MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Neuroendocrine Tumors

(UMLS:C0206754)

Definition:: Tumors whose cells possess secretory granules and originate from the neuroectoderm, i.e., the cells of the ectoblast or epiblast that program the neuroendocrine system. Common properties across most neuroendocrine tumors include ectopic hormone production (often via APUD CELLS), the presence of tumor-associated antigens, and isozyme composition.
UMLS ID:: C0206754
MeSH ID:: D018358

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.465.625.650|C04.557.580.625.650

Synonym(s)

Neuroendocrine Tumors

Neuroendocrine Neoplasm

Neuroendocrine Tumor

Neuroendocrine neoplasia

Neuroendocrine neoplasm

Neuroendocrine tumor

Neuroendocrine tumors

Neuroendocrine tumour

neoplasms neuroendocrine

10.

neuroendocrine neoplasm

11.

neuroendocrine tumor

12.

neuroendocrine tumors

13.

neuroendocrine tumour

14.

neuroendocrine tumours

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Carboplatin	11468447	CTD
2	Everolimus	21306238	CTD
3	FDE protocol	12056713	CTD
4	Octreotide	1322274 9803143 18463367	CTD
5	Paclitaxel	11468447	CTD
6	Sunitinib	26581635	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Neoplasms, Neuroepithelial	58.4%
2	Gliomatosis cerebri	58.4%
3	Craniopharyngioma	58.1%
4	Neuroectodermal Tumor, Melanotic	58.1%
5	Medulloblastoma	42.9%
6	Ganglioneuroma	42.3%
7	Glioma	42.3%
8	Malignant Glioma	42.3%
9	Astrocytoma	34.4%
10	Ependymoma	34.4%
11	oligodendroglioma	34.4%
12	Ganglioglioma	34.4%
13	gliosarcoma	34.4%
14	Anaplastic astrocytoma	34.4%
15	Anaplastic Oligodendroglioma	34.4%
16	leukemia	33.3%
17	Neoplasms, Glandular and Epithelial	33.3%
18	Chordoma	32.6%
19	Teratoma	32.6%
20	Germinoma	32.6%
21	Teratocarcinoma	32.6%
22	Glioblastoma	30.5%
23	Neuroblastoma	30.5%
24	Glioblastoma Multiforme	30.5%
25	Ganglioneuroblastoma	28.5%
26	Meningioma	27.6%
27	Trophoblastic Neoplasms	26.7%
28	Retinoblastoma	25.5%
29	Histiocytic Disorders, Malignant	25%
30	Dermoid Cyst	24.8%
31	Carcinosarcoma	24.4%
32	Hemangiosarcoma	24.4%
33	lymphangiosarcoma	24.4%
34	Dysgerminoma	21.5%
35	Neuroma	21.5%
36	Seminoma	21.5%
37	Hamartoma	20.9%
38	Neoplasms, Hormone-Dependent	20.9%
39	Neoplasms, Multiple Primary	20.9%
40	Paraneoplastic Syndromes	20.9%
41	Precancerous Conditions	20.9%
42	Neoplasms, Second Primary	20.9%
43	Carcinoma 256, Walker	20.3%
44	Lymphoma	20%
45	Adenoma	19.6%
46	Ameloblastoma	19.6%
47	Angiokeratoma	19.6%
48	Carcinoma	19.6%
49	Hemangioma	19.6%
50	hemangiopericytoma	19.6%
51	Lymphangioma	19.6%
52	Mesenchymoma	19.6%
53	Nevus	19.6%
54	Hepatoblastoma	19.6%
55	Mixed Tumor, Mullerian	19.6%
56	Angiofibroma	19.6%
57	Composite Lymphoma	19.6%
58	Sarcoma	19.6%
59	Epithelioma	19.6%
60	Leukemia, Plasma Cell	19.5%
61	Basal cell carcinoma	19.4%
62	Carcinoma, Papillary	19.4%
63	Squamous cell carcinoma	19.4%
64	Chondrosarcoma	19.4%
65	Cystadenoma	19.4%
66	leiomyosarcoma	19.4%
67	liposarcoma	19.4%
68	Mesothelioma	19.4%
69	synovial sarcoma	19.4%
70	Angiomyolipoma	19.4%
71	Clear Cell Sarcoma of Soft Tissue	19.4%
72	Alveolar Soft Part Sarcoma	19.4%
73	Sarcoma, Myeloid	19.4%
74	Carcinoma, Basal Cell	19.4%
75	Choriocarcinoma	18.9%
76	Leukemia, Experimental	18.5%
77	Carcinoma, Ehrlich Tumor	18.2%
78	Carcinoma, Lewis Lung	18.2%
79	melanoma	17.4%
80	Cystadenocarcinoma	16.9%
81	Fibrosarcoma	16.9%
82	Osteosarcoma	16.9%
83	Mucoepidermoid Carcinoma	16.9%
84	Neoplasms, Germ Cell and Embryonal	16.7%
85	Germ Cell Cancer	16.7%
86	Optic Nerve Glioma	15.9%
87	Cyst	15.8%
88	Neoplastic Processes	15.8%
89	Neoplastic Syndromes, Hereditary	15.8%
90	Pregnancy Complications, Neoplastic	15.8%
91	Leukemia, Radiation-Induced	15.6%
92	Adenofibroma	15.6%
93	Fibroadenoma	15.6%
94	Malignant Fibrous Histiocytoma	15.6%
95	Neoplasms, Experimental	15.5%
96	Neurilemmoma	15.3%
97	Plasmacytoma	14.8%
98	Neuroectodermal Tumors	14.8%
99	Malignant histiocytosis	14.6%
100	Leukemia L1210	14.6%
101	Leukemia P388	14.6%
102	Histiocytic sarcoma	14.6%
103	Acanthoma	14.6%
104	Carcinoma, Lobular	14.6%
105	Sarcoma, Experimental	14.5%
106	Endometrial Stromal Sarcoma	14.4%
107	Bowen's Disease	14.4%
108	Rhabdomyosarcoma	14.4%
109	Giant Cell Tumor of Bone	14.4%
110	Thymoma	14.4%
111	Neurofibrosarcoma	14.3%
112	Melanoma, Experimental	13.7%
113	Adenoma, Acidophil	13.5%
114	Dermatofibrosarcoma	13.2%
115	Dermatofibrosarcoma Protuberans	13.2%
116	Adenocarcinoma	12.9%
117	Carcinoma in Situ	12.9%
118	Carcinoma, Transitional Cell	12.9%
119	Phyllodes Tumor	12.9%
120	Hemangioendothelioma	12.9%
121	Lipoma	12.9%
122	Myoma	12.9%
123	Myxoma	12.9%
124	Papilloma	12.9%
125	Pseudomyxoma Peritonei	12.9%
126	Papillomatosis	12.9%
127	Angiolipoma	12.9%
128	Myelolipoma	12.9%
129	Neoplasms, Bone Tissue	12.9%
130	Neoplasms, Fibrous Tissue	12.9%
131	Smooth Muscle Tumor	12.9%
132	Adenomatosis, Pulmonary	12.9%
133	Adenomatous Polyps	12.9%
134	Carcinoma, Large Cell	12.9%
135	Carcinoma, Small Cell	12.9%
136	Desmoplastic Small Round Cell Tumor	12.9%
137	Lymphangioleiomyomatosis	12.9%
138	Chondroma	12.9%
139	Enchondroma	12.9%
140	neurofibroma	12.9%
141	Multiple Endocrine Neoplasia	12.6%
142	Hutchinson's Melanotic Freckle	12.5%
143	Melanoma, Amelanotic	12.5%
144	Neoplasms, Radiation-Induced	12.4%
145	Hydatidiform Mole	12.2%
146	Sarcoma 180	12.1%
147	Alveolar rhabdomyosarcoma	12%
148	Hodgkin Disease	11.7%
149	Lymphoma, Non-Hodgkin	11.7%
150	Carcinoid Tumor	11.5%
151	Abdominal Neoplasms	11.1%
152	Erythroplasia	11.1%
153	Follicular cyst	11.1%
154	Head and Neck Neoplasms	11.1%
155	Mucocele	11.1%
156	Pilonidal Cyst	11.1%
157	Soft Tissue Neoplasms	11.1%
158	Thoracic Neoplasms	11.1%
159	Thyroglossal Cyst	11.1%
160	Synovial Cyst	11.1%
161	Aberrant Crypt Foci	11.1%
162	Paraneoplastic Encephalomyelitis	10.8%
163	Mammary Neoplasms, Experimental	10.6%
164	Lymphomatoid Granulomatosis	10.3%
165	Nephroblastoma	10.1%
166	Primary amyloidosis	9.8%
167	Leukemia, Myelomonocytic, Chronic	9.7%
168	Neuroendocrine Tumors	9.7%
169	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	9.7%
170	Adenoid Cystic Carcinoma	9.6%
171	fibroma	9.6%
172	Fibromatosis	9.6%
173	Osteoblastoma	9.6%
174	Osteoma	9.6%
175	Rhabdomyoma	9.6%
176	Chondromatosis	9.6%
177	Adenocarcinoma, Clear Cell	9.6%
178	Cholangiocarcinoma	9.6%
179	Cervical Intraepithelial Neoplasia	9.6%
180	Hemangioblastoma	9.6%
181	Lymphoma, Extranodal NK-T-Cell	9.6%
182	Malignant Carcinoid Syndrome	9.5%
183	Basal Cell Nevus Syndrome	9.2%
184	Tuberous Sclerosis	9.2%
185	Carcinoma, Pancreatic Ductal	8.8%
186	Digestive System Neoplasms	8.8%
187	Endocrine Gland Neoplasms	8.8%
188	Eye Neoplasms	8.8%
189	Nervous System Neoplasms	8.8%
190	Hepatocellular Adenoma	8.7%
191	Bone neoplasms	8.5%
192	Leukoplakia	8.5%
193	Lymphocele	8.5%
194	Pancreatic Cyst	8.5%
195	Skin Neoplasms	8.5%
196	Hematologic Neoplasms	8.5%
197	Mesoblastic Nephroma	8.5%
198	Barrett Esophagus	8.3%
199	Breast Cyst	8.3%
200	Actinic keratosis	8.3%
201	Mediastinal Cyst	8.3%
202	Neoplasm Invasiveness	8.3%
203	Neoplasm Metastasis	8.3%
204	Neoplasm Recurrence, Local	8.3%
205	Parovarian Cyst	8.3%
206	Pericardial Cyst	8.3%
207	Splenic Neoplasms	8.3%
208	Thymic Cyst	8.3%
209	Carcinogenesis	8.3%
210	Myxoid cyst	8.3%
211	Metastasis	8.3%
212	Fibromatosis, Aggressive	8%
213	Fibromatosis, Abdominal	8%
214	Klatskin Tumor	8%
215	Acoustic Neuroma	8%
216	Mastocytosis	7.9%
217	Sturge-Weber Syndrome	7.9%
218	Gastrointestinal Stromal Tumors	7.8%
219	Hemangioma, Cavernous	7.8%
220	Leukemia, T-Cell	7.7%
221	Leukemia, B-Cell	7.7%
222	Lymphoma, Follicular	7.7%
223	T-Cell Lymphoma	7.7%
224	Mantle cell lymphoma	7.7%
225	Multiple Endocrine Neoplasia Type 1	7.5%
226	Prolactinoma	7.4%
227	Growth Hormone-Secreting Pituitary Adenoma	7.4%
228	Waldenstrom Macroglobulinemia	7.4%
229	Multiple Myeloma	7.4%
230	Mastocytoma	7.3%
231	Carcinoid Heart Disease	7.3%
232	Mastocytosis, Systemic	7.2%
233	Leukemia, Myeloid, Chronic-Phase	7.2%
234	Paraganglioma	7.2%
235	Parathyroid Neoplasms	6.7%
236	Peritoneal Neoplasms	6.7%
237	Thyroid Neoplasm	6.7%
238	Thyroid carcinoma	6.7%
239	Liver Neoplasms, Experimental	6.6%
240	Corpus Luteum Cyst	6.6%
241	Ovarian Cysts	6.6%
242	Retroperitoneal Neoplasms	6.5%
243	granulosa cell tumor	6.4%
244	Carcinoma, Ovarian Epithelial	6.4%
245	Adenomatous Polyposis Coli	6.3%
246	Vipoma	6.1%
247	insulinoma	6%
248	Pheochromocytoma	6%
249	Pancreatic Neoplasm	5.8%
250	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	5.8%
251	Leukemia, Large Granular Lymphocytic	5.8%
252	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	5.8%
253	Lymphoma, T-Cell, Cutaneous	5.7%
254	Lymphoma, AIDS-Related	5.7%
255	Enteropathy-Associated T-Cell Lymphoma	5.7%
256	Primary Effusion Lymphoma	5.7%
257	Choledochal Cyst	5.6%
258	Tracheal Neoplasms	5.6%
259	Adrenocortical carcinoma	5.5%
260	Peutz-Jeghers Syndrome	5.5%
261	Leukoplakia, Oral	5.5%
262	Paraneoplastic Cerebellar Degeneration	5.4%
263	Gastrinoma	5.4%
264	Glucagonoma	5.4%
265	Nasopharyngeal carcinoma	5.2%
266	Leydig Cell Tumor	5.1%
267	Mouth Neoplasms	5%
268	Central Nervous System Neoplasms	5%
269	Vascular Neoplasms	5%
270	Thymus Neoplasms	5%
271	Dupuytren Contracture	4.9%
272	Genital Neoplasms, Female	4.9%
273	Pancreatic Pseudocyst	4.9%
274	Lymphatic Metastasis	4.9%
275	Neoplasms, Unknown Primary	4.9%
276	Leukemic Infiltration	4.9%
277	Breast Neoplasms, Male	4.9%
278	Neoplasm Micrometastasis	4.9%
279	Triple Negative Breast Neoplasms	4.9%
280	Urticaria Pigmentosa	4.8%
281	Renal Cell Carcinoma	4.8%
282	Papillary Renal Cell Carcinoma	4.8%
283	Mycosis Fungoides	4.8%
284	Lymphomatoid Papulosis	4.8%
285	Plasmablastic lymphoma	4.8%
286	Esophageal Neoplasms	4.7%
287	Denys-Drash Syndrome	4.7%
288	Limbic Encephalitis	4.7%
289	Carcinoma, Endometrioid	4.6%
290	Thyroid Nodule	4.3%
291	Lambert-Eaton Myasthenic Syndrome	4.1%
292	Testicular Neoplasms	4.1%
293	Burkitt Lymphoma	4.1%
294	Adrenal Gland Neoplasms	4.1%
295	Gastrointestinal Neoplasms	4.1%
296	Genital Neoplasms, Male	4.1%
297	Liver neoplasms	4.1%
298	Uveal Neoplasms	4.1%
299	Urologic Neoplasms	4%
300	Sebaceous Gland Neoplasms	3.9%
301	Spinal Neoplasms	3.9%
302	Bone Marrow Neoplasms	3.9%
303	Polycystic Ovary Syndrome	3.9%
304	Opsoclonus-Myoclonus Syndrome	3.7%
305	Sezary Syndrome	3.4%
306	Xeroderma Pigmentosum	3.3%
307	Myelitis, Transverse	3.3%
308	Meningeal Neoplasms	3.3%
309	Nose Neoplasms	3%
310	Palatal Neoplasms	2.8%
311	ovarian neoplasm	2.8%
312	Pituitary Adenoma	2.7%
313	Pituitary Neoplasms	2.7%
314	Ear Neoplasms	2.7%
315	Eyelid Neoplasms	2.7%
316	Lung Neoplasms	2.7%
317	Pleural Neoplasms	2.7%
318	Cell Transformation, Viral	2.6%
319	Brain Neoplasms	2.6%
320	Salivary Gland Neoplasms	2.6%
321	Spinal Cord Neoplasms	2.6%
322	Tongue Neoplasms	2.6%
323	Uterine Neoplasms	2.6%
324	Vaginal Neoplasms	2.6%
325	Vulvar Neoplasms	2.6%
326	Uterine Cancer	2.6%
327	Fallopian Tube Neoplasms	2.6%
328	Meningeal Carcinomatosis	2.4%
329	Pharyngeal Neoplasms	2.3%
330	Central Nervous System Cysts	2.2%
331	Bile Duct Neoplasms	2.2%
332	gallbladder neoplasm	2.2%
333	Intestinal Neoplasms	2.2%
334	Penile Neoplasms	2.2%
335	Prostatic Neoplasms	2.2%
336	Stomach Neoplasms	2.2%
337	Zollinger-Ellison syndrome	2.2%
338	Polycythemia Vera	2.2%
339	Bronchial Neoplasms	2%
340	Multiple Pulmonary Nodules	2%
341	Laryngeal neoplasm	2%
342	Supratentorial Neoplasms	1.9%
343	Endometrial Neoplasms	1.9%
344	Bladder Neoplasm	1.9%
345	Kidney Neoplasm	1.9%
346	Ureteral Neoplasms	1.9%
347	Urethral Neoplasms	1.9%
348	Hypopharyngeal Neoplasms	1.6%
349	Pleural Effusion, Malignant	1.6%
350	Hypopharyngeal Cancer	1.6%
351	Parotid Neoplasms	1.6%
352	Prostatic Neoplasms, Castration-Resistant	1.6%
353	Nelson Syndrome	1.6%
354	Brain Stem Neoplasms	1.6%
355	Choroid Plexus Papilloma	1.4%
356	Cecal Neoplasms	1.4%
357	Duodenal Neoplasms	1.4%
358	Tonsillar Neoplasms	1.3%
359	Cerebellar Neoplasms	1.3%
360	Nasopharyngeal Neoplasms	1.2%
361	Colorectal Neoplasms	1.2%
362	Radicular Cyst	1.1%
363	Appendiceal Neoplasms	1.1%
364	Colonic Neoplasms	1.1%
365	Rectal Neoplasms	1.1%
366	Paranasal Sinus Neoplasms	1.1%
367	Maxillary Sinus Neoplasms	0.9%
368	Anus Neoplasms	0.9%
369	Sigmoid Neoplasms	0.9%

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