MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Melkersson-Rosenthal Syndrome

(UMLS:C0025235)

Definition:: An idiopathic syndrome characterized by one or more of the following; recurrent orofacial swelling, relapsing facial paralysis, and fissured tongue (lingua plicata). The onset is usually in childhood and relapses are common. Cheilitis granulomatosa is a monosymptomatic variant of this condition. (Dermatol Clin 1996 Apr;14(2):371-9; Magalini & Magalini, Dictionary of Medical Syndromes, 4th ed, p531)
UMLS ID:: C0025235
MeSH ID:: D008556

Classification 1:

Name:

Stomatognathic Diseases
MeSH Tree Number(s):: C07.465.299.800|C07.465.466

Classification 2:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.292.319.800

Synonym(s)

Melkersson-Rosenthal Syndrome

Cheilitis granulomatosa of Miescher-Melkersson-Rosenthal

MELKERSSON-ROSENTHAL SYNDROME

Macrocheilia, facial palsy AND edema syndrome

Macrocheilia, facial palsy and edema syndrome

Macrocheilia, facial palsy and oedema syndrome

Melkersson

Melkersson syndrome

Melkersson's syndrome

10.

Melkersson-Rosenthal syndrome

11.

melkerson rosenthal syndrome

12.

melkerson-rosenthal syndrome

13.

melkersson rosenthal syndrome

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Clofazimine	FAERS: 1	US FAERS
2	Methotrexate	FAERS: 1	US FAERS
3	NuvaRing	FAERS: 1	OFFSIDES US FAERS
4	Valsartan	FAERS: 1	US FAERS

Similar ADE(s)

	Name	Semantic Similarity
1	Facial Hemiatrophy	65.9%
2	Bell Palsy	56.3%
3	Facial Neuralgia	50%
4	Trigeminal Nerve Disorder	38%
5	Facial Nerve Injuries	37.1%
6	Burning Mouth Syndrome	36.2%
7	Lip Diseases	36.2%
8	Microglossia	36.2%
9	Oral Submucous Fibrosis	36.2%
10	Periodontal Diseases	36.2%
11	Salivary Gland Diseases	36.2%
12	Stomatitis	36.2%
13	Tongue Diseases	36.2%
14	Oral Ulcer	36.2%
15	Mobius Syndrome	35.9%
16	Herpes Zoster Oticus	35.7%
17	Parotid Neoplasms	33.9%
18	Salivary Gland Fistula	33.5%
19	Salivary Gland Neoplasms	33.5%
20	Tongue Neoplasms	33.5%
21	Mouth Abnormalities	32.2%
22	Trigeminal Neuralgia	32.1%
23	Gingival Recession	32%
24	Parotitis	32%
25	Gingival Atrophy	32%
26	Tooth Loss	30.1%
27	Gingival Hemorrhage	30%
28	Granulomatosis, Orofacial	29.2%
29	Oral candidiasis	28.8%
30	Mouth Neoplasms	28.8%
31	Oral Fistula	28.8%
32	Lichen Planus, Oral	28.5%
33	Facial paralysis	26%
34	Facial Paresis	26%
35	Cheilitis	25.4%
36	Drooling	25.4%
37	Gingival Diseases	25.4%
38	Glossitis	25.4%
39	Macroglossia	25.4%
40	Periodontitis	25.4%
41	Sialadenitis	25.4%
42	Sialometaplasia, Necrotizing	25.4%
43	Sialorrhea	25.4%
44	Aphthous Stomatitis	25.4%
45	Xerostomia	25.4%
46	Glossoptosis	25.4%
47	Peri-Implantitis	25.4%
48	Hemifacial Spasm	25.2%
49	Macrostomia	22.3%
50	Microstomia	22.3%
51	Melkersson-Rosenthal Syndrome	20.5%
52	Gingivitis	20.2%
53	Glossitis, Benign Migratory	20.2%
54	Pericoronitis	20.2%
55	Aggressive Periodontitis	20.2%
56	Gingival Overgrowth	20.2%
57	Dental Fistula	20.1%
58	Oroantral Fistula	20.1%
59	Tooth Diseases	19.6%
60	Giant Cell Epulis	18.5%
61	Gingival Hyperplasia	17.6%
62	Gingival Hypertrophy	17.6%
63	Vesicular Stomatitis	17.3%
64	Radicular Cyst	16.8%
65	Facial Nerve Diseases	16.7%
66	Jaw Diseases	16.2%
67	Pharyngeal Diseases	16.2%
68	Alveolar Bone Loss	16.1%
69	Cleft Palate	15.9%
70	Behcet Syndrome	15.6%
71	Vagus Nerve Disorder	15.5%
72	Glossopharyngeal Neuralgia	15.5%
73	Abducens Nerve Diseases	15.5%
74	Trochlear Nerve Diseases	15.5%
75	Palatal Neoplasms	14.7%
76	Leukoplakia, Oral	14.4%
77	Ocular Motility Disorders	14.3%
78	Cyclophoria	14.3%
79	Herpes Labialis	14.3%
80	Mumps	13.9%
81	Temporomandibular Joint Disorders	12.9%
82	Olfactory Nerve Injuries	12.9%
83	Optic Neuropathy	12.9%
84	Ophthalmoplegic Migraine	12.8%
85	Vestibulocochlear Nerve Diseases	12.3%
86	Bruxism	12.1%
87	Dental Leakage	12.1%
88	Hypercementosis	12.1%
89	Malocclusion	12.1%
90	Tooth Crowding	12.1%
91	Tooth Discoloration	12.1%
92	Tooth Demineralization	12.1%
93	Tooth Ankylosis	12.1%
94	Ulcerative stomatitis	11.7%
95	Dental Enamel Hypoplasia	11.2%
96	Hypodontia	11.2%
97	Toxic Epidermal Necrolysis	11%
98	Stevens-Johnson Syndrome	11%
99	Tooth Injuries	10%
100	Maxillary Diseases	9.7%
101	Tooth Resorption	9.7%
102	Toothache	9.5%
103	Retrognathia	9.2%
104	Jaw Abnormalities	9%
105	Demyelinating Diseases	8.9%
106	Demyelination	8.9%
107	Neuromuscular Diseases	8.9%
108	Chronobiology Disorders	8.9%
109	Sicca Syndrome	8.9%
110	Sjogren's Syndrome	8.9%
111	Dental caries	8.5%
112	Dental Plaque	8.5%
113	Dental Pulp Calcification	8.5%
114	Pulpitis	8.5%
115	Tooth Erosion	8.5%
116	Nasopharyngitis	8.4%
117	Prognathism	8.4%
118	Motor Neuron Disease	8.3%
119	Optic Atrophy	8.2%
120	Optic Neuritis	8.2%
121	Papilledema	8.2%
122	Strabismus	8.2%
123	Tolosa-Hunt Syndrome	8.2%
124	Multiple System Atrophy	8.2%
125	Pharyngitis	8.1%
126	Vestibular Neuronitis	8.1%
127	Miller Fisher Syndrome	7.9%
128	Sleep Bruxism	7.9%
129	Stiff-Person Syndrome	7.8%
130	Temporomandibular Joint Dysfunction Syndrome	7.8%
131	Ophthalmoplegia	7.7%
132	External Ophthalmoplegia	7.7%
133	Opsoclonus-Myoclonus Syndrome	7.7%
134	Progressive supranuclear palsy	7.6%
135	Nasopharyngeal Neoplasms	7.4%
136	Trauma, Nervous System	7.4%
137	Polyradiculoneuropathy	7.3%
138	Polyradiculoneuritis	7.3%
139	Restless Legs Syndrome	7.3%
140	Nervous System Neoplasms	7.1%
141	Neurologic Manifestations	7.1%
142	Neurotoxicity Syndromes	7.1%
143	Neuromyelitis Optica	6.9%
144	Pharyngeal Neoplasms	6.9%
145	Optic Neuropathy, Ischemic	6.9%
146	Anterior Ischemic Optic Neuropathy	6.9%
147	Encephalomyelitis	6.8%
148	Tooth Avulsion	6.8%
149	Prion Diseases	6.8%
150	Autonomic Dysreflexia	6.8%
151	Complex Regional Pain Syndromes	6.8%
152	Vocal Cord Paralysis	6.8%
153	Subacute Combined Degeneration	6.8%
154	Maxillofacial Abnormalities	6.8%
155	Dental Pulp Necrosis	6.8%
156	Spinal Muscular Atrophy	6.7%
157	Progressive Muscular Atrophy	6.7%
158	Amyotrophic Lateral Sclerosis	6.7%
159	Meningoencephalitis	6.7%
160	Acoustic Neuroma	6.6%
161	Micrognathism	6.6%
162	Pierre Robin Syndrome	6.6%
163	Parkinson Disease	6.4%
164	Marchiafava-Bignami Disease	6.1%
165	Lewy Body Disease	6.1%
166	Esotropia	6%
167	Exotropia	6%
168	Guillain-Barre Syndrome	6%
169	Sleep Wake Disorders	6%
170	Striatonigral Degeneration	5.9%
171	Duane Retraction Syndrome	5.9%
172	Spinal Cord Injuries	5.9%
173	Optic Nerve Glioma	5.9%
174	Dandy-Walker Syndrome	5.8%
175	Peripheral Nerve Injuries	5.7%
176	Pneumocephalus	5.7%
177	Poliomyelitis	5.7%
178	Myasthenia Gravis	5.7%
179	Asterixis	5.7%
180	Ballismus	5.7%
181	Tonsillitis	5.6%
182	Leukoencephalitis, Acute Hemorrhagic	5.6%
183	Causalgia	5.6%
184	Myelitis, Transverse	5.4%
185	Myelitis	5.4%
186	Progressive bulbar palsy	5.4%
187	Bulbar palsy	5.4%
188	Lambert-Eaton Myasthenic Syndrome	5.2%
189	Epidural Abscess	5.2%
190	Nasopharyngeal carcinoma	5.2%
191	Lemierre Syndrome	5.2%
192	Shy-Drager Syndrome	5.2%
193	Brain Diseases	5.2%
194	Dysautonomia	5.2%
195	Meningitis	5.2%
196	Movement Disorders	5.2%
197	Pachymeningitis	5.2%
198	Spinal Cord Diseases	5.2%
199	Heavy Metal Poisoning, Nervous System	5.2%
200	Neuromuscular Junction Diseases	5.2%
201	Tauopathies	5.2%
202	Peripheral Nervous System Diseases	5.2%
203	MPTP Poisoning	5.1%
204	Neuroleptic Malignant Syndrome	5.1%
205	Myelinolysis, Central Pontine	5.1%
206	Congenital nystagmus	5.1%
207	Chronic Fatigue Syndrome	5.1%
208	Sleep Disorders, Circadian Rhythm	5%
209	Encephalomyelitis, Acute Disseminated	5%
210	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	5%
211	Dyskinesia, Drug-Induced	4.9%
212	Botulism	4.8%
213	Central Nervous System Cysts	4.8%
214	Retropharyngeal Abscess	4.8%
215	Hypopharyngeal Neoplasms	4.8%
216	Hypopharyngeal Cancer	4.8%
217	Dystonia Musculorum Deformans	4.8%
218	Reflex Sympathetic Dystrophy	4.7%
219	Subdural Effusion	4.7%
220	Parkinsonian Disorders	4.7%
221	Nocturnal Myoclonus Syndrome	4.7%
222	Leukoencephalopathy, Progressive Multifocal	4.5%
223	Brain Injuries	4.5%
224	Brain Neoplasms	4.5%
225	Multiple Sclerosis	4.5%
226	Spinal Cord Neoplasms	4.5%
227	Horner Syndrome	4.3%
228	Central Nervous System Infection	4.3%
229	Myopathy	4.3%
230	Akathisia, Drug-Induced	4.2%
231	Epilepsy, Post-Traumatic	4.2%
232	Craniocerebral Trauma	4.2%
233	Parasomnia	4.2%
234	Dyssomnias	4.2%
235	Limbic Encephalitis	4.1%
236	Huntington Disease	4.1%
237	Decerebrate State	4.1%
238	Hemiparesis	4.1%
239	Hydranencephaly	4.1%
240	Meningism	4.1%
241	Neural Tube Defects	4.1%
242	Paresis	4.1%
243	Seizures	4.1%
244	Sensation Disorders	4.1%
245	Tethered Cord Syndrome	4.1%
246	Central Nervous System Neoplasms	4.1%
247	Complex partial seizures	4.1%
248	Iniencephaly	4.1%
249	Craniorachischisis	4.1%
250	Exencephaly	4.1%
251	Monoparesis	4.1%
252	Septo-Optic Dysplasia	4.1%
253	Cortical Dysplasia	4.1%
254	Neurogenic Inflammation	4.1%
255	Gait Disorders, Neurologic	4.1%
256	Neuromuscular Manifestations	4.1%
257	Malformations of Cortical Development	4.1%
258	Lupus Vasculitis, Central Nervous System	4.1%
259	Sweating, Gustatory	4.1%
260	Auriculotemporal Syndrome	4.1%
261	Myasthenia Gravis, Autoimmune, Experimental	4%
262	Meige Syndrome	4%
263	Brachial Plexus Neuritis	4%
264	Neuralgic Amyotrophy	4%
265	Cerebral Ventriculitis	4%
266	Scrapie	4%
267	Central Cord Syndrome	4%
268	Charcot-Marie-Tooth Disease	3.9%
269	Presenile dementia	3.9%
270	Senile dementia	3.9%
271	Meningitis, Bacterial	3.9%
272	Meningitis, Fungal	3.9%
273	Lafora Disease	3.9%
274	Unverricht-Lundborg Syndrome	3.9%
275	Chorea	3.9%
276	Acrodynia	3.9%
277	Brain Abscess	3.9%
278	Canavan Disease	3.8%
279	Alexander Disease	3.8%
280	Vasculitis, Central Nervous System	3.8%
281	Jet Lag Syndrome	3.8%
282	Peritonsillar Abscess	3.8%
283	Tonsillar Neoplasms	3.8%
284	Cerebellar Neoplasms	3.7%
285	Tuberous Sclerosis	3.7%
286	Dementia, Vascular	3.7%
287	Brain Hemorrhage, Traumatic	3.7%
288	Tarsal Tunnel Syndrome	3.7%
289	Cauda Equina Syndrome	3.7%
290	Posterior Leukoencephalopathy Syndrome	3.7%
291	Posterior reversible encephalopathy syndrome	3.7%
292	Ataxia Telangiectasia	3.6%
293	Pupil Disorders	3.5%
294	Neurobehavioral Manifestations	3.5%
295	Friedreich Ataxia	3.5%
296	Brain Death	3.5%
297	Coma, Post-Head Injury	3.5%
298	Optic Atrophy, Hereditary, Leber	3.5%
299	Paraneoplastic Encephalomyelitis	3.4%
300	Uveomeningoencephalitic Syndrome	3.4%
301	Akinetic Mutism	3.4%
302	Anoxic Encephalopathy	3.4%
303	Arachnoiditis	3.4%
304	Basal Ganglia Diseases	3.4%
305	Brain Damage, Chronic	3.4%
306	Cerebellar Diseases	3.4%
307	Encephalitis	3.4%
308	Encephalomalacia	3.4%
309	Epilepsy	3.4%
310	Hydrocephalus	3.4%
311	Congenital Hydrocephalus	3.4%
312	Hypothalamic Diseases	3.4%
313	Aseptic Meningitis	3.4%
314	Neuritis	3.4%
315	Polyneuritis	3.4%
316	Radiculitis	3.4%
317	Sturge-Weber Syndrome	3.4%
318	Syringomyelia	3.4%
319	Thalamic Diseases	3.4%
320	Vertigo	3.4%
321	Intracranial Hypertension	3.4%
322	Polyneuropathy	3.4%
323	Mononeuritis	3.4%
324	Aura	3.4%
325	Leukoencephalopathy	3.4%
326	Essential Tremor	3.4%
327	Neuroaxonal Dystrophies	3.4%
328	Familial Tremor	3.4%
329	Headache Disorders	3.4%
330	Mononeuropathies	3.4%
331	Intracranial Hypotension	3.4%
332	Brachial Plexus Neuropathies	3.4%
333	Radiculopathy	3.4%
334	Mononeuropathy Multiplex	3.4%
335	Nerve Root Compression	3.4%
336	Alcohol-Induced Disorders, Nervous System	3.4%
337	Brain Edema	3.4%
338	Brain Hypoxia	3.4%
339	Aqueductal Stenosis	3.4%
340	Pneumorrhachis	3.4%
341	Writer's Cramp	3.4%
342	Amblyopia	3.4%
343	Myotonia Congenita	3.3%
344	Creutzfeldt-Jakob disease	3.3%
345	Paraneoplastic Cerebellar Degeneration	3.3%
346	Basal Ganglia Cerebrovascular Disease	3.3%
347	Cerebrospinal Fluid Otorrhea	3.3%
348	Cerebrospinal Fluid Rhinorrhea	3.3%
349	Neuritis, Autoimmune, Experimental	3.3%
350	Brain Injuries, Diffuse	3.3%
351	Traumatic Brain Injury	3.3%
352	Myoclonic Epilepsy	3.3%
353	Epilepsy, Temporal Lobe	3.3%
354	Epilepsy, Rolandic	3.3%
355	Benign Rolandic Epilepsy	3.3%
356	Gait Ataxia	3.3%
357	Cerebellar Ataxia	3.3%
358	Supratentorial Neoplasms	3.3%
359	Torticollis	3.3%
360	Multiple Sclerosis, Chronic Progressive	3.3%
361	Multiple Sclerosis, Relapsing-Remitting	3.3%
362	Carotid Artery Injuries	3.3%
363	Tuberculosis, Meningeal	3.3%
364	Hepatolenticular Degeneration	3.2%
365	Myotonic Dystrophy	3.2%
366	Kearns-Sayre syndrome	3.1%
367	Carpal Tunnel Syndrome	3%
368	Vascular Headaches	3%
369	neurofibroma	3%
370	Hypoxia-Ischemia, Brain	3%
371	Sciatica	3%
372	Tardive Dyskinesia	3%
373	Persistent Vegetative State	3%
374	Alice in Wonderland Syndrome	3%
375	Voice Disorders	3%
376	Juvenile Myoclonic Epilepsy	3%
377	Myoclonic Epilepsies, Progressive	3%
378	Voice Disturbance	3%
379	Alcohol Withdrawal Seizures	2.9%
380	Brain Concussion	2.9%
381	Smith-Magenis syndrome	2.9%
382	Akathisia	2.9%
383	Dural Arteriovenous Fistula	2.9%
384	Restlessness	2.9%
385	Psychomotor Agitation	2.9%
386	Pituitary Adenoma	2.9%
387	Pituitary Neoplasms	2.9%
388	Leukomalacia, Periventricular	2.9%
389	Refsum Disease	2.8%
390	Toxoplasmosis, Cerebral	2.8%
391	Cubital Tunnel Syndrome	2.7%
392	Brain Diseases, Metabolic	2.7%
393	Cerebrovascular Disorders	2.7%
394	Myositis	2.7%
395	Cerebrovascular Insufficiency	2.7%
396	Isaacs syndrome	2.7%
397	Arsenic Poisoning	2.7%
398	Dementia	2.7%
399	Myotonic Disorders	2.7%
400	Central Nervous System Fungal Infections	2.7%
401	Conus Medullaris Syndrome	2.7%
402	Myasthenic Syndromes, Congenital	2.7%
403	Spinal Cord Vascular Diseases	2.7%
404	Diffuse Axonal Injury	2.7%
405	Brain Stem Neoplasms	2.7%
406	Diabetic Neuropathies	2.7%
407	Facial Injuries	2.7%
408	Diabetic Amyotrophy	2.7%
409	Diabetic Autonomic Neuropathy	2.7%
410	Sleep Talking	2.7%
411	Manganese Poisoning	2.7%
412	Sleep Disorders, Intrinsic	2.7%
413	Orthostatic intolerance	2.7%
414	Vertebral Artery Dissection	2.7%
415	Anosmia	2.7%
416	Ataxia	2.7%
417	Athetosis	2.7%
418	Catalepsy	2.7%
419	Dystonia	2.7%
420	Hemiplegia	2.7%
421	Locked-In Syndrome	2.7%
422	Meningeal Neoplasms	2.7%
423	Meningomyelocele	2.7%
424	Muscle Hypertonia	2.7%
425	Muscle hypotonia	2.7%
426	Myoclonus	2.7%
427	Myotonia	2.7%
428	Neuralgia	2.7%
429	Paraplegia	2.7%
430	Pseudobulbar Palsy	2.7%
431	Quadriplegia	2.7%
432	Spasm	2.7%
433	Spastic Paraplegia	2.7%
434	Status Epilepticus	2.7%
435	Taste Disorders	2.7%
436	Tremor	2.7%
437	Spina Bifida	2.7%
438	Monoplegia	2.7%
439	Hypokinesia	2.7%
440	Paraparesis	2.7%
441	Bradykinesia	2.7%
442	Waxy flexibility	2.7%
443	Action Tremor	2.7%
444	Resting Tremor	2.7%
445	Dysosmia	2.7%
446	Quadriparesis	2.7%
447	Mercury Poisoning, Nervous System	2.7%
448	Olfaction Disorders	2.7%
449	Myokymia	2.7%
450	Lead Poisoning, Nervous System	2.7%
451	Somatosensory Disorders	2.7%
452	Neuropathic pain	2.7%
453	Hyperkinesia	2.7%
454	Intention tremor	2.7%
455	Amnesia, Transient Global	2.7%
456	Gait Apraxia	2.7%
457	Basal Ganglia Hemorrhage	2.6%
458	Alstrom Syndrome	2.6%
459	Meningitis, Cryptococcal	2.6%
460	Meningitis, Listeria	2.6%
461	Meningitis, Haemophilus	2.6%
462	Meningitis, Pneumococcal	2.6%
463	Frontotemporal dementia	2.6%
464	Cerebral Palsy	2.5%
465	Epilepsies, Partial	2.5%
466	Epilepsy, Generalized	2.5%
467	Pseudotumor Cerebri	2.5%
468	Sciatic Neuropathy	2.5%
469	Hypertensive Encephalopathy	2.5%
470	Ulnar Neuropathies	2.5%
471	Lesion of Sciatic Nerve	2.5%
472	Simple Partial Seizures	2.5%
473	Epilepsy, Reflex	2.5%
474	Ulnar Neuritis	2.5%
475	Radial nerve compression	2.5%
476	Radial Tunnel Syndrome	2.5%
477	Peroneal Neuropathies	2.5%
478	Radial Neuropathy	2.5%
479	Median Neuropathy	2.5%
480	Sciatic Nerve Palsy	2.5%
481	Femoral Neuropathy	2.5%
482	Tibial Neuropathy	2.5%
483	Ulnar Nerve Palsy	2.5%
484	Postural Orthostatic Tachycardia Syndrome	2.5%
485	Radial nerve palsy	2.5%
486	Headache Disorders, Primary	2.5%
487	Headache Disorders, Secondary	2.5%
488	Medication overuse headache	2.5%
489	Reflex, Abnormal	2.5%
490	Hyporeflexia	2.5%
491	Hyperreflexia	2.5%
492	Mitochondrial Encephalomyopathies	2.5%
493	Choroid Plexus Papilloma	2.5%
494	Subarachnoid Hemorrhage, Traumatic	2.4%
495	Carotid Artery, Internal, Dissection	2.4%
496	Subacute Sclerosing Panencephalitis	2.4%
497	Pituitary Apoplexy	2.4%
498	Putaminal Hemorrhage	2.4%
499	Brain Contusion	2.4%
500	Hand-Arm Vibration Syndrome	2.4%
501	Adrenoleukodystrophy	2.3%
502	Brain Infarction	2.3%
503	Infarction, Middle Cerebral Artery	2.3%
504	Infarction, Anterior Cerebral Artery	2.3%
505	Infarction, Posterior Cerebral Artery	2.3%
506	Vision Disorders	2.3%
507	Metamorphopsia	2.3%
508	Visual Impairment	2.3%
509	Amyloid Neuropathies, Familial	2.3%
510	Fibromyalgia	2.3%
511	Central Nervous System Bacterial Infections	2.3%
512	Medial Tibial Stress Syndrome	2.3%
513	Mitochondrial Myopathies	2.3%
514	Anisocoria	2.3%
515	Confusion	2.3%
516	Lethargy	2.3%
517	Memory Disorders	2.3%
518	Muscle Cramp	2.3%
519	Perceptual Disorders	2.3%
520	Psychomotor Disorders	2.3%
521	Tonic Pupil	2.3%
522	Eosinophilia-Myalgia Syndrome	2.3%
523	Anhedonia	2.3%
524	Disorientation	2.3%
525	Memory Loss	2.3%
526	Hemisensory Neglect	2.3%
527	Dysacusis	2.3%
528	Classical Lissencephalies and Subcortical Band Heterotopias	2.2%
529	Anencephaly	2.2%
530	Meningocele	2.2%
531	Muscular Atrophy	2.2%
532	Respiratory Paralysis	2.2%
533	Encephalocele	2.2%
534	Tetany	2.2%
535	Basal Cell Nevus Syndrome	2.2%
536	Auditory Perceptual Disorders	2.2%
537	Giant Cell Arteritis	2.1%
538	Temporal Arteritis	2.1%
539	Cerebral Infarction	2.1%
540	Pituitary Diseases	2.1%
541	Brain Stem Infarctions	2.1%
542	Polyradiculopathy	2.1%
543	Post-Traumatic Headache	2.1%
544	Tension Headache	2.1%
545	Epilepsy, Complex Partial	2.1%
546	Migraine Disorders	2.1%
547	Abdominal Migraine	2.1%
548	Status Migrainosus	2.1%
549	Cervicogenic Headache	2.1%
550	Alexia	2%
551	Dyslexia	2%
552	Thoracic Outlet Syndrome	2%
553	MELAS Syndrome	2%
554	Carotid Artery Diseases	2%
555	Brain Ischemia	2%
556	Hypotension, Orthostatic	2%
557	Sleep Apnea Syndromes	2%
558	Cerebrovascular accident	2%
559	Polymyositis	2%
560	Kluver-Bucy Syndrome	2%
561	Vasospasm, Intracranial	2%
562	Spinal Cord Ischemia	2%
563	Intracranial Arterial Diseases	2%
564	Post-Exercise Hypotension	2%
565	Disorders of Excessive Somnolence	2%
566	Sleep Initiation and Maintenance Disorders	2%
567	Night Terrors	2%
568	Somnambulism	2%
569	Transient Insomnia	2%
570	Sleep Paralysis	2%
571	Chronic Insomnia	2%
572	REM Sleep Behavior Disorder	2%
573	Hypersomnia	2%
574	Dermal Sinus	2%
575	Dysgeusia	2%
576	Formication	2%
577	Hyperalgesia	2%
578	Hyperesthesia	2%
579	Hypesthesia	2%
580	Language Disorders	2%
581	Numbness	2%
582	Paresthesia	2%
583	Paraparesis, Spastic	2%
584	Spina Bifida Cystica	2%
585	Trismus	2%
586	Spina Bifida Occulta	2%
587	Epilepsia Partialis Continua	2%
588	Hypogeusia	2%
589	Meningeal Carcinomatosis	2%
590	Brown-Sequard Syndrome	2%
591	Lissencephaly	2%
592	Polymicrogyria	2%
593	Pachygyria	2%
594	Schizencephaly	2%
595	Lockjaw	2%
596	Allodynia	2%
597	Lead Poisoning, Nervous System, Childhood	2%
598	Lead Poisoning, Nervous System, Adult	2%
599	Periventricular Nodular Heterotopia	2%
600	Ageusia	2%
601	Tuberculosis, Central Nervous System	2%
602	West Nile Fever	2%
603	Lateral Medullary Syndrome	2%
604	Consciousness Disorders	2%
605	Mental Retardation	2%
606	Muscle Weakness	2%
607	Depressed Level of Consciousness	2%
608	Mental deficiency	2%
609	Intellectual Disability	2%
610	Moyamoya Disease	1.9%
611	Catatonia	1.9%
612	Neurofibrosarcoma	1.9%
613	Familial Periodic Paralysis	1.9%
614	Aphonia	1.9%
615	Sleep Deprivation	1.9%
616	Dysphonia	1.9%
617	Hematoma, Subdural	1.9%
618	Hematoma, Epidural, Cranial	1.9%
619	Cluster Headache	1.9%
620	Migraine with Aura	1.9%
621	Familial Hemiplegic Migraine	1.9%
622	Chronic Paroxysmal Hemicrania	1.9%
623	SUNCT Syndrome	1.9%
624	Paroxysmal Hemicrania	1.9%
625	Eye Injuries	1.7%
626	Empty Sella Syndrome	1.7%
627	Hyperpituitarism	1.7%
628	Hypopituitarism	1.7%
629	Muscular Dystrophy	1.7%
630	Hypophysitis	1.7%
631	Orbital Myositis	1.7%
632	Diplopia	1.7%
633	Muscle Rigidity	1.7%
634	Muscle Spasticity	1.7%
635	Scotoma	1.7%
636	Photophobia	1.7%
637	Cogwheel Rigidity	1.7%
638	Amaurosis	1.7%
639	Blindness	1.7%
640	Nuchal Rigidity	1.7%
641	Reye Syndrome	1.7%
642	Neuroaspergillosis	1.7%
643	Pyomyositis	1.7%
644	Myalgia	1.7%
645	Intracranial Embolism and Thrombosis	1.7%
646	Hepatic Encephalopathy	1.7%
647	Hematoma, Subdural, Intracranial	1.7%
648	Hematoma, Subdural, Chronic	1.7%
649	Hematoma, Subdural, Acute	1.7%
650	Agnosia	1.7%
651	Apraxias	1.7%
652	Hallucinations	1.7%
653	Hemianopsia	1.7%
654	Hyperacusis	1.7%
655	Tinnitus	1.7%
656	Visual Agnosia	1.7%
657	Anosognosia	1.7%
658	Wernicke-Korsakoff Syndrome	1.7%
659	Phonophobia	1.7%
660	Hearing Loss	1.7%
661	Cerebral Arterial Diseases	1.7%
662	Vertebrobasilar Insufficiency	1.7%
663	Anterior Spinal Artery Syndrome	1.7%
664	Basilar Artery Stenosis	1.7%
665	Vertebral Artery Stenosis	1.7%
666	Sleep Apnea, Obstructive	1.7%
667	Sleep Apnea, Central	1.7%
668	Intracranial Hemorrhage, Hypertensive	1.7%
669	Transient Cerebral Ischemia	1.7%
670	Narcolepsy	1.7%
671	Kleine-Levin Syndrome	1.7%
672	Agraphia	1.7%
673	Anomia	1.7%
674	Cluttering	1.7%
675	Language Development Disorders	1.7%
676	Neuronal Ceroid-Lipofuscinoses	1.7%
677	Speech Disorders	1.7%
678	Syncope	1.7%
679	Stupor	1.7%
680	Dysgraphia	1.7%
681	Presyncope	1.7%
682	Sarcopenia	1.7%
683	Dyslalia	1.7%
684	Aicardi's syndrome	1.5%
685	Hyperprolactinemia	1.5%
686	Hoarseness	1.5%
687	Pseudorabies	1.5%
688	Subclavian Steal Syndrome	1.5%
689	Pick Disease of the Brain	1.5%
690	Cockayne Syndrome	1.5%
691	Cataplexy	1.5%
692	Aphasia	1.5%
693	Articulation Disorders	1.5%
694	Echolalia	1.5%
695	Stuttering	1.5%
696	Dysphasia	1.5%
697	Alcohol Withdrawal Delirium	1.5%
698	Amnesia	1.4%
699	Delirium	1.4%
700	Dissociative Amnesia	1.4%
701	Color blindness	1.4%
702	Global Amnesia	1.4%
703	Cri-du-Chat Syndrome	1.4%
704	Down Syndrome	1.4%
705	Brain Diseases, Metabolic, Inborn	1.4%
706	Trisomy 21	1.4%
707	POEMS Syndrome	1.4%
708	Meningioma	1.4%
709	Williams Syndrome	1.4%
710	Microcephaly	1.4%
711	Macrocephaly	1.4%
712	Neurosyphilis	1.4%
713	Hypokalemic periodic paralysis	1.4%
714	Porencephaly	1.4%
715	Toxoplasmosis, Congenital	1.4%
716	Dysarthria	1.4%
717	Eye Burns	1.4%
718	Malaria, Cerebral	1.4%
719	Carotid Stenosis	1.4%
720	Intracranial Aneurysm	1.4%
721	Welander Distal Myopathy	1.4%
722	Neurocysticercosis	1.4%
723	Amaurosis Fugax	1.4%
724	Blindness, Cortical	1.4%
725	Dyscalculia	1.4%
726	Intracranial Arteriosclerosis	1.4%
727	Cerebral Atherosclerosis	1.4%
728	Rett Syndrome	1.4%
729	Subarachnoid Hemorrhage	1.4%
730	Cerebral Arteriosclerosis	1.4%
731	Cerebral Hemorrhage	1.4%
732	Cerebral Thrombosis	1.4%
733	Intracranial Embolism	1.4%
734	Intracranial Thrombosis	1.4%
735	Deafness	1.4%
736	Hearing Loss, Sudden	1.4%
737	Gerstmann Syndrome	1.4%
738	Hearing Loss, Bilateral	1.4%
739	Hearing Loss, High-Frequency	1.4%
740	Hearing Loss, Mixed Conductive-Sensorineural	1.4%
741	Prosopagnosia	1.4%
742	Apraxia, Ideomotor	1.4%
743	Charles Bonnet Syndrome	1.4%
744	Hearing Loss, Unilateral	1.4%
745	Complete Hearing Loss	1.4%
746	Alien Hand Syndrome	1.4%
747	Deaf Mutism	1.4%
748	Holoprosencephaly	1.3%
749	Waterhouse-Friderichsen Syndrome	1.3%
750	Menkes Kinky Hair Syndrome	1.3%
751	Mutism	1.3%
752	Selective Mutism	1.3%
753	Acromegaly	1.3%
754	Prader-Willi Syndrome	1.3%
755	Wernicke Encephalopathy	1.2%
756	AIDS Dementia Complex	1.2%
757	Cerebral Amyloid Angiopathy	1.2%
758	Phantom pain	1.2%
759	Phantom Limb Pain	1.2%
760	Lyme Neuroborreliosis	1.2%
761	Sinus Thrombosis, Intracranial	1.2%
762	Dermatomyositis	1.2%
763	Corneal Scar	1.2%
764	Muscular Dystrophy, Duchenne	1.2%
765	Retrograde amnesia	1.2%
766	Amnesia, Anterograde	1.2%
767	Carotid Artery Thrombosis	1.2%
768	Alexia, Pure	1.2%
769	Cavernous Sinus Thrombosis	1.2%
770	Sagittal Sinus Thrombosis	1.2%
771	Kernicterus	1.1%
772	Corneal Perforation	1.1%
773	Fragile X Syndrome	1%
774	Rubinstein-Taybi Syndrome	1%
775	Nelson Syndrome	1%
776	Fabry Disease	1%
777	Prolactinoma	0.9%
778	Growth Hormone-Secreting Pituitary Adenoma	0.9%
779	Galactosemias	0.9%
780	Urea Cycle Disorders, Inborn	0.9%
781	Tyrosinemias	0.9%
782	Homocystinuria	0.8%
783	Leigh Disease	0.8%
784	Mucopolysaccharidosis II	0.7%
785	Carbamoyl-Phosphate Synthase I Deficiency Disease	0.7%
786	Glycogen storage disease type II	0.7%
787	Zellweger Syndrome	0.6%
788	Gaucher Disease	0.6%
789	Tay-Sachs Disease	0.5%
790	Niemann-Pick Disease, Type C	0.5%

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