralgia	4.5%
391	Polyarthralgia	4.5%
392	Lupus Vasculitis, Central Nervous System	4.4%
393	Porencephaly	4.4%
394	Cerebellar Neoplasms	4.4%
395	Vasculitis, Central Nervous System	4.3%
396	Palatal Neoplasms	4.3%
397	Alstrom Syndrome	4.3%
398	Jet Lag Syndrome	4.3%
399	Micrognathism	4.3%
400	Pierre Robin Syndrome	4.3%
401	Dwarfism	4.3%
402	Pupil Disorders	4.3%
403	Neurobehavioral Manifestations	4.3%
404	Neurofibrosarcoma	4.3%
405	Refsum Disease	4.3%
406	Brain Death	4.2%
407	Coma, Post-Head Injury	4.2%
408	Canavan Disease	4.2%
409	Alexander Disease	4.2%
410	Hip Dislocation	4.2%
411	Osteoporosis, Postmenopausal	4.2%
412	Shoulder Dislocation	4.2%
413	Paraneoplastic Encephalomyelitis	4.2%
414	Hip Dysplasia	4.2%
415	Myoclonic Epilepsy	4.1%
416	Epilepsy, Temporal Lobe	4.1%
417	Epilepsy, Rolandic	4.1%
418	Benign Rolandic Epilepsy	4.1%
419	Uveomeningoencephalitic Syndrome	4.1%
420	Sturge-Weber Syndrome	4.1%
421	Vertigo	4.1%
422	Alcohol-Induced Disorders, Nervous System	4.1%
423	Dementia, Vascular	4.1%
424	Brain Hemorrhage, Traumatic	4.1%
425	Tuberous Sclerosis	4%
426	Joint Tuberculosis	4%
427	Tuberculosis, Osteoarticular	4%
428	Bone Tuberculosis	4%
429	Friedreich Ataxia	4%
430	Creutzfeldt-Jakob disease	4%
431	Basal Ganglia Cerebrovascular Disease	4%
432	Brain Injuries, Diffuse	4%
433	Traumatic Brain Injury	4%
434	Cerebellar Ataxia	4%
435	Supratentorial Neoplasms	4%
436	Torticollis	4%
437	Laryngomalacia	4%
438	Multiple Sclerosis, Chronic Progressive	4%
439	Multiple Sclerosis, Relapsing-Remitting	4%
440	Ataxia Telangiectasia	4%
441	Amblyopia	3.9%
442	Vocal Cord Paralysis	3.9%
443	Paraneoplastic Cerebellar Degeneration	3.9%
444	Cerebrospinal Fluid Otorrhea	3.9%
445	Cerebrospinal Fluid Rhinorrhea	3.9%
446	Gait Ataxia	3.9%
447	Retrognathia	3.8%
448	Eosinophilic Granuloma	3.8%
449	Cockayne Syndrome	3.8%
450	Tuberculosis, Meningeal	3.7%
451	Holoprosencephaly	3.7%
452	Carotid Artery Injuries	3.7%
453	Juvenile Myoclonic Epilepsy	3.7%
454	Myoclonic Epilepsies, Progressive	3.7%
455	Vascular Headaches	3.7%
456	Hypoxia-Ischemia, Brain	3.6%
457	Tardive Dyskinesia	3.6%
458	Persistent Vegetative State	3.6%
459	Voice Disorders	3.5%
460	Voice Disturbance	3.5%
461	Brain Diseases, Metabolic	3.4%
462	Cerebrovascular Disorders	3.4%
463	Optic Atrophy	3.4%
464	Optic Neuritis	3.4%
465	Papilledema	3.4%
466	Strabismus	3.4%
467	Tolosa-Hunt Syndrome	3.4%
468	Cerebrovascular Insufficiency	3.4%
469	Arsenic Poisoning	3.4%
470	Dementia	3.4%
471	Central Nervous System Fungal Infections	3.4%
472	Conus Medullaris Syndrome	3.4%
473	Spinal Cord Vascular Diseases	3.4%
474	Hepatolenticular Degeneration	3.4%
475	Smith-Magenis syndrome	3.4%
476	Osteogenesis Imperfecta	3.4%
477	Facial Injuries	3.4%
478	Facial Neuralgia	3.4%
479	Maxillofacial Abnormalities	3.4%
480	Sleep Talking	3.4%
481	Manganese Poisoning	3.4%
482	Dural Arteriovenous Fistula	3.4%
483	Sleep Disorders, Intrinsic	3.4%
484	Orthostatic intolerance	3.4%
485	Cerebral Palsy	3.4%
486	Epilepsies, Partial	3.4%
487	Epilepsy, Generalized	3.4%
488	Pseudotumor Cerebri	3.4%
489	Hypertensive Encephalopathy	3.4%
490	Simple Partial Seizures	3.4%
491	Epilepsy, Reflex	3.4%
492	Alice in Wonderland Syndrome	3.4%
493	Postural Orthostatic Tachycardia Syndrome	3.4%
494	Headache Disorders, Primary	3.4%
495	Headache Disorders, Secondary	3.4%
496	Medication overuse headache	3.4%
497	Anosmia	3.4%
498	Ataxia	3.4%
499	Athetosis	3.4%
500	Catalepsy	3.4%
501	Dystonia	3.4%
502	Hemiplegia	3.4%
503	Locked-In Syndrome	3.4%
504	Meningeal Neoplasms	3.4%
505	Meningomyelocele	3.4%
506	Muscle Hypertonia	3.4%
507	Muscle hypotonia	3.4%
508	Myoclonus	3.4%
509	Myotonia	3.4%
510	Paraplegia	3.4%
511	Pseudobulbar Palsy	3.4%
512	Quadriplegia	3.4%
513	Spasm	3.4%
514	Spastic Paraplegia	3.4%
515	Status Epilepticus	3.4%
516	Taste Disorders	3.4%
517	Tremor	3.4%
518	Spina Bifida	3.4%
519	Monoplegia	3.4%
520	Hypokinesia	3.4%
521	Paraparesis	3.4%
522	Bradykinesia	3.4%
523	Waxy flexibility	3.4%
524	Action Tremor	3.4%
525	Resting Tremor	3.4%
526	Dysosmia	3.4%
527	Quadriparesis	3.4%
528	Mercury Poisoning, Nervous System	3.4%
529	Olfaction Disorders	3.4%
530	Myokymia	3.4%
531	Lead Poisoning, Nervous System	3.4%
532	Vestibular Neuronitis	3.4%
533	Somatosensory Disorders	3.4%
534	Hyperkinesia	3.4%
535	Intention tremor	3.4%
536	Rickets	3.3%
537	Leukomalacia, Periventricular	3.3%
538	Bronchomalacia	3.3%
539	Tracheomalacia	3.3%
540	Alcohol Withdrawal Seizures	3.3%
541	Mastoiditis	3.3%
542	Petrositis	3.3%
543	Akathisia	3.3%
544	Restlessness	3.3%
545	Psychomotor Agitation	3.3%
546	Basal Cell Nevus Syndrome	3.3%
547	Shoulder Pain	3.3%
548	Diffuse Axonal Injury	3.3%
549	Brain Stem Neoplasms	3.3%
550	Brain Concussion	3.3%
551	Pituitary Adenoma	3.1%
552	Pituitary Neoplasms	3.1%
553	Cleft Palate	3.1%
554	Toxoplasmosis, Cerebral	3.1%
555	Optic Nerve Glioma	3.1%
556	Vertebral Artery Dissection	3.1%
557	Amnesia, Transient Global	3.1%
558	Gait Apraxia	3%
559	Meningitis, Cryptococcal	3%
560	Meningitis, Listeria	3%
561	Meningitis, Haemophilus	3%
562	Meningitis, Pneumococcal	3%
563	Frontotemporal dementia	3%
564	Basal Ganglia Hemorrhage	2.9%
565	Choroid Plexus Papilloma	2.9%
566	Reflex, Abnormal	2.9%
567	Hyporeflexia	2.9%
568	Hyperreflexia	2.9%
569	Pseudohypoparathyroidism	2.9%
570	Vision Disorders	2.8%
571	Metamorphopsia	2.8%
572	Visual Impairment	2.8%
573	Post-Traumatic Headache	2.8%
574	Tension Headache	2.8%
575	Epilepsy, Complex Partial	2.8%
576	Migraine Disorders	2.8%
577	Abdominal Migraine	2.8%
578	Status Migrainosus	2.8%
579	Cervicogenic Headache	2.8%
580	Pituitary Apoplexy	2.8%
581	Optic Neuropathy, Ischemic	2.8%
582	Anterior Ischemic Optic Neuropathy	2.8%
583	Central Nervous System Bacterial Infections	2.8%
584	Facial Hemiatrophy	2.7%
585	Melkersson-Rosenthal Syndrome	2.7%
586	Brain Contusion	2.7%
587	Osteomalacia	2.7%
588	Brain Infarction	2.7%
589	Anisocoria	2.7%
590	Confusion	2.7%
591	Facial paralysis	2.7%
592	Lethargy	2.7%
593	Memory Disorders	2.7%
594	Perceptual Disorders	2.7%
595	Psychomotor Disorders	2.7%
596	Tonic Pupil	2.7%
597	Anhedonia	2.7%
598	Disorientation	2.7%
599	Facial Paresis	2.7%
600	Memory Loss	2.7%
601	Hemisensory Neglect	2.7%
602	Dysacusis	2.7%
603	Subarachnoid Hemorrhage, Traumatic	2.7%
604	Sleep Bruxism	2.7%
605	Carotid Artery, Internal, Dissection	2.7%
606	Anencephaly	2.7%
607	Meningocele	2.7%
608	Muscular Atrophy	2.7%
609	Respiratory Paralysis	2.7%
610	Encephalocele	2.7%
611	Subacute Sclerosing Panencephalitis	2.7%
612	Putaminal Hemorrhage	2.7%
613	Tetany	2.7%
614	Pituitary Diseases	2.7%
615	Infarction, Middle Cerebral Artery	2.6%
616	Infarction, Anterior Cerebral Artery	2.6%
617	Infarction, Posterior Cerebral Artery	2.6%
618	Classical Lissencephalies and Subcortical Band Heterotopias	2.6%
619	Carotid Artery Diseases	2.5%
620	Brain Ischemia	2.5%
621	Esotropia	2.5%
622	Exotropia	2.5%
623	Hypotension, Orthostatic	2.5%
624	Noonan Syndrome	2.5%
625	Sleep Apnea Syndromes	2.5%
626	Cerebrovascular accident	2.5%
627	Kluver-Bucy Syndrome	2.5%
628	Vasospasm, Intracranial	2.5%
629	Spinal Cord Ischemia	2.5%
630	Intracranial Arterial Diseases	2.5%
631	Post-Exercise Hypotension	2.5%
632	Cluster Headache	2.5%
633	Migraine with Aura	2.5%
634	Familial Hemiplegic Migraine	2.5%
635	Chronic Paroxysmal Hemicrania	2.5%
636	SUNCT Syndrome	2.5%
637	Paroxysmal Hemicrania	2.5%
638	Disorders of Excessive Somnolence	2.5%
639	Sleep Initiation and Maintenance Disorders	2.5%
640	Night Terrors	2.5%
641	Somnambulism	2.5%
642	Trigeminal Nerve Disorder	2.5%
643	Transient Insomnia	2.5%
644	Sleep Paralysis	2.5%
645	Chronic Insomnia	2.5%
646	REM Sleep Behavior Disorder	2.5%
647	Hypersomnia	2.5%
648	Dermal Sinus	2.5%
649	Dysgeusia	2.5%
650	Formication	2.5%
651	Hyperalgesia	2.5%
652	Hyperesthesia	2.5%
653	Hypesthesia	2.5%
654	Language Disorders	2.5%
655	Numbness	2.5%
656	Paresthesia	2.5%
657	Paraparesis, Spastic	2.5%
658	Spina Bifida Cystica	2.5%
659	Trismus	2.5%
660	Spina Bifida Occulta	2.5%
661	Epilepsia Partialis Continua	2.5%
662	Hypogeusia	2.5%
663	Meningeal Carcinomatosis	2.5%
664	Brown-Sequard Syndrome	2.5%
665	Lissencephaly	2.5%
666	Polymicrogyria	2.5%
667	Pachygyria	2.5%
668	Schizencephaly	2.5%
669	Lockjaw	2.5%
670	Allodynia	2.5%
671	Lead Poisoning, Nervous System, Childhood	2.5%
672	Lead Poisoning, Nervous System, Adult	2.5%
673	Periventricular Nodular Heterotopia	2.5%
674	Ageusia	2.5%
675	Tuberculosis, Central Nervous System	2.5%
676	Auditory Perceptual Disorders	2.5%
677	Adrenoleukodystrophy	2.5%
678	Cerebral Infarction	2.4%
679	Brain Stem Infarctions	2.4%
680	Acoustic Neuroma	2.4%
681	Giant Cell Arteritis	2.4%
682	Temporal Arteritis	2.4%
683	Alexia	2.3%
684	Dyslexia	2.3%
685	Duane Retraction Syndrome	2.3%
686	Lateral Medullary Syndrome	2.3%
687	Consciousness Disorders	2.3%
688	Mental Retardation	2.3%
689	Depressed Level of Consciousness	2.3%
690	Mental deficiency	2.3%
691	Intellectual Disability	2.3%
692	Mobius Syndrome	2.3%
693	Bell Palsy	2.3%
694	Marfan Syndrome	2.3%
695	Catatonia	2.3%
696	Herpes Zoster Oticus	2.3%
697	Aphonia	2.2%
698	Myotonia Congenita	2.2%
699	Sleep Deprivation	2.2%
700	Dysphonia	2.2%
701	Moyamoya Disease	2.2%
702	West Nile Fever	2.2%
703	Hematoma, Subdural	2.1%
704	Hematoma, Epidural, Cranial	2.1%
705	Empty Sella Syndrome	2.1%
706	Hyperpituitarism	2.1%
707	Hypopituitarism	2.1%
708	Hypophysitis	2.1%
709	Radicular Cyst	2.1%
710	Eye Injuries	2.1%
711	Cerebral Arterial Diseases	2.1%
712	Vertebrobasilar Insufficiency	2.1%
713	Anterior Spinal Artery Syndrome	2.1%
714	Basilar Artery Stenosis	2.1%
715	Vertebral Artery Stenosis	2.1%
716	Sleep Apnea, Obstructive	2.1%
717	Sleep Apnea, Central	2.1%
718	Intracranial Hemorrhage, Hypertensive	2.1%
719	Transient Cerebral Ischemia	2.1%
720	Narcolepsy	2.1%
721	Trigeminal Neuralgia	2.1%
722	Kleine-Levin Syndrome	2.1%
723	Agraphia	2.1%
724	Anomia	2.1%
725	Cluttering	2.1%
726	Language Development Disorders	2.1%
727	Speech Disorders	2.1%
728	Syncope	2.1%
729	Stupor	2.1%
730	Dysgraphia	2.1%
731	Presyncope	2.1%
732	Dyslalia	2.1%
733	Congenital nystagmus	2%
734	Diplopia	2%
735	Scotoma	2%
736	Photophobia	2%
737	Hemifacial Spasm	2%
738	Amaurosis	2%
739	Blindness	2%
740	Reye Syndrome	2%
741	Neuroaspergillosis	2%
742	Optic Atrophy, Hereditary, Leber	2%
743	Intracranial Embolism and Thrombosis	2%
744	Hepatic Encephalopathy	2%
745	Agnosia	2%
746	Apraxias	2%
747	Hallucinations	2%
748	Hemianopsia	2%
749	Hyperacusis	2%
750	Tinnitus	2%
751	Visual Agnosia	2%
752	Anosognosia	2%
753	Wernicke-Korsakoff Syndrome	2%
754	Phonophobia	2%
755	Hearing Loss	2%
756	Sarcopenia	2%
757	Nose Neoplasms	1.9%
758	Neuronal Ceroid-Lipofuscinoses	1.9%
759	Hyperprolactinemia	1.9%
760	Hematoma, Subdural, Intracranial	1.9%
761	Hematoma, Subdural, Chronic	1.9%
762	Hematoma, Subdural, Acute	1.9%
763	Subclavian Steal Syndrome	1.9%
764	Pick Disease of the Brain	1.9%
765	Cataplexy	1.9%
766	Aphasia	1.8%
767	Articulation Disorders	1.8%
768	Echolalia	1.8%
769	Stuttering	1.8%
770	Dysphasia	1.8%
771	Renal Osteodystrophy	1.8%
772	Renal rickets	1.8%
773	Pseudorabies	1.8%
774	Dysarthria	1.7%
775	Aicardi's syndrome	1.7%
776	Hoarseness	1.7%
777	Toxoplasmosis, Congenital	1.7%
778	Amnesia	1.7%
779	Delirium	1.7%
780	Dissociative Amnesia	1.7%
781	Color blindness	1.7%
782	Global Amnesia	1.7%
783	Eye Burns	1.7%
784	Cri-du-Chat Syndrome	1.7%
785	Down Syndrome	1.7%
786	Brain Diseases, Metabolic, Inborn	1.7%
787	Trisomy 21	1.7%
788	Malaria, Cerebral	1.7%
789	Alcohol Withdrawal Delirium	1.7%
790	Meningioma	1.7%
791	Williams Syndrome	1.7%
792	Carotid Stenosis	1.7%
793	Intracranial Aneurysm	1.7%
794	Neurocysticercosis	1.7%
795	Amaurosis Fugax	1.7%
796	Blindness, Cortical	1.7%
797	Dyscalculia	1.7%
798	Intracranial Arteriosclerosis	1.7%
799	Cerebral Atherosclerosis	1.7%
800	Rett Syndrome	1.7%
801	Subarachnoid Hemorrhage	1.7%
802	Cerebral Arteriosclerosis	1.7%
803	Cerebral Hemorrhage	1.7%
804	Neurosyphilis	1.6%
805	Cerebral Thrombosis	1.6%
806	Intracranial Embolism	1.6%
807	Intracranial Thrombosis	1.6%
808	Deafness	1.6%
809	Hearing Loss, Sudden	1.6%
810	Gerstmann Syndrome	1.6%
811	Hearing Loss, Bilateral	1.6%
812	Hearing Loss, High-Frequency	1.6%
813	Hearing Loss, Mixed Conductive-Sensorineural	1.6%
814	Prosopagnosia	1.6%
815	Apraxia, Ideomotor	1.6%
816	Charles Bonnet Syndrome	1.6%
817	Hearing Loss, Unilateral	1.6%
818	Complete Hearing Loss	1.6%
819	Alien Hand Syndrome	1.6%
820	Deaf Mutism	1.6%
821	Mutism	1.5%
822	Selective Mutism	1.5%
823	Cerebral Amyloid Angiopathy	1.5%
824	Sinus Thrombosis, Intracranial	1.5%
825	Prader-Willi Syndrome	1.4%
826	Wernicke Encephalopathy	1.4%
827	AIDS Dementia Complex	1.4%
828	Corneal Scar	1.4%
829	Phantom pain	1.4%
830	Phantom Limb Pain	1.4%
831	Waterhouse-Friderichsen Syndrome	1.4%
832	Lyme Neuroborreliosis	1.4%
833	Alexia, Pure	1.4%
834	Cavernous Sinus Thrombosis	1.4%
835	Sagittal Sinus Thrombosis	1.4%
836	Retrograde amnesia	1.4%
837	Amnesia, Anterograde	1.4%
838	Carotid Artery Thrombosis	1.4%
839	Menkes Kinky Hair Syndrome	1.4%
840	Kernicterus	1.3%
841	Corneal Perforation	1.2%
842	Fragile X Syndrome	1.2%
843	Nelson Syndrome	1.2%
844	Prolactinoma	1.1%
845	Growth Hormone-Secreting Pituitary Adenoma	1.1%
846	Fabry Disease	1.1%
847	Familial Hypophosphatemic Rickets	1%
848	Galactosemias	1%
849	Urea Cycle Disorders, Inborn	1%
850	Tyrosinemias	1%
851	Homocystinuria	0.9%
852	Leigh Disease	0.9%
853	Carbamoyl-Phosphate Synthase I Deficiency Disease	0.8%
854	Mucopolysaccharidosis II	0.8%
855	Glycogen storage disease type II	0.7%
856	Zellweger Syndrome	0.7%
857	Gaucher Disease	0.6%
858	Tay-Sachs Disease	0.6%
859	Niemann-Pick Disease, Type C	0.5%

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