MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Meige Syndrome

(UMLS:C0025183)

Definition:: A syndrome characterized by orofacial DYSTONIA; including BLEPHAROSPASM; forceful jaw opening; lip retraction; platysma muscle spasm; and tongue protrusion. It primarily affects older adults, with an incidence peak in the seventh decade of life. (From Adams et al., Principles of Neurology, 6th ed, p108)
UMLS ID:: C0025183
MeSH ID:: D008538

Classification:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.140.079.590|C10.228.662.300.500

Synonym(s)

Meige Syndrome

Blepharospasm - oromandibular dystonia

Brueghel syndrome

Meige syndrome

Meige's syndrome

meige syndrome

meige's syndrome

meiges syndrome

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Biperiden	12404689	CTD
2	Chlorpromazine	2887231	CTD
3	Clonazepam	11555353	CTD
4	Fluvoxamine	18081639	CTD
5	Haloperidol	2894781	CTD
6	Quetiapine Fumarate	12404689	CTD
7	Ranitidine	9918370	CTD
8	Risperidone	10618045 18081639	CTD
9	Sulpiride	12163987	CTD
10	Tetrabenazine	3279337	CTD
11	Thioridazine	2894781	CTD
12	Tiapamil Hydrochloride	4074571	CTD
13	benserazide, levodopa drug combination	6842240	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Parkinsonian Disorders	53.7%
2	Multiple System Atrophy	45.3%
3	Dystonia Musculorum Deformans	42.4%
4	Encephalomyelitis	40%
5	Parkinson Disease	37.4%
6	Meningoencephalitis	37%
7	Basal Ganglia Cerebrovascular Disease	36.4%
8	Lewy Body Disease	36.1%
9	Subdural Effusion	34.1%
10	Meningitis	33.3%
11	Pachymeningitis	33.3%
12	Spinal Cord Diseases	33.3%
13	Akinetic Mutism	32.6%
14	Anoxic Encephalopathy	32.6%
15	Brain Damage, Chronic	32.6%
16	Cerebellar Diseases	32.6%
17	Encephalitis	32.6%
18	Encephalomalacia	32.6%
19	Epilepsy	32.6%
20	Hydrocephalus	32.6%
21	Congenital Hydrocephalus	32.6%
22	Hypothalamic Diseases	32.6%
23	Thalamic Diseases	32.6%
24	Intracranial Hypertension	32.6%
25	Aura	32.6%
26	Leukoencephalopathy	32.6%
27	Essential Tremor	32.6%
28	Neuroaxonal Dystrophies	32.6%
29	Familial Tremor	32.6%
30	Headache Disorders	32.6%
31	Intracranial Hypotension	32.6%
32	Brain Edema	32.6%
33	Brain Hypoxia	32.6%
34	Aqueductal Stenosis	32.6%
35	Striatonigral Degeneration	30.7%
36	Neuroleptic Malignant Syndrome	30.5%
37	Myelitis	29.5%
38	Pneumocephalus	29.5%
39	Progressive supranuclear palsy	28.9%
40	Ocular Motility Disorders	28.2%
41	Cyclophoria	28.2%
42	Posterior Leukoencephalopathy Syndrome	28.1%
43	Posterior reversible encephalopathy syndrome	28.1%
44	Huntington Disease	27.9%
45	Dandy-Walker Syndrome	27.5%
46	Asterixis	26.7%
47	Ballismus	26.7%
48	Brain Abscess	26.5%
49	Shy-Drager Syndrome	26.5%
50	Central Nervous System Infection	26.3%
51	Epidural Abscess	26.1%
52	MPTP Poisoning	25.9%
53	Dementia, Vascular	25.9%
54	Cerebral Ventriculitis	25.8%
55	Torticollis	25.7%
56	Brain Diseases, Metabolic	25%
57	Cerebrovascular Disorders	25%
58	Cerebrovascular Insufficiency	25%
59	Dementia	25%
60	Marchiafava-Bignami Disease	24.8%
61	Myoclonic Epilepsy	24%
62	Epilepsy, Temporal Lobe	24%
63	Epilepsy, Rolandic	24%
64	Benign Rolandic Epilepsy	24%
65	Brain Injuries	23.7%
66	Epilepsy, Post-Traumatic	23.7%
67	Brain Neoplasms	23.5%
68	Prion Diseases	23.3%
69	Vascular Headaches	22.7%
70	Hypoxia-Ischemia, Brain	22.5%
71	Hepatolenticular Degeneration	21.9%
72	Leukomalacia, Periventricular	21.7%
73	Basal Ganglia Hemorrhage	21.7%
74	Cerebral Palsy	21.5%
75	Epilepsies, Partial	21.5%
76	Epilepsy, Generalized	21.5%
77	Pseudotumor Cerebri	21.5%
78	Hypertensive Encephalopathy	21.5%
79	Simple Partial Seizures	21.5%
80	Epilepsy, Reflex	21.5%
81	Headache Disorders, Primary	21.5%
82	Headache Disorders, Secondary	21.5%
83	Medication overuse headache	21.5%
84	Stiff-Person Syndrome	21.3%
85	Brain Death	21.1%
86	Cranial nerve diseases	20.9%
87	Demyelinating Diseases	20.9%
88	Demyelination	20.9%
89	Neuromuscular Diseases	20.9%
90	Chronobiology Disorders	20.9%
91	Creutzfeldt-Jakob disease	20.8%
92	Cerebellar Neoplasms	20.2%
93	Juvenile Myoclonic Epilepsy	19.9%
94	Myoclonic Epilepsies, Progressive	19.9%
95	Myelinolysis, Central Pontine	19.9%
96	Spinal Muscular Atrophy	19.7%
97	Progressive Muscular Atrophy	19.7%
98	Meningitis, Bacterial	19.6%
99	Meningitis, Fungal	19.6%
100	Arachnoiditis	19.6%
101	Aseptic Meningitis	19.6%
102	Syringomyelia	19.6%
103	Pneumorrhachis	19.6%
104	Spinal Cord Injuries	19.4%
105	Akathisia, Drug-Induced	19.1%
106	Amblyopia	18.6%
107	Poliomyelitis	18.6%
108	Putaminal Hemorrhage	18.3%
109	Leukoencephalopathy, Progressive Multifocal	18.2%
110	Subacute Combined Degeneration	18.1%
111	Limbic Encephalitis	17.7%
112	Lupus Vasculitis, Central Nervous System	17.2%
113	Pituitary Diseases	17.1%
114	Presenile dementia	17%
115	Senile dementia	17%
116	Motor Neuron Disease	16.9%
117	Amyotrophic Lateral Sclerosis	16.9%
118	Chorea	16.9%
119	Brain Diseases	16.7%
120	Movement Disorders	16.7%
121	Trauma, Nervous System	16.4%
122	Pituitary Apoplexy	16.3%
123	Chronic Fatigue Syndrome	16.3%
124	Carotid Artery Diseases	16.3%
125	Brain Ischemia	16.3%
126	Cerebrovascular accident	16.3%
127	Kluver-Bucy Syndrome	16.3%
128	Vasospasm, Intracranial	16.3%
129	Intracranial Arterial Diseases	16.3%
130	Post-Traumatic Headache	16%
131	Tension Headache	16%
132	Epilepsy, Complex Partial	16%
133	Migraine Disorders	16%
134	Abdominal Migraine	16%
135	Status Migrainosus	16%
136	Cervicogenic Headache	16%
137	Brain Infarction	16%
138	Nervous System Neoplasms	15.8%
139	Neurologic Manifestations	15.8%
140	Neurotoxicity Syndromes	15.8%
141	Spinal Cord Neoplasms	15.7%
142	Brain Injuries, Diffuse	15.5%
143	Traumatic Brain Injury	15.5%
144	Cerebellar Ataxia	15.4%
145	Supratentorial Neoplasms	15.4%
146	Lafora Disease	15.3%
147	Unverricht-Lundborg Syndrome	15.3%
148	Leukoencephalitis, Acute Hemorrhagic	15.3%
149	Amnesia, Transient Global	15.3%
150	Dyskinesia, Drug-Induced	15%
151	Central Nervous System Fungal Infections	15%
152	Conus Medullaris Syndrome	15%
153	Spinal Cord Vascular Diseases	15%
154	Ophthalmoplegic Migraine	14.8%
155	Toxoplasmosis, Cerebral	14.7%
156	Persistent Vegetative State	14.7%
157	Pituitary Adenoma	14.7%
158	Pituitary Neoplasms	14.7%
159	Encephalomyelitis, Acute Disseminated	14.6%
160	Carotid Artery Injuries	14.6%
161	Brain Hemorrhage, Traumatic	14.5%
162	Friedreich Ataxia	14.3%
163	Vasculitis, Central Nervous System	14.2%
164	Paraneoplastic Cerebellar Degeneration	14.1%
165	Infarction, Middle Cerebral Artery	13.9%
166	Infarction, Anterior Cerebral Artery	13.9%
167	Infarction, Posterior Cerebral Artery	13.9%
168	Myelitis, Transverse	13.7%
169	Tuberculosis, Meningeal	13.7%
170	Restless Legs Syndrome	13.5%
171	Polyradiculoneuropathy	13.4%
172	Polyradiculoneuritis	13.4%
173	Cluster Headache	13.3%
174	Migraine with Aura	13.3%
175	Autonomic Dysreflexia	13.3%
176	Familial Hemiplegic Migraine	13.3%
177	Chronic Paroxysmal Hemicrania	13.3%
178	Complex Regional Pain Syndromes	13.3%
179	SUNCT Syndrome	13.3%
180	Paroxysmal Hemicrania	13.3%
181	Cerebral Infarction	13.3%
182	Brain Stem Infarctions	13.3%
183	Miller Fisher Syndrome	13.2%
184	Reye Syndrome	13.1%
185	Intracranial Embolism and Thrombosis	13%
186	Hepatic Encephalopathy	13%
187	Sleep Wake Disorders	12.9%
188	Canavan Disease	12.8%
189	Alexander Disease	12.8%
190	Moyamoya Disease	12.6%
191	Opsoclonus-Myoclonus Syndrome	12.5%
192	Empty Sella Syndrome	12.3%
193	Hyperpituitarism	12.3%
194	Hypopituitarism	12.3%
195	Hypophysitis	12.3%
196	Tardive Dyskinesia	12.2%
197	Central Nervous System Bacterial Infections	12.2%
198	Cerebral Arterial Diseases	12%
199	Vertebrobasilar Insufficiency	12%
200	Basilar Artery Stenosis	12%
201	Vertebral Artery Stenosis	12%
202	Intracranial Hemorrhage, Hypertensive	12%
203	Transient Cerebral Ischemia	12%
204	Scrapie	11.9%
205	Central Cord Syndrome	11.9%
206	Lateral Medullary Syndrome	11.9%
207	Diffuse Axonal Injury	11.5%
208	Brain Stem Neoplasms	11.5%
209	Meningitis, Cryptococcal	11.3%
210	Meningitis, Listeria	11.3%
211	Meningitis, Haemophilus	11.2%
212	Meningitis, Pneumococcal	11.2%
213	Mitochondrial Encephalomyopathies	11.2%
214	Dysautonomia	11.1%
215	Subacute Sclerosing Panencephalitis	11.1%
216	Vagus Nerve Disorder	11.1%
217	Glossopharyngeal Neuralgia	11.1%
218	Abducens Nerve Diseases	11.1%
219	Heavy Metal Poisoning, Nervous System	11.1%
220	Neuromuscular Junction Diseases	11.1%
221	Tauopathies	11.1%
222	Trochlear Nerve Diseases	11.1%
223	Peripheral Nervous System Diseases	11.1%
224	Brain Diseases, Metabolic, Inborn	10.9%
225	Peripheral Nerve Injuries	10.8%
226	Myasthenia Gravis	10.7%
227	Subarachnoid Hemorrhage, Traumatic	10.3%
228	Carotid Artery, Internal, Dissection	10.3%
229	Frontotemporal dementia	10.2%
230	Hyperprolactinemia	10.1%
231	Subclavian Steal Syndrome	10%
232	Pick Disease of the Brain	10%
233	Progressive bulbar palsy	9.8%
234	Bulbar palsy	9.8%
235	Guillain-Barre Syndrome	9.8%
236	Basal Ganglia Diseases	9.8%
237	Writer's Cramp	9.8%
238	Spinal Cord Ischemia	9.8%
239	Vertebral Artery Dissection	9.7%
240	Auditory Perceptual Disorders	9.7%
241	Carotid Stenosis	9.7%
242	Intracranial Aneurysm	9.7%
243	Meige Syndrome	9.7%
244	Brain Contusion	9.7%
245	Intracranial Arteriosclerosis	9.6%
246	Cerebral Atherosclerosis	9.6%
247	Subarachnoid Hemorrhage	9.6%
248	Cerebral Arteriosclerosis	9.6%
249	Cerebral Hemorrhage	9.6%
250	MELAS Syndrome	9.6%
251	Tuberculosis, Central Nervous System	9.6%
252	Cerebral Thrombosis	9.6%
253	Intracranial Embolism	9.6%
254	Intracranial Thrombosis	9.6%
255	Choroid Plexus Papilloma	9.5%
256	Wernicke Encephalopathy	9.3%
257	AIDS Dementia Complex	9.3%
258	Ataxia Telangiectasia	9.3%
259	Adrenoleukodystrophy	9.2%
260	Sleep Disorders, Circadian Rhythm	9.2%
261	Lambert-Eaton Myasthenic Syndrome	9.1%
262	Causalgia	9.1%
263	Brain Concussion	8.9%
264	Botulism	8.8%
265	Central Nervous System Cysts	8.8%
266	Myopathy	8.8%
267	Optic Neuropathy	8.8%
268	Olfactory Nerve Injuries	8.7%
269	West Nile Fever	8.5%
270	Facial Nerve Diseases	8.5%
271	Craniocerebral Trauma	8.5%
272	Parasomnia	8.5%
273	Dyssomnias	8.5%
274	Vestibulocochlear Nerve Diseases	8.3%
275	Decerebrate State	8.3%
276	Hemiparesis	8.3%
277	Hydranencephaly	8.3%
278	Meningism	8.3%
279	Neural Tube Defects	8.3%
280	Paresis	8.3%
281	Seizures	8.3%
282	Sensation Disorders	8.3%
283	Tethered Cord Syndrome	8.3%
284	Central Nervous System Neoplasms	8.3%
285	Complex partial seizures	8.3%
286	Iniencephaly	8.3%
287	Craniorachischisis	8.3%
288	Exencephaly	8.3%
289	Monoparesis	8.3%
290	Septo-Optic Dysplasia	8.3%
291	Cortical Dysplasia	8.3%
292	Neurogenic Inflammation	8.3%
293	Gait Disorders, Neurologic	8.3%
294	Neuromuscular Manifestations	8.3%
295	Malformations of Cortical Development	8.3%
296	Kernicterus	8.3%
297	Sweating, Gustatory	8.3%
298	Auriculotemporal Syndrome	8.3%
299	Alice in Wonderland Syndrome	8.2%
300	Acromegaly	8.1%
301	Reflex Sympathetic Dystrophy	8.1%
302	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	8.1%
303	Nocturnal Myoclonus Syndrome	8.1%
304	Carotid Artery Thrombosis	8%
305	Cerebral Amyloid Angiopathy	8%
306	Sinus Thrombosis, Intracranial	8%
307	Multiple Sclerosis	7.8%
308	Neuroaspergillosis	7.8%
309	Neuromyelitis Optica	7.8%
310	Horner Syndrome	7.7%
311	Giant Cell Arteritis	7.6%
312	Temporal Arteritis	7.6%
313	Facial Nerve Injuries	7.5%
314	Anterior Spinal Artery Syndrome	7.2%
315	Cavernous Sinus Thrombosis	7.1%
316	Sagittal Sinus Thrombosis	7.1%
317	Refsum Disease	6.9%
318	Pupil Disorders	6.9%
319	Neurobehavioral Manifestations	6.9%
320	Pseudorabies	6.9%
321	Paraneoplastic Encephalomyelitis	6.8%
322	Uveomeningoencephalitic Syndrome	6.7%
323	Ophthalmoplegia	6.6%
324	External Ophthalmoplegia	6.6%
325	Sturge-Weber Syndrome	6.6%
326	Vertigo	6.6%
327	Alcohol-Induced Disorders, Nervous System	6.6%
328	Hematoma, Subdural	6.6%
329	Hematoma, Epidural, Cranial	6.6%
330	Jet Lag Syndrome	6.6%
331	Neuritis	6.5%
332	Polyneuritis	6.5%
333	Radiculitis	6.5%
334	Polyneuropathy	6.5%
335	Mononeuritis	6.5%
336	Mononeuropathies	6.5%
337	Brachial Plexus Neuropathies	6.5%
338	Radiculopathy	6.5%
339	Mononeuropathy Multiplex	6.5%
340	Nerve Root Compression	6.5%
341	Myasthenia Gravis, Autoimmune, Experimental	6.5%
342	Acrodynia	6.5%
343	Neurosyphilis	6.5%
344	Brachial Plexus Neuritis	6.5%
345	Neuralgic Amyotrophy	6.5%
346	Tuberous Sclerosis	6.1%
347	Galactosemias	6%
348	Urea Cycle Disorders, Inborn	6%
349	Tyrosinemias	6%
350	Charcot-Marie-Tooth Disease	6%
351	Nelson Syndrome	6%
352	Fabry Disease	6%
353	Toxoplasmosis, Congenital	5.9%
354	Malaria, Cerebral	5.9%
355	Neurocysticercosis	5.8%
356	Prolactinoma	5.8%
357	Growth Hormone-Secreting Pituitary Adenoma	5.8%
358	Vocal Cord Paralysis	5.7%
359	Voice Disorders	5.7%
360	Voice Disturbance	5.7%
361	Hematoma, Subdural, Intracranial	5.7%
362	Hematoma, Subdural, Chronic	5.7%
363	Hematoma, Subdural, Acute	5.7%
364	Tarsal Tunnel Syndrome	5.6%
365	Cauda Equina Syndrome	5.6%
366	Smith-Magenis syndrome	5.6%
367	Coma, Post-Head Injury	5.5%
368	Dural Arteriovenous Fistula	5.5%
369	Lyme Neuroborreliosis	5.5%
370	Myotonia Congenita	5.5%
371	Cerebrospinal Fluid Otorrhea	5.4%
372	Cerebrospinal Fluid Rhinorrhea	5.4%
373	Homocystinuria	5.4%
374	Neuritis, Autoimmune, Experimental	5.4%
375	Gait Ataxia	5.4%
376	Leigh Disease	5.4%
377	Multiple Sclerosis, Chronic Progressive	5.1%
378	Multiple Sclerosis, Relapsing-Remitting	5.1%
379	Myositis	5%
380	Optic Atrophy	5%
381	Optic Neuritis	5%
382	Papilledema	5%
383	Strabismus	5%
384	Tolosa-Hunt Syndrome	5%
385	Isaacs syndrome	5%
386	Arsenic Poisoning	5%
387	Myotonic Disorders	5%
388	Myasthenic Syndromes, Congenital	5%
389	Diabetic Neuropathies	4.9%
390	Facial Injuries	4.9%
391	Facial Neuralgia	4.9%
392	Diabetic Amyotrophy	4.9%
393	Diabetic Autonomic Neuropathy	4.9%
394	Sleep Talking	4.9%
395	Manganese Poisoning	4.9%
396	Sleep Disorders, Intrinsic	4.9%
397	Orthostatic intolerance	4.9%
398	Alcohol Withdrawal Seizures	4.9%
399	Anosmia	4.9%
400	Ataxia	4.9%
401	Athetosis	4.9%
402	Catalepsy	4.9%
403	Dystonia	4.9%
404	Hemiplegia	4.9%
405	Locked-In Syndrome	4.9%
406	Meningeal Neoplasms	4.9%
407	Meningomyelocele	4.9%
408	Muscle Hypertonia	4.9%
409	Muscle hypotonia	4.9%
410	Myoclonus	4.9%
411	Myotonia	4.9%
412	Neuralgia	4.9%
413	Paraplegia	4.9%
414	Pseudobulbar Palsy	4.9%
415	Quadriplegia	4.9%
416	Spasm	4.9%
417	Spastic Paraplegia	4.9%
418	Status Epilepticus	4.9%
419	Taste Disorders	4.9%
420	Tremor	4.9%
421	Spina Bifida	4.9%
422	Monoplegia	4.9%
423	Hypokinesia	4.9%
424	Paraparesis	4.9%
425	Bradykinesia	4.9%
426	Waxy flexibility	4.9%
427	Action Tremor	4.9%
428	Resting Tremor	4.9%
429	Dysosmia	4.9%
430	Quadriparesis	4.9%
431	Mercury Poisoning, Nervous System	4.9%
432	Olfaction Disorders	4.9%
433	Myokymia	4.9%
434	Lead Poisoning, Nervous System	4.9%
435	Vestibular Neuronitis	4.9%
436	Somatosensory Disorders	4.9%
437	Neuropathic pain	4.9%
438	Hyperkinesia	4.9%
439	Intention tremor	4.9%
440	Menkes Kinky Hair Syndrome	4.8%
441	Waterhouse-Friderichsen Syndrome	4.8%
442	Myotonic Dystrophy	4.7%
443	Reflex, Abnormal	4.7%
444	Hyporeflexia	4.7%
445	Hyperreflexia	4.7%
446	Akathisia	4.6%
447	Restlessness	4.6%
448	Psychomotor Agitation	4.6%
449	Carpal Tunnel Syndrome	4.5%
450	neurofibroma	4.5%
451	Sciatica	4.5%
452	Carbamoyl-Phosphate Synthase I Deficiency Disease	4.4%
453	Sciatic Neuropathy	4.3%
454	Ulnar Neuropathies	4.3%
455	Lesion of Sciatic Nerve	4.3%
456	Ulnar Neuritis	4.3%
457	Radial nerve compression	4.3%
458	Radial Tunnel Syndrome	4.3%
459	Peroneal Neuropathies	4.3%
460	Radial Neuropathy	4.3%
461	Median Neuropathy	4.3%
462	Sciatic Nerve Palsy	4.3%
463	Femoral Neuropathy	4.3%
464	Tibial Neuropathy	4.3%
465	Ulnar Nerve Palsy	4.3%
466	Postural Orthostatic Tachycardia Syndrome	4.3%
467	Radial nerve palsy	4.3%
468	Hand-Arm Vibration Syndrome	4.2%
469	Gait Apraxia	4.1%
470	Vision Disorders	4.1%
471	Zellweger Syndrome	4.1%
472	Metamorphopsia	4.1%
473	Visual Impairment	4.1%
474	Fibromyalgia	4.1%
475	Optic Neuropathy, Ischemic	4.1%
476	Anterior Ischemic Optic Neuropathy	4.1%
477	Medial Tibial Stress Syndrome	4.1%
478	Optic Nerve Glioma	4%
479	Facial Hemiatrophy	4%
480	Melkersson-Rosenthal Syndrome	4%
481	Mitochondrial Myopathies	4%
482	Glycogen storage disease type II	4%
483	Anisocoria	4%
484	Confusion	4%
485	Facial paralysis	4%
486	Lethargy	4%
487	Memory Disorders	4%
488	Muscle Cramp	4%
489	Perceptual Disorders	4%
490	Psychomotor Disorders	4%
491	Tonic Pupil	4%
492	Eosinophilia-Myalgia Syndrome	4%
493	Anhedonia	4%
494	Disorientation	4%
495	Facial Paresis	4%
496	Memory Loss	4%
497	Hemisensory Neglect	4%
498	Dysacusis	4%
499	Sleep Bruxism	3.9%
500	Anencephaly	3.9%
501	Meningocele	3.9%
502	Muscular Atrophy	3.9%
503	Respiratory Paralysis	3.9%
504	Encephalocele	3.9%
505	Tetany	3.9%
506	Cubital Tunnel Syndrome	3.8%
507	Alstrom Syndrome	3.8%
508	Amyloid Neuropathies, Familial	3.6%
509	Acoustic Neuroma	3.5%
510	Duane Retraction Syndrome	3.4%
511	Consciousness Disorders	3.4%
512	Mental Retardation	3.4%
513	Muscle Weakness	3.4%
514	Depressed Level of Consciousness	3.4%
515	Mental deficiency	3.4%
516	Intellectual Disability	3.4%
517	Mobius Syndrome	3.3%
518	Bell Palsy	3.3%
519	Catatonia	3.3%
520	Herpes Zoster Oticus	3.3%
521	Thoracic Outlet Syndrome	3.3%
522	Familial Periodic Paralysis	3.3%
523	Aphonia	3.3%
524	Sleep Deprivation	3.3%
525	Dysphonia	3.3%
526	Esotropia	3.3%
527	Exotropia	3.3%
528	Hypotension, Orthostatic	3.3%
529	Sleep Apnea Syndromes	3.3%
530	Polymyositis	3.3%
531	Post-Exercise Hypotension	3.3%
532	Gaucher Disease	3.2%
533	Disorders of Excessive Somnolence	3.2%
534	Sleep Initiation and Maintenance Disorders	3.2%
535	Night Terrors	3.2%
536	Somnambulism	3.2%
537	Trigeminal Nerve Disorder	3.2%
538	Transient Insomnia	3.2%
539	Sleep Paralysis	3.2%
540	Chronic Insomnia	3.2%
541	REM Sleep Behavior Disorder	3.2%
542	Hypersomnia	3.2%
543	Dermal Sinus	3.2%
544	Dysgeusia	3.2%
545	Formication	3.2%
546	Hyperalgesia	3.2%
547	Hyperesthesia	3.2%
548	Hypesthesia	3.2%
549	Language Disorders	3.2%
550	Numbness	3.2%
551	Paresthesia	3.2%
552	Paraparesis, Spastic	3.2%
553	Spina Bifida Cystica	3.2%
554	Trismus	3.2%
555	Spina Bifida Occulta	3.2%
556	Epilepsia Partialis Continua	3.2%
557	Hypogeusia	3.2%
558	Meningeal Carcinomatosis	3.2%
559	Brown-Sequard Syndrome	3.2%
560	Lissencephaly	3.2%
561	Polymicrogyria	3.2%
562	Pachygyria	3.2%
563	Schizencephaly	3.2%
564	Lockjaw	3.2%
565	Allodynia	3.2%
566	Lead Poisoning, Nervous System, Childhood	3.2%
567	Lead Poisoning, Nervous System, Adult	3.2%
568	Periventricular Nodular Heterotopia	3.2%
569	Ageusia	3.2%
570	Polyradiculopathy	3.2%
571	Classical Lissencephalies and Subcortical Band Heterotopias	3.2%
572	Tay-Sachs Disease	3%
573	Myalgia	2.8%
574	Niemann-Pick Disease, Type C	2.8%
575	Neuronal Ceroid-Lipofuscinoses	2.8%
576	Alexia	2.7%
577	Dyslexia	2.7%
578	Eye Injuries	2.7%
579	Muscular Dystrophy	2.6%
580	Congenital nystagmus	2.6%
581	Orbital Myositis	2.6%
582	Diplopia	2.6%
583	Muscle Rigidity	2.6%
584	Muscle Spasticity	2.6%
585	Scotoma	2.6%
586	Photophobia	2.6%
587	Cogwheel Rigidity	2.6%
588	Hemifacial Spasm	2.6%
589	Amaurosis	2.6%
590	Blindness	2.6%
591	Nuchal Rigidity	2.6%
592	Pyomyositis	2.6%
593	Agnosia	2.6%
594	Apraxias	2.6%
595	Hallucinations	2.6%
596	Hemianopsia	2.6%
597	Hyperacusis	2.6%
598	Tinnitus	2.6%
599	Visual Agnosia	2.6%
600	Anosognosia	2.6%
601	Wernicke-Korsakoff Syndrome	2.6%
602	Phonophobia	2.6%
603	Hearing Loss	2.6%
604	Sarcopenia	2.6%
605	Optic Atrophy, Hereditary, Leber	2.5%
606	Aicardi's syndrome	2.5%
607	Neurofibrosarcoma	2.5%
608	Hoarseness	2.5%
609	Cockayne Syndrome	2.5%
610	Alcohol Withdrawal Delirium	2.5%
611	Kearns-Sayre syndrome	2.4%
612	Sleep Apnea, Obstructive	2.4%
613	Sleep Apnea, Central	2.4%
614	Narcolepsy	2.4%
615	Trigeminal Neuralgia	2.4%
616	Kleine-Levin Syndrome	2.4%
617	Agraphia	2.4%
618	Anomia	2.4%
619	Cluttering	2.4%
620	Language Development Disorders	2.4%
621	Speech Disorders	2.4%
622	Syncope	2.4%
623	Stupor	2.4%
624	Dysgraphia	2.4%
625	Presyncope	2.4%
626	Dyslalia	2.4%
627	Amnesia	2.2%
628	Delirium	2.2%
629	Dissociative Amnesia	2.2%
630	Color blindness	2.2%
631	Global Amnesia	2.2%
632	Holoprosencephaly	2.2%
633	Cri-du-Chat Syndrome	2.2%
634	Down Syndrome	2.2%
635	Trisomy 21	2.2%
636	POEMS Syndrome	2.2%
637	Meningioma	2.2%
638	Williams Syndrome	2.2%
639	Microcephaly	2.2%
640	Macrocephaly	2.2%
641	Hypokalemic periodic paralysis	2.2%
642	Porencephaly	2.1%
643	Cataplexy	2%
644	Aphasia	2%
645	Articulation Disorders	2%
646	Echolalia	2%
647	Stuttering	2%
648	Dysphasia	2%
649	Eye Burns	2%
650	Welander Distal Myopathy	1.9%
651	Amaurosis Fugax	1.9%
652	Blindness, Cortical	1.9%
653	Dyscalculia	1.9%
654	Rett Syndrome	1.9%
655	Deafness	1.9%
656	Hearing Loss, Sudden	1.9%
657	Gerstmann Syndrome	1.9%
658	Hearing Loss, Bilateral	1.9%
659	Hearing Loss, High-Frequency	1.9%
660	Hearing Loss, Mixed Conductive-Sensorineural	1.9%
661	Prosopagnosia	1.9%
662	Apraxia, Ideomotor	1.9%
663	Charles Bonnet Syndrome	1.9%
664	Hearing Loss, Unilateral	1.9%
665	Complete Hearing Loss	1.9%
666	Alien Hand Syndrome	1.9%
667	Deaf Mutism	1.9%
668	Prader-Willi Syndrome	1.9%
669	Phantom pain	1.8%
670	Phantom Limb Pain	1.8%
671	Dysarthria	1.8%
672	Dermatomyositis	1.7%
673	Corneal Scar	1.7%
674	Mutism	1.6%
675	Selective Mutism	1.6%
676	Muscular Dystrophy, Duchenne	1.6%
677	Retrograde amnesia	1.6%
678	Amnesia, Anterograde	1.6%
679	Rubinstein-Taybi Syndrome	1.5%
680	Alexia, Pure	1.4%
681	Fragile X Syndrome	1.4%
682	Corneal Perforation	1.3%
683	Mucopolysaccharidosis II	1%

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