MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Fibrosarcoma

(UMLS:C0016057)

Definition:: A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed)
UMLS ID:: C0016057
MeSH ID:: D005354

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.450.565.590.350|C04.557.450.795.350

Synonym(s)

Fibrosarcoma

FIBROSARCOMA

FIBROSARCOMA, MALIGNANT

Fibrosarcoma (excluding infantile fibrosarcoma)

Fibrosarcoma - not infantile

Fibrosarcoma NOS

Fibrosarcoma, NOS

Malignant Fibromatous Neoplasm

[M]Fibrosarcoma NOS

10.

fibrosarcoma

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Imatinib Mesylate	FAERS: 4		US FAERS
2	Cabergoline	FAERS: 2		US FAERS
3	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	FAERS: 1		US FAERS
4	Glatiramer Acetate	FAERS: 1		US FAERS
5	Melphalan	FAERS: 1		US FAERS
6	Tacrolimus	FAERS: 1		US FAERS
7	1,8-dinitropyrene		3023884 4075282	CTD
8	2-nitrotoluene		12087420	CTD
9	Dactinomycin			OFFSIDES
10	Dexamethasone		15990687	CTD
11	Dipyrone			OFFSIDES
12	Indomethacin		10962813	CTD
13	Iodoacetic Acid		26327680	CTD
14	Methylcholanthrene		View details 10626785 10962813 12549624 14633661 23548910	CTD
15	Methylnitrosourea		11555667	CTD
16	Nelfinavir			OFFSIDES
17	Saquinavir			OFFSIDES
18	Tenofovir			OFFSIDES
19	Valacyclovir			OFFSIDES
20	Zalcitabine			OFFSIDES
21	Zidovudine			OFFSIDES
22	abacavir			OFFSIDES
23	dibenzo(a,h)pyrene		21863085	CTD
24	dibenzo(a,i)pyrene		21863085	CTD
25	dibenzo(a,l)pyrene		21863085	CTD
26	mangiferin		8957579	CTD
27	midostaurin	Canada Vigilance: 1		Canada Vigilance
28	naveglitazar		19700659	CTD
29	nickel subsulfide		14971660	CTD
30	tesaglitazar		17468185 21270424	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Chondrosarcoma	61.8%
2	synovial sarcoma	61.8%
3	Clear Cell Sarcoma of Soft Tissue	61.8%
4	Malignant Fibrous Histiocytoma	57.9%
5	Osteosarcoma	52.8%
6	leiomyosarcoma	52.2%
7	liposarcoma	52.2%
8	Alveolar Soft Part Sarcoma	52.2%
9	Carcinosarcoma	46.2%
10	Hemangiosarcoma	46.2%
11	lymphangiosarcoma	46.2%
12	fibroma	44.1%
13	Fibromatosis	44.1%
14	Phyllodes Tumor	43.3%
15	Desmoplastic Small Round Cell Tumor	43.3%
16	Sarcoma, Myeloid	41%
17	Giant Cell Tumor of Bone	40.6%
18	Angiomyolipoma	39.4%
19	Myxoma	39%
20	Neoplasms, Bone Tissue	39%
21	Chondroma	39%
22	Enchondroma	39%
23	Rhabdomyosarcoma	37.5%
24	Fibromatosis, Aggressive	34%
25	Fibromatosis, Abdominal	34%
26	Adenofibroma	33.9%
27	Fibroadenoma	33.9%
28	Sarcoma, Experimental	32.8%
29	Carcinoma 256, Walker	32.4%
30	leukemia	31.5%
31	Neoplasms, Germ Cell and Embryonal	31.5%
32	Neoplasms, Glandular and Epithelial	31.5%
33	Germ Cell Cancer	31.5%
34	Alveolar rhabdomyosarcoma	30.2%
35	Sarcoma 180	28.2%
36	Osteoblastoma	27.1%
37	Osteoma	27.1%
38	Chondromatosis	27.1%
39	Neuroectodermal Tumors	26.9%
40	Lipoma	26.2%
41	Myoma	26.2%
42	Angiolipoma	26.2%
43	Myelolipoma	26.2%
44	Smooth Muscle Tumor	26.2%
45	Endometrial Stromal Sarcoma	24.5%
46	Neoplasms, Neuroepithelial	24.3%
47	Gliomatosis cerebri	24.3%
48	Mastocytosis	24.1%
49	Gastrointestinal Stromal Tumors	23.8%
50	Histiocytic Disorders, Malignant	23.7%
51	Dupuytren Contracture	21%
52	Mastocytoma	20.6%
53	Mastocytosis, Systemic	20.4%
54	melanoma	20.3%
55	Hamartoma	20.2%
56	Neoplasms, Hormone-Dependent	20.2%
57	Neoplasms, Multiple Primary	20.2%
58	Paraneoplastic Syndromes	20.2%
59	Precancerous Conditions	20.2%
60	Neoplasms, Second Primary	20.2%
61	Meningioma	19.2%
62	Lymphoma	18.9%
63	Sarcoma	18.9%
64	Lymphangioleiomyomatosis	18.8%
65	Rhabdomyoma	18.6%
66	Composite Lymphoma	17.9%
67	Adenoma	17.8%
68	Ameloblastoma	17.8%
69	Angiokeratoma	17.8%
70	Carcinoma	17.8%
71	Chordoma	17.8%
72	Hemangioma	17.8%
73	hemangiopericytoma	17.8%
74	Lymphangioma	17.8%
75	Mesenchymoma	17.8%
76	Nevus	17.8%
77	Teratoma	17.8%
78	Hepatoblastoma	17.8%
79	Mixed Tumor, Mullerian	17.8%
80	Germinoma	17.8%
81	Teratocarcinoma	17.8%
82	Angiofibroma	17.8%
83	Epithelioma	17.8%
84	Leukemia, Plasma Cell	17.5%
85	Trophoblastic Neoplasms	17.3%
86	Leukemia, Experimental	17.2%
87	Basal cell carcinoma	16.9%
88	Carcinoma, Papillary	16.9%
89	Squamous cell carcinoma	16.9%
90	Craniopharyngioma	16.9%
91	Cystadenoma	16.9%
92	Mesothelioma	16.9%
93	Neuroectodermal Tumor, Melanotic	16.9%
94	Neuroendocrine Tumors	16.9%
95	Carcinoma, Basal Cell	16.9%
96	Fibrosarcoma	16.8%
97	Carcinoma, Ehrlich Tumor	16.5%
98	Dermoid Cyst	16.5%
99	Carcinoma, Lewis Lung	16.5%
100	Adenoma, Acidophil	16.3%
101	Ganglioneuroma	16.3%
102	Glioma	16.3%
103	Malignant Glioma	16.3%
104	Medulloblastoma	15.4%
105	Cyst	15.3%
106	Neoplastic Processes	15.3%
107	Neoplastic Syndromes, Hereditary	15.3%
108	Pregnancy Complications, Neoplastic	15.3%
109	Neoplasms, Experimental	15%
110	Neoplasms, Fibrous Tissue	15%
111	Melanoma, Experimental	14.8%
112	Leukemia, Radiation-Induced	14.5%
113	Cystadenocarcinoma	14.4%
114	Mucoepidermoid Carcinoma	14.4%
115	Carcinoid Tumor	14.3%
116	Neurilemmoma	14.3%
117	Hutchinson's Melanotic Freckle	14.3%
118	Melanoma, Amelanotic	14.3%
119	Plasmacytoma	13.5%
120	Malignant histiocytosis	13.4%
121	Histiocytic sarcoma	13.4%
122	Thymoma	13%
123	Leukemia L1210	13%
124	Leukemia P388	13%
125	Acanthoma	13%
126	Urticaria Pigmentosa	12.9%
127	Choriocarcinoma	12.6%
128	Carcinoma, Lobular	12.6%
129	Dermatofibrosarcoma	12.5%
130	Dermatofibrosarcoma Protuberans	12.5%
131	Astrocytoma	12.4%
132	Ependymoma	12.4%
133	oligodendroglioma	12.4%
134	Ganglioglioma	12.4%
135	gliosarcoma	12.4%
136	Anaplastic astrocytoma	12.4%
137	Anaplastic Oligodendroglioma	12.4%
138	Neoplasms, Radiation-Induced	12%
139	Bowen's Disease	12%
140	Paraganglioma	12%
141	Multiple Endocrine Neoplasia	11.9%
142	Malignant Carcinoid Syndrome	11.4%
143	Adenocarcinoma	11.2%
144	Carcinoma in Situ	11.2%
145	Carcinoma, Transitional Cell	11.2%
146	Dysgerminoma	11.2%
147	Hemangioendothelioma	11.2%
148	Neuroma	11.2%
149	Papilloma	11.2%
150	Pseudomyxoma Peritonei	11.2%
151	Seminoma	11.2%
152	Papillomatosis	11.2%
153	Adenomatosis, Pulmonary	11.2%
154	Adenomatous Polyps	11.2%
155	Carcinoma, Large Cell	11.2%
156	Carcinoma, Small Cell	11.2%
157	Hodgkin Disease	10.7%
158	Lymphoma, Non-Hodgkin	10.7%
159	Neurofibrosarcoma	10.5%
160	Retinoblastoma	10.5%
161	Abdominal Neoplasms	10.5%
162	Erythroplasia	10.5%
163	Follicular cyst	10.5%
164	Head and Neck Neoplasms	10.5%
165	Mucocele	10.5%
166	Pilonidal Cyst	10.5%
167	Soft Tissue Neoplasms	10.5%
168	Thoracic Neoplasms	10.5%
169	Thyroglossal Cyst	10.5%
170	Synovial Cyst	10.5%
171	Aberrant Crypt Foci	10.5%
172	Glioblastoma	10.4%
173	Neuroblastoma	10.4%
174	Glioblastoma Multiforme	10.4%
175	Paraneoplastic Encephalomyelitis	10.1%
176	Mammary Neoplasms, Experimental	9.9%
177	Pheochromocytoma	9.5%
178	Ganglioneuroblastoma	9.5%
179	Nephroblastoma	9.3%
180	Lymphomatoid Granulomatosis	9.2%
181	Primary amyloidosis	9%
182	Tuberous Sclerosis	8.7%
183	Carcinoid Heart Disease	8.5%
184	Leukemia, Myelomonocytic, Chronic	8.4%
185	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	8.4%
186	Digestive System Neoplasms	8.3%
187	Endocrine Gland Neoplasms	8.3%
188	Eye Neoplasms	8.3%
189	Nervous System Neoplasms	8.3%
190	Bone neoplasms	8%
191	Leukoplakia	8%
192	Lymphocele	8%
193	Pancreatic Cyst	8%
194	Skin Neoplasms	8%
195	Hematologic Neoplasms	8%
196	Basal Cell Nevus Syndrome	8%
197	Adenoid Cystic Carcinoma	8%
198	Adenocarcinoma, Clear Cell	8%
199	Cholangiocarcinoma	8%
200	Cervical Intraepithelial Neoplasia	8%
201	Hemangioblastoma	8%
202	Lymphoma, Extranodal NK-T-Cell	8%
203	Barrett Esophagus	7.9%
204	Breast Cyst	7.9%
205	Actinic keratosis	7.9%
206	Mediastinal Cyst	7.9%
207	Neoplasm Invasiveness	7.9%
208	Neoplasm Metastasis	7.9%
209	Neoplasm Recurrence, Local	7.9%
210	Parovarian Cyst	7.9%
211	Pericardial Cyst	7.9%
212	Splenic Neoplasms	7.9%
213	Thymic Cyst	7.9%
214	Carcinogenesis	7.9%
215	Myxoid cyst	7.9%
216	Metastasis	7.9%
217	Mesoblastic Nephroma	7.6%
218	Hepatocellular Adenoma	7.6%
219	Carcinoma, Pancreatic Ductal	7.4%
220	Acoustic Neuroma	7.1%
221	Hydatidiform Mole	7%
222	Sturge-Weber Syndrome	6.9%
223	Hemangioma, Cavernous	6.8%
224	Multiple Endocrine Neoplasia Type 1	6.8%
225	Leukemia, T-Cell	6.8%
226	Leukemia, B-Cell	6.8%
227	Waldenstrom Macroglobulinemia	6.7%
228	Multiple Myeloma	6.7%
229	neurofibroma	6.7%
230	Lymphoma, Follicular	6.7%
231	T-Cell Lymphoma	6.7%
232	Mantle cell lymphoma	6.7%
233	Prolactinoma	6.5%
234	Growth Hormone-Secreting Pituitary Adenoma	6.5%
235	Optic Nerve Glioma	6.4%
236	Klatskin Tumor	6.4%
237	Corpus Luteum Cyst	6.2%
238	Ovarian Cysts	6.2%
239	Parathyroid Neoplasms	6.2%
240	Peritoneal Neoplasms	6.2%
241	Thyroid Neoplasm	6.2%
242	Thyroid carcinoma	6.2%
243	Liver Neoplasms, Experimental	6.1%
244	Vipoma	6%
245	Leukemia, Myeloid, Chronic-Phase	6%
246	Retroperitoneal Neoplasms	5.9%
247	granulosa cell tumor	5.6%
248	Carcinoma, Ovarian Epithelial	5.6%
249	Adenomatous Polyposis Coli	5.6%
250	Pancreatic Neoplasm	5.3%
251	Choledochal Cyst	5.3%
252	Peutz-Jeghers Syndrome	5.2%
253	Tracheal Neoplasms	5%
254	insulinoma	5%
255	Leukoplakia, Oral	4.9%
256	Paraneoplastic Cerebellar Degeneration	4.9%
257	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	4.8%
258	Leukemia, Large Granular Lymphocytic	4.8%
259	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	4.8%
260	Lymphoma, T-Cell, Cutaneous	4.8%
261	Lymphoma, AIDS-Related	4.8%
262	Enteropathy-Associated T-Cell Lymphoma	4.8%
263	Primary Effusion Lymphoma	4.8%
264	Adrenocortical carcinoma	4.6%
265	Mouth Neoplasms	4.6%
266	Central Nervous System Neoplasms	4.6%
267	Vascular Neoplasms	4.6%
268	Thymus Neoplasms	4.6%
269	Genital Neoplasms, Female	4.5%
270	Pancreatic Pseudocyst	4.5%
271	Nasopharyngeal carcinoma	4.5%
272	Lymphatic Metastasis	4.5%
273	Neoplasms, Unknown Primary	4.5%
274	Leukemic Infiltration	4.5%
275	Breast Neoplasms, Male	4.5%
276	Neoplasm Micrometastasis	4.5%
277	Triple Negative Breast Neoplasms	4.5%
278	Gastrinoma	4.4%
279	Glucagonoma	4.4%
280	Leydig Cell Tumor	4.2%
281	Esophageal Neoplasms	4.2%
282	Limbic Encephalitis	4.2%
283	Denys-Drash Syndrome	4.1%
284	Renal Cell Carcinoma	4%
285	Papillary Renal Cell Carcinoma	4%
286	Mycosis Fungoides	3.8%
287	Lymphomatoid Papulosis	3.8%
288	Plasmablastic lymphoma	3.8%
289	Thyroid Nodule	3.8%
290	Carcinoma, Endometrioid	3.8%
291	Lambert-Eaton Myasthenic Syndrome	3.7%
292	Testicular Neoplasms	3.7%
293	Adrenal Gland Neoplasms	3.7%
294	Gastrointestinal Neoplasms	3.7%
295	Genital Neoplasms, Male	3.7%
296	Liver neoplasms	3.7%
297	Uveal Neoplasms	3.7%
298	Urologic Neoplasms	3.7%
299	Sebaceous Gland Neoplasms	3.6%
300	Spinal Neoplasms	3.6%
301	Bone Marrow Neoplasms	3.6%
302	Polycystic Ovary Syndrome	3.5%
303	Burkitt Lymphoma	3.4%
304	Opsoclonus-Myoclonus Syndrome	3.3%
305	Xeroderma Pigmentosum	3.2%
306	Myelitis, Transverse	2.9%
307	Meningeal Neoplasms	2.8%
308	Sezary Syndrome	2.8%
309	Nose Neoplasms	2.6%
310	ovarian neoplasm	2.6%
311	Palatal Neoplasms	2.4%
312	Pituitary Adenoma	2.4%
313	Pituitary Neoplasms	2.4%
314	Ear Neoplasms	2.3%
315	Eyelid Neoplasms	2.3%
316	Lung Neoplasms	2.3%
317	Pleural Neoplasms	2.3%
318	Cell Transformation, Viral	2.3%
319	Brain Neoplasms	2.3%
320	Salivary Gland Neoplasms	2.3%
321	Spinal Cord Neoplasms	2.3%
322	Tongue Neoplasms	2.3%
323	Uterine Neoplasms	2.3%
324	Vaginal Neoplasms	2.3%
325	Vulvar Neoplasms	2.3%
326	Uterine Cancer	2.3%
327	Fallopian Tube Neoplasms	2.2%
328	Zollinger-Ellison syndrome	2%
329	Meningeal Carcinomatosis	2%
330	Pharyngeal Neoplasms	2%
331	Central Nervous System Cysts	1.9%
332	Bile Duct Neoplasms	1.9%
333	gallbladder neoplasm	1.9%
334	Intestinal Neoplasms	1.9%
335	Penile Neoplasms	1.9%
336	Prostatic Neoplasms	1.9%
337	Stomach Neoplasms	1.9%
338	Polycythemia Vera	1.9%
339	Laryngeal neoplasm	1.7%
340	Bronchial Neoplasms	1.6%
341	Bladder Neoplasm	1.6%
342	Kidney Neoplasm	1.6%
343	Ureteral Neoplasms	1.6%
344	Urethral Neoplasms	1.6%
345	Multiple Pulmonary Nodules	1.6%
346	Supratentorial Neoplasms	1.6%
347	Endometrial Neoplasms	1.6%
348	Hypopharyngeal Neoplasms	1.4%
349	Pleural Effusion, Malignant	1.4%
350	Hypopharyngeal Cancer	1.4%
351	Parotid Neoplasms	1.3%
352	Prostatic Neoplasms, Castration-Resistant	1.3%
353	Nelson Syndrome	1.3%
354	Brain Stem Neoplasms	1.3%
355	Cecal Neoplasms	1.1%
356	Duodenal Neoplasms	1.1%
357	Choroid Plexus Papilloma	1.1%
358	Tonsillar Neoplasms	1.1%
359	Cerebellar Neoplasms	1.1%
360	Nasopharyngeal Neoplasms	1%
361	Colorectal Neoplasms	1%
362	Radicular Cyst	0.9%
363	Paranasal Sinus Neoplasms	0.9%
364	Appendiceal Neoplasms	0.9%
365	Colonic Neoplasms	0.9%
366	Rectal Neoplasms	0.9%
367	Maxillary Sinus Neoplasms	0.7%
368	Anus Neoplasms	0.7%
369	Sigmoid Neoplasms	0.7%

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