MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Chordoma

(UMLS:C0008487)

Definition:: A malignant tumor arising from the embryonic remains of the notochord. It is also called chordocarcinoma, chordoepithelioma, and notochordoma. (Dorland, 27th ed)
UMLS ID:: C0008487
MeSH ID:: D002817

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.465.220

Synonym(s)

Chordoma

CHORDOMA, MALIGNANT

CHORDOMA, SUSCEPTIBILITY TO

chordoma

chordomas

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Imatinib Mesylate	FAERS: 6 Canada Vigilance: 2		Canada Vigilance US FAERS
2	Imatinib Mesylate	FAERS: 3		US FAERS
3	Teriparatide	FAERS: 3		US FAERS
4	ambrisentan	FAERS: 2		US FAERS
5	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	FAERS: 1		US FAERS
6	Clozapine	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
7	Cyclosporine	FAERS: 1		US FAERS
8	Fingolimod Hydrochloride	FAERS: 1		US FAERS
9	Sunitinib	FAERS: 1	24223206	CTD US FAERS
10	Zoledronic Acid	FAERS: 1		US FAERS
11	pazopanib	FAERS: 1		US FAERS
12	teriflunomide	FAERS: 1		US FAERS
13	Bortezomib		24223206	CTD
14	Vincristine		4528471	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Teratoma	46.7%
2	Germinoma	46.7%
3	Teratocarcinoma	46.7%
4	Neuroectodermal Tumors	44.4%
5	Dysgerminoma	34.4%
6	Seminoma	34.4%
7	Neoplasms, Neuroepithelial	34.4%
8	Gliomatosis cerebri	34.4%
9	Craniopharyngioma	32.6%
10	Neuroectodermal Tumor, Melanotic	32.6%
11	Neuroendocrine Tumors	32.6%
12	leukemia	31%
13	Neoplasms, Glandular and Epithelial	31%
14	Dermoid Cyst	30.3%
15	melanoma	30.1%
16	Trophoblastic Neoplasms	28.8%
17	Adenoma, Acidophil	27.4%
18	Ganglioneuroma	27.4%
19	Glioma	27.4%
20	Malignant Glioma	27.4%
21	Medulloblastoma	27.3%
22	Paraganglioma	26.9%
23	Carcinoid Tumor	26.1%
24	Neurilemmoma	26.1%
25	Hutchinson's Melanotic Freckle	25.3%
26	Melanoma, Amelanotic	25.3%
27	Pheochromocytoma	24.1%
28	Astrocytoma	24%
29	Ependymoma	24%
30	oligodendroglioma	24%
31	Ganglioglioma	24%
32	gliosarcoma	24%
33	Anaplastic astrocytoma	24%
34	Anaplastic Oligodendroglioma	24%
35	Malignant Carcinoid Syndrome	23.4%
36	Carcinosarcoma	23.1%
37	Hemangiosarcoma	23.1%
38	lymphangiosarcoma	23.1%
39	Glioblastoma	22.3%
40	Neuroblastoma	22.3%
41	Glioblastoma Multiforme	22.3%
42	Ganglioneuroblastoma	21.5%
43	Choriocarcinoma	21.2%
44	Histiocytic Disorders, Malignant	20.5%
45	Melanoma, Experimental	20.4%
46	Adenoma	20%
47	Ameloblastoma	20%
48	Angiokeratoma	20%
49	Carcinoma	20%
50	Hemangioma	20%
51	hemangiopericytoma	20%
52	Lymphangioma	20%
53	Mesenchymoma	20%
54	Nevus	20%
55	Hepatoblastoma	20%
56	Mixed Tumor, Mullerian	20%
57	Angiofibroma	20%
58	Sarcoma	20%
59	Epithelioma	20%
60	Basal cell carcinoma	19.6%
61	Carcinoma, Papillary	19.6%
62	Squamous cell carcinoma	19.6%
63	Chondrosarcoma	19.6%
64	Cystadenoma	19.6%
65	leiomyosarcoma	19.6%
66	liposarcoma	19.6%
67	Mesothelioma	19.6%
68	synovial sarcoma	19.6%
69	Angiomyolipoma	19.6%
70	Clear Cell Sarcoma of Soft Tissue	19.6%
71	Alveolar Soft Part Sarcoma	19.6%
72	Sarcoma, Myeloid	19.6%
73	Carcinoma, Basal Cell	19.6%
74	Carcinoma 256, Walker	18.7%
75	Hamartoma	18.5%
76	Neoplasms, Hormone-Dependent	18.5%
77	Neoplasms, Multiple Primary	18.5%
78	Paraneoplastic Syndromes	18.5%
79	Precancerous Conditions	18.5%
80	Neoplasms, Second Primary	18.5%
81	Carcinoid Heart Disease	18%
82	Cystadenocarcinoma	17.8%
83	Fibrosarcoma	17.8%
84	Osteosarcoma	17.8%
85	Mucoepidermoid Carcinoma	17.8%
86	Meningioma	17.4%
87	Leukemia, Plasma Cell	17.2%
88	Adenofibroma	17%
89	Fibroadenoma	17%
90	Malignant Fibrous Histiocytoma	17%
91	Carcinoma, Ehrlich Tumor	16.9%
92	Carcinoma, Lewis Lung	16.9%
93	Hydatidiform Mole	16.5%
94	Bowen's Disease	16.1%
95	Rhabdomyosarcoma	16.1%
96	Giant Cell Tumor of Bone	16.1%
97	Composite Lymphoma	15.8%
98	Dermatofibrosarcoma	15.3%
99	Dermatofibrosarcoma Protuberans	15.3%
100	Lymphoma	15.3%
101	Retinoblastoma	15.2%
102	Leukemia, Experimental	15.1%
103	Adenocarcinoma	14.8%
104	Carcinoma in Situ	14.8%
105	Carcinoma, Transitional Cell	14.8%
106	Phyllodes Tumor	14.8%
107	Hemangioendothelioma	14.8%
108	Lipoma	14.8%
109	Myoma	14.8%
110	Myxoma	14.8%
111	Neuroma	14.8%
112	Papilloma	14.8%
113	Pseudomyxoma Peritonei	14.8%
114	Papillomatosis	14.8%
115	Angiolipoma	14.8%
116	Myelolipoma	14.8%
117	Neoplasms, Bone Tissue	14.8%
118	Neoplasms, Fibrous Tissue	14.8%
119	Smooth Muscle Tumor	14.8%
120	Adenomatosis, Pulmonary	14.8%
121	Adenomatous Polyps	14.8%
122	Carcinoma, Large Cell	14.8%
123	Carcinoma, Small Cell	14.8%
124	Desmoplastic Small Round Cell Tumor	14.8%
125	Chondroma	14.8%
126	Enchondroma	14.8%
127	Alveolar rhabdomyosarcoma	14.4%
128	Leukemia L1210	14.3%
129	Leukemia P388	14.3%
130	Acanthoma	14.3%
131	Carcinoma, Lobular	13.4%
132	Plasmacytoma	13.3%
133	Malignant histiocytosis	13.2%
134	Histiocytic sarcoma	13.2%
135	Sarcoma 180	12.6%
136	Endometrial Stromal Sarcoma	12.6%
137	Sarcoma, Experimental	12.5%
138	Thymoma	12.4%
139	Leukemia, Radiation-Induced	12.2%
140	Adenoid Cystic Carcinoma	12.2%
141	Cyst	12.2%
142	fibroma	12.2%
143	Fibromatosis	12.2%
144	Neoplastic Processes	12.2%
145	Neoplastic Syndromes, Hereditary	12.2%
146	Osteoblastoma	12.2%
147	Osteoma	12.2%
148	Pregnancy Complications, Neoplastic	12.2%
149	Rhabdomyoma	12.2%
150	Chondromatosis	12.2%
151	Adenocarcinoma, Clear Cell	12.2%
152	Cholangiocarcinoma	12.2%
153	Cervical Intraepithelial Neoplasia	12.2%
154	Hemangioblastoma	12.2%
155	Lymphoma, Extranodal NK-T-Cell	12.2%
156	Neoplasms, Experimental	11.9%
157	Lymphangioleiomyomatosis	11.7%
158	Neurofibrosarcoma	11.6%
159	Acoustic Neuroma	11.3%
160	Vipoma	11%
161	Fibromatosis, Aggressive	10.9%
162	Fibromatosis, Abdominal	10.9%
163	Klatskin Tumor	10.9%
164	Abdominal Neoplasms	10.3%
165	Erythroplasia	10.3%
166	Follicular cyst	10.3%
167	Head and Neck Neoplasms	10.3%
168	Mucocele	10.3%
169	Pilonidal Cyst	10.3%
170	Soft Tissue Neoplasms	10.3%
171	Thoracic Neoplasms	10.3%
172	Thyroglossal Cyst	10.3%
173	Synovial Cyst	10.3%
174	Aberrant Crypt Foci	10.3%
175	Optic Nerve Glioma	10.1%
176	Hodgkin Disease	9.8%
177	Lymphoma, Non-Hodgkin	9.8%
178	Leukemia, Myelomonocytic, Chronic	9.8%
179	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	9.8%
180	Multiple Endocrine Neoplasia	9.2%
181	Neoplasms, Radiation-Induced	8.8%
182	Lymphomatoid Granulomatosis	8.8%
183	Paraneoplastic Encephalomyelitis	8.6%
184	Mammary Neoplasms, Experimental	8.4%
185	Carcinoma, Pancreatic Ductal	8.3%
186	Mastocytoma	8.2%
187	Mastocytosis, Systemic	8.1%
188	Leukemia, Myeloid, Chronic-Phase	8.1%
189	Primary amyloidosis	7.9%
190	Hepatocellular Adenoma	7.9%
191	Basal Cell Nevus Syndrome	7.7%
192	Mastocytosis	7.6%
193	Sturge-Weber Syndrome	7.6%
194	Nephroblastoma	7.5%
195	Gastrointestinal Stromal Tumors	7.4%
196	Hemangioma, Cavernous	7.4%
197	Digestive System Neoplasms	7.3%
198	Endocrine Gland Neoplasms	7.3%
199	Eye Neoplasms	7.3%
200	Leukemia, T-Cell	7.3%
201	Nervous System Neoplasms	7.3%
202	Leukemia, B-Cell	7.3%
203	neurofibroma	7.3%
204	Lymphoma, Follicular	7.3%
205	T-Cell Lymphoma	7.3%
206	Mantle cell lymphoma	7.3%
207	Bone neoplasms	7%
208	Leukoplakia	7%
209	Lymphocele	7%
210	Pancreatic Cyst	7%
211	Skin Neoplasms	7%
212	Hematologic Neoplasms	7%
213	Barrett Esophagus	6.8%
214	Breast Cyst	6.8%
215	Actinic keratosis	6.8%
216	Mediastinal Cyst	6.8%
217	Neoplasm Invasiveness	6.8%
218	Neoplasm Metastasis	6.8%
219	Neoplasm Recurrence, Local	6.8%
220	Parovarian Cyst	6.8%
221	Pericardial Cyst	6.8%
222	Splenic Neoplasms	6.8%
223	Thymic Cyst	6.8%
224	Carcinogenesis	6.8%
225	Myxoid cyst	6.8%
226	Metastasis	6.8%
227	Mesoblastic Nephroma	6.7%
228	Retroperitoneal Neoplasms	6.7%
229	Prolactinoma	6.5%
230	Growth Hormone-Secreting Pituitary Adenoma	6.5%
231	Tuberous Sclerosis	6.1%
232	Multiple Endocrine Neoplasia Type 1	6%
233	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	6%
234	Leukemia, Large Granular Lymphocytic	6%
235	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	6%
236	Lymphoma, T-Cell, Cutaneous	6%
237	Lymphoma, AIDS-Related	6%
238	Enteropathy-Associated T-Cell Lymphoma	6%
239	Primary Effusion Lymphoma	6%
240	insulinoma	5.7%
241	Waldenstrom Macroglobulinemia	5.7%
242	Multiple Myeloma	5.7%
243	Dupuytren Contracture	5.6%
244	granulosa cell tumor	5.5%
245	Carcinoma, Ovarian Epithelial	5.5%
246	Urticaria Pigmentosa	5.5%
247	Parathyroid Neoplasms	5.5%
248	Peritoneal Neoplasms	5.5%
249	Thyroid Neoplasm	5.5%
250	Thyroid carcinoma	5.5%
251	Gastrinoma	5.4%
252	Glucagonoma	5.4%
253	Mycosis Fungoides	5.4%
254	Lymphomatoid Papulosis	5.4%
255	Plasmablastic lymphoma	5.4%
256	Adrenocortical carcinoma	5.4%
257	Adenomatous Polyposis Coli	5.1%
258	Corpus Luteum Cyst	5%
259	Ovarian Cysts	5%
260	Liver Neoplasms, Experimental	5%
261	Leydig Cell Tumor	4.9%
262	Tracheal Neoplasms	4.8%
263	Leukoplakia, Oral	4.6%
264	Paraneoplastic Cerebellar Degeneration	4.6%
265	Pancreatic Neoplasm	4.6%
266	Renal Cell Carcinoma	4.6%
267	Papillary Renal Cell Carcinoma	4.6%
268	Mouth Neoplasms	4.5%
269	Central Nervous System Neoplasms	4.5%
270	Vascular Neoplasms	4.5%
271	Thymus Neoplasms	4.5%
272	Nasopharyngeal carcinoma	4.5%
273	Carcinoma, Endometrioid	4.4%
274	Genital Neoplasms, Female	4.4%
275	Pancreatic Pseudocyst	4.4%
276	Lymphatic Metastasis	4.4%
277	Neoplasms, Unknown Primary	4.4%
278	Leukemic Infiltration	4.4%
279	Breast Neoplasms, Male	4.4%
280	Neoplasm Micrometastasis	4.4%
281	Triple Negative Breast Neoplasms	4.4%
282	Choledochal Cyst	4.1%
283	Burkitt Lymphoma	4%
284	Peutz-Jeghers Syndrome	4%
285	Thyroid Nodule	3.9%
286	Esophageal Neoplasms	3.9%
287	Limbic Encephalitis	3.8%
288	Denys-Drash Syndrome	3.8%
289	Sezary Syndrome	3.6%
290	Adrenal Gland Neoplasms	3.4%
291	Gastrointestinal Neoplasms	3.4%
292	Genital Neoplasms, Male	3.4%
293	Liver neoplasms	3.4%
294	Uveal Neoplasms	3.4%
295	Urologic Neoplasms	3.4%
296	Lambert-Eaton Myasthenic Syndrome	3.3%
297	Testicular Neoplasms	3.3%
298	Sebaceous Gland Neoplasms	3.3%
299	Spinal Neoplasms	3.3%
300	Bone Marrow Neoplasms	3.3%
301	Meningeal Neoplasms	3.3%
302	Polycystic Ovary Syndrome	3.3%
303	Opsoclonus-Myoclonus Syndrome	2.9%
304	Meningeal Carcinomatosis	2.7%
305	Palatal Neoplasms	2.6%
306	Ear Neoplasms	2.6%
307	Eyelid Neoplasms	2.6%
308	Lung Neoplasms	2.6%
309	Pleural Neoplasms	2.6%
310	Myelitis, Transverse	2.6%
311	Nose Neoplasms	2.6%
312	Cell Transformation, Viral	2.5%
313	Brain Neoplasms	2.5%
314	Salivary Gland Neoplasms	2.5%
315	Spinal Cord Neoplasms	2.5%
316	Tongue Neoplasms	2.5%
317	Uterine Neoplasms	2.4%
318	Vaginal Neoplasms	2.4%
319	Vulvar Neoplasms	2.4%
320	Uterine Cancer	2.4%
321	Fallopian Tube Neoplasms	2.4%
322	Xeroderma Pigmentosum	2.2%
323	Pituitary Adenoma	2.2%
324	Pituitary Neoplasms	2.2%
325	ovarian neoplasm	2.2%
326	Bronchial Neoplasms	2.1%
327	Pharyngeal Neoplasms	2.1%
328	Multiple Pulmonary Nodules	2.1%
329	Supratentorial Neoplasms	2%
330	Central Nervous System Cysts	2%
331	Endometrial Neoplasms	2%
332	Bile Duct Neoplasms	2%
333	gallbladder neoplasm	2%
334	Intestinal Neoplasms	2%
335	Penile Neoplasms	2%
336	Prostatic Neoplasms	2%
337	Stomach Neoplasms	2%
338	Polycythemia Vera	1.9%
339	Brain Stem Neoplasms	1.8%
340	Laryngeal neoplasm	1.7%
341	Choroid Plexus Papilloma	1.7%
342	Hypopharyngeal Neoplasms	1.7%
343	Pleural Effusion, Malignant	1.7%
344	Hypopharyngeal Cancer	1.7%
345	Zollinger-Ellison syndrome	1.6%
346	Bladder Neoplasm	1.6%
347	Kidney Neoplasm	1.6%
348	Ureteral Neoplasms	1.6%
349	Urethral Neoplasms	1.6%
350	Parotid Neoplasms	1.6%
351	Prostatic Neoplasms, Castration-Resistant	1.6%
352	Nelson Syndrome	1.6%
353	Tonsillar Neoplasms	1.5%
354	Cerebellar Neoplasms	1.4%
355	Cecal Neoplasms	1.3%
356	Duodenal Neoplasms	1.3%
357	Radicular Cyst	1.2%
358	Appendiceal Neoplasms	1.2%
359	Colonic Neoplasms	1.2%
360	Rectal Neoplasms	1.2%
361	Nasopharyngeal Neoplasms	1.2%
362	Colorectal Neoplasms	1.2%
363	Paranasal Sinus Neoplasms	1%
364	Anus Neoplasms	1%
365	Sigmoid Neoplasms	1%
366	Maxillary Sinus Neoplasms	0.9%

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