MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Heavy Metal Poisoning, Nervous System

(UMLS:C0751850)

Definition:: Conditions associated with damage or dysfunction of the nervous system caused by exposure to heavy metals, which may cause a variety of central, peripheral, or autonomic nervous system injuries.
UMLS ID:: C0751850
MeSH ID:: D020260

Classification:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.720.475

Synonym(s)

Heavy Metal Poisoning, Nervous System

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Copper		23613148	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Neuroleptic Malignant Syndrome	24.8%
2	Cranial nerve diseases	23.1%
3	Demyelinating Diseases	23.1%
4	Demyelination	23.1%
5	Neuromuscular Diseases	23.1%
6	Chronobiology Disorders	23.1%
7	MPTP Poisoning	21.9%
8	Alcohol-Induced Disorders, Nervous System	20.5%
9	Botulism	20.4%
10	Motor Neuron Disease	19%
11	Akathisia, Drug-Induced	17.1%
12	Multiple System Atrophy	17%
13	Dyskinesia, Drug-Induced	17%
14	Encephalomyelitis	16.3%
15	Prion Diseases	16.3%
16	Autonomic Dysreflexia	16.3%
17	Complex Regional Pain Syndromes	16.3%
18	Trauma, Nervous System	15.8%
19	Stiff-Person Syndrome	15.3%
20	Spinal Muscular Atrophy	15.3%
21	Progressive Muscular Atrophy	15.3%
22	Nervous System Neoplasms	15%
23	Neurologic Manifestations	15%
24	Marchiafava-Bignami Disease	14.9%
25	Ocular Motility Disorders	14.8%
26	Cyclophoria	14.8%
27	Parkinson Disease	14.8%
28	Meningoencephalitis	14.7%
29	Polyradiculoneuropathy	14.5%
30	Polyradiculoneuritis	14.5%
31	Brain Diseases	14.3%
32	Dysautonomia	14.3%
33	Meningitis	14.3%
34	Movement Disorders	14.3%
35	Pachymeningitis	14.3%
36	Spinal Cord Diseases	14.3%
37	Vagus Nerve Disorder	14.3%
38	Glossopharyngeal Neuralgia	14.3%
39	Abducens Nerve Diseases	14.3%
40	Neuromuscular Junction Diseases	14.3%
41	Tauopathies	14.3%
42	Trochlear Nerve Diseases	14.3%
43	Peripheral Nervous System Diseases	14.3%
44	Myelitis	13.6%
45	Progressive bulbar palsy	13.6%
46	Bulbar palsy	13.6%
47	Striatonigral Degeneration	13.5%
48	Amyotrophic Lateral Sclerosis	13.4%
49	Causalgia	13.3%
50	Restless Legs Syndrome	13.2%
51	Spinal Cord Injuries	12.7%
52	Ophthalmoplegic Migraine	12.6%
53	Lewy Body Disease	12.5%
54	Subacute Combined Degeneration	12.5%
55	Guillain-Barre Syndrome	12.5%
56	Reflex Sympathetic Dystrophy	12.4%
57	Subdural Effusion	12.4%
58	Parkinsonian Disorders	12.4%
59	Nocturnal Myoclonus Syndrome	12.4%
60	Peripheral Nerve Injuries	12.3%
61	Dandy-Walker Syndrome	12.2%
62	Pneumocephalus	12.1%
63	Poliomyelitis	12.1%
64	Myasthenia Gravis	12.1%
65	Asterixis	12.1%
66	Ballismus	12.1%
67	Alcohol Withdrawal Seizures	11.3%
68	Epidural Abscess	11.3%
69	Olfactory Nerve Injuries	11.3%
70	Sleep Wake Disorders	11.3%
71	Shy-Drager Syndrome	11.3%
72	Leukoencephalitis, Acute Hemorrhagic	11.2%
73	Progressive supranuclear palsy	11.1%
74	Meige Syndrome	11.1%
75	Myelinolysis, Central Pontine	11.1%
76	Brachial Plexus Neuritis	11.1%
77	Neuralgic Amyotrophy	11.1%
78	Cerebral Ventriculitis	11.1%
79	Miller Fisher Syndrome	11.1%
80	Encephalomyelitis, Acute Disseminated	11%
81	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	11%
82	Dystonia Musculorum Deformans	10.7%
83	Tarsal Tunnel Syndrome	10.5%
84	Cauda Equina Syndrome	10.5%
85	Posterior Leukoencephalopathy Syndrome	10.5%
86	Posterior reversible encephalopathy syndrome	10.5%
87	Akinetic Mutism	10.3%
88	Anoxic Encephalopathy	10.3%
89	Arachnoiditis	10.3%
90	Basal Ganglia Diseases	10.3%
91	Brain Damage, Chronic	10.3%
92	Cerebellar Diseases	10.3%
93	Encephalitis	10.3%
94	Encephalomalacia	10.3%
95	Epilepsy	10.3%
96	Hydrocephalus	10.3%
97	Congenital Hydrocephalus	10.3%
98	Hypothalamic Diseases	10.3%
99	Aseptic Meningitis	10.3%
100	Neuritis	10.3%
101	Polyneuritis	10.3%
102	Radiculitis	10.3%
103	Syringomyelia	10.3%
104	Thalamic Diseases	10.3%
105	Intracranial Hypertension	10.3%
106	Polyneuropathy	10.3%
107	Mononeuritis	10.3%
108	Aura	10.3%
109	Leukoencephalopathy	10.3%
110	Essential Tremor	10.3%
111	Neuroaxonal Dystrophies	10.3%
112	Familial Tremor	10.3%
113	Headache Disorders	10.3%
114	Mononeuropathies	10.3%
115	Intracranial Hypotension	10.3%
116	Brachial Plexus Neuropathies	10.3%
117	Radiculopathy	10.3%
118	Mononeuropathy Multiplex	10.3%
119	Nerve Root Compression	10.3%
120	Brain Edema	10.3%
121	Brain Hypoxia	10.3%
122	Aqueductal Stenosis	10.3%
123	Pneumorrhachis	10.3%
124	Writer's Cramp	10.3%
125	Myelitis, Transverse	10.3%
126	Brain Injuries	10.2%
127	Chronic Fatigue Syndrome	10.1%
128	Brain Neoplasms	10.1%
129	Multiple Sclerosis	10.1%
130	Spinal Cord Neoplasms	10.1%
131	Central Nervous System Infection	10%
132	Myopathy	10%
133	Sleep Disorders, Circadian Rhythm	10%
134	Optic Neuropathy	10%
135	Myoclonic Epilepsy	9.9%
136	Epilepsy, Temporal Lobe	9.9%
137	Epilepsy, Rolandic	9.9%
138	Benign Rolandic Epilepsy	9.9%
139	Neuromyelitis Optica	9.9%
140	Epilepsy, Post-Traumatic	9.9%
141	Opsoclonus-Myoclonus Syndrome	9.7%
142	Lambert-Eaton Myasthenic Syndrome	9.7%
143	Facial Nerve Diseases	9.5%
144	Craniocerebral Trauma	9.5%
145	Parasomnia	9.5%
146	Central Nervous System Cysts	9.5%
147	Dyssomnias	9.5%
148	Facial Nerve Injuries	9.4%
149	Scrapie	9.4%
150	Central Cord Syndrome	9.4%
151	Lafora Disease	9.4%
152	Unverricht-Lundborg Syndrome	9.4%
153	Vestibulocochlear Nerve Diseases	9.3%
154	Decerebrate State	9.3%
155	Hemiparesis	9.3%
156	Hydranencephaly	9.3%
157	Meningism	9.3%
158	Neural Tube Defects	9.3%
159	Paresis	9.3%
160	Seizures	9.3%
161	Sensation Disorders	9.3%
162	Tethered Cord Syndrome	9.3%
163	Central Nervous System Neoplasms	9.3%
164	Complex partial seizures	9.3%
165	Iniencephaly	9.3%
166	Craniorachischisis	9.3%
167	Exencephaly	9.3%
168	Monoparesis	9.3%
169	Septo-Optic Dysplasia	9.3%
170	Cortical Dysplasia	9.3%
171	Neurogenic Inflammation	9.3%
172	Gait Disorders, Neurologic	9.3%
173	Neuromuscular Manifestations	9.3%
174	Malformations of Cortical Development	9.3%
175	Juvenile Myoclonic Epilepsy	9.3%
176	Myoclonic Epilepsies, Progressive	9.3%
177	Presenile dementia	9.2%
178	Senile dementia	9.2%
179	Meningitis, Bacterial	9.2%
180	Meningitis, Fungal	9.2%
181	Sweating, Gustatory	9.2%
182	Auriculotemporal Syndrome	9.2%
183	Chorea	9.2%
184	Cerebellar Neoplasms	9.1%
185	Limbic Encephalitis	8.8%
186	Leukoencephalopathy, Progressive Multifocal	8.8%
187	Horner Syndrome	8.8%
188	Brain Death	8.6%
189	Coma, Post-Head Injury	8.6%
190	Alcohol Withdrawal Delirium	8.6%
191	Charcot-Marie-Tooth Disease	8.5%
192	Huntington Disease	8.5%
193	Cerebral Palsy	8.5%
194	Epilepsies, Partial	8.5%
195	Epilepsy, Generalized	8.5%
196	Pseudotumor Cerebri	8.5%
197	Sciatic Neuropathy	8.5%
198	Hypertensive Encephalopathy	8.5%
199	Ulnar Neuropathies	8.5%
200	Lesion of Sciatic Nerve	8.5%
201	Simple Partial Seizures	8.5%
202	Epilepsy, Reflex	8.5%
203	Ulnar Neuritis	8.5%
204	Radial nerve compression	8.5%
205	Radial Tunnel Syndrome	8.5%
206	Peroneal Neuropathies	8.5%
207	Radial Neuropathy	8.5%
208	Median Neuropathy	8.5%
209	Sciatic Nerve Palsy	8.5%
210	Femoral Neuropathy	8.5%
211	Tibial Neuropathy	8.5%
212	Ulnar Nerve Palsy	8.5%
213	Postural Orthostatic Tachycardia Syndrome	8.5%
214	Radial nerve palsy	8.5%
215	Headache Disorders, Primary	8.5%
216	Headache Disorders, Secondary	8.5%
217	Medication overuse headache	8.5%
218	Creutzfeldt-Jakob disease	8.3%
219	Basal Ganglia Cerebrovascular Disease	8.3%
220	Brain Injuries, Diffuse	8.3%
221	Traumatic Brain Injury	8.3%
222	Cerebellar Ataxia	8.2%
223	Supratentorial Neoplasms	8.2%
224	Torticollis	8.2%
225	Multiple Sclerosis, Chronic Progressive	8.2%
226	Multiple Sclerosis, Relapsing-Remitting	8.2%
227	Brain Abscess	8.2%
228	Ophthalmoplegia	8.2%
229	External Ophthalmoplegia	8.2%
230	Lupus Vasculitis, Central Nervous System	8%
231	Myasthenia Gravis, Autoimmune, Experimental	8%
232	Friedreich Ataxia	7.9%
233	Carpal Tunnel Syndrome	7.9%
234	Vascular Headaches	7.9%
235	Dementia, Vascular	7.8%
236	neurofibroma	7.8%
237	Hypoxia-Ischemia, Brain	7.8%
238	Brain Hemorrhage, Traumatic	7.8%
239	Sciatica	7.8%
240	Tardive Dyskinesia	7.8%
241	Persistent Vegetative State	7.8%
242	Tuberculosis, Meningeal	7.6%
243	Polyradiculopathy	7.6%
244	Post-Traumatic Headache	7.6%
245	Tension Headache	7.6%
246	Epilepsy, Complex Partial	7.6%
247	Migraine Disorders	7.6%
248	Abdominal Migraine	7.6%
249	Status Migrainosus	7.6%
250	Cervicogenic Headache	7.6%
251	Canavan Disease	7.5%
252	Alexander Disease	7.5%
253	Amblyopia	7.4%
254	Myotonia Congenita	7.4%
255	Cubital Tunnel Syndrome	7.4%
256	Diffuse Axonal Injury	7.3%
257	Vasculitis, Central Nervous System	7.3%
258	Paraneoplastic Cerebellar Degeneration	7.3%
259	Brain Stem Neoplasms	7.3%
260	Jet Lag Syndrome	7.3%
261	Cerebrospinal Fluid Otorrhea	7.3%
262	Cerebrospinal Fluid Rhinorrhea	7.3%
263	Neuritis, Autoimmune, Experimental	7.3%
264	Pupil Disorders	7.3%
265	Neurobehavioral Manifestations	7.3%
266	Gait Ataxia	7.3%
267	Cluster Headache	7.1%
268	Migraine with Aura	7.1%
269	Familial Hemiplegic Migraine	7.1%
270	Chronic Paroxysmal Hemicrania	7.1%
271	SUNCT Syndrome	7.1%
272	Paroxysmal Hemicrania	7.1%
273	Carotid Artery Injuries	7%
274	Paraneoplastic Encephalomyelitis	7%
275	Ataxia Telangiectasia	7%
276	Brain Diseases, Metabolic	7%
277	Cerebrovascular Disorders	7%
278	Myositis	7%
279	Optic Atrophy	7%
280	Optic Neuritis	7%
281	Papilledema	7%
282	Strabismus	7%
283	Tolosa-Hunt Syndrome	7%
284	Cerebrovascular Insufficiency	7%
285	Isaacs syndrome	7%
286	Dementia	7%
287	Myotonic Disorders	7%
288	Central Nervous System Fungal Infections	7%
289	Conus Medullaris Syndrome	7%
290	Myasthenic Syndromes, Congenital	7%
291	Spinal Cord Vascular Diseases	7%
292	Uveomeningoencephalitic Syndrome	6.9%
293	Choroid Plexus Papilloma	6.9%
294	Vocal Cord Paralysis	6.9%
295	Sturge-Weber Syndrome	6.8%
296	Vertigo	6.8%
297	Diabetic Neuropathies	6.8%
298	Facial Injuries	6.8%
299	Facial Neuralgia	6.8%
300	Diabetic Amyotrophy	6.8%
301	Diabetic Autonomic Neuropathy	6.8%
302	Sleep Talking	6.8%
303	Sleep Disorders, Intrinsic	6.8%
304	Orthostatic intolerance	6.8%
305	Anosmia	6.7%
306	Ataxia	6.7%
307	Athetosis	6.7%
308	Catalepsy	6.7%
309	Dystonia	6.7%
310	Hemiplegia	6.7%
311	Locked-In Syndrome	6.7%
312	Meningeal Neoplasms	6.7%
313	Meningomyelocele	6.7%
314	Muscle Hypertonia	6.7%
315	Muscle hypotonia	6.7%
316	Myoclonus	6.7%
317	Myotonia	6.7%
318	Neuralgia	6.7%
319	Paraplegia	6.7%
320	Pseudobulbar Palsy	6.7%
321	Quadriplegia	6.7%
322	Spasm	6.7%
323	Spastic Paraplegia	6.7%
324	Status Epilepticus	6.7%
325	Taste Disorders	6.7%
326	Tremor	6.7%
327	Spina Bifida	6.7%
328	Monoplegia	6.7%
329	Hypokinesia	6.7%
330	Paraparesis	6.7%
331	Bradykinesia	6.7%
332	Waxy flexibility	6.7%
333	Action Tremor	6.7%
334	Resting Tremor	6.7%
335	Dysosmia	6.7%
336	Quadriparesis	6.7%
337	Olfaction Disorders	6.7%
338	Myokymia	6.7%
339	Vestibular Neuronitis	6.7%
340	Somatosensory Disorders	6.7%
341	Neuropathic pain	6.7%
342	Hyperkinesia	6.7%
343	Intention tremor	6.7%
344	Leukomalacia, Periventricular	6.7%
345	Alice in Wonderland Syndrome	6.6%
346	Brain Concussion	6.5%
347	Tuberous Sclerosis	6.5%
348	Pituitary Adenoma	6.4%
349	Pituitary Neoplasms	6.4%
350	Myotonic Dystrophy	6.4%
351	Meningitis, Cryptococcal	6.3%
352	Meningitis, Listeria	6.2%
353	Meningitis, Haemophilus	6.2%
354	Meningitis, Pneumococcal	6.2%
355	Frontotemporal dementia	6.2%
356	Basal Ganglia Hemorrhage	6.1%
357	Akathisia	6.1%
358	Restlessness	6.1%
359	Psychomotor Agitation	6.1%
360	Pituitary Diseases	6%
361	Pituitary Apoplexy	6%
362	Toxoplasmosis, Cerebral	5.9%
363	Hepatolenticular Degeneration	5.9%
364	Brain Contusion	5.9%
365	Brain Infarction	5.9%
366	Vertebral Artery Dissection	5.8%
367	Putaminal Hemorrhage	5.8%
368	Amnesia, Transient Global	5.8%
369	Thoracic Outlet Syndrome	5.7%
370	Gait Apraxia	5.7%
371	Optic Nerve Glioma	5.7%
372	Infarction, Middle Cerebral Artery	5.7%
373	Infarction, Anterior Cerebral Artery	5.7%
374	Infarction, Posterior Cerebral Artery	5.7%
375	Voice Disorders	5.6%
376	Voice Disturbance	5.6%
377	Carotid Artery Diseases	5.6%
378	Brain Ischemia	5.6%
379	Esotropia	5.6%
380	Exotropia	5.6%
381	Hypotension, Orthostatic	5.6%
382	Sleep Apnea Syndromes	5.6%
383	Cerebrovascular accident	5.6%
384	Polymyositis	5.6%
385	Kluver-Bucy Syndrome	5.6%
386	Vasospasm, Intracranial	5.6%
387	Spinal Cord Ischemia	5.6%
388	Intracranial Arterial Diseases	5.6%
389	Post-Exercise Hypotension	5.6%
390	Disorders of Excessive Somnolence	5.6%
391	Sleep Initiation and Maintenance Disorders	5.6%
392	Night Terrors	5.6%
393	Somnambulism	5.6%
394	Trigeminal Nerve Disorder	5.6%
395	Transient Insomnia	5.6%
396	Sleep Paralysis	5.6%
397	Chronic Insomnia	5.6%
398	REM Sleep Behavior Disorder	5.6%
399	Hypersomnia	5.6%
400	Dermal Sinus	5.5%
401	Dysgeusia	5.5%
402	Formication	5.5%
403	Hyperalgesia	5.5%
404	Hyperesthesia	5.5%
405	Hypesthesia	5.5%
406	Language Disorders	5.5%
407	Numbness	5.5%
408	Paresthesia	5.5%
409	Paraparesis, Spastic	5.5%
410	Spina Bifida Cystica	5.5%
411	Trismus	5.5%
412	Spina Bifida Occulta	5.5%
413	Epilepsia Partialis Continua	5.5%
414	Hypogeusia	5.5%
415	Mitochondrial Encephalomyopathies	5.5%
416	Meningeal Carcinomatosis	5.5%
417	Brown-Sequard Syndrome	5.5%
418	Lissencephaly	5.5%
419	Polymicrogyria	5.5%
420	Pachygyria	5.5%
421	Schizencephaly	5.5%
422	Lockjaw	5.5%
423	Allodynia	5.5%
424	Periventricular Nodular Heterotopia	5.5%
425	Ageusia	5.5%
426	Tuberculosis, Central Nervous System	5.5%
427	Subacute Sclerosing Panencephalitis	5.5%
428	Cerebral Infarction	5.5%
429	Brain Stem Infarctions	5.5%
430	Smith-Magenis syndrome	5.5%
431	Subarachnoid Hemorrhage, Traumatic	5.5%
432	Carotid Artery, Internal, Dissection	5.5%
433	Hand-Arm Vibration Syndrome	5.5%
434	Dural Arteriovenous Fistula	5.4%
435	Refsum Disease	5.4%
436	Lateral Medullary Syndrome	5.3%
437	Vision Disorders	5.3%
438	Metamorphopsia	5.3%
439	Visual Impairment	5.3%
440	Fibromyalgia	5.3%
441	Optic Neuropathy, Ischemic	5.3%
442	Anterior Ischemic Optic Neuropathy	5.3%
443	Central Nervous System Bacterial Infections	5.3%
444	Medial Tibial Stress Syndrome	5.3%
445	Facial Hemiatrophy	5.2%
446	Melkersson-Rosenthal Syndrome	5.2%
447	Mitochondrial Myopathies	5.2%
448	Empty Sella Syndrome	5.1%
449	Hyperpituitarism	5.1%
450	Hypopituitarism	5.1%
451	Hypophysitis	5.1%
452	Classical Lissencephalies and Subcortical Band Heterotopias	5.1%
453	Anisocoria	5.1%
454	Confusion	5.1%
455	Facial paralysis	5.1%
456	Lethargy	5.1%
457	Memory Disorders	5.1%
458	Muscle Cramp	5.1%
459	Perceptual Disorders	5.1%
460	Psychomotor Disorders	5.1%
461	Tonic Pupil	5.1%
462	Eosinophilia-Myalgia Syndrome	5.1%
463	Anhedonia	5.1%
464	Disorientation	5.1%
465	Facial Paresis	5.1%
466	Memory Loss	5.1%
467	Hemisensory Neglect	5.1%
468	Dysacusis	5.1%
469	Alstrom Syndrome	5.1%
470	Sleep Bruxism	5.1%
471	Anencephaly	5%
472	Meningocele	5%
473	Muscular Atrophy	5%
474	Respiratory Paralysis	5%
475	Encephalocele	5%
476	Tetany	5%
477	Acrodynia	5%
478	Cerebral Arterial Diseases	5%
479	Vertebrobasilar Insufficiency	5%
480	Anterior Spinal Artery Syndrome	5%
481	Basilar Artery Stenosis	5%
482	Vertebral Artery Stenosis	5%
483	Sleep Apnea, Obstructive	5%
484	Sleep Apnea, Central	5%
485	Intracranial Hemorrhage, Hypertensive	5%
486	Transient Cerebral Ischemia	5%
487	Narcolepsy	4.9%
488	Trigeminal Neuralgia	4.9%
489	Kleine-Levin Syndrome	4.9%
490	Agraphia	4.9%
491	Anomia	4.9%
492	Cluttering	4.9%
493	Language Development Disorders	4.9%
494	Speech Disorders	4.9%
495	Syncope	4.9%
496	Stupor	4.9%
497	Dysgraphia	4.9%
498	Presyncope	4.9%
499	Dyslalia	4.9%
500	Alexia	4.9%
501	Dyslexia	4.9%
502	Moyamoya Disease	4.8%
503	Hyperprolactinemia	4.7%
504	Auditory Perceptual Disorders	4.7%
505	Neurofibrosarcoma	4.7%
506	Subclavian Steal Syndrome	4.7%
507	Pick Disease of the Brain	4.7%
508	Cataplexy	4.6%
509	Aphasia	4.6%
510	Articulation Disorders	4.6%
511	Echolalia	4.6%
512	Stuttering	4.6%
513	Dysphasia	4.6%
514	West Nile Fever	4.6%
515	Adrenoleukodystrophy	4.5%
516	Amyloid Neuropathies, Familial	4.5%
517	Dysarthria	4.5%
518	Reflex, Abnormal	4.5%
519	Hyporeflexia	4.5%
520	Hyperreflexia	4.5%
521	Eye Injuries	4.4%
522	MELAS Syndrome	4.4%
523	Giant Cell Arteritis	4.3%
524	Temporal Arteritis	4.3%
525	Hematoma, Subdural	4.3%
526	Hematoma, Epidural, Cranial	4.3%
527	Muscular Dystrophy	4.3%
528	Congenital nystagmus	4.3%
529	Orbital Myositis	4.3%
530	Diplopia	4.2%
531	Muscle Rigidity	4.2%
532	Muscle Spasticity	4.2%
533	Scotoma	4.2%
534	Photophobia	4.2%
535	Cogwheel Rigidity	4.2%
536	Hemifacial Spasm	4.2%
537	Amaurosis	4.2%
538	Blindness	4.2%
539	Nuchal Rigidity	4.2%
540	Reye Syndrome	4.2%
541	Neuroaspergillosis	4.2%
542	Pyomyositis	4.2%
543	Intracranial Embolism and Thrombosis	4.2%
544	Duane Retraction Syndrome	4.2%
545	Hepatic Encephalopathy	4.2%
546	Agnosia	4.1%
547	Apraxias	4.1%
548	Hallucinations	4.1%
549	Hemianopsia	4.1%
550	Hyperacusis	4.1%
551	Tinnitus	4.1%
552	Visual Agnosia	4.1%
553	Anosognosia	4.1%
554	Wernicke-Korsakoff Syndrome	4.1%
555	Phonophobia	4.1%
556	Hearing Loss	4.1%
557	Consciousness Disorders	4.1%
558	Mental Retardation	4.1%
559	Muscle Weakness	4.1%
560	Depressed Level of Consciousness	4.1%
561	Mental deficiency	4.1%
562	Intellectual Disability	4.1%
563	Sarcopenia	4.1%
564	Mobius Syndrome	4.1%
565	Bell Palsy	4.1%
566	Catatonia	4.1%
567	Herpes Zoster Oticus	4.1%
568	Familial Periodic Paralysis	4.1%
569	Aphonia	4%
570	Sleep Deprivation	4%
571	Dysphonia	4%
572	Kearns-Sayre syndrome	4%
573	Hematoma, Subdural, Intracranial	4%
574	Hematoma, Subdural, Chronic	4%
575	Hematoma, Subdural, Acute	4%
576	Acoustic Neuroma	3.9%
577	Optic Atrophy, Hereditary, Leber	3.9%
578	Toxoplasmosis, Congenital	3.8%
579	Eye Burns	3.8%
580	Malaria, Cerebral	3.8%
581	Carotid Stenosis	3.7%
582	Intracranial Aneurysm	3.7%
583	Welander Distal Myopathy	3.7%
584	Neurocysticercosis	3.7%
585	Amaurosis Fugax	3.7%
586	Blindness, Cortical	3.7%
587	Dyscalculia	3.7%
588	Intracranial Arteriosclerosis	3.7%
589	Cerebral Atherosclerosis	3.7%
590	Rett Syndrome	3.7%
591	Subarachnoid Hemorrhage	3.7%
592	Cerebral Arteriosclerosis	3.7%
593	Cerebral Hemorrhage	3.7%
594	Cerebral Thrombosis	3.7%
595	Intracranial Embolism	3.7%
596	Intracranial Thrombosis	3.7%
597	Deafness	3.7%
598	Hearing Loss, Sudden	3.7%
599	Gerstmann Syndrome	3.7%
600	Hearing Loss, Bilateral	3.7%
601	Hearing Loss, High-Frequency	3.7%
602	Hearing Loss, Mixed Conductive-Sensorineural	3.7%
603	Prosopagnosia	3.7%
604	Apraxia, Ideomotor	3.7%
605	Charles Bonnet Syndrome	3.7%
606	Hearing Loss, Unilateral	3.7%
607	Complete Hearing Loss	3.7%
608	Alien Hand Syndrome	3.7%
609	Deaf Mutism	3.7%
610	Mutism	3.6%
611	Selective Mutism	3.6%
612	Acromegaly	3.5%
613	Pseudorabies	3.5%
614	Cerebral Amyloid Angiopathy	3.5%
615	Sinus Thrombosis, Intracranial	3.5%
616	Alexia, Pure	3.4%
617	Amnesia	3.4%
618	Delirium	3.4%
619	Dissociative Amnesia	3.4%
620	Color blindness	3.4%
621	Global Amnesia	3.4%
622	Cri-du-Chat Syndrome	3.4%
623	Down Syndrome	3.4%
624	Brain Diseases, Metabolic, Inborn	3.4%
625	Trisomy 21	3.4%
626	Myalgia	3.3%
627	Cavernous Sinus Thrombosis	3.3%
628	Sagittal Sinus Thrombosis	3.3%
629	POEMS Syndrome	3.3%
630	Meningioma	3.3%
631	Williams Syndrome	3.3%
632	Microcephaly	3.3%
633	Macrocephaly	3.3%
634	Neuronal Ceroid-Lipofuscinoses	3.3%
635	Neurosyphilis	3.3%
636	Hypokalemic periodic paralysis	3.3%
637	Porencephaly	3.3%
638	Dermatomyositis	3.1%
639	Corneal Scar	3.1%
640	Muscular Dystrophy, Duchenne	3%
641	Retrograde amnesia	3%
642	Amnesia, Anterograde	3%
643	Carotid Artery Thrombosis	2.9%
644	Aicardi's syndrome	2.9%
645	Hoarseness	2.9%
646	Cockayne Syndrome	2.9%
647	Waterhouse-Friderichsen Syndrome	2.8%
648	Corneal Perforation	2.8%
649	Prader-Willi Syndrome	2.8%
650	Wernicke Encephalopathy	2.8%
651	AIDS Dementia Complex	2.8%
652	Phantom pain	2.7%
653	Phantom Limb Pain	2.7%
654	Lyme Neuroborreliosis	2.7%
655	Nelson Syndrome	2.7%
656	Menkes Kinky Hair Syndrome	2.7%
657	Holoprosencephaly	2.5%
658	Fragile X Syndrome	2.5%
659	Kernicterus	2.4%
660	Prolactinoma	2.3%
661	Growth Hormone-Secreting Pituitary Adenoma	2.3%
662	Fabry Disease	2.1%
663	Galactosemias	2.1%
664	Urea Cycle Disorders, Inborn	2.1%
665	Tyrosinemias	2.1%
666	Rubinstein-Taybi Syndrome	2.1%
667	Homocystinuria	1.8%
668	Leigh Disease	1.8%
669	Carbamoyl-Phosphate Synthase I Deficiency Disease	1.7%
670	Mucopolysaccharidosis II	1.6%
671	Glycogen storage disease type II	1.5%
672	Zellweger Syndrome	1.3%
673	Gaucher Disease	1.3%
674	Tay-Sachs Disease	1.3%
675	Niemann-Pick Disease, Type C	1.2%

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