MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Anaplastic astrocytoma

(UMLS:C0334579)

UMLS ID:: C0334579
MeSH ID:: D001254

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.465.625.600.380.080|C04.557.470.670.380.080|C04.557.580.625.600.380.080

Synonym(s)

Anaplastic astrocytoma

Anaplastic Astrocytoma

Anaplastic Astrocytoma, NOS

Anaplastic Astrocytoma, Not Otherwise Specified

Astrocytoma malignant

Astrocytoma, anaplastic

Astrocytoma, anaplastic type

Grade III Astrocytic Neoplasm

Grade III Astrocytic Tumor

10.

Grade III Astrocytoma

11.

High-grade astrocytoma, NOS

12.

Malignant Astrocytoma

13.

Malignant astrocytoma

14.

anaplastic astrocytoma

15.

anaplastic astrocytomas

16.

astrocytoma grade iii

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Temozolomide	FAERS: 16 Canada Vigilance: 8	Canada Vigilance OFFSIDES US FAERS
2	Fingolimod Hydrochloride	FAERS: 3	US FAERS
3	Isotretinoin	FAERS: 2	US FAERS
4	Lenalidomide	FAERS: 2	US FAERS
5	Levetiracetam	FAERS: 2	US FAERS
6	Baclofen	FAERS: 1	US FAERS
7	Crizotinib	FAERS: 1	US FAERS
8	Lacosamide	FAERS: 1	US FAERS
9	Methotrexate	FAERS: 1	US FAERS
10	Modafinil	FAERS: 1	US FAERS
11	Thalidomide	FAERS: 1	US FAERS
12	Zoledronic Acid	FAERS: 1	US FAERS
13	paricalcitol	FAERS: 1	OFFSIDES US FAERS
14	Alosenn		OFFSIDES
15	Dacarbazine		OFFSIDES
16	Dactinomycin		OFFSIDES
17	Glycerol		OFFSIDES
18	Hydroxyurea		OFFSIDES
19	Meloxicam		OFFSIDES
20	Tretinoin		OFFSIDES
21	Tropisetron		OFFSIDES
22	sennoside A&B		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Medulloblastoma	57.5%
2	Ependymoma	55.8%
3	oligodendroglioma	55.8%
4	Ganglioglioma	55.8%
5	gliosarcoma	55.8%
6	Anaplastic Oligodendroglioma	55.8%
7	Ganglioneuroma	46%
8	Craniopharyngioma	34.4%
9	Neuroectodermal Tumor, Melanotic	34.4%
10	Neuroendocrine Tumors	34.4%
11	leukemia	31.7%
12	Retinoblastoma	29.5%
13	melanoma	28.7%
14	Optic Nerve Glioma	27%
15	Adenoma, Acidophil	27%
16	Histiocytic Disorders, Malignant	25.5%
17	Adenoma	24.8%
18	Carcinoma	24.8%
19	Epithelioma	24.8%
20	Meningioma	24.6%
21	Chordoma	24%
22	Teratoma	24%
23	Germinoma	24%
24	Teratocarcinoma	24%
25	Trophoblastic Neoplasms	23.5%
26	Carcinoid Tumor	23.5%
27	Neurilemmoma	23%
28	Basal cell carcinoma	22.9%
29	Carcinoma, Papillary	22.9%
30	Squamous cell carcinoma	22.9%
31	Cystadenoma	22.9%
32	Mesothelioma	22.9%
33	Carcinoma, Basal Cell	22.9%
34	Neuroblastoma	22.8%
35	Neoplasms, Germ Cell and Embryonal	21.3%
36	Germ Cell Cancer	21.3%
37	Lymphoma	21.3%
38	Carcinosarcoma	21.2%
39	Hemangiosarcoma	21.2%
40	lymphangiosarcoma	21.2%
41	Hamartoma	21%
42	Neoplasms, Hormone-Dependent	21%
43	Neoplasms, Multiple Primary	21%
44	Paraneoplastic Syndromes	21%
45	Precancerous Conditions	21%
46	Neoplasms, Second Primary	21%
47	Paraganglioma	20.9%
48	Neoplasms, Glandular and Epithelial	20.7%
49	Carcinoma, Ehrlich Tumor	20.1%
50	Carcinoma, Lewis Lung	20.1%
51	Dermoid Cyst	19.5%
52	Composite Lymphoma	19.4%
53	Melanoma, Experimental	19.1%
54	Ganglioneuroblastoma	19%
55	Cystadenocarcinoma	18.7%
56	Mucoepidermoid Carcinoma	18.7%
57	Leukemia, Experimental	18.5%
58	Neuroectodermal Tumors	18.4%
59	Hutchinson's Melanotic Freckle	18.2%
60	Melanoma, Amelanotic	18.2%
61	Leukemia, Plasma Cell	17.6%
62	Carcinoma 256, Walker	17.5%
63	Cyst	17%
64	Neoplastic Processes	17%
65	Neoplastic Syndromes, Hereditary	17%
66	Pregnancy Complications, Neoplastic	17%
67	Ameloblastoma	16.8%
68	Angiokeratoma	16.8%
69	Hemangioma	16.8%
70	hemangiopericytoma	16.8%
71	Lymphangioma	16.8%
72	Mesenchymoma	16.8%
73	Nevus	16.8%
74	Hepatoblastoma	16.8%
75	Mixed Tumor, Mullerian	16.8%
76	Angiofibroma	16.8%
77	Sarcoma	16.8%
78	Neoplasms, Experimental	16.8%
79	Carcinoma, Lobular	16.7%
80	Choriocarcinoma	16.2%
81	Malignant Carcinoid Syndrome	16.2%
82	Neoplasms, Neuroepithelial	16%
83	Gliomatosis cerebri	16%
84	Leukemia, Radiation-Induced	16%
85	Acanthoma	16%
86	Chondrosarcoma	15.3%
87	leiomyosarcoma	15.3%
88	liposarcoma	15.3%
89	synovial sarcoma	15.3%
90	Angiomyolipoma	15.3%
91	Clear Cell Sarcoma of Soft Tissue	15.3%
92	Alveolar Soft Part Sarcoma	15.3%
93	Sarcoma, Myeloid	15.3%
94	Adenofibroma	14.7%
95	Fibroadenoma	14.7%
96	Bowen's Disease	14.6%
97	Adenocarcinoma	14.3%
98	Carcinoma in Situ	14.3%
99	Carcinoma, Transitional Cell	14.3%
100	Papilloma	14.3%
101	Pseudomyxoma Peritonei	14.3%
102	Papillomatosis	14.3%
103	Adenomatosis, Pulmonary	14.3%
104	Adenomatous Polyps	14.3%
105	Carcinoma, Large Cell	14.3%
106	Carcinoma, Small Cell	14.3%
107	Pheochromocytoma	14.2%
108	Neoplasms, Radiation-Induced	14%
109	Multiple Endocrine Neoplasia	13.8%
110	Plasmacytoma	13.5%
111	Sarcoma, Experimental	13.5%
112	Dysgerminoma	13.5%
113	Neuroma	13.5%
114	Seminoma	13.5%
115	Malignant histiocytosis	13.5%
116	Histiocytic sarcoma	13.5%
117	Thymoma	13.4%
118	Endometrial Stromal Sarcoma	12.9%
119	Fibrosarcoma	12.4%
120	Osteosarcoma	12.4%
121	Leukemia L1210	12.2%
122	Leukemia P388	12.2%
123	Hodgkin Disease	11.2%
124	Lymphoma, Non-Hodgkin	11.2%
125	Paraneoplastic Encephalomyelitis	11%
126	Lymphangioleiomyomatosis	11%
127	Malignant Fibrous Histiocytoma	10.9%
128	Carcinoid Heart Disease	10.9%
129	Mammary Neoplasms, Experimental	10.9%
130	Tuberous Sclerosis	10.8%
131	Nephroblastoma	10.8%
132	Abdominal Neoplasms	10.6%
133	Erythroplasia	10.6%
134	Follicular cyst	10.6%
135	Head and Neck Neoplasms	10.6%
136	Mucocele	10.6%
137	Pilonidal Cyst	10.6%
138	Soft Tissue Neoplasms	10.6%
139	Thoracic Neoplasms	10.6%
140	Thyroglossal Cyst	10.6%
141	Synovial Cyst	10.6%
142	Aberrant Crypt Foci	10.6%
143	Basal Cell Nevus Syndrome	10.4%
144	Hepatocellular Adenoma	10.1%
145	Acoustic Neuroma	9.8%
146	Primary amyloidosis	9.7%
147	Phyllodes Tumor	9.5%
148	Glioma	9.5%
149	Hemangioendothelioma	9.5%
150	Lipoma	9.5%
151	Myoma	9.5%
152	Myxoma	9.5%
153	Angiolipoma	9.5%
154	Myelolipoma	9.5%
155	Neoplasms, Bone Tissue	9.5%
156	Neoplasms, Fibrous Tissue	9.5%
157	Smooth Muscle Tumor	9.5%
158	Desmoplastic Small Round Cell Tumor	9.5%
159	Malignant Glioma	9.5%
160	Chondroma	9.5%
161	Enchondroma	9.5%
162	Rhabdomyosarcoma	9.5%
163	Giant Cell Tumor of Bone	9.5%
164	Lymphomatoid Granulomatosis	9.4%
165	Sarcoma 180	9.3%
166	Neurofibrosarcoma	9.2%
167	Adenoid Cystic Carcinoma	9.1%
168	Adenocarcinoma, Clear Cell	9.1%
169	Cholangiocarcinoma	9.1%
170	Cervical Intraepithelial Neoplasia	9.1%
171	neurofibroma	9%
172	Carcinoma, Pancreatic Ductal	8.9%
173	Prolactinoma	8.8%
174	Growth Hormone-Secreting Pituitary Adenoma	8.8%
175	Digestive System Neoplasms	8.8%
176	Endocrine Gland Neoplasms	8.8%
177	Eye Neoplasms	8.8%
178	Nervous System Neoplasms	8.8%
179	Bone neoplasms	8.6%
180	Leukoplakia	8.6%
181	Lymphocele	8.6%
182	Pancreatic Cyst	8.6%
183	Skin Neoplasms	8.6%
184	Hematologic Neoplasms	8.6%
185	Barrett Esophagus	8.5%
186	Breast Cyst	8.5%
187	Actinic keratosis	8.5%
188	Mediastinal Cyst	8.5%
189	Neoplasm Invasiveness	8.5%
190	Neoplasm Metastasis	8.5%
191	Neoplasm Recurrence, Local	8.5%
192	Parovarian Cyst	8.5%
193	Pericardial Cyst	8.5%
194	Splenic Neoplasms	8.5%
195	Thymic Cyst	8.5%
196	Carcinogenesis	8.5%
197	Myxoid cyst	8.5%
198	Metastasis	8.5%
199	Mesoblastic Nephroma	8.3%
200	Dermatofibrosarcoma	8.1%
201	Dermatofibrosarcoma Protuberans	8.1%
202	Carcinoma, Ovarian Epithelial	7.8%
203	Vipoma	7.8%
204	Hydatidiform Mole	7.7%
205	Leukemia, Myelomonocytic, Chronic	7.6%
206	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	7.6%
207	Waldenstrom Macroglobulinemia	7.6%
208	Multiple Myeloma	7.6%
209	Multiple Endocrine Neoplasia Type 1	7.3%
210	Corpus Luteum Cyst	7%
211	Ovarian Cysts	7%
212	Adenomatous Polyposis Coli	7%
213	Liver Neoplasms, Experimental	6.9%
214	Parathyroid Neoplasms	6.6%
215	Peritoneal Neoplasms	6.6%
216	Thyroid Neoplasm	6.6%
217	Thyroid carcinoma	6.6%
218	Alveolar rhabdomyosarcoma	6.6%
219	Mastocytosis	6.5%
220	Sturge-Weber Syndrome	6.5%
221	Klatskin Tumor	6.5%
222	Gastrointestinal Stromal Tumors	6.5%
223	Hemangioma, Cavernous	6.4%
224	Leukemia, T-Cell	6.4%
225	Leukemia, B-Cell	6.4%
226	Lymphoma, Follicular	6.3%
227	T-Cell Lymphoma	6.3%
228	Mantle cell lymphoma	6.3%
229	Astrocytoma	6.3%
230	Anaplastic astrocytoma	6.3%
231	Nasopharyngeal carcinoma	6.3%
232	Choledochal Cyst	6.2%
233	Peutz-Jeghers Syndrome	6%
234	fibroma	5.9%
235	Fibromatosis	5.9%
236	Osteoblastoma	5.9%
237	Osteoma	5.9%
238	Rhabdomyoma	5.9%
239	Chondromatosis	5.9%
240	Hemangioblastoma	5.9%
241	Lymphoma, Extranodal NK-T-Cell	5.9%
242	Pancreatic Neoplasm	5.9%
243	insulinoma	5.8%
244	granulosa cell tumor	5.7%
245	Retroperitoneal Neoplasms	5.6%
246	Adrenocortical carcinoma	5.6%
247	Tracheal Neoplasms	5.2%
248	Leukoplakia, Oral	5.1%
249	Paraneoplastic Cerebellar Degeneration	5.1%
250	Renal Cell Carcinoma	4.9%
251	Papillary Renal Cell Carcinoma	4.9%
252	Mastocytoma	4.8%
253	Mastocytosis, Systemic	4.8%
254	Leukemia, Myeloid, Chronic-Phase	4.7%
255	Glioblastoma	4.7%
256	Glioblastoma Multiforme	4.7%
257	Gastrinoma	4.7%
258	Glucagonoma	4.7%
259	Carcinoma, Endometrioid	4.7%
260	Mouth Neoplasms	4.6%
261	Central Nervous System Neoplasms	4.6%
262	Vascular Neoplasms	4.6%
263	Thymus Neoplasms	4.6%
264	Genital Neoplasms, Female	4.5%
265	Pancreatic Pseudocyst	4.5%
266	Lymphatic Metastasis	4.5%
267	Neoplasms, Unknown Primary	4.5%
268	Leukemic Infiltration	4.5%
269	Breast Neoplasms, Male	4.5%
270	Neoplasm Micrometastasis	4.5%
271	Triple Negative Breast Neoplasms	4.5%
272	Esophageal Neoplasms	4.5%
273	Limbic Encephalitis	4.4%
274	Denys-Drash Syndrome	4.4%
275	Fibromatosis, Aggressive	4.1%
276	Fibromatosis, Abdominal	4.1%
277	Lambert-Eaton Myasthenic Syndrome	4%
278	Testicular Neoplasms	4%
279	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	4%
280	Leukemia, Large Granular Lymphocytic	4%
281	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	4%
282	Lymphoma, T-Cell, Cutaneous	3.9%
283	Lymphoma, AIDS-Related	3.9%
284	Enteropathy-Associated T-Cell Lymphoma	3.9%
285	Primary Effusion Lymphoma	3.9%
286	Xeroderma Pigmentosum	3.9%
287	Adrenal Gland Neoplasms	3.9%
288	Gastrointestinal Neoplasms	3.9%
289	Genital Neoplasms, Male	3.9%
290	Liver neoplasms	3.9%
291	Uveal Neoplasms	3.9%
292	Urologic Neoplasms	3.8%
293	Sebaceous Gland Neoplasms	3.8%
294	Spinal Neoplasms	3.8%
295	Bone Marrow Neoplasms	3.8%
296	Polycystic Ovary Syndrome	3.7%
297	Leydig Cell Tumor	3.7%
298	Thyroid Nodule	3.7%
299	Opsoclonus-Myoclonus Syndrome	3.6%
300	Myelitis, Transverse	3.2%
301	Burkitt Lymphoma	3%
302	ovarian neoplasm	2.9%
303	Dupuytren Contracture	2.8%
304	Urticaria Pigmentosa	2.8%
305	Mycosis Fungoides	2.8%
306	Lymphomatoid Papulosis	2.8%
307	Plasmablastic lymphoma	2.8%
308	Nose Neoplasms	2.7%
309	Meningeal Neoplasms	2.6%
310	Pituitary Adenoma	2.5%
311	Pituitary Neoplasms	2.5%
312	Palatal Neoplasms	2.3%
313	Zollinger-Ellison syndrome	2.3%
314	Ear Neoplasms	2.2%
315	Eyelid Neoplasms	2.2%
316	Lung Neoplasms	2.2%
317	Pleural Neoplasms	2.2%
318	Cell Transformation, Viral	2.2%
319	Brain Neoplasms	2.2%
320	Salivary Gland Neoplasms	2.2%
321	Spinal Cord Neoplasms	2.2%
322	Tongue Neoplasms	2.2%
323	Uterine Neoplasms	2.1%
324	Vaginal Neoplasms	2.1%
325	Vulvar Neoplasms	2.1%
326	Uterine Cancer	2.1%
327	Fallopian Tube Neoplasms	2.1%
328	Sezary Syndrome	2.1%
329	Pharyngeal Neoplasms	1.9%
330	Central Nervous System Cysts	1.9%
331	Bile Duct Neoplasms	1.9%
332	gallbladder neoplasm	1.9%
333	Intestinal Neoplasms	1.9%
334	Penile Neoplasms	1.9%
335	Prostatic Neoplasms	1.9%
336	Stomach Neoplasms	1.9%
337	Polycythemia Vera	1.8%
338	Laryngeal neoplasm	1.7%
339	Bladder Neoplasm	1.6%
340	Kidney Neoplasm	1.6%
341	Ureteral Neoplasms	1.6%
342	Urethral Neoplasms	1.6%
343	Meningeal Carcinomatosis	1.6%
344	Bronchial Neoplasms	1.4%
345	Multiple Pulmonary Nodules	1.3%
346	Supratentorial Neoplasms	1.3%
347	Endometrial Neoplasms	1.3%
348	Hypopharyngeal Neoplasms	1.2%
349	Pleural Effusion, Malignant	1.2%
350	Hypopharyngeal Cancer	1.2%
351	Parotid Neoplasms	1.1%
352	Prostatic Neoplasms, Castration-Resistant	1.1%
353	Nelson Syndrome	1.1%
354	Cecal Neoplasms	1%
355	Duodenal Neoplasms	1%
356	Brain Stem Neoplasms	0.9%
357	Nasopharyngeal Neoplasms	0.9%
358	Colorectal Neoplasms	0.9%
359	Paranasal Sinus Neoplasms	0.8%
360	Tonsillar Neoplasms	0.8%
361	Cerebellar Neoplasms	0.8%
362	Choroid Plexus Papilloma	0.7%
363	Radicular Cyst	0.7%
364	Appendiceal Neoplasms	0.7%
365	Colonic Neoplasms	0.7%
366	Rectal Neoplasms	0.7%
367	Maxillary Sinus Neoplasms	0.6%
368	Anus Neoplasms	0.5%
369	Sigmoid Neoplasms	0.5%

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