MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Lewy Body Disease

(UMLS:C0752347)

Definition:: A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)
UMLS ID:: C0752347
MeSH ID:: D020961

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.140.079.862.400|C10.228.140.380.422|C10.228.662.600.200|C10.574.531

Classification 2:

Name:

Mental Disorders
MeSH Tree Number(s):: F03.615.400.512

Synonym(s)

Lewy Body Disease

CLBD - Cortical Lewy body disease

Cortical Lewy body disease

DEMENTIA, LEWY BODY

DLBD - Diffuse Lewy body disease

Dementia of the Lewy body type

Dementia with Lewy Bodies

Dementia with Lewy bodies

Dementia with lewy bodies

10.

Diffuse Lewy body disease

11.

LBD

12.

LBD - Lewy body disease

13.

Lewy Body Dementia

14.

Lewy body dementia

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Clozapine	18759705	CTD
2	Donepezil	20505440	CTD
3	Memantine	16087923 16340086	CTD
4	Quetiapine Fumarate	16682107	CTD
5	Rotenone	15280438	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Parkinson Disease	55.6%
2	Multiple System Atrophy	53.2%
3	Huntington Disease	51.5%
4	Dementia, Vascular	46.7%
5	Meningoencephalitis	43.9%
6	Presenile dementia	43.7%
7	Senile dementia	43.7%
8	Creutzfeldt-Jakob disease	41.5%
9	Encephalomyelitis	39.6%
10	Dystonia Musculorum Deformans	37.8%
11	Progressive supranuclear palsy	37.8%
12	Kluver-Bucy Syndrome	37.4%
13	Striatonigral Degeneration	36.7%
14	Meige Syndrome	36.1%
15	Pneumocephalus	35.8%
16	MPTP Poisoning	35.6%
17	Subdural Effusion	35.3%
18	Dandy-Walker Syndrome	34.4%
19	Basal Ganglia Cerebrovascular Disease	34.1%
20	Prion Diseases	33.4%
21	Shy-Drager Syndrome	33.1%
22	Amyotrophic Lateral Sclerosis	32.7%
23	Ocular Motility Disorders	32%
24	Cyclophoria	32%
25	Brain Abscess	31.4%
26	Subacute Combined Degeneration	30.9%
27	Epidural Abscess	30.9%
28	Spinal Muscular Atrophy	30%
29	Progressive Muscular Atrophy	30%
30	Myelitis	29.8%
31	Epilepsy, Post-Traumatic	29.6%
32	Hepatolenticular Degeneration	29.6%
33	Akinetic Mutism	29.5%
34	Anoxic Encephalopathy	29.5%
35	Brain Damage, Chronic	29.5%
36	Cerebellar Diseases	29.5%
37	Encephalitis	29.5%
38	Encephalomalacia	29.5%
39	Epilepsy	29.5%
40	Hydrocephalus	29.5%
41	Congenital Hydrocephalus	29.5%
42	Hypothalamic Diseases	29.5%
43	Thalamic Diseases	29.5%
44	Intracranial Hypertension	29.5%
45	Aura	29.5%
46	Leukoencephalopathy	29.5%
47	Neuroaxonal Dystrophies	29.5%
48	Headache Disorders	29.5%
49	Intracranial Hypotension	29.5%
50	Brain Edema	29.5%
51	Brain Hypoxia	29.5%
52	Aqueductal Stenosis	29.5%
53	Motor Neuron Disease	29.4%
54	Neuroleptic Malignant Syndrome	29.1%
55	Posterior Leukoencephalopathy Syndrome	29%
56	Posterior reversible encephalopathy syndrome	29%
57	Frontotemporal dementia	28.9%
58	Meningitis	28.7%
59	Pachymeningitis	28.7%
60	Spinal Cord Diseases	28.7%
61	Stiff-Person Syndrome	28.6%
62	Brain Injuries	28.2%
63	Brain Neoplasms	28%
64	Asterixis	27.6%
65	Ballismus	27.6%
66	Marchiafava-Bignami Disease	27.6%
67	Limbic Encephalitis	27.4%
68	Leukoencephalopathy, Progressive Multifocal	26.8%
69	Cerebral Ventriculitis	26.7%
70	AIDS Dementia Complex	26.1%
71	Leukomalacia, Periventricular	26%
72	Lupus Vasculitis, Central Nervous System	25.9%
73	Brain Diseases, Metabolic	25.5%
74	Cerebrovascular Disorders	25.5%
75	Cerebrovascular Insufficiency	25.5%
76	Cerebellar Neoplasms	25.4%
77	Vascular Headaches	25.4%
78	Central Nervous System Infection	25.3%
79	Hypoxia-Ischemia, Brain	25.3%
80	Brain Death	25.1%
81	Myelitis, Transverse	24.9%
82	Myoclonic Epilepsy	24.7%
83	Epilepsy, Temporal Lobe	24.7%
84	Epilepsy, Rolandic	24.7%
85	Benign Rolandic Epilepsy	24.7%
86	Leukoencephalitis, Acute Hemorrhagic	24.7%
87	Basal Ganglia Hemorrhage	24.4%
88	Ophthalmoplegic Migraine	24.3%
89	Amnesia, Transient Global	24.2%
90	Myelinolysis, Central Pontine	24.1%
91	Poliomyelitis	24%
92	Lafora Disease	24%
93	Unverricht-Lundborg Syndrome	24%
94	Essential Tremor	24%
95	Familial Tremor	24%
96	Writer's Cramp	24%
97	Restless Legs Syndrome	23.7%
98	Amblyopia	23.5%
99	Lewy Body Disease	23.4%
100	Spinal Cord Injuries	23.1%
101	Pick Disease of the Brain	23.1%
102	Opsoclonus-Myoclonus Syndrome	23%
103	Paraneoplastic Cerebellar Degeneration	22.7%
104	Miller Fisher Syndrome	22.4%
105	Canavan Disease	22.4%
106	Alexander Disease	22.4%
107	Friedreich Ataxia	22.4%
108	Parkinsonian Disorders	22.4%
109	Akathisia, Drug-Induced	22.1%
110	Cranial nerve diseases	21.9%
111	Demyelinating Diseases	21.9%
112	Demyelination	21.9%
113	Neuromuscular Diseases	21.9%
114	Chronobiology Disorders	21.9%
115	Meningitis, Bacterial	21.9%
116	Meningitis, Fungal	21.9%
117	Tauopathies	21.4%
118	Brain Hemorrhage, Traumatic	21.2%
119	Sleep Wake Disorders	21.1%
120	Pituitary Adenoma	20.8%
121	Pituitary Neoplasms	20.8%
122	Polyradiculoneuropathy	20.7%
123	Polyradiculoneuritis	20.7%
124	Chronic Fatigue Syndrome	20.7%
125	Juvenile Myoclonic Epilepsy	20.5%
126	Myoclonic Epilepsies, Progressive	20.5%
127	Putaminal Hemorrhage	20.4%
128	Movement Disorders	20.3%
129	Encephalomyelitis, Acute Disseminated	20.3%
130	Dyskinesia, Drug-Induced	20.2%
131	Carotid Artery Injuries	20.1%
132	Toxoplasmosis, Cerebral	20%
133	Scrapie	20%
134	Basal Ganglia Diseases	19.8%
135	Cerebral Palsy	19.5%
136	Epilepsies, Partial	19.5%
137	Epilepsy, Generalized	19.5%
138	Pseudotumor Cerebri	19.5%
139	Hypertensive Encephalopathy	19.5%
140	Simple Partial Seizures	19.5%
141	Epilepsy, Reflex	19.5%
142	Headache Disorders, Primary	19.5%
143	Headache Disorders, Secondary	19.5%
144	Medication overuse headache	19.5%
145	Progressive bulbar palsy	19.4%
146	Bulbar palsy	19.4%
147	Pituitary Apoplexy	19.4%
148	Vasculitis, Central Nervous System	19.3%
149	Trauma, Nervous System	19.3%
150	Lambert-Eaton Myasthenic Syndrome	19.2%
151	Brain Infarction	19.2%
152	Spinal Cord Neoplasms	19%
153	Nervous System Neoplasms	18.9%
154	Neurologic Manifestations	18.9%
155	Neurotoxicity Syndromes	18.9%
156	Brain Injuries, Diffuse	18.8%
157	Traumatic Brain Injury	18.8%
158	Cerebellar Ataxia	18.8%
159	Supratentorial Neoplasms	18.8%
160	Chorea	18.1%
161	Infarction, Middle Cerebral Artery	18%
162	Infarction, Anterior Cerebral Artery	18%
163	Infarction, Posterior Cerebral Artery	18%
164	Persistent Vegetative State	17.9%
165	Tuberculosis, Meningeal	17.7%
166	Autonomic Dysreflexia	17.7%
167	Complex Regional Pain Syndromes	17.7%
168	Arachnoiditis	17.4%
169	Aseptic Meningitis	17.4%
170	Syringomyelia	17.4%
171	Pneumorrhachis	17.4%
172	Auditory Perceptual Disorders	17.3%
173	Pituitary Diseases	17.2%
174	Guillain-Barre Syndrome	17.1%
175	Carotid Artery Diseases	16.7%
176	Brain Ischemia	16.7%
177	Cerebrovascular accident	16.7%
178	Vasospasm, Intracranial	16.7%
179	Intracranial Arterial Diseases	16.7%
180	Torticollis	16.3%
181	Paraneoplastic Encephalomyelitis	16.2%
182	Cerebral Infarction	15.8%
183	Brain Stem Infarctions	15.8%
184	Moyamoya Disease	15.8%
185	Peripheral Nerve Injuries	15.6%
186	Sleep Disorders, Circadian Rhythm	15.6%
187	Dementia	15.5%
188	Myasthenia Gravis	15.4%
189	Neuromyelitis Optica	15.2%
190	Subacute Sclerosing Panencephalitis	15.1%
191	Mitochondrial Encephalomyopathies	15.1%
192	Adrenoleukodystrophy	15.1%
193	Central Nervous System Fungal Infections	15%
194	Conus Medullaris Syndrome	15%
195	Spinal Cord Vascular Diseases	15%
196	Central Cord Syndrome	15%
197	Subarachnoid Hemorrhage, Traumatic	14.7%
198	Carotid Artery, Internal, Dissection	14.7%
199	Reye Syndrome	14.6%
200	Causalgia	14.6%
201	Intracranial Embolism and Thrombosis	14.6%
202	Hepatic Encephalopathy	14.6%
203	Ataxia Telangiectasia	14.5%
204	Post-Traumatic Headache	14.5%
205	Tension Headache	14.5%
206	Epilepsy, Complex Partial	14.5%
207	Migraine Disorders	14.5%
208	Abdominal Migraine	14.5%
209	Status Migrainosus	14.5%
210	Cervicogenic Headache	14.5%
211	Olfactory Nerve Injuries	14.4%
212	Tuberous Sclerosis	14.3%
213	Diffuse Axonal Injury	14.2%
214	MELAS Syndrome	14.2%
215	Charcot-Marie-Tooth Disease	14.2%
216	Refsum Disease	14.2%
217	Brain Stem Neoplasms	14.2%
218	Lateral Medullary Syndrome	14.2%
219	Meningitis, Cryptococcal	13.8%
220	Meningitis, Listeria	13.8%
221	Meningitis, Haemophilus	13.7%
222	Meningitis, Pneumococcal	13.7%
223	Parasomnia	13.7%
224	Dyssomnias	13.7%
225	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	13.7%
226	Botulism	13.7%
227	Central Nervous System Cysts	13.7%
228	Myotonia Congenita	13.6%
229	Brain Concussion	13.5%
230	Vertebral Artery Dissection	13.4%
231	Tardive Dyskinesia	13.4%
232	Central Nervous System Bacterial Infections	13.3%
233	Brain Diseases, Metabolic, Inborn	13%
234	Facial Nerve Injuries	13%
235	Wernicke Encephalopathy	13%
236	Brain Diseases	12.8%
237	Alice in Wonderland Syndrome	12.7%
238	Brain Contusion	12.7%
239	Empty Sella Syndrome	12.6%
240	Hyperpituitarism	12.6%
241	Hypopituitarism	12.6%
242	Hypophysitis	12.6%
243	Dysautonomia	12.5%
244	Vagus Nerve Disorder	12.5%
245	Glossopharyngeal Neuralgia	12.5%
246	Abducens Nerve Diseases	12.5%
247	Heavy Metal Poisoning, Nervous System	12.5%
248	Neuromuscular Junction Diseases	12.5%
249	Trochlear Nerve Diseases	12.5%
250	Peripheral Nervous System Diseases	12.5%
251	Myotonic Dystrophy	12.5%
252	Cerebral Arterial Diseases	12.4%
253	Vertebrobasilar Insufficiency	12.4%
254	Basilar Artery Stenosis	12.4%
255	Vertebral Artery Stenosis	12.4%
256	Intracranial Hemorrhage, Hypertensive	12.4%
257	Transient Cerebral Ischemia	12.4%
258	Horner Syndrome	12.1%
259	Consciousness Disorders	12.1%
260	Depressed Level of Consciousness	12.1%
261	Cluster Headache	12%
262	Migraine with Aura	12%
263	Familial Hemiplegic Migraine	12%
264	Chronic Paroxysmal Hemicrania	12%
265	SUNCT Syndrome	12%
266	Paroxysmal Hemicrania	12%
267	West Nile Fever	12%
268	Multiple Sclerosis	12%
269	Choroid Plexus Papilloma	11.9%
270	Jet Lag Syndrome	11.9%
271	Myasthenia Gravis, Autoimmune, Experimental	11.8%
272	Reflex Sympathetic Dystrophy	11.8%
273	Nocturnal Myoclonus Syndrome	11.8%
274	Giant Cell Arteritis	11.2%
275	Temporal Arteritis	11.2%
276	Myopathy	11.1%
277	Optic Neuropathy	11.1%
278	Carotid Stenosis	10.9%
279	Intracranial Aneurysm	10.9%
280	Facial Nerve Diseases	10.8%
281	Craniocerebral Trauma	10.8%
282	Intracranial Arteriosclerosis	10.8%
283	Cerebral Atherosclerosis	10.8%
284	Subarachnoid Hemorrhage	10.8%
285	Cerebral Arteriosclerosis	10.8%
286	Cerebral Hemorrhage	10.8%
287	Cerebral Thrombosis	10.8%
288	Intracranial Embolism	10.8%
289	Intracranial Thrombosis	10.8%
290	Kernicterus	10.7%
291	Vestibulocochlear Nerve Diseases	10.7%
292	Decerebrate State	10.7%
293	Hemiparesis	10.7%
294	Hydranencephaly	10.7%
295	Meningism	10.7%
296	Neural Tube Defects	10.7%
297	Paresis	10.7%
298	Seizures	10.7%
299	Sensation Disorders	10.7%
300	Tethered Cord Syndrome	10.7%
301	Central Nervous System Neoplasms	10.7%
302	Complex partial seizures	10.7%
303	Iniencephaly	10.7%
304	Craniorachischisis	10.7%
305	Exencephaly	10.7%
306	Monoparesis	10.7%
307	Septo-Optic Dysplasia	10.7%
308	Cortical Dysplasia	10.7%
309	Neurogenic Inflammation	10.7%
310	Gait Disorders, Neurologic	10.7%
311	Neuromuscular Manifestations	10.7%
312	Malformations of Cortical Development	10.7%
313	Ophthalmoplegia	10.7%
314	External Ophthalmoplegia	10.7%
315	Sweating, Gustatory	10.7%
316	Auriculotemporal Syndrome	10.7%
317	Amnesia	10.5%
318	Delirium	10.5%
319	Dissociative Amnesia	10.5%
320	Global Amnesia	10.5%
321	Hyperprolactinemia	10.3%
322	Acrodynia	10.2%
323	Subclavian Steal Syndrome	10.2%
324	Alstrom Syndrome	10.2%
325	Spinal Cord Ischemia	10.1%
326	Amyloid Neuropathies, Familial	10.1%
327	Tuberculosis, Central Nervous System	10%
328	Cognition Disorders	10%
329	Brachial Plexus Neuritis	9.8%
330	Neuralgic Amyotrophy	9.8%
331	Vocal Cord Paralysis	9.7%
332	Pupil Disorders	9.6%
333	Neurobehavioral Manifestations	9.6%
334	Hematoma, Subdural	9.6%
335	Hematoma, Epidural, Cranial	9.6%
336	Carotid Artery Thrombosis	9.6%
337	Uveomeningoencephalitic Syndrome	9.4%
338	Sturge-Weber Syndrome	9.4%
339	Vertigo	9.4%
340	Alcohol-Induced Disorders, Nervous System	9.4%
341	Cerebrospinal Fluid Otorrhea	9.1%
342	Cerebrospinal Fluid Rhinorrhea	9.1%
343	Neuritis, Autoimmune, Experimental	9.1%
344	Gait Ataxia	9.1%
345	Acromegaly	9%
346	Coma, Post-Head Injury	9%
347	Cerebral Amyloid Angiopathy	9%
348	Sinus Thrombosis, Intracranial	8.9%
349	Tarsal Tunnel Syndrome	8.9%
350	Cauda Equina Syndrome	8.9%
351	Neuroaspergillosis	8.9%
352	Sleep Talking	8.7%
353	Sleep Disorders, Intrinsic	8.7%
354	Fabry Disease	8.7%
355	Neuronal Ceroid-Lipofuscinoses	8.7%
356	Alcohol Withdrawal Seizures	8.7%
357	Optic Nerve Glioma	8.6%
358	Multiple Sclerosis, Chronic Progressive	8.6%
359	Multiple Sclerosis, Relapsing-Remitting	8.6%
360	Voice Disorders	8.5%
361	Voice Disturbance	8.5%
362	Smith-Magenis syndrome	8.3%
363	Dural Arteriovenous Fistula	8.3%
364	Hematoma, Subdural, Intracranial	8.3%
365	Hematoma, Subdural, Chronic	8.3%
366	Hematoma, Subdural, Acute	8.3%
367	Akathisia	8.2%
368	Restlessness	8.2%
369	Psychomotor Agitation	8.2%
370	Pseudorabies	8.1%
371	Cavernous Sinus Thrombosis	8%
372	Sagittal Sinus Thrombosis	8%
373	Neuritis	8%
374	Polyneuritis	8%
375	Radiculitis	8%
376	Polyneuropathy	8%
377	Mononeuritis	8%
378	Mononeuropathies	8%
379	Brachial Plexus Neuropathies	8%
380	Radiculopathy	8%
381	Mononeuropathy Multiplex	8%
382	Nerve Root Compression	8%
383	Cockayne Syndrome	8%
384	Optic Atrophy, Hereditary, Leber	7.9%
385	Neurotic Disorders	7.9%
386	Galactosemias	7.8%
387	Urea Cycle Disorders, Inborn	7.8%
388	Tyrosinemias	7.8%
389	Neurosyphilis	7.8%
390	Carpal Tunnel Syndrome	7.8%
391	neurofibroma	7.8%
392	Alexia, Pure	7.7%
393	Sciatica	7.7%
394	Anterior Spinal Artery Syndrome	7.7%
395	Sleep Bruxism	7.7%
396	Mental Retardation	7.6%
397	Mental deficiency	7.6%
398	Intellectual Disability	7.6%
399	Menkes Kinky Hair Syndrome	7.6%
400	Gait Apraxia	7.5%
401	Reflex, Abnormal	7.4%
402	Hyporeflexia	7.4%
403	Hyperreflexia	7.4%
404	Retrograde amnesia	7.4%
405	Amnesia, Anterograde	7.4%
406	Homocystinuria	7.2%
407	Prolactinoma	7.2%
408	Growth Hormone-Secreting Pituitary Adenoma	7.2%
409	Leigh Disease	7.2%
410	Nelson Syndrome	7.1%
411	Waterhouse-Friderichsen Syndrome	7.1%
412	Lyme Neuroborreliosis	7%
413	Cubital Tunnel Syndrome	6.9%
414	Myositis	6.9%
415	Optic Atrophy	6.9%
416	Optic Neuritis	6.9%
417	Papilledema	6.9%
418	Strabismus	6.9%
419	Tolosa-Hunt Syndrome	6.9%
420	Isaacs syndrome	6.9%
421	Arsenic Poisoning	6.9%
422	Myotonic Disorders	6.9%
423	Myasthenic Syndromes, Congenital	6.9%
424	Diabetic Neuropathies	6.9%
425	Facial Injuries	6.9%
426	Facial Neuralgia	6.9%
427	Diabetic Amyotrophy	6.9%
428	Diabetic Autonomic Neuropathy	6.9%
429	Manganese Poisoning	6.9%
430	Orthostatic intolerance	6.9%
431	Anosmia	6.8%
432	Ataxia	6.8%
433	Athetosis	6.8%
434	Catalepsy	6.8%
435	Dystonia	6.8%
436	Hemiplegia	6.8%
437	Locked-In Syndrome	6.8%
438	Meningeal Neoplasms	6.8%
439	Meningomyelocele	6.8%
440	Muscle Hypertonia	6.8%
441	Muscle hypotonia	6.8%
442	Myoclonus	6.8%
443	Myotonia	6.8%
444	Neuralgia	6.8%
445	Paraplegia	6.8%
446	Pseudobulbar Palsy	6.8%
447	Quadriplegia	6.8%
448	Spasm	6.8%
449	Spastic Paraplegia	6.8%
450	Status Epilepticus	6.8%
451	Taste Disorders	6.8%
452	Tremor	6.8%
453	Spina Bifida	6.8%
454	Monoplegia	6.8%
455	Hypokinesia	6.8%
456	Paraparesis	6.8%
457	Bradykinesia	6.8%
458	Waxy flexibility	6.8%
459	Action Tremor	6.8%
460	Resting Tremor	6.8%
461	Dysosmia	6.8%
462	Quadriparesis	6.8%
463	Mercury Poisoning, Nervous System	6.8%
464	Olfaction Disorders	6.8%
465	Myokymia	6.8%
466	Lead Poisoning, Nervous System	6.8%
467	Vestibular Neuronitis	6.8%
468	Somatosensory Disorders	6.8%
469	Neuropathic pain	6.8%
470	Hyperkinesia	6.8%
471	Intention tremor	6.8%
472	Alexia	6.8%
473	Toxoplasmosis, Congenital	6.8%
474	Dyslexia	6.8%
475	Malaria, Cerebral	6.8%
476	Sleep Deprivation	6.8%
477	Acoustic Neuroma	6.8%
478	Neurocysticercosis	6.7%
479	Alcohol Withdrawal Delirium	6.7%
480	Disorders of Excessive Somnolence	6.3%
481	Sleep Initiation and Maintenance Disorders	6.3%
482	Night Terrors	6.3%
483	Somnambulism	6.3%
484	Transient Insomnia	6.3%
485	Sleep Paralysis	6.3%
486	Chronic Insomnia	6.3%
487	REM Sleep Behavior Disorder	6.3%
488	Hypersomnia	6.3%
489	Hand-Arm Vibration Syndrome	6.2%
490	Classical Lissencephalies and Subcortical Band Heterotopias	6.2%
491	Vision Disorders	6.1%
492	Metamorphopsia	6.1%
493	Visual Impairment	6.1%
494	Fibromyalgia	6.1%
495	Optic Neuropathy, Ischemic	6.1%
496	Anterior Ischemic Optic Neuropathy	6.1%
497	Medial Tibial Stress Syndrome	6.1%
498	Facial Hemiatrophy	6.1%
499	Melkersson-Rosenthal Syndrome	6.1%
500	Mitochondrial Myopathies	6.1%
501	Anisocoria	6%
502	Confusion	6%
503	Facial paralysis	6%
504	Lethargy	6%
505	Memory Disorders	6%
506	Muscle Cramp	6%
507	Perceptual Disorders	6%
508	Psychomotor Disorders	6%
509	Tonic Pupil	6%
510	Eosinophilia-Myalgia Syndrome	6%
511	Anhedonia	6%
512	Disorientation	6%
513	Facial Paresis	6%
514	Memory Loss	6%
515	Hemisensory Neglect	6%
516	Dysacusis	6%
517	Anencephaly	6%
518	Meningocele	6%
519	Muscular Atrophy	6%
520	Respiratory Paralysis	6%
521	Encephalocele	6%
522	Tetany	6%
523	Carbamoyl-Phosphate Synthase I Deficiency Disease	5.9%
524	Zellweger Syndrome	5.8%
525	Separation Anxiety Disorder	5.8%
526	Sciatic Neuropathy	5.8%
527	Ulnar Neuropathies	5.8%
528	Lesion of Sciatic Nerve	5.8%
529	Ulnar Neuritis	5.8%
530	Radial nerve compression	5.8%
531	Radial Tunnel Syndrome	5.8%
532	Peroneal Neuropathies	5.8%
533	Radial Neuropathy	5.8%
534	Median Neuropathy	5.8%
535	Sciatic Nerve Palsy	5.8%
536	Femoral Neuropathy	5.8%
537	Tibial Neuropathy	5.8%
538	Ulnar Nerve Palsy	5.8%
539	Postural Orthostatic Tachycardia Syndrome	5.8%
540	Radial nerve palsy	5.8%
541	Anxiety Disorders	5.7%
542	Avoidant Personality Disorder	5.7%
543	Dissociative disorder	5.7%
544	Frigidity	5.7%
545	Hypoactive Sexual Desire Disorder	5.7%
546	Disruptive, Impulse Control, and Conduct Disorders	5.7%
547	Intermittent Explosive Disorder	5.7%
548	Kleptomania	5.7%
549	Narcissistic Personality Disorder	5.7%
550	Personality Disorders	5.7%
551	Sexual Aversion Disorder	5.7%
552	Somatoform Disorder	5.7%
553	Dissociation	5.7%
554	Motor Disorders	5.7%
555	Mood Disorders	5.7%
556	Schizophrenia Spectrum and Other Psychotic Disorders	5.7%
557	Neurodevelopmental Disorders	5.7%
558	Feeding and Eating Disorders	5.7%
559	Mutism	5.6%
560	Selective Mutism	5.6%
561	Kearns-Sayre syndrome	5.5%
562	Glycogen storage disease type II	5.4%
563	Duane Retraction Syndrome	5.4%
564	Muscle Weakness	5.4%
565	Mobius Syndrome	5.4%
566	Bell Palsy	5.4%
567	Catatonia	5.4%
568	Herpes Zoster Oticus	5.4%
569	Familial Periodic Paralysis	5.3%
570	Aphonia	5.3%
571	Dysphonia	5.3%
572	Neurofibrosarcoma	5.2%
573	Narcolepsy	5.1%
574	Kleine-Levin Syndrome	5.1%
575	Dyscalculia	5.1%
576	Drug abuse	5%
577	Substance Dependence	5%
578	Substance-Related Disorders	5%
579	Drug Dependence	5%
580	Thoracic Outlet Syndrome	5%
581	Esotropia	4.9%
582	Exotropia	4.9%
583	Hypotension, Orthostatic	4.9%
584	Sleep Apnea Syndromes	4.9%
585	Polymyositis	4.9%
586	Post-Exercise Hypotension	4.9%
587	Trigeminal Nerve Disorder	4.9%
588	Dermal Sinus	4.9%
589	Dysgeusia	4.9%
590	Formication	4.9%
591	Hyperalgesia	4.9%
592	Hyperesthesia	4.9%
593	Hypesthesia	4.9%
594	Language Disorders	4.9%
595	Numbness	4.9%
596	Paresthesia	4.9%
597	Paraparesis, Spastic	4.9%
598	Spina Bifida Cystica	4.9%
599	Trismus	4.9%
600	Spina Bifida Occulta	4.9%
601	Epilepsia Partialis Continua	4.9%
602	Hypogeusia	4.9%
603	Meningeal Carcinomatosis	4.9%
604	Brown-Sequard Syndrome	4.9%
605	Lissencephaly	4.9%
606	Polymicrogyria	4.9%
607	Pachygyria	4.9%
608	Schizencephaly	4.9%
609	Lockjaw	4.9%
610	Allodynia	4.9%
611	Lead Poisoning, Nervous System, Childhood	4.9%
612	Lead Poisoning, Nervous System, Adult	4.9%
613	Periventricular Nodular Heterotopia	4.9%
614	Ageusia	4.9%
615	Myalgia	4.8%
616	Polyradiculopathy	4.6%
617	Cataplexy	4.5%
618	Gaucher Disease	4.5%
619	Eye Injuries	4.4%
620	Aicardi's syndrome	4.4%
621	Hoarseness	4.4%
622	Muscular Dystrophy	4.4%
623	Congenital nystagmus	4.4%
624	Orbital Myositis	4.4%
625	Diplopia	4.3%
626	Muscle Rigidity	4.3%
627	Muscle Spasticity	4.3%
628	Scotoma	4.3%
629	Photophobia	4.3%
630	Cogwheel Rigidity	4.3%
631	Hemifacial Spasm	4.3%
632	Amaurosis	4.3%
633	Blindness	4.3%
634	Nuchal Rigidity	4.3%
635	Pyomyositis	4.3%
636	Agnosia	4.3%
637	Apraxias	4.3%
638	Hallucinations	4.3%
639	Hemianopsia	4.3%
640	Hyperacusis	4.3%
641	Tinnitus	4.3%
642	Visual Agnosia	4.3%
643	Anosognosia	4.3%
644	Wernicke-Korsakoff Syndrome	4.3%
645	Phonophobia	4.3%
646	Hearing Loss	4.3%
647	Sarcopenia	4.3%
648	Tay-Sachs Disease	4.1%
649	Holoprosencephaly	4%
650	Sleep Apnea, Obstructive	4%
651	Sleep Apnea, Central	4%
652	Niemann-Pick Disease, Type C	4%
653	Trigeminal Neuralgia	4%
654	Agraphia	4%
655	Anomia	4%
656	Cluttering	4%
657	Language Development Disorders	4%
658	Speech Disorders	4%
659	Syncope	4%
660	Stupor	4%
661	Dysgraphia	4%
662	Presyncope	4%
663	Dyslalia	4%
664	Color blindness	3.9%
665	Cri-du-Chat Syndrome	3.9%
666	Down Syndrome	3.9%
667	Trisomy 21	3.9%
668	POEMS Syndrome	3.8%
669	Meningioma	3.8%
670	Williams Syndrome	3.8%
671	Microcephaly	3.8%
672	Macrocephaly	3.8%
673	Hypokalemic periodic paralysis	3.8%
674	Porencephaly	3.8%
675	Psychoses, Substance-Induced	3.8%
676	Eye Burns	3.5%
677	Aphasia	3.5%
678	Articulation Disorders	3.5%
679	Echolalia	3.5%
680	Stuttering	3.5%
681	Dysphasia	3.5%
682	Welander Distal Myopathy	3.5%
683	Amaurosis Fugax	3.5%
684	Blindness, Cortical	3.5%
685	Rett Syndrome	3.5%
686	Prader-Willi Syndrome	3.5%
687	Deafness	3.5%
688	Hearing Loss, Sudden	3.5%
689	Gerstmann Syndrome	3.5%
690	Hearing Loss, Bilateral	3.5%
691	Hearing Loss, High-Frequency	3.5%
692	Hearing Loss, Mixed Conductive-Sensorineural	3.5%
693	Prosopagnosia	3.5%
694	Apraxia, Ideomotor	3.5%
695	Charles Bonnet Syndrome	3.5%
696	Hearing Loss, Unilateral	3.5%
697	Complete Hearing Loss	3.5%
698	Alien Hand Syndrome	3.5%
699	Deaf Mutism	3.5%
700	Phantom pain	3.4%
701	Phantom Limb Pain	3.4%
702	Adjustment Disorders	3.3%
703	Affective Disorders, Psychotic	3.3%
704	Agoraphobia	3.3%
705	Anorexia Nervosa	3.3%
706	Antisocial Personality Disorder	3.3%
707	Bipolar Disorder	3.3%
708	Body Dysmorphic Disorders	3.3%
709	Borderline Personality Disorder	3.3%
710	Capgras Syndrome	3.3%
711	Child Behavior Disorders	3.3%
712	Developmental Disabilities	3.3%
713	Child Development Disorders, Pervasive	3.3%
714	Claustrophobia	3.3%
715	Conversion disorder	3.3%
716	Cyclothymic Disorder	3.3%
717	Dependent Personality Disorder	3.3%
718	Depressive disorder	3.3%
719	Developmental Coordination Disorder	3.3%
720	Exhibitionism	3.3%
721	Factitious Disorders	3.3%
722	Firesetting Behavior	3.3%
723	Head Banging	3.3%
724	Histrionic Personality Disorder	3.3%
725	Hypochondriasis	3.3%
726	Masochism	3.3%
727	Melancholia	3.3%
728	Motor Skills Disorders	3.3%
729	Dissociative Identity Disorder	3.3%
730	Neurasthenia	3.3%
731	Obsessive-Compulsive Disorder	3.3%
732	Oppositional Defiant Disorder	3.3%
733	Panic Disorder	3.3%
734	Paranoid Personality Disorder	3.3%
735	Pedophilia	3.3%
736	Pseudodementia	3.3%
737	Psychotic Disorders	3.3%
738	Sadism	3.3%
739	Schizoaffective Disorder	3.3%
740	Schizoid Personality Disorder	3.3%
741	Schizophrenia	3.3%
742	Schizophrenia, Childhood	3.3%
743	Schizotypal Personality Disorder	3.3%
744	Stereotypic Movement Disorder	3.3%
745	Transvestism	3.3%
746	Trichotillomania	3.3%
747	Voyeurism	3.3%
748	Attention Deficit and Disruptive Behavior Disorders	3.3%
749	Hyperkinetic Heart Syndrome	3.3%
750	Reactive Attachment Disorder	3.3%
751	Sexual and Gender Disorders	3.3%
752	Gender Dysphoria	3.3%
753	Paranoia	3.3%
754	Compulsive Personality Disorder	3.3%
755	Bulimia Nervosa	3.3%
756	Dysarthria	3.3%
757	Dermatomyositis	3.1%
758	Corneal Scar	3.1%
759	Muscular Dystrophy, Duchenne	3.1%
760	Marijuana Abuse	2.9%
761	Opioid-Related Disorders	2.9%
762	Nicotine Dependence	2.9%
763	Opioid abuse	2.9%
764	Phencyclidine Abuse	2.9%
765	Substance Abuse, Intravenous	2.9%
766	Substance Withdrawal Syndrome	2.9%
767	Tobacco Use Disorder	2.9%
768	Alcohol-Related Disorders	2.9%
769	Amphetamine-Related Disorders	2.9%
770	Cocaine-Related Disorders	2.9%
771	Rubinstein-Taybi Syndrome	2.9%
772	Gambling	2.9%
773	Premature Ejaculation	2.9%
774	Erectile dysfunction	2.9%
775	Fragile X Syndrome	2.8%
776	Corneal Perforation	2.7%
777	Psychoses, Alcoholic	2.6%
778	Neonatal Abstinence Syndrome	2.5%
779	Dyspareunia	2.5%
780	Enuresis	2.2%
781	Combat Disorders	2.2%
782	Dysthymic Disorder	2.2%
783	Hysteria	2.2%
784	Schizophrenia, Catatonic	2.2%
785	Schizophrenia, Disorganized	2.2%
786	Post-Traumatic Stress Disorder	2.2%
787	Attention Deficit Disorder	2.2%
788	Seasonal Affective Disorder	2.2%
789	Conduct Disorder	2.2%
790	Social Communication Disorder	2.2%
791	Psychological Trauma	2.2%
792	Hoarding Disorder	2.2%
793	Phonological Disorder	2.2%
794	Mucopolysaccharidosis II	2.1%
795	Alcohol Use Disorder	1.9%
796	Alcoholic Intoxication	1.9%
797	Heroin Dependence	1.9%
798	Morphine Dependence	1.9%
799	Alcohol abuse	1.9%
800	Depression, Postpartum	1.9%
801	Premenstrual Dysphoric Disorder	1.9%
802	Binge Drinking	1.6%
803	Autistic Disorder	1.6%
804	Asperger Syndrome	1.6%
805	Diurnal Enuresis	1.5%

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