MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Leukoplakia

(UMLS:C0023531)

Definition:: A white patch lesion found on a MUCOUS MEMBRANE that cannot be scraped off. Leukoplakia is generally considered a precancerous condition, however its appearance may also result from a variety of HEREDITARY DISEASES.
UMLS ID:: C0023531
MeSH ID:: D007971

Classification 1:

Name:

Neoplasms
MeSH Tree Number(s):: C04.834.512

Classification 2:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.300.816

Synonym(s)

Leukoplakia

Keratotic Plaque

LEUKOPLAKIA

Leukoplakia, NOS

leucoplakia

leukokeratosis

leukoplakia

leukoplakias

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Alendronate	FAERS: 35	US FAERS
2	Dimethyl Fumarate	FAERS: 5	US FAERS
3	Nicotine	FAERS: 3	US FAERS
4	Fluticasone-Salmeterol Drug Combination	FAERS: 2	US FAERS
5	Ketamine	FAERS: 2	US FAERS
6	Zoledronic Acid	FAERS: 2	OFFSIDES US FAERS
7	Aspirin-oxycodone hydrochloride-oxycodone terephthalate combination	FAERS: 1	US FAERS
8	Atorvastatin	FAERS: 1	US FAERS
9	BMS-790052	FAERS: 1	US FAERS
10	Leuprolide	FAERS: 1	US FAERS
11	Liraglutide	FAERS: 1	US FAERS
12	Methotrexate	FAERS: 1	US FAERS
13	Ramipril	FAERS: 1	US FAERS
14	Sertraline	FAERS: 1	US FAERS
15	Sildenafil Citrate	FAERS: 1	US FAERS
16	Simvastatin	FAERS: 1	US FAERS
17	Teriparatide	FAERS: 1	US FAERS
18	Varenicline	FAERS: 1	US FAERS
19	apixaban	FAERS: 1	US FAERS
20	azelastine	FAERS: 1	US FAERS
21	entecavir	FAERS: 1	US FAERS
22	pirfenidone	FAERS: 1	US FAERS
23	Amlodipine		OFFSIDES
24	Baclofen		OFFSIDES
25	Busulfan		OFFSIDES
26	Cetirizine		OFFSIDES
27	Cilostazol		OFFSIDES
28	Cisapride		OFFSIDES
29	Clarithromycin		OFFSIDES
30	Clopidogrel		OFFSIDES
31	Clorazepate Dipotassium		OFFSIDES
32	Delavirdine		OFFSIDES
33	Diltiazem		OFFSIDES
34	Dioctyl Sulfosuccinic Acid		OFFSIDES
35	Doxepin		OFFSIDES
36	Famotidine		OFFSIDES
37	Glatiramer Acetate		OFFSIDES
38	Irbesartan		OFFSIDES
39	Ketoconazole		OFFSIDES
40	Lenalidomide		OFFSIDES
41	Meclizine		OFFSIDES
42	Meperidine		OFFSIDES
43	Mirtazapine		OFFSIDES
44	Nabumetone		OFFSIDES
45	Nitrofurantoin		OFFSIDES
46	Nystatin		OFFSIDES
47	Ofloxacin		OFFSIDES
48	Pamidronate		OFFSIDES
49	Penicillin V		OFFSIDES
50	Piperacillin, Tazobactam Drug Combination		OFFSIDES
51	Primidone		OFFSIDES
52	Pyridostigmine Bromide		OFFSIDES
53	Ribavirin		OFFSIDES
54	Tamoxifen		OFFSIDES
55	Tazobactam		OFFSIDES
56	Terbinafine		OFFSIDES
57	Testosterone		SIDER
58	Tretinoin		OFFSIDES
59	Triamcinolone Acetonide		OFFSIDES
60	Ursodeoxycholic Acid		OFFSIDES
61	alfacalcidol		OFFSIDES
62	azelastine		OFFSIDES
63	fexofenadine		OFFSIDES
64	telithromycin		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Cyst	33.3%
2	Calculi	28.6%
3	Erythroplasia	28.6%
4	Hernia	28.6%
5	Hypertrophy	28.6%
6	Nails, Malformed	28.6%
7	polyps	28.6%
8	Rupture, Spontaneous	28.6%
9	Enterocele	28.6%
10	Atheroma	28.6%
11	Stenosis	28.6%
12	Facial asymmetry	28.6%
13	Aberrant Crypt Foci	28.6%
14	Plaque, Amyloid	28.6%
15	Plaque, Atherosclerotic	28.6%
16	Vascular Remodeling	22.9%
17	Parovarian Cyst	22.8%
18	Airway Remodeling	21.4%
19	Barrett Esophagus	21.1%
20	Actinic keratosis	21.1%
21	Ventricular Remodeling	21.1%
22	Diaphragmatic Hernia	20.9%
23	Intestinal Polyps	20.9%
24	Splenomegaly	20.9%
25	Alopecia	20.9%
26	Androgenetic Alopecia	20.9%
27	Incisional hernia	20.7%
28	Neoplastic Processes	18.5%
29	Colonic Polyps	17.2%
30	Diverticulum	16.4%
31	Diverticulosis	16.4%
32	Respiratory Tract Fistula	16.4%
33	Lymphomatoid Granulomatosis	15.9%
34	Cardiomegaly	15.8%
35	Hepatomegaly	15.8%
36	Spermatocele	15.8%
37	Oral Fistula	15.8%
38	Cutaneous Fistula	15.8%
39	Cardiac Hypertrophy	15.8%
40	Muscular Atrophy	15.6%
41	Vaginal Fistula	15.4%
42	Rectocele	15.4%
43	Hamartoma	15%
44	Neoplasms, Hormone-Dependent	15%
45	Neoplasms, Multiple Primary	15%
46	Paraneoplastic Syndromes	15%
47	Signs and Symptoms	15%
48	Neoplasms, Second Primary	15%
49	Polydipsia	14.3%
50	Vesicovaginal Fistula	13.4%
51	Biliary Fistula	13%
52	Gastric Fistula	13%
53	Congenital diaphragmatic hernia	13%
54	Sarcopenia	13%
55	Dental Fistula	12.8%
56	Oroantral Fistula	12.8%
57	Left Ventricular Hypertrophy	12.8%
58	Right Ventricular Hypertrophy	12.8%
59	Rectal Prolapse	12.7%
60	Uterine Prolapse	12.7%
61	Vaginal Prolapse	12.7%
62	Nasal Polyps	12.7%
63	Neoplasm Invasiveness	12.3%
64	Neoplasm Metastasis	12.3%
65	Neoplasm Recurrence, Local	12.3%
66	Carcinogenesis	12.3%
67	Metastasis	12.3%
68	Meningocele	12.2%
69	Urinary Calculi	12.2%
70	Encephalocele	12.2%
71	Carcinoma 256, Walker	11.9%
72	Umbilical hernia	11.7%
73	Carcinoma, Ehrlich Tumor	11.3%
74	Dermoid Cyst	11.3%
75	Carcinoma, Lewis Lung	11.3%
76	Neoplastic Syndromes, Hereditary	11.1%
77	Pregnancy Complications, Neoplastic	11.1%
78	Multiple Endocrine Neoplasia	11%
79	Neoplasms, Experimental	10.9%
80	Neoplasms, Neuroepithelial	10.8%
81	Gliomatosis cerebri	10.8%
82	Postoperative Nausea and Vomiting	10.8%
83	Medulloblastoma	10.6%
84	Bronchial Fistula	10.5%
85	Pancreatic Fistula	10.5%
86	Infarction	10.3%
87	Intestinal Fistula	10.3%
88	Postoperative Hemorrhage	10.3%
89	Shock, Hemorrhagic	10.3%
90	Neuroectodermal Tumors	10.3%
91	Systemic Inflammatory Response Syndrome	10.3%
92	Gastroschisis	10.3%
93	Enterocutaneous Fistula	10.3%
94	jaundice	10.3%
95	Melanoma, Experimental	10.3%
96	Salivary Gland Fistula	10.2%
97	Cystocele	10.1%
98	melanoma	10.1%
99	Paraneoplastic Encephalomyelitis	9.9%
100	Trophoblastic Neoplasms	9.7%
101	Leukemia, Experimental	9.7%
102	Mammary Neoplasms, Experimental	9.7%
103	Abdominal Neoplasms	9.5%
104	Ascites	9.5%
105	Asthenia	9.5%
106	Body Temperature Changes	9.5%
107	Cyanosis	9.5%
108	Edema	9.5%
109	Failure to Thrive	9.5%
110	Fatigue	9.5%
111	Feminization	9.5%
112	Fetal Distress	9.5%
113	Fibrosis	9.5%
114	Follicular cyst	9.5%
115	Gliosis	9.5%
116	Growth Disorders	9.5%
117	Head and Neck Neoplasms	9.5%
118	Hemorrhage	9.5%
119	Hyperbilirubinemia	9.5%
120	Hyperplasia	9.5%
121	Hypomenorrhea	9.5%
122	Inflammation	9.5%
123	Intraoperative Complications	9.5%
124	Ischemia	9.5%
125	leukemia	9.5%
126	Lithiasis	9.5%
127	Malacoplakia	9.5%
128	Menstruation Disturbances	9.5%
129	Metaplasia	9.5%
130	Motion Sickness	9.5%
131	Mucocele	9.5%
132	Neoplasms, Germ Cell and Embryonal	9.5%
133	Neoplasms, Glandular and Epithelial	9.5%
134	Nerve Degeneration	9.5%
135	Ochronosis	9.5%
136	Pilonidal Cyst	9.5%
137	Polymenorrhea	9.5%
138	Postoperative Complications	9.5%
139	Sclerosis	9.5%
140	Shock	9.5%
141	Signs and Symptoms, Digestive	9.5%
142	Signs and Symptoms, Respiratory	9.5%
143	Skin Manifestations	9.5%
144	Soft Tissue Neoplasms	9.5%
145	Thoracic Neoplasms	9.5%
146	Thyroglossal Cyst	9.5%
147	Ulcer	9.5%
148	Chills	9.5%
149	Synovial Cyst	9.5%
150	Lassitude	9.5%
151	Hyperammonemia	9.5%
152	Hyperamylasemia	9.5%
153	Teratogenesis	9.5%
154	Cardiac Death	9.5%
155	Hypovolemia	9.5%
156	Pseudophakia	9.5%
157	Germ Cell Cancer	9.5%
158	Hyperuricemia	9.5%
159	Urological Manifestations	9.5%
160	Leukoaraiosis	9.5%
161	Dysbacteriosis	9.5%
162	Mobility Limitation	9.5%
163	Delayed Graft Function	9.5%
164	Cirrhosis	9.5%
165	Somnolence	9.5%
166	Neointima	9.5%
167	Dysbiosis	9.5%
168	Abdominal Pain	9.4%
169	Carcinosarcoma	9.4%
170	Hemangiosarcoma	9.4%
171	Leukemia L1210	9.4%
172	Leukemia P388	9.4%
173	lymphangiosarcoma	9.4%
174	Lymphatic Metastasis	9.4%
175	Neoplasms, Unknown Primary	9.4%
176	Pain, Postoperative	9.4%
177	Leukemic Infiltration	9.4%
178	Acanthoma	9.4%
179	Neoplasm Micrometastasis	9.4%
180	Adenoma, Acidophil	9.3%
181	Ganglioneuroma	9.3%
182	Glioma	9.3%
183	Malignant Glioma	9.3%
184	Meningioma	9.2%
185	Carcinoid Tumor	9%
186	Neurilemmoma	9%
187	Hutchinson's Melanotic Freckle	9%
188	Melanoma, Amelanotic	9%
189	Dysmenorrhea	8.9%
190	Sarcoma 180	8.9%
191	Failed Back Surgery Syndrome	8.9%
192	Sarcoma, Experimental	8.9%
193	Choriocarcinoma	8.6%
194	Carcinoma, Lobular	8.6%
195	Neoplasms, Radiation-Induced	8.6%
196	Astrocytoma	8.6%
197	Ependymoma	8.6%
198	oligodendroglioma	8.6%
199	Ganglioglioma	8.6%
200	gliosarcoma	8.6%
201	Anaplastic astrocytoma	8.6%
202	Anaplastic Oligodendroglioma	8.6%
203	Eye Hemorrhage	8.6%
204	Basal cell carcinoma	8.5%
205	Carcinoma, Papillary	8.5%
206	Squamous cell carcinoma	8.5%
207	Chondrosarcoma	8.5%
208	Craniopharyngioma	8.5%
209	Cystadenoma	8.5%
210	Jaundice, Obstructive	8.5%
211	leiomyosarcoma	8.5%
212	liposarcoma	8.5%
213	Mesothelioma	8.5%
214	Sudden infant death syndrome	8.5%
215	synovial sarcoma	8.5%
216	Neuroectodermal Tumor, Melanotic	8.5%
217	Angiomyolipoma	8.5%
218	Clear Cell Sarcoma of Soft Tissue	8.5%
219	Alveolar Soft Part Sarcoma	8.5%
220	Neuroendocrine Tumors	8.5%
221	Sarcoma, Myeloid	8.5%
222	Carcinoma, Basal Cell	8.5%
223	Malignant Carcinoid Syndrome	8.4%
224	Hemoptysis	8.3%
225	Glioblastoma	8.3%
226	Neuroblastoma	8.3%
227	Glioblastoma Multiforme	8.3%
228	Ecchymosis	8.2%
229	Petechiae	8.2%
230	Purpura	8.2%
231	Multiple Endocrine Neoplasia Type 1	8.2%
232	Xeroderma Pigmentosum	8.2%
233	Leukemia, Radiation-Induced	8.1%
234	Ganglioneuroblastoma	8.1%
235	Abdomen, Acute	8%
236	Cystadenocarcinoma	8%
237	Fibrosarcoma	8%
238	Osteosarcoma	8%
239	Mucoepidermoid Carcinoma	8%
240	Adenofibroma	7.8%
241	Fibroadenoma	7.8%
242	Malignant Fibrous Histiocytoma	7.8%
243	Eye pain	7.6%
244	Bowen's Disease	7.6%
245	Paraganglioma	7.6%
246	Rhabdomyosarcoma	7.6%
247	Giant Cell Tumor of Bone	7.6%
248	Rectal Fistula	7.5%
249	Anal Fistula	7.5%
250	Muscle Weakness	7.5%
251	Tuberous Sclerosis	7.5%
252	Thymoma	7.5%
253	Leukemia, Plasma Cell	7.4%
254	Digestive System Neoplasms	7.4%
255	Endocrine Gland Neoplasms	7.4%
256	Extravasation of Diagnostic and Therapeutic Materials	7.4%
257	Eye Manifestations	7.4%
258	Eye Neoplasms	7.4%
259	Menorrhagia	7.4%
260	Nervous System Neoplasms	7.4%
261	Neurologic Manifestations	7.4%
262	Renal Colic	7.3%
263	Dermatofibrosarcoma	7.3%
264	Dermatofibrosarcoma Protuberans	7.3%
265	Urinary Bladder Fistula	7.2%
266	Bone neoplasms	7.1%
267	Lymphocele	7.1%
268	Necrosis	7.1%
269	Pancreatic Cyst	7.1%
270	Skin Neoplasms	7.1%
271	Cardiac Output, High	7.1%
272	Myocardial Stunning	7.1%
273	Reticulocytosis	7.1%
274	Hematologic Neoplasms	7.1%
275	Granulomatosis, Orofacial	7.1%
276	Pigmentation Disorders	7.1%
277	Low Cardiac Output Syndrome	7.1%
278	Respiratory Aspiration	7.1%
279	Pheochromocytoma	7.1%
280	Alveolar rhabdomyosarcoma	7.1%
281	Retinoblastoma	7.1%
282	Acantholysis	7%
283	Breast Cyst	7%
284	Chromosome Aberrations	7%
285	Dehydration	7%
286	Granuloma	7%
287	Histiocytic Disorders, Malignant	7%
288	Leukocytosis	7%
289	Mediastinal Cyst	7%
290	Pericardial Cyst	7%
291	Splenic Neoplasms	7%
292	Thymic Cyst	7%
293	Pleocytosis	7%
294	Myxoid cyst	7%
295	Acute Disease	7%
296	Acute-Phase Reaction	7%
297	Adenoma	7%
298	Ameloblastoma	7%
299	Amenorrhea	7%
300	Angiokeratoma	7%
301	Anorexia	7%
302	Anoxia	7%
303	Carcinoma	7%
304	Chordoma	7%
305	Chronic disease	7%
306	Constipation	7%
307	Critical Illness	7%
308	Sudden death	7%
309	Diarrhea	7%
310	Dyspepsia	7%
311	Epistaxis	7%
312	Eructation	7%
313	Fat necrosis	7%
314	Fever	7%
315	Flatulence	7%
316	Flushing	7%
317	Gangrene	7%
318	Graft Occlusion, Vascular	7%
319	Granuloma, Plasma Cell	7%
320	Halitosis	7%
321	Heartburn	7%
322	Hemangioma	7%
323	hemangiopericytoma	7%
324	Hematoma	7%
325	Hiccough	7%
326	Hypercalciuria	7%
327	Hypercapnia	7%
328	Hyperphagia	7%
329	Iatrogenic Disease	7%
330	Lymphangioma	7%
331	Mesenchymoma	7%
332	Multiple Organ Failure	7%
333	Nausea	7%
334	Nevus	7%
335	Oligomenorrhea	7%
336	Pallor	7%
337	Parathyroid Neoplasms	7%
338	Peritoneal Neoplasms	7%
339	Premenstrual syndrome	7%
340	Psychophysiologic Disorders	7%
341	Recurrence	7%
342	Retrograde Degeneration	7%
343	Retroperitoneal fibrosis	7%
344	Retroperitoneal Neoplasms	7%
345	Serositis	7%
346	Subcutaneous Emphysema	7%
347	Surgical Wound Dehiscence	7%
348	Syndrome	7%
349	Teratoma	7%
350	Thyroid Neoplasm	7%
351	Vomiting	7%
352	Wallerian Degeneration	7%
353	Hypocapnia	7%
354	Pyogenic granuloma	7%
355	Hepatoblastoma	7%
356	Mixed Tumor, Mullerian	7%
357	Germinoma	7%
358	Teratocarcinoma	7%
359	Angiofibroma	7%
360	Exsanguination	7%
361	Dyschezia	7%
362	Hypoxia	7%
363	Disease Progression	7%
364	Hyperoxia	7%
365	Seroma	7%
366	Premenstrual Tension	7%
367	Delayed Emergence from Anesthesia	7%
368	Infant Death	7%
369	Thyroid carcinoma	7%
370	Lower Urinary Tract Symptoms	7%
371	Hypoxemia	7%
372	Anastomotic Leak	7%
373	Intraoperative Awareness	7%
374	Sarcoma	7%
375	Urinoma	7%
376	Epithelioma	7%
377	Intermittent Claudication	7%
378	Carcinoma, Pancreatic Ductal	6.9%
379	Carcinoid Heart Disease	6.9%
380	Chromosomal Instability	6.9%
381	Hematemesis	6.8%
382	Composite Lymphoma	6.7%
383	Purpura Fulminans	6.7%
384	Acoustic Neuroma	6.7%
385	Phantom pain	6.6%
386	Phantom Limb Pain	6.6%
387	Basal Cell Nevus Syndrome	6.5%
388	Cell Transformation, Viral	6.5%
389	Endotoxic shock	6.4%
390	Septic Shock	6.4%
391	Toxic Shock Syndrome	6.4%
392	Tracheal Neoplasms	6.4%
393	Vipoma	6.4%
394	Hydatidiform Mole	6.3%
395	Liver Neoplasms, Experimental	6.3%
396	Arteriovenous fistula	6.2%
397	Neurofibrosarcoma	6.2%
398	Paraneoplastic Cerebellar Degeneration	6.2%
399	Nephroblastoma	6.2%
400	Pancreatic Neoplasm	6%
401	Optic Nerve Glioma	5.9%
402	Genomic Instability	5.8%
403	Endometrial Stromal Sarcoma	5.8%
404	Adenocarcinoma	5.7%
405	Tissue Adhesions	5.7%
406	Back Pain	5.7%
407	Bulimia	5.7%
408	Carcinoma in Situ	5.7%
409	Carcinoma, Transitional Cell	5.7%
410	Neck Pain	5.7%
411	Chest Pain	5.7%
412	Phyllodes Tumor	5.7%
413	Dizziness	5.7%
414	Dysgerminoma	5.7%
415	Dysuria	5.7%
416	Facial Pain	5.7%
417	Fever of Unknown Origin	5.7%
418	Flank Pain	5.7%
419	Headache	5.7%
420	Hemangioendothelioma	5.7%
421	Lipoma	5.7%
422	Myoma	5.7%
423	Myxoma	5.7%
424	Neuroma	5.7%
425	Nocturia	5.7%
426	Pain, Intractable	5.7%
427	Papilloma	5.7%
428	Pelvic Pain	5.7%
429	Pseudomyxoma Peritonei	5.7%
430	Seminoma	5.7%
431	Snoring	5.7%
432	Chronic pain	5.7%
433	Papillomatosis	5.7%
434	Angiolipoma	5.7%
435	Myelolipoma	5.7%
436	Neoplasms, Bone Tissue	5.7%
437	Neoplasms, Fibrous Tissue	5.7%
438	Smooth Muscle Tumor	5.7%
439	Adenomatosis, Pulmonary	5.7%
440	Adenomatous Polyps	5.7%
441	Carcinoma, Large Cell	5.7%
442	Lightheadedness	5.7%
443	Pain, Referred	5.7%
444	Prostatism	5.7%
445	Carcinoma, Small Cell	5.7%
446	Desmoplastic Small Round Cell Tumor	5.7%
447	Throbbing Headache	5.7%
448	Labor Pain	5.7%
449	Cancer Pain	5.7%
450	Hematoma, Epidural, Spinal	5.7%
451	Chondroma	5.7%
452	Enchondroma	5.7%
453	Nociceptive Pain	5.7%
454	Hypergammaglobulinemia	5.6%
455	Thyroid Nodule	5.6%
456	Hepatocellular Adenoma	5.6%
457	Chromosome Fragility	5.6%
458	Lymphoma	5.6%
459	Lymphangioleiomyomatosis	5.6%
460	insulinoma	5.5%
461	Corpus Luteum Cyst	5.5%
462	Ovarian Cysts	5.5%
463	Kidney Calculi	5.5%
464	Ureteral Calculi	5.5%
465	Azotemia	5.5%
466	Asphyxia	5.5%
467	Granuloma, Respiratory Tract	5.5%
468	Shock, Traumatic	5.5%
469	Gastrinoma	5.4%
470	Glucagonoma	5.4%
471	Esophageal Neoplasms	5.3%
472	Gait Ataxia	5.3%
473	Apnea	5.3%
474	Cheyne-Stokes Respiration	5.3%
475	Decerebrate State	5.3%
476	Disease susceptibility	5.3%
477	Dyspnea	5.3%
478	Fetal Death	5.3%
479	Foreign-Body Reaction	5.3%
480	Gastrointestinal Hemorrhage	5.3%
481	Hemarthrosis	5.3%
482	Hemiparesis	5.3%
483	Hemoperitoneum	5.3%
484	Hemothorax	5.3%
485	Hyperventilation	5.3%
486	Meningism	5.3%
487	Mouth Breathing	5.3%
488	Mouth Neoplasms	5.3%
489	Paresis	5.3%
490	Postpericardiotomy Syndrome	5.3%
491	Prosthesis Failure	5.3%
492	Pruritus	5.3%
493	Reperfusion Injury	5.3%
494	Seizures	5.3%
495	Sensation Disorders	5.3%
496	Sneezing	5.3%
497	Erythema	5.3%
498	Central Nervous System Neoplasms	5.3%
499	Complex partial seizures	5.3%
500	Injection Site Reaction	5.3%
501	Necrolytic Migratory Erythema	5.3%
502	Tachypnea	5.3%
503	Monoparesis	5.3%
504	Vascular Neoplasms	5.3%
505	Retrobulbar Hemorrhage	5.3%
506	Limbic Encephalitis	5.3%
507	Aseptic Necrosis of Bone	5.3%
508	Peritoneal Fibrosis	5.3%
509	Neurogenic Inflammation	5.3%
510	Perinatal death	5.3%
511	Gait Disorders, Neurologic	5.3%
512	Neuromuscular Manifestations	5.3%
513	Infusion site reaction	5.3%
514	Nephrogenic Fibrosing Dermopathy	5.3%
515	Corneal Endothelial Cell Loss	5.3%
516	Encapsulating Peritoneal Sclerosis	5.3%
517	Vasoplegia	5.3%
518	Suppuration	5.3%
519	Thymus Neoplasms	5.3%
520	Nephrogenic Systemic Fibrosis	5.3%
521	Sinus Arrhythmia	5.2%
522	Atrial Fibrillation	5.2%
523	Atrial Flutter	5.2%
524	Dental Pulp Necrosis	5.2%
525	Edema, Cardiac	5.2%
526	Mental Fatigue	5.2%
527	Genital Neoplasms, Female	5.2%
528	Granuloma, Foreign-Body	5.2%
529	Hirsutism	5.2%
530	Mediastinal Emphysema	5.2%
531	Pancreatic Pseudocyst	5.2%
532	Plasmacytoma	5.2%
533	Surgical Wound Infection	5.2%
534	Ventricular Fibrillation	5.2%
535	Ventricular Flutter	5.2%
536	Parasystole	5.2%
537	Paroxysmal atrial fibrillation	5.2%
538	Facies	5.2%
539	Bradycardia	5.2%
540	Embryo Loss	5.2%
541	Orthostatic intolerance	5.2%
542	Hypoventilation	5.2%
543	Adenoid Cystic Carcinoma	5.1%
544	Emaciation	5.1%
545	fibroma	5.1%
546	Fibromatosis	5.1%
547	Low Back Pain	5.1%
548	Osteoblastoma	5.1%
549	Osteoma	5.1%
550	Rhabdomyoma	5.1%
551	Chondromatosis	5.1%
552	Adenocarcinoma, Clear Cell	5.1%
553	Cholangiocarcinoma	5.1%
554	Cervical Intraepithelial Neoplasia	5.1%
555	Hemangioblastoma	5.1%
556	Visceral Pain	5.1%
557	Hematoma, Subdural, Spinal	5.1%
558	Lymphoma, Extranodal NK-T-Cell	5.1%
559	Afferent Loop Syndrome	5.1%
560	Malignant histiocytosis	5.1%
561	Sex Chromosome Aberrations	5.1%
562	Short Bowel Syndrome	5.1%
563	Uterine hemorrhage	5.1%
564	No-Reflow Phenomenon	5.1%
565	Breast Neoplasms, Male	5.1%
566	Histiocytic sarcoma	5.1%
567	Triple Negative Breast Neoplasms	5.1%
568	Body Weight Changes	5.1%
569	Adenomatous Polyposis Coli	5%
570	Thrombocytopenic purpura	4.9%
571	Cachexia	4.8%
572	Fibromatosis, Aggressive	4.8%
573	Fibromatosis, Abdominal	4.8%
574	Klatskin Tumor	4.8%
575	Leydig Cell Tumor	4.8%
576	Prolactinoma	4.8%
577	Growth Hormone-Secreting Pituitary Adenoma	4.8%
578	Purpura, Hyperglobulinemic	4.8%
579	Sick Sinus Syndrome	4.7%
580	Trisomy	4.7%
581	Hoarseness	4.7%
582	Lambert-Eaton Myasthenic Syndrome	4.7%
583	Testicular Neoplasms	4.7%
584	Cardiotoxicity	4.7%
585	Choledochal Cyst	4.7%
586	Akathisia	4.5%
587	Restlessness	4.5%
588	Psychomotor Agitation	4.5%
589	Peutz-Jeghers Syndrome	4.5%
590	Sleep Wake Disorders	4.5%
591	Gait Apraxia	4.4%
592	Cross Infection	4.3%
593	Hyphema	4.3%
594	Pupil Disorders	4.3%
595	Retinal Neovascularization	4.3%
596	Septicemia	4.3%
597	Vitreous Hemorrhage	4.3%
598	Sepsis	4.3%
599	Morning Sickness	4.3%
600	Neurobehavioral Manifestations	4.3%
601	Mesoblastic Nephroma	4.3%
602	Drowning	4.3%
603	Abscess	4.3%
604	Anosmia	4.3%
605	Ataxia	4.3%
606	Athetosis	4.3%
607	Catalepsy	4.3%
608	Dystonia	4.3%
609	Empyema	4.3%
610	Femur Head Necrosis	4.3%
611	Fetal Resorption	4.3%
612	Hemiplegia	4.3%
613	Locked-In Syndrome	4.3%
614	Meningeal Neoplasms	4.3%
615	Muscle Hypertonia	4.3%
616	Muscle hypotonia	4.3%
617	Myoclonus	4.3%
618	Myotonia	4.3%
619	Neuralgia	4.3%
620	Paraplegia	4.3%
621	Peptic Ulcer Hemorrhage	4.3%
622	Pseudobulbar Palsy	4.3%
623	Quadriplegia	4.3%
624	Spasm	4.3%
625	Spastic Paraplegia	4.3%
626	Status Epilepticus	4.3%
627	Taste Disorders	4.3%
628	Tremor	4.3%
629	Sudden Cardiac Death	4.3%
630	Monoplegia	4.3%
631	Hypokinesia	4.3%
632	Gastroparesis	4.3%
633	Paraparesis	4.3%
634	Bradykinesia	4.3%
635	Waxy flexibility	4.3%
636	Action Tremor	4.3%
637	Resting Tremor	4.3%
638	Dysosmia	4.3%
639	Quadriparesis	4.3%
640	Premenstrual Dysphoric Disorder	4.3%
641	Olfaction Disorders	4.3%
642	Choroidal Neovascularization	4.3%
643	Myokymia	4.3%
644	Somatosensory Disorders	4.3%
645	Primary Graft Dysfunction	4.3%
646	Neuropathic pain	4.3%
647	Hyperkinesia	4.3%
648	Intention tremor	4.3%
649	Adrenocortical carcinoma	4.2%
650	Purpura, Thrombotic Thrombocytopenic	4.2%
651	Dumping Syndrome	4.2%
652	Leukemia, Myelomonocytic, Chronic	4.2%
653	Cicatrix, Hypertrophic	4.2%
654	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	4.2%
655	Sinus Arrest, Cardiac	4.2%
656	Adrenal Gland Neoplasms	4.2%
657	Gastrointestinal Neoplasms	4.2%
658	Genital Neoplasms, Male	4.2%
659	Liver neoplasms	4.2%
660	Uveal Neoplasms	4.2%
661	Metrorrhagia	4.2%
662	Weight Gain	4.2%
663	Fetal Growth Retardation	4.2%
664	Pleural Rub	4.2%
665	Rales	4.2%
666	Respiratory Sounds	4.2%
667	Rhonchi	4.2%
668	Stridor	4.2%
669	Urologic Neoplasms	4.2%
670	Wheezing	4.2%
671	Asterixis	4.2%
672	Ballismus	4.2%
673	DNA Degradation, Necrotic	4.2%
674	Aneuploidy	4.1%
675	Polyploidy	4.1%
676	Vertigo	4.1%
677	Microsatellite Instability	4.1%
678	Opsoclonus-Myoclonus Syndrome	4.1%
679	granulosa cell tumor	4.1%
680	Carcinoma, Ovarian Epithelial	4.1%
681	Hematoma, Subdural	4.1%
682	Hematoma, Epidural, Cranial	4.1%
683	Heart Block	4.1%
684	Pain	4.1%
685	Sebaceous Gland Neoplasms	4.1%
686	Spinal Neoplasms	4.1%
687	Tachycardia	4.1%
688	Tachyarrhythmia	4.1%
689	Livedo Reticularis	4.1%
690	Ache	4.1%
691	Bone Marrow Neoplasms	4.1%
692	Cicatrix	4.1%
693	Hematuria	4.1%
694	Oliguria	4.1%
695	Polyuria	4.1%
696	Proteinuria	4.1%
697	Granuloma Annulare	4.1%
698	Chromosome Breakage	4.1%
699	Brain Death	4.1%
700	Hodgkin Disease	4.1%
701	Lymphoma, Non-Hodgkin	4.1%
702	Shock, Cardiogenic	4.1%
703	Viremia	4%
704	Parasitemia	4%
705	Polycystic Ovary Syndrome	4%
706	Underweight	4%
707	Overweight	4%
708	Alexia	4%
709	Dyslexia	4%
710	Palatal Neoplasms	4%
711	Toothache	3.9%
712	Body Weight	3.8%
713	Nose Neoplasms	3.8%
714	Hyperemesis Gravidarum	3.8%
715	Mastocytoma	3.8%
716	Dysgeusia	3.8%
717	Formication	3.8%
718	Hyperalgesia	3.8%
719	Hyperesthesia	3.8%
720	Hypesthesia	3.8%
721	Language Disorders	3.8%
722	Numbness	3.8%
723	Paresthesia	3.8%
724	Paraparesis, Spastic	3.8%
725	Trismus	3.8%
726	Epilepsia Partialis Continua	3.8%
727	Hypogeusia	3.8%
728	Meningeal Carcinomatosis	3.8%
729	Mastocytosis, Systemic	3.8%
730	Brown-Sequard Syndrome	3.8%
731	Lockjaw	3.8%
732	Allodynia	3.8%
733	Ageusia	3.8%
734	Leukemia, Myeloid, Chronic-Phase	3.8%
735	Alice in Wonderland Syndrome	3.7%
736	Renal Cell Carcinoma	3.7%
737	Papillary Renal Cell Carcinoma	3.7%
738	Myelitis, Transverse	3.7%
739	Hematoma, Subdural, Intracranial	3.7%
740	Hematoma, Subdural, Chronic	3.7%
741	Hematoma, Subdural, Acute	3.7%
742	Carcinoma, Endometrioid	3.6%
743	Agraphia	3.6%
744	Anomia	3.6%
745	Cluttering	3.6%
746	Language Development Disorders	3.6%
747	Speech Disorders	3.6%
748	Syncope	3.6%
749	Stupor	3.6%
750	Dysgraphia	3.6%
751	Presyncope	3.6%
752	Dyslalia	3.6%
753	Vision Disorders	3.5%
754	Metamorphopsia	3.5%
755	Visual Impairment	3.5%
756	Denys-Drash Syndrome	3.5%
757	Voice Disorders	3.5%
758	Voice Disturbance	3.5%
759	Ear Neoplasms	3.5%
760	Eyelid Neoplasms	3.5%
761	Lung Neoplasms	3.5%
762	Metatarsalgia	3.5%
763	Pleural Neoplasms	3.5%
764	Retinal Hemorrhage	3.5%
765	Giant Cell Epulis	3.5%
766	Anisocoria	3.4%
767	Aphasia	3.4%
768	Articulation Disorders	3.4%
769	Choroid Hemorrhage	3.4%
770	Confusion	3.4%
771	Echolalia	3.4%
772	Facial paralysis	3.4%
773	Gagging	3.4%
774	Lethargy	3.4%
775	Mastocytosis	3.4%
776	Melena	3.4%
777	Memory Disorders	3.4%
778	Muscle Cramp	3.4%
779	Perceptual Disorders	3.4%
780	Psychomotor Disorders	3.4%
781	Sturge-Weber Syndrome	3.4%
782	Stuttering	3.4%
783	Tonic Pupil	3.4%
784	Anhedonia	3.4%
785	Disorientation	3.4%
786	Fetal Hypoxia	3.4%
787	Facial Paresis	3.4%
788	Memory Loss	3.4%
789	Hemisensory Neglect	3.4%
790	Dysphasia	3.4%
791	Dysacusis	3.4%
792	Brain Neoplasms	3.4%
793	Dyspnea, Paroxysmal	3.4%
794	Mastodynia	3.4%
795	Postpartum Hemorrhage	3.4%
796	Respiratory Paralysis	3.4%
797	Salivary Gland Neoplasms	3.4%
798	Spinal Cord Neoplasms	3.4%
799	Tongue Neoplasms	3.4%
800	Gastrointestinal Stromal Tumors	3.4%
801	Dysarthria	3.4%
802	Long QT Syndrome	3.4%
803	Primary amyloidosis	3.4%
804	Nasopharyngeal carcinoma	3.4%
805	Chorea	3.4%
806	Gingival Hemorrhage	3.4%
807	Hemangioma, Cavernous	3.4%
808	Keloid	3.4%
809	Tetany	3.4%
810	Urinary Incontinence	3.4%
811	Breakthrough Pain	3.4%
812	Pituitary Adenoma	3.4%
813	Pituitary Neoplasms	3.4%
814	Monosomy	3.4%
815	Tetraploidy	3.4%
816	Stillbirth	3.4%
817	Adams-Stokes Syndrome	3.4%
818	Atrioventricular Block	3.4%
819	Bundle-Branch Block	3.4%
820	Leukemia, T-Cell	3.4%
821	Atrial Premature Complexes	3.4%
822	Sinoatrial Block	3.4%
823	Tachycardia, Paroxysmal	3.4%
824	Supraventricular tachycardia	3.4%
825	Uterine Neoplasms	3.4%
826	Vaginal Neoplasms	3.4%
827	Tachycardia, Ventricular	3.4%
828	Vulvar Neoplasms	3.4%
829	Uterine Cancer	3.4%
830	Tachycardia, Reciprocating	3.4%
831	Leukemia, B-Cell	3.4%
832	Autoimmune thrombocytopenia	3.4%
833	Immune thrombocytopenic purpura	3.4%
834	Albuminuria	3.3%
835	Fallopian Tube Neoplasms	3.3%
836	Hemoglobinuria	3.3%
837	neurofibroma	3.3%
838	Subarachnoid Hemorrhage	3.3%
839	Cerebral Hemorrhage	3.3%
840	Micronuclei, Chromosome-Defective	3.3%
841	Lymphoma, Follicular	3.3%
842	T-Cell Lymphoma	3.3%
843	Mantle cell lymphoma	3.3%
844	Bacteremia	3.1%
845	Bronchial Neoplasms	3.1%
846	Diplopia	3.1%
847	Muscle Rigidity	3.1%
848	Muscle Spasticity	3.1%
849	Scotoma	3.1%
850	Photophobia	3.1%
851	Cogwheel Rigidity	3.1%
852	Hemifacial Spasm	3.1%
853	Amaurosis	3.1%
854	Blindness	3.1%
855	Nuchal Rigidity	3.1%
856	Angina Pectoris	3.1%
857	Fungemia	3.1%
858	Multiple Pulmonary Nodules	3.1%
859	Agnosia	3%
860	Apraxias	3%
861	Hallucinations	3%
862	Hemianopsia	3%
863	Hyperacusis	3%
864	Tinnitus	3%
865	Visual Agnosia	3%
866	Anosognosia	3%
867	Wernicke-Korsakoff Syndrome	3%
868	Phonophobia	3%
869	Hearing Loss	3%
870	Cerebellar Ataxia	3%
871	Supratentorial Neoplasms	3%
872	Torticollis	3%
873	Sciatica	3%
874	Urge Incontinence	3%
875	Tardive Dyskinesia	3%
876	Endometrial Neoplasms	3%
877	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	3%
878	Tachycardia, Atrioventricular Nodal Reentry	3%
879	Tachycardia, Ectopic Atrial	3%
880	Tachycardia, Ectopic Junctional	3%
881	Sinus Tachycardia	3%
882	Torsades de Pointes	3%
883	Accelerated Idioventricular Rhythm	3%
884	Leukemia, Large Granular Lymphocytic	3%
885	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	3%
886	Waterhouse-Friderichsen Syndrome	3%
887	Lymphoma, T-Cell, Cutaneous	3%
888	Lymphoma, AIDS-Related	3%
889	Enteropathy-Associated T-Cell Lymphoma	3%
890	Primary Effusion Lymphoma	3%
891	Subacute Combined Degeneration	2.9%
892	Pharyngeal Neoplasms	2.9%
893	Dupuytren Contracture	2.9%
894	Jet Lag Syndrome	2.9%
895	ovarian neoplasm	2.9%
896	Eosinophilic Granuloma	2.9%
897	Reflex, Abnormal	2.9%
898	Hyporeflexia	2.9%
899	Hyperreflexia	2.9%
900	Consciousness Disorders	2.9%
901	Mental Retardation	2.9%
902	Depressed Level of Consciousness	2.9%
903	Mental deficiency	2.9%
904	Intellectual Disability	2.9%
905	Catatonia	2.9%
906	Cellulitis	2.9%
907	Musculoskeletal Pain	2.9%
908	Ophthalmoplegia	2.9%
909	Urticaria Pigmentosa	2.9%
910	External Ophthalmoplegia	2.9%
911	Central Nervous System Cysts	2.9%
912	Endotoxemia	2.9%
913	Amaurosis Fugax	2.8%
914	Blindness, Cortical	2.8%
915	Dyscalculia	2.8%
916	Angina, Unstable	2.8%
917	Deafness	2.8%
918	Hearing Loss, Sudden	2.8%
919	Gerstmann Syndrome	2.8%
920	Hearing Loss, Bilateral	2.8%
921	Hearing Loss, High-Frequency	2.8%
922	Hearing Loss, Mixed Conductive-Sensorineural	2.8%
923	Prosopagnosia	2.8%
924	Apraxia, Ideomotor	2.8%
925	Persistent Vegetative State	2.8%
926	Charles Bonnet Syndrome	2.8%
927	Hearing Loss, Unilateral	2.8%
928	Complete Hearing Loss	2.8%
929	Alien Hand Syndrome	2.8%
930	Deaf Mutism	2.8%
931	Birth Weight	2.8%
932	Aphonia	2.8%
933	Arthralgia	2.8%
934	Bile Duct Neoplasms	2.8%
935	gallbladder neoplasm	2.8%
936	Intestinal Neoplasms	2.8%
937	Leukoplakia, Oral	2.8%
938	Penile Neoplasms	2.8%
939	Prostatic Neoplasms	2.8%
940	Sleep Deprivation	2.8%
941	Stomach Neoplasms	2.8%
942	Polyarthralgia	2.8%
943	Dysphonia	2.8%
944	Brain Stem Neoplasms	2.8%
945	Mycosis Fungoides	2.8%
946	Lymphomatoid Papulosis	2.8%
947	Plasmablastic lymphoma	2.8%
948	Mutism	2.8%
949	Selective Mutism	2.8%
950	Cerebrospinal Fluid Otorrhea	2.8%
951	Cerebrospinal Fluid Rhinorrhea	2.8%
952	Polycythemia Vera	2.8%
953	Romano-Ward Syndrome	2.8%
954	Obesity	2.8%
955	Angina Pectoris, Variant	2.7%
956	Choroid Plexus Papilloma	2.7%
957	Alexia, Pure	2.7%
958	Kernicterus	2.6%
959	Amblyopia	2.5%
960	Amnesia	2.5%
961	Delirium	2.5%
962	Horner Syndrome	2.5%
963	Dissociative Amnesia	2.5%
964	Color blindness	2.5%
965	Global Amnesia	2.5%
966	Hypopharyngeal Neoplasms	2.5%
967	Pleural Effusion, Malignant	2.5%
968	Hypopharyngeal Cancer	2.5%
969	Waldenstrom Macroglobulinemia	2.5%
970	Multiple Myeloma	2.5%
971	Laryngeal neoplasm	2.5%
972	Parotid Neoplasms	2.5%
973	Shoulder Pain	2.5%
974	Prostatic Neoplasms, Castration-Resistant	2.5%
975	Granuloma, Laryngeal	2.5%
976	Nelson Syndrome	2.5%
977	Pediatric Obesity	2.5%
978	Vocal Cord Paralysis	2.5%
979	Myocardial Reperfusion Injury	2.4%
980	Bladder Neoplasm	2.4%
981	Kidney Neoplasm	2.4%
982	Ureteral Neoplasms	2.4%
983	Urethral Neoplasms	2.4%
984	Tinea Pedis	2.4%
985	Retrograde amnesia	2.4%
986	Amnesia, Anterograde	2.4%
987	Tonsillar Neoplasms	2.4%
988	Cerebellar Neoplasms	2.3%
989	Hydrops Fetalis	2.2%
990	Zollinger-Ellison syndrome	2.2%
991	Akathisia, Drug-Induced	2.2%
992	Fetal Weight	2.2%
993	Myalgia	2.2%
994	Dyskinesia, Drug-Induced	2.1%
995	Cecal Neoplasms	2.1%
996	Duodenal Neoplasms	2.1%
997	Burkitt Lymphoma	2.1%
998	Alcohol Withdrawal Seizures	2.1%
999	Philadelphia Chromosome	2%
1000	Amnesia, Transient Global	2%
1001	Sezary Syndrome	2%
1002	Radicular Cyst	2%
1003	Candidemia	2%
1004	Appendiceal Neoplasms	2%
1005	Colonic Neoplasms	2%
1006	Rectal Neoplasms	2%
1007	Nasopharyngeal Neoplasms	1.9%
1008	Auditory Perceptual Disorders	1.9%
1009	Colorectal Neoplasms	1.9%
1010	Basal Ganglia Hemorrhage	1.8%
1011	Putaminal Hemorrhage	1.7%
1012	Ophthalmoplegic Migraine	1.7%
1013	Paranasal Sinus Neoplasms	1.7%
1014	Anus Neoplasms	1.7%
1015	Sigmoid Neoplasms	1.7%
1016	Progressive supranuclear palsy	1.7%
1017	Maxillary Sinus Neoplasms	1.6%
1018	Kearns-Sayre syndrome	1.2%

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