MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Cervical Intraepithelial Neoplasia

(UMLS:C0206708)

Definition:: A malignancy arising in uterine cervical epithelium and confined thereto, representing a continuum of histological changes ranging from well-differentiated CIN 1 (formerly, mild dysplasia) to severe dysplasia/carcinoma in situ, CIN 3. The lesion arises at the squamocolumnar cell junction at the transformation zone of the endocervical canal, with a variable tendency to develop invasive epidermoid carcinoma, a tendency that is enhanced by concomitant human papillomaviral infection. (Segen, Dictionary of Modern Medicine, 1992)
UMLS ID:: C0206708
MeSH ID:: D018290

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.470.200.240.250

Synonym(s)

Cervical Intraepithelial Neoplasia

CIN

CIN - Cervical intraepithelial neoplasia

Cervical Dysplasia

Cervical intraepith. neoplasia

Cervical intraepithelial neoplasia

Cervical intraepithelial neoplasia (CIN)

Cervix Intraepithelial Neoplasia

Cervix Uteri Intraepithelial Neoplasia

10.

Intraepithelial Neoplasia of Cervix

11.

Intraepithelial Neoplasia of Cervix Uteri

12.

Intraepithelial Neoplasia of Uterine Cervix

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Fenretinide	16154183	CTD
2	Nicotine	20190800	CTD
3	Tretinoin	16129372	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Adenocarcinoma	36%
2	Carcinoma, Transitional Cell	36%
3	Carcinoma, Large Cell	36%
4	Carcinoma, Small Cell	36%
5	Basal cell carcinoma	35.3%
6	Carcinoma, Papillary	35.3%
7	Squamous cell carcinoma	35.3%
8	Carcinoma, Basal Cell	35.3%
9	Carcinoma, Ehrlich Tumor	29.8%
10	Carcinoma, Lewis Lung	29.8%
11	Adenoma	28.5%
12	Cystadenocarcinoma	27.1%
13	Mucoepidermoid Carcinoma	27.1%
14	Adenoid Cystic Carcinoma	23.8%
15	Adenocarcinoma, Clear Cell	23.8%
16	Cholangiocarcinoma	23.8%
17	Bowen's Disease	23.3%
18	leukemia	22.7%
19	Neoplasms, Germ Cell and Embryonal	22.7%
20	Germ Cell Cancer	22.7%
21	Cystadenoma	22.5%
22	Mesothelioma	22.5%
23	Neoplasms, Neuroepithelial	21.5%
24	Gliomatosis cerebri	21.5%
25	Carcinoma, Lobular	18.1%
26	Klatskin Tumor	17.8%
27	Papilloma	16.8%
28	Pseudomyxoma Peritonei	16.8%
29	Papillomatosis	16.8%
30	Adenomatosis, Pulmonary	16.8%
31	Adenomatous Polyps	16.8%
32	Carcinoid Tumor	16.7%
33	Neuroectodermal Tumors	16.4%
34	Hamartoma	15.3%
35	Neoplasms, Hormone-Dependent	15.3%
36	Neoplasms, Multiple Primary	15.3%
37	Paraneoplastic Syndromes	15.3%
38	Precancerous Conditions	15.3%
39	Neoplasms, Second Primary	15.3%
40	Histiocytic Disorders, Malignant	15.1%
41	Choriocarcinoma	14.2%
42	Acanthoma	14.1%
43	Adenofibroma	13.5%
44	Fibroadenoma	13.5%
45	Adenoma, Acidophil	13.1%
46	Ganglioneuroma	13.1%
47	Glioma	13.1%
48	Malignant Glioma	13.1%
49	Carcinosarcoma	13%
50	Hemangiosarcoma	13%
51	lymphangiosarcoma	13%
52	Malignant Carcinoid Syndrome	12.4%
53	Ameloblastoma	12.2%
54	Angiokeratoma	12.2%
55	Chordoma	12.2%
56	Hemangioma	12.2%
57	hemangiopericytoma	12.2%
58	Lymphangioma	12.2%
59	Mesenchymoma	12.2%
60	Nevus	12.2%
61	Teratoma	12.2%
62	Hepatoblastoma	12.2%
63	Mixed Tumor, Mullerian	12.2%
64	Germinoma	12.2%
65	Teratocarcinoma	12.2%
66	Angiofibroma	12.2%
67	Sarcoma	12.2%
68	Lymphoma	11.3%
69	Carcinoma, Ovarian Epithelial	11%
70	melanoma	10.8%
71	Meningioma	10.4%
72	Medulloblastoma	10.4%
73	Cyst	10.2%
74	Neoplastic Processes	10.2%
75	Neoplastic Syndromes, Hereditary	10.2%
76	Pregnancy Complications, Neoplastic	10.2%
77	Trophoblastic Neoplasms	10%
78	Leukemia, Experimental	10%
79	Dermoid Cyst	9.9%
80	Neoplasms, Experimental	9.9%
81	Carcinoma 256, Walker	9.8%
82	Composite Lymphoma	9.8%
83	Leukemia, Plasma Cell	9.7%
84	Chondrosarcoma	9.6%
85	Craniopharyngioma	9.6%
86	leiomyosarcoma	9.6%
87	liposarcoma	9.6%
88	synovial sarcoma	9.6%
89	Neuroectodermal Tumor, Melanotic	9.6%
90	Angiomyolipoma	9.6%
91	Clear Cell Sarcoma of Soft Tissue	9.6%
92	Alveolar Soft Part Sarcoma	9.6%
93	Neuroendocrine Tumors	9.6%
94	Sarcoma, Myeloid	9.6%
95	Nasopharyngeal carcinoma	9.3%
96	Astrocytoma	9.1%
97	Ependymoma	9.1%
98	oligodendroglioma	9.1%
99	Ganglioglioma	9.1%
100	gliosarcoma	9.1%
101	Anaplastic astrocytoma	9.1%
102	Anaplastic Oligodendroglioma	9.1%
103	Basal Cell Nevus Syndrome	9%
104	Carcinoma, Pancreatic Ductal	8.6%
105	Adrenocortical carcinoma	8.5%
106	Carcinoid Heart Disease	8.5%
107	Plasmacytoma	8.2%
108	Malignant histiocytosis	8.1%
109	Histiocytic sarcoma	8.1%
110	Leukemia, Radiation-Induced	8.1%
111	Fibrosarcoma	8%
112	Osteosarcoma	8%
113	Hepatocellular Adenoma	7.8%
114	Leukemia L1210	7.6%
115	Leukemia P388	7.6%
116	Abdominal Neoplasms	7.6%
117	Erythroplasia	7.6%
118	Follicular cyst	7.6%
119	Head and Neck Neoplasms	7.6%
120	Mucocele	7.6%
121	Pilonidal Cyst	7.6%
122	Soft Tissue Neoplasms	7.6%
123	Thoracic Neoplasms	7.6%
124	Thyroglossal Cyst	7.6%
125	Synovial Cyst	7.6%
126	Aberrant Crypt Foci	7.6%
127	Neoplasms, Radiation-Induced	7.4%
128	Sarcoma, Experimental	7.4%
129	Retinoblastoma	7.4%
130	Thymoma	7.3%
131	Melanoma, Experimental	7.3%
132	Renal Cell Carcinoma	7.3%
133	Papillary Renal Cell Carcinoma	7.3%
134	Phyllodes Tumor	7.2%
135	Dysgerminoma	7.2%
136	Hemangioendothelioma	7.2%
137	Lipoma	7.2%
138	Myoma	7.2%
139	Myxoma	7.2%
140	Neuroma	7.2%
141	Seminoma	7.2%
142	Angiolipoma	7.2%
143	Myelolipoma	7.2%
144	Neoplasms, Bone Tissue	7.2%
145	Neoplasms, Fibrous Tissue	7.2%
146	Smooth Muscle Tumor	7.2%
147	Desmoplastic Small Round Cell Tumor	7.2%
148	Chondroma	7.2%
149	Enchondroma	7.2%
150	Malignant Fibrous Histiocytoma	7.2%
151	Neurilemmoma	7.1%
152	Hutchinson's Melanotic Freckle	7.1%
153	Melanoma, Amelanotic	7.1%
154	Carcinoma, Endometrioid	7.1%
155	Glioblastoma	7.1%
156	Neuroblastoma	7.1%
157	Glioblastoma Multiforme	7.1%
158	Endometrial Stromal Sarcoma	6.7%
159	Multiple Endocrine Neoplasia	6.6%
160	Prolactinoma	6.5%
161	Growth Hormone-Secreting Pituitary Adenoma	6.5%
162	Paraganglioma	6.3%
163	Rhabdomyosarcoma	6.3%
164	Giant Cell Tumor of Bone	6.3%
165	Vipoma	6.2%
166	Ganglioneuroblastoma	6.1%
167	Hodgkin Disease	6.1%
168	Lymphoma, Non-Hodgkin	6.1%
169	Gastrinoma	6%
170	Glucagonoma	6%
171	Paraneoplastic Encephalomyelitis	6%
172	Sarcoma 180	5.9%
173	Mammary Neoplasms, Experimental	5.8%
174	Lymphangioleiomyomatosis	5.8%
175	Dermatofibrosarcoma	5.5%
176	Dermatofibrosarcoma Protuberans	5.5%
177	Digestive System Neoplasms	5.4%
178	Endocrine Gland Neoplasms	5.4%
179	Eye Neoplasms	5.4%
180	Nervous System Neoplasms	5.4%
181	Bone neoplasms	5.1%
182	Leukoplakia	5.1%
183	Lymphocele	5.1%
184	Pancreatic Cyst	5.1%
185	Skin Neoplasms	5.1%
186	Hematologic Neoplasms	5.1%
187	Barrett Esophagus	5%
188	Breast Cyst	5%
189	Actinic keratosis	5%
190	Mediastinal Cyst	5%
191	Neoplasm Invasiveness	5%
192	Neoplasm Metastasis	5%
193	Neoplasm Recurrence, Local	5%
194	Parovarian Cyst	5%
195	Pericardial Cyst	5%
196	Splenic Neoplasms	5%
197	Thymic Cyst	5%
198	Carcinogenesis	5%
199	Myxoid cyst	5%
200	Metastasis	5%
201	Primary amyloidosis	4.9%
202	Lymphomatoid Granulomatosis	4.9%
203	Leukemia, Myelomonocytic, Chronic	4.8%
204	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	4.8%
205	fibroma	4.8%
206	Fibromatosis	4.8%
207	Osteoblastoma	4.8%
208	Osteoma	4.8%
209	Rhabdomyoma	4.8%
210	Chondromatosis	4.8%
211	Hemangioblastoma	4.8%
212	Lymphoma, Extranodal NK-T-Cell	4.8%
213	Pheochromocytoma	4.7%
214	Alveolar rhabdomyosarcoma	4.7%
215	Nephroblastoma	4.7%
216	Tuberous Sclerosis	4.6%
217	Neurofibrosarcoma	4.4%
218	insulinoma	4.1%
219	Retroperitoneal Neoplasms	4.1%
220	Adenomatous Polyposis Coli	4%
221	Mesoblastic Nephroma	3.9%
222	Optic Nerve Glioma	3.8%
223	Mastocytosis	3.7%
224	Sturge-Weber Syndrome	3.7%
225	Corpus Luteum Cyst	3.7%
226	Ovarian Cysts	3.7%
227	Gastrointestinal Stromal Tumors	3.7%
228	Hemangioma, Cavernous	3.6%
229	Leukemia, T-Cell	3.6%
230	Leukemia, B-Cell	3.6%
231	neurofibroma	3.6%
232	Hydatidiform Mole	3.6%
233	Lymphoma, Follicular	3.6%
234	T-Cell Lymphoma	3.6%
235	Mantle cell lymphoma	3.6%
236	Fibromatosis, Aggressive	3.6%
237	Fibromatosis, Abdominal	3.6%
238	Multiple Endocrine Neoplasia Type 1	3.5%
239	Waldenstrom Macroglobulinemia	3.5%
240	Multiple Myeloma	3.5%
241	Parathyroid Neoplasms	3.4%
242	Peritoneal Neoplasms	3.4%
243	Thyroid Neoplasm	3.4%
244	Thyroid carcinoma	3.4%
245	Liver Neoplasms, Experimental	3.3%
246	Mastocytoma	3.2%
247	Mastocytosis, Systemic	3.2%
248	Leukemia, Myeloid, Chronic-Phase	3.2%
249	Choledochal Cyst	3.1%
250	Acoustic Neuroma	3%
251	Peutz-Jeghers Syndrome	3%
252	Pancreatic Neoplasm	2.8%
253	Mouth Neoplasms	2.8%
254	Central Nervous System Neoplasms	2.8%
255	Vascular Neoplasms	2.8%
256	Thymus Neoplasms	2.8%
257	granulosa cell tumor	2.8%
258	Genital Neoplasms, Female	2.7%
259	Pancreatic Pseudocyst	2.7%
260	Lymphatic Metastasis	2.7%
261	Neoplasms, Unknown Primary	2.7%
262	Leukemic Infiltration	2.7%
263	Breast Neoplasms, Male	2.7%
264	Neoplasm Micrometastasis	2.7%
265	Triple Negative Breast Neoplasms	2.7%
266	Tracheal Neoplasms	2.7%
267	Leukoplakia, Oral	2.6%
268	Paraneoplastic Cerebellar Degeneration	2.6%
269	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	2.4%
270	Leukemia, Large Granular Lymphocytic	2.4%
271	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	2.4%
272	Lymphoma, T-Cell, Cutaneous	2.4%
273	Lymphoma, AIDS-Related	2.4%
274	Enteropathy-Associated T-Cell Lymphoma	2.4%
275	Primary Effusion Lymphoma	2.4%
276	Esophageal Neoplasms	2.2%
277	Limbic Encephalitis	2.2%
278	Adrenal Gland Neoplasms	2.1%
279	Gastrointestinal Neoplasms	2.1%
280	Genital Neoplasms, Male	2.1%
281	Liver neoplasms	2.1%
282	Uveal Neoplasms	2.1%
283	Urologic Neoplasms	2.1%
284	Sebaceous Gland Neoplasms	2.1%
285	Spinal Neoplasms	2.1%
286	Bone Marrow Neoplasms	2.1%
287	Polycystic Ovary Syndrome	2%
288	Thyroid Nodule	2%
289	Denys-Drash Syndrome	1.9%
290	Lambert-Eaton Myasthenic Syndrome	1.9%
291	Testicular Neoplasms	1.9%
292	Leydig Cell Tumor	1.9%
293	Dupuytren Contracture	1.9%
294	Urticaria Pigmentosa	1.8%
295	Mycosis Fungoides	1.8%
296	Lymphomatoid Papulosis	1.8%
297	Plasmablastic lymphoma	1.8%
298	Xeroderma Pigmentosum	1.7%
299	Opsoclonus-Myoclonus Syndrome	1.7%
300	Meningeal Neoplasms	1.6%
301	Burkitt Lymphoma	1.6%
302	Myelitis, Transverse	1.5%
303	ovarian neoplasm	1.4%
304	Nose Neoplasms	1.3%
305	Ear Neoplasms	1.3%
306	Eyelid Neoplasms	1.3%
307	Lung Neoplasms	1.3%
308	Pleural Neoplasms	1.3%
309	Cell Transformation, Viral	1.2%
310	Brain Neoplasms	1.2%
311	Salivary Gland Neoplasms	1.2%
312	Spinal Cord Neoplasms	1.2%
313	Tongue Neoplasms	1.2%
314	Uterine Neoplasms	1.2%
315	Vaginal Neoplasms	1.2%
316	Vulvar Neoplasms	1.2%
317	Uterine Cancer	1.2%
318	Sezary Syndrome	1.2%
319	Fallopian Tube Neoplasms	1.2%
320	Palatal Neoplasms	1.2%
321	Pituitary Adenoma	1.1%
322	Pituitary Neoplasms	1.1%
323	Meningeal Carcinomatosis	1.1%
324	Zollinger-Ellison syndrome	1%
325	Pharyngeal Neoplasms	1%
326	Central Nervous System Cysts	1%
327	Bile Duct Neoplasms	1%
328	gallbladder neoplasm	1%
329	Intestinal Neoplasms	1%
330	Penile Neoplasms	1%
331	Prostatic Neoplasms	1%
332	Stomach Neoplasms	1%
333	Polycythemia Vera	1%
334	Laryngeal neoplasm	0.9%
335	Bronchial Neoplasms	0.8%
336	Bladder Neoplasm	0.8%
337	Kidney Neoplasm	0.8%
338	Ureteral Neoplasms	0.8%
339	Urethral Neoplasms	0.8%
340	Multiple Pulmonary Nodules	0.8%
341	Supratentorial Neoplasms	0.8%
342	Endometrial Neoplasms	0.8%
343	Hypopharyngeal Neoplasms	0.7%
344	Pleural Effusion, Malignant	0.7%
345	Hypopharyngeal Cancer	0.7%
346	Parotid Neoplasms	0.6%
347	Prostatic Neoplasms, Castration-Resistant	0.6%
348	Nelson Syndrome	0.6%
349	Brain Stem Neoplasms	0.6%
350	Cecal Neoplasms	0.5%
351	Duodenal Neoplasms	0.5%
352	Choroid Plexus Papilloma	0.5%
353	Tonsillar Neoplasms	0.5%
354	Cerebellar Neoplasms	0.5%
355	Nasopharyngeal Neoplasms	0.5%
356	Colorectal Neoplasms	0.5%
357	Paranasal Sinus Neoplasms	0.4%
358	Radicular Cyst	0.4%
359	Appendiceal Neoplasms	0.4%
360	Colonic Neoplasms	0.4%
361	Rectal Neoplasms	0.4%
362	Maxillary Sinus Neoplasms	0.3%
363	Anus Neoplasms	0.3%
364	Sigmoid Neoplasms	0.3%

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120262