MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Lead Poisoning, Nervous System, Adult

(UMLS:C0751863)

Definition:: Neurologic conditions in adults associated with acute or chronic exposure to lead or any of its salts. The most common lead related neurologic syndrome in adults consists of a polyneuropathy involving motor fibers. This tends to affect distal nerves and may present as wrist drop due to RADIAL NEUROPATHY. Additional features of chronic lead exposure include ANEMIA; CONSTIPATION; colicky abdominal pain; a bluish lead line of the gums; interstitial nephritis (NEPHRITIS, INTERSTITIAL); and saturnine gout. An encephalopathy may rarely occur. (From Adams et al., Principles of Neurology, 6th ed, p1212)
UMLS ID:: C0751863
MeSH ID:: D020265

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.720.475.400.350

Classification 2:

Name:

Chemically-Induced Disorders
MeSH Tree Number(s):: C25.723.522.750.500.400

Synonym(s)

Lead Poisoning, Nervous System, Adult

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Tetraethyl Lead		15521604	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Lead Poisoning, Nervous System, Childhood	48.8%
2	Manganese Poisoning	31.4%
3	Arsenic Poisoning	28.6%
4	Mercury Poisoning, Nervous System	25.5%
5	Cadmium poisoning	18.9%
6	Mercury Poisoning	18.9%
7	Neuroleptic Malignant Syndrome	16.2%
8	Alcohol-Induced Disorders, Nervous System	15.8%
9	Acrodynia	15.5%
10	Fluoride Poisoning	14.9%
11	Food Poisoning	14.9%
12	Gas Poisoning	14.9%
13	Mycotoxicosis	14.9%
14	Plant Poisoning	14.9%
15	Organophosphate poisoning	14.9%
16	Argyria	14.3%
17	Akathisia, Drug-Induced	14.3%
18	Botulism	14%
19	MPTP Poisoning	13.7%
20	Dyskinesia, Drug-Induced	13.3%
21	Chemical and Drug Induced Liver Injury	12.3%
22	Mushroom Poisoning	12.2%
23	Bites and Stings	11.8%
24	Neurotoxicity Syndromes	11.8%
25	Water Intoxication	11.2%
26	Cranial nerve diseases	10.4%
27	Demyelinating Diseases	10.4%
28	Demyelination	10.4%
29	Neuromuscular Diseases	10.4%
30	Chronobiology Disorders	10.4%
31	Psychoses, Substance-Induced	10.2%
32	Drug toxicity	9.8%
33	Motor Neuron Disease	8.4%
34	Trauma, Nervous System	8.1%
35	Alcohol Withdrawal Seizures	8.1%
36	Carbon Monoxide Poisoning	8.1%
37	Ciguatera Poisoning	8.1%
38	Ergotism	8.1%
39	Shellfish Poisoning	8.1%
40	Nervous System Neoplasms	7.9%
41	Neurologic Manifestations	7.9%
42	Drug abuse	7.7%
43	Substance Dependence	7.7%
44	Substance-Related Disorders	7.7%
45	Drug Dependence	7.7%
46	Stiff-Person Syndrome	7.3%
47	Multiple System Atrophy	7.2%
48	Ocular Motility Disorders	7%
49	Cyclophoria	7%
50	Alcohol Withdrawal Delirium	6.9%
51	Restless Legs Syndrome	6.7%
52	Polyradiculoneuropathy	6.7%
53	Polyradiculoneuritis	6.7%
54	Encephalomyelitis	6.6%
55	Prion Diseases	6.6%
56	Autonomic Dysreflexia	6.6%
57	Complex Regional Pain Syndromes	6.6%
58	Chemical and Drug Induced Liver Injury, Chronic	6.6%
59	Sleep Wake Disorders	6.4%
60	Insect Bites and Stings	6.2%
61	Subacute Combined Degeneration	6.2%
62	Salmonella food poisoning	6%
63	Spinal Muscular Atrophy	5.9%
64	Progressive Muscular Atrophy	5.9%
65	Marchiafava-Bignami Disease	5.8%
66	Amyotrophic Lateral Sclerosis	5.6%
67	Ophthalmoplegic Migraine	5.6%
68	Parkinson Disease	5.6%
69	Spinal Cord Injuries	5.5%
70	Brain Diseases	5.5%
71	Dysautonomia	5.5%
72	Meningitis	5.5%
73	Movement Disorders	5.5%
74	Pachymeningitis	5.5%
75	Spinal Cord Diseases	5.5%
76	Vagus Nerve Disorder	5.5%
77	Glossopharyngeal Neuralgia	5.5%
78	Abducens Nerve Diseases	5.5%
79	Neuromuscular Junction Diseases	5.5%
80	Tauopathies	5.5%
81	Trochlear Nerve Diseases	5.5%
82	Peripheral Nervous System Diseases	5.5%
83	Meningoencephalitis	5.4%
84	Peripheral Nerve Injuries	5.4%
85	Myasthenia Gravis	5.3%
86	Asterixis	5.3%
87	Ballismus	5.3%
88	Anticholinergic Syndrome	5%
89	Serotonin Syndrome	5%
90	Propofol Infusion Syndrome	5%
91	Dandy-Walker Syndrome	4.9%
92	Lewy Body Disease	4.9%
93	Pneumocephalus	4.9%
94	Poliomyelitis	4.9%
95	Myelitis	4.9%
96	Progressive bulbar palsy	4.9%
97	Bulbar palsy	4.9%
98	Guillain-Barre Syndrome	4.9%
99	Psychoses, Alcoholic	4.9%
100	Chronic Fatigue Syndrome	4.6%
101	Myelinolysis, Central Pontine	4.6%
102	Sleep Disorders, Circadian Rhythm	4.6%
103	Striatonigral Degeneration	4.6%
104	Lambert-Eaton Myasthenic Syndrome	4.6%
105	Causalgia	4.5%
106	Central Nervous System Cysts	4.4%
107	Central Nervous System Infection	4.4%
108	Myopathy	4.4%
109	Optic Neuropathy	4.4%
110	Epidural Abscess	4.3%
111	Olfactory Nerve Injuries	4.3%
112	Progressive supranuclear palsy	4.3%
113	Myelitis, Transverse	4.2%
114	Facial Nerve Diseases	4.2%
115	Craniocerebral Trauma	4.2%
116	Parasomnia	4.2%
117	Dyssomnias	4.2%
118	Vestibulocochlear Nerve Diseases	4.1%
119	Decerebrate State	4.1%
120	Hemiparesis	4.1%
121	Hydranencephaly	4.1%
122	Meningism	4.1%
123	Neural Tube Defects	4.1%
124	Paresis	4.1%
125	Seizures	4.1%
126	Sensation Disorders	4.1%
127	Tethered Cord Syndrome	4.1%
128	Central Nervous System Neoplasms	4.1%
129	Complex partial seizures	4.1%
130	Iniencephaly	4.1%
131	Craniorachischisis	4.1%
132	Exencephaly	4.1%
133	Monoparesis	4.1%
134	Septo-Optic Dysplasia	4.1%
135	Cortical Dysplasia	4.1%
136	Neurogenic Inflammation	4.1%
137	Gait Disorders, Neurologic	4.1%
138	Neuromuscular Manifestations	4.1%
139	Malformations of Cortical Development	4.1%
140	Sweating, Gustatory	4.1%
141	Auriculotemporal Syndrome	4.1%
142	Leukoencephalitis, Acute Hemorrhagic	4.1%
143	Encephalomyelitis, Acute Disseminated	4.1%
144	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	4.1%
145	Reflex Sympathetic Dystrophy	4%
146	Subdural Effusion	4%
147	Parkinsonian Disorders	4%
148	Nocturnal Myoclonus Syndrome	4%
149	Opsoclonus-Myoclonus Syndrome	4%
150	Miller Fisher Syndrome	4%
151	Shy-Drager Syndrome	3.9%
152	Brain Injuries	3.9%
153	Brain Neoplasms	3.9%
154	Multiple Sclerosis	3.9%
155	Spinal Cord Neoplasms	3.9%
156	Neuromyelitis Optica	3.9%
157	Horner Syndrome	3.8%
158	Marijuana Abuse	3.8%
159	Opioid-Related Disorders	3.8%
160	Nicotine Dependence	3.8%
161	Opioid abuse	3.8%
162	Phencyclidine Abuse	3.8%
163	Substance Abuse, Intravenous	3.8%
164	Substance Withdrawal Syndrome	3.8%
165	Tobacco Use Disorder	3.8%
166	Alcohol-Related Disorders	3.8%
167	Amphetamine-Related Disorders	3.8%
168	Cocaine-Related Disorders	3.8%
169	Metabolic Side Effects of Drugs and Substances	3.8%
170	Dystonia Musculorum Deformans	3.8%
171	Injection Site Reaction	3.7%
172	Infusion site reaction	3.7%
173	Facial Nerve Injuries	3.7%
174	Drug Overdose	3.7%
175	Pupil Disorders	3.5%
176	Neurobehavioral Manifestations	3.5%
177	Leukoencephalopathy, Progressive Multifocal	3.4%
178	Paraneoplastic Encephalomyelitis	3.4%
179	Uveomeningoencephalitic Syndrome	3.3%
180	Vasculitis, Central Nervous System	3.3%
181	Brain Abscess	3.3%
182	Ophthalmoplegia	3.3%
183	External Ophthalmoplegia	3.3%
184	Scrapie	3.3%
185	Sturge-Weber Syndrome	3.3%
186	Vertigo	3.3%
187	Central Cord Syndrome	3.3%
188	Jet Lag Syndrome	3.3%
189	Presenile dementia	3.3%
190	Senile dementia	3.3%
191	Meningitis, Bacterial	3.3%
192	Meningitis, Fungal	3.3%
193	Limbic Encephalitis	3.2%
194	Myasthenia Gravis, Autoimmune, Experimental	3.2%
195	Akinetic Mutism	3.2%
196	Anoxic Encephalopathy	3.2%
197	Arachnoiditis	3.2%
198	Basal Ganglia Diseases	3.2%
199	Brain Damage, Chronic	3.2%
200	Cerebellar Diseases	3.2%
201	Encephalitis	3.2%
202	Encephalomalacia	3.2%
203	Epilepsy	3.2%
204	Hydrocephalus	3.2%
205	Congenital Hydrocephalus	3.2%
206	Hypothalamic Diseases	3.2%
207	Aseptic Meningitis	3.2%
208	Neuritis	3.2%
209	Polyneuritis	3.2%
210	Radiculitis	3.2%
211	Syringomyelia	3.2%
212	Thalamic Diseases	3.2%
213	Intracranial Hypertension	3.2%
214	Polyneuropathy	3.2%
215	Mononeuritis	3.2%
216	Aura	3.2%
217	Leukoencephalopathy	3.2%
218	Essential Tremor	3.2%
219	Neuroaxonal Dystrophies	3.2%
220	Familial Tremor	3.2%
221	Headache Disorders	3.2%
222	Mononeuropathies	3.2%
223	Intracranial Hypotension	3.2%
224	Brachial Plexus Neuropathies	3.2%
225	Radiculopathy	3.2%
226	Mononeuropathy Multiplex	3.2%
227	Nerve Root Compression	3.2%
228	Brain Edema	3.2%
229	Brain Hypoxia	3.2%
230	Aqueductal Stenosis	3.2%
231	Pneumorrhachis	3.2%
232	Writer's Cramp	3.2%
233	Chorea	3.2%
234	Epilepsy, Post-Traumatic	3.2%
235	Meige Syndrome	3.2%
236	Brachial Plexus Neuritis	3.2%
237	Neuralgic Amyotrophy	3.2%
238	Cerebral Ventriculitis	3.2%
239	Tick Paralysis	3.2%
240	Huntington Disease	3.1%
241	Neonatal Abstinence Syndrome	3.1%
242	Tuberous Sclerosis	3.1%
243	Charcot-Marie-Tooth Disease	3%
244	Vocal Cord Paralysis	2.9%
245	Lupus Vasculitis, Central Nervous System	2.9%
246	Voice Disorders	2.8%
247	Voice Disturbance	2.8%
248	Canavan Disease	2.8%
249	Alexander Disease	2.8%
250	Lafora Disease	2.8%
251	Unverricht-Lundborg Syndrome	2.8%
252	Tarsal Tunnel Syndrome	2.8%
253	Cauda Equina Syndrome	2.8%
254	Posterior Leukoencephalopathy Syndrome	2.8%
255	Posterior reversible encephalopathy syndrome	2.8%
256	Ataxia Telangiectasia	2.8%
257	Smith-Magenis syndrome	2.8%
258	Brain Death	2.8%
259	Coma, Post-Head Injury	2.8%
260	Dural Arteriovenous Fistula	2.8%
261	Amblyopia	2.7%
262	Myotonia Congenita	2.7%
263	Paraneoplastic Cerebellar Degeneration	2.7%
264	Alcohol-Induced Disorders	2.7%
265	Cerebrospinal Fluid Otorrhea	2.7%
266	Cerebrospinal Fluid Rhinorrhea	2.7%
267	Neuritis, Autoimmune, Experimental	2.7%
268	Gait Ataxia	2.7%
269	Cerebellar Neoplasms	2.7%
270	Creutzfeldt-Jakob disease	2.6%
271	Basal Ganglia Cerebrovascular Disease	2.6%
272	Dementia, Vascular	2.6%
273	Brain Hemorrhage, Traumatic	2.6%
274	Brain Injuries, Diffuse	2.6%
275	Traumatic Brain Injury	2.6%
276	Cerebellar Ataxia	2.6%
277	Supratentorial Neoplasms	2.6%
278	Torticollis	2.6%
279	Multiple Sclerosis, Chronic Progressive	2.6%
280	Multiple Sclerosis, Relapsing-Remitting	2.6%
281	Cardiotoxicity	2.5%
282	Friedreich Ataxia	2.5%
283	Brain Diseases, Metabolic	2.5%
284	Cerebrovascular Disorders	2.5%
285	Myositis	2.5%
286	Optic Atrophy	2.5%
287	Optic Neuritis	2.5%
288	Papilledema	2.5%
289	Strabismus	2.5%
290	Tolosa-Hunt Syndrome	2.5%
291	Cerebrovascular Insufficiency	2.5%
292	Isaacs syndrome	2.5%
293	Dementia	2.5%
294	Myotonic Disorders	2.5%
295	Central Nervous System Fungal Infections	2.5%
296	Conus Medullaris Syndrome	2.5%
297	Myasthenic Syndromes, Congenital	2.5%
298	Spinal Cord Vascular Diseases	2.5%
299	Diabetic Neuropathies	2.4%
300	Facial Injuries	2.4%
301	Facial Neuralgia	2.4%
302	Diabetic Amyotrophy	2.4%
303	Diabetic Autonomic Neuropathy	2.4%
304	Sleep Talking	2.4%
305	Sleep Disorders, Intrinsic	2.4%
306	Orthostatic intolerance	2.4%
307	Anosmia	2.4%
308	Ataxia	2.4%
309	Athetosis	2.4%
310	Catalepsy	2.4%
311	Dystonia	2.4%
312	Hemiplegia	2.4%
313	Locked-In Syndrome	2.4%
314	Meningeal Neoplasms	2.4%
315	Meningomyelocele	2.4%
316	Muscle Hypertonia	2.4%
317	Muscle hypotonia	2.4%
318	Myoclonus	2.4%
319	Myotonia	2.4%
320	Neuralgia	2.4%
321	Paraplegia	2.4%
322	Pseudobulbar Palsy	2.4%
323	Quadriplegia	2.4%
324	Spasm	2.4%
325	Spastic Paraplegia	2.4%
326	Status Epilepticus	2.4%
327	Taste Disorders	2.4%
328	Tremor	2.4%
329	Spina Bifida	2.4%
330	Monoplegia	2.4%
331	Hypokinesia	2.4%
332	Paraparesis	2.4%
333	Bradykinesia	2.4%
334	Waxy flexibility	2.4%
335	Action Tremor	2.4%
336	Resting Tremor	2.4%
337	Dysosmia	2.4%
338	Quadriparesis	2.4%
339	Olfaction Disorders	2.4%
340	Myokymia	2.4%
341	Vestibular Neuronitis	2.4%
342	Somatosensory Disorders	2.4%
343	Neuropathic pain	2.4%
344	Hyperkinesia	2.4%
345	Intention tremor	2.4%
346	Carotid Artery Injuries	2.4%
347	Myoclonic Epilepsy	2.4%
348	Epilepsy, Temporal Lobe	2.4%
349	Epilepsy, Rolandic	2.4%
350	Benign Rolandic Epilepsy	2.4%
351	Hepatolenticular Degeneration	2.4%
352	Myotonic Dystrophy	2.4%
353	Reflex, Abnormal	2.3%
354	Hyporeflexia	2.3%
355	Hyperreflexia	2.3%
356	Akathisia	2.3%
357	Restlessness	2.3%
358	Psychomotor Agitation	2.3%
359	Tuberculosis, Meningeal	2.3%
360	Carpal Tunnel Syndrome	2.3%
361	Vascular Headaches	2.3%
362	neurofibroma	2.2%
363	Hypoxia-Ischemia, Brain	2.2%
364	Sciatica	2.2%
365	Tardive Dyskinesia	2.2%
366	Persistent Vegetative State	2.2%
367	Leukomalacia, Periventricular	2.2%
368	Cerebral Palsy	2.1%
369	Epilepsies, Partial	2.1%
370	Epilepsy, Generalized	2.1%
371	Pseudotumor Cerebri	2.1%
372	Sciatic Neuropathy	2.1%
373	Hypertensive Encephalopathy	2.1%
374	Ulnar Neuropathies	2.1%
375	Lesion of Sciatic Nerve	2.1%
376	Simple Partial Seizures	2.1%
377	Epilepsy, Reflex	2.1%
378	Ulnar Neuritis	2.1%
379	Radial nerve compression	2.1%
380	Radial Tunnel Syndrome	2.1%
381	Peroneal Neuropathies	2.1%
382	Radial Neuropathy	2.1%
383	Median Neuropathy	2.1%
384	Sciatic Nerve Palsy	2.1%
385	Femoral Neuropathy	2.1%
386	Tibial Neuropathy	2.1%
387	Ulnar Nerve Palsy	2.1%
388	Postural Orthostatic Tachycardia Syndrome	2.1%
389	Radial nerve palsy	2.1%
390	Headache Disorders, Primary	2.1%
391	Headache Disorders, Secondary	2.1%
392	Medication overuse headache	2.1%
393	Alice in Wonderland Syndrome	2.1%
394	Wernicke Encephalopathy	2.1%
395	Vertebral Artery Dissection	2.1%
396	Amnesia, Transient Global	2.1%
397	Hand-Arm Vibration Syndrome	2.1%
398	Gait Apraxia	2.1%
399	Alcohol Use Disorder	2%
400	Alcoholic Intoxication	2%
401	Heroin Dependence	2%
402	Morphine Dependence	2%
403	Alcohol abuse	2%
404	Vision Disorders	2%
405	Metamorphopsia	2%
406	Visual Impairment	2%
407	Fibromyalgia	2%
408	Optic Neuropathy, Ischemic	2%
409	Anterior Ischemic Optic Neuropathy	2%
410	Central Nervous System Bacterial Infections	2%
411	Medial Tibial Stress Syndrome	2%
412	Brain Concussion	2%
413	Optic Nerve Glioma	2%
414	Facial Hemiatrophy	2%
415	Melkersson-Rosenthal Syndrome	2%
416	Mitochondrial Myopathies	2%
417	Juvenile Myoclonic Epilepsy	2%
418	Myoclonic Epilepsies, Progressive	2%
419	Refsum Disease	2%
420	Anisocoria	2%
421	Confusion	2%
422	Facial paralysis	2%
423	Lethargy	2%
424	Memory Disorders	2%
425	Muscle Cramp	2%
426	Perceptual Disorders	2%
427	Psychomotor Disorders	2%
428	Tonic Pupil	2%
429	Eosinophilia-Myalgia Syndrome	2%
430	Anhedonia	2%
431	Disorientation	2%
432	Facial Paresis	2%
433	Memory Loss	2%
434	Hemisensory Neglect	2%
435	Dysacusis	2%
436	Toxoplasmosis, Cerebral	2%
437	Sleep Bruxism	2%
438	Anencephaly	2%
439	Meningocele	2%
440	Muscular Atrophy	2%
441	Respiratory Paralysis	2%
442	Encephalocele	2%
443	Tetany	1.9%
444	Alstrom Syndrome	1.9%
445	Cubital Tunnel Syndrome	1.9%
446	Diffuse Axonal Injury	1.9%
447	Brain Stem Neoplasms	1.9%
448	Meningitis, Cryptococcal	1.9%
449	Meningitis, Listeria	1.9%
450	Meningitis, Haemophilus	1.9%
451	Meningitis, Pneumococcal	1.9%
452	Frontotemporal dementia	1.9%
453	Mitochondrial Encephalomyopathies	1.9%
454	Amyloid Neuropathies, Familial	1.8%
455	Pituitary Adenoma	1.8%
456	Pituitary Neoplasms	1.8%
457	Acoustic Neuroma	1.8%
458	Pituitary Diseases	1.7%
459	Basal Ganglia Hemorrhage	1.7%
460	Duane Retraction Syndrome	1.7%
461	Consciousness Disorders	1.7%
462	Mental Retardation	1.7%
463	Muscle Weakness	1.7%
464	Depressed Level of Consciousness	1.7%
465	Mental deficiency	1.7%
466	Intellectual Disability	1.7%
467	Mobius Syndrome	1.7%
468	Bell Palsy	1.7%
469	Catatonia	1.7%
470	Herpes Zoster Oticus	1.6%
471	Thoracic Outlet Syndrome	1.6%
472	Familial Periodic Paralysis	1.6%
473	Drug Eruptions	1.6%
474	Aphonia	1.6%
475	Sleep Deprivation	1.6%
476	Dysphonia	1.6%
477	Binge Drinking	1.6%
478	Pituitary Apoplexy	1.6%
479	Auditory Perceptual Disorders	1.6%
480	Carotid Artery Diseases	1.6%
481	Brain Ischemia	1.6%
482	Esotropia	1.6%
483	Exotropia	1.6%
484	Hypotension, Orthostatic	1.6%
485	Sleep Apnea Syndromes	1.6%
486	Cerebrovascular accident	1.6%
487	Polymyositis	1.6%
488	Kluver-Bucy Syndrome	1.6%
489	Vasospasm, Intracranial	1.6%
490	Spinal Cord Ischemia	1.6%
491	Intracranial Arterial Diseases	1.6%
492	Post-Exercise Hypotension	1.6%
493	Giant Cell Arteritis	1.6%
494	Temporal Arteritis	1.6%
495	Disorders of Excessive Somnolence	1.6%
496	Sleep Initiation and Maintenance Disorders	1.6%
497	Night Terrors	1.6%
498	Somnambulism	1.6%
499	Trigeminal Nerve Disorder	1.6%
500	Transient Insomnia	1.6%
501	Sleep Paralysis	1.6%
502	Chronic Insomnia	1.6%
503	REM Sleep Behavior Disorder	1.6%
504	Hypersomnia	1.6%
505	Brain Contusion	1.6%
506	Dermal Sinus	1.6%
507	Dysgeusia	1.6%
508	Formication	1.6%
509	Hyperalgesia	1.6%
510	Hyperesthesia	1.6%
511	Hypesthesia	1.6%
512	Language Disorders	1.6%
513	Numbness	1.6%
514	Paresthesia	1.6%
515	Paraparesis, Spastic	1.6%
516	Spina Bifida Cystica	1.6%
517	Trismus	1.6%
518	Spina Bifida Occulta	1.6%
519	Epilepsia Partialis Continua	1.6%
520	Hypogeusia	1.6%
521	Meningeal Carcinomatosis	1.6%
522	Brown-Sequard Syndrome	1.6%
523	Lissencephaly	1.6%
524	Polymicrogyria	1.6%
525	Pachygyria	1.6%
526	Schizencephaly	1.6%
527	Lockjaw	1.6%
528	Allodynia	1.6%
529	Brain Infarction	1.6%
530	Periventricular Nodular Heterotopia	1.6%
531	Ageusia	1.6%
532	Tuberculosis, Central Nervous System	1.6%
533	Classical Lissencephalies and Subcortical Band Heterotopias	1.6%
534	Polyradiculopathy	1.6%
535	Post-Traumatic Headache	1.6%
536	Tension Headache	1.6%
537	Epilepsy, Complex Partial	1.6%
538	Migraine Disorders	1.6%
539	Abdominal Migraine	1.6%
540	Status Migrainosus	1.6%
541	Cervicogenic Headache	1.6%
542	Subarachnoid Hemorrhage, Traumatic	1.6%
543	Carotid Artery, Internal, Dissection	1.6%
544	Choroid Plexus Papilloma	1.6%
545	Adrenoleukodystrophy	1.6%
546	Subacute Sclerosing Panencephalitis	1.5%
547	Putaminal Hemorrhage	1.4%
548	Myalgia	1.4%
549	Neuronal Ceroid-Lipofuscinoses	1.4%
550	Infarction, Middle Cerebral Artery	1.4%
551	Infarction, Anterior Cerebral Artery	1.4%
552	Infarction, Posterior Cerebral Artery	1.4%
553	Alexia	1.4%
554	Dyslexia	1.4%
555	Eye Injuries	1.3%
556	Cluster Headache	1.3%
557	Migraine with Aura	1.3%
558	Familial Hemiplegic Migraine	1.3%
559	Chronic Paroxysmal Hemicrania	1.3%
560	SUNCT Syndrome	1.3%
561	Paroxysmal Hemicrania	1.3%
562	Cerebral Infarction	1.3%
563	Brain Stem Infarctions	1.3%
564	Muscular Dystrophy	1.3%
565	Congenital nystagmus	1.3%
566	Orbital Myositis	1.3%
567	MELAS Syndrome	1.3%
568	Diplopia	1.3%
569	Muscle Rigidity	1.3%
570	Muscle Spasticity	1.3%
571	Scotoma	1.3%
572	Photophobia	1.3%
573	Cogwheel Rigidity	1.3%
574	Hemifacial Spasm	1.3%
575	Amaurosis	1.3%
576	Blindness	1.3%
577	Nuchal Rigidity	1.3%
578	Reye Syndrome	1.3%
579	Neuroaspergillosis	1.3%
580	Pyomyositis	1.3%
581	Hematoma, Subdural	1.3%
582	Hematoma, Epidural, Cranial	1.3%
583	Intracranial Embolism and Thrombosis	1.3%
584	Hepatic Encephalopathy	1.3%
585	Agnosia	1.3%
586	Apraxias	1.3%
587	Hallucinations	1.3%
588	Hemianopsia	1.3%
589	Hyperacusis	1.3%
590	Tinnitus	1.3%
591	Visual Agnosia	1.3%
592	Anosognosia	1.3%
593	Wernicke-Korsakoff Syndrome	1.3%
594	Phonophobia	1.3%
595	Hearing Loss	1.3%
596	Sarcopenia	1.3%
597	Moyamoya Disease	1.3%
598	Optic Atrophy, Hereditary, Leber	1.3%
599	Aicardi's syndrome	1.3%
600	Neurofibrosarcoma	1.2%
601	Hoarseness	1.2%
602	Cockayne Syndrome	1.2%
603	Empty Sella Syndrome	1.2%
604	Hyperpituitarism	1.2%
605	Hypopituitarism	1.2%
606	Hypophysitis	1.2%
607	Cardiomyopathy, Alcoholic	1.2%
608	Pancreatitis, Alcoholic	1.2%
609	Kearns-Sayre syndrome	1.2%
610	Cerebral Arterial Diseases	1.2%
611	Vertebrobasilar Insufficiency	1.2%
612	Anterior Spinal Artery Syndrome	1.2%
613	Basilar Artery Stenosis	1.2%
614	Vertebral Artery Stenosis	1.2%
615	Sleep Apnea, Obstructive	1.2%
616	Sleep Apnea, Central	1.2%
617	Intracranial Hemorrhage, Hypertensive	1.2%
618	Transient Cerebral Ischemia	1.2%
619	Narcolepsy	1.2%
620	Trigeminal Neuralgia	1.2%
621	Kleine-Levin Syndrome	1.2%
622	Agraphia	1.2%
623	Anomia	1.2%
624	Cluttering	1.2%
625	Language Development Disorders	1.2%
626	Speech Disorders	1.2%
627	Syncope	1.2%
628	Stupor	1.2%
629	Dysgraphia	1.2%
630	Presyncope	1.2%
631	Dyslalia	1.2%
632	Lateral Medullary Syndrome	1.2%
633	Asthma, Aspirin-Induced	1.2%
634	West Nile Fever	1.2%
635	Pseudorabies	1.1%
636	Amnesia	1.1%
637	Delirium	1.1%
638	Holoprosencephaly	1.1%
639	Dissociative Amnesia	1.1%
640	Color blindness	1.1%
641	Global Amnesia	1.1%
642	Cri-du-Chat Syndrome	1.1%
643	Down Syndrome	1.1%
644	Brain Diseases, Metabolic, Inborn	1.1%
645	Trisomy 21	1.1%
646	POEMS Syndrome	1.1%
647	Meningioma	1.1%
648	Williams Syndrome	1.1%
649	Microcephaly	1.1%
650	Macrocephaly	1.1%
651	Neurosyphilis	1.1%
652	Hypokalemic periodic paralysis	1.1%
653	Porencephaly	1.1%
654	Hematoma, Subdural, Intracranial	1%
655	Hematoma, Subdural, Chronic	1%
656	Hematoma, Subdural, Acute	1%
657	Hyperprolactinemia	1%
658	Subclavian Steal Syndrome	1%
659	Pick Disease of the Brain	1%
660	Cataplexy	1%
661	Aphasia	1%
662	Articulation Disorders	1%
663	Echolalia	1%
664	Stuttering	1%
665	Dysphasia	1%
666	Fetal Alcohol Spectrum Disorders	1%
667	Toxoplasmosis, Congenital	1%
668	Eye Burns	1%
669	Malaria, Cerebral	1%
670	Carotid Stenosis	1%
671	Intracranial Aneurysm	1%
672	Welander Distal Myopathy	1%
673	Neurocysticercosis	1%
674	Acute Generalized Exanthematous Pustulosis	1%
675	Amaurosis Fugax	1%
676	Blindness, Cortical	1%
677	Dyscalculia	1%
678	Intracranial Arteriosclerosis	1%
679	Cerebral Atherosclerosis	1%
680	Rett Syndrome	1%
681	Subarachnoid Hemorrhage	1%
682	Cerebral Arteriosclerosis	1%
683	Cerebral Hemorrhage	1%
684	Cerebral Thrombosis	1%
685	Intracranial Embolism	1%
686	Intracranial Thrombosis	1%
687	Deafness	1%
688	Hearing Loss, Sudden	1%
689	Gerstmann Syndrome	1%
690	Hearing Loss, Bilateral	1%
691	Hearing Loss, High-Frequency	1%
692	Hearing Loss, Mixed Conductive-Sensorineural	1%
693	Prosopagnosia	1%
694	Apraxia, Ideomotor	1%
695	Charles Bonnet Syndrome	1%
696	Hearing Loss, Unilateral	1%
697	Complete Hearing Loss	1%
698	Alien Hand Syndrome	1%
699	Deaf Mutism	1%
700	Prader-Willi Syndrome	0.9%
701	AIDS Dementia Complex	0.9%
702	Phantom pain	0.9%
703	Phantom Limb Pain	0.9%
704	Lyme Neuroborreliosis	0.9%
705	Dysarthria	0.9%
706	Dermatomyositis	0.8%
707	Kernicterus	0.8%
708	Corneal Scar	0.8%
709	Mutism	0.8%
710	Selective Mutism	0.8%
711	Muscular Dystrophy, Duchenne	0.8%
712	Acromegaly	0.8%
713	Erythema Nodosum	0.8%
714	Serum Sickness	0.8%
715	Menkes Kinky Hair Syndrome	0.8%
716	Waterhouse-Friderichsen Syndrome	0.8%
717	Retrograde amnesia	0.8%
718	Amnesia, Anterograde	0.8%
719	Carotid Artery Thrombosis	0.8%
720	Cerebral Amyloid Angiopathy	0.8%
721	Sinus Thrombosis, Intracranial	0.8%
722	Rubinstein-Taybi Syndrome	0.7%
723	Alexia, Pure	0.7%
724	Cavernous Sinus Thrombosis	0.7%
725	Sagittal Sinus Thrombosis	0.7%
726	Fragile X Syndrome	0.7%
727	Corneal Perforation	0.7%
728	Fatty Liver, Alcoholic	0.6%
729	Hepatitis, Alcoholic	0.6%
730	Liver Cirrhosis, Alcoholic	0.6%
731	Toxic Epidermal Necrolysis	0.6%
732	Stevens-Johnson Syndrome	0.6%
733	Galactosemias	0.6%
734	Urea Cycle Disorders, Inborn	0.6%
735	Tyrosinemias	0.6%
736	Nelson Syndrome	0.6%
737	Fabry Disease	0.6%
738	Prolactinoma	0.6%
739	Growth Hormone-Secreting Pituitary Adenoma	0.6%
740	Homocystinuria	0.5%
741	Leigh Disease	0.5%
742	Mucopolysaccharidosis II	0.5%
743	Carbamoyl-Phosphate Synthase I Deficiency Disease	0.4%
744	Zellweger Syndrome	0.4%
745	Glycogen storage disease type II	0.4%
746	Gaucher Disease	0.3%
747	Tay-Sachs Disease	0.3%
748	Niemann-Pick Disease, Type C	0.3%

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