MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Osteoma

(UMLS:C0029440)

Definition:: A benign tumor composed of bone tissue or a hard tumor of bonelike structure developing on a bone (homoplastic osteoma) or on other structures (heteroplastic osteoma). (From Dorland, 27th ed)
UMLS ID:: C0029440
MeSH ID:: D010016

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.450.565.575.625

Synonym(s)

Osteoma

OSTEOMA

OSTEOMA, BENIGN

Osteoma NOS

Osteoma, NOS

Osteoma, no ICD-O subtype

Osteoma, no International Classification of Diseases for Oncology subtype

benign osteoma of bone

osteoma

10.

osteomas

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Alendronate	FAERS: 8 Canada Vigilance: 1	Canada Vigilance US FAERS
2	Isotretinoin	FAERS: 3	US FAERS
3	salmon calcitonin	FAERS: 3	US FAERS
4	Zoledronic Acid	FAERS: 2	OFFSIDES US FAERS
5	Amiodarone	FAERS: 1	US FAERS
6	Bortezomib	FAERS: 1	US FAERS
7	Imatinib Mesylate	FAERS: 1	US FAERS
8	Minocycline	FAERS: 1	US FAERS
9	Risedronic Acid	FAERS: 1	US FAERS
10	Teriparatide	FAERS: 1	US FAERS
11	paricalcitol	FAERS: 1	US FAERS
12	tiludronic acid	FAERS: 1	US FAERS
13	Baclofen		OFFSIDES
14	Brimonidine Tartrate		OFFSIDES
15	Estrogens, Conjugated (USP)		OFFSIDES
16	Fluocinonide		OFFSIDES
17	Ganciclovir		OFFSIDES
18	Gatifloxacin		OFFSIDES
19	Hydroxychloroquine		OFFSIDES
20	Ketoconazole		OFFSIDES
21	Linezolid		OFFSIDES
22	Metolazone		OFFSIDES
23	Mupirocin		OFFSIDES
24	Mycophenolic Acid		OFFSIDES
25	Nabumetone		OFFSIDES
26	Pamidronate		OFFSIDES
27	Progesterone		OFFSIDES
28	Raloxifene Hydrochloride		OFFSIDES
29	Sumatriptan		OFFSIDES
30	Temozolomide		OFFSIDES
31	Tenofovir		OFFSIDES
32	Zidovudine		OFFSIDES
33	Zolpidem		OFFSIDES
34	fosamprenavir		OFFSIDES
35	rizatriptan		OFFSIDES
36	rizatriptan		OFFSIDES
37	tegaserod		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Osteoblastoma	49.2%
2	Giant Cell Tumor of Bone	48.7%
3	Osteosarcoma	44.1%
4	Myxoma	36%
5	Neoplasms, Fibrous Tissue	36%
6	Chondroma	36%
7	Enchondroma	36%
8	Chondrosarcoma	35.3%
9	synovial sarcoma	35.3%
10	Clear Cell Sarcoma of Soft Tissue	35.3%
11	Sarcoma	28.5%
12	Fibrosarcoma	27.1%
13	fibroma	23.8%
14	Fibromatosis	23.8%
15	Chondromatosis	23.8%
16	Malignant Fibrous Histiocytoma	23.1%
17	leukemia	22.7%
18	Neoplasms, Germ Cell and Embryonal	22.7%
19	Neoplasms, Glandular and Epithelial	22.7%
20	Germ Cell Cancer	22.7%
21	leiomyosarcoma	22.5%
22	liposarcoma	22.5%
23	Angiomyolipoma	22.5%
24	Alveolar Soft Part Sarcoma	22.5%
25	Carcinosarcoma	19.5%
26	Hemangiosarcoma	19.5%
27	lymphangiosarcoma	19.5%
28	Dermatofibrosarcoma	19.3%
29	Dermatofibrosarcoma Protuberans	19.3%
30	Mastocytosis	18.7%
31	Gastrointestinal Stromal Tumors	18.4%
32	Fibromatosis, Aggressive	17.8%
33	Fibromatosis, Abdominal	17.8%
34	Phyllodes Tumor	16.8%
35	Lipoma	16.8%
36	Myoma	16.8%
37	Angiolipoma	16.8%
38	Myelolipoma	16.8%
39	Smooth Muscle Tumor	16.8%
40	Desmoplastic Small Round Cell Tumor	16.8%
41	Adenofibroma	16.7%
42	Fibroadenoma	16.7%
43	Neuroectodermal Tumors	16.4%
44	Mastocytoma	16.1%
45	Sarcoma, Myeloid	16%
46	Mastocytosis, Systemic	16%
47	Hamartoma	15.3%
48	Neoplasms, Hormone-Dependent	15.3%
49	Neoplasms, Multiple Primary	15.3%
50	Paraneoplastic Syndromes	15.3%
51	Precancerous Conditions	15.3%
52	Neoplasms, Second Primary	15.3%
53	Histiocytic Disorders, Malignant	15.1%
54	Rhabdomyosarcoma	14.8%
55	Neoplasms, Neuroepithelial	13.4%
56	Gliomatosis cerebri	13.4%
57	Carcinoma 256, Walker	13.1%
58	Sarcoma, Experimental	12.3%
59	Adenoma	12.2%
60	Ameloblastoma	12.2%
61	Angiokeratoma	12.2%
62	Carcinoma	12.2%
63	Chordoma	12.2%
64	Hemangioma	12.2%
65	hemangiopericytoma	12.2%
66	Lymphangioma	12.2%
67	Mesenchymoma	12.2%
68	Nevus	12.2%
69	Teratoma	12.2%
70	Hepatoblastoma	12.2%
71	Mixed Tumor, Mullerian	12.2%
72	Germinoma	12.2%
73	Teratocarcinoma	12.2%
74	Angiofibroma	12.2%
75	Epithelioma	12.2%
76	Lymphoma	11.3%
77	Neurofibrosarcoma	11.2%
78	Rhabdomyoma	11.1%
79	Alveolar rhabdomyosarcoma	11.1%
80	melanoma	10.8%
81	Meningioma	10.4%
82	Sarcoma 180	10.2%
83	Cyst	10.2%
84	Neoplastic Processes	10.2%
85	Neoplastic Syndromes, Hereditary	10.2%
86	Pregnancy Complications, Neoplastic	10.2%
87	Trophoblastic Neoplasms	10%
88	Leukemia, Experimental	10%
89	Carcinoma, Ehrlich Tumor	9.9%
90	Dermoid Cyst	9.9%
91	Carcinoma, Lewis Lung	9.9%
92	Neoplasms, Experimental	9.9%
93	Composite Lymphoma	9.8%
94	Leukemia, Plasma Cell	9.7%
95	Lymphangioleiomyomatosis	9.6%
96	Basal cell carcinoma	9.6%
97	Carcinoma, Papillary	9.6%
98	Squamous cell carcinoma	9.6%
99	Craniopharyngioma	9.6%
100	Cystadenoma	9.6%
101	Mesothelioma	9.6%
102	Neuroectodermal Tumor, Melanotic	9.6%
103	Neuroendocrine Tumors	9.6%
104	Carcinoma, Basal Cell	9.6%
105	Dupuytren Contracture	9.3%
106	Endometrial Stromal Sarcoma	9.3%
107	Urticaria Pigmentosa	9.1%
108	Adenoma, Acidophil	8.4%
109	Ganglioneuroma	8.4%
110	Glioma	8.4%
111	Malignant Glioma	8.4%
112	Plasmacytoma	8.2%
113	Malignant histiocytosis	8.1%
114	Histiocytic sarcoma	8.1%
115	Leukemia, Radiation-Induced	8.1%
116	Cystadenocarcinoma	8%
117	Mucoepidermoid Carcinoma	8%
118	Leukemia L1210	7.6%
119	Leukemia P388	7.6%
120	Acanthoma	7.6%
121	Abdominal Neoplasms	7.6%
122	Erythroplasia	7.6%
123	Follicular cyst	7.6%
124	Head and Neck Neoplasms	7.6%
125	Mucocele	7.6%
126	Pilonidal Cyst	7.6%
127	Soft Tissue Neoplasms	7.6%
128	Thoracic Neoplasms	7.6%
129	Thyroglossal Cyst	7.6%
130	Synovial Cyst	7.6%
131	Aberrant Crypt Foci	7.6%
132	Neoplasms, Radiation-Induced	7.4%
133	Thymoma	7.3%
134	Melanoma, Experimental	7.3%
135	Adenocarcinoma	7.2%
136	Carcinoma in Situ	7.2%
137	Carcinoma, Transitional Cell	7.2%
138	Dysgerminoma	7.2%
139	Hemangioendothelioma	7.2%
140	Neuroma	7.2%
141	Papilloma	7.2%
142	Pseudomyxoma Peritonei	7.2%
143	Seminoma	7.2%
144	Papillomatosis	7.2%
145	Adenomatosis, Pulmonary	7.2%
146	Adenomatous Polyps	7.2%
147	Carcinoma, Large Cell	7.2%
148	Carcinoma, Small Cell	7.2%
149	Carcinoid Tumor	7.1%
150	Neurilemmoma	7.1%
151	Hutchinson's Melanotic Freckle	7.1%
152	Melanoma, Amelanotic	7.1%
153	Medulloblastoma	6.8%
154	Multiple Endocrine Neoplasia	6.6%
155	Choriocarcinoma	6.5%
156	Carcinoma, Lobular	6.5%
157	Bowen's Disease	6.3%
158	Paraganglioma	6.3%
159	Hodgkin Disease	6.1%
160	Lymphoma, Non-Hodgkin	6.1%
161	Paraneoplastic Encephalomyelitis	6%
162	Astrocytoma	5.9%
163	Ependymoma	5.9%
164	oligodendroglioma	5.9%
165	Ganglioglioma	5.9%
166	gliosarcoma	5.9%
167	Anaplastic astrocytoma	5.9%
168	Anaplastic Oligodendroglioma	5.9%
169	Mammary Neoplasms, Experimental	5.8%
170	Digestive System Neoplasms	5.4%
171	Endocrine Gland Neoplasms	5.4%
172	Eye Neoplasms	5.4%
173	Nervous System Neoplasms	5.4%
174	Malignant Carcinoid Syndrome	5.3%
175	Bone neoplasms	5.1%
176	Leukoplakia	5.1%
177	Lymphocele	5.1%
178	Pancreatic Cyst	5.1%
179	Skin Neoplasms	5.1%
180	Hematologic Neoplasms	5.1%
181	Barrett Esophagus	5%
182	Breast Cyst	5%
183	Actinic keratosis	5%
184	Mediastinal Cyst	5%
185	Neoplasm Invasiveness	5%
186	Neoplasm Metastasis	5%
187	Neoplasm Recurrence, Local	5%
188	Parovarian Cyst	5%
189	Pericardial Cyst	5%
190	Splenic Neoplasms	5%
191	Thymic Cyst	5%
192	Carcinogenesis	5%
193	Myxoid cyst	5%
194	Metastasis	5%
195	Primary amyloidosis	4.9%
196	Retinoblastoma	4.9%
197	Lymphomatoid Granulomatosis	4.9%
198	Leukemia, Myelomonocytic, Chronic	4.8%
199	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	4.8%
200	Adenoid Cystic Carcinoma	4.8%
201	Adenocarcinoma, Clear Cell	4.8%
202	Cholangiocarcinoma	4.8%
203	Cervical Intraepithelial Neoplasia	4.8%
204	Hemangioblastoma	4.8%
205	Lymphoma, Extranodal NK-T-Cell	4.8%
206	Pheochromocytoma	4.7%
207	Glioblastoma	4.7%
208	Neuroblastoma	4.7%
209	Glioblastoma Multiforme	4.7%
210	Nephroblastoma	4.7%
211	Tuberous Sclerosis	4.6%
212	Ganglioneuroblastoma	4.1%
213	Retroperitoneal Neoplasms	4.1%
214	Hepatocellular Adenoma	3.9%
215	Mesoblastic Nephroma	3.9%
216	Basal Cell Nevus Syndrome	3.8%
217	Sturge-Weber Syndrome	3.7%
218	Corpus Luteum Cyst	3.7%
219	Ovarian Cysts	3.7%
220	Hemangioma, Cavernous	3.6%
221	Carcinoid Heart Disease	3.6%
222	Leukemia, T-Cell	3.6%
223	Leukemia, B-Cell	3.6%
224	neurofibroma	3.6%
225	Hydatidiform Mole	3.6%
226	Lymphoma, Follicular	3.6%
227	T-Cell Lymphoma	3.6%
228	Mantle cell lymphoma	3.6%
229	Klatskin Tumor	3.6%
230	Multiple Endocrine Neoplasia Type 1	3.5%
231	Waldenstrom Macroglobulinemia	3.5%
232	Multiple Myeloma	3.5%
233	Parathyroid Neoplasms	3.4%
234	Peritoneal Neoplasms	3.4%
235	Thyroid Neoplasm	3.4%
236	Thyroid carcinoma	3.4%
237	Carcinoma, Pancreatic Ductal	3.3%
238	Liver Neoplasms, Experimental	3.3%
239	Prolactinoma	3.2%
240	Growth Hormone-Secreting Pituitary Adenoma	3.2%
241	Leukemia, Myeloid, Chronic-Phase	3.2%
242	Choledochal Cyst	3.1%
243	Acoustic Neuroma	3%
244	Peutz-Jeghers Syndrome	3%
245	Pancreatic Neoplasm	2.8%
246	Mouth Neoplasms	2.8%
247	Central Nervous System Neoplasms	2.8%
248	Vascular Neoplasms	2.8%
249	Thymus Neoplasms	2.8%
250	granulosa cell tumor	2.8%
251	Carcinoma, Ovarian Epithelial	2.8%
252	Genital Neoplasms, Female	2.7%
253	Pancreatic Pseudocyst	2.7%
254	Lymphatic Metastasis	2.7%
255	Neoplasms, Unknown Primary	2.7%
256	Leukemic Infiltration	2.7%
257	Breast Neoplasms, Male	2.7%
258	Neoplasm Micrometastasis	2.7%
259	Triple Negative Breast Neoplasms	2.7%
260	Tracheal Neoplasms	2.7%
261	Optic Nerve Glioma	2.7%
262	Adenomatous Polyposis Coli	2.7%
263	Leukoplakia, Oral	2.6%
264	Paraneoplastic Cerebellar Degeneration	2.6%
265	Vipoma	2.6%
266	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	2.4%
267	Leukemia, Large Granular Lymphocytic	2.4%
268	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	2.4%
269	Lymphoma, T-Cell, Cutaneous	2.4%
270	Lymphoma, AIDS-Related	2.4%
271	Enteropathy-Associated T-Cell Lymphoma	2.4%
272	Primary Effusion Lymphoma	2.4%
273	insulinoma	2.3%
274	Esophageal Neoplasms	2.2%
275	Limbic Encephalitis	2.2%
276	Adrenocortical carcinoma	2.1%
277	Adrenal Gland Neoplasms	2.1%
278	Gastrointestinal Neoplasms	2.1%
279	Genital Neoplasms, Male	2.1%
280	Liver neoplasms	2.1%
281	Uveal Neoplasms	2.1%
282	Nasopharyngeal carcinoma	2.1%
283	Urologic Neoplasms	2.1%
284	Sebaceous Gland Neoplasms	2.1%
285	Spinal Neoplasms	2.1%
286	Bone Marrow Neoplasms	2.1%
287	Polycystic Ovary Syndrome	2%
288	Thyroid Nodule	2%
289	Gastrinoma	1.9%
290	Glucagonoma	1.9%
291	Denys-Drash Syndrome	1.9%
292	Lambert-Eaton Myasthenic Syndrome	1.9%
293	Testicular Neoplasms	1.9%
294	Leydig Cell Tumor	1.9%
295	Renal Cell Carcinoma	1.8%
296	Papillary Renal Cell Carcinoma	1.8%
297	Mycosis Fungoides	1.8%
298	Lymphomatoid Papulosis	1.8%
299	Plasmablastic lymphoma	1.8%
300	Carcinoma, Endometrioid	1.7%
301	Xeroderma Pigmentosum	1.7%
302	Opsoclonus-Myoclonus Syndrome	1.7%
303	Meningeal Neoplasms	1.6%
304	Burkitt Lymphoma	1.6%
305	Myelitis, Transverse	1.5%
306	ovarian neoplasm	1.4%
307	Nose Neoplasms	1.3%
308	Ear Neoplasms	1.3%
309	Eyelid Neoplasms	1.3%
310	Lung Neoplasms	1.3%
311	Pleural Neoplasms	1.3%
312	Cell Transformation, Viral	1.2%
313	Brain Neoplasms	1.2%
314	Salivary Gland Neoplasms	1.2%
315	Spinal Cord Neoplasms	1.2%
316	Tongue Neoplasms	1.2%
317	Uterine Neoplasms	1.2%
318	Vaginal Neoplasms	1.2%
319	Vulvar Neoplasms	1.2%
320	Uterine Cancer	1.2%
321	Sezary Syndrome	1.2%
322	Fallopian Tube Neoplasms	1.2%
323	Palatal Neoplasms	1.2%
324	Pituitary Adenoma	1.1%
325	Pituitary Neoplasms	1.1%
326	Meningeal Carcinomatosis	1.1%
327	Zollinger-Ellison syndrome	1%
328	Pharyngeal Neoplasms	1%
329	Central Nervous System Cysts	1%
330	Bile Duct Neoplasms	1%
331	gallbladder neoplasm	1%
332	Intestinal Neoplasms	1%
333	Penile Neoplasms	1%
334	Prostatic Neoplasms	1%
335	Stomach Neoplasms	1%
336	Polycythemia Vera	1%
337	Laryngeal neoplasm	0.9%
338	Bronchial Neoplasms	0.8%
339	Bladder Neoplasm	0.8%
340	Kidney Neoplasm	0.8%
341	Ureteral Neoplasms	0.8%
342	Urethral Neoplasms	0.8%
343	Multiple Pulmonary Nodules	0.8%
344	Supratentorial Neoplasms	0.8%
345	Endometrial Neoplasms	0.8%
346	Hypopharyngeal Neoplasms	0.7%
347	Pleural Effusion, Malignant	0.7%
348	Hypopharyngeal Cancer	0.7%
349	Parotid Neoplasms	0.6%
350	Prostatic Neoplasms, Castration-Resistant	0.6%
351	Nelson Syndrome	0.6%
352	Brain Stem Neoplasms	0.6%
353	Cecal Neoplasms	0.5%
354	Duodenal Neoplasms	0.5%
355	Choroid Plexus Papilloma	0.5%
356	Tonsillar Neoplasms	0.5%
357	Cerebellar Neoplasms	0.5%
358	Nasopharyngeal Neoplasms	0.5%
359	Colorectal Neoplasms	0.5%
360	Paranasal Sinus Neoplasms	0.4%
361	Radicular Cyst	0.4%
362	Appendiceal Neoplasms	0.4%
363	Colonic Neoplasms	0.4%
364	Rectal Neoplasms	0.4%
365	Maxillary Sinus Neoplasms	0.3%
366	Anus Neoplasms	0.3%
367	Sigmoid Neoplasms	0.3%

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