MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Carcinoma, Large Cell

(UMLS:C0206704)

Definition:: A tumor of undifferentiated (anaplastic) cells of large size. It is usually bronchogenic. (From Dorland, 27th ed)
UMLS ID:: C0206704
MeSH ID:: D018287

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.470.200.260

Synonym(s)

Carcinoma, Large Cell

LARGE CELL CARCINOMA

Large Cell Carcinoma

Large cell carcinoma

Large cell carcinoma NOS

Large cell carcinoma, NOS

large cell carcinoma

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Adenosine Triphosphate	20156429	CTD
2	Cyclophosphamide	6301671	CTD
3	Ifosfamide	206339	CTD
4	Paclitaxel	8643967	CTD
5	Radon	22539606	CTD
6	Vinorelbine	12796036	CTD
7	gemcitabine	12796036	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Adenocarcinoma	48.4%
2	Carcinoma in Situ	48.4%
3	Carcinoma, Transitional Cell	48.4%
4	Carcinoma, Small Cell	48.4%
5	Basal cell carcinoma	47.3%
6	Carcinoma, Papillary	47.3%
7	Squamous cell carcinoma	47.3%
8	Carcinoma, Basal Cell	47.3%
9	Cystadenocarcinoma	39%
10	Mucoepidermoid Carcinoma	39%
11	Carcinoma, Ehrlich Tumor	38.9%
12	Carcinoma, Lewis Lung	38.9%
13	Adenoid Cystic Carcinoma	36%
14	Adenocarcinoma, Clear Cell	36%
15	Cholangiocarcinoma	36%
16	Cervical Intraepithelial Neoplasia	36%
17	Bowen's Disease	35.1%
18	Adenoma	34.4%
19	Cystadenoma	30.1%
20	Mesothelioma	30.1%
21	Klatskin Tumor	29.9%
22	Neoplasms, Neuroepithelial	26.8%
23	Gliomatosis cerebri	26.8%
24	Carcinoma, Lobular	25.6%
25	leukemia	25.4%
26	Neoplasms, Germ Cell and Embryonal	25.4%
27	Germ Cell Cancer	25.4%
28	Carcinoid Tumor	25.1%
29	Papilloma	22.6%
30	Pseudomyxoma Peritonei	22.6%
31	Papillomatosis	22.6%
32	Adenomatosis, Pulmonary	22.6%
33	Adenomatous Polyps	22.6%
34	Malignant Carcinoid Syndrome	20.8%
35	Choriocarcinoma	20.4%
36	Neuroectodermal Tumors	19.8%
37	Adenofibroma	18.9%
38	Fibroadenoma	18.9%
39	Acanthoma	18.5%
40	Adenoma, Acidophil	18.4%
41	Ganglioneuroma	18.4%
42	Glioma	18.4%
43	Malignant Glioma	18.4%
44	Histiocytic Disorders, Malignant	16.9%
45	Hamartoma	16.4%
46	Neoplasms, Hormone-Dependent	16.4%
47	Neoplasms, Multiple Primary	16.4%
48	Paraneoplastic Syndromes	16.4%
49	Precancerous Conditions	16.4%
50	Neoplasms, Second Primary	16.4%
51	Carcinosarcoma	16.3%
52	Hemangiosarcoma	16.3%
53	lymphangiosarcoma	16.3%
54	Medulloblastoma	16.3%
55	Carcinoid Heart Disease	15.3%
56	Ameloblastoma	14.8%
57	Angiokeratoma	14.8%
58	Chordoma	14.8%
59	Hemangioma	14.8%
60	hemangiopericytoma	14.8%
61	Lymphangioma	14.8%
62	Mesenchymoma	14.8%
63	Nevus	14.8%
64	Teratoma	14.8%
65	Hepatoblastoma	14.8%
66	Mixed Tumor, Mullerian	14.8%
67	Germinoma	14.8%
68	Teratocarcinoma	14.8%
69	Angiofibroma	14.8%
70	Sarcoma	14.8%
71	Carcinoma, Ovarian Epithelial	14.7%
72	melanoma	14.5%
73	Astrocytoma	14.3%
74	Ependymoma	14.3%
75	oligodendroglioma	14.3%
76	Ganglioglioma	14.3%
77	gliosarcoma	14.3%
78	Anaplastic astrocytoma	14.3%
79	Anaplastic Oligodendroglioma	14.3%
80	Carcinoma, Pancreatic Ductal	13.5%
81	Basal Cell Nevus Syndrome	12.9%
82	Chondrosarcoma	12.9%
83	Craniopharyngioma	12.9%
84	leiomyosarcoma	12.9%
85	liposarcoma	12.9%
86	synovial sarcoma	12.9%
87	Neuroectodermal Tumor, Melanotic	12.9%
88	Angiomyolipoma	12.9%
89	Clear Cell Sarcoma of Soft Tissue	12.9%
90	Alveolar Soft Part Sarcoma	12.9%
91	Neuroendocrine Tumors	12.9%
92	Sarcoma, Myeloid	12.9%
93	Adrenocortical carcinoma	12.8%
94	Carcinoma 256, Walker	12.8%
95	Meningioma	12.7%
96	Lymphoma	12.6%
97	Nasopharyngeal carcinoma	12.6%
98	Glioblastoma	12.3%
99	Neuroblastoma	12.3%
100	Glioblastoma Multiforme	12.3%
101	Dermoid Cyst	12.2%
102	Leukemia, Plasma Cell	12.2%
103	Trophoblastic Neoplasms	11.8%
104	Composite Lymphoma	11.8%
105	Leukemia, Experimental	11.7%
106	Ganglioneuroblastoma	11.2%
107	Fibrosarcoma	11.2%
108	Osteosarcoma	11.2%
109	Renal Cell Carcinoma	11%
110	Papillary Renal Cell Carcinoma	11%
111	Cyst	10.8%
112	Neoplastic Processes	10.8%
113	Neoplastic Syndromes, Hereditary	10.8%
114	Pregnancy Complications, Neoplastic	10.8%
115	Carcinoma, Endometrioid	10.8%
116	Neurilemmoma	10.8%
117	Hutchinson's Melanotic Freckle	10.8%
118	Melanoma, Amelanotic	10.8%
119	Neoplasms, Experimental	10.6%
120	Hepatocellular Adenoma	10.5%
121	Malignant Fibrous Histiocytoma	10.4%
122	Retinoblastoma	10.2%
123	Vipoma	10.2%
124	Melanoma, Experimental	10%
125	Gastrinoma	9.9%
126	Glucagonoma	9.9%
127	Plasmacytoma	9.9%
128	Malignant histiocytosis	9.8%
129	Leukemia L1210	9.8%
130	Leukemia P388	9.8%
131	Histiocytic sarcoma	9.8%
132	Phyllodes Tumor	9.7%
133	Dysgerminoma	9.7%
134	Hemangioendothelioma	9.7%
135	Lipoma	9.7%
136	Myoma	9.7%
137	Myxoma	9.7%
138	Neuroma	9.7%
139	Seminoma	9.7%
140	Angiolipoma	9.7%
141	Myelolipoma	9.7%
142	Neoplasms, Bone Tissue	9.7%
143	Neoplasms, Fibrous Tissue	9.7%
144	Smooth Muscle Tumor	9.7%
145	Desmoplastic Small Round Cell Tumor	9.7%
146	Chondroma	9.7%
147	Enchondroma	9.7%
148	Paraganglioma	9.6%
149	Rhabdomyosarcoma	9.6%
150	Giant Cell Tumor of Bone	9.6%
151	Leukemia, Radiation-Induced	9.5%
152	Sarcoma, Experimental	9.1%
153	Thymoma	9%
154	Dermatofibrosarcoma	8.8%
155	Dermatofibrosarcoma Protuberans	8.8%
156	Prolactinoma	8.7%
157	Growth Hormone-Secreting Pituitary Adenoma	8.7%
158	Endometrial Stromal Sarcoma	8.6%
159	Abdominal Neoplasms	8.5%
160	Erythroplasia	8.5%
161	Follicular cyst	8.5%
162	Head and Neck Neoplasms	8.5%
163	Mucocele	8.5%
164	Pilonidal Cyst	8.5%
165	Soft Tissue Neoplasms	8.5%
166	Thoracic Neoplasms	8.5%
167	Thyroglossal Cyst	8.5%
168	Synovial Cyst	8.5%
169	Aberrant Crypt Foci	8.5%
170	Sarcoma 180	8.1%
171	Pheochromocytoma	7.9%
172	Alveolar rhabdomyosarcoma	7.9%
173	Neoplasms, Radiation-Induced	7.9%
174	Lymphangioleiomyomatosis	7.7%
175	Multiple Endocrine Neoplasia	7.4%
176	Hodgkin Disease	7.3%
177	Lymphoma, Non-Hodgkin	7.3%
178	fibroma	7.2%
179	Fibromatosis	7.2%
180	Osteoblastoma	7.2%
181	Osteoma	7.2%
182	Rhabdomyoma	7.2%
183	Chondromatosis	7.2%
184	Hemangioblastoma	7.2%
185	Lymphoma, Extranodal NK-T-Cell	7.2%
186	Paraneoplastic Encephalomyelitis	6.8%
187	Neurofibrosarcoma	6.7%
188	Mammary Neoplasms, Experimental	6.7%
189	Leukemia, Myelomonocytic, Chronic	6.5%
190	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	6.5%
191	insulinoma	6.2%
192	Lymphomatoid Granulomatosis	6.2%
193	Optic Nerve Glioma	6%
194	Digestive System Neoplasms	6%
195	Endocrine Gland Neoplasms	6%
196	Eye Neoplasms	6%
197	Nervous System Neoplasms	6%
198	Fibromatosis, Aggressive	6%
199	Fibromatosis, Abdominal	6%
200	Primary amyloidosis	5.9%
201	Bone neoplasms	5.7%
202	Leukoplakia	5.7%
203	Lymphocele	5.7%
204	Pancreatic Cyst	5.7%
205	Skin Neoplasms	5.7%
206	Hematologic Neoplasms	5.7%
207	Nephroblastoma	5.6%
208	Barrett Esophagus	5.6%
209	Breast Cyst	5.6%
210	Actinic keratosis	5.6%
211	Mediastinal Cyst	5.6%
212	Neoplasm Invasiveness	5.6%
213	Neoplasm Metastasis	5.6%
214	Neoplasm Recurrence, Local	5.6%
215	Parovarian Cyst	5.6%
216	Pericardial Cyst	5.6%
217	Splenic Neoplasms	5.6%
218	Thymic Cyst	5.6%
219	Carcinogenesis	5.6%
220	Myxoid cyst	5.6%
221	Metastasis	5.6%
222	Adenomatous Polyposis Coli	5.4%
223	Hydatidiform Mole	5.2%
224	Tuberous Sclerosis	5.1%
225	Mastocytosis	5%
226	Sturge-Weber Syndrome	5%
227	Retroperitoneal Neoplasms	4.9%
228	Gastrointestinal Stromal Tumors	4.9%
229	Hemangioma, Cavernous	4.9%
230	Mastocytoma	4.9%
231	Leukemia, T-Cell	4.8%
232	Leukemia, B-Cell	4.8%
233	Mesoblastic Nephroma	4.8%
234	neurofibroma	4.8%
235	Mastocytosis, Systemic	4.8%
236	Lymphoma, Follicular	4.8%
237	T-Cell Lymphoma	4.8%
238	Mantle cell lymphoma	4.8%
239	Acoustic Neuroma	4.8%
240	Leukemia, Myeloid, Chronic-Phase	4.8%
241	Multiple Endocrine Neoplasia Type 1	4.4%
242	Waldenstrom Macroglobulinemia	4.2%
243	Multiple Myeloma	4.2%
244	Corpus Luteum Cyst	4.1%
245	Ovarian Cysts	4.1%
246	Parathyroid Neoplasms	4.1%
247	Peritoneal Neoplasms	4.1%
248	Thyroid Neoplasm	4.1%
249	Thyroid carcinoma	4.1%
250	Liver Neoplasms, Experimental	3.9%
251	granulosa cell tumor	3.7%
252	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	3.6%
253	Leukemia, Large Granular Lymphocytic	3.6%
254	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	3.6%
255	Lymphoma, T-Cell, Cutaneous	3.6%
256	Lymphoma, AIDS-Related	3.6%
257	Enteropathy-Associated T-Cell Lymphoma	3.6%
258	Primary Effusion Lymphoma	3.6%
259	Pancreatic Neoplasm	3.4%
260	Choledochal Cyst	3.4%
261	Tracheal Neoplasms	3.4%
262	Mouth Neoplasms	3.4%
263	Central Nervous System Neoplasms	3.4%
264	Vascular Neoplasms	3.4%
265	Thymus Neoplasms	3.4%
266	Genital Neoplasms, Female	3.3%
267	Pancreatic Pseudocyst	3.3%
268	Peutz-Jeghers Syndrome	3.3%
269	Leukoplakia, Oral	3.3%
270	Paraneoplastic Cerebellar Degeneration	3.3%
271	Lymphatic Metastasis	3.3%
272	Neoplasms, Unknown Primary	3.3%
273	Leukemic Infiltration	3.3%
274	Breast Neoplasms, Male	3.3%
275	Neoplasm Micrometastasis	3.3%
276	Triple Negative Breast Neoplasms	3.3%
277	Dupuytren Contracture	3.1%
278	Urticaria Pigmentosa	3%
279	Mycosis Fungoides	3%
280	Lymphomatoid Papulosis	3%
281	Plasmablastic lymphoma	3%
282	Leydig Cell Tumor	2.9%
283	Esophageal Neoplasms	2.7%
284	Limbic Encephalitis	2.7%
285	Thyroid Nodule	2.6%
286	Adrenal Gland Neoplasms	2.6%
287	Gastrointestinal Neoplasms	2.6%
288	Genital Neoplasms, Male	2.6%
289	Liver neoplasms	2.6%
290	Uveal Neoplasms	2.6%
291	Denys-Drash Syndrome	2.5%
292	Urologic Neoplasms	2.5%
293	Sebaceous Gland Neoplasms	2.5%
294	Spinal Neoplasms	2.5%
295	Bone Marrow Neoplasms	2.5%
296	Polycystic Ovary Syndrome	2.4%
297	Burkitt Lymphoma	2.4%
298	Lambert-Eaton Myasthenic Syndrome	2.4%
299	Testicular Neoplasms	2.4%
300	Meningeal Neoplasms	2.2%
301	Opsoclonus-Myoclonus Syndrome	2.1%
302	Sezary Syndrome	2%
303	Xeroderma Pigmentosum	1.9%
304	Myelitis, Transverse	1.8%
305	Ear Neoplasms	1.7%
306	Eyelid Neoplasms	1.7%
307	Lung Neoplasms	1.7%
308	Nose Neoplasms	1.7%
309	Pleural Neoplasms	1.7%
310	ovarian neoplasm	1.7%
311	Cell Transformation, Viral	1.6%
312	Brain Neoplasms	1.6%
313	Salivary Gland Neoplasms	1.6%
314	Spinal Cord Neoplasms	1.6%
315	Tongue Neoplasms	1.6%
316	Palatal Neoplasms	1.6%
317	Uterine Neoplasms	1.6%
318	Vaginal Neoplasms	1.6%
319	Vulvar Neoplasms	1.6%
320	Uterine Cancer	1.6%
321	Fallopian Tube Neoplasms	1.6%
322	Meningeal Carcinomatosis	1.6%
323	Pituitary Adenoma	1.5%
324	Pituitary Neoplasms	1.5%
325	Pharyngeal Neoplasms	1.4%
326	Central Nervous System Cysts	1.3%
327	Bile Duct Neoplasms	1.3%
328	gallbladder neoplasm	1.3%
329	Intestinal Neoplasms	1.3%
330	Penile Neoplasms	1.3%
331	Prostatic Neoplasms	1.3%
332	Stomach Neoplasms	1.3%
333	Polycythemia Vera	1.3%
334	Bronchial Neoplasms	1.2%
335	Zollinger-Ellison syndrome	1.2%
336	Multiple Pulmonary Nodules	1.2%
337	Supratentorial Neoplasms	1.2%
338	Endometrial Neoplasms	1.2%
339	Laryngeal neoplasm	1.1%
340	Bladder Neoplasm	1.1%
341	Kidney Neoplasm	1.1%
342	Ureteral Neoplasms	1.1%
343	Urethral Neoplasms	1.1%
344	Brain Stem Neoplasms	1%
345	Hypopharyngeal Neoplasms	1%
346	Pleural Effusion, Malignant	1%
347	Hypopharyngeal Cancer	1%
348	Parotid Neoplasms	1%
349	Prostatic Neoplasms, Castration-Resistant	1%
350	Nelson Syndrome	1%
351	Choroid Plexus Papilloma	0.9%
352	Cecal Neoplasms	0.8%
353	Duodenal Neoplasms	0.8%
354	Tonsillar Neoplasms	0.8%
355	Cerebellar Neoplasms	0.8%
356	Nasopharyngeal Neoplasms	0.7%
357	Colorectal Neoplasms	0.7%
358	Radicular Cyst	0.7%
359	Appendiceal Neoplasms	0.7%
360	Colonic Neoplasms	0.7%
361	Rectal Neoplasms	0.7%
362	Paranasal Sinus Neoplasms	0.6%
363	Anus Neoplasms	0.5%
364	Sigmoid Neoplasms	0.5%
365	Maxillary Sinus Neoplasms	0.5%

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