MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

granulosa cell tumor

(UMLS:C0018206)

Definition:: A neoplasm composed entirely of GRANULOSA CELLS, occurring mostly in the OVARY. In the adult form, it may contain some THECA CELLS. This tumor often produces ESTRADIOL and INHIBIN. The excess estrogen exposure can lead to other malignancies in women and PRECOCIOUS PUBERTY in girls. In rare cases, granulosa cell tumors have been identified in the TESTES.
UMLS ID:: C0018206
MeSH ID:: D006106

Classification 1:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.475.750.656|C04.588.322.455.398

Classification 2:

Name:

Female Urogenital Diseases and Pregnancy Complications
MeSH Tree Number(s):: C13.351.500.056.630.705.398|C13.351.937.418.685.398

Classification 3:

Name:

Endocrine System Diseases
MeSH Tree Number(s):: C19.344.410.398|C19.391.630.705.398

Synonym(s)

granulosa cell tumor

Granulosa Cell Neoplasm

Granulosa Cell Tumor

Granulosa cell tumor

Granulosa cell tumor NOS

Granulosa cell tumor, NOS

Granulosa cell tumor, adult type

Granulosa cell tumour

Granulosa cell tumour NOS

10.

Granulosa cell tumour, NOS

11.

cell granulosa tumor

12.

cells granulosa tumor

13.

granulosa cell tumors

14.

granulosa cell tumour

15.

granulosa cell; tumor

16.

tumor cell granulosa

17.

tumor; granulosa cell

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Benzene		12748714	CTD
2	Isoniazid		6248561	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Carcinoma, Ovarian Epithelial	45.9%
2	Carcinoma, Endometrioid	33%
3	Oophoritis	23.5%
4	Parathyroid Neoplasms	23.2%
5	Thyroid Neoplasm	23.2%
6	Thyroid carcinoma	23.2%
7	Corpus Luteum Cyst	22.2%
8	Ovarian Cysts	22.2%
9	Adrenal Gland Neoplasms	21.3%
10	Ovarian Hyperstimulation Syndrome	20.7%
11	Multiple Endocrine Neoplasia	20.3%
12	Testicular Neoplasms	18.6%
13	Anovulation	18.4%
14	Pancreatic Neoplasm	17.9%
15	Fallopian Tube Neoplasms	17.3%
16	Uterine Neoplasms	17%
17	Vaginal Neoplasms	17%
18	Vulvar Neoplasms	17%
19	Uterine Cancer	17%
20	Thyroid Nodule	14.9%
21	Polycystic Ovary Syndrome	14.6%
22	Leydig Cell Tumor	14.5%
23	Pituitary Adenoma	14.5%
24	Pituitary Neoplasms	14.5%
25	Prolactinoma	13.5%
26	Growth Hormone-Secreting Pituitary Adenoma	13.5%
27	Urologic Neoplasms	13.2%
28	Multiple Endocrine Neoplasia Type 1	12.7%
29	Carcinoma, Pancreatic Ductal	12.5%
30	Hermaphroditism	11.7%
31	Disorders of Sex Development	11.7%
32	Salpingitis	11.4%
33	Adrenocortical carcinoma	11.4%
34	Pregnancy Complications, Neoplastic	11.2%
35	Endometrial Neoplasms	11.2%
36	Endometritis	11.1%
37	Urologic Diseases	11%
38	Endometriosis	10.8%
39	Uterine Diseases	10.8%
40	Vaginal Diseases	10.8%
41	Vulvar Diseases	10.8%
42	Endometrioma	10.8%
43	Endometrial Stromal Sarcoma	10.6%
44	Neoplasms, Neuroepithelial	10.1%
45	Gliomatosis cerebri	10.1%
46	Nephroblastoma	9.9%
47	Urogenital Abnormalities	9.9%
48	Hypogonadism	9.8%
49	Delayed Puberty	9.8%
50	Precocious Puberty	9.8%
51	Hypogonadotropic hypogonadism	9.8%
52	Testotoxicosis	9.8%
53	Trophoblastic Neoplasms	9.8%
54	Neuroectodermal Tumors	9.7%
55	Meningioma	9.7%
56	Vipoma	9.6%
57	Infertility	9.5%
58	Adnexitis	9.4%
59	Pelvic Inflammatory Disease	9.4%
60	Premature Menopause	9.4%
61	insulinoma	9.4%
62	Abdominal Neoplasms	9.3%
63	Head and Neck Neoplasms	9.3%
64	leukemia	9.3%
65	Neoplasms, Germ Cell and Embryonal	9.3%
66	Neoplasms, Glandular and Epithelial	9.3%
67	Soft Tissue Neoplasms	9.3%
68	Thoracic Neoplasms	9.3%
69	Germ Cell Cancer	9.3%
70	Gastrinoma	9.1%
71	Glucagonoma	9.1%
72	Adrenal Gland Diseases	9%
73	Parathyroid Diseases	9%
74	Thyroid Diseases	9%
75	Bladder Neoplasm	9%
76	Kidney Neoplasm	9%
77	Ureteral Neoplasms	9%
78	Urethral Neoplasms	9%
79	Nelson Syndrome	9%
80	Mesoblastic Nephroma	8.7%
81	Carcinoma 256, Walker	8.7%
82	Testicular Diseases	8.7%
83	melanoma	8.6%
84	Hamartoma	8.6%
85	Neoplasms, Hormone-Dependent	8.6%
86	Neoplasms, Multiple Primary	8.6%
87	Paraneoplastic Syndromes	8.6%
88	Precancerous Conditions	8.6%
89	Neoplasms, Second Primary	8.6%
90	Medulloblastoma	8.5%
91	Digestive System Neoplasms	8.4%
92	Eye Neoplasms	8.4%
93	Nervous System Neoplasms	8.4%
94	Carcinoma, Lobular	8.4%
95	Bone neoplasms	8.3%
96	Skin Neoplasms	8.3%
97	Hematologic Neoplasms	8.3%
98	Melanoma, Experimental	8.2%
99	Histiocytic Disorders, Malignant	8.2%
100	Splenic Neoplasms	8.2%
101	Carcinosarcoma	8.1%
102	Hemangiosarcoma	8.1%
103	lymphangiosarcoma	8.1%
104	Acanthoma	8.1%
105	Paraneoplastic Encephalomyelitis	8.1%
106	Leukemia, Experimental	8%
107	Mammary Neoplasms, Experimental	8%
108	Bone Diseases, Endocrine	8%
109	Pregnancy Complications	8%
110	Peritoneal Neoplasms	7.9%
111	Diabetes Mellitus	7.9%
112	Pituitary Diseases	7.9%
113	Sexually Transmitted Diseases	7.8%
114	Denys-Drash Syndrome	7.8%
115	Composite Lymphoma	7.8%
116	Genital Herpes	7.6%
117	Genital Neoplasms, Female	7.6%
118	Cyst	7.6%
119	Neoplastic Processes	7.6%
120	Neoplastic Syndromes, Hereditary	7.6%
121	Neoplasms, Experimental	7.5%
122	Kallmann Syndrome	7.4%
123	Choriocarcinoma	7.3%
124	Carcinoma, Ehrlich Tumor	7.3%
125	Dermoid Cyst	7.3%
126	Carcinoma, Lewis Lung	7.3%
127	Lymphoma	7.3%
128	Uterine Inversion	7.3%
129	Leukemia, Radiation-Induced	7.3%
130	Gestational Diabetes	7.2%
131	Thymoma	7.2%
132	Leukemia, Plasma Cell	7.2%
133	Adenoma, Acidophil	7.1%
134	Ganglioneuroma	7.1%
135	Glioma	7.1%
136	Malignant Glioma	7.1%
137	Dwarfism	7.1%
138	Renal Cell Carcinoma	7.1%
139	Papillary Renal Cell Carcinoma	7.1%
140	Retinoblastoma	7%
141	Diabetes Insipidus	7%
142	Gonadal Dysgenesis	6.9%
143	Adrenogenital Syndrome	6.9%
144	Ovotesticular Disorders of Sex Development	6.9%
145	Klinefelter Syndrome	6.7%
146	Bladder Exstrophy	6.7%
147	Epispadias	6.7%
148	Neoplasms, Radiation-Induced	6.7%
149	Tuberculosis, Renal	6.7%
150	Tuberous Sclerosis	6.7%
151	Vulvovaginitis	6.6%
152	Tracheal Neoplasms	6.6%
153	Parametritis	6.5%
154	Uterine Rupture	6.5%
155	Hyperandrogenism	6.5%
156	Sarcoma, Experimental	6.5%
157	Basal cell carcinoma	6.4%
158	Carcinoma, Papillary	6.4%
159	Squamous cell carcinoma	6.4%
160	Chondrosarcoma	6.4%
161	Craniopharyngioma	6.4%
162	Cystadenoma	6.4%
163	leiomyosarcoma	6.4%
164	liposarcoma	6.4%
165	Mesothelioma	6.4%
166	synovial sarcoma	6.4%
167	Neuroectodermal Tumor, Melanotic	6.4%
168	Angiomyolipoma	6.4%
169	Clear Cell Sarcoma of Soft Tissue	6.4%
170	Alveolar Soft Part Sarcoma	6.4%
171	Neuroendocrine Tumors	6.4%
172	Sarcoma, Myeloid	6.4%
173	Carcinoma, Basal Cell	6.4%
174	Carcinoid Tumor	6.4%
175	Neurilemmoma	6.4%
176	Hutchinson's Melanotic Freckle	6.4%
177	Melanoma, Amelanotic	6.4%
178	Acoustic Neuroma	6.3%
179	Endometrial Hyperplasia	6.1%
180	Pyometra	6.1%
181	Vaginitis	6.1%
182	Vulvitis	6.1%
183	Vaginal Discharge	6.1%
184	Vulvodynia	6.1%
185	Esophageal Neoplasms	5.9%
186	Endocrine Gland Neoplasms	5.9%
187	Urinary Bladder Diseases	5.8%
188	Kidney Diseases	5.8%
189	Ureteral Diseases	5.8%
190	Urethral Diseases	5.8%
191	Urination Disorders	5.8%
192	Urolithiasis	5.8%
193	Multicystic Dysplastic Kidney	5.8%
194	Astrocytoma	5.7%
195	Ependymoma	5.7%
196	oligodendroglioma	5.7%
197	Ganglioglioma	5.7%
198	gliosarcoma	5.7%
199	Anaplastic astrocytoma	5.7%
200	Anaplastic Oligodendroglioma	5.7%
201	Leukemia L1210	5.7%
202	Leukemia P388	5.7%
203	Cystadenocarcinoma	5.6%
204	Fibrosarcoma	5.6%
205	Osteosarcoma	5.6%
206	Mucoepidermoid Carcinoma	5.6%
207	ovarian neoplasm	5.6%
208	Adenoma	5.5%
209	Ameloblastoma	5.5%
210	Angiokeratoma	5.5%
211	Carcinoma	5.5%
212	Chordoma	5.5%
213	Hemangioma	5.5%
214	hemangiopericytoma	5.5%
215	Lymphangioma	5.5%
216	Mesenchymoma	5.5%
217	Nevus	5.5%
218	Retroperitoneal Neoplasms	5.5%
219	Teratoma	5.5%
220	Hepatoblastoma	5.5%
221	Mixed Tumor, Mullerian	5.5%
222	Germinoma	5.5%
223	Teratocarcinoma	5.5%
224	Angiofibroma	5.5%
225	Sarcoma	5.5%
226	Epithelioma	5.5%
227	Diabetic Nephropathy	5.5%
228	Vesicovaginal Fistula	5.5%
229	Basal Cell Nevus Syndrome	5.4%
230	Optic Nerve Glioma	5.4%
231	Congenital Hypothyroidism	5.4%
232	Pruritus Vulvae	5.4%
233	Uterine hemorrhage	5.4%
234	Vaginal Fistula	5.4%
235	Liver Neoplasms, Experimental	5.4%
236	Anuria	5.4%
237	Ureterolithiasis	5.4%
238	Nephrolithiasis	5.4%
239	Uterine Prolapse	5.3%
240	Vaginal Prolapse	5.3%
241	Malignant Carcinoid Syndrome	5.3%
242	Orchitis	5.3%
243	Urinary tract infection	5.2%
244	Adenofibroma	5.2%
245	Fibroadenoma	5.2%
246	Malignant Fibrous Histiocytoma	5.2%
247	Horseshoe Kidney	5.2%
248	Hepatocellular Adenoma	5.2%
249	Lymphomatoid Granulomatosis	5.2%
250	Lymphangioleiomyomatosis	5.2%
251	Adrenal Cortex Diseases	5.1%
252	Euthyroid Sick Syndromes	5.1%
253	Goiter	5.1%
254	Hyperparathyroidism	5.1%
255	Hyperthyroidism	5.1%
256	Hyperthyroxinemia	5.1%
257	Hypoparathyroidism	5.1%
258	Hypothyroidism	5.1%
259	Thyroiditis	5.1%
260	Secondary hypothyroidism	5.1%
261	Primary Hyperthyroidism	5.1%
262	Primary Hypothyroidism	5.1%
263	Glioblastoma	5%
264	Neuroblastoma	5%
265	Glioblastoma Multiforme	5%
266	Neurofibrosarcoma	4.9%
267	Mouth Neoplasms	4.9%
268	Central Nervous System Neoplasms	4.9%
269	Vascular Neoplasms	4.9%
270	Thymus Neoplasms	4.9%
271	Plasmacytoma	4.9%
272	Urinary Bladder Fistula	4.9%
273	Malignant histiocytosis	4.9%
274	Breast Neoplasms, Male	4.9%
275	Histiocytic sarcoma	4.9%
276	Triple Negative Breast Neoplasms	4.9%
277	Sarcoma 180	4.8%
278	Turner Syndrome	4.8%
279	Bowen's Disease	4.8%
280	Paraganglioma	4.8%
281	Rhabdomyosarcoma	4.8%
282	Giant Cell Tumor of Bone	4.8%
283	Dyspareunia	4.8%
284	Gonadal Disorders	4.8%
285	Hypospadias	4.7%
286	Erythroplasia	4.7%
287	Follicular cyst	4.7%
288	Mucocele	4.7%
289	Pilonidal Cyst	4.7%
290	Thyroglossal Cyst	4.7%
291	Synovial Cyst	4.7%
292	Aberrant Crypt Foci	4.7%
293	Ganglioneuroblastoma	4.6%
294	Graves Disease	4.6%
295	Leukoplakia, Oral	4.6%
296	Paraneoplastic Cerebellar Degeneration	4.5%
297	Adenomatous Polyposis Coli	4.5%
298	Empty Sella Syndrome	4.5%
299	Hyperpituitarism	4.5%
300	Hypopituitarism	4.5%
301	Hypophysitis	4.5%
302	Uterine Cervical Incompetence	4.4%
303	Dermatofibrosarcoma	4.4%
304	Dermatofibrosarcoma Protuberans	4.4%
305	Gastrointestinal Neoplasms	4.4%
306	Genital Neoplasms, Male	4.4%
307	Liver neoplasms	4.4%
308	Uveal Neoplasms	4.4%
309	Bladder neck obstruction	4.4%
310	Carcinoid Heart Disease	4.4%
311	Sebaceous Gland Neoplasms	4.3%
312	Spinal Neoplasms	4.3%
313	Bone Marrow Neoplasms	4.3%
314	Hodgkin Disease	4.3%
315	Lymphoma, Non-Hodgkin	4.3%
316	Ovarian Diseases	4.3%
317	Cryptorchidism	4.3%
318	Hydatidiform Mole	4.2%
319	Leukoplakia	4.1%
320	Lymphocele	4.1%
321	Pancreatic Cyst	4.1%
322	Limbic Encephalitis	4.1%
323	Candidiasis, Vulvovaginal	4.1%
324	Barrett Esophagus	4.1%
325	Breast Cyst	4.1%
326	Actinic keratosis	4.1%
327	Mediastinal Cyst	4.1%
328	Neoplasm Invasiveness	4.1%
329	Neoplasm Metastasis	4.1%
330	Neoplasm Recurrence, Local	4.1%
331	Parovarian Cyst	4.1%
332	Pericardial Cyst	4.1%
333	Thymic Cyst	4.1%
334	Carcinogenesis	4.1%
335	Myxoid cyst	4.1%
336	Metastasis	4.1%
337	Nose Neoplasms	4.1%
338	Polyhydramnios	4.1%
339	Obstetric Labor Complications	4.1%
340	Ectopic Pregnancy	4.1%
341	Pregnancy, Prolonged	4.1%
342	Puerperal Disorders	4.1%
343	Oligohydramnios	4.1%
344	Prenatal Injuries	4.1%
345	Latent Autoimmune Diabetes in Adults	4%
346	Chorioamnionitis	4%
347	Pheochromocytoma	4%
348	Alveolar rhabdomyosarcoma	4%
349	Diabetes Mellitus, Experimental	4%
350	Primary amyloidosis	3.9%
351	granulosa cell tumor	3.9%
352	Kidney Calculi	3.9%
353	Ureteral Calculi	3.9%
354	Abruptio Placentae	3.9%
355	Placenta Accreta	3.9%
356	Lambert-Eaton Myasthenic Syndrome	3.8%
357	Uterine Cervicitis	3.8%
358	Leukorrhea	3.8%
359	Palatal Neoplasms	3.8%
360	Adenocarcinoma	3.7%
361	Carcinoma in Situ	3.7%
362	Carcinoma, Transitional Cell	3.7%
363	Phyllodes Tumor	3.7%
364	Dysgerminoma	3.7%
365	Hemangioendothelioma	3.7%
366	Lipoma	3.7%
367	Myoma	3.7%
368	Myxoma	3.7%
369	Neuroma	3.7%
370	Papilloma	3.7%
371	Pseudomyxoma Peritonei	3.7%
372	Seminoma	3.7%
373	Papillomatosis	3.7%
374	Angiolipoma	3.7%
375	Myelolipoma	3.7%
376	Neoplasms, Bone Tissue	3.7%
377	Neoplasms, Fibrous Tissue	3.7%
378	Smooth Muscle Tumor	3.7%
379	Adenomatosis, Pulmonary	3.7%
380	Adenomatous Polyps	3.7%
381	Carcinoma, Large Cell	3.7%
382	Carcinoma, Small Cell	3.7%
383	Desmoplastic Small Round Cell Tumor	3.7%
384	Chondroma	3.7%
385	Enchondroma	3.7%
386	Fetal Diseases	3.7%
387	Pregnancy Complications, Cardiovascular	3.7%
388	Pregnancy Complications, Hematologic	3.6%
389	Pregnancy Complications, Infectious	3.6%
390	Fetal Death	3.6%
391	Perinatal death	3.6%
392	Pituitary Apoplexy	3.6%
393	Morning Sickness	3.6%
394	Opsoclonus-Myoclonus Syndrome	3.5%
395	Puerperal Infection	3.4%
396	Postpartum Hemorrhage	3.4%
397	Bacterial Vaginosis	3.4%
398	Cystitis	3.3%
399	Hydronephrosis	3.3%
400	Hyperoxaluria	3.3%
401	Kidney Cortex Necrosis	3.3%
402	Kidney Papillary Necrosis	3.3%
403	Nephritis	3.3%
404	Nephrosclerosis	3.3%
405	Nephrosis	3.3%
406	Perinephritis	3.3%
407	Kidney Failure	3.3%
408	Uremia	3.3%
409	Ureteral obstruction	3.3%
410	Ureterocele	3.3%
411	Urethral Obstruction	3.3%
412	Urethritis	3.3%
413	Vesico-Ureteral Reflux	3.3%
414	Urinary Retention	3.3%
415	Oxalosis	3.3%
416	Renal Insufficiency	3.3%
417	Trichomonas Vaginitis	3.3%
418	Uterine Perforation	3.3%
419	Metrorrhagia	3.3%
420	Choledochal Cyst	3.3%
421	Renal Osteodystrophy	3.3%
422	Renal rickets	3.3%
423	Waldenstrom Macroglobulinemia	3.3%
424	Multiple Myeloma	3.3%
425	Peutz-Jeghers Syndrome	3.3%
426	Myelitis, Transverse	3.3%
427	Cushing Syndrome	3.2%
428	Hyperaldosteronism	3.2%
429	Hyperparathyroidism, Secondary	3.2%
430	Hypoaldosteronism	3.2%
431	Thyrotoxicosis	3.2%
432	Hyperparathyroidism, Primary	3.2%
433	Thyroid Hormone Resistance Syndrome	3.2%
434	Meningeal Neoplasms	3.2%
435	Diabetic Foot	3.2%
436	Leukemia, Myelomonocytic, Chronic	3.2%
437	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	3.2%
438	Nasopharyngeal carcinoma	3.2%
439	Hepatorenal Syndrome	3%
440	Bacteriuria	3%
441	Glycosuria	3%
442	Hematuria	3%
443	Renal hypertension	3%
444	Oliguria	3%
445	Polyuria	3%
446	Proteinuria	3%
447	Pyuria	3%
448	Renal Artery Obstruction	3%
449	Renal Artery Stenosis	3%
450	Urinary Calculi	3%
451	Cystocele	3%
452	Nephrocalcinosis	3%
453	Urinary Incontinence	3%
454	Menorrhagia	3%
455	Ear Neoplasms	2.9%
456	Eyelid Neoplasms	2.9%
457	Lung Neoplasms	2.9%
458	Pleural Neoplasms	2.9%
459	Mastocytosis	2.9%
460	Sturge-Weber Syndrome	2.9%
461	Brain Neoplasms	2.9%
462	Salivary Gland Neoplasms	2.9%
463	Spinal Cord Neoplasms	2.9%
464	Tongue Neoplasms	2.9%
465	Gastrointestinal Stromal Tumors	2.9%
466	Pyelocystitis	2.9%
467	Hemangioma, Cavernous	2.9%
468	Addison Disease	2.9%
469	Diabetic Angiopathies	2.9%
470	Autoimmune thyroiditis	2.9%
471	Primary Adrenal Insufficiency	2.9%
472	Leukemia, T-Cell	2.9%
473	Leukemia, B-Cell	2.9%
474	neurofibroma	2.9%
475	Lymphoma, Follicular	2.9%
476	T-Cell Lymphoma	2.9%
477	Mantle cell lymphoma	2.9%
478	Diabetic Neuropathies	2.8%
479	Myxedema	2.8%
480	Diabetic Amyotrophy	2.8%
481	Diabetic Autonomic Neuropathy	2.8%
482	Diabetic Cardiomyopathies	2.8%
483	Hyperprolactinemia	2.8%
484	Adenoid Cystic Carcinoma	2.8%
485	fibroma	2.8%
486	Fibromatosis	2.8%
487	Osteoblastoma	2.8%
488	Osteoma	2.8%
489	Rhabdomyoma	2.8%
490	Chondromatosis	2.8%
491	Adenocarcinoma, Clear Cell	2.8%
492	Cholangiocarcinoma	2.8%
493	Cervical Intraepithelial Neoplasia	2.8%
494	Hemangioblastoma	2.8%
495	Lymphoma, Extranodal NK-T-Cell	2.8%
496	Enuresis	2.7%
497	Pharyngeal Neoplasms	2.7%
498	Central Nervous System Cysts	2.6%
499	Bile Duct Neoplasms	2.6%
500	gallbladder neoplasm	2.6%
501	Intestinal Neoplasms	2.6%
502	Penile Neoplasms	2.6%
503	Prostatic Neoplasms	2.6%
504	Stomach Neoplasms	2.6%
505	Glycosuria, Renal	2.6%
506	Polycythemia Vera	2.6%
507	Gigantism	2.5%
508	Acromegaly	2.5%
509	Diabetic Ketoacidosis	2.5%
510	Pancreatic Pseudocyst	2.4%
511	Laryngeal neoplasm	2.4%
512	AIDS-Associated Nephropathy	2.4%
513	Lymphatic Metastasis	2.4%
514	Neoplasms, Unknown Primary	2.4%
515	Leukemic Infiltration	2.4%
516	Neoplasm Micrometastasis	2.4%
517	Mastocytoma	2.4%
518	Chlamydia Infections	2.4%
519	Gonorrhea	2.4%
520	Meningeal Carcinomatosis	2.4%
521	Mastocytosis, Systemic	2.4%
522	Leukemia, Myeloid, Chronic-Phase	2.4%
523	Pyelonephritis	2.4%
524	Xeroderma Pigmentosum	2.4%
525	Hyperglycemic Hyperosmolar Nonketotic Coma	2.3%
526	Hashimoto Disease	2.3%
527	Fibromatosis, Aggressive	2.3%
528	Fibromatosis, Abdominal	2.3%
529	Klatskin Tumor	2.3%
530	Syphilis	2.2%
531	Abortion, Habitual	2.2%
532	Dystocia	2.2%
533	Eclampsia	2.2%
534	Fetal Membranes, Premature Rupture	2.2%
535	Placental Insufficiency	2.2%
536	Pre-Eclampsia	2.2%
537	Prenatal Exposure Delayed Effects	2.2%
538	HELLP Syndrome	2.2%
539	Placenta, Retained	2.2%
540	Bronchial Neoplasms	2.2%
541	Multiple Pulmonary Nodules	2.2%
542	Supratentorial Neoplasms	2.1%
543	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	2.1%
544	Leukemia, Large Granular Lymphocytic	2.1%
545	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	2.1%
546	Lymphoma, T-Cell, Cutaneous	2.1%
547	Lymphoma, AIDS-Related	2.1%
548	Enteropathy-Associated T-Cell Lymphoma	2.1%
549	Primary Effusion Lymphoma	2.1%
550	Glomerulonephritis	2.1%
551	Nephritis, Interstitial	2.1%
552	Lipoid nephrosis	2.1%
553	Nephrotic Syndrome	2.1%
554	Pyelitis	2.1%
555	Pyonephrosis	2.1%
556	Urethral Stenosis	2.1%
557	Nephrogenic Diabetes Insipidus	2.1%
558	Congenital Nephrogenic Diabetes Insipidus	2.1%
559	Acute kidney injury	2.1%
560	Urethral stricture	2.1%
561	Abortion, Veterinary	2%
562	Pregnancy Complications, Parasitic	2%
563	Hypopharyngeal Neoplasms	1.9%
564	Pleural Effusion, Malignant	1.9%
565	Hypopharyngeal Cancer	1.9%
566	Parotid Neoplasms	1.9%
567	Prostatic Neoplasms, Castration-Resistant	1.9%
568	Lactation Disorder	1.9%
569	Mastitis	1.9%
570	Depression, Postpartum	1.9%
571	Embryo Loss	1.9%
572	Fetal Resorption	1.9%
573	Hyperemesis Gravidarum	1.9%
574	Azotemia	1.9%
575	Albuminuria	1.9%
576	Hemoglobinuria	1.9%
577	Hypertension, Renovascular	1.9%
578	Urge Incontinence	1.9%
579	Diabetic Retinopathy	1.8%
580	Dupuytren Contracture	1.8%
581	Urticaria Pigmentosa	1.8%
582	Brain Stem Neoplasms	1.8%
583	Mycosis Fungoides	1.8%
584	Lymphomatoid Papulosis	1.8%
585	Plasmablastic lymphoma	1.8%
586	Cecal Neoplasms	1.8%
587	Duodenal Neoplasms	1.8%
588	Burkitt Lymphoma	1.8%
589	Fetal Growth Retardation	1.7%
590	Embolism, Amniotic Fluid	1.7%
591	Fetal Hypoxia	1.7%
592	Fetal Alcohol Spectrum Disorders	1.7%
593	Breech Presentation	1.7%
594	Stillbirth	1.7%
595	Polycystic Kidney Diseases	1.7%
596	Diurnal Enuresis	1.7%
597	Renal Aminoacidurias	1.7%
598	Fanconi Syndrome	1.7%
599	Pseudohypoaldosteronism	1.7%
600	Liddle Syndrome	1.7%
601	Hemolytic-Uremic Syndrome	1.7%
602	Zellweger Syndrome	1.7%
603	Lymphogranuloma Venereum	1.7%
604	Nasopharyngeal Neoplasms	1.6%
605	Colorectal Neoplasms	1.6%
606	Tonsillar Neoplasms	1.6%
607	Cerebellar Neoplasms	1.6%
608	Choroid Plexus Papilloma	1.6%
609	Renal tubular acidosis	1.5%
610	Paranasal Sinus Neoplasms	1.5%
611	Zollinger-Ellison syndrome	1.5%
612	Balkan Nephropathy	1.5%
613	Focal glomerulosclerosis	1.5%
614	Kidney Failure, Chronic	1.5%
615	Waterhouse-Friderichsen Syndrome	1.5%
616	Sezary Syndrome	1.5%
617	Appendiceal Neoplasms	1.5%
618	Colonic Neoplasms	1.5%
619	Rectal Neoplasms	1.5%
620	Cell Transformation, Viral	1.4%
621	Meconium Aspiration Syndrome	1.4%
622	Glomerulonephritis, Membranoproliferative	1.4%
623	Hyperphosphaturia	1.3%
624	Premature Birth	1.3%
625	Maxillary Sinus Neoplasms	1.2%
626	Anti-Glomerular Basement Membrane Disease	1.2%
627	Lupus Nephritis	1.2%
628	Polycystic Kidney, Autosomal Dominant	1.2%
629	Cystinuria	1.2%
630	Atypical Hemolytic Uremic Syndrome	1.2%
631	Anus Neoplasms	1.2%
632	Sigmoid Neoplasms	1.2%
633	Galactorrhea	1.1%
634	Adrenoleukodystrophy	1%
635	Radicular Cyst	0.7%
636	Hydrops Fetalis	0.7%
637	Familial Hypophosphatemic Rickets	0.7%

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