MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Lymphangioma

(UMLS:C0024221)

Definition:: A benign tumor resulting from a congenital malformation of the lymphatic system. Lymphangioendothelioma is a type of lymphangioma in which endothelial cells are the dominant component.
UMLS ID:: C0024221
MeSH ID:: D008202

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.375.450

Synonym(s)

Lymphangioma

Benign lymphangioma

Congenital lymphangioma

LYMPHANGIOMA

LYMPHANGIOMA, BENIGN

Lymphangioma NOS

Lymphangioma morphology

Lymphangioma of unspecified site

Lymphangioma, NOS

10.

Lymphangioma, any site

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Leflunomide	FAERS: 2		US FAERS
2	Ondansetron	FAERS: 2		US FAERS
3	Paroxetine	FAERS: 2		US FAERS
4	Sorafenib	FAERS: 2		US FAERS
5	Erlotinib Hydrochloride	FAERS: 1		US FAERS
6	Glatiramer Acetate	FAERS: 1		US FAERS
7	Glatiramer Acetate	FAERS: 1		US FAERS
8	Hydroxychloroquine	FAERS: 1		US FAERS
9	Norgestrel	FAERS: 1		US FAERS
10	Sitagliptin Phosphate	FAERS: 1		US FAERS
11	Tacrolimus	FAERS: 1		US FAERS
12	Tamoxifen	FAERS: 1		US FAERS
13	Valproic Acid	FAERS: 1		US FAERS
14	Vincristine	FAERS: 1		US FAERS
15	eribulin	FAERS: 1		US FAERS
16	Diclofenac			OFFSIDES
17	Isosorbide Dinitrate			OFFSIDES
18	Sodium Tetradecyl Sulfate		17625033	CTD
19	Telmisartan			OFFSIDES
20	Theophylline			OFFSIDES
21	alfacalcidol			OFFSIDES
22	ferrous fumarate			OFFSIDES
23	fudosteine			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	lymphangiosarcoma	40.7%
2	leukemia	31%
3	Neoplasms, Germ Cell and Embryonal	31%
4	Neoplasms, Glandular and Epithelial	31%
5	Germ Cell Cancer	31%
6	Neuroectodermal Tumors	26.7%
7	Neoplasms, Neuroepithelial	24.6%
8	Gliomatosis cerebri	24.6%
9	Carcinosarcoma	23.1%
10	Hemangiosarcoma	23.1%
11	melanoma	22%
12	Histiocytic Disorders, Malignant	20.5%
13	Adenoma	20%
14	Ameloblastoma	20%
15	Angiokeratoma	20%
16	Carcinoma	20%
17	Chordoma	20%
18	Hemangioma	20%
19	hemangiopericytoma	20%
20	Mesenchymoma	20%
21	Nevus	20%
22	Teratoma	20%
23	Hepatoblastoma	20%
24	Mixed Tumor, Mullerian	20%
25	Germinoma	20%
26	Teratocarcinoma	20%
27	Angiofibroma	20%
28	Sarcoma	20%
29	Epithelioma	20%
30	Basal cell carcinoma	19.6%
31	Carcinoma, Papillary	19.6%
32	Squamous cell carcinoma	19.6%
33	Chondrosarcoma	19.6%
34	Craniopharyngioma	19.6%
35	Cystadenoma	19.6%
36	leiomyosarcoma	19.6%
37	liposarcoma	19.6%
38	Mesothelioma	19.6%
39	synovial sarcoma	19.6%
40	Neuroectodermal Tumor, Melanotic	19.6%
41	Angiomyolipoma	19.6%
42	Clear Cell Sarcoma of Soft Tissue	19.6%
43	Alveolar Soft Part Sarcoma	19.6%
44	Neuroendocrine Tumors	19.6%
45	Sarcoma, Myeloid	19.6%
46	Carcinoma, Basal Cell	19.6%
47	Lymphangioleiomyomatosis	19.5%
48	Adenoma, Acidophil	19.4%
49	Ganglioneuroma	19.4%
50	Glioma	19.4%
51	Malignant Glioma	19.4%
52	Medulloblastoma	19.1%
53	Carcinoma 256, Walker	18.7%
54	Hamartoma	18.5%
55	Neoplasms, Hormone-Dependent	18.5%
56	Neoplasms, Multiple Primary	18.5%
57	Paraneoplastic Syndromes	18.5%
58	Precancerous Conditions	18.5%
59	Neoplasms, Second Primary	18.5%
60	Carcinoid Tumor	18.1%
61	Neurilemmoma	18.1%
62	Hutchinson's Melanotic Freckle	18.1%
63	Melanoma, Amelanotic	18.1%
64	Cystadenocarcinoma	17.8%
65	Fibrosarcoma	17.8%
66	Osteosarcoma	17.8%
67	Mucoepidermoid Carcinoma	17.8%
68	Meningioma	17.4%
69	Leukemia, Plasma Cell	17.2%
70	Adenofibroma	17%
71	Fibroadenoma	17%
72	Malignant Fibrous Histiocytoma	17%
73	Carcinoma, Ehrlich Tumor	16.9%
74	Dermoid Cyst	16.9%
75	Carcinoma, Lewis Lung	16.9%
76	Astrocytoma	16.8%
77	Ependymoma	16.8%
78	oligodendroglioma	16.8%
79	Ganglioglioma	16.8%
80	gliosarcoma	16.8%
81	Anaplastic astrocytoma	16.8%
82	Anaplastic Oligodendroglioma	16.8%
83	Malignant Carcinoid Syndrome	16.2%
84	Bowen's Disease	16.1%
85	Paraganglioma	16.1%
86	Rhabdomyosarcoma	16.1%
87	Giant Cell Tumor of Bone	16.1%
88	Composite Lymphoma	15.8%
89	Glioblastoma	15.5%
90	Neuroblastoma	15.5%
91	Glioblastoma Multiforme	15.5%
92	Melanoma, Experimental	15.5%
93	Dermatofibrosarcoma	15.3%
94	Dermatofibrosarcoma Protuberans	15.3%
95	Lymphoma	15.3%
96	Trophoblastic Neoplasms	15.3%
97	Leukemia, Experimental	15.1%
98	Ganglioneuroblastoma	14.9%
99	Adenocarcinoma	14.8%
100	Carcinoma in Situ	14.8%
101	Carcinoma, Transitional Cell	14.8%
102	Phyllodes Tumor	14.8%
103	Dysgerminoma	14.8%
104	Hemangioendothelioma	14.8%
105	Lipoma	14.8%
106	Myoma	14.8%
107	Myxoma	14.8%
108	Neuroma	14.8%
109	Papilloma	14.8%
110	Pseudomyxoma Peritonei	14.8%
111	Seminoma	14.8%
112	Papillomatosis	14.8%
113	Angiolipoma	14.8%
114	Myelolipoma	14.8%
115	Neoplasms, Bone Tissue	14.8%
116	Neoplasms, Fibrous Tissue	14.8%
117	Smooth Muscle Tumor	14.8%
118	Adenomatosis, Pulmonary	14.8%
119	Adenomatous Polyps	14.8%
120	Carcinoma, Large Cell	14.8%
121	Carcinoma, Small Cell	14.8%
122	Desmoplastic Small Round Cell Tumor	14.8%
123	Chondroma	14.8%
124	Enchondroma	14.8%
125	Pheochromocytoma	14.4%
126	Alveolar rhabdomyosarcoma	14.4%
127	Leukemia L1210	14.3%
128	Leukemia P388	14.3%
129	Acanthoma	14.3%
130	Choriocarcinoma	13.4%
131	Carcinoma, Lobular	13.4%
132	Plasmacytoma	13.3%
133	Malignant histiocytosis	13.2%
134	Histiocytic sarcoma	13.2%
135	Sarcoma 180	12.6%
136	Endometrial Stromal Sarcoma	12.6%
137	Sarcoma, Experimental	12.5%
138	Carcinoid Heart Disease	12.4%
139	Thymoma	12.4%
140	Leukemia, Radiation-Induced	12.2%
141	Adenoid Cystic Carcinoma	12.2%
142	Cyst	12.2%
143	fibroma	12.2%
144	Fibromatosis	12.2%
145	Neoplastic Processes	12.2%
146	Neoplastic Syndromes, Hereditary	12.2%
147	Osteoblastoma	12.2%
148	Osteoma	12.2%
149	Pregnancy Complications, Neoplastic	12.2%
150	Rhabdomyoma	12.2%
151	Chondromatosis	12.2%
152	Adenocarcinoma, Clear Cell	12.2%
153	Cholangiocarcinoma	12.2%
154	Cervical Intraepithelial Neoplasia	12.2%
155	Hemangioblastoma	12.2%
156	Lymphoma, Extranodal NK-T-Cell	12.2%
157	Neoplasms, Experimental	11.9%
158	Neurofibrosarcoma	11.6%
159	Retinoblastoma	11.1%
160	Fibromatosis, Aggressive	10.9%
161	Fibromatosis, Abdominal	10.9%
162	Klatskin Tumor	10.9%
163	Abdominal Neoplasms	10.3%
164	Erythroplasia	10.3%
165	Follicular cyst	10.3%
166	Head and Neck Neoplasms	10.3%
167	Mucocele	10.3%
168	Pilonidal Cyst	10.3%
169	Soft Tissue Neoplasms	10.3%
170	Thoracic Neoplasms	10.3%
171	Thyroglossal Cyst	10.3%
172	Synovial Cyst	10.3%
173	Aberrant Crypt Foci	10.3%
174	Hodgkin Disease	9.8%
175	Lymphoma, Non-Hodgkin	9.8%
176	Leukemia, Myelomonocytic, Chronic	9.8%
177	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	9.8%
178	Multiple Endocrine Neoplasia	9.2%
179	Neoplasms, Radiation-Induced	8.8%
180	Lymphomatoid Granulomatosis	8.8%
181	Paraneoplastic Encephalomyelitis	8.6%
182	Hydatidiform Mole	8.5%
183	Mammary Neoplasms, Experimental	8.4%
184	Acoustic Neuroma	8.4%
185	Carcinoma, Pancreatic Ductal	8.3%
186	Mastocytoma	8.2%
187	Mastocytosis, Systemic	8.1%
188	Leukemia, Myeloid, Chronic-Phase	8.1%
189	Primary amyloidosis	7.9%
190	Hepatocellular Adenoma	7.9%
191	Basal Cell Nevus Syndrome	7.7%
192	Mastocytosis	7.6%
193	Sturge-Weber Syndrome	7.6%
194	Optic Nerve Glioma	7.5%
195	Nephroblastoma	7.5%
196	Gastrointestinal Stromal Tumors	7.4%
197	Vipoma	7.4%
198	Hemangioma, Cavernous	7.4%
199	Digestive System Neoplasms	7.3%
200	Endocrine Gland Neoplasms	7.3%
201	Eye Neoplasms	7.3%
202	Leukemia, T-Cell	7.3%
203	Nervous System Neoplasms	7.3%
204	Leukemia, B-Cell	7.3%
205	neurofibroma	7.3%
206	Lymphoma, Follicular	7.3%
207	T-Cell Lymphoma	7.3%
208	Mantle cell lymphoma	7.3%
209	Bone neoplasms	7%
210	Leukoplakia	7%
211	Lymphocele	7%
212	Pancreatic Cyst	7%
213	Skin Neoplasms	7%
214	Hematologic Neoplasms	7%
215	Barrett Esophagus	6.8%
216	Breast Cyst	6.8%
217	Actinic keratosis	6.8%
218	Mediastinal Cyst	6.8%
219	Neoplasm Invasiveness	6.8%
220	Neoplasm Metastasis	6.8%
221	Neoplasm Recurrence, Local	6.8%
222	Parovarian Cyst	6.8%
223	Pericardial Cyst	6.8%
224	Splenic Neoplasms	6.8%
225	Thymic Cyst	6.8%
226	Carcinogenesis	6.8%
227	Myxoid cyst	6.8%
228	Metastasis	6.8%
229	Mesoblastic Nephroma	6.7%
230	Retroperitoneal Neoplasms	6.7%
231	Prolactinoma	6.5%
232	Growth Hormone-Secreting Pituitary Adenoma	6.5%
233	Tuberous Sclerosis	6.1%
234	Multiple Endocrine Neoplasia Type 1	6%
235	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	6%
236	Leukemia, Large Granular Lymphocytic	6%
237	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	6%
238	Lymphoma, T-Cell, Cutaneous	6%
239	Lymphoma, AIDS-Related	6%
240	Enteropathy-Associated T-Cell Lymphoma	6%
241	Primary Effusion Lymphoma	6%
242	insulinoma	5.7%
243	Waldenstrom Macroglobulinemia	5.7%
244	Multiple Myeloma	5.7%
245	Dupuytren Contracture	5.6%
246	granulosa cell tumor	5.5%
247	Carcinoma, Ovarian Epithelial	5.5%
248	Urticaria Pigmentosa	5.5%
249	Parathyroid Neoplasms	5.5%
250	Peritoneal Neoplasms	5.5%
251	Thyroid Neoplasm	5.5%
252	Thyroid carcinoma	5.5%
253	Gastrinoma	5.4%
254	Glucagonoma	5.4%
255	Mycosis Fungoides	5.4%
256	Lymphomatoid Papulosis	5.4%
257	Plasmablastic lymphoma	5.4%
258	Adrenocortical carcinoma	5.4%
259	Adenomatous Polyposis Coli	5.1%
260	Corpus Luteum Cyst	5%
261	Ovarian Cysts	5%
262	Liver Neoplasms, Experimental	5%
263	Leydig Cell Tumor	4.9%
264	Tracheal Neoplasms	4.8%
265	Leukoplakia, Oral	4.6%
266	Paraneoplastic Cerebellar Degeneration	4.6%
267	Pancreatic Neoplasm	4.6%
268	Renal Cell Carcinoma	4.6%
269	Papillary Renal Cell Carcinoma	4.6%
270	Mouth Neoplasms	4.5%
271	Central Nervous System Neoplasms	4.5%
272	Vascular Neoplasms	4.5%
273	Thymus Neoplasms	4.5%
274	Nasopharyngeal carcinoma	4.5%
275	Carcinoma, Endometrioid	4.4%
276	Genital Neoplasms, Female	4.4%
277	Pancreatic Pseudocyst	4.4%
278	Lymphatic Metastasis	4.4%
279	Neoplasms, Unknown Primary	4.4%
280	Leukemic Infiltration	4.4%
281	Breast Neoplasms, Male	4.4%
282	Neoplasm Micrometastasis	4.4%
283	Triple Negative Breast Neoplasms	4.4%
284	Choledochal Cyst	4.1%
285	Burkitt Lymphoma	4%
286	Peutz-Jeghers Syndrome	4%
287	Thyroid Nodule	3.9%
288	Esophageal Neoplasms	3.9%
289	Limbic Encephalitis	3.8%
290	Denys-Drash Syndrome	3.8%
291	Sezary Syndrome	3.6%
292	Adrenal Gland Neoplasms	3.4%
293	Gastrointestinal Neoplasms	3.4%
294	Genital Neoplasms, Male	3.4%
295	Liver neoplasms	3.4%
296	Uveal Neoplasms	3.4%
297	Urologic Neoplasms	3.4%
298	Lambert-Eaton Myasthenic Syndrome	3.3%
299	Testicular Neoplasms	3.3%
300	Sebaceous Gland Neoplasms	3.3%
301	Spinal Neoplasms	3.3%
302	Bone Marrow Neoplasms	3.3%
303	Meningeal Neoplasms	3.3%
304	Polycystic Ovary Syndrome	3.3%
305	Opsoclonus-Myoclonus Syndrome	2.9%
306	Meningeal Carcinomatosis	2.7%
307	Palatal Neoplasms	2.6%
308	Ear Neoplasms	2.6%
309	Eyelid Neoplasms	2.6%
310	Lung Neoplasms	2.6%
311	Pleural Neoplasms	2.6%
312	Myelitis, Transverse	2.6%
313	Nose Neoplasms	2.6%
314	Cell Transformation, Viral	2.5%
315	Brain Neoplasms	2.5%
316	Salivary Gland Neoplasms	2.5%
317	Spinal Cord Neoplasms	2.5%
318	Tongue Neoplasms	2.5%
319	Uterine Neoplasms	2.4%
320	Vaginal Neoplasms	2.4%
321	Vulvar Neoplasms	2.4%
322	Uterine Cancer	2.4%
323	Fallopian Tube Neoplasms	2.4%
324	Xeroderma Pigmentosum	2.2%
325	Pituitary Adenoma	2.2%
326	Pituitary Neoplasms	2.2%
327	ovarian neoplasm	2.2%
328	Bronchial Neoplasms	2.1%
329	Pharyngeal Neoplasms	2.1%
330	Multiple Pulmonary Nodules	2.1%
331	Supratentorial Neoplasms	2%
332	Central Nervous System Cysts	2%
333	Endometrial Neoplasms	2%
334	Bile Duct Neoplasms	2%
335	gallbladder neoplasm	2%
336	Intestinal Neoplasms	2%
337	Penile Neoplasms	2%
338	Prostatic Neoplasms	2%
339	Stomach Neoplasms	2%
340	Polycythemia Vera	1.9%
341	Brain Stem Neoplasms	1.8%
342	Laryngeal neoplasm	1.7%
343	Choroid Plexus Papilloma	1.7%
344	Hypopharyngeal Neoplasms	1.7%
345	Pleural Effusion, Malignant	1.7%
346	Hypopharyngeal Cancer	1.7%
347	Zollinger-Ellison syndrome	1.6%
348	Bladder Neoplasm	1.6%
349	Kidney Neoplasm	1.6%
350	Ureteral Neoplasms	1.6%
351	Urethral Neoplasms	1.6%
352	Parotid Neoplasms	1.6%
353	Prostatic Neoplasms, Castration-Resistant	1.6%
354	Nelson Syndrome	1.6%
355	Tonsillar Neoplasms	1.5%
356	Cerebellar Neoplasms	1.4%
357	Cecal Neoplasms	1.3%
358	Duodenal Neoplasms	1.3%
359	Radicular Cyst	1.2%
360	Appendiceal Neoplasms	1.2%
361	Colonic Neoplasms	1.2%
362	Rectal Neoplasms	1.2%
363	Nasopharyngeal Neoplasms	1.2%
364	Colorectal Neoplasms	1.2%
365	Paranasal Sinus Neoplasms	1%
366	Anus Neoplasms	1%
367	Sigmoid Neoplasms	1%
368	Maxillary Sinus Neoplasms	0.9%

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