MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Epilepsy, Generalized

(UMLS:C0014548)

Definition:: Recurrent conditions characterized by epileptic seizures which arise diffusely and simultaneously from both hemispheres of the brain. Classification is generally based upon motor manifestations of the seizure (e.g., convulsive, nonconvulsive, akinetic, atonic, etc.) or etiology (e.g., idiopathic, cryptogenic, and symptomatic). (From Mayo Clin Proc, 1996 Apr;71(4):405-14)
UMLS ID:: C0014548
MeSH ID:: D004829

Classification:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.140.490.375

Synonym(s)

Epilepsy, Generalized

Generalised epilepsy

Generalized Epilepsy

Generalized epilepsy

Generalized epilepsy, NOS

SEIZURE DISORDER GENERALIZED

epilepsy generalized

epilepsy; generalized

epilepsy; syndrome, generalized

10.

generalized epilepsy

11.

generalized epilepsy nos

12.

generalized seizure disorder

13.

generalized; epileptic

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Carbamazepine	405624	CTD
2	Clozapine	17688010	CTD
3	Diazepam	15242047	CTD
4	Lamotrigine	11052335	CTD
5	Lorazepam	3149484	CTD
6	Naloxone	8780117	CTD
7	Phenobarbital	20001779	CTD
8	Phenytoin	405624 6682525 15242047	CTD
9	Prednisolone	17951084	CTD
10	Pregabalin	20001779	CTD
11	Propofol	7474729 11244772 15242047	CTD
12	Thiamylal	11244772 15242047	CTD
13	Trazodone	8351689	CTD
14	Valproic Acid	11052335 12057805	CTD
15	Zidovudine	17304745	CTD
16	potassium bromide	20001779	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Epilepsies, Partial	48.4%
2	Simple Partial Seizures	48.4%
3	Epilepsy, Reflex	48.4%
4	Epilepsy, Temporal Lobe	47.9%
5	Epilepsy, Rolandic	47.9%
6	Benign Rolandic Epilepsy	47.9%
7	Epilepsy, Complex Partial	36%
8	Akinetic Mutism	34.4%
9	Anoxic Encephalopathy	34.4%
10	Basal Ganglia Diseases	34.4%
11	Brain Damage, Chronic	34.4%
12	Cerebellar Diseases	34.4%
13	Encephalitis	34.4%
14	Encephalomalacia	34.4%
15	Hydrocephalus	34.4%
16	Congenital Hydrocephalus	34.4%
17	Hypothalamic Diseases	34.4%
18	Thalamic Diseases	34.4%
19	Intracranial Hypertension	34.4%
20	Leukoencephalopathy	34.4%
21	Neuroaxonal Dystrophies	34.4%
22	Headache Disorders	34.4%
23	Intracranial Hypotension	34.4%
24	Brain Edema	34.4%
25	Brain Hypoxia	34.4%
26	Aqueductal Stenosis	34.4%
27	Epilepsy, Post-Traumatic	29.7%
28	Subdural Effusion	29.3%
29	Encephalomyelitis	27%
30	Posterior Leukoencephalopathy Syndrome	26.2%
31	Posterior reversible encephalopathy syndrome	26.2%
32	Meningitis	25.4%
33	Movement Disorders	25.4%
34	Pachymeningitis	25.4%
35	Spinal Cord Diseases	25.4%
36	Parkinsonian Disorders	25%
37	Meningoencephalitis	24.8%
38	Myoclonic Epilepsy	23.9%
39	Brain Diseases, Metabolic	23.6%
40	Cerebrovascular Disorders	23.6%
41	Cerebrovascular Insufficiency	23.6%
42	Dementia	23.6%
43	Basal Ganglia Cerebrovascular Disease	22.8%
44	Cerebral Palsy	22.6%
45	Pseudotumor Cerebri	22.6%
46	Hypertensive Encephalopathy	22.6%
47	Headache Disorders, Primary	22.6%
48	Headache Disorders, Secondary	22.6%
49	Medication overuse headache	22.6%
50	Dandy-Walker Syndrome	21.9%
51	Meige Syndrome	21.5%
52	Cerebral Ventriculitis	21.5%
53	Marchiafava-Bignami Disease	21.1%
54	Multiple System Atrophy	20.7%
55	Dementia, Vascular	20.4%
56	Pneumocephalus	20.4%
57	Brain Abscess	20%
58	Juvenile Myoclonic Epilepsy	19.8%
59	Myoclonic Epilepsies, Progressive	19.8%
60	Vascular Headaches	19.8%
61	Brain Injuries	19.8%
62	Myelitis	19.8%
63	Hypoxia-Ischemia, Brain	19.7%
64	Brain Neoplasms	19.7%
65	Lewy Body Disease	19.5%
66	Leukomalacia, Periventricular	18.3%
67	Brain Death	18.1%
68	Central Nervous System Infection	18.1%
69	Ocular Motility Disorders	18%
70	Cyclophoria	18%
71	Parkinson Disease	17.7%
72	Post-Traumatic Headache	16.8%
73	Tension Headache	16.8%
74	Migraine Disorders	16.8%
75	Abdominal Migraine	16.8%
76	Status Migrainosus	16.8%
77	Cervicogenic Headache	16.8%
78	Cerebellar Neoplasms	16.6%
79	Cranial nerve diseases	16.4%
80	Demyelinating Diseases	16.4%
81	Demyelination	16.4%
82	Neuromuscular Diseases	16.4%
83	Chronobiology Disorders	16.4%
84	Pituitary Diseases	16.3%
85	Creutzfeldt-Jakob disease	16.3%
86	Neuroleptic Malignant Syndrome	15.8%
87	Myelinolysis, Central Pontine	15.8%
88	Prion Diseases	15.7%
89	Epidural Abscess	15.7%
90	Carotid Artery Diseases	15.2%
91	Brain Ischemia	15.2%
92	Cerebrovascular accident	15.2%
93	Kluver-Bucy Syndrome	15.2%
94	Vasospasm, Intracranial	15.2%
95	Intracranial Arterial Diseases	15.2%
96	Amblyopia	15.2%
97	Dystonia Musculorum Deformans	15%
98	Arachnoiditis	14.8%
99	Aseptic Meningitis	14.8%
100	Syringomyelia	14.8%
101	Essential Tremor	14.8%
102	Familial Tremor	14.8%
103	Pneumorrhachis	14.8%
104	Writer's Cramp	14.8%
105	Huntington Disease	14.5%
106	Cluster Headache	13.9%
107	Migraine with Aura	13.9%
108	Familial Hemiplegic Migraine	13.9%
109	Chronic Paroxysmal Hemicrania	13.9%
110	SUNCT Syndrome	13.9%
111	Paroxysmal Hemicrania	13.9%
112	Presenile dementia	13.9%
113	Senile dementia	13.9%
114	Striatonigral Degeneration	13.9%
115	Pituitary Apoplexy	13.7%
116	Basal Ganglia Hemorrhage	13.5%
117	Brain Infarction	13.5%
118	Stiff-Person Syndrome	12.9%
119	Brain Injuries, Diffuse	12.9%
120	Traumatic Brain Injury	12.9%
121	Cerebellar Ataxia	12.9%
122	Supratentorial Neoplasms	12.9%
123	Lafora Disease	12.8%
124	Unverricht-Lundborg Syndrome	12.8%
125	Limbic Encephalitis	12.5%
126	Spinal Muscular Atrophy	12.4%
127	Progressive Muscular Atrophy	12.4%
128	Spinal Cord Injuries	12.4%
129	Persistent Vegetative State	12.4%
130	Meningitis, Bacterial	12.3%
131	Meningitis, Fungal	12.3%
132	Progressive supranuclear palsy	12.2%
133	Leukoencephalopathy, Progressive Multifocal	12.2%
134	Amnesia, Transient Global	12.1%
135	MPTP Poisoning	12%
136	Asterixis	11.8%
137	Ballismus	11.8%
138	Shy-Drager Syndrome	11.7%
139	Empty Sella Syndrome	11.6%
140	Hyperpituitarism	11.6%
141	Hypopituitarism	11.6%
142	Hypophysitis	11.6%
143	Motor Neuron Disease	11.5%
144	Reye Syndrome	11.5%
145	Putaminal Hemorrhage	11.5%
146	Trauma, Nervous System	11.4%
147	Intracranial Embolism and Thrombosis	11.4%
148	Hepatic Encephalopathy	11.4%
149	Pituitary Adenoma	11.3%
150	Pituitary Neoplasms	11.3%
151	Cerebral Arterial Diseases	11.2%
152	Vertebrobasilar Insufficiency	11.2%
153	Basilar Artery Stenosis	11.2%
154	Vertebral Artery Stenosis	11.2%
155	Intracranial Hemorrhage, Hypertensive	11.2%
156	Transient Cerebral Ischemia	11.2%
157	Poliomyelitis	11.2%
158	Cerebral Infarction	11.1%
159	Carotid Artery Injuries	11.1%
160	Paraneoplastic Cerebellar Degeneration	11.1%
161	Brain Stem Infarctions	11.1%
162	Infarction, Middle Cerebral Artery	11.1%
163	Infarction, Anterior Cerebral Artery	11.1%
164	Infarction, Posterior Cerebral Artery	11.1%
165	Lupus Vasculitis, Central Nervous System	10.9%
166	Nervous System Neoplasms	10.8%
167	Neurologic Manifestations	10.8%
168	Neurotoxicity Syndromes	10.8%
169	Encephalomyelitis, Acute Disseminated	10.7%
170	Brain Hemorrhage, Traumatic	10.7%
171	Subacute Combined Degeneration	10.6%
172	Vasculitis, Central Nervous System	10.6%
173	Leukoencephalitis, Acute Hemorrhagic	10.5%
174	Moyamoya Disease	10.3%
175	Central Nervous System Fungal Infections	10.1%
176	Conus Medullaris Syndrome	10.1%
177	Spinal Cord Vascular Diseases	10.1%
178	Friedreich Ataxia	10%
179	Hepatolenticular Degeneration	10%
180	Lateral Medullary Syndrome	10%
181	Chronic Fatigue Syndrome	9.9%
182	Toxoplasmosis, Cerebral	9.9%
183	Amyotrophic Lateral Sclerosis	9.9%
184	Spinal Cord Neoplasms	9.8%
185	Diffuse Axonal Injury	9.6%
186	Brain Stem Neoplasms	9.5%
187	Hyperprolactinemia	9.4%
188	Ophthalmoplegic Migraine	9.4%
189	Subclavian Steal Syndrome	9.3%
190	Pick Disease of the Brain	9.3%
191	Brain Diseases, Metabolic, Inborn	9.2%
192	Canavan Disease	9.1%
193	Alexander Disease	9.1%
194	Autonomic Dysreflexia	9%
195	Complex Regional Pain Syndromes	9%
196	Miller Fisher Syndrome	8.8%
197	Mitochondrial Encephalomyopathies	8.7%
198	Carotid Stenosis	8.5%
199	Intracranial Aneurysm	8.5%
200	Dysautonomia	8.5%
201	Vagus Nerve Disorder	8.5%
202	Glossopharyngeal Neuralgia	8.5%
203	Abducens Nerve Diseases	8.5%
204	Heavy Metal Poisoning, Nervous System	8.5%
205	Neuromuscular Junction Diseases	8.5%
206	Tauopathies	8.5%
207	Trochlear Nerve Diseases	8.5%
208	Peripheral Nervous System Diseases	8.5%
209	Intracranial Arteriosclerosis	8.4%
210	Cerebral Atherosclerosis	8.4%
211	Subarachnoid Hemorrhage	8.4%
212	Cerebral Arteriosclerosis	8.4%
213	Cerebral Hemorrhage	8.4%
214	Cerebral Thrombosis	8.4%
215	Intracranial Embolism	8.4%
216	Intracranial Thrombosis	8.4%
217	Sleep Wake Disorders	8.3%
218	Polyradiculoneuropathy	8.1%
219	Polyradiculoneuritis	8.1%
220	Frontotemporal dementia	8%
221	Tuberculosis, Meningeal	8%
222	Choroid Plexus Papilloma	7.9%
223	Restless Legs Syndrome	7.9%
224	Akathisia, Drug-Induced	7.8%
225	Subarachnoid Hemorrhage, Traumatic	7.8%
226	Carotid Artery, Internal, Dissection	7.8%
227	Brain Contusion	7.7%
228	Central Nervous System Bacterial Infections	7.7%
229	Myelitis, Transverse	7.6%
230	Wernicke Encephalopathy	7.6%
231	AIDS Dementia Complex	7.6%
232	Scrapie	7.5%
233	Central Cord Syndrome	7.5%
234	Auditory Perceptual Disorders	7.4%
235	Chorea	7.3%
236	Vertebral Artery Dissection	7.3%
237	Subacute Sclerosing Panencephalitis	7.3%
238	MELAS Syndrome	7.2%
239	Acromegaly	7.1%
240	Opsoclonus-Myoclonus Syndrome	7.1%
241	Cerebral Amyloid Angiopathy	7%
242	Sinus Thrombosis, Intracranial	6.9%
243	Peripheral Nerve Injuries	6.8%
244	Meningitis, Cryptococcal	6.8%
245	Meningitis, Listeria	6.8%
246	Carotid Artery Thrombosis	6.7%
247	Meningitis, Haemophilus	6.7%
248	Meningitis, Pneumococcal	6.7%
249	Myasthenia Gravis	6.7%
250	Dyskinesia, Drug-Induced	6.7%
251	Kernicterus	6.7%
252	Progressive bulbar palsy	6.6%
253	Bulbar palsy	6.6%
254	Spinal Cord Ischemia	6.5%
255	Adrenoleukodystrophy	6.5%
256	Brain Concussion	6.4%
257	Torticollis	6.4%
258	Tuberculosis, Central Nervous System	6.4%
259	Ataxia Telangiectasia	6.3%
260	Cavernous Sinus Thrombosis	6.2%
261	Sagittal Sinus Thrombosis	6.2%
262	Myopathy	6%
263	Optic Neuropathy	6%
264	Alice in Wonderland Syndrome	5.9%
265	Facial Nerve Diseases	5.7%
266	Craniocerebral Trauma	5.7%
267	Parasomnia	5.7%
268	Dyssomnias	5.7%
269	Guillain-Barre Syndrome	5.7%
270	Causalgia	5.7%
271	Vestibulocochlear Nerve Diseases	5.6%
272	Decerebrate State	5.6%
273	Hemiparesis	5.6%
274	Hydranencephaly	5.6%
275	Meningism	5.6%
276	Neural Tube Defects	5.6%
277	Paresis	5.6%
278	Seizures	5.6%
279	Sensation Disorders	5.6%
280	Tethered Cord Syndrome	5.6%
281	Central Nervous System Neoplasms	5.6%
282	Complex partial seizures	5.6%
283	Iniencephaly	5.6%
284	Craniorachischisis	5.6%
285	Exencephaly	5.6%
286	Monoparesis	5.6%
287	Septo-Optic Dysplasia	5.6%
288	Cortical Dysplasia	5.6%
289	Neurogenic Inflammation	5.6%
290	Gait Disorders, Neurologic	5.6%
291	Neuromuscular Manifestations	5.6%
292	Malformations of Cortical Development	5.6%
293	Sleep Disorders, Circadian Rhythm	5.6%
294	Sweating, Gustatory	5.6%
295	Auriculotemporal Syndrome	5.6%
296	West Nile Fever	5.5%
297	Giant Cell Arteritis	5.5%
298	Temporal Arteritis	5.5%
299	Reflex Sympathetic Dystrophy	5.4%
300	Nocturnal Myoclonus Syndrome	5.4%
301	Botulism	5.3%
302	Central Nervous System Cysts	5.3%
303	Lambert-Eaton Myasthenic Syndrome	5.2%
304	Olfactory Nerve Injuries	5.2%
305	Tardive Dyskinesia	5.2%
306	Nelson Syndrome	5%
307	Hematoma, Subdural	4.9%
308	Hematoma, Epidural, Cranial	4.9%
309	Multiple Sclerosis	4.9%
310	Neuritis	4.9%
311	Polyneuritis	4.9%
312	Radiculitis	4.9%
313	Polyneuropathy	4.9%
314	Mononeuritis	4.9%
315	Mononeuropathies	4.9%
316	Brachial Plexus Neuropathies	4.9%
317	Radiculopathy	4.9%
318	Mononeuropathy Multiplex	4.9%
319	Nerve Root Compression	4.9%
320	Neuroaspergillosis	4.9%
321	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	4.9%
322	Galactosemias	4.8%
323	Urea Cycle Disorders, Inborn	4.8%
324	Tyrosinemias	4.8%
325	Anterior Spinal Artery Syndrome	4.8%
326	Prolactinoma	4.7%
327	Growth Hormone-Secreting Pituitary Adenoma	4.7%
328	Horner Syndrome	4.6%
329	Refsum Disease	4.6%
330	Fabry Disease	4.5%
331	Pupil Disorders	4.4%
332	Neurobehavioral Manifestations	4.4%
333	Facial Nerve Injuries	4.4%
334	Neuromyelitis Optica	4.3%
335	Brachial Plexus Neuritis	4.3%
336	Neuralgic Amyotrophy	4.3%
337	Paraneoplastic Encephalomyelitis	4.3%
338	Homocystinuria	4.3%
339	Hematoma, Subdural, Intracranial	4.2%
340	Hematoma, Subdural, Chronic	4.2%
341	Hematoma, Subdural, Acute	4.2%
342	Leigh Disease	4.2%
343	Uveomeningoencephalitic Syndrome	4.2%
344	Pseudorabies	4.2%
345	Sturge-Weber Syndrome	4.2%
346	Vertigo	4.2%
347	Alcohol-Induced Disorders, Nervous System	4.2%
348	Acrodynia	4%
349	Ophthalmoplegia	4%
350	External Ophthalmoplegia	4%
351	Neurosyphilis	3.9%
352	Jet Lag Syndrome	3.9%
353	Tarsal Tunnel Syndrome	3.7%
354	Cauda Equina Syndrome	3.7%
355	Myasthenia Gravis, Autoimmune, Experimental	3.7%
356	Toxoplasmosis, Congenital	3.7%
357	Malaria, Cerebral	3.7%
358	Neurocysticercosis	3.6%
359	Menkes Kinky Hair Syndrome	3.5%
360	Charcot-Marie-Tooth Disease	3.5%
361	Carbamoyl-Phosphate Synthase I Deficiency Disease	3.5%
362	Coma, Post-Head Injury	3.5%
363	Voice Disorders	3.4%
364	Voice Disturbance	3.4%
365	Tuberous Sclerosis	3.4%
366	Myositis	3.4%
367	Optic Atrophy	3.4%
368	Optic Neuritis	3.4%
369	Papilledema	3.4%
370	Strabismus	3.4%
371	Tolosa-Hunt Syndrome	3.4%
372	Vocal Cord Paralysis	3.4%
373	Isaacs syndrome	3.4%
374	Arsenic Poisoning	3.4%
375	Myotonic Disorders	3.4%
376	Myasthenic Syndromes, Congenital	3.4%
377	Smith-Magenis syndrome	3.4%
378	Dural Arteriovenous Fistula	3.3%
379	Diabetic Neuropathies	3.3%
380	Facial Injuries	3.3%
381	Facial Neuralgia	3.3%
382	Diabetic Amyotrophy	3.3%
383	Diabetic Autonomic Neuropathy	3.3%
384	Sleep Talking	3.3%
385	Manganese Poisoning	3.3%
386	Sleep Disorders, Intrinsic	3.3%
387	Orthostatic intolerance	3.3%
388	Myotonia Congenita	3.3%
389	Anosmia	3.3%
390	Ataxia	3.3%
391	Athetosis	3.3%
392	Catalepsy	3.3%
393	Dystonia	3.3%
394	Hemiplegia	3.3%
395	Locked-In Syndrome	3.3%
396	Meningeal Neoplasms	3.3%
397	Meningomyelocele	3.3%
398	Muscle Hypertonia	3.3%
399	Muscle hypotonia	3.3%
400	Myoclonus	3.3%
401	Myotonia	3.3%
402	Neuralgia	3.3%
403	Paraplegia	3.3%
404	Pseudobulbar Palsy	3.3%
405	Quadriplegia	3.3%
406	Spasm	3.3%
407	Spastic Paraplegia	3.3%
408	Status Epilepticus	3.3%
409	Taste Disorders	3.3%
410	Tremor	3.3%
411	Spina Bifida	3.3%
412	Monoplegia	3.3%
413	Hypokinesia	3.3%
414	Paraparesis	3.3%
415	Bradykinesia	3.3%
416	Waxy flexibility	3.3%
417	Action Tremor	3.3%
418	Resting Tremor	3.3%
419	Dysosmia	3.3%
420	Quadriparesis	3.3%
421	Mercury Poisoning, Nervous System	3.3%
422	Olfaction Disorders	3.3%
423	Myokymia	3.3%
424	Lead Poisoning, Nervous System	3.3%
425	Vestibular Neuronitis	3.3%
426	Somatosensory Disorders	3.3%
427	Neuropathic pain	3.3%
428	Hyperkinesia	3.3%
429	Intention tremor	3.3%
430	Cerebrospinal Fluid Otorrhea	3.2%
431	Cerebrospinal Fluid Rhinorrhea	3.2%
432	Neuritis, Autoimmune, Experimental	3.2%
433	Gait Ataxia	3.2%
434	Sciatic Neuropathy	3.2%
435	Ulnar Neuropathies	3.2%
436	Lesion of Sciatic Nerve	3.2%
437	Ulnar Neuritis	3.2%
438	Radial nerve compression	3.2%
439	Radial Tunnel Syndrome	3.2%
440	Peroneal Neuropathies	3.2%
441	Radial Neuropathy	3.2%
442	Median Neuropathy	3.2%
443	Sciatic Nerve Palsy	3.2%
444	Femoral Neuropathy	3.2%
445	Tibial Neuropathy	3.2%
446	Ulnar Nerve Palsy	3.2%
447	Postural Orthostatic Tachycardia Syndrome	3.2%
448	Radial nerve palsy	3.2%
449	Lyme Neuroborreliosis	3.2%
450	Multiple Sclerosis, Chronic Progressive	3.2%
451	Multiple Sclerosis, Relapsing-Remitting	3.2%
452	Zellweger Syndrome	3.1%
453	Glycogen storage disease type II	3.1%
454	Carpal Tunnel Syndrome	2.8%
455	neurofibroma	2.8%
456	Sciatica	2.8%
457	Alcohol Withdrawal Seizures	2.8%
458	Reflex, Abnormal	2.7%
459	Hyporeflexia	2.7%
460	Hyperreflexia	2.7%
461	Akathisia	2.7%
462	Restlessness	2.7%
463	Psychomotor Agitation	2.7%
464	Myotonic Dystrophy	2.7%
465	Waterhouse-Friderichsen Syndrome	2.7%
466	Hand-Arm Vibration Syndrome	2.7%
467	Vision Disorders	2.6%
468	Metamorphopsia	2.6%
469	Visual Impairment	2.6%
470	Fibromyalgia	2.6%
471	Optic Neuropathy, Ischemic	2.6%
472	Anterior Ischemic Optic Neuropathy	2.6%
473	Medial Tibial Stress Syndrome	2.6%
474	Facial Hemiatrophy	2.5%
475	Melkersson-Rosenthal Syndrome	2.5%
476	Mitochondrial Myopathies	2.5%
477	Anisocoria	2.5%
478	Confusion	2.5%
479	Facial paralysis	2.5%
480	Lethargy	2.5%
481	Memory Disorders	2.5%
482	Muscle Cramp	2.5%
483	Perceptual Disorders	2.5%
484	Psychomotor Disorders	2.5%
485	Tonic Pupil	2.5%
486	Eosinophilia-Myalgia Syndrome	2.5%
487	Anhedonia	2.5%
488	Disorientation	2.5%
489	Facial Paresis	2.5%
490	Memory Loss	2.5%
491	Hemisensory Neglect	2.5%
492	Dysacusis	2.5%
493	Gaucher Disease	2.5%
494	Sleep Bruxism	2.5%
495	Anencephaly	2.5%
496	Meningocele	2.5%
497	Muscular Atrophy	2.5%
498	Respiratory Paralysis	2.5%
499	Encephalocele	2.5%
500	Tetany	2.4%
501	Gait Apraxia	2.4%
502	Polyradiculopathy	2.4%
503	Cubital Tunnel Syndrome	2.4%
504	Tay-Sachs Disease	2.3%
505	Thoracic Outlet Syndrome	2.2%
506	Optic Nerve Glioma	2.2%
507	Esotropia	2.2%
508	Exotropia	2.2%
509	Hypotension, Orthostatic	2.2%
510	Sleep Apnea Syndromes	2.2%
511	Polymyositis	2.2%
512	Post-Exercise Hypotension	2.2%
513	Disorders of Excessive Somnolence	2.2%
514	Sleep Initiation and Maintenance Disorders	2.2%
515	Night Terrors	2.2%
516	Somnambulism	2.2%
517	Trigeminal Nerve Disorder	2.2%
518	Transient Insomnia	2.2%
519	Sleep Paralysis	2.2%
520	Chronic Insomnia	2.2%
521	REM Sleep Behavior Disorder	2.2%
522	Hypersomnia	2.2%
523	Dermal Sinus	2.1%
524	Dysgeusia	2.1%
525	Formication	2.1%
526	Hyperalgesia	2.1%
527	Hyperesthesia	2.1%
528	Hypesthesia	2.1%
529	Language Disorders	2.1%
530	Numbness	2.1%
531	Paresthesia	2.1%
532	Paraparesis, Spastic	2.1%
533	Spina Bifida Cystica	2.1%
534	Trismus	2.1%
535	Spina Bifida Occulta	2.1%
536	Epilepsia Partialis Continua	2.1%
537	Hypogeusia	2.1%
538	Meningeal Carcinomatosis	2.1%
539	Brown-Sequard Syndrome	2.1%
540	Lissencephaly	2.1%
541	Polymicrogyria	2.1%
542	Pachygyria	2.1%
543	Schizencephaly	2.1%
544	Lockjaw	2.1%
545	Allodynia	2.1%
546	Lead Poisoning, Nervous System, Childhood	2.1%
547	Lead Poisoning, Nervous System, Adult	2.1%
548	Periventricular Nodular Heterotopia	2.1%
549	Ageusia	2.1%
550	Niemann-Pick Disease, Type C	2.1%
551	Alstrom Syndrome	2.1%
552	Duane Retraction Syndrome	2%
553	Consciousness Disorders	2%
554	Mental Retardation	2%
555	Muscle Weakness	2%
556	Depressed Level of Consciousness	2%
557	Mental deficiency	2%
558	Intellectual Disability	2%
559	Amyloid Neuropathies, Familial	2%
560	Mobius Syndrome	2%
561	Bell Palsy	2%
562	Catatonia	2%
563	Herpes Zoster Oticus	2%
564	Familial Periodic Paralysis	2%
565	Aphonia	2%
566	Sleep Deprivation	2%
567	Dysphonia	2%
568	Acoustic Neuroma	1.9%
569	Classical Lissencephalies and Subcortical Band Heterotopias	1.9%
570	Eye Injuries	1.7%
571	Muscular Dystrophy	1.7%
572	Congenital nystagmus	1.7%
573	Orbital Myositis	1.7%
574	Diplopia	1.6%
575	Muscle Rigidity	1.6%
576	Muscle Spasticity	1.6%
577	Scotoma	1.6%
578	Photophobia	1.6%
579	Cogwheel Rigidity	1.6%
580	Hemifacial Spasm	1.6%
581	Amaurosis	1.6%
582	Blindness	1.6%
583	Nuchal Rigidity	1.6%
584	Myalgia	1.6%
585	Pyomyositis	1.6%
586	Neuronal Ceroid-Lipofuscinoses	1.6%
587	Agnosia	1.6%
588	Apraxias	1.6%
589	Hallucinations	1.6%
590	Hemianopsia	1.6%
591	Hyperacusis	1.6%
592	Tinnitus	1.6%
593	Visual Agnosia	1.6%
594	Anosognosia	1.6%
595	Wernicke-Korsakoff Syndrome	1.6%
596	Phonophobia	1.6%
597	Hearing Loss	1.6%
598	Sarcopenia	1.6%
599	Sleep Apnea, Obstructive	1.6%
600	Sleep Apnea, Central	1.6%
601	Alexia	1.6%
602	Dyslexia	1.6%
603	Narcolepsy	1.6%
604	Trigeminal Neuralgia	1.6%
605	Kleine-Levin Syndrome	1.6%
606	Agraphia	1.6%
607	Anomia	1.6%
608	Cluttering	1.6%
609	Language Development Disorders	1.6%
610	Speech Disorders	1.6%
611	Syncope	1.6%
612	Stupor	1.6%
613	Dysgraphia	1.6%
614	Presyncope	1.6%
615	Dyslalia	1.6%
616	Neurofibrosarcoma	1.5%
617	Aicardi's syndrome	1.4%
618	Hoarseness	1.4%
619	Optic Atrophy, Hereditary, Leber	1.4%
620	Cockayne Syndrome	1.4%
621	Alcohol Withdrawal Delirium	1.4%
622	Cataplexy	1.3%
623	Aphasia	1.3%
624	Articulation Disorders	1.3%
625	Echolalia	1.3%
626	Stuttering	1.3%
627	Dysphasia	1.3%
628	Amnesia	1.3%
629	Delirium	1.3%
630	Dissociative Amnesia	1.3%
631	Color blindness	1.3%
632	Global Amnesia	1.3%
633	Cri-du-Chat Syndrome	1.3%
634	Down Syndrome	1.3%
635	Trisomy 21	1.3%
636	Kearns-Sayre syndrome	1.3%
637	POEMS Syndrome	1.3%
638	Meningioma	1.3%
639	Williams Syndrome	1.3%
640	Microcephaly	1.3%
641	Macrocephaly	1.3%
642	Hypokalemic periodic paralysis	1.3%
643	Porencephaly	1.3%
644	Holoprosencephaly	1.2%
645	Eye Burns	1.2%
646	Welander Distal Myopathy	1.2%
647	Amaurosis Fugax	1.2%
648	Blindness, Cortical	1.2%
649	Dyscalculia	1.2%
650	Rett Syndrome	1.2%
651	Deafness	1.2%
652	Hearing Loss, Sudden	1.2%
653	Gerstmann Syndrome	1.2%
654	Hearing Loss, Bilateral	1.2%
655	Hearing Loss, High-Frequency	1.2%
656	Hearing Loss, Mixed Conductive-Sensorineural	1.2%
657	Prosopagnosia	1.2%
658	Apraxia, Ideomotor	1.2%
659	Charles Bonnet Syndrome	1.2%
660	Hearing Loss, Unilateral	1.2%
661	Complete Hearing Loss	1.2%
662	Alien Hand Syndrome	1.2%
663	Deaf Mutism	1.2%
664	Dysarthria	1.2%
665	Prader-Willi Syndrome	1.1%
666	Phantom pain	1.1%
667	Phantom Limb Pain	1.1%
668	Mutism	1%
669	Selective Mutism	1%
670	Dermatomyositis	1%
671	Corneal Scar	1%
672	Muscular Dystrophy, Duchenne	1%
673	Retrograde amnesia	1%
674	Amnesia, Anterograde	1%
675	Alexia, Pure	0.9%
676	Rubinstein-Taybi Syndrome	0.8%
677	Corneal Perforation	0.8%
678	Fragile X Syndrome	0.8%
679	Mucopolysaccharidosis II	0.5%

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