MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Paraganglioma

(UMLS:C0030421)

Definition:: A neural crest tumor usually derived from the chromoreceptor tissue of a paraganglion, such as the carotid body, or medulla of the adrenal gland (usually called a chromaffinoma or pheochromocytoma). It is more common in women than in men. (Stedman, 25th ed; from Segen, Dictionary of Modern Medicine, 1992)
UMLS ID:: C0030421
MeSH ID:: D010235

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.465.625.650.700|C04.557.580.625.650.700

Synonym(s)

Paraganglioma

Carotid body tumors

Gangliocytic paraganglioma

Neoplasm of Paraganglion

Neoplasm of paraganglion

Neoplasm of the Paraganglion

PARAGANGLIOMAS 1

Paraganglioma NOS

Paraganglioma, NOS

10.

Paragangliomas

11.

Paraganglion Neoplasm

12.

Paraganglion Tumor

Associated Drug(s)

	Name	Reference(s)	Data Source
1	3-Iodobenzylguanidine	19927285	CTD
2	CVD protocol	12657240	CTD
3	Metoprolol	21318381	CTD
4	Phenoxybenzamine	21318381	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	melanoma	53.2%
2	Neurilemmoma	49.5%
3	Adenoma, Acidophil	49%
4	Carcinoid Tumor	47%
5	Neoplasms, Neuroepithelial	44.5%
6	Gliomatosis cerebri	44.5%
7	Craniopharyngioma	43.2%
8	Neuroectodermal Tumor, Melanotic	43.2%
9	Hutchinson's Melanotic Freckle	38.1%
10	Melanoma, Amelanotic	38.1%
11	Malignant Carcinoid Syndrome	35.1%
12	Melanoma, Experimental	31.9%
13	leukemia	29.7%
14	Neoplasms, Glandular and Epithelial	29.7%
15	Ganglioneuroma	28.7%
16	Glioma	28.7%
17	Malignant Glioma	28.7%
18	Chordoma	26.9%
19	Teratoma	26.9%
20	Germinoma	26.9%
21	Teratocarcinoma	26.9%
22	Medulloblastoma	26.1%
23	Carcinoid Heart Disease	24.8%
24	Meningioma	22.6%
25	Trophoblastic Neoplasms	22.5%
26	Histiocytic Disorders, Malignant	22.3%
27	Astrocytoma	20.9%
28	Ependymoma	20.9%
29	oligodendroglioma	20.9%
30	Ganglioglioma	20.9%
31	gliosarcoma	20.9%
32	Anaplastic astrocytoma	20.9%
33	Anaplastic Oligodendroglioma	20.9%
34	Dermoid Cyst	19.7%
35	Hamartoma	19.5%
36	Neoplasms, Hormone-Dependent	19.5%
37	Neoplasms, Multiple Primary	19.5%
38	Paraneoplastic Syndromes	19.5%
39	Precancerous Conditions	19.5%
40	Neoplasms, Second Primary	19.5%
41	Carcinosarcoma	19.4%
42	Hemangiosarcoma	19.4%
43	lymphangiosarcoma	19.4%
44	Acoustic Neuroma	18.7%
45	Lymphoma	17.9%
46	Retinoblastoma	17.4%
47	Glioblastoma	17%
48	Neuroblastoma	17%
49	Glioblastoma Multiforme	17%
50	Composite Lymphoma	16.2%
51	Adenoma	16.1%
52	Ameloblastoma	16.1%
53	Angiokeratoma	16.1%
54	Carcinoma	16.1%
55	Hemangioma	16.1%
56	hemangiopericytoma	16.1%
57	Lymphangioma	16.1%
58	Mesenchymoma	16.1%
59	Nevus	16.1%
60	Hepatoblastoma	16.1%
61	Mixed Tumor, Mullerian	16.1%
62	Angiofibroma	16.1%
63	Sarcoma	16.1%
64	Epithelioma	16.1%
65	Dysgerminoma	16%
66	Neuroma	16%
67	Seminoma	16%
68	Leukemia, Experimental	15.8%
69	Carcinoma 256, Walker	15.6%
70	Leukemia, Plasma Cell	15.5%
71	Ganglioneuroblastoma	15.1%
72	Neoplasms, Germ Cell and Embryonal	14.8%
73	Germ Cell Cancer	14.8%
74	Cyst	14.8%
75	Neoplastic Processes	14.8%
76	Neoplastic Syndromes, Hereditary	14.8%
77	Pregnancy Complications, Neoplastic	14.8%
78	Carcinoma, Ehrlich Tumor	14.8%
79	Carcinoma, Lewis Lung	14.8%
80	Neoplasms, Experimental	14.5%
81	Basal cell carcinoma	14.4%
82	Carcinoma, Papillary	14.4%
83	Squamous cell carcinoma	14.4%
84	Chondrosarcoma	14.4%
85	Cystadenoma	14.4%
86	leiomyosarcoma	14.4%
87	liposarcoma	14.4%
88	Mesothelioma	14.4%
89	synovial sarcoma	14.4%
90	Angiomyolipoma	14.4%
91	Clear Cell Sarcoma of Soft Tissue	14.4%
92	Alveolar Soft Part Sarcoma	14.4%
93	Sarcoma, Myeloid	14.4%
94	Carcinoma, Basal Cell	14.4%
95	Choriocarcinoma	13.9%
96	Leukemia, Radiation-Induced	13.3%
97	Plasmacytoma	12.2%
98	Neuroectodermal Tumors	12.2%
99	Malignant histiocytosis	12.1%
100	Histiocytic sarcoma	12.1%
101	Vipoma	12%
102	Cystadenocarcinoma	12%
103	Fibrosarcoma	12%
104	Osteosarcoma	12%
105	Mucoepidermoid Carcinoma	12%
106	Sarcoma, Experimental	11.8%
107	Thymoma	11.7%
108	Neoplasms, Radiation-Induced	11.6%
109	Leukemia L1210	11.3%
110	Leukemia P388	11.3%
111	Acanthoma	11.3%
112	Endometrial Stromal Sarcoma	11.2%
113	Multiple Endocrine Neoplasia	11.1%
114	Adenofibroma	10.7%
115	Fibroadenoma	10.7%
116	Malignant Fibrous Histiocytoma	10.7%
117	Carcinoma, Lobular	10.7%
118	Abdominal Neoplasms	9.9%
119	Erythroplasia	9.9%
120	Follicular cyst	9.9%
121	Head and Neck Neoplasms	9.9%
122	Mucocele	9.9%
123	Pilonidal Cyst	9.9%
124	Soft Tissue Neoplasms	9.9%
125	Thoracic Neoplasms	9.9%
126	Thyroglossal Cyst	9.9%
127	Synovial Cyst	9.9%
128	Aberrant Crypt Foci	9.9%
129	Optic Nerve Glioma	9.7%
130	Hodgkin Disease	9.7%
131	Lymphoma, Non-Hodgkin	9.7%
132	Lymphangioleiomyomatosis	9.6%
133	neurofibroma	9.6%
134	Adenocarcinoma	9.6%
135	Carcinoma in Situ	9.6%
136	Carcinoma, Transitional Cell	9.6%
137	Phyllodes Tumor	9.6%
138	Hemangioendothelioma	9.6%
139	Lipoma	9.6%
140	Myoma	9.6%
141	Myxoma	9.6%
142	Papilloma	9.6%
143	Pseudomyxoma Peritonei	9.6%
144	Papillomatosis	9.6%
145	Angiolipoma	9.6%
146	Myelolipoma	9.6%
147	Neoplasms, Bone Tissue	9.6%
148	Neoplasms, Fibrous Tissue	9.6%
149	Smooth Muscle Tumor	9.6%
150	Adenomatosis, Pulmonary	9.6%
151	Adenomatous Polyps	9.6%
152	Carcinoma, Large Cell	9.6%
153	Carcinoma, Small Cell	9.6%
154	Desmoplastic Small Round Cell Tumor	9.6%
155	Chondroma	9.6%
156	Enchondroma	9.6%
157	Bowen's Disease	9.5%
158	Rhabdomyosarcoma	9.5%
159	Giant Cell Tumor of Bone	9.5%
160	Paraneoplastic Encephalomyelitis	9.4%
161	Neurofibrosarcoma	9.3%
162	Mammary Neoplasms, Experimental	9.2%
163	Sarcoma 180	8.8%
164	Nephroblastoma	8.5%
165	Dermatofibrosarcoma	8.3%
166	Dermatofibrosarcoma Protuberans	8.3%
167	Hydatidiform Mole	8.3%
168	Tuberous Sclerosis	8.2%
169	Primary amyloidosis	8.2%
170	Lymphomatoid Granulomatosis	8.1%
171	Digestive System Neoplasms	7.8%
172	Endocrine Gland Neoplasms	7.8%
173	Eye Neoplasms	7.8%
174	Nervous System Neoplasms	7.8%
175	Bone neoplasms	7.6%
176	Leukoplakia	7.6%
177	Lymphocele	7.6%
178	Pancreatic Cyst	7.6%
179	Skin Neoplasms	7.6%
180	Hematologic Neoplasms	7.6%
181	Barrett Esophagus	7.4%
182	Breast Cyst	7.4%
183	Actinic keratosis	7.4%
184	Mediastinal Cyst	7.4%
185	Neoplasm Invasiveness	7.4%
186	Neoplasm Metastasis	7.4%
187	Neoplasm Recurrence, Local	7.4%
188	Parovarian Cyst	7.4%
189	Pericardial Cyst	7.4%
190	Splenic Neoplasms	7.4%
191	Thymic Cyst	7.4%
192	Carcinogenesis	7.4%
193	Myxoid cyst	7.4%
194	Metastasis	7.4%
195	Leukemia, Myelomonocytic, Chronic	7.2%
196	Neuroendocrine Tumors	7.2%
197	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	7.2%
198	Alveolar rhabdomyosarcoma	7.1%
199	Basal Cell Nevus Syndrome	6.8%
200	Mesoblastic Nephroma	6.8%
201	Hepatocellular Adenoma	6.5%
202	Adenoid Cystic Carcinoma	6.3%
203	fibroma	6.3%
204	Fibromatosis	6.3%
205	Osteoblastoma	6.3%
206	Osteoma	6.3%
207	Rhabdomyoma	6.3%
208	Chondromatosis	6.3%
209	Adenocarcinoma, Clear Cell	6.3%
210	Cholangiocarcinoma	6.3%
211	Cervical Intraepithelial Neoplasia	6.3%
212	Hemangioblastoma	6.3%
213	Lymphoma, Extranodal NK-T-Cell	6.3%
214	Waldenstrom Macroglobulinemia	6.1%
215	Multiple Myeloma	6.1%
216	Multiple Endocrine Neoplasia Type 1	6%
217	Carcinoma, Pancreatic Ductal	5.9%
218	Mastocytosis	5.9%
219	Sturge-Weber Syndrome	5.9%
220	Corpus Luteum Cyst	5.9%
221	Ovarian Cysts	5.9%
222	Gastrointestinal Stromal Tumors	5.8%
223	Hemangioma, Cavernous	5.8%
224	Leukemia, T-Cell	5.8%
225	Leukemia, B-Cell	5.8%
226	Lymphoma, Follicular	5.7%
227	T-Cell Lymphoma	5.7%
228	Mantle cell lymphoma	5.7%
229	Liver Neoplasms, Experimental	5.6%
230	Parathyroid Neoplasms	5.6%
231	Peritoneal Neoplasms	5.6%
232	Thyroid Neoplasm	5.6%
233	Thyroid carcinoma	5.6%
234	Prolactinoma	5.5%
235	Growth Hormone-Secreting Pituitary Adenoma	5.5%
236	Retroperitoneal Neoplasms	5.4%
237	Choledochal Cyst	5%
238	Peutz-Jeghers Syndrome	4.9%
239	Adenomatous Polyposis Coli	4.8%
240	Pancreatic Neoplasm	4.8%
241	Mastocytoma	4.8%
242	granulosa cell tumor	4.8%
243	Carcinoma, Ovarian Epithelial	4.8%
244	Mastocytosis, Systemic	4.8%
245	Leukemia, Myeloid, Chronic-Phase	4.8%
246	Paraganglioma	4.8%
247	Fibromatosis, Aggressive	4.7%
248	Fibromatosis, Abdominal	4.7%
249	Klatskin Tumor	4.7%
250	Tracheal Neoplasms	4.4%
251	Leukoplakia, Oral	4.3%
252	Paraneoplastic Cerebellar Degeneration	4.3%
253	Mouth Neoplasms	4.1%
254	Central Nervous System Neoplasms	4.1%
255	Vascular Neoplasms	4.1%
256	Thymus Neoplasms	4.1%
257	Genital Neoplasms, Female	4.1%
258	Pancreatic Pseudocyst	4.1%
259	Lymphatic Metastasis	4%
260	Neoplasms, Unknown Primary	4%
261	Leukemic Infiltration	4%
262	Breast Neoplasms, Male	4%
263	Neoplasm Micrometastasis	4%
264	Triple Negative Breast Neoplasms	4%
265	insulinoma	4%
266	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	3.8%
267	Leukemia, Large Granular Lymphocytic	3.8%
268	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	3.8%
269	Lymphoma, T-Cell, Cutaneous	3.8%
270	Lymphoma, AIDS-Related	3.8%
271	Enteropathy-Associated T-Cell Lymphoma	3.8%
272	Primary Effusion Lymphoma	3.8%
273	Nasopharyngeal carcinoma	3.7%
274	Esophageal Neoplasms	3.7%
275	Limbic Encephalitis	3.7%
276	Adrenocortical carcinoma	3.7%
277	Pheochromocytoma	3.6%
278	Denys-Drash Syndrome	3.5%
279	Gastrinoma	3.4%
280	Glucagonoma	3.4%
281	Adrenal Gland Neoplasms	3.4%
282	Gastrointestinal Neoplasms	3.4%
283	Genital Neoplasms, Male	3.4%
284	Liver neoplasms	3.4%
285	Uveal Neoplasms	3.4%
286	Leydig Cell Tumor	3.4%
287	Urologic Neoplasms	3.3%
288	Lambert-Eaton Myasthenic Syndrome	3.3%
289	Testicular Neoplasms	3.3%
290	Sebaceous Gland Neoplasms	3.3%
291	Spinal Neoplasms	3.3%
292	Bone Marrow Neoplasms	3.3%
293	Thyroid Nodule	3.2%
294	Polycystic Ovary Syndrome	3.2%
295	Renal Cell Carcinoma	3.2%
296	Papillary Renal Cell Carcinoma	3.2%
297	Xeroderma Pigmentosum	3%
298	Carcinoma, Endometrioid	3%
299	Dupuytren Contracture	2.9%
300	Opsoclonus-Myoclonus Syndrome	2.9%
301	Urticaria Pigmentosa	2.9%
302	Mycosis Fungoides	2.8%
303	Lymphomatoid Papulosis	2.8%
304	Plasmablastic lymphoma	2.8%
305	Burkitt Lymphoma	2.7%
306	Myelitis, Transverse	2.6%
307	Meningeal Neoplasms	2.4%
308	ovarian neoplasm	2.3%
309	Nose Neoplasms	2.2%
310	Sezary Syndrome	2.1%
311	Pituitary Adenoma	2%
312	Pituitary Neoplasms	2%
313	Palatal Neoplasms	2%
314	Ear Neoplasms	2%
315	Eyelid Neoplasms	2%
316	Lung Neoplasms	2%
317	Pleural Neoplasms	2%
318	Cell Transformation, Viral	2%
319	Brain Neoplasms	1.9%
320	Salivary Gland Neoplasms	1.9%
321	Spinal Cord Neoplasms	1.9%
322	Tongue Neoplasms	1.9%
323	Uterine Neoplasms	1.9%
324	Vaginal Neoplasms	1.9%
325	Vulvar Neoplasms	1.9%
326	Uterine Cancer	1.9%
327	Fallopian Tube Neoplasms	1.9%
328	Zollinger-Ellison syndrome	1.8%
329	Pharyngeal Neoplasms	1.7%
330	Central Nervous System Cysts	1.6%
331	Bile Duct Neoplasms	1.6%
332	gallbladder neoplasm	1.6%
333	Intestinal Neoplasms	1.6%
334	Penile Neoplasms	1.6%
335	Prostatic Neoplasms	1.6%
336	Stomach Neoplasms	1.6%
337	Polycythemia Vera	1.6%
338	Meningeal Carcinomatosis	1.6%
339	Laryngeal neoplasm	1.5%
340	Bladder Neoplasm	1.4%
341	Kidney Neoplasm	1.4%
342	Ureteral Neoplasms	1.4%
343	Urethral Neoplasms	1.4%
344	Bronchial Neoplasms	1.3%
345	Multiple Pulmonary Nodules	1.3%
346	Supratentorial Neoplasms	1.3%
347	Endometrial Neoplasms	1.3%
348	Hypopharyngeal Neoplasms	1.1%
349	Pleural Effusion, Malignant	1.1%
350	Hypopharyngeal Cancer	1.1%
351	Parotid Neoplasms	1.1%
352	Prostatic Neoplasms, Castration-Resistant	1.1%
353	Nelson Syndrome	1.1%
354	Brain Stem Neoplasms	1%
355	Cecal Neoplasms	0.9%
356	Duodenal Neoplasms	0.9%
357	Nasopharyngeal Neoplasms	0.8%
358	Colorectal Neoplasms	0.8%
359	Tonsillar Neoplasms	0.8%
360	Cerebellar Neoplasms	0.8%
361	Choroid Plexus Papilloma	0.8%
362	Paranasal Sinus Neoplasms	0.7%
363	Radicular Cyst	0.7%
364	Appendiceal Neoplasms	0.7%
365	Colonic Neoplasms	0.7%
366	Rectal Neoplasms	0.7%
367	Maxillary Sinus Neoplasms	0.5%
368	Anus Neoplasms	0.5%
369	Sigmoid Neoplasms	0.5%

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