MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Neoplasm Recurrence, Local

(UMLS:C0027643)

Definition:: The local recurrence of a neoplasm following treatment. It arises from microscopic cells of the original neoplasm that have escaped therapeutic intervention and later become clinically visible at the original site.
UMLS ID:: C0027643
MeSH ID:: D009364

Classification 1:

Name:

Neoplasms
MeSH Tree Number(s):: C04.697.655

Classification 2:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.550.727.655

Synonym(s)

Neoplasm Recurrence, Local

Associated Drug(s)

	Name	Reference(s)	Data Source
1	4-aminobenzamidine	16430655	CTD
2	Anastrozole	19410462	CTD
3	Methotrexate	6230463	CTD
4	Methylprednisolone	24158386	CTD
5	Paclitaxel	11706781 18455578	CTD
6	Tamoxifen	19410462	CTD
7	Tretinoin	15982179 26285909	CTD
8	belotecan	24102892	CTD
9	gemcitabine	24158386	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Neoplasm Invasiveness	44.8%
2	Neoplasm Metastasis	44.8%
3	Carcinogenesis	44.8%
4	Metastasis	44.8%
5	Lymphatic Metastasis	32.8%
6	Neoplasms, Unknown Primary	32.8%
7	Leukemic Infiltration	32.8%
8	Neoplasm Micrometastasis	32.8%
9	Cell Transformation, Viral	21.9%
10	Polydipsia	21.1%
11	Ascites	20.9%
12	Fibrosis	20.9%
13	Gliosis	20.9%
14	Growth Disorders	20.9%
15	Hemorrhage	20.9%
16	Hyperbilirubinemia	20.9%
17	Hyperplasia	20.9%
18	Hypomenorrhea	20.9%
19	Inflammation	20.9%
20	Intraoperative Complications	20.9%
21	Ischemia	20.9%
22	Lithiasis	20.9%
23	Malacoplakia	20.9%
24	Menstruation Disturbances	20.9%
25	Metaplasia	20.9%
26	Nerve Degeneration	20.9%
27	Ochronosis	20.9%
28	Polymenorrhea	20.9%
29	Postoperative Complications	20.9%
30	Sclerosis	20.9%
31	Shock	20.9%
32	Ulcer	20.9%
33	Hyperammonemia	20.9%
34	Hyperamylasemia	20.9%
35	Teratogenesis	20.9%
36	Cardiac Death	20.9%
37	Hypovolemia	20.9%
38	Hyperuricemia	20.9%
39	Leukoaraiosis	20.9%
40	Dysbacteriosis	20.9%
41	Delayed Graft Function	20.9%
42	Cirrhosis	20.9%
43	Neointima	20.9%
44	Dysbiosis	20.9%
45	Infarction	20.3%
46	Postoperative Hemorrhage	20.3%
47	Shock, Hemorrhagic	20.3%
48	Systemic Inflammatory Response Syndrome	20.3%
49	Vascular Remodeling	16.9%
50	Cyst	16.4%
51	Extravasation of Diagnostic and Therapeutic Materials	16.4%
52	Necrosis	15.8%
53	Granulomatosis, Orofacial	15.8%
54	Pigmentation Disorders	15.8%
55	Respiratory Aspiration	15.8%
56	Acantholysis	15.5%
57	Chromosome Aberrations	15.5%
58	Dehydration	15.5%
59	Granuloma	15.5%
60	Leukocytosis	15.5%
61	Pleocytosis	15.5%
62	Sudden infant death syndrome	15%
63	Hamartoma	14.6%
64	Neoplasms, Hormone-Dependent	14.6%
65	Neoplasms, Multiple Primary	14.6%
66	Paraneoplastic Syndromes	14.6%
67	Precancerous Conditions	14.6%
68	Neoplasms, Second Primary	14.6%
69	Menorrhagia	14%
70	Acute Disease	13.6%
71	Acute-Phase Reaction	13.6%
72	Amenorrhea	13.6%
73	Chronic disease	13.6%
74	Critical Illness	13.6%
75	Sudden death	13.6%
76	Fat necrosis	13.6%
77	Gangrene	13.6%
78	Graft Occlusion, Vascular	13.6%
79	Granuloma, Plasma Cell	13.6%
80	Hematoma	13.6%
81	Iatrogenic Disease	13.6%
82	Multiple Organ Failure	13.6%
83	Oligomenorrhea	13.6%
84	Premenstrual syndrome	13.6%
85	Recurrence	13.6%
86	Retrograde Degeneration	13.6%
87	Retroperitoneal fibrosis	13.6%
88	Serositis	13.6%
89	Subcutaneous Emphysema	13.6%
90	Surgical Wound Dehiscence	13.6%
91	Syndrome	13.6%
92	Wallerian Degeneration	13.6%
93	Pyogenic granuloma	13.6%
94	Exsanguination	13.6%
95	Disease Progression	13.6%
96	Seroma	13.6%
97	Premenstrual Tension	13.6%
98	Delayed Emergence from Anesthesia	13.6%
99	Infant Death	13.6%
100	Anastomotic Leak	13.6%
101	Intraoperative Awareness	13.6%
102	Incisional hernia	13.6%
103	Chromosomal Instability	13.6%
104	jaundice	13.6%
105	Genomic Instability	12.9%
106	Pain, Postoperative	12.6%
107	Leukoplakia	12.3%
108	Signs and Symptoms	12.2%
109	Pathological Conditions, Anatomical	12.2%
110	Dysmenorrhea	12.1%
111	Failed Back Surgery Syndrome	12.1%
112	Azotemia	12.1%
113	Muscle Weakness	12%
114	Postoperative Nausea and Vomiting	12%
115	Carcinoma 256, Walker	11.8%
116	Eye Hemorrhage	11.3%
117	Carcinoma, Ehrlich Tumor	11.1%
118	Dermoid Cyst	11.1%
119	Carcinoma, Lewis Lung	11.1%
120	Endotoxic shock	11%
121	Septic Shock	11%
122	Toxic Shock Syndrome	11%
123	Hemoptysis	11%
124	Neoplastic Syndromes, Hereditary	10.9%
125	Pregnancy Complications, Neoplastic	10.9%
126	Multiple Endocrine Neoplasia	10.9%
127	Ecchymosis	10.8%
128	Petechiae	10.8%
129	Purpura	10.8%
130	Asphyxia	10.7%
131	Granuloma, Respiratory Tract	10.7%
132	Neoplasms, Experimental	10.7%
133	Shock, Traumatic	10.7%
134	Neoplasms, Neuroepithelial	10.7%
135	Gliomatosis cerebri	10.7%
136	Medulloblastoma	10.5%
137	Cardiotoxicity	10.4%
138	Disease susceptibility	10.3%
139	Fetal Death	10.3%
140	Foreign-Body Reaction	10.3%
141	Gastrointestinal Hemorrhage	10.3%
142	Hemarthrosis	10.3%
143	Hemoperitoneum	10.3%
144	Hemothorax	10.3%
145	Parovarian Cyst	10.3%
146	Postpericardiotomy Syndrome	10.3%
147	Prosthesis Failure	10.3%
148	Reperfusion Injury	10.3%
149	Injection Site Reaction	10.3%
150	Retrobulbar Hemorrhage	10.3%
151	Aseptic Necrosis of Bone	10.3%
152	Peritoneal Fibrosis	10.3%
153	Neurogenic Inflammation	10.3%
154	Perinatal death	10.3%
155	Infusion site reaction	10.3%
156	Nephrogenic Fibrosing Dermopathy	10.3%
157	Corneal Endothelial Cell Loss	10.3%
158	Encapsulating Peritoneal Sclerosis	10.3%
159	Vasoplegia	10.3%
160	Suppuration	10.3%
161	Nephrogenic Systemic Fibrosis	10.3%
162	Sinus Arrhythmia	10.2%
163	Atrial Fibrillation	10.2%
164	Atrial Flutter	10.2%
165	Dental Pulp Necrosis	10.2%
166	Granuloma, Foreign-Body	10.2%
167	Mediastinal Emphysema	10.2%
168	Surgical Wound Infection	10.2%
169	Ventricular Fibrillation	10.2%
170	Ventricular Flutter	10.2%
171	Parasystole	10.2%
172	Neuroectodermal Tumors	10.2%
173	Paroxysmal atrial fibrillation	10.2%
174	Facies	10.2%
175	Bradycardia	10.2%
176	Embryo Loss	10.2%
177	Melanoma, Experimental	10.2%
178	Tissue Adhesions	10.1%
179	Hematoma, Epidural, Spinal	10.1%
180	Afferent Loop Syndrome	10.1%
181	Sex Chromosome Aberrations	10.1%
182	Short Bowel Syndrome	10.1%
183	Uterine hemorrhage	10.1%
184	No-Reflow Phenomenon	10.1%
185	Jaundice, Obstructive	10%
186	melanoma	9.9%
187	Chromosome Fragility	9.9%
188	Paraneoplastic Encephalomyelitis	9.7%
189	Trophoblastic Neoplasms	9.6%
190	Leukemia, Experimental	9.5%
191	Mammary Neoplasms, Experimental	9.5%
192	Abdominal Neoplasms	9.3%
193	Erythroplasia	9.3%
194	Follicular cyst	9.3%
195	Head and Neck Neoplasms	9.3%
196	leukemia	9.3%
197	Mucocele	9.3%
198	Neoplasms, Germ Cell and Embryonal	9.3%
199	Neoplasms, Glandular and Epithelial	9.3%
200	Pilonidal Cyst	9.3%
201	Soft Tissue Neoplasms	9.3%
202	Thoracic Neoplasms	9.3%
203	Thyroglossal Cyst	9.3%
204	Synovial Cyst	9.3%
205	Germ Cell Cancer	9.3%
206	Aberrant Crypt Foci	9.3%
207	Carcinosarcoma	9.2%
208	Hemangiosarcoma	9.2%
209	Leukemia L1210	9.2%
210	Leukemia P388	9.2%
211	lymphangiosarcoma	9.2%
212	Acanthoma	9.2%
213	Adenoma, Acidophil	9.2%
214	Ganglioneuroma	9.2%
215	Glioma	9.2%
216	Malignant Glioma	9.2%
217	Epistaxis	9.2%
218	Meningioma	9.1%
219	Carcinoid Tumor	8.9%
220	Neurilemmoma	8.9%
221	Hutchinson's Melanotic Freckle	8.9%
222	Melanoma, Amelanotic	8.9%
223	Sarcoma 180	8.8%
224	Sarcoma, Experimental	8.8%
225	Choriocarcinoma	8.5%
226	Carcinoma, Lobular	8.5%
227	Neoplasms, Radiation-Induced	8.5%
228	Astrocytoma	8.5%
229	Ependymoma	8.5%
230	oligodendroglioma	8.5%
231	Ganglioglioma	8.5%
232	gliosarcoma	8.5%
233	Anaplastic astrocytoma	8.5%
234	Anaplastic Oligodendroglioma	8.5%
235	Drowning	8.5%
236	Sick Sinus Syndrome	8.5%
237	Trisomy	8.5%
238	Leukoplakia, Oral	8.4%
239	Hematoma, Subdural, Spinal	8.4%
240	Basal cell carcinoma	8.3%
241	Carcinoma, Papillary	8.3%
242	Squamous cell carcinoma	8.3%
243	Chondrosarcoma	8.3%
244	Craniopharyngioma	8.3%
245	Cystadenoma	8.3%
246	leiomyosarcoma	8.3%
247	liposarcoma	8.3%
248	Mesothelioma	8.3%
249	synovial sarcoma	8.3%
250	Neuroectodermal Tumor, Melanotic	8.3%
251	Angiomyolipoma	8.3%
252	Clear Cell Sarcoma of Soft Tissue	8.3%
253	Alveolar Soft Part Sarcoma	8.3%
254	Neuroendocrine Tumors	8.3%
255	Sarcoma, Myeloid	8.3%
256	Carcinoma, Basal Cell	8.3%
257	Malignant Carcinoid Syndrome	8.3%
258	Fetal Growth Retardation	8.2%
259	DNA Degradation, Necrotic	8.2%
260	Aneuploidy	8.2%
261	Polyploidy	8.2%
262	Microsatellite Instability	8.2%
263	Glioblastoma	8.1%
264	Neuroblastoma	8.1%
265	Glioblastoma Multiforme	8.1%
266	Heart Block	8.1%
267	Tachycardia	8.1%
268	Tachyarrhythmia	8.1%
269	Cicatrix	8.1%
270	Multiple Endocrine Neoplasia Type 1	8.1%
271	Hematuria	8.1%
272	Granuloma Annulare	8.1%
273	Chromosome Breakage	8.1%
274	Brain Death	8%
275	Hematemesis	8%
276	Leukemia, Radiation-Induced	8%
277	Shock, Cardiogenic	8%
278	Ganglioneuroblastoma	8%
279	Purpura Fulminans	7.9%
280	Cystadenocarcinoma	7.9%
281	Fibrosarcoma	7.9%
282	Osteosarcoma	7.9%
283	Mucoepidermoid Carcinoma	7.9%
284	Cross Infection	7.7%
285	Hyphema	7.7%
286	Retinal Neovascularization	7.7%
287	Septicemia	7.7%
288	Vitreous Hemorrhage	7.7%
289	Sepsis	7.7%
290	Adenofibroma	7.7%
291	Fibroadenoma	7.7%
292	Malignant Fibrous Histiocytoma	7.7%
293	Abscess	7.6%
294	Empyema	7.6%
295	Femur Head Necrosis	7.6%
296	Fetal Resorption	7.6%
297	Peptic Ulcer Hemorrhage	7.6%
298	Sudden Cardiac Death	7.6%
299	Premenstrual Dysphoric Disorder	7.6%
300	Choroidal Neovascularization	7.6%
301	Primary Graft Dysfunction	7.6%
302	Dumping Syndrome	7.5%
303	Cicatrix, Hypertrophic	7.5%
304	Sinus Arrest, Cardiac	7.5%
305	Metrorrhagia	7.5%
306	Tuberous Sclerosis	7.4%
307	Bowen's Disease	7.4%
308	Paraganglioma	7.4%
309	Rhabdomyosarcoma	7.4%
310	Giant Cell Tumor of Bone	7.4%
311	Thymoma	7.4%
312	Hematoma, Subdural	7.3%
313	Hematoma, Epidural, Cranial	7.3%
314	Leukemia, Plasma Cell	7.3%
315	Digestive System Neoplasms	7.3%
316	Endocrine Gland Neoplasms	7.3%
317	Eye Neoplasms	7.3%
318	Nervous System Neoplasms	7.3%
319	Dermatofibrosarcoma	7.2%
320	Dermatofibrosarcoma Protuberans	7.2%
321	Bone neoplasms	7%
322	Lymphocele	7%
323	Pancreatic Cyst	7%
324	Skin Neoplasms	7%
325	Hematologic Neoplasms	7%
326	Retinoblastoma	7%
327	Pheochromocytoma	7%
328	Alveolar rhabdomyosarcoma	7%
329	Asthenia	7%
330	Body Temperature Changes	7%
331	Calculi	7%
332	Cyanosis	7%
333	Edema	7%
334	Failure to Thrive	7%
335	Fatigue	7%
336	Feminization	7%
337	Fetal Distress	7%
338	Hernia	7%
339	Hypertrophy	7%
340	Motion Sickness	7%
341	Nails, Malformed	7%
342	polyps	7%
343	Rupture, Spontaneous	7%
344	Signs and Symptoms, Digestive	7%
345	Signs and Symptoms, Respiratory	7%
346	Skin Manifestations	7%
347	Chills	7%
348	Lassitude	7%
349	Enterocele	7%
350	Atheroma	7%
351	Pseudophakia	7%
352	Urological Manifestations	7%
353	Stenosis	7%
354	Facial asymmetry	7%
355	Mobility Limitation	7%
356	Somnolence	7%
357	Plaque, Amyloid	7%
358	Plaque, Atherosclerotic	7%
359	Lymphomatoid Granulomatosis	6.9%
360	Barrett Esophagus	6.9%
361	Breast Cyst	6.9%
362	Histiocytic Disorders, Malignant	6.9%
363	Actinic keratosis	6.9%
364	Mediastinal Cyst	6.9%
365	Parathyroid Neoplasms	6.9%
366	Pericardial Cyst	6.9%
367	Peritoneal Neoplasms	6.9%
368	Splenic Neoplasms	6.9%
369	Thymic Cyst	6.9%
370	Thyroid Neoplasm	6.9%
371	Thyroid carcinoma	6.9%
372	Myxoid cyst	6.9%
373	Carcinoma, Pancreatic Ductal	6.9%
374	Giant Cell Epulis	6.9%
375	Adenoma	6.8%
376	Ameloblastoma	6.8%
377	Angiokeratoma	6.8%
378	Carcinoma	6.8%
379	Chordoma	6.8%
380	Hemangioma	6.8%
381	hemangiopericytoma	6.8%
382	Lymphangioma	6.8%
383	Mesenchymoma	6.8%
384	Nevus	6.8%
385	Retroperitoneal Neoplasms	6.8%
386	Teratoma	6.8%
387	Hepatoblastoma	6.8%
388	Mixed Tumor, Mullerian	6.8%
389	Germinoma	6.8%
390	Teratocarcinoma	6.8%
391	Angiofibroma	6.8%
392	Sarcoma	6.8%
393	Epithelioma	6.8%
394	Carcinoid Heart Disease	6.8%
395	Long QT Syndrome	6.7%
396	Composite Lymphoma	6.7%
397	Acoustic Neuroma	6.6%
398	Viremia	6.6%
399	Parasitemia	6.6%
400	Micronuclei, Chromosome-Defective	6.6%
401	Phantom pain	6.6%
402	Phantom Limb Pain	6.6%
403	Basal Cell Nevus Syndrome	6.5%
404	Vipoma	6.3%
405	Tracheal Neoplasms	6.3%
406	Hydatidiform Mole	6.2%
407	Liver Neoplasms, Experimental	6.2%
408	Retinal Hemorrhage	6.2%
409	Neurofibrosarcoma	6.1%
410	Choroid Hemorrhage	6.1%
411	Melena	6.1%
412	Nephroblastoma	6.1%
413	Paraneoplastic Cerebellar Degeneration	6.1%
414	Hematoma, Subdural, Intracranial	6.1%
415	Hematoma, Subdural, Chronic	6.1%
416	Hematoma, Subdural, Acute	6.1%
417	Postpartum Hemorrhage	6%
418	Gingival Hemorrhage	6%
419	Keloid	6%
420	Monosomy	6%
421	Tetraploidy	6%
422	Stillbirth	6%
423	Adams-Stokes Syndrome	6%
424	Atrioventricular Block	6%
425	Bundle-Branch Block	6%
426	Atrial Premature Complexes	6%
427	Sinoatrial Block	6%
428	Tachycardia, Paroxysmal	6%
429	Supraventricular tachycardia	6%
430	Tachycardia, Ventricular	6%
431	Tachycardia, Reciprocating	6%
432	Pancreatic Neoplasm	5.9%
433	Subarachnoid Hemorrhage	5.9%
434	Cerebral Hemorrhage	5.9%
435	Abdominal Pain	5.9%
436	Optic Nerve Glioma	5.9%
437	Subacute Combined Degeneration	5.8%
438	Thrombocytopenic purpura	5.8%
439	Eosinophilic Granuloma	5.7%
440	Endometrial Stromal Sarcoma	5.7%
441	Purpura, Hyperglobulinemic	5.7%
442	Adenocarcinoma	5.6%
443	Carcinoma in Situ	5.6%
444	Carcinoma, Transitional Cell	5.6%
445	Phyllodes Tumor	5.6%
446	Dysgerminoma	5.6%
447	Hemangioendothelioma	5.6%
448	Lipoma	5.6%
449	Myoma	5.6%
450	Myxoma	5.6%
451	Neuroma	5.6%
452	Papilloma	5.6%
453	Pseudomyxoma Peritonei	5.6%
454	Seminoma	5.6%
455	Papillomatosis	5.6%
456	Angiolipoma	5.6%
457	Myelolipoma	5.6%
458	Neoplasms, Bone Tissue	5.6%
459	Neoplasms, Fibrous Tissue	5.6%
460	Smooth Muscle Tumor	5.6%
461	Adenomatosis, Pulmonary	5.6%
462	Adenomatous Polyps	5.6%
463	Carcinoma, Large Cell	5.6%
464	Carcinoma, Small Cell	5.6%
465	Desmoplastic Small Round Cell Tumor	5.6%
466	Chondroma	5.6%
467	Enchondroma	5.6%
468	Thyroid Nodule	5.6%
469	Hepatocellular Adenoma	5.6%
470	insulinoma	5.5%
471	Lymphangioleiomyomatosis	5.5%
472	Lymphoma	5.5%
473	Eye Manifestations	5.5%
474	Neurologic Manifestations	5.5%
475	Corpus Luteum Cyst	5.4%
476	Ovarian Cysts	5.4%
477	Gastrinoma	5.4%
478	Glucagonoma	5.4%
479	Esophageal Neoplasms	5.3%
480	Cardiac Output, High	5.3%
481	Myocardial Stunning	5.3%
482	Reticulocytosis	5.3%
483	Low Cardiac Output Syndrome	5.3%
484	Airway Remodeling	5.3%
485	Limbic Encephalitis	5.2%
486	Mouth Neoplasms	5.2%
487	Central Nervous System Neoplasms	5.2%
488	Vascular Neoplasms	5.2%
489	Ventricular Remodeling	5.2%
490	Thymus Neoplasms	5.2%
491	Alopecia	5.1%
492	Intermittent Claudication	5.1%
493	Androgenetic Alopecia	5.1%
494	Bacteremia	5.1%
495	Cellulitis	5.1%
496	Genital Neoplasms, Female	5.1%
497	Pancreatic Pseudocyst	5.1%
498	Plasmacytoma	5.1%
499	Kernicterus	5.1%
500	Malignant histiocytosis	5%
501	Breast Neoplasms, Male	5%
502	Histiocytic sarcoma	5%
503	Triple Negative Breast Neoplasms	5%
504	Adenoid Cystic Carcinoma	5%
505	fibroma	5%
506	Fibromatosis	5%
507	Osteoblastoma	5%
508	Osteoma	5%
509	Rhabdomyoma	5%
510	Renal Colic	5%
511	Chondromatosis	5%
512	Adenocarcinoma, Clear Cell	5%
513	Cholangiocarcinoma	5%
514	Cervical Intraepithelial Neoplasia	5%
515	Hemangioblastoma	5%
516	Lymphoma, Extranodal NK-T-Cell	5%
517	Fungemia	5%
518	Adenomatous Polyposis Coli	5%
519	Romano-Ward Syndrome	4.9%
520	Tachycardia, Atrioventricular Nodal Reentry	4.9%
521	Tachycardia, Ectopic Atrial	4.9%
522	Tachycardia, Ectopic Junctional	4.9%
523	Sinus Tachycardia	4.9%
524	Torsades de Pointes	4.9%
525	Accelerated Idioventricular Rhythm	4.9%
526	Leydig Cell Tumor	4.8%
527	Eye pain	4.8%
528	Fibromatosis, Aggressive	4.7%
529	Fibromatosis, Abdominal	4.7%
530	Klatskin Tumor	4.7%
531	Prolactinoma	4.7%
532	Growth Hormone-Secreting Pituitary Adenoma	4.7%
533	Muscular Atrophy	4.7%
534	Purpura, Thrombotic Thrombocytopenic	4.7%
535	Lambert-Eaton Myasthenic Syndrome	4.6%
536	Testicular Neoplasms	4.6%
537	Choledochal Cyst	4.6%
538	Abdomen, Acute	4.6%
539	Anorexia	4.5%
540	Anoxia	4.5%
541	Constipation	4.5%
542	Diarrhea	4.5%
543	Dyspepsia	4.5%
544	Eructation	4.5%
545	Fever	4.5%
546	Flatulence	4.5%
547	Flushing	4.5%
548	Halitosis	4.5%
549	Heartburn	4.5%
550	Diaphragmatic Hernia	4.5%
551	Hiccough	4.5%
552	Hypercalciuria	4.5%
553	Hypercapnia	4.5%
554	Hyperphagia	4.5%
555	Intestinal Polyps	4.5%
556	Nausea	4.5%
557	Pallor	4.5%
558	Psychophysiologic Disorders	4.5%
559	Splenomegaly	4.5%
560	Vomiting	4.5%
561	Hypocapnia	4.5%
562	Dyschezia	4.5%
563	Hypoxia	4.5%
564	Hyperoxia	4.5%
565	Lower Urinary Tract Symptoms	4.5%
566	Hypoxemia	4.5%
567	Urinoma	4.5%
568	Endotoxemia	4.5%
569	Peutz-Jeghers Syndrome	4.5%
570	Granuloma, Laryngeal	4.4%
571	Myocardial Reperfusion Injury	4.3%
572	Mesoblastic Nephroma	4.3%
573	Adrenocortical carcinoma	4.2%
574	Meningeal Neoplasms	4.2%
575	Adrenal Gland Neoplasms	4.2%
576	Gastrointestinal Neoplasms	4.2%
577	Genital Neoplasms, Male	4.2%
578	Hypergammaglobulinemia	4.2%
579	Leukemia, Myelomonocytic, Chronic	4.2%
580	Liver neoplasms	4.2%
581	Uveal Neoplasms	4.2%
582	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	4.2%
583	Urologic Neoplasms	4.1%
584	Opsoclonus-Myoclonus Syndrome	4.1%
585	granulosa cell tumor	4.1%
586	Carcinoma, Ovarian Epithelial	4.1%
587	Diverticulum	4.1%
588	Sebaceous Gland Neoplasms	4.1%
589	Spinal Neoplasms	4.1%
590	Bone Marrow Neoplasms	4.1%
591	Diverticulosis	4.1%
592	Hodgkin Disease	4%
593	Lymphoma, Non-Hodgkin	4%
594	Polycystic Ovary Syndrome	4%
595	Palatal Neoplasms	3.9%
596	Nose Neoplasms	3.8%
597	Mastocytoma	3.8%
598	Meningeal Carcinomatosis	3.7%
599	Mastocytosis, Systemic	3.7%
600	Leukemia, Myeloid, Chronic-Phase	3.7%
601	Autoimmune thrombocytopenia	3.7%
602	Immune thrombocytopenic purpura	3.7%
603	Renal Cell Carcinoma	3.7%
604	Papillary Renal Cell Carcinoma	3.7%
605	Myelitis, Transverse	3.6%
606	Sarcopenia	3.6%
607	Philadelphia Chromosome	3.6%
608	Respiratory Tract Fistula	3.6%
609	Waterhouse-Friderichsen Syndrome	3.6%
610	Carcinoma, Endometrioid	3.5%
611	Denys-Drash Syndrome	3.5%
612	Apnea	3.4%
613	Cheyne-Stokes Respiration	3.4%
614	Decerebrate State	3.4%
615	Dyspnea	3.4%
616	Ear Neoplasms	3.4%
617	Eyelid Neoplasms	3.4%
618	Cardiomegaly	3.4%
619	Hemiparesis	3.4%
620	Hepatomegaly	3.4%
621	Hyperventilation	3.4%
622	Lung Neoplasms	3.4%
623	Meningism	3.4%
624	Mouth Breathing	3.4%
625	Paresis	3.4%
626	Pleural Neoplasms	3.4%
627	Pruritus	3.4%
628	Seizures	3.4%
629	Sensation Disorders	3.4%
630	Sneezing	3.4%
631	Spermatocele	3.4%
632	Erythema	3.4%
633	Oral Fistula	3.4%
634	Complex partial seizures	3.4%
635	Necrolytic Migratory Erythema	3.4%
636	Tachypnea	3.4%
637	Monoparesis	3.4%
638	Cutaneous Fistula	3.4%
639	Gait Disorders, Neurologic	3.4%
640	Neuromuscular Manifestations	3.4%
641	Cardiac Hypertrophy	3.4%
642	Mastocytosis	3.4%
643	Sturge-Weber Syndrome	3.4%
644	Edema, Cardiac	3.4%
645	Mental Fatigue	3.4%
646	Hirsutism	3.4%
647	Orthostatic intolerance	3.4%
648	Hypoventilation	3.4%
649	Back Pain	3.4%
650	Bulimia	3.4%
651	Neck Pain	3.4%
652	Chest Pain	3.4%
653	Colonic Polyps	3.4%
654	Dizziness	3.4%
655	Dysuria	3.4%
656	Facial Pain	3.4%
657	Fever of Unknown Origin	3.4%
658	Flank Pain	3.4%
659	Headache	3.4%
660	Nocturia	3.4%
661	Pain, Intractable	3.4%
662	Pelvic Pain	3.4%
663	Snoring	3.4%
664	Chronic pain	3.4%
665	Lightheadedness	3.4%
666	Pain, Referred	3.4%
667	Prostatism	3.4%
668	Throbbing Headache	3.4%
669	Labor Pain	3.4%
670	Cancer Pain	3.4%
671	Nociceptive Pain	3.4%
672	Vaginal Fistula	3.4%
673	Rectocele	3.4%
674	Brain Neoplasms	3.4%
675	Salivary Gland Neoplasms	3.4%
676	Spinal Cord Neoplasms	3.4%
677	Tongue Neoplasms	3.4%
678	Gastrointestinal Stromal Tumors	3.4%
679	Nasopharyngeal carcinoma	3.4%
680	Primary amyloidosis	3.4%
681	Pituitary Adenoma	3.3%
682	Pituitary Neoplasms	3.3%
683	Body Weight Changes	3.3%
684	Hemangioma, Cavernous	3.3%
685	Leukemia, T-Cell	3.3%
686	Uterine Neoplasms	3.3%
687	Vaginal Neoplasms	3.3%
688	Vulvar Neoplasms	3.3%
689	Uterine Cancer	3.3%
690	Leukemia, B-Cell	3.3%
691	Fallopian Tube Neoplasms	3.3%
692	neurofibroma	3.3%
693	Lymphoma, Follicular	3.3%
694	T-Cell Lymphoma	3.3%
695	Mantle cell lymphoma	3.3%
696	Candidemia	3.2%
697	Bronchial Neoplasms	3.1%
698	Basal Ganglia Hemorrhage	3%
699	Gait Ataxia	3%
700	Multiple Pulmonary Nodules	3%
701	Supratentorial Neoplasms	3%
702	Hoarseness	3%
703	Endometrial Neoplasms	3%
704	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	3%
705	Leukemia, Large Granular Lymphocytic	3%
706	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	3%
707	Lymphoma, T-Cell, Cutaneous	2.9%
708	Lymphoma, AIDS-Related	2.9%
709	Enteropathy-Associated T-Cell Lymphoma	2.9%
710	Primary Effusion Lymphoma	2.9%
711	Sleep Wake Disorders	2.9%
712	Pharyngeal Neoplasms	2.9%
713	ovarian neoplasm	2.9%
714	Dupuytren Contracture	2.9%
715	Pupil Disorders	2.9%
716	Neurobehavioral Manifestations	2.9%
717	Body Weight	2.8%
718	Central Nervous System Cysts	2.8%
719	Urticaria Pigmentosa	2.8%
720	Bile Duct Neoplasms	2.8%
721	Emaciation	2.8%
722	gallbladder neoplasm	2.8%
723	Intestinal Neoplasms	2.8%
724	Low Back Pain	2.8%
725	Penile Neoplasms	2.8%
726	Prostatic Neoplasms	2.8%
727	Stomach Neoplasms	2.8%
728	Visceral Pain	2.8%
729	Brain Stem Neoplasms	2.8%
730	Nasal Polyps	2.8%
731	Mycosis Fungoides	2.8%
732	Lymphomatoid Papulosis	2.8%
733	Plasmablastic lymphoma	2.8%
734	Polycythemia Vera	2.7%
735	Pleural Rub	2.7%
736	Rales	2.7%
737	Respiratory Sounds	2.7%
738	Rhonchi	2.7%
739	Stridor	2.7%
740	Wheezing	2.7%
741	Asterixis	2.7%
742	Ballismus	2.7%
743	Vertigo	2.7%
744	Putaminal Hemorrhage	2.7%
745	Pain	2.7%
746	Xeroderma Pigmentosum	2.7%
747	Livedo Reticularis	2.7%
748	Ache	2.7%
749	Choroid Plexus Papilloma	2.7%
750	Meningocele	2.7%
751	Oliguria	2.7%
752	Polyuria	2.7%
753	Proteinuria	2.7%
754	Urinary Calculi	2.7%
755	Encephalocele	2.7%
756	Underweight	2.6%
757	Overweight	2.6%
758	Akathisia	2.6%
759	Restlessness	2.6%
760	Psychomotor Agitation	2.6%
761	Biliary Fistula	2.6%
762	Gastric Fistula	2.6%
763	Congenital diaphragmatic hernia	2.6%
764	Morning Sickness	2.6%
765	Vesicovaginal Fistula	2.6%
766	Anosmia	2.5%
767	Ataxia	2.5%
768	Athetosis	2.5%
769	Catalepsy	2.5%
770	Dental Fistula	2.5%
771	Dystonia	2.5%
772	Hemiplegia	2.5%
773	Locked-In Syndrome	2.5%
774	Muscle Hypertonia	2.5%
775	Muscle hypotonia	2.5%
776	Myoclonus	2.5%
777	Myotonia	2.5%
778	Neuralgia	2.5%
779	Oroantral Fistula	2.5%
780	Paraplegia	2.5%
781	Pseudobulbar Palsy	2.5%
782	Quadriplegia	2.5%
783	Spasm	2.5%
784	Spastic Paraplegia	2.5%
785	Status Epilepticus	2.5%
786	Taste Disorders	2.5%
787	Tremor	2.5%
788	Monoplegia	2.5%
789	Hypokinesia	2.5%
790	Left Ventricular Hypertrophy	2.5%
791	Gastroparesis	2.5%
792	Right Ventricular Hypertrophy	2.5%
793	Paraparesis	2.5%
794	Bradykinesia	2.5%
795	Waxy flexibility	2.5%
796	Action Tremor	2.5%
797	Resting Tremor	2.5%
798	Dysosmia	2.5%
799	Quadriparesis	2.5%
800	Olfaction Disorders	2.5%
801	Myokymia	2.5%
802	Somatosensory Disorders	2.5%
803	Neuropathic pain	2.5%
804	Hyperkinesia	2.5%
805	Intention tremor	2.5%
806	Cachexia	2.5%
807	Hypopharyngeal Neoplasms	2.5%
808	Pleural Effusion, Malignant	2.5%
809	Hypopharyngeal Cancer	2.5%
810	Waldenstrom Macroglobulinemia	2.5%
811	Multiple Myeloma	2.5%
812	Rectal Prolapse	2.5%
813	Uterine Prolapse	2.5%
814	Vaginal Prolapse	2.5%
815	Laryngeal neoplasm	2.5%
816	Weight Gain	2.5%
817	Parotid Neoplasms	2.5%
818	Prostatic Neoplasms, Castration-Resistant	2.5%
819	Gait Apraxia	2.5%
820	Nelson Syndrome	2.5%
821	Bladder Neoplasm	2.4%
822	Kidney Neoplasm	2.4%
823	Ureteral Neoplasms	2.4%
824	Urethral Neoplasms	2.4%
825	Tonsillar Neoplasms	2.3%
826	Voice Disorders	2.3%
827	Voice Disturbance	2.3%
828	Cerebellar Neoplasms	2.3%
829	Gagging	2.3%
830	Zollinger-Ellison syndrome	2.2%
831	Umbilical hernia	2.1%
832	Toothache	2.1%
833	Cecal Neoplasms	2.1%
834	Duodenal Neoplasms	2.1%
835	Burkitt Lymphoma	2.1%
836	Alexia	2.1%
837	Vision Disorders	2.1%
838	Metamorphopsia	2.1%
839	Dyslexia	2.1%
840	Visual Impairment	2.1%
841	Hyperemesis Gravidarum	2.1%
842	Dysgeusia	2.1%
843	Formication	2.1%
844	Hyperalgesia	2.1%
845	Hyperesthesia	2.1%
846	Hypesthesia	2.1%
847	Language Disorders	2.1%
848	Numbness	2.1%
849	Paresthesia	2.1%
850	Paraparesis, Spastic	2.1%
851	Trismus	2.1%
852	Epilepsia Partialis Continua	2.1%
853	Hypogeusia	2.1%
854	Brown-Sequard Syndrome	2.1%
855	Lockjaw	2.1%
856	Allodynia	2.1%
857	Ageusia	2.1%
858	Bronchial Fistula	2.1%
859	Metatarsalgia	2.1%
860	Pancreatic Fistula	2.1%
861	Alice in Wonderland Syndrome	2%
862	Anisocoria	2%
863	Confusion	2%
864	Facial paralysis	2%
865	Intestinal Fistula	2%
866	Lethargy	2%
867	Memory Disorders	2%
868	Muscle Cramp	2%
869	Perceptual Disorders	2%
870	Psychomotor Disorders	2%
871	Tonic Pupil	2%
872	Anhedonia	2%
873	Disorientation	2%
874	Gastroschisis	2%
875	Enterocutaneous Fistula	2%
876	Fetal Hypoxia	2%
877	Facial Paresis	2%
878	Memory Loss	2%
879	Hemisensory Neglect	2%
880	Dysacusis	2%
881	Dyspnea, Paroxysmal	2%
882	Mastodynia	2%
883	Respiratory Paralysis	2%
884	Salivary Gland Fistula	2%
885	Chorea	2%
886	Cystocele	2%
887	Tetany	2%
888	Urinary Incontinence	2%
889	Breakthrough Pain	2%
890	Sezary Syndrome	2%
891	Radicular Cyst	2%
892	Albuminuria	2%
893	Hemoglobinuria	2%
894	Appendiceal Neoplasms	2%
895	Colonic Neoplasms	2%
896	Rectal Neoplasms	2%
897	Jet Lag Syndrome	1.9%
898	Reflex, Abnormal	1.9%
899	Hyporeflexia	1.9%
900	Hyperreflexia	1.9%
901	Nasopharyngeal Neoplasms	1.9%
902	Birth Weight	1.9%
903	Agraphia	1.9%
904	Anomia	1.9%
905	Cluttering	1.9%
906	Language Development Disorders	1.9%
907	Speech Disorders	1.9%
908	Syncope	1.9%
909	Stupor	1.9%
910	Dysgraphia	1.9%
911	Presyncope	1.9%
912	Dyslalia	1.9%
913	Colorectal Neoplasms	1.8%
914	Aphasia	1.7%
915	Articulation Disorders	1.7%
916	Echolalia	1.7%
917	Stuttering	1.7%
918	Dysphasia	1.7%
919	Consciousness Disorders	1.7%
920	Mental Retardation	1.7%
921	Depressed Level of Consciousness	1.7%
922	Mental deficiency	1.7%
923	Intellectual Disability	1.7%
924	Catatonia	1.7%
925	Musculoskeletal Pain	1.7%
926	Ophthalmoplegia	1.7%
927	External Ophthalmoplegia	1.7%
928	Dysarthria	1.7%
929	Diplopia	1.7%
930	Muscle Rigidity	1.7%
931	Muscle Spasticity	1.7%
932	Scotoma	1.7%
933	Photophobia	1.7%
934	Cogwheel Rigidity	1.7%
935	Hemifacial Spasm	1.7%
936	Amaurosis	1.7%
937	Blindness	1.7%
938	Nuchal Rigidity	1.7%
939	Aphonia	1.7%
940	Arthralgia	1.7%
941	Sleep Deprivation	1.7%
942	Polyarthralgia	1.7%
943	Dysphonia	1.7%
944	Angina Pectoris	1.7%
945	Paranasal Sinus Neoplasms	1.7%
946	Agnosia	1.7%
947	Apraxias	1.7%
948	Hallucinations	1.7%
949	Hemianopsia	1.7%
950	Hyperacusis	1.7%
951	Tinnitus	1.7%
952	Visual Agnosia	1.7%
953	Anosognosia	1.7%
954	Wernicke-Korsakoff Syndrome	1.7%
955	Phonophobia	1.7%
956	Hearing Loss	1.7%
957	Anus Neoplasms	1.7%
958	Sigmoid Neoplasms	1.7%
959	Cerebrospinal Fluid Otorrhea	1.7%
960	Cerebrospinal Fluid Rhinorrhea	1.7%
961	Cerebellar Ataxia	1.7%
962	Torticollis	1.7%
963	Sciatica	1.6%
964	Urge Incontinence	1.6%
965	Tardive Dyskinesia	1.6%
966	Obesity	1.6%
967	Maxillary Sinus Neoplasms	1.5%
968	Amaurosis Fugax	1.5%
969	Blindness, Cortical	1.5%
970	Dyscalculia	1.5%
971	Angina, Unstable	1.5%
972	Hydrops Fetalis	1.5%
973	Deafness	1.5%
974	Hearing Loss, Sudden	1.5%
975	Gerstmann Syndrome	1.5%
976	Hearing Loss, Bilateral	1.5%
977	Hearing Loss, High-Frequency	1.5%
978	Hearing Loss, Mixed Conductive-Sensorineural	1.5%
979	Prosopagnosia	1.5%
980	Apraxia, Ideomotor	1.5%
981	Persistent Vegetative State	1.5%
982	Charles Bonnet Syndrome	1.5%
983	Hearing Loss, Unilateral	1.5%
984	Complete Hearing Loss	1.5%
985	Alien Hand Syndrome	1.5%
986	Deaf Mutism	1.5%
987	Vocal Cord Paralysis	1.5%
988	Fetal Weight	1.5%
989	Urinary Bladder Fistula	1.4%
990	Mutism	1.4%
991	Selective Mutism	1.4%
992	Tinea Pedis	1.4%
993	Amblyopia	1.4%
994	Amnesia	1.4%
995	Delirium	1.4%
996	Horner Syndrome	1.4%
997	Dissociative Amnesia	1.4%
998	Color blindness	1.4%
999	Global Amnesia	1.4%
1000	Angina Pectoris, Variant	1.4%
1001	Rectal Fistula	1.4%
1002	Anal Fistula	1.4%
1003	Shoulder Pain	1.4%
1004	Alexia, Pure	1.4%
1005	Pediatric Obesity	1.4%
1006	Dyskinesia, Drug-Induced	1.3%
1007	Alcohol Withdrawal Seizures	1.2%
1008	Arteriovenous fistula	1.2%
1009	Retrograde amnesia	1.2%
1010	Amnesia, Anterograde	1.2%
1011	Akathisia, Drug-Induced	1.2%
1012	Myalgia	1.2%
1013	Kidney Calculi	1.1%
1014	Ureteral Calculi	1.1%
1015	Amnesia, Transient Global	1.1%
1016	Auditory Perceptual Disorders	1%
1017	Ophthalmoplegic Migraine	0.9%
1018	Progressive supranuclear palsy	0.9%
1019	Kearns-Sayre syndrome	0.6%

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