MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Neoplasms, Second Primary

(UMLS:C0085183)

Definition:: Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause.
UMLS ID:: C0085183
MeSH ID:: D016609

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.692

Synonym(s)

Neoplasms, Second Primary

malignancy second

second malignancies

second malignancy

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Azathioprine	20026017	CTD
2	BEACOPP protocol	20026017	CTD
3	Epirubicin	19884644	CTD
4	Idarubicin	28973540	CTD
5	Ifosfamide	7596151	CTD
6	Mitoxantrone	19884644	CTD
7	Razoxane	17290056	CTD
8	fludarabine	20026017	CTD
9	wogonin	23872129	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Hamartoma	33.3%
2	Neoplasms, Hormone-Dependent	33.3%
3	Neoplasms, Multiple Primary	33.3%
4	Paraneoplastic Syndromes	33.3%
5	Precancerous Conditions	33.3%
6	Carcinoma 256, Walker	25.8%
7	Carcinoma, Ehrlich Tumor	25.3%
8	Dermoid Cyst	25.3%
9	Carcinoma, Lewis Lung	25.3%
10	Neoplasms, Neuroepithelial	24.1%
11	Gliomatosis cerebri	24.1%
12	Neuroectodermal Tumors	23.8%
13	Medulloblastoma	23.4%
14	Abdominal Neoplasms	23.1%
15	Erythroplasia	23.1%
16	Follicular cyst	23.1%
17	Head and Neck Neoplasms	23.1%
18	leukemia	23.1%
19	melanoma	23.1%
20	Mucocele	23.1%
21	Neoplasms, Germ Cell and Embryonal	23.1%
22	Neoplasms, Glandular and Epithelial	23.1%
23	Pilonidal Cyst	23.1%
24	Soft Tissue Neoplasms	23.1%
25	Thoracic Neoplasms	23.1%
26	Thyroglossal Cyst	23.1%
27	Synovial Cyst	23.1%
28	Germ Cell Cancer	23.1%
29	Aberrant Crypt Foci	23.1%
30	Carcinosarcoma	22.4%
31	Hemangiosarcoma	22.4%
32	Leukemia L1210	22.4%
33	Leukemia P388	22.4%
34	lymphangiosarcoma	22.4%
35	Acanthoma	22.4%
36	Adenoma, Acidophil	22%
37	Ganglioneuroma	22%
38	Glioma	22%
39	Malignant Glioma	22%
40	Sarcoma 180	21.6%
41	Carcinoid Tumor	21.5%
42	Neurilemmoma	21.5%
43	Hutchinson's Melanotic Freckle	21.5%
44	Melanoma, Amelanotic	21.5%
45	Melanoma, Experimental	21.1%
46	Cyst	21.1%
47	Neoplastic Processes	21.1%
48	Neoplastic Syndromes, Hereditary	21.1%
49	Pregnancy Complications, Neoplastic	21.1%
50	Astrocytoma	21%
51	Ependymoma	21%
52	oligodendroglioma	21%
53	Ganglioglioma	21%
54	gliosarcoma	21%
55	Anaplastic astrocytoma	21%
56	Anaplastic Oligodendroglioma	21%
57	Basal cell carcinoma	20.9%
58	Carcinoma, Papillary	20.9%
59	Squamous cell carcinoma	20.9%
60	Chondrosarcoma	20.9%
61	Craniopharyngioma	20.9%
62	Cystadenoma	20.9%
63	leiomyosarcoma	20.9%
64	liposarcoma	20.9%
65	Mesothelioma	20.9%
66	synovial sarcoma	20.9%
67	Neuroectodermal Tumor, Melanotic	20.9%
68	Angiomyolipoma	20.9%
69	Clear Cell Sarcoma of Soft Tissue	20.9%
70	Alveolar Soft Part Sarcoma	20.9%
71	Neuroendocrine Tumors	20.9%
72	Sarcoma, Myeloid	20.9%
73	Carcinoma, Basal Cell	20.9%
74	Malignant Carcinoid Syndrome	20.8%
75	Neoplasms, Experimental	20.5%
76	Glioblastoma	20.5%
77	Neuroblastoma	20.5%
78	Glioblastoma Multiforme	20.5%
79	Ganglioneuroblastoma	20.3%
80	Multiple Endocrine Neoplasia	20.2%
81	Cystadenocarcinoma	20.2%
82	Fibrosarcoma	20.2%
83	Osteosarcoma	20.2%
84	Mucoepidermoid Carcinoma	20.2%
85	Paraneoplastic Encephalomyelitis	20%
86	Adenofibroma	19.9%
87	Fibroadenoma	19.9%
88	Malignant Fibrous Histiocytoma	19.9%
89	Trophoblastic Neoplasms	19.6%
90	Bowen's Disease	19.5%
91	Paraganglioma	19.5%
92	Rhabdomyosarcoma	19.5%
93	Giant Cell Tumor of Bone	19.5%
94	Leukemia, Experimental	19.5%
95	Mammary Neoplasms, Experimental	19.5%
96	Meningioma	19.5%
97	Dermatofibrosarcoma	19.2%
98	Dermatofibrosarcoma Protuberans	19.2%
99	Pheochromocytoma	18.9%
100	Alveolar rhabdomyosarcoma	18.9%
101	Choriocarcinoma	18.6%
102	Carcinoma, Lobular	18.6%
103	Adenoma	18.5%
104	Ameloblastoma	18.5%
105	Angiokeratoma	18.5%
106	Carcinoma	18.5%
107	Chordoma	18.5%
108	Hemangioma	18.5%
109	hemangiopericytoma	18.5%
110	Lymphangioma	18.5%
111	Mesenchymoma	18.5%
112	Nevus	18.5%
113	Retroperitoneal Neoplasms	18.5%
114	Teratoma	18.5%
115	Hepatoblastoma	18.5%
116	Mixed Tumor, Mullerian	18.5%
117	Germinoma	18.5%
118	Teratocarcinoma	18.5%
119	Angiofibroma	18.5%
120	Sarcoma	18.5%
121	Epithelioma	18.5%
122	Sarcoma, Experimental	18.4%
123	Thymoma	16.5%
124	Carcinoid Heart Disease	16.5%
125	Multiple Endocrine Neoplasia Type 1	16.5%
126	Leukemia, Plasma Cell	16.4%
127	Adenocarcinoma	16.4%
128	Carcinoma in Situ	16.4%
129	Carcinoma, Transitional Cell	16.4%
130	Phyllodes Tumor	16.4%
131	Dysgerminoma	16.4%
132	Hemangioendothelioma	16.4%
133	Lipoma	16.4%
134	Myoma	16.4%
135	Myxoma	16.4%
136	Neuroma	16.4%
137	Papilloma	16.4%
138	Pseudomyxoma Peritonei	16.4%
139	Seminoma	16.4%
140	Papillomatosis	16.4%
141	Angiolipoma	16.4%
142	Myelolipoma	16.4%
143	Neoplasms, Bone Tissue	16.4%
144	Neoplasms, Fibrous Tissue	16.4%
145	Smooth Muscle Tumor	16.4%
146	Adenomatosis, Pulmonary	16.4%
147	Adenomatous Polyps	16.4%
148	Carcinoma, Large Cell	16.4%
149	Carcinoma, Small Cell	16.4%
150	Desmoplastic Small Round Cell Tumor	16.4%
151	Chondroma	16.4%
152	Enchondroma	16.4%
153	Digestive System Neoplasms	15.8%
154	Endocrine Gland Neoplasms	15.8%
155	Eye Neoplasms	15.8%
156	Nervous System Neoplasms	15.8%
157	Leukemia, Radiation-Induced	15.6%
158	Adenoid Cystic Carcinoma	15.3%
159	fibroma	15.3%
160	Fibromatosis	15.3%
161	Osteoblastoma	15.3%
162	Osteoma	15.3%
163	Rhabdomyoma	15.3%
164	Chondromatosis	15.3%
165	Adenocarcinoma, Clear Cell	15.3%
166	Cholangiocarcinoma	15.3%
167	Cervical Intraepithelial Neoplasia	15.3%
168	Hemangioblastoma	15.3%
169	Lymphoma, Extranodal NK-T-Cell	15.3%
170	Bone neoplasms	15%
171	Leukoplakia	15%
172	Lymphocele	15%
173	Pancreatic Cyst	15%
174	Skin Neoplasms	15%
175	Hematologic Neoplasms	15%
176	Neoplasms, Radiation-Induced	15%
177	Hydatidiform Mole	14.8%
178	Fibromatosis, Aggressive	14.8%
179	Fibromatosis, Abdominal	14.8%
180	Klatskin Tumor	14.8%
181	Retinoblastoma	14.8%
182	Barrett Esophagus	14.6%
183	Breast Cyst	14.6%
184	Histiocytic Disorders, Malignant	14.6%
185	Actinic keratosis	14.6%
186	Mediastinal Cyst	14.6%
187	Neoplasm Invasiveness	14.6%
188	Neoplasm Metastasis	14.6%
189	Neoplasm Recurrence, Local	14.6%
190	Parovarian Cyst	14.6%
191	Pericardial Cyst	14.6%
192	Splenic Neoplasms	14.6%
193	Thymic Cyst	14.6%
194	Carcinogenesis	14.6%
195	Myxoid cyst	14.6%
196	Metastasis	14.6%
197	Carcinoma, Pancreatic Ductal	14.5%
198	Parathyroid Neoplasms	14.3%
199	Peritoneal Neoplasms	14.3%
200	Thyroid Neoplasm	14.3%
201	Thyroid carcinoma	14.3%
202	Acoustic Neuroma	14%
203	Lymphomatoid Granulomatosis	13.9%
204	Neurofibrosarcoma	13.9%
205	Vipoma	13.8%
206	Composite Lymphoma	13.7%
207	Tracheal Neoplasms	13.5%
208	Leukoplakia, Oral	13.1%
209	Paraneoplastic Cerebellar Degeneration	13%
210	Basal Cell Nevus Syndrome	12.6%
211	Tuberous Sclerosis	12.5%
212	Optic Nerve Glioma	12.4%
213	Endometrial Stromal Sarcoma	12.4%
214	Thyroid Nodule	12.3%
215	Hepatocellular Adenoma	12.3%
216	Mouth Neoplasms	12.2%
217	Central Nervous System Neoplasms	12.2%
218	Vascular Neoplasms	12.2%
219	Thymus Neoplasms	12.2%
220	Lymphangioleiomyomatosis	12.2%
221	Liver Neoplasms, Experimental	12.1%
222	insulinoma	12.1%
223	Gastrinoma	11.9%
224	Glucagonoma	11.9%
225	Genital Neoplasms, Female	11.9%
226	Pancreatic Neoplasm	11.9%
227	Pancreatic Pseudocyst	11.9%
228	Plasmacytoma	11.9%
229	Malignant histiocytosis	11.8%
230	Lymphatic Metastasis	11.8%
231	Neoplasms, Unknown Primary	11.8%
232	Leukemic Infiltration	11.8%
233	Breast Neoplasms, Male	11.8%
234	Histiocytic sarcoma	11.8%
235	Neoplasm Micrometastasis	11.8%
236	Triple Negative Breast Neoplasms	11.8%
237	Nephroblastoma	11.4%
238	Esophageal Neoplasms	10.9%
239	Limbic Encephalitis	10.7%
240	Lymphoma	10.7%
241	Meningeal Neoplasms	10.6%
242	Corpus Luteum Cyst	10.6%
243	Ovarian Cysts	10.6%
244	Leukemia, Myelomonocytic, Chronic	10.5%
245	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	10.5%
246	Leydig Cell Tumor	10.3%
247	Prolactinoma	10.1%
248	Growth Hormone-Secreting Pituitary Adenoma	10.1%
249	Mastocytoma	9.9%
250	Meningeal Carcinomatosis	9.8%
251	Mastocytosis, Systemic	9.8%
252	Leukemia, Myeloid, Chronic-Phase	9.8%
253	Adenomatous Polyposis Coli	9.5%
254	Adrenocortical carcinoma	9.4%
255	Lambert-Eaton Myasthenic Syndrome	9.4%
256	Testicular Neoplasms	9.4%
257	Adrenal Gland Neoplasms	9.1%
258	Gastrointestinal Neoplasms	9.1%
259	Genital Neoplasms, Male	9.1%
260	Liver neoplasms	9.1%
261	Uveal Neoplasms	9.1%
262	Urologic Neoplasms	8.9%
263	Mesoblastic Nephroma	8.8%
264	Sebaceous Gland Neoplasms	8.8%
265	Spinal Neoplasms	8.8%
266	Bone Marrow Neoplasms	8.8%
267	Hodgkin Disease	8.6%
268	Lymphoma, Non-Hodgkin	8.6%
269	Choledochal Cyst	8.6%
270	Polycystic Ovary Syndrome	8.6%
271	granulosa cell tumor	8.6%
272	Carcinoma, Ovarian Epithelial	8.6%
273	Palatal Neoplasms	8.4%
274	Peutz-Jeghers Syndrome	8.3%
275	Opsoclonus-Myoclonus Syndrome	8.1%
276	Ear Neoplasms	8.1%
277	Eyelid Neoplasms	8.1%
278	Lung Neoplasms	8.1%
279	Pleural Neoplasms	8.1%
280	Renal Cell Carcinoma	8%
281	Papillary Renal Cell Carcinoma	8%
282	Mastocytosis	8%
283	Sturge-Weber Syndrome	8%
284	Cell Transformation, Viral	7.9%
285	Nose Neoplasms	7.9%
286	Carcinoma, Endometrioid	7.9%
287	Brain Neoplasms	7.8%
288	Salivary Gland Neoplasms	7.8%
289	Spinal Cord Neoplasms	7.8%
290	Tongue Neoplasms	7.8%
291	Gastrointestinal Stromal Tumors	7.8%
292	Hemangioma, Cavernous	7.8%
293	Leukemia, T-Cell	7.7%
294	Uterine Neoplasms	7.7%
295	Vaginal Neoplasms	7.7%
296	Vulvar Neoplasms	7.7%
297	Uterine Cancer	7.7%
298	Leukemia, B-Cell	7.7%
299	Fallopian Tube Neoplasms	7.7%
300	neurofibroma	7.7%
301	Lymphoma, Follicular	7.6%
302	T-Cell Lymphoma	7.6%
303	Mantle cell lymphoma	7.6%
304	Bronchial Neoplasms	7.5%
305	Multiple Pulmonary Nodules	7.4%
306	Dupuytren Contracture	7.3%
307	Supratentorial Neoplasms	7.2%
308	Endometrial Neoplasms	7.2%
309	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	7.2%
310	Leukemia, Large Granular Lymphocytic	7.2%
311	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	7.2%
312	Lymphoma, T-Cell, Cutaneous	7.1%
313	Lymphoma, AIDS-Related	7.1%
314	Enteropathy-Associated T-Cell Lymphoma	7.1%
315	Primary Effusion Lymphoma	7.1%
316	Nasopharyngeal carcinoma	7.1%
317	Myelitis, Transverse	7.1%
318	Urticaria Pigmentosa	7.1%
319	Brain Stem Neoplasms	6.9%
320	Mycosis Fungoides	6.9%
321	Lymphomatoid Papulosis	6.9%
322	Plasmablastic lymphoma	6.9%
323	Primary amyloidosis	6.9%
324	Denys-Drash Syndrome	6.8%
325	Choroid Plexus Papilloma	6.8%
326	Pituitary Adenoma	6.8%
327	Pituitary Neoplasms	6.8%
328	Pharyngeal Neoplasms	6.5%
329	Central Nervous System Cysts	6.3%
330	Bile Duct Neoplasms	6.2%
331	gallbladder neoplasm	6.2%
332	Intestinal Neoplasms	6.2%
333	Penile Neoplasms	6.2%
334	Prostatic Neoplasms	6.2%
335	Stomach Neoplasms	6.2%
336	Polycythemia Vera	6.1%
337	Hypopharyngeal Neoplasms	5.8%
338	Pleural Effusion, Malignant	5.8%
339	Hypopharyngeal Cancer	5.8%
340	ovarian neoplasm	5.7%
341	Parotid Neoplasms	5.7%
342	Prostatic Neoplasms, Castration-Resistant	5.7%
343	Nelson Syndrome	5.7%
344	Tonsillar Neoplasms	5.5%
345	Cerebellar Neoplasms	5.5%
346	Laryngeal neoplasm	5.4%
347	Bladder Neoplasm	5.1%
348	Kidney Neoplasm	5.1%
349	Ureteral Neoplasms	5.1%
350	Urethral Neoplasms	5.1%
351	Waldenstrom Macroglobulinemia	4.9%
352	Multiple Myeloma	4.9%
353	Cecal Neoplasms	4.7%
354	Duodenal Neoplasms	4.7%
355	Burkitt Lymphoma	4.7%
356	Sezary Syndrome	4.6%
357	Radicular Cyst	4.6%
358	Xeroderma Pigmentosum	4.6%
359	Appendiceal Neoplasms	4.5%
360	Colonic Neoplasms	4.5%
361	Rectal Neoplasms	4.5%
362	Zollinger-Ellison syndrome	4.2%
363	Nasopharyngeal Neoplasms	4.1%
364	Colorectal Neoplasms	4%
365	Anus Neoplasms	3.8%
366	Sigmoid Neoplasms	3.8%
367	Paranasal Sinus Neoplasms	3.6%
368	Maxillary Sinus Neoplasms	3.4%

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120234