MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Autonomic Dysreflexia

(UMLS:C0238015)

Definition:: A syndrome associated with damage to the spinal cord above the mid thoracic level (see SPINAL CORD INJURIES) characterized by a marked increase in the sympathetic response to minor stimuli such as bladder or rectal distention. Manifestations include HYPERTENSION; TACHYCARDIA (or reflex bradycardia); FEVER; FLUSHING; and HYPERHIDROSIS. Extreme hypertension may be associated with a STROKE. (From Adams et al., Principles of Neurology, 6th ed, pp538 and 1232; J Spinal Cord Med 1997;20(3):355-60)
UMLS ID:: C0238015
MeSH ID:: D020211

Classification:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.177.090|C10.900.850.250

Synonym(s)

Autonomic Dysreflexia

AUTONOMIC HYPERREFLEXIA

Autonomic dysreflexia

Dysreflexia

autonomic dysreflexia

autonomic hyperreflexia

dysreflexia

rndx autonomic dysreflexia

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Baclofen	FAERS: 30 Canada Vigilance: 1		Canada Vigilance US FAERS
2	Alendronate	FAERS: 11		US FAERS
3	Sumatriptan	FAERS: 4		US FAERS
4	Docetaxel	FAERS: 2		US FAERS
5	Droxidopa	FAERS: 2		US FAERS
6	Nifedipine	FAERS: 2		US FAERS
7	Sumatriptan	FAERS: 2		US FAERS
8	Citalopram	FAERS: 1		US FAERS
9	Dioctyl Sulfosuccinic Acid	FAERS: 1		US FAERS
10	Furosemide	FAERS: 1		US FAERS
11	Gabapentin	FAERS: 1		US FAERS
12	Misoprostol		8835039	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Dysautonomia	34.9%
2	Complex Regional Pain Syndromes	34.5%
3	Multiple System Atrophy	30.5%
4	Central Cord Syndrome	28.6%
5	Cranial nerve diseases	26.8%
6	Demyelinating Diseases	26.8%
7	Demyelination	26.8%
8	Neuromuscular Diseases	26.8%
9	Chronobiology Disorders	26.8%
10	Sweating, Gustatory	25.6%
11	Auriculotemporal Syndrome	25.6%
12	Causalgia	25.3%
13	Reflex Sympathetic Dystrophy	25.2%
14	Peripheral Nerve Injuries	25%
15	Motor Neuron Disease	24.6%
16	Striatonigral Degeneration	23.7%
17	Craniocerebral Trauma	22.8%
18	Stiff-Person Syndrome	21.8%
19	Horner Syndrome	21.3%
20	Encephalomyelitis	20.7%
21	Prion Diseases	20.7%
22	Polyradiculoneuropathy	20.6%
23	Polyradiculoneuritis	20.6%
24	Shy-Drager Syndrome	20.3%
25	Ocular Motility Disorders	20.3%
26	Cyclophoria	20.3%
27	Spinal Muscular Atrophy	20.3%
28	Progressive Muscular Atrophy	20.3%
29	Postural Orthostatic Tachycardia Syndrome	20.2%
30	Pneumocephalus	20.1%
31	Meningoencephalitis	20%
32	Nervous System Neoplasms	20%
33	Neurologic Manifestations	20%
34	Neurotoxicity Syndromes	20%
35	Restless Legs Syndrome	19.6%
36	Parkinson Disease	19.5%
37	Amyotrophic Lateral Sclerosis	19.1%
38	Brain Injuries	18.9%
39	Olfactory Nerve Injuries	18.9%
40	Marchiafava-Bignami Disease	18.8%
41	Ophthalmoplegic Migraine	18.8%
42	Orthostatic intolerance	18.6%
43	Subacute Combined Degeneration	18.5%
44	Lewy Body Disease	17.7%
45	Guillain-Barre Syndrome	17.6%
46	Myelitis	16.9%
47	Progressive bulbar palsy	16.9%
48	Bulbar palsy	16.9%
49	Dandy-Walker Syndrome	16.9%
50	Poliomyelitis	16.8%
51	Epilepsy, Post-Traumatic	16.5%
52	Myasthenia Gravis	16.4%
53	Asterixis	16.4%
54	Ballismus	16.4%
55	Coma, Post-Head Injury	16.4%
56	Brain Diseases	16.3%
57	Meningitis	16.3%
58	Movement Disorders	16.3%
59	Pachymeningitis	16.3%
60	Spinal Cord Diseases	16.3%
61	Vagus Nerve Disorder	16.3%
62	Glossopharyngeal Neuralgia	16.3%
63	Abducens Nerve Diseases	16.3%
64	Heavy Metal Poisoning, Nervous System	16.3%
65	Neuromuscular Junction Diseases	16.3%
66	Tauopathies	16.3%
67	Trochlear Nerve Diseases	16.3%
68	Peripheral Nervous System Diseases	16.3%
69	Facial Nerve Injuries	16.2%
70	Leukoencephalitis, Acute Hemorrhagic	16.2%
71	Sleep Wake Disorders	16.2%
72	Progressive supranuclear palsy	16.1%
73	Miller Fisher Syndrome	16%
74	Epidural Abscess	15.6%
75	Brain Hemorrhage, Traumatic	15.4%
76	MPTP Poisoning	15.3%
77	Facial Injuries	15.3%
78	Myelitis, Transverse	15.2%
79	Hypotension, Orthostatic	15.1%
80	Subdural Effusion	15.1%
81	Parkinsonian Disorders	15.1%
82	Nocturnal Myoclonus Syndrome	15.1%
83	Post-Exercise Hypotension	15.1%
84	Neuroleptic Malignant Syndrome	15%
85	Myelinolysis, Central Pontine	15%
86	Encephalomyelitis, Acute Disseminated	15%
87	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	15%
88	Brain Injuries, Diffuse	14.6%
89	Traumatic Brain Injury	14.6%
90	Neuromyelitis Optica	14.5%
91	Dystonia Musculorum Deformans	14.4%
92	Lambert-Eaton Myasthenic Syndrome	14.3%
93	Chronic Fatigue Syndrome	14.3%
94	Opsoclonus-Myoclonus Syndrome	14.2%
95	Sleep Disorders, Circadian Rhythm	14.1%
96	Botulism	13.6%
97	Dyskinesia, Drug-Induced	13.6%
98	Central Nervous System Cysts	13.6%
99	Brain Concussion	13.5%
100	Brain Neoplasms	13.4%
101	Multiple Sclerosis	13.4%
102	Spinal Cord Neoplasms	13.4%
103	Meige Syndrome	13.3%
104	Brachial Plexus Neuritis	13.3%
105	Neuralgic Amyotrophy	13.3%
106	Cerebral Ventriculitis	13.3%
107	Cerebrospinal Fluid Otorrhea	13.3%
108	Cerebrospinal Fluid Rhinorrhea	13.3%
109	Carotid Artery Injuries	13.2%
110	Leukoencephalopathy, Progressive Multifocal	13%
111	Spinal Cord Injuries	12.9%
112	Central Nervous System Infection	12.7%
113	Myopathy	12.7%
114	Optic Neuropathy	12.7%
115	Diffuse Axonal Injury	12.5%
116	Tarsal Tunnel Syndrome	12.4%
117	Cauda Equina Syndrome	12.4%
118	Posterior Leukoencephalopathy Syndrome	12.4%
119	Posterior reversible encephalopathy syndrome	12.4%
120	Lafora Disease	12.4%
121	Unverricht-Lundborg Syndrome	12.4%
122	Limbic Encephalitis	12.3%
123	Facial Nerve Diseases	12.3%
124	Parasomnia	12.3%
125	Dyssomnias	12.3%
126	Scrapie	12.2%
127	Huntington Disease	12.2%
128	Presenile dementia	12.1%
129	Senile dementia	12.1%
130	Meningitis, Bacterial	12.1%
131	Meningitis, Fungal	12.1%
132	Vestibulocochlear Nerve Diseases	12.1%
133	Decerebrate State	12.1%
134	Hemiparesis	12.1%
135	Hydranencephaly	12.1%
136	Meningism	12.1%
137	Neural Tube Defects	12.1%
138	Paresis	12.1%
139	Seizures	12.1%
140	Sensation Disorders	12.1%
141	Tethered Cord Syndrome	12.1%
142	Central Nervous System Neoplasms	12.1%
143	Complex partial seizures	12.1%
144	Iniencephaly	12.1%
145	Craniorachischisis	12.1%
146	Exencephaly	12.1%
147	Monoparesis	12.1%
148	Septo-Optic Dysplasia	12.1%
149	Cortical Dysplasia	12.1%
150	Neurogenic Inflammation	12.1%
151	Gait Disorders, Neurologic	12.1%
152	Neuromuscular Manifestations	12.1%
153	Malformations of Cortical Development	12.1%
154	Chorea	12%
155	Cerebellar Neoplasms	12%
156	Acrodynia	12%
157	Lupus Vasculitis, Central Nervous System	11.8%
158	Vertebral Artery Dissection	11.8%
159	Charcot-Marie-Tooth Disease	11.8%
160	Akathisia, Drug-Induced	11.7%
161	Myoclonic Epilepsy	11.6%
162	Epilepsy, Temporal Lobe	11.6%
163	Epilepsy, Rolandic	11.6%
164	Myasthenia Gravis, Autoimmune, Experimental	11.6%
165	Benign Rolandic Epilepsy	11.6%
166	Akinetic Mutism	11.4%
167	Anoxic Encephalopathy	11.4%
168	Arachnoiditis	11.4%
169	Basal Ganglia Diseases	11.4%
170	Brain Damage, Chronic	11.4%
171	Cerebellar Diseases	11.4%
172	Encephalitis	11.4%
173	Encephalomalacia	11.4%
174	Epilepsy	11.4%
175	Hydrocephalus	11.4%
176	Congenital Hydrocephalus	11.4%
177	Hypothalamic Diseases	11.4%
178	Aseptic Meningitis	11.4%
179	Neuritis	11.4%
180	Polyneuritis	11.4%
181	Radiculitis	11.4%
182	Syringomyelia	11.4%
183	Thalamic Diseases	11.4%
184	Intracranial Hypertension	11.4%
185	Polyneuropathy	11.4%
186	Mononeuritis	11.4%
187	Aura	11.4%
188	Leukoencephalopathy	11.4%
189	Essential Tremor	11.4%
190	Neuroaxonal Dystrophies	11.4%
191	Familial Tremor	11.4%
192	Headache Disorders	11.4%
193	Mononeuropathies	11.4%
194	Intracranial Hypotension	11.4%
195	Brachial Plexus Neuropathies	11.4%
196	Radiculopathy	11.4%
197	Mononeuropathy Multiplex	11.4%
198	Nerve Root Compression	11.4%
199	Brain Edema	11.4%
200	Brain Hypoxia	11.4%
201	Aqueductal Stenosis	11.4%
202	Pneumorrhachis	11.4%
203	Writer's Cramp	11.4%
204	Trauma, Nervous System	11.3%
205	Brain Abscess	11.3%
206	Ophthalmoplegia	11.3%
207	External Ophthalmoplegia	11.3%
208	Dementia, Vascular	11.1%
209	Brain Death	11%
210	Canavan Disease	11%
211	Alexander Disease	11%
212	Friedreich Ataxia	10.8%
213	Juvenile Myoclonic Epilepsy	10.7%
214	Myoclonic Epilepsies, Progressive	10.7%
215	Creutzfeldt-Jakob disease	10.7%
216	Basal Ganglia Cerebrovascular Disease	10.7%
217	Vasculitis, Central Nervous System	10.6%
218	Jet Lag Syndrome	10.6%
219	Cerebellar Ataxia	10.6%
220	Supratentorial Neoplasms	10.6%
221	Torticollis	10.6%
222	Multiple Sclerosis, Chronic Progressive	10.6%
223	Multiple Sclerosis, Relapsing-Remitting	10.6%
224	Brain Contusion	10.4%
225	Autonomic Dysreflexia	10.3%
226	Tuberculosis, Meningeal	10.2%
227	Ataxia Telangiectasia	10.2%
228	Amblyopia	10.1%
229	Myotonia Congenita	10.1%
230	Pupil Disorders	10%
231	Paraneoplastic Cerebellar Degeneration	10%
232	Neurobehavioral Manifestations	10%
233	Carpal Tunnel Syndrome	10%
234	Vascular Headaches	10%
235	Neuritis, Autoimmune, Experimental	9.9%
236	Tuberous Sclerosis	9.9%
237	Gait Ataxia	9.9%
238	neurofibroma	9.9%
239	Hypoxia-Ischemia, Brain	9.9%
240	Sciatica	9.9%
241	Tardive Dyskinesia	9.9%
242	Persistent Vegetative State	9.9%
243	Vocal Cord Paralysis	9.8%
244	Subarachnoid Hemorrhage, Traumatic	9.7%
245	Carotid Artery, Internal, Dissection	9.7%
246	Eye Injuries	9.7%
247	Paraneoplastic Encephalomyelitis	9.7%
248	Uveomeningoencephalitic Syndrome	9.6%
249	Sturge-Weber Syndrome	9.5%
250	Vertigo	9.5%
251	Alcohol-Induced Disorders, Nervous System	9.5%
252	Cubital Tunnel Syndrome	9.2%
253	Myotonic Dystrophy	9.2%
254	Alice in Wonderland Syndrome	9.2%
255	Brain Stem Neoplasms	9.2%
256	Cerebral Palsy	9%
257	Epilepsies, Partial	9%
258	Epilepsy, Generalized	9%
259	Pseudotumor Cerebri	9%
260	Sciatic Neuropathy	9%
261	Hypertensive Encephalopathy	9%
262	Ulnar Neuropathies	9%
263	Lesion of Sciatic Nerve	9%
264	Simple Partial Seizures	9%
265	Epilepsy, Reflex	9%
266	Ulnar Neuritis	9%
267	Radial nerve compression	9%
268	Radial Tunnel Syndrome	9%
269	Peroneal Neuropathies	9%
270	Radial Neuropathy	9%
271	Median Neuropathy	9%
272	Sciatic Nerve Palsy	9%
273	Femoral Neuropathy	9%
274	Tibial Neuropathy	9%
275	Ulnar Nerve Palsy	9%
276	Radial nerve palsy	9%
277	Headache Disorders, Primary	9%
278	Headache Disorders, Secondary	9%
279	Medication overuse headache	9%
280	Pituitary Adenoma	8.9%
281	Pituitary Neoplasms	8.9%
282	Hepatolenticular Degeneration	8.9%
283	Leukomalacia, Periventricular	8.9%
284	Brain Diseases, Metabolic	8.6%
285	Cerebrovascular Disorders	8.6%
286	Myositis	8.6%
287	Optic Atrophy	8.6%
288	Optic Neuritis	8.6%
289	Papilledema	8.6%
290	Strabismus	8.6%
291	Tolosa-Hunt Syndrome	8.6%
292	Cerebrovascular Insufficiency	8.6%
293	Isaacs syndrome	8.6%
294	Arsenic Poisoning	8.6%
295	Dementia	8.6%
296	Myotonic Disorders	8.6%
297	Central Nervous System Fungal Infections	8.6%
298	Conus Medullaris Syndrome	8.6%
299	Myasthenic Syndromes, Congenital	8.6%
300	Spinal Cord Vascular Diseases	8.6%
301	Akathisia	8.5%
302	Restlessness	8.5%
303	Psychomotor Agitation	8.5%
304	Choroid Plexus Papilloma	8.5%
305	Diabetic Neuropathies	8.5%
306	Facial Neuralgia	8.5%
307	Diabetic Amyotrophy	8.5%
308	Diabetic Autonomic Neuropathy	8.5%
309	Sleep Talking	8.5%
310	Manganese Poisoning	8.5%
311	Sleep Disorders, Intrinsic	8.5%
312	Anosmia	8.4%
313	Ataxia	8.4%
314	Athetosis	8.4%
315	Catalepsy	8.4%
316	Dystonia	8.4%
317	Hemiplegia	8.4%
318	Locked-In Syndrome	8.4%
319	Meningeal Neoplasms	8.4%
320	Meningomyelocele	8.4%
321	Muscle Hypertonia	8.4%
322	Muscle hypotonia	8.4%
323	Myoclonus	8.4%
324	Myotonia	8.4%
325	Neuralgia	8.4%
326	Paraplegia	8.4%
327	Pseudobulbar Palsy	8.4%
328	Quadriplegia	8.4%
329	Spasm	8.4%
330	Spastic Paraplegia	8.4%
331	Status Epilepticus	8.4%
332	Taste Disorders	8.4%
333	Tremor	8.4%
334	Spina Bifida	8.4%
335	Monoplegia	8.4%
336	Hypokinesia	8.4%
337	Paraparesis	8.4%
338	Bradykinesia	8.4%
339	Waxy flexibility	8.4%
340	Action Tremor	8.4%
341	Resting Tremor	8.4%
342	Dysosmia	8.4%
343	Quadriparesis	8.4%
344	Mercury Poisoning, Nervous System	8.4%
345	Olfaction Disorders	8.4%
346	Myokymia	8.4%
347	Lead Poisoning, Nervous System	8.4%
348	Vestibular Neuronitis	8.4%
349	Somatosensory Disorders	8.4%
350	Neuropathic pain	8.4%
351	Hyperkinesia	8.4%
352	Intention tremor	8.4%
353	Toxoplasmosis, Cerebral	8.4%
354	Optic Nerve Glioma	8.4%
355	Hematoma, Subdural	8.4%
356	Hematoma, Epidural, Cranial	8.4%
357	Basal Ganglia Hemorrhage	8.3%
358	Alcohol Withdrawal Seizures	8.3%
359	Meningitis, Cryptococcal	8.3%
360	Meningitis, Listeria	8.2%
361	Meningitis, Haemophilus	8.2%
362	Meningitis, Pneumococcal	8.2%
363	Frontotemporal dementia	8.2%
364	Voice Disorders	8.1%
365	Voice Disturbance	8.1%
366	Eye Burns	8.1%
367	Refsum Disease	8%
368	Amnesia, Transient Global	8%
369	Gait Apraxia	8%
370	Smith-Magenis syndrome	8%
371	Dural Arteriovenous Fistula	7.9%
372	Polyradiculopathy	7.8%
373	Post-Traumatic Headache	7.8%
374	Tension Headache	7.8%
375	Epilepsy, Complex Partial	7.8%
376	Migraine Disorders	7.8%
377	Abdominal Migraine	7.8%
378	Status Migrainosus	7.8%
379	Cervicogenic Headache	7.8%
380	Pituitary Apoplexy	7.8%
381	Putaminal Hemorrhage	7.8%
382	Brain Infarction	7.7%
383	Infarction, Middle Cerebral Artery	7.6%
384	Infarction, Anterior Cerebral Artery	7.6%
385	Infarction, Posterior Cerebral Artery	7.6%
386	Mitochondrial Encephalomyopathies	7.6%
387	Subacute Sclerosing Panencephalitis	7.6%
388	Alstrom Syndrome	7.5%
389	Hematoma, Subdural, Intracranial	7.4%
390	Hematoma, Subdural, Chronic	7.4%
391	Hematoma, Subdural, Acute	7.4%
392	Cluster Headache	7.2%
393	Migraine with Aura	7.2%
394	Familial Hemiplegic Migraine	7.2%
395	Chronic Paroxysmal Hemicrania	7.2%
396	SUNCT Syndrome	7.2%
397	Paroxysmal Hemicrania	7.2%
398	Hand-Arm Vibration Syndrome	7.1%
399	Pituitary Diseases	7.1%
400	Cerebral Infarction	7%
401	Brain Stem Infarctions	7%
402	Vision Disorders	7%
403	Metamorphopsia	7%
404	Visual Impairment	7%
405	Classical Lissencephalies and Subcortical Band Heterotopias	7%
406	Fibromyalgia	6.9%
407	Optic Neuropathy, Ischemic	6.9%
408	Anterior Ischemic Optic Neuropathy	6.9%
409	Central Nervous System Bacterial Infections	6.9%
410	Medial Tibial Stress Syndrome	6.9%
411	Facial Hemiatrophy	6.8%
412	Melkersson-Rosenthal Syndrome	6.8%
413	Mitochondrial Myopathies	6.8%
414	Thoracic Outlet Syndrome	6.8%
415	Anisocoria	6.8%
416	Confusion	6.8%
417	Facial paralysis	6.8%
418	Lethargy	6.8%
419	Memory Disorders	6.8%
420	Muscle Cramp	6.8%
421	Perceptual Disorders	6.8%
422	Psychomotor Disorders	6.8%
423	Tonic Pupil	6.8%
424	Eosinophilia-Myalgia Syndrome	6.8%
425	Anhedonia	6.8%
426	Disorientation	6.8%
427	Facial Paresis	6.8%
428	Memory Loss	6.8%
429	Hemisensory Neglect	6.8%
430	Dysacusis	6.8%
431	Corneal Scar	6.8%
432	Sleep Bruxism	6.8%
433	Lateral Medullary Syndrome	6.7%
434	Adrenoleukodystrophy	6.7%
435	Carotid Artery Diseases	6.7%
436	Brain Ischemia	6.7%
437	Esotropia	6.7%
438	Exotropia	6.7%
439	Sleep Apnea Syndromes	6.7%
440	Cerebrovascular accident	6.7%
441	Polymyositis	6.7%
442	Kluver-Bucy Syndrome	6.7%
443	Vasospasm, Intracranial	6.7%
444	Spinal Cord Ischemia	6.7%
445	Intracranial Arterial Diseases	6.7%
446	Anencephaly	6.7%
447	Meningocele	6.7%
448	Muscular Atrophy	6.7%
449	Respiratory Paralysis	6.7%
450	Encephalocele	6.7%
451	Reflex, Abnormal	6.7%
452	Hyporeflexia	6.7%
453	Hyperreflexia	6.7%
454	Disorders of Excessive Somnolence	6.7%
455	Sleep Initiation and Maintenance Disorders	6.7%
456	Night Terrors	6.7%
457	Somnambulism	6.7%
458	Tetany	6.7%
459	Trigeminal Nerve Disorder	6.7%
460	Transient Insomnia	6.7%
461	Sleep Paralysis	6.7%
462	Chronic Insomnia	6.7%
463	REM Sleep Behavior Disorder	6.7%
464	Hypersomnia	6.7%
465	Dermal Sinus	6.6%
466	Dysgeusia	6.6%
467	Formication	6.6%
468	Hyperalgesia	6.6%
469	Hyperesthesia	6.6%
470	Hypesthesia	6.6%
471	Language Disorders	6.6%
472	Numbness	6.6%
473	Paresthesia	6.6%
474	Paraparesis, Spastic	6.6%
475	Spina Bifida Cystica	6.6%
476	Trismus	6.6%
477	Spina Bifida Occulta	6.6%
478	Epilepsia Partialis Continua	6.6%
479	Hypogeusia	6.6%
480	Meningeal Carcinomatosis	6.6%
481	Brown-Sequard Syndrome	6.6%
482	Lissencephaly	6.6%
483	Polymicrogyria	6.6%
484	Pachygyria	6.6%
485	Schizencephaly	6.6%
486	Lockjaw	6.6%
487	Allodynia	6.6%
488	Lead Poisoning, Nervous System, Childhood	6.6%
489	Lead Poisoning, Nervous System, Adult	6.6%
490	Periventricular Nodular Heterotopia	6.6%
491	Ageusia	6.6%
492	Tuberculosis, Central Nervous System	6.6%
493	Auditory Perceptual Disorders	6.6%
494	Amyloid Neuropathies, Familial	6.6%
495	Alexia	6.5%
496	Dyslexia	6.5%
497	Moyamoya Disease	6.3%
498	West Nile Fever	6.3%
499	Neurofibrosarcoma	6.2%
500	Giant Cell Arteritis	6.2%
501	Temporal Arteritis	6.2%
502	MELAS Syndrome	6.2%
503	Corneal Perforation	6.1%
504	Acoustic Neuroma	6%
505	Empty Sella Syndrome	6%
506	Hyperpituitarism	6%
507	Hypopituitarism	6%
508	Hypophysitis	6%
509	Cerebral Arterial Diseases	5.8%
510	Vertebrobasilar Insufficiency	5.8%
511	Anterior Spinal Artery Syndrome	5.8%
512	Basilar Artery Stenosis	5.8%
513	Vertebral Artery Stenosis	5.8%
514	Sleep Apnea, Obstructive	5.8%
515	Sleep Apnea, Central	5.8%
516	Intracranial Hemorrhage, Hypertensive	5.8%
517	Transient Cerebral Ischemia	5.8%
518	Narcolepsy	5.8%
519	Trigeminal Neuralgia	5.8%
520	Kleine-Levin Syndrome	5.8%
521	Agraphia	5.8%
522	Anomia	5.8%
523	Cluttering	5.8%
524	Language Development Disorders	5.8%
525	Speech Disorders	5.8%
526	Syncope	5.8%
527	Stupor	5.8%
528	Dysgraphia	5.8%
529	Presyncope	5.8%
530	Dyslalia	5.8%
531	Duane Retraction Syndrome	5.7%
532	Consciousness Disorders	5.7%
533	Mental Retardation	5.7%
534	Muscle Weakness	5.7%
535	Depressed Level of Consciousness	5.7%
536	Mental deficiency	5.7%
537	Intellectual Disability	5.7%
538	Kearns-Sayre syndrome	5.7%
539	Mobius Syndrome	5.7%
540	Bell Palsy	5.7%
541	Catatonia	5.6%
542	Herpes Zoster Oticus	5.6%
543	Familial Periodic Paralysis	5.6%
544	Aphonia	5.6%
545	Sleep Deprivation	5.6%
546	Dysphonia	5.6%
547	Optic Atrophy, Hereditary, Leber	5.5%
548	Muscular Dystrophy	5.4%
549	Congenital nystagmus	5.4%
550	Orbital Myositis	5.4%
551	Hyperprolactinemia	5.4%
552	Diplopia	5.4%
553	Muscle Rigidity	5.4%
554	Muscle Spasticity	5.4%
555	Scotoma	5.4%
556	Photophobia	5.4%
557	Cogwheel Rigidity	5.4%
558	Hemifacial Spasm	5.4%
559	Amaurosis	5.4%
560	Blindness	5.4%
561	Nuchal Rigidity	5.4%
562	Reye Syndrome	5.4%
563	Neuroaspergillosis	5.4%
564	Pyomyositis	5.4%
565	Subclavian Steal Syndrome	5.4%
566	Pick Disease of the Brain	5.4%
567	Cataplexy	5.3%
568	Aphasia	5.3%
569	Articulation Disorders	5.3%
570	Echolalia	5.3%
571	Stuttering	5.3%
572	Dysphasia	5.3%
573	Intracranial Embolism and Thrombosis	5.3%
574	Hepatic Encephalopathy	5.3%
575	Agnosia	5.3%
576	Apraxias	5.3%
577	Hallucinations	5.3%
578	Hemianopsia	5.3%
579	Hyperacusis	5.3%
580	Tinnitus	5.3%
581	Visual Agnosia	5.3%
582	Anosognosia	5.3%
583	Wernicke-Korsakoff Syndrome	5.3%
584	Phonophobia	5.3%
585	Hearing Loss	5.3%
586	Sarcopenia	5.3%
587	Dysarthria	5.1%
588	Myalgia	4.8%
589	Neuronal Ceroid-Lipofuscinoses	4.7%
590	Toxoplasmosis, Congenital	4.7%
591	Malaria, Cerebral	4.7%
592	Pseudorabies	4.7%
593	Carotid Stenosis	4.7%
594	Intracranial Aneurysm	4.7%
595	Welander Distal Myopathy	4.7%
596	Neurocysticercosis	4.6%
597	Amaurosis Fugax	4.6%
598	Blindness, Cortical	4.6%
599	Dyscalculia	4.6%
600	Intracranial Arteriosclerosis	4.6%
601	Cerebral Atherosclerosis	4.6%
602	Rett Syndrome	4.6%
603	Subarachnoid Hemorrhage	4.6%
604	Cerebral Arteriosclerosis	4.6%
605	Cerebral Hemorrhage	4.6%
606	Cerebral Thrombosis	4.6%
607	Intracranial Embolism	4.6%
608	Intracranial Thrombosis	4.6%
609	Deafness	4.6%
610	Hearing Loss, Sudden	4.6%
611	Gerstmann Syndrome	4.6%
612	Hearing Loss, Bilateral	4.6%
613	Hearing Loss, High-Frequency	4.6%
614	Hearing Loss, Mixed Conductive-Sensorineural	4.6%
615	Prosopagnosia	4.6%
616	Apraxia, Ideomotor	4.6%
617	Charles Bonnet Syndrome	4.6%
618	Hearing Loss, Unilateral	4.6%
619	Complete Hearing Loss	4.6%
620	Alien Hand Syndrome	4.6%
621	Deaf Mutism	4.6%
622	Amnesia	4.5%
623	Delirium	4.5%
624	Dissociative Amnesia	4.5%
625	Color blindness	4.5%
626	Global Amnesia	4.5%
627	Cri-du-Chat Syndrome	4.5%
628	Down Syndrome	4.5%
629	Brain Diseases, Metabolic, Inborn	4.5%
630	Trisomy 21	4.5%
631	POEMS Syndrome	4.4%
632	Meningioma	4.4%
633	Williams Syndrome	4.4%
634	Microcephaly	4.4%
635	Macrocephaly	4.4%
636	Neurosyphilis	4.4%
637	Hypokalemic periodic paralysis	4.4%
638	Porencephaly	4.4%
639	Mutism	4.3%
640	Selective Mutism	4.3%
641	Acromegaly	4.3%
642	Cerebral Amyloid Angiopathy	4.3%
643	Aicardi's syndrome	4.3%
644	Sinus Thrombosis, Intracranial	4.2%
645	Hoarseness	4.2%
646	Cockayne Syndrome	4.2%
647	Alcohol Withdrawal Delirium	4.2%
648	Alexia, Pure	4.1%
649	Cavernous Sinus Thrombosis	4.1%
650	Sagittal Sinus Thrombosis	4.1%
651	Waterhouse-Friderichsen Syndrome	4%
652	Dermatomyositis	4%
653	Muscular Dystrophy, Duchenne	3.9%
654	Retrograde amnesia	3.8%
655	Amnesia, Anterograde	3.8%
656	Carotid Artery Thrombosis	3.8%
657	Prader-Willi Syndrome	3.8%
658	Menkes Kinky Hair Syndrome	3.8%
659	Wernicke Encephalopathy	3.8%
660	AIDS Dementia Complex	3.8%
661	Phantom pain	3.8%
662	Phantom Limb Pain	3.8%
663	Lyme Neuroborreliosis	3.7%
664	Holoprosencephaly	3.7%
665	Nelson Syndrome	3.4%
666	Kernicterus	3.4%
667	Fragile X Syndrome	3.3%
668	Prolactinoma	3.1%
669	Growth Hormone-Secreting Pituitary Adenoma	3.1%
670	Fabry Disease	3%
671	Rubinstein-Taybi Syndrome	3%
672	Galactosemias	2.9%
673	Urea Cycle Disorders, Inborn	2.9%
674	Tyrosinemias	2.9%
675	Homocystinuria	2.6%
676	Leigh Disease	2.5%
677	Carbamoyl-Phosphate Synthase I Deficiency Disease	2.3%
678	Mucopolysaccharidosis II	2.3%
679	Glycogen storage disease type II	2.1%
680	Zellweger Syndrome	1.9%
681	Gaucher Disease	1.8%
682	Tay-Sachs Disease	1.8%
683	Niemann-Pick Disease, Type C	1.6%

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