MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

gliosarcoma

(UMLS:C0206726)

Definition:: Rare mixed tumors of the brain and rarely the spinal cord which contain malignant neuroectodermal (glial) and mesenchymal components, including spindle-shaped fibrosarcoma cells. These tumors are highly aggressive and present primarily in adults as rapidly expanding mass lesions. They may arise in tissue that has been previously irradiated. (From Br J Neurosurg 1995 Apr;9(2):171-8)
UMLS ID:: C0206726
MeSH ID:: D018316

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.465.625.600.380.400|C04.557.470.670.380.400|C04.557.580.625.600.380.400

Synonym(s)

gliosarcoma

Glioblastoma with a Sarcomatous Component

Glioblastoma with sarcomatous component

Gliosarcoma

gliosarcoma; unspecified site

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Temozolomide	FAERS: 4	20173548	CTD US FAERS
2	Dabigatran	FAERS: 2		US FAERS
3	Imatinib Mesylate	FAERS: 1		US FAERS
4	3,4-dihydroxybenzohydroxamic acid		15133626	CTD
5	Camptothecin		15197484	CTD
6	Carmustine		View details 15133626 15197484 16533777 20173548	CTD
7	Cyclophosphamide		9766669 11389073	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Medulloblastoma	57.5%
2	Astrocytoma	55.8%
3	Ependymoma	55.8%
4	oligodendroglioma	55.8%
5	Ganglioglioma	55.8%
6	Anaplastic astrocytoma	55.8%
7	Anaplastic Oligodendroglioma	55.8%
8	Ganglioneuroma	46%
9	Glioblastoma	41.7%
10	Glioblastoma Multiforme	41.7%
11	Craniopharyngioma	34.4%
12	Neuroectodermal Tumor, Melanotic	34.4%
13	Neuroendocrine Tumors	34.4%
14	leukemia	31.7%
15	Retinoblastoma	29.5%
16	melanoma	28.7%
17	Optic Nerve Glioma	27%
18	Adenoma, Acidophil	27%
19	Histiocytic Disorders, Malignant	25.5%
20	Adenoma	24.8%
21	Carcinoma	24.8%
22	Epithelioma	24.8%
23	Meningioma	24.6%
24	Chordoma	24%
25	Teratoma	24%
26	Germinoma	24%
27	Teratocarcinoma	24%
28	Trophoblastic Neoplasms	23.5%
29	Carcinoid Tumor	23.5%
30	Neurilemmoma	23%
31	Basal cell carcinoma	22.9%
32	Carcinoma, Papillary	22.9%
33	Squamous cell carcinoma	22.9%
34	Cystadenoma	22.9%
35	Mesothelioma	22.9%
36	Carcinoma, Basal Cell	22.9%
37	Neuroblastoma	22.8%
38	Neoplasms, Germ Cell and Embryonal	21.3%
39	Germ Cell Cancer	21.3%
40	Lymphoma	21.3%
41	Carcinosarcoma	21.2%
42	Hemangiosarcoma	21.2%
43	lymphangiosarcoma	21.2%
44	Hamartoma	21%
45	Neoplasms, Hormone-Dependent	21%
46	Neoplasms, Multiple Primary	21%
47	Paraneoplastic Syndromes	21%
48	Precancerous Conditions	21%
49	Neoplasms, Second Primary	21%
50	Paraganglioma	20.9%
51	Neoplasms, Glandular and Epithelial	20.7%
52	Carcinoma, Ehrlich Tumor	20.1%
53	Carcinoma, Lewis Lung	20.1%
54	Dermoid Cyst	19.5%
55	Composite Lymphoma	19.4%
56	Melanoma, Experimental	19.1%
57	Ganglioneuroblastoma	19%
58	Cystadenocarcinoma	18.7%
59	Mucoepidermoid Carcinoma	18.7%
60	Leukemia, Experimental	18.5%
61	Neuroectodermal Tumors	18.4%
62	Hutchinson's Melanotic Freckle	18.2%
63	Melanoma, Amelanotic	18.2%
64	Leukemia, Plasma Cell	17.6%
65	Carcinoma 256, Walker	17.5%
66	Cyst	17%
67	Neoplastic Processes	17%
68	Neoplastic Syndromes, Hereditary	17%
69	Pregnancy Complications, Neoplastic	17%
70	Ameloblastoma	16.8%
71	Angiokeratoma	16.8%
72	Hemangioma	16.8%
73	hemangiopericytoma	16.8%
74	Lymphangioma	16.8%
75	Mesenchymoma	16.8%
76	Nevus	16.8%
77	Hepatoblastoma	16.8%
78	Mixed Tumor, Mullerian	16.8%
79	Angiofibroma	16.8%
80	Sarcoma	16.8%
81	Neoplasms, Experimental	16.8%
82	Carcinoma, Lobular	16.7%
83	Choriocarcinoma	16.2%
84	Malignant Carcinoid Syndrome	16.2%
85	Neoplasms, Neuroepithelial	16%
86	Gliomatosis cerebri	16%
87	Leukemia, Radiation-Induced	16%
88	Acanthoma	16%
89	Chondrosarcoma	15.3%
90	leiomyosarcoma	15.3%
91	liposarcoma	15.3%
92	synovial sarcoma	15.3%
93	Angiomyolipoma	15.3%
94	Clear Cell Sarcoma of Soft Tissue	15.3%
95	Alveolar Soft Part Sarcoma	15.3%
96	Sarcoma, Myeloid	15.3%
97	Adenofibroma	14.7%
98	Fibroadenoma	14.7%
99	Bowen's Disease	14.6%
100	Adenocarcinoma	14.3%
101	Carcinoma in Situ	14.3%
102	Carcinoma, Transitional Cell	14.3%
103	Papilloma	14.3%
104	Pseudomyxoma Peritonei	14.3%
105	Papillomatosis	14.3%
106	Adenomatosis, Pulmonary	14.3%
107	Adenomatous Polyps	14.3%
108	Carcinoma, Large Cell	14.3%
109	Carcinoma, Small Cell	14.3%
110	Pheochromocytoma	14.2%
111	Neoplasms, Radiation-Induced	14%
112	Multiple Endocrine Neoplasia	13.8%
113	Plasmacytoma	13.5%
114	Sarcoma, Experimental	13.5%
115	Dysgerminoma	13.5%
116	Neuroma	13.5%
117	Seminoma	13.5%
118	Malignant histiocytosis	13.5%
119	Histiocytic sarcoma	13.5%
120	Thymoma	13.4%
121	Endometrial Stromal Sarcoma	12.9%
122	Fibrosarcoma	12.4%
123	Osteosarcoma	12.4%
124	Leukemia L1210	12.2%
125	Leukemia P388	12.2%
126	Hodgkin Disease	11.2%
127	Lymphoma, Non-Hodgkin	11.2%
128	Paraneoplastic Encephalomyelitis	11%
129	Lymphangioleiomyomatosis	11%
130	Malignant Fibrous Histiocytoma	10.9%
131	Carcinoid Heart Disease	10.9%
132	Mammary Neoplasms, Experimental	10.9%
133	Tuberous Sclerosis	10.8%
134	Nephroblastoma	10.8%
135	Abdominal Neoplasms	10.6%
136	Erythroplasia	10.6%
137	Follicular cyst	10.6%
138	Head and Neck Neoplasms	10.6%
139	Mucocele	10.6%
140	Pilonidal Cyst	10.6%
141	Soft Tissue Neoplasms	10.6%
142	Thoracic Neoplasms	10.6%
143	Thyroglossal Cyst	10.6%
144	Synovial Cyst	10.6%
145	Aberrant Crypt Foci	10.6%
146	Basal Cell Nevus Syndrome	10.4%
147	Hepatocellular Adenoma	10.1%
148	Acoustic Neuroma	9.8%
149	Primary amyloidosis	9.7%
150	Phyllodes Tumor	9.5%
151	Glioma	9.5%
152	Hemangioendothelioma	9.5%
153	Lipoma	9.5%
154	Myoma	9.5%
155	Myxoma	9.5%
156	Angiolipoma	9.5%
157	Myelolipoma	9.5%
158	Neoplasms, Bone Tissue	9.5%
159	Neoplasms, Fibrous Tissue	9.5%
160	Smooth Muscle Tumor	9.5%
161	Desmoplastic Small Round Cell Tumor	9.5%
162	Malignant Glioma	9.5%
163	Chondroma	9.5%
164	Enchondroma	9.5%
165	Rhabdomyosarcoma	9.5%
166	Giant Cell Tumor of Bone	9.5%
167	Lymphomatoid Granulomatosis	9.4%
168	Sarcoma 180	9.3%
169	Neurofibrosarcoma	9.2%
170	Adenoid Cystic Carcinoma	9.1%
171	Adenocarcinoma, Clear Cell	9.1%
172	Cholangiocarcinoma	9.1%
173	Cervical Intraepithelial Neoplasia	9.1%
174	neurofibroma	9%
175	Carcinoma, Pancreatic Ductal	8.9%
176	Prolactinoma	8.8%
177	Growth Hormone-Secreting Pituitary Adenoma	8.8%
178	Digestive System Neoplasms	8.8%
179	Endocrine Gland Neoplasms	8.8%
180	Eye Neoplasms	8.8%
181	Nervous System Neoplasms	8.8%
182	Bone neoplasms	8.6%
183	Leukoplakia	8.6%
184	Lymphocele	8.6%
185	Pancreatic Cyst	8.6%
186	Skin Neoplasms	8.6%
187	Hematologic Neoplasms	8.6%
188	Barrett Esophagus	8.5%
189	Breast Cyst	8.5%
190	Actinic keratosis	8.5%
191	Mediastinal Cyst	8.5%
192	Neoplasm Invasiveness	8.5%
193	Neoplasm Metastasis	8.5%
194	Neoplasm Recurrence, Local	8.5%
195	Parovarian Cyst	8.5%
196	Pericardial Cyst	8.5%
197	Splenic Neoplasms	8.5%
198	Thymic Cyst	8.5%
199	Carcinogenesis	8.5%
200	Myxoid cyst	8.5%
201	Metastasis	8.5%
202	Mesoblastic Nephroma	8.3%
203	Dermatofibrosarcoma	8.1%
204	Dermatofibrosarcoma Protuberans	8.1%
205	Carcinoma, Ovarian Epithelial	7.8%
206	Vipoma	7.8%
207	Hydatidiform Mole	7.7%
208	Leukemia, Myelomonocytic, Chronic	7.6%
209	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	7.6%
210	Waldenstrom Macroglobulinemia	7.6%
211	Multiple Myeloma	7.6%
212	Multiple Endocrine Neoplasia Type 1	7.3%
213	Corpus Luteum Cyst	7%
214	Ovarian Cysts	7%
215	Adenomatous Polyposis Coli	7%
216	Liver Neoplasms, Experimental	6.9%
217	Parathyroid Neoplasms	6.6%
218	Peritoneal Neoplasms	6.6%
219	Thyroid Neoplasm	6.6%
220	Thyroid carcinoma	6.6%
221	Alveolar rhabdomyosarcoma	6.6%
222	Mastocytosis	6.5%
223	Sturge-Weber Syndrome	6.5%
224	Klatskin Tumor	6.5%
225	Gastrointestinal Stromal Tumors	6.5%
226	Hemangioma, Cavernous	6.4%
227	Leukemia, T-Cell	6.4%
228	Leukemia, B-Cell	6.4%
229	Lymphoma, Follicular	6.3%
230	T-Cell Lymphoma	6.3%
231	Mantle cell lymphoma	6.3%
232	gliosarcoma	6.3%
233	Nasopharyngeal carcinoma	6.3%
234	Choledochal Cyst	6.2%
235	Peutz-Jeghers Syndrome	6%
236	fibroma	5.9%
237	Fibromatosis	5.9%
238	Osteoblastoma	5.9%
239	Osteoma	5.9%
240	Rhabdomyoma	5.9%
241	Chondromatosis	5.9%
242	Hemangioblastoma	5.9%
243	Lymphoma, Extranodal NK-T-Cell	5.9%
244	Pancreatic Neoplasm	5.9%
245	insulinoma	5.8%
246	granulosa cell tumor	5.7%
247	Retroperitoneal Neoplasms	5.6%
248	Adrenocortical carcinoma	5.6%
249	Tracheal Neoplasms	5.2%
250	Leukoplakia, Oral	5.1%
251	Paraneoplastic Cerebellar Degeneration	5.1%
252	Renal Cell Carcinoma	4.9%
253	Papillary Renal Cell Carcinoma	4.9%
254	Mastocytoma	4.8%
255	Mastocytosis, Systemic	4.8%
256	Leukemia, Myeloid, Chronic-Phase	4.7%
257	Gastrinoma	4.7%
258	Glucagonoma	4.7%
259	Carcinoma, Endometrioid	4.7%
260	Mouth Neoplasms	4.6%
261	Central Nervous System Neoplasms	4.6%
262	Vascular Neoplasms	4.6%
263	Thymus Neoplasms	4.6%
264	Genital Neoplasms, Female	4.5%
265	Pancreatic Pseudocyst	4.5%
266	Lymphatic Metastasis	4.5%
267	Neoplasms, Unknown Primary	4.5%
268	Leukemic Infiltration	4.5%
269	Breast Neoplasms, Male	4.5%
270	Neoplasm Micrometastasis	4.5%
271	Triple Negative Breast Neoplasms	4.5%
272	Esophageal Neoplasms	4.5%
273	Limbic Encephalitis	4.4%
274	Denys-Drash Syndrome	4.4%
275	Fibromatosis, Aggressive	4.1%
276	Fibromatosis, Abdominal	4.1%
277	Lambert-Eaton Myasthenic Syndrome	4%
278	Testicular Neoplasms	4%
279	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	4%
280	Leukemia, Large Granular Lymphocytic	4%
281	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	4%
282	Lymphoma, T-Cell, Cutaneous	3.9%
283	Lymphoma, AIDS-Related	3.9%
284	Enteropathy-Associated T-Cell Lymphoma	3.9%
285	Primary Effusion Lymphoma	3.9%
286	Xeroderma Pigmentosum	3.9%
287	Adrenal Gland Neoplasms	3.9%
288	Gastrointestinal Neoplasms	3.9%
289	Genital Neoplasms, Male	3.9%
290	Liver neoplasms	3.9%
291	Uveal Neoplasms	3.9%
292	Urologic Neoplasms	3.8%
293	Sebaceous Gland Neoplasms	3.8%
294	Spinal Neoplasms	3.8%
295	Bone Marrow Neoplasms	3.8%
296	Polycystic Ovary Syndrome	3.7%
297	Leydig Cell Tumor	3.7%
298	Thyroid Nodule	3.7%
299	Opsoclonus-Myoclonus Syndrome	3.6%
300	Myelitis, Transverse	3.2%
301	Burkitt Lymphoma	3%
302	ovarian neoplasm	2.9%
303	Dupuytren Contracture	2.8%
304	Urticaria Pigmentosa	2.8%
305	Mycosis Fungoides	2.8%
306	Lymphomatoid Papulosis	2.8%
307	Plasmablastic lymphoma	2.8%
308	Nose Neoplasms	2.7%
309	Meningeal Neoplasms	2.6%
310	Pituitary Adenoma	2.5%
311	Pituitary Neoplasms	2.5%
312	Palatal Neoplasms	2.3%
313	Zollinger-Ellison syndrome	2.3%
314	Ear Neoplasms	2.2%
315	Eyelid Neoplasms	2.2%
316	Lung Neoplasms	2.2%
317	Pleural Neoplasms	2.2%
318	Cell Transformation, Viral	2.2%
319	Brain Neoplasms	2.2%
320	Salivary Gland Neoplasms	2.2%
321	Spinal Cord Neoplasms	2.2%
322	Tongue Neoplasms	2.2%
323	Uterine Neoplasms	2.1%
324	Vaginal Neoplasms	2.1%
325	Vulvar Neoplasms	2.1%
326	Uterine Cancer	2.1%
327	Fallopian Tube Neoplasms	2.1%
328	Sezary Syndrome	2.1%
329	Pharyngeal Neoplasms	1.9%
330	Central Nervous System Cysts	1.9%
331	Bile Duct Neoplasms	1.9%
332	gallbladder neoplasm	1.9%
333	Intestinal Neoplasms	1.9%
334	Penile Neoplasms	1.9%
335	Prostatic Neoplasms	1.9%
336	Stomach Neoplasms	1.9%
337	Polycythemia Vera	1.8%
338	Laryngeal neoplasm	1.7%
339	Bladder Neoplasm	1.6%
340	Kidney Neoplasm	1.6%
341	Ureteral Neoplasms	1.6%
342	Urethral Neoplasms	1.6%
343	Meningeal Carcinomatosis	1.6%
344	Bronchial Neoplasms	1.4%
345	Multiple Pulmonary Nodules	1.3%
346	Supratentorial Neoplasms	1.3%
347	Endometrial Neoplasms	1.3%
348	Hypopharyngeal Neoplasms	1.2%
349	Pleural Effusion, Malignant	1.2%
350	Hypopharyngeal Cancer	1.2%
351	Parotid Neoplasms	1.1%
352	Prostatic Neoplasms, Castration-Resistant	1.1%
353	Nelson Syndrome	1.1%
354	Cecal Neoplasms	1%
355	Duodenal Neoplasms	1%
356	Brain Stem Neoplasms	0.9%
357	Nasopharyngeal Neoplasms	0.9%
358	Colorectal Neoplasms	0.9%
359	Paranasal Sinus Neoplasms	0.8%
360	Tonsillar Neoplasms	0.8%
361	Cerebellar Neoplasms	0.8%
362	Choroid Plexus Papilloma	0.7%
363	Radicular Cyst	0.7%
364	Appendiceal Neoplasms	0.7%
365	Colonic Neoplasms	0.7%
366	Rectal Neoplasms	0.7%
367	Maxillary Sinus Neoplasms	0.6%
368	Anus Neoplasms	0.5%
369	Sigmoid Neoplasms	0.5%

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