MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Essential Tremor

(UMLS:C0270736)

Definition:: A relatively common disorder characterized by a fairly specific pattern of tremors which are most prominent in the upper extremities and neck, inducing titubations of the head. The tremor is usually mild, but when severe may be disabling. An autosomal dominant pattern of inheritance may occur in some families (i.e., familial tremor). (Mov Disord 1988;13(1):5-10)
UMLS ID:: C0270736
MeSH ID:: D020329

Classification:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.662.350

Synonym(s)

Essential Tremor

Benign essential tremor

Essential tremor

PRESENILE TREMOR SYNDROME

TREMOR ESSENTIAL

Tremor, essential

Tremor, physiological

benign essential tremor

benign essential tremor syndrome

10.

benign essential tremors

11.

essential benign tremor

12.

essential benign tremors

13.

essential tremor

14.

essential tremors

15.

essential; tremor

16.

physiological tremor

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Metoclopramide	FAERS: 122		US FAERS
2	4-hydroxybutyric acid	FAERS: 6		US FAERS
3	Alendronate	FAERS: 6		US FAERS
4	Amiodarone	FAERS: 6		US FAERS
5	Teriparatide	FAERS: 6		US FAERS
6	rofecoxib	FAERS: 6		OFFSIDES US FAERS
7	Sertraline	FAERS: 4		US FAERS
8	Sertraline	FAERS: 4		US FAERS
9	Duloxetine Hydrochloride	FAERS: 3 Canada Vigilance: 1		Canada Vigilance US FAERS
10	NuvaRing	FAERS: 3		US FAERS
11	Vardenafil Dihydrochloride	FAERS: 3		US FAERS
12	palbociclib	FAERS: 3		US FAERS
13	tofacitinib	FAERS: 3		US FAERS
14	2-(Tert-butylamino)-1-(3-chlorophenyl)propan-1-one;hydron;chloride	FAERS: 2		US FAERS
15	Amiodarone	FAERS: 2		US FAERS
16	Amlodipine	FAERS: 2		US FAERS
17	Gadolinium	FAERS: 2		US FAERS
18	Lenalidomide	FAERS: 2 Canada Vigilance: 1		Canada Vigilance US FAERS
19	MDV 3100	FAERS: 2		US FAERS
20	Medroxyprogesterone Acetate	FAERS: 2		US FAERS
21	Pregabalin	FAERS: 2		OFFSIDES US FAERS
22	Quetiapine Fumarate	FAERS: 2		US FAERS
23	Venlafaxine Hydrochloride	FAERS: 2		US FAERS
24	Zoledronic Acid	FAERS: 2		OFFSIDES US FAERS
25	5-(4-ethylpiperazin-1-ylmethyl)pyridin-2-yl)-(5-fluoro-4-(7-fluoro-3-isopropyl-2-methyl-3H-benzimidazol-5-yl)pyrimidin-2-yl)amine	FAERS: 1		US FAERS
26	Acitretin	FAERS: 1		OFFSIDES US FAERS
27	Albuterol	FAERS: 1		US FAERS
28	Anoro Ellipta	FAERS: 1		US FAERS
29	Aripiprazole	FAERS: 1		US FAERS
30	Asenapine	FAERS: 1		US FAERS
31	Aspirin-oxycodone hydrochloride-oxycodone terephthalate combination	FAERS: 1		US FAERS
32	Atorvastatin	FAERS: 1		US FAERS
33	Betaxolol	FAERS: 1		US FAERS
34	Bosentan	FAERS: 1		US FAERS
35	CID 129626832	FAERS: 1		US FAERS
36	Citalopram	FAERS: 1		US FAERS
37	Finasteride	FAERS: 1		US FAERS
38	Formoterol Fumarate	FAERS: 1		US FAERS
39	Insulin Detemir	FAERS: 1		US FAERS
40	Insulin	FAERS: 1		US FAERS
41	LCZ 696	FAERS: 1		US FAERS
42	Lamotrigine	FAERS: 1		US FAERS
43	Levetiracetam	FAERS: 1		OFFSIDES US FAERS
44	Metformin	FAERS: 1		US FAERS
45	Norgestrel	FAERS: 1		US FAERS
46	Nortriptyline	FAERS: 1		US FAERS
47	Olmesartan Medoxomil	FAERS: 1		US FAERS
48	Raloxifene Hydrochloride	FAERS: 1		US FAERS
49	Ranolazine	FAERS: 1		US FAERS
50	Rosuvastatin Calcium	FAERS: 1		US FAERS
51	Sitagliptin Phosphate	FAERS: 1		US FAERS
52	Thyroxine	FAERS: 1		US FAERS
53	Tolvaptan	FAERS: 1		US FAERS
54	Topiramate	FAERS: 1		SIDER US FAERS
55	aliskiren	FAERS: 1		US FAERS
56	apixaban	FAERS: 1		US FAERS
57	apremilast	FAERS: 1		US FAERS
58	bupropion hydrochloride, naltrexone hydrochoride drug combination	FAERS: 1		US FAERS
59	candesartan cilexetil	FAERS: 1		US FAERS
60	etonogestrel	FAERS: 1		US FAERS
61	iloperidone	FAERS: 1		US FAERS
62	riociguat	FAERS: 1		US FAERS
63	ropinirole	FAERS: 1		US FAERS
64	teriflunomide	FAERS: 1		US FAERS
65	ziprasidone	FAERS: 1		US FAERS
66	2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline		19497322	CTD
67	2-chloro-N(6)cyclopentyladenosine		15765150	CTD
68	Alcohols		15765150	CTD
69	Apomorphine		19497322	CTD
70	Baclofen		19497322	CTD
71	Bupropion			OFFSIDES
72	Carbamazepine		19497322	CTD
73	Ciprofloxacin			OFFSIDES
74	Citalopram	Canada Vigilance: 1		Canada Vigilance
75	D-Galactosamine			OFFSIDES
76	Desvenlafaxine Succinate			OFFSIDES
77	Dicyclomine			OFFSIDES
78	Dizocilpine Maleate		15765150 19497322	CTD
79	Fluoxetine			OFFSIDES
80	Gabapentin	Canada Vigilance: 1	View details 10768633 15644468 15765150 19497322	CTD Canada Vigilance
81	Harmaline		19497322	CTD
82	Hydron;carbonate			OFFSIDES
83	Lithium		19497322	CTD
84	Meclizine			OFFSIDES
85	Mesalamine			OFFSIDES
86	Methocarbamol			OFFSIDES
87	Methyltestosterone			OFFSIDES
88	Muscimol		19497322	CTD
89	Phencyclidine		19497322	CTD
90	Pramipexole			OFFSIDES
91	Primidone		15765150 19497322	CTD OFFSIDES
92	Propranolol		View details 6338809 7212666 10768633 15644468 15765150 19497322	CTD OFFSIDES
93	Pyridostigmine Bromide			OFFSIDES
94	Quinidine			OFFSIDES
95	SDZ EAA 494		19497322	CTD
96	Sodium Oxybate		19497322	CTD
97	Theophylline		1946576	CTD
98	Trazodone		3296121	CTD
99	Triiodothyronine			OFFSIDES
100	Valproic Acid		19497322	CTD
101	Zonisamide		17149715 18297619	CTD
102	carbidopa, levodopa drug combination			OFFSIDES
103	entacapone			OFFSIDES
104	miglitol			OFFSIDES
105	repaglinide			OFFSIDES
106	testosterone 17 beta-cypionate			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Writer's Cramp	46.7%
2	Parkinsonian Disorders	40.7%
3	Encephalomyelitis	34.1%
4	Meige Syndrome	32.6%
5	Multiple System Atrophy	31.5%
6	Brain Diseases	31%
7	Meningitis	31%
8	Pachymeningitis	31%
9	Spinal Cord Diseases	31%
10	Asterixis	28.8%
11	Ballismus	28.8%
12	Parkinson Disease	28.6%
13	Meningoencephalitis	27.6%
14	Myelitis	26.7%
15	Lewy Body Disease	24%
16	Striatonigral Degeneration	23.1%
17	Subdural Effusion	23.1%
18	Dystonia Musculorum Deformans	22.4%
19	Central Nervous System Infection	22%
20	Ocular Motility Disorders	21.8%
21	Cyclophoria	21.8%
22	Epidural Abscess	21.7%
23	Chorea	20.5%
24	Prion Diseases	20.5%
25	Akinetic Mutism	20%
26	Anoxic Encephalopathy	20%
27	Arachnoiditis	20%
28	Basal Ganglia Diseases	20%
29	Brain Damage, Chronic	20%
30	Cerebellar Diseases	20%
31	Encephalitis	20%
32	Encephalomalacia	20%
33	Epilepsy	20%
34	Hydrocephalus	20%
35	Congenital Hydrocephalus	20%
36	Hypothalamic Diseases	20%
37	Aseptic Meningitis	20%
38	Syringomyelia	20%
39	Thalamic Diseases	20%
40	Intracranial Hypertension	20%
41	Aura	20%
42	Leukoencephalopathy	20%
43	MPTP Poisoning	20%
44	Neuroaxonal Dystrophies	20%
45	Headache Disorders	20%
46	Intracranial Hypotension	20%
47	Brain Edema	20%
48	Brain Hypoxia	20%
49	Aqueductal Stenosis	20%
50	Pneumorrhachis	20%
51	Pneumocephalus	19.9%
52	Cerebral Ventriculitis	19.6%
53	Torticollis	19.4%
54	Shy-Drager Syndrome	19.3%
55	Progressive supranuclear palsy	19.2%
56	Akathisia, Drug-Induced	19.2%
57	Cranial nerve diseases	18.5%
58	Demyelinating Diseases	18.5%
59	Demyelination	18.5%
60	Neuromuscular Diseases	18.5%
61	Chronobiology Disorders	18.5%
62	Posterior Leukoencephalopathy Syndrome	17.8%
63	Posterior reversible encephalopathy syndrome	17.8%
64	Meningitis, Bacterial	17.4%
65	Meningitis, Fungal	17.4%
66	Marchiafava-Bignami Disease	16.9%
67	Spinal Muscular Atrophy	16.7%
68	Progressive Muscular Atrophy	16.7%
69	Tardive Dyskinesia	16.5%
70	Stiff-Person Syndrome	16.4%
71	Huntington Disease	16.2%
72	Myoclonic Epilepsy	16.1%
73	Epilepsy, Temporal Lobe	16.1%
74	Epilepsy, Rolandic	16.1%
75	Benign Rolandic Epilepsy	16.1%
76	Brain Abscess	16.1%
77	Spinal Cord Injuries	16.1%
78	Dandy-Walker Syndrome	16%
79	Poliomyelitis	15.9%
80	Dyskinesia, Drug-Induced	14.9%
81	Cerebral Palsy	14.8%
82	Epilepsies, Partial	14.8%
83	Epilepsy, Generalized	14.8%
84	Creutzfeldt-Jakob disease	14.8%
85	Pseudotumor Cerebri	14.8%
86	Hypertensive Encephalopathy	14.8%
87	Simple Partial Seizures	14.8%
88	Epilepsy, Reflex	14.8%
89	Basal Ganglia Cerebrovascular Disease	14.8%
90	Headache Disorders, Primary	14.8%
91	Headache Disorders, Secondary	14.8%
92	Medication overuse headache	14.8%
93	Juvenile Myoclonic Epilepsy	14.4%
94	Myoclonic Epilepsies, Progressive	14.4%
95	Motor Neuron Disease	14%
96	Brain Diseases, Metabolic	13.6%
97	Cerebrovascular Disorders	13.6%
98	Epilepsy, Post-Traumatic	13.6%
99	Cerebrovascular Insufficiency	13.6%
100	Dementia	13.6%
101	Central Nervous System Fungal Infections	13.6%
102	Conus Medullaris Syndrome	13.6%
103	Spinal Cord Vascular Diseases	13.6%
104	Dementia, Vascular	13.6%
105	Subacute Combined Degeneration	13.5%
106	Vascular Headaches	13.5%
107	Hypoxia-Ischemia, Brain	13.4%
108	Brain Injuries	13.3%
109	Hepatolenticular Degeneration	13.3%
110	Amyotrophic Lateral Sclerosis	13.3%
111	Brain Neoplasms	13.2%
112	Spinal Cord Neoplasms	13.2%
113	Chronic Fatigue Syndrome	12.9%
114	Tuberculosis, Meningeal	12.8%
115	Trauma, Nervous System	12.8%
116	Neuroleptic Malignant Syndrome	12.6%
117	Myelinolysis, Central Pontine	12.6%
118	Leukoencephalopathy, Progressive Multifocal	12.3%
119	Cerebellar Neoplasms	12.2%
120	Nervous System Neoplasms	12.2%
121	Neurologic Manifestations	12.2%
122	Post-Traumatic Headache	12.2%
123	Tension Headache	12.2%
124	Epilepsy, Complex Partial	12.2%
125	Migraine Disorders	12.2%
126	Neurotoxicity Syndromes	12.2%
127	Abdominal Migraine	12.2%
128	Status Migrainosus	12.2%
129	Cervicogenic Headache	12.2%
130	Lupus Vasculitis, Central Nervous System	12%
131	Limbic Encephalitis	12%
132	Leukomalacia, Periventricular	11.8%
133	Brain Death	11.7%
134	Autonomic Dysreflexia	11.4%
135	Complex Regional Pain Syndromes	11.4%
136	Myelitis, Transverse	10.9%
137	Cluster Headache	10.9%
138	Migraine with Aura	10.9%
139	Familial Hemiplegic Migraine	10.9%
140	Chronic Paroxysmal Hemicrania	10.9%
141	SUNCT Syndrome	10.9%
142	Paroxysmal Hemicrania	10.9%
143	Scrapie	10.9%
144	Central Cord Syndrome	10.9%
145	Lafora Disease	10.9%
146	Unverricht-Lundborg Syndrome	10.9%
147	Meningitis, Cryptococcal	10.7%
148	Presenile dementia	10.7%
149	Senile dementia	10.7%
150	Meningitis, Listeria	10.7%
151	Meningitis, Haemophilus	10.6%
152	Meningitis, Pneumococcal	10.6%
153	Pituitary Diseases	10.6%
154	Friedreich Ataxia	10.6%
155	Toxoplasmosis, Cerebral	10.4%
156	Dysautonomia	10.3%
157	Vagus Nerve Disorder	10.3%
158	Glossopharyngeal Neuralgia	10.3%
159	Abducens Nerve Diseases	10.3%
160	Heavy Metal Poisoning, Nervous System	10.3%
161	Neuromuscular Junction Diseases	10.3%
162	Central Nervous System Bacterial Infections	10.3%
163	Tauopathies	10.3%
164	Trochlear Nerve Diseases	10.3%
165	Peripheral Nervous System Diseases	10.3%
166	Ophthalmoplegic Migraine	10.3%
167	Polyradiculoneuropathy	10.2%
168	Polyradiculoneuritis	10.2%
169	Leukoencephalitis, Acute Hemorrhagic	10.2%
170	Encephalomyelitis, Acute Disseminated	10.2%
171	Amblyopia	10%
172	Basal Ganglia Hemorrhage	9.9%
173	Carotid Artery Diseases	9.9%
174	Brain Ischemia	9.9%
175	Cerebrovascular accident	9.9%
176	Kluver-Bucy Syndrome	9.9%
177	Vasospasm, Intracranial	9.9%
178	Spinal Cord Ischemia	9.9%
179	Intracranial Arterial Diseases	9.9%
180	Pituitary Apoplexy	9.9%
181	Brain Injuries, Diffuse	9.8%
182	Traumatic Brain Injury	9.8%
183	Cerebellar Ataxia	9.7%
184	Supratentorial Neoplasms	9.7%
185	Tuberculosis, Central Nervous System	9.7%
186	Brain Infarction	9.7%
187	Restless Legs Syndrome	9.7%
188	Opsoclonus-Myoclonus Syndrome	9.6%
189	Sleep Wake Disorders	9.3%
190	Persistent Vegetative State	9.3%
191	Putaminal Hemorrhage	9%
192	Subacute Sclerosing Panencephalitis	9%
193	Progressive bulbar palsy	8.9%
194	Bulbar palsy	8.9%
195	Infarction, Middle Cerebral Artery	8.8%
196	Infarction, Anterior Cerebral Artery	8.8%
197	Infarction, Posterior Cerebral Artery	8.8%
198	Carotid Artery Injuries	8.8%
199	Miller Fisher Syndrome	8.8%
200	Brain Hemorrhage, Traumatic	8.8%
201	Pituitary Adenoma	8.7%
202	Pituitary Neoplasms	8.7%
203	Cerebral Infarction	8.6%
204	Brain Stem Infarctions	8.6%
205	Peripheral Nerve Injuries	8.6%
206	Paraneoplastic Cerebellar Degeneration	8.6%
207	Myasthenia Gravis	8.5%
208	Empty Sella Syndrome	8.4%
209	Hyperpituitarism	8.4%
210	Hypopituitarism	8.4%
211	Hypophysitis	8.4%
212	Vasculitis, Central Nervous System	8.4%
213	Causalgia	8.2%
214	Cerebral Arterial Diseases	8.1%
215	Vertebrobasilar Insufficiency	8.1%
216	Lateral Medullary Syndrome	8.1%
217	Anterior Spinal Artery Syndrome	8.1%
218	Basilar Artery Stenosis	8.1%
219	Vertebral Artery Stenosis	8.1%
220	Intracranial Hemorrhage, Hypertensive	8.1%
221	Transient Cerebral Ischemia	8.1%
222	Diffuse Axonal Injury	8%
223	Brain Stem Neoplasms	8%
224	Canavan Disease	8%
225	Alexander Disease	8%
226	Guillain-Barre Syndrome	7.9%
227	Amnesia, Transient Global	7.9%
228	Reflex Sympathetic Dystrophy	7.7%
229	Nocturnal Myoclonus Syndrome	7.7%
230	Moyamoya Disease	7.7%
231	Reye Syndrome	7.4%
232	Neuroaspergillosis	7.4%
233	Intracranial Embolism and Thrombosis	7.4%
234	Hepatic Encephalopathy	7.4%
235	Hyperprolactinemia	7.4%
236	Myopathy	7.3%
237	Optic Neuropathy	7.3%
238	Subclavian Steal Syndrome	7.2%
239	Pick Disease of the Brain	7.2%
240	Olfactory Nerve Injuries	7.2%
241	Choroid Plexus Papilloma	7.2%
242	West Nile Fever	7.2%
243	Sleep Disorders, Circadian Rhythm	7%
244	Facial Nerve Diseases	7%
245	Craniocerebral Trauma	7%
246	Parasomnia	7%
247	Dyssomnias	7%
248	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	6.9%
249	Vestibulocochlear Nerve Diseases	6.8%
250	Decerebrate State	6.8%
251	Hemiparesis	6.8%
252	Hydranencephaly	6.8%
253	Meningism	6.8%
254	Neural Tube Defects	6.8%
255	Paresis	6.8%
256	Seizures	6.8%
257	Sensation Disorders	6.8%
258	Tethered Cord Syndrome	6.8%
259	Central Nervous System Neoplasms	6.8%
260	Complex partial seizures	6.8%
261	Iniencephaly	6.8%
262	Craniorachischisis	6.8%
263	Exencephaly	6.8%
264	Monoparesis	6.8%
265	Septo-Optic Dysplasia	6.8%
266	Cortical Dysplasia	6.8%
267	Neurogenic Inflammation	6.8%
268	Gait Disorders, Neurologic	6.8%
269	Neuromuscular Manifestations	6.8%
270	Malformations of Cortical Development	6.8%
271	Frontotemporal dementia	6.8%
272	Sweating, Gustatory	6.7%
273	Auriculotemporal Syndrome	6.7%
274	Botulism	6.7%
275	Central Nervous System Cysts	6.7%
276	Lambert-Eaton Myasthenic Syndrome	6.7%
277	Neuritis	6.7%
278	Polyneuritis	6.7%
279	Radiculitis	6.7%
280	Polyneuropathy	6.7%
281	Mononeuritis	6.7%
282	Mononeuropathies	6.7%
283	Brachial Plexus Neuropathies	6.7%
284	Radiculopathy	6.7%
285	Mononeuropathy Multiplex	6.7%
286	Nerve Root Compression	6.7%
287	Subarachnoid Hemorrhage, Traumatic	6.6%
288	Carotid Artery, Internal, Dissection	6.6%
289	Multiple Sclerosis	6.6%
290	Mitochondrial Encephalomyopathies	6.6%
291	Brachial Plexus Neuritis	6.5%
292	Neuralgic Amyotrophy	6.5%
293	Brain Contusion	6.5%
294	Ataxia Telangiectasia	6.3%
295	Pseudorabies	6.3%
296	Vertebral Artery Dissection	6.3%
297	Toxoplasmosis, Congenital	6.2%
298	Malaria, Cerebral	6.2%
299	Neuromyelitis Optica	6.2%
300	Carotid Stenosis	6.1%
301	Intracranial Aneurysm	6.1%
302	Neurocysticercosis	6.1%
303	Intracranial Arteriosclerosis	6.1%
304	Cerebral Atherosclerosis	6.1%
305	Subarachnoid Hemorrhage	6.1%
306	Cerebral Arteriosclerosis	6.1%
307	Cerebral Hemorrhage	6.1%
308	Cerebral Thrombosis	6%
309	Intracranial Embolism	6%
310	Intracranial Thrombosis	6%
311	Facial Nerve Injuries	6%
312	Brain Concussion	6%
313	Horner Syndrome	6%
314	Brain Diseases, Metabolic, Inborn	6%
315	Tarsal Tunnel Syndrome	5.9%
316	Cauda Equina Syndrome	5.9%
317	Alice in Wonderland Syndrome	5.9%
318	Neurosyphilis	5.8%
319	Acrodynia	5.7%
320	MELAS Syndrome	5.6%
321	Auditory Perceptual Disorders	5.6%
322	Acromegaly	5.5%
323	Cerebral Amyloid Angiopathy	5.4%
324	Sinus Thrombosis, Intracranial	5.4%
325	Ophthalmoplegia	5.4%
326	External Ophthalmoplegia	5.4%
327	Pupil Disorders	5.4%
328	Neurobehavioral Manifestations	5.4%
329	Adrenoleukodystrophy	5.4%
330	Paraneoplastic Encephalomyelitis	5.2%
331	Charcot-Marie-Tooth Disease	5.1%
332	Myasthenia Gravis, Autoimmune, Experimental	5.1%
333	Coma, Post-Head Injury	5.1%
334	Uveomeningoencephalitic Syndrome	5.1%
335	Cavernous Sinus Thrombosis	5.1%
336	Sagittal Sinus Thrombosis	5.1%
337	Sturge-Weber Syndrome	5%
338	Vertigo	5%
339	Alcohol-Induced Disorders, Nervous System	5%
340	Jet Lag Syndrome	5%
341	Wernicke Encephalopathy	4.9%
342	Sciatic Neuropathy	4.9%
343	Ulnar Neuropathies	4.9%
344	Lesion of Sciatic Nerve	4.9%
345	Ulnar Neuritis	4.9%
346	Radial nerve compression	4.9%
347	Radial Tunnel Syndrome	4.9%
348	Peroneal Neuropathies	4.9%
349	Radial Neuropathy	4.9%
350	Median Neuropathy	4.9%
351	Sciatic Nerve Palsy	4.9%
352	Femoral Neuropathy	4.9%
353	Tibial Neuropathy	4.9%
354	Ulnar Nerve Palsy	4.9%
355	Postural Orthostatic Tachycardia Syndrome	4.9%
356	Radial nerve palsy	4.9%
357	AIDS Dementia Complex	4.9%
358	Multiple Sclerosis, Chronic Progressive	4.9%
359	Multiple Sclerosis, Relapsing-Remitting	4.9%
360	Lyme Neuroborreliosis	4.9%
361	Carotid Artery Thrombosis	4.8%
362	Giant Cell Arteritis	4.7%
363	Temporal Arteritis	4.7%
364	Myotonia Congenita	4.6%
365	Waterhouse-Friderichsen Syndrome	4.6%
366	Refsum Disease	4.6%
367	Cerebrospinal Fluid Otorrhea	4.6%
368	Cerebrospinal Fluid Rhinorrhea	4.6%
369	Neuritis, Autoimmune, Experimental	4.6%
370	Gait Ataxia	4.6%
371	Myositis	4.5%
372	Optic Atrophy	4.5%
373	Optic Neuritis	4.5%
374	Papilledema	4.5%
375	Strabismus	4.5%
376	Tolosa-Hunt Syndrome	4.5%
377	Isaacs syndrome	4.5%
378	Arsenic Poisoning	4.5%
379	Myotonic Disorders	4.5%
380	Myasthenic Syndromes, Congenital	4.5%
381	Vocal Cord Paralysis	4.5%
382	Carpal Tunnel Syndrome	4.5%
383	Hematoma, Subdural	4.5%
384	Hematoma, Epidural, Cranial	4.5%
385	neurofibroma	4.5%
386	Diabetic Neuropathies	4.4%
387	Facial Injuries	4.4%
388	Facial Neuralgia	4.4%
389	Diabetic Amyotrophy	4.4%
390	Diabetic Autonomic Neuropathy	4.4%
391	Sleep Talking	4.4%
392	Manganese Poisoning	4.4%
393	Sleep Disorders, Intrinsic	4.4%
394	Orthostatic intolerance	4.4%
395	Sciatica	4.4%
396	Tuberous Sclerosis	4.4%
397	Anosmia	4.4%
398	Ataxia	4.4%
399	Athetosis	4.4%
400	Catalepsy	4.4%
401	Dystonia	4.4%
402	Hemiplegia	4.4%
403	Locked-In Syndrome	4.4%
404	Meningeal Neoplasms	4.4%
405	Meningomyelocele	4.4%
406	Muscle Hypertonia	4.4%
407	Muscle hypotonia	4.4%
408	Myoclonus	4.4%
409	Myotonia	4.4%
410	Neuralgia	4.4%
411	Paraplegia	4.4%
412	Pseudobulbar Palsy	4.4%
413	Quadriplegia	4.4%
414	Spasm	4.4%
415	Spastic Paraplegia	4.4%
416	Status Epilepticus	4.4%
417	Taste Disorders	4.4%
418	Tremor	4.4%
419	Spina Bifida	4.4%
420	Monoplegia	4.4%
421	Hypokinesia	4.4%
422	Paraparesis	4.4%
423	Bradykinesia	4.4%
424	Waxy flexibility	4.4%
425	Action Tremor	4.4%
426	Resting Tremor	4.4%
427	Dysosmia	4.4%
428	Quadriparesis	4.4%
429	Mercury Poisoning, Nervous System	4.4%
430	Olfaction Disorders	4.4%
431	Myokymia	4.4%
432	Lead Poisoning, Nervous System	4.4%
433	Vestibular Neuronitis	4.4%
434	Somatosensory Disorders	4.4%
435	Neuropathic pain	4.4%
436	Hyperkinesia	4.4%
437	Intention tremor	4.4%
438	Kernicterus	4.3%
439	Voice Disorders	4.2%
440	Voice Disturbance	4.2%
441	Nelson Syndrome	4.1%
442	Polyradiculopathy	4.1%
443	Smith-Magenis syndrome	4.1%
444	Hematoma, Subdural, Intracranial	4%
445	Hematoma, Subdural, Chronic	4%
446	Hematoma, Subdural, Acute	4%
447	Cubital Tunnel Syndrome	4%
448	Dural Arteriovenous Fistula	4%
449	Myotonic Dystrophy	3.9%
450	Akathisia	3.8%
451	Restlessness	3.8%
452	Psychomotor Agitation	3.8%
453	Alcohol Withdrawal Seizures	3.7%
454	Prolactinoma	3.7%
455	Growth Hormone-Secreting Pituitary Adenoma	3.7%
456	Hand-Arm Vibration Syndrome	3.6%
457	Gait Apraxia	3.5%
458	Vision Disorders	3.5%
459	Metamorphopsia	3.5%
460	Visual Impairment	3.5%
461	Galactosemias	3.5%
462	Urea Cycle Disorders, Inborn	3.5%
463	Tyrosinemias	3.5%
464	Fibromyalgia	3.4%
465	Optic Neuropathy, Ischemic	3.4%
466	Anterior Ischemic Optic Neuropathy	3.4%
467	Medial Tibial Stress Syndrome	3.4%
468	Fabry Disease	3.4%
469	Facial Hemiatrophy	3.4%
470	Melkersson-Rosenthal Syndrome	3.4%
471	Mitochondrial Myopathies	3.4%
472	Thoracic Outlet Syndrome	3.4%
473	Anisocoria	3.4%
474	Confusion	3.4%
475	Facial paralysis	3.4%
476	Lethargy	3.4%
477	Memory Disorders	3.4%
478	Muscle Cramp	3.4%
479	Perceptual Disorders	3.4%
480	Psychomotor Disorders	3.4%
481	Tonic Pupil	3.4%
482	Eosinophilia-Myalgia Syndrome	3.4%
483	Anhedonia	3.4%
484	Disorientation	3.4%
485	Facial Paresis	3.4%
486	Memory Loss	3.4%
487	Hemisensory Neglect	3.4%
488	Dysacusis	3.4%
489	Optic Nerve Glioma	3.4%
490	Sleep Bruxism	3.3%
491	Reflex, Abnormal	3.3%
492	Hyporeflexia	3.3%
493	Hyperreflexia	3.3%
494	Anencephaly	3.3%
495	Meningocele	3.3%
496	Muscular Atrophy	3.3%
497	Respiratory Paralysis	3.3%
498	Encephalocele	3.3%
499	Esotropia	3.3%
500	Exotropia	3.3%
501	Hypotension, Orthostatic	3.3%
502	Sleep Apnea Syndromes	3.3%
503	Polymyositis	3.3%
504	Post-Exercise Hypotension	3.3%
505	Tetany	3.3%
506	Disorders of Excessive Somnolence	3.3%
507	Sleep Initiation and Maintenance Disorders	3.3%
508	Night Terrors	3.3%
509	Somnambulism	3.3%
510	Trigeminal Nerve Disorder	3.3%
511	Transient Insomnia	3.3%
512	Sleep Paralysis	3.3%
513	Chronic Insomnia	3.3%
514	REM Sleep Behavior Disorder	3.3%
515	Hypersomnia	3.3%
516	Dermal Sinus	3.2%
517	Dysgeusia	3.2%
518	Formication	3.2%
519	Hyperalgesia	3.2%
520	Hyperesthesia	3.2%
521	Hypesthesia	3.2%
522	Language Disorders	3.2%
523	Numbness	3.2%
524	Paresthesia	3.2%
525	Paraparesis, Spastic	3.2%
526	Spina Bifida Cystica	3.2%
527	Trismus	3.2%
528	Spina Bifida Occulta	3.2%
529	Epilepsia Partialis Continua	3.2%
530	Hypogeusia	3.2%
531	Meningeal Carcinomatosis	3.2%
532	Brown-Sequard Syndrome	3.2%
533	Lissencephaly	3.2%
534	Polymicrogyria	3.2%
535	Pachygyria	3.2%
536	Schizencephaly	3.2%
537	Lockjaw	3.2%
538	Allodynia	3.2%
539	Lead Poisoning, Nervous System, Childhood	3.2%
540	Lead Poisoning, Nervous System, Adult	3.2%
541	Periventricular Nodular Heterotopia	3.2%
542	Ageusia	3.2%
543	Alstrom Syndrome	3.1%
544	Homocystinuria	3.1%
545	Leigh Disease	3%
546	Classical Lissencephalies and Subcortical Band Heterotopias	2.9%
547	Menkes Kinky Hair Syndrome	2.9%
548	Amyloid Neuropathies, Familial	2.8%
549	Duane Retraction Syndrome	2.7%
550	Consciousness Disorders	2.7%
551	Mental Retardation	2.7%
552	Muscle Weakness	2.7%
553	Depressed Level of Consciousness	2.7%
554	Mental deficiency	2.7%
555	Intellectual Disability	2.7%
556	Carbamoyl-Phosphate Synthase I Deficiency Disease	2.7%
557	Mobius Syndrome	2.7%
558	Bell Palsy	2.7%
559	Sleep Apnea, Obstructive	2.7%
560	Sleep Apnea, Central	2.7%
561	Narcolepsy	2.7%
562	Trigeminal Neuralgia	2.7%
563	Kleine-Levin Syndrome	2.7%
564	Catatonia	2.7%
565	Agraphia	2.7%
566	Alexia	2.7%
567	Anomia	2.7%
568	Cluttering	2.7%
569	Language Development Disorders	2.7%
570	Speech Disorders	2.7%
571	Syncope	2.7%
572	Stupor	2.7%
573	Dysgraphia	2.7%
574	Dyslexia	2.7%
575	Presyncope	2.7%
576	Dyslalia	2.7%
577	Herpes Zoster Oticus	2.7%
578	Familial Periodic Paralysis	2.7%
579	Aphonia	2.6%
580	Sleep Deprivation	2.6%
581	Dysphonia	2.6%
582	Acoustic Neuroma	2.6%
583	Eye Injuries	2.6%
584	Neurofibrosarcoma	2.5%
585	Muscular Dystrophy	2.5%
586	Congenital nystagmus	2.5%
587	Orbital Myositis	2.5%
588	Diplopia	2.5%
589	Muscle Rigidity	2.5%
590	Muscle Spasticity	2.5%
591	Scotoma	2.5%
592	Photophobia	2.5%
593	Cogwheel Rigidity	2.5%
594	Hemifacial Spasm	2.5%
595	Amaurosis	2.5%
596	Blindness	2.5%
597	Nuchal Rigidity	2.5%
598	Pyomyositis	2.5%
599	Agnosia	2.4%
600	Apraxias	2.4%
601	Hallucinations	2.4%
602	Hemianopsia	2.4%
603	Hyperacusis	2.4%
604	Tinnitus	2.4%
605	Visual Agnosia	2.4%
606	Anosognosia	2.4%
607	Wernicke-Korsakoff Syndrome	2.4%
608	Phonophobia	2.4%
609	Hearing Loss	2.4%
610	Sarcopenia	2.4%
611	Cataplexy	2.4%
612	Aphasia	2.4%
613	Articulation Disorders	2.4%
614	Echolalia	2.4%
615	Stuttering	2.4%
616	Dysphasia	2.4%
617	Glycogen storage disease type II	2.4%
618	Dysarthria	2.3%
619	Optic Atrophy, Hereditary, Leber	2.2%
620	Zellweger Syndrome	2.2%
621	Myalgia	2.2%
622	Kearns-Sayre syndrome	2.2%
623	Neuronal Ceroid-Lipofuscinoses	2.2%
624	Eye Burns	2.1%
625	Welander Distal Myopathy	2%
626	Amaurosis Fugax	2%
627	Blindness, Cortical	2%
628	Dyscalculia	2%
629	Rett Syndrome	2%
630	Gaucher Disease	2%
631	Deafness	2%
632	Hearing Loss, Sudden	2%
633	Gerstmann Syndrome	2%
634	Hearing Loss, Bilateral	2%
635	Hearing Loss, High-Frequency	2%
636	Hearing Loss, Mixed Conductive-Sensorineural	2%
637	Prosopagnosia	2%
638	Apraxia, Ideomotor	2%
639	Charles Bonnet Syndrome	2%
640	Hearing Loss, Unilateral	2%
641	Complete Hearing Loss	2%
642	Alien Hand Syndrome	2%
643	Deaf Mutism	2%
644	Amnesia	2%
645	Delirium	2%
646	Dissociative Amnesia	2%
647	Color blindness	2%
648	Global Amnesia	2%
649	Cri-du-Chat Syndrome	2%
650	Down Syndrome	2%
651	Trisomy 21	2%
652	POEMS Syndrome	2%
653	Meningioma	2%
654	Williams Syndrome	2%
655	Microcephaly	2%
656	Macrocephaly	2%
657	Hypokalemic periodic paralysis	1.9%
658	Porencephaly	1.9%
659	Aicardi's syndrome	1.9%
660	Tay-Sachs Disease	1.9%
661	Hoarseness	1.9%
662	Cockayne Syndrome	1.9%
663	Alcohol Withdrawal Delirium	1.9%
664	Mutism	1.8%
665	Selective Mutism	1.8%
666	Niemann-Pick Disease, Type C	1.8%
667	Alexia, Pure	1.7%
668	Dermatomyositis	1.7%
669	Corneal Scar	1.7%
670	Holoprosencephaly	1.7%
671	Prader-Willi Syndrome	1.6%
672	Muscular Dystrophy, Duchenne	1.6%
673	Phantom pain	1.6%
674	Phantom Limb Pain	1.6%
675	Retrograde amnesia	1.6%
676	Amnesia, Anterograde	1.6%
677	Corneal Perforation	1.5%
678	Fragile X Syndrome	1.3%
679	Rubinstein-Taybi Syndrome	1.2%
680	Mucopolysaccharidosis II	0.9%

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