MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Ganglioneuroma

(UMLS:C0017075)

Definition:: A benign neoplasm that usually arises from the sympathetic trunk in the mediastinum. Histologic features include spindle cell proliferation (resembling a neurofibroma) and the presence of large ganglion cells. The tumor may present clinically with HORNER SYNDROME or diarrhea due to ectopic production of vasoactive intestinal peptide. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p966)
UMLS ID:: C0017075
MeSH ID:: D005729

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.465.625.600.355|C04.557.470.670.355|C04.557.580.625.600.355

Synonym(s)

Ganglioneuroma

GANGLIONEUROFIBROMA

GANGLIONEUROMA, BENIGN

Gangliocytoma

Ganglioneuroma (Schwannian Stroma-Dominant)

Neural Crest Tumor, Benign

gangliocytoma

gangliocytomas

ganglioneuroma

10.

ganglioneuromas

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Paroxetine	FAERS: 3	US FAERS
2	Risperidone	FAERS: 2	US FAERS
3	Atomoxetine Hydrochloride	FAERS: 1	US FAERS
4	Azacitidine	FAERS: 1 Canada Vigilance: 1	Canada Vigilance US FAERS
5	Dimethyl Fumarate	FAERS: 1	US FAERS
6	Methylphenidate	FAERS: 1	US FAERS
7	Etoposide		OFFSIDES
8	Ifosfamide		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Glioma	61.7%
2	Malignant Glioma	61.7%
3	Medulloblastoma	61.3%
4	Astrocytoma	46%
5	Ependymoma	46%
6	oligodendroglioma	46%
7	Ganglioglioma	46%
8	gliosarcoma	46%
9	Anaplastic astrocytoma	46%
10	Anaplastic Oligodendroglioma	46%
11	Craniopharyngioma	42.3%
12	Neuroectodermal Tumor, Melanotic	42.3%
13	Neuroendocrine Tumors	42.3%
14	Retinoblastoma	39.4%
15	Glioblastoma	38.3%
16	Neuroblastoma	38.3%
17	Glioblastoma Multiforme	38.3%
18	melanoma	36.9%
19	Adenoma, Acidophil	36.2%
20	leukemia	34.4%
21	Ganglioneuroblastoma	34.4%
22	Carcinoid Tumor	32.6%
23	Neurilemmoma	31.6%
24	Basal cell carcinoma	29.5%
25	Carcinoma, Papillary	29.5%
26	Squamous cell carcinoma	29.5%
27	Cystadenoma	29.5%
28	Mesothelioma	29.5%
29	Carcinoma, Basal Cell	29.5%
30	Adenoma	29%
31	Carcinoma	29%
32	Epithelioma	29%
33	Paraganglioma	28.7%
34	Meningioma	28.4%
35	Histiocytic Disorders, Malignant	27.6%
36	Chordoma	27.4%
37	Teratoma	27.4%
38	Germinoma	27.4%
39	Teratocarcinoma	27.4%
40	Trophoblastic Neoplasms	26.4%
41	Hutchinson's Melanotic Freckle	26.3%
42	Melanoma, Amelanotic	26.3%
43	Melanoma, Experimental	25.7%
44	Cystadenocarcinoma	25.2%
45	Mucoepidermoid Carcinoma	25.2%
46	Malignant Carcinoid Syndrome	25.2%
47	Carcinosarcoma	25.2%
48	Hemangiosarcoma	25.2%
49	lymphangiosarcoma	25.2%
50	Carcinoma, Ehrlich Tumor	24.2%
51	Carcinoma, Lewis Lung	24.2%
52	Neoplasms, Germ Cell and Embryonal	23.4%
53	Germ Cell Cancer	23.4%
54	Lymphoma	23.1%
55	Optic Nerve Glioma	22.9%
56	Dermoid Cyst	22.9%
57	Composite Lymphoma	22.2%
58	Neoplasms, Glandular and Epithelial	22.1%
59	Hamartoma	22%
60	Neoplasms, Hormone-Dependent	22%
61	Neoplasms, Multiple Primary	22%
62	Paraneoplastic Syndromes	22%
63	Precancerous Conditions	22%
64	Neoplasms, Second Primary	22%
65	Pheochromocytoma	21.9%
66	Carcinoma, Lobular	21.8%
67	Neuroectodermal Tumors	21.4%
68	Carcinoma 256, Walker	21.4%
69	Bowen's Disease	21%
70	Leukemia, Plasma Cell	21%
71	Choriocarcinoma	20.9%
72	Leukemia, Experimental	20.8%
73	Acanthoma	20%
74	Adenofibroma	19.9%
75	Fibroadenoma	19.9%
76	Ameloblastoma	19.4%
77	Angiokeratoma	19.4%
78	Hemangioma	19.4%
79	hemangiopericytoma	19.4%
80	Lymphangioma	19.4%
81	Mesenchymoma	19.4%
82	Nevus	19.4%
83	Hepatoblastoma	19.4%
84	Mixed Tumor, Mullerian	19.4%
85	Neoplasms, Neuroepithelial	19.4%
86	Angiofibroma	19.4%
87	Gliomatosis cerebri	19.4%
88	Sarcoma	19.4%
89	Chondrosarcoma	19.2%
90	leiomyosarcoma	19.2%
91	liposarcoma	19.2%
92	synovial sarcoma	19.2%
93	Angiomyolipoma	19.2%
94	Clear Cell Sarcoma of Soft Tissue	19.2%
95	Alveolar Soft Part Sarcoma	19.2%
96	Sarcoma, Myeloid	19.2%
97	Carcinoid Heart Disease	18.8%
98	Adenocarcinoma	18.4%
99	Carcinoma in Situ	18.4%
100	Carcinoma, Transitional Cell	18.4%
101	Papilloma	18.4%
102	Pseudomyxoma Peritonei	18.4%
103	Papillomatosis	18.4%
104	Adenomatosis, Pulmonary	18.4%
105	Adenomatous Polyps	18.4%
106	Carcinoma, Large Cell	18.4%
107	Carcinoma, Small Cell	18.4%
108	Leukemia, Radiation-Induced	18%
109	Cyst	17.8%
110	Neoplastic Processes	17.8%
111	Neoplastic Syndromes, Hereditary	17.8%
112	Pregnancy Complications, Neoplastic	17.8%
113	Neoplasms, Experimental	17.6%
114	Dysgerminoma	16.8%
115	Neuroma	16.8%
116	Seminoma	16.8%
117	Fibrosarcoma	16.3%
118	Osteosarcoma	16.3%
119	Sarcoma, Experimental	15.8%
120	Endometrial Stromal Sarcoma	15.7%
121	Thymoma	15.7%
122	Plasmacytoma	15.6%
123	Malignant histiocytosis	15.5%
124	Histiocytic sarcoma	15.5%
125	Multiple Endocrine Neoplasia	15.1%
126	Leukemia L1210	14.8%
127	Leukemia P388	14.8%
128	Malignant Fibrous Histiocytoma	14.8%
129	Neoplasms, Radiation-Induced	14.7%
130	Acoustic Neuroma	14.6%
131	Lymphangioleiomyomatosis	13.8%
132	Basal Cell Nevus Syndrome	13.7%
133	Rhabdomyosarcoma	13.4%
134	Giant Cell Tumor of Bone	13.4%
135	Neurofibrosarcoma	13.2%
136	Adenoid Cystic Carcinoma	13.1%
137	Adenocarcinoma, Clear Cell	13.1%
138	Cholangiocarcinoma	13.1%
139	Cervical Intraepithelial Neoplasia	13.1%
140	Hepatocellular Adenoma	13%
141	Hodgkin Disease	12.9%
142	Lymphoma, Non-Hodgkin	12.9%
143	Carcinoma, Pancreatic Ductal	12.9%
144	Ganglioneuroma	12.8%
145	Nephroblastoma	12.3%
146	Paraneoplastic Encephalomyelitis	12.2%
147	Mammary Neoplasms, Experimental	12%
148	Phyllodes Tumor	12%
149	Hemangioendothelioma	12%
150	Lipoma	12%
151	Myoma	12%
152	Myxoma	12%
153	Angiolipoma	12%
154	Myelolipoma	12%
155	Neoplasms, Bone Tissue	12%
156	Neoplasms, Fibrous Tissue	12%
157	Smooth Muscle Tumor	12%
158	Desmoplastic Small Round Cell Tumor	12%
159	Chondroma	12%
160	Enchondroma	12%
161	Vipoma	12%
162	Dermatofibrosarcoma	11.9%
163	Dermatofibrosarcoma Protuberans	11.9%
164	Sarcoma 180	11.9%
165	Tuberous Sclerosis	11.7%
166	Abdominal Neoplasms	11.5%
167	Erythroplasia	11.5%
168	Follicular cyst	11.5%
169	Head and Neck Neoplasms	11.5%
170	Mucocele	11.5%
171	Pilonidal Cyst	11.5%
172	Soft Tissue Neoplasms	11.5%
173	Thoracic Neoplasms	11.5%
174	Thyroglossal Cyst	11.5%
175	Synovial Cyst	11.5%
176	Aberrant Crypt Foci	11.5%
177	Prolactinoma	11.3%
178	Growth Hormone-Secreting Pituitary Adenoma	11.3%
179	Lymphomatoid Granulomatosis	11.3%
180	neurofibroma	11.2%
181	Primary amyloidosis	11.2%
182	Klatskin Tumor	10.5%
183	Alveolar rhabdomyosarcoma	10.5%
184	Hydatidiform Mole	10.4%
185	Carcinoma, Ovarian Epithelial	10%
186	Mesoblastic Nephroma	9.8%
187	Leukemia, Myelomonocytic, Chronic	9.6%
188	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	9.6%
189	Digestive System Neoplasms	9.6%
190	Endocrine Gland Neoplasms	9.6%
191	Eye Neoplasms	9.6%
192	Nervous System Neoplasms	9.6%
193	Bone neoplasms	9.3%
194	Leukoplakia	9.3%
195	Lymphocele	9.3%
196	Pancreatic Cyst	9.3%
197	Skin Neoplasms	9.3%
198	Hematologic Neoplasms	9.3%
199	Barrett Esophagus	9.2%
200	Breast Cyst	9.2%
201	Actinic keratosis	9.2%
202	Mediastinal Cyst	9.2%
203	Neoplasm Invasiveness	9.2%
204	Neoplasm Metastasis	9.2%
205	Neoplasm Recurrence, Local	9.2%
206	Parovarian Cyst	9.2%
207	Pericardial Cyst	9.2%
208	Splenic Neoplasms	9.2%
209	Thymic Cyst	9.2%
210	Carcinogenesis	9.2%
211	Myxoid cyst	9.2%
212	Metastasis	9.2%
213	Adenomatous Polyposis Coli	8.9%
214	Waldenstrom Macroglobulinemia	8.7%
215	Multiple Myeloma	8.7%
216	Multiple Endocrine Neoplasia Type 1	8.5%
217	fibroma	8.4%
218	Fibromatosis	8.4%
219	Osteoblastoma	8.4%
220	Osteoma	8.4%
221	Rhabdomyoma	8.4%
222	Chondromatosis	8.4%
223	Hemangioblastoma	8.4%
224	Lymphoma, Extranodal NK-T-Cell	8.4%
225	insulinoma	8.3%
226	Nasopharyngeal carcinoma	8.3%
227	Mastocytosis	8.2%
228	Sturge-Weber Syndrome	8.2%
229	Gastrointestinal Stromal Tumors	8.1%
230	Hemangioma, Cavernous	8.1%
231	Leukemia, T-Cell	8%
232	Leukemia, B-Cell	8%
233	Adrenocortical carcinoma	8%
234	Lymphoma, Follicular	8%
235	T-Cell Lymphoma	8%
236	Mantle cell lymphoma	8%
237	Liver Neoplasms, Experimental	7.8%
238	Corpus Luteum Cyst	7.6%
239	Ovarian Cysts	7.6%
240	Parathyroid Neoplasms	7.6%
241	Peritoneal Neoplasms	7.6%
242	Thyroid Neoplasm	7.6%
243	Thyroid carcinoma	7.6%
244	Gastrinoma	7.2%
245	Glucagonoma	7.2%
246	granulosa cell tumor	7.1%
247	Renal Cell Carcinoma	7.1%
248	Papillary Renal Cell Carcinoma	7.1%
249	Carcinoma, Endometrioid	6.8%
250	Mastocytoma	6.8%
251	Pancreatic Neoplasm	6.7%
252	Mastocytosis, Systemic	6.7%
253	Leukemia, Myeloid, Chronic-Phase	6.7%
254	Choledochal Cyst	6.7%
255	Fibromatosis, Aggressive	6.6%
256	Fibromatosis, Abdominal	6.6%
257	Peutz-Jeghers Syndrome	6.5%
258	Retroperitoneal Neoplasms	6.5%
259	Tracheal Neoplasms	6.2%
260	Leukoplakia, Oral	6%
261	Paraneoplastic Cerebellar Degeneration	6%
262	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	5.6%
263	Leukemia, Large Granular Lymphocytic	5.6%
264	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	5.6%
265	Lymphoma, T-Cell, Cutaneous	5.6%
266	Lymphoma, AIDS-Related	5.6%
267	Enteropathy-Associated T-Cell Lymphoma	5.6%
268	Primary Effusion Lymphoma	5.6%
269	Denys-Drash Syndrome	5.5%
270	Leydig Cell Tumor	5.3%
271	Esophageal Neoplasms	5.3%
272	Mouth Neoplasms	5.3%
273	Central Nervous System Neoplasms	5.3%
274	Vascular Neoplasms	5.3%
275	Limbic Encephalitis	5.3%
276	Thymus Neoplasms	5.3%
277	Genital Neoplasms, Female	5.2%
278	Pancreatic Pseudocyst	5.2%
279	Lymphatic Metastasis	5.2%
280	Neoplasms, Unknown Primary	5.2%
281	Leukemic Infiltration	5.2%
282	Breast Neoplasms, Male	5.2%
283	Neoplasm Micrometastasis	5.2%
284	Triple Negative Breast Neoplasms	5.2%
285	Lambert-Eaton Myasthenic Syndrome	4.8%
286	Testicular Neoplasms	4.8%
287	Thyroid Nodule	4.6%
288	Dupuytren Contracture	4.5%
289	Adrenal Gland Neoplasms	4.4%
290	Gastrointestinal Neoplasms	4.4%
291	Genital Neoplasms, Male	4.4%
292	Liver neoplasms	4.4%
293	Uveal Neoplasms	4.4%
294	Urticaria Pigmentosa	4.4%
295	Urologic Neoplasms	4.4%
296	Mycosis Fungoides	4.4%
297	Lymphomatoid Papulosis	4.4%
298	Plasmablastic lymphoma	4.4%
299	Sebaceous Gland Neoplasms	4.3%
300	Spinal Neoplasms	4.3%
301	Bone Marrow Neoplasms	4.3%
302	Polycystic Ovary Syndrome	4.3%
303	Opsoclonus-Myoclonus Syndrome	4.3%
304	Xeroderma Pigmentosum	4.2%
305	Burkitt Lymphoma	4.2%
306	Myelitis, Transverse	3.8%
307	Nose Neoplasms	3.3%
308	Sezary Syndrome	3.3%
309	ovarian neoplasm	3.3%
310	Meningeal Neoplasms	3.2%
311	Pituitary Adenoma	3.1%
312	Pituitary Neoplasms	3.1%
313	Palatal Neoplasms	3.1%
314	Ear Neoplasms	2.8%
315	Eyelid Neoplasms	2.8%
316	Lung Neoplasms	2.8%
317	Pleural Neoplasms	2.8%
318	Cell Transformation, Viral	2.7%
319	Brain Neoplasms	2.7%
320	Salivary Gland Neoplasms	2.7%
321	Spinal Cord Neoplasms	2.7%
322	Tongue Neoplasms	2.7%
323	Uterine Neoplasms	2.7%
324	Vaginal Neoplasms	2.7%
325	Vulvar Neoplasms	2.7%
326	Uterine Cancer	2.7%
327	Fallopian Tube Neoplasms	2.7%
328	Zollinger-Ellison syndrome	2.6%
329	Pharyngeal Neoplasms	2.4%
330	Central Nervous System Cysts	2.3%
331	Bile Duct Neoplasms	2.3%
332	gallbladder neoplasm	2.3%
333	Intestinal Neoplasms	2.3%
334	Penile Neoplasms	2.3%
335	Prostatic Neoplasms	2.3%
336	Stomach Neoplasms	2.3%
337	Polycythemia Vera	2.3%
338	Meningeal Carcinomatosis	2.2%
339	Laryngeal neoplasm	2.1%
340	Bladder Neoplasm	2%
341	Kidney Neoplasm	2%
342	Ureteral Neoplasms	2%
343	Urethral Neoplasms	2%
344	Bronchial Neoplasms	1.9%
345	Multiple Pulmonary Nodules	1.9%
346	Supratentorial Neoplasms	1.9%
347	Endometrial Neoplasms	1.9%
348	Hypopharyngeal Neoplasms	1.6%
349	Pleural Effusion, Malignant	1.6%
350	Hypopharyngeal Cancer	1.6%
351	Parotid Neoplasms	1.6%
352	Prostatic Neoplasms, Castration-Resistant	1.6%
353	Nelson Syndrome	1.6%
354	Brain Stem Neoplasms	1.5%
355	Cecal Neoplasms	1.4%
356	Duodenal Neoplasms	1.4%
357	Nasopharyngeal Neoplasms	1.3%
358	Tonsillar Neoplasms	1.3%
359	Choroid Plexus Papilloma	1.3%
360	Cerebellar Neoplasms	1.3%
361	Colorectal Neoplasms	1.2%
362	Paranasal Sinus Neoplasms	1.1%
363	Radicular Cyst	1.1%
364	Appendiceal Neoplasms	1.1%
365	Colonic Neoplasms	1.1%
366	Rectal Neoplasms	1.1%
367	Maxillary Sinus Neoplasms	0.9%
368	Anus Neoplasms	0.8%
369	Sigmoid Neoplasms	0.8%

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