MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Neoplasms, Germ Cell and Embryonal

(UMLS:C0027658)

Definition:: Neoplasms composed of primordial GERM CELLS of embryonic GONADS or of elements of the germ layers of the EMBRYO, MAMMALIAN. The concept does not refer to neoplasms located in the gonads or present in an embryo or FETUS.
UMLS ID:: C0027658
MeSH ID:: D009373

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.465

Synonym(s)

Neoplasms, Germ Cell and Embryonal

Associated Drug(s)

	Name	Reference(s)	Data Source
1	BEP protocol	1713639 7538557 21806789	CTD
2	Bleomycin	View details 1690581 2413982 2447295 2472472 2476531 6168223 12078977	CTD
3	Carboplatin	1846407 18643784	CTD
4	Etoposide	2983893 18643784	CTD
5	ICE protocol 3	9404920	CTD
6	Ifosfamide	1846407 17593098 18643784	CTD
7	Paclitaxel	17593098	CTD
8	Vinblastine	View details 1690581 2413982 2447295 2472472 2476531 6168223 12078977	CTD
9	nedaplatin	17593098	CTD
10	palbociclib	25522918	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	leukemia	42.9%
2	Neoplasms, Glandular and Epithelial	42.9%
3	Carcinosarcoma	37.1%
4	Hemangiosarcoma	37.1%
5	lymphangiosarcoma	37.1%
6	Basal cell carcinoma	33.3%
7	Carcinoma, Papillary	33.3%
8	Squamous cell carcinoma	33.3%
9	Chondrosarcoma	33.3%
10	Cystadenoma	33.3%
11	leiomyosarcoma	33.3%
12	liposarcoma	33.3%
13	Mesothelioma	33.3%
14	synovial sarcoma	33.3%
15	Angiomyolipoma	33.3%
16	Clear Cell Sarcoma of Soft Tissue	33.3%
17	Alveolar Soft Part Sarcoma	33.3%
18	Sarcoma, Myeloid	33.3%
19	Carcinoma, Basal Cell	33.3%
20	Cystadenocarcinoma	31.5%
21	Fibrosarcoma	31.5%
22	Osteosarcoma	31.5%
23	Mucoepidermoid Carcinoma	31.5%
24	Adenoma	31%
25	Ameloblastoma	31%
26	Angiokeratoma	31%
27	Carcinoma	31%
28	Hemangioma	31%
29	hemangiopericytoma	31%
30	Lymphangioma	31%
31	Mesenchymoma	31%
32	Nevus	31%
33	Hepatoblastoma	31%
34	Mixed Tumor, Mullerian	31%
35	Angiofibroma	31%
36	Sarcoma	31%
37	Epithelioma	31%
38	Carcinoma 256, Walker	30.8%
39	Adenofibroma	30.6%
40	Fibroadenoma	30.6%
41	Malignant Fibrous Histiocytoma	30.6%
42	Bowen's Disease	29.7%
43	Rhabdomyosarcoma	29.7%
44	Giant Cell Tumor of Bone	29.7%
45	Dermatofibrosarcoma	28.8%
46	Dermatofibrosarcoma Protuberans	28.8%
47	Histiocytic Disorders, Malignant	27.9%
48	Alveolar rhabdomyosarcoma	27.9%
49	Leukemia, Plasma Cell	27.5%
50	Neoplasms, Neuroepithelial	27.5%
51	Gliomatosis cerebri	27.5%
52	Meningioma	26.9%
53	Carcinoma, Ehrlich Tumor	26.4%
54	Carcinoma, Lewis Lung	26.4%
55	melanoma	26%
56	Adenocarcinoma	25.4%
57	Carcinoma in Situ	25.4%
58	Carcinoma, Transitional Cell	25.4%
59	Phyllodes Tumor	25.4%
60	Hemangioendothelioma	25.4%
61	Lipoma	25.4%
62	Myoma	25.4%
63	Myxoma	25.4%
64	Neuroma	25.4%
65	Papilloma	25.4%
66	Pseudomyxoma Peritonei	25.4%
67	Papillomatosis	25.4%
68	Angiolipoma	25.4%
69	Myelolipoma	25.4%
70	Neoplasms, Bone Tissue	25.4%
71	Neoplasms, Fibrous Tissue	25.4%
72	Smooth Muscle Tumor	25.4%
73	Adenomatosis, Pulmonary	25.4%
74	Adenomatous Polyps	25.4%
75	Carcinoma, Large Cell	25.4%
76	Carcinoma, Small Cell	25.4%
77	Desmoplastic Small Round Cell Tumor	25.4%
78	Chondroma	25.4%
79	Enchondroma	25.4%
80	Medulloblastoma	24.1%
81	Composite Lymphoma	24%
82	Leukemia L1210	23.6%
83	Leukemia P388	23.6%
84	Acanthoma	23.6%
85	Adenoma, Acidophil	23.4%
86	Ganglioneuroma	23.4%
87	Glioma	23.4%
88	Malignant Glioma	23.4%
89	Hamartoma	23.1%
90	Neoplasms, Hormone-Dependent	23.1%
91	Neoplasms, Multiple Primary	23.1%
92	Paraneoplastic Syndromes	23.1%
93	Precancerous Conditions	23.1%
94	Neoplasms, Second Primary	23.1%
95	Carcinoma, Lobular	22.8%
96	Adenoid Cystic Carcinoma	22.7%
97	fibroma	22.7%
98	Fibromatosis	22.7%
99	Osteoblastoma	22.7%
100	Osteoma	22.7%
101	Rhabdomyoma	22.7%
102	Chondromatosis	22.7%
103	Adenocarcinoma, Clear Cell	22.7%
104	Cholangiocarcinoma	22.7%
105	Cervical Intraepithelial Neoplasia	22.7%
106	Hemangioblastoma	22.7%
107	Lymphoma, Extranodal NK-T-Cell	22.7%
108	Hutchinson's Melanotic Freckle	22.7%
109	Melanoma, Amelanotic	22.7%
110	Leukemia, Experimental	22.2%
111	Carcinoid Tumor	22%
112	Neurilemmoma	22%
113	Sarcoma 180	21.8%
114	Neurofibrosarcoma	21.4%
115	Astrocytoma	21.3%
116	Ependymoma	21.3%
117	oligodendroglioma	21.3%
118	Ganglioglioma	21.3%
119	gliosarcoma	21.3%
120	Anaplastic astrocytoma	21.3%
121	Anaplastic Oligodendroglioma	21.3%
122	Fibromatosis, Aggressive	21.3%
123	Fibromatosis, Abdominal	21.3%
124	Klatskin Tumor	21.3%
125	Lymphoma	20.7%
126	Malignant Carcinoid Syndrome	20.7%
127	Endometrial Stromal Sarcoma	20.6%
128	Plasmacytoma	20.5%
129	Neuroectodermal Tumors	20.5%
130	Glioblastoma	20.3%
131	Neuroblastoma	20.3%
132	Glioblastoma Multiforme	20.3%
133	Malignant histiocytosis	20.2%
134	Histiocytic sarcoma	20.2%
135	Ganglioneuroblastoma	19.8%
136	Lymphangioleiomyomatosis	19.7%
137	Melanoma, Experimental	19.7%
138	Sarcoma, Experimental	19.5%
139	Thymoma	19.3%
140	Leukemia, Radiation-Induced	17.9%
141	Craniopharyngioma	16.7%
142	Leukemia, Myelomonocytic, Chronic	16.7%
143	Neuroectodermal Tumor, Melanotic	16.7%
144	Neuroendocrine Tumors	16.7%
145	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	16.7%
146	Carcinoid Heart Disease	16.3%
147	Mastocytoma	15.1%
148	Cyst	15%
149	Hodgkin Disease	15%
150	Lymphoma, Non-Hodgkin	15%
151	Neoplastic Processes	15%
152	Neoplastic Syndromes, Hereditary	15%
153	Pregnancy Complications, Neoplastic	15%
154	Mastocytosis, Systemic	14.9%
155	Carcinoma, Pancreatic Ductal	14.9%
156	Leukemia, Myeloid, Chronic-Phase	14.8%
157	Paraganglioma	14.8%
158	Neoplasms, Experimental	14.6%
159	Abdominal Neoplasms	14.3%
160	Erythroplasia	14.3%
161	Follicular cyst	14.3%
162	Head and Neck Neoplasms	14.3%
163	Mucocele	14.3%
164	Pilonidal Cyst	14.3%
165	Soft Tissue Neoplasms	14.3%
166	Thoracic Neoplasms	14.3%
167	Thyroglossal Cyst	14.3%
168	Synovial Cyst	14.3%
169	Aberrant Crypt Foci	14.3%
170	Lymphomatoid Granulomatosis	14.2%
171	Pheochromocytoma	13.9%
172	Retinoblastoma	13.9%
173	Hepatocellular Adenoma	13.3%
174	Basal Cell Nevus Syndrome	13.1%
175	Choriocarcinoma	12.9%
176	Mastocytosis	12.8%
177	Sturge-Weber Syndrome	12.8%
178	Multiple Endocrine Neoplasia	12.8%
179	Gastrointestinal Stromal Tumors	12.6%
180	Hemangioma, Cavernous	12.5%
181	Leukemia, T-Cell	12.4%
182	Leukemia, B-Cell	12.4%
183	neurofibroma	12.3%
184	Lymphoma, Follicular	12.3%
185	T-Cell Lymphoma	12.3%
186	Mantle cell lymphoma	12.3%
187	Paraneoplastic Encephalomyelitis	12.3%
188	Primary amyloidosis	12.1%
189	Mammary Neoplasms, Experimental	12%
190	Acoustic Neuroma	11.5%
191	Nephroblastoma	11.2%
192	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	11%
193	Leukemia, Large Granular Lymphocytic	11%
194	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	11%
195	Prolactinoma	11%
196	Growth Hormone-Secreting Pituitary Adenoma	11%
197	Lymphoma, T-Cell, Cutaneous	11%
198	Lymphoma, AIDS-Related	11%
199	Enteropathy-Associated T-Cell Lymphoma	11%
200	Primary Effusion Lymphoma	11%
201	Dupuytren Contracture	10.8%
202	Neoplasms, Radiation-Induced	10.8%
203	Urticaria Pigmentosa	10.6%
204	Mesoblastic Nephroma	10.5%
205	insulinoma	10.4%
206	Retroperitoneal Neoplasms	10.3%
207	Mycosis Fungoides	10.3%
208	Lymphomatoid Papulosis	10.3%
209	Plasmablastic lymphoma	10.3%
210	Optic Nerve Glioma	10.3%
211	Gastrinoma	10.1%
212	Glucagonoma	10.1%
213	Digestive System Neoplasms	10%
214	Endocrine Gland Neoplasms	10%
215	Eye Neoplasms	10%
216	Nervous System Neoplasms	10%
217	Adrenocortical carcinoma	9.8%
218	Bone neoplasms	9.5%
219	Leukoplakia	9.5%
220	Lymphocele	9.5%
221	Pancreatic Cyst	9.5%
222	Skin Neoplasms	9.5%
223	Hematologic Neoplasms	9.5%
224	Multiple Endocrine Neoplasia Type 1	9.4%
225	granulosa cell tumor	9.3%
226	Carcinoma, Ovarian Epithelial	9.3%
227	Barrett Esophagus	9.3%
228	Breast Cyst	9.3%
229	Actinic keratosis	9.3%
230	Mediastinal Cyst	9.3%
231	Neoplasm Invasiveness	9.3%
232	Neoplasm Metastasis	9.3%
233	Neoplasm Recurrence, Local	9.3%
234	Parovarian Cyst	9.3%
235	Pericardial Cyst	9.3%
236	Splenic Neoplasms	9.3%
237	Thymic Cyst	9.3%
238	Carcinogenesis	9.3%
239	Myxoid cyst	9.3%
240	Metastasis	9.3%
241	Dermoid Cyst	9.2%
242	Leydig Cell Tumor	9%
243	Vipoma	8.8%
244	Waldenstrom Macroglobulinemia	8.6%
245	Multiple Myeloma	8.6%
246	Adenomatous Polyposis Coli	8.4%
247	Renal Cell Carcinoma	8.3%
248	Parathyroid Neoplasms	8.3%
249	Peritoneal Neoplasms	8.3%
250	Thyroid Neoplasm	8.3%
251	Thyroid carcinoma	8.3%
252	Papillary Renal Cell Carcinoma	8.3%
253	Tuberous Sclerosis	8.2%
254	Carcinoma, Endometrioid	8.2%
255	Nasopharyngeal carcinoma	7.8%
256	Tracheal Neoplasms	7.6%
257	Leukoplakia, Oral	7.4%
258	Burkitt Lymphoma	7.3%
259	Paraneoplastic Cerebellar Degeneration	7.3%
260	Liver Neoplasms, Experimental	7.3%
261	Mouth Neoplasms	7%
262	Pancreatic Neoplasm	7%
263	Central Nervous System Neoplasms	7%
264	Vascular Neoplasms	7%
265	Thymus Neoplasms	7%
266	Sezary Syndrome	6.9%
267	Trophoblastic Neoplasms	6.9%
268	Genital Neoplasms, Female	6.8%
269	Pancreatic Pseudocyst	6.8%
270	Corpus Luteum Cyst	6.8%
271	Ovarian Cysts	6.8%
272	Lymphatic Metastasis	6.7%
273	Neoplasms, Unknown Primary	6.7%
274	Leukemic Infiltration	6.7%
275	Breast Neoplasms, Male	6.7%
276	Neoplasm Micrometastasis	6.7%
277	Triple Negative Breast Neoplasms	6.7%
278	Thyroid Nodule	6.7%
279	Denys-Drash Syndrome	6.3%
280	Esophageal Neoplasms	6.1%
281	Limbic Encephalitis	6.1%
282	Meningeal Neoplasms	5.6%
283	Choledochal Cyst	5.6%
284	Peutz-Jeghers Syndrome	5.4%
285	Lambert-Eaton Myasthenic Syndrome	5.3%
286	Testicular Neoplasms	5.3%
287	Adrenal Gland Neoplasms	5.3%
288	Gastrointestinal Neoplasms	5.3%
289	Genital Neoplasms, Male	5.3%
290	Liver neoplasms	5.3%
291	Uveal Neoplasms	5.3%
292	Urologic Neoplasms	5.2%
293	Sebaceous Gland Neoplasms	5.1%
294	Spinal Neoplasms	5.1%
295	Bone Marrow Neoplasms	5.1%
296	Meningeal Carcinomatosis	5%
297	Polycystic Ovary Syndrome	5%
298	Opsoclonus-Myoclonus Syndrome	4.6%
299	Palatal Neoplasms	4.5%
300	Ear Neoplasms	4.3%
301	Eyelid Neoplasms	4.3%
302	Lung Neoplasms	4.3%
303	Pleural Neoplasms	4.3%
304	Nose Neoplasms	4.3%
305	Cell Transformation, Viral	4.2%
306	Brain Neoplasms	4.2%
307	Salivary Gland Neoplasms	4.2%
308	Spinal Cord Neoplasms	4.2%
309	Tongue Neoplasms	4.2%
310	Uterine Neoplasms	4.1%
311	Vaginal Neoplasms	4.1%
312	Vulvar Neoplasms	4.1%
313	Uterine Cancer	4.1%
314	Fallopian Tube Neoplasms	4.1%
315	Hydatidiform Mole	4.1%
316	Myelitis, Transverse	4%
317	Bronchial Neoplasms	3.8%
318	Multiple Pulmonary Nodules	3.8%
319	Pituitary Adenoma	3.7%
320	Pituitary Neoplasms	3.7%
321	Supratentorial Neoplasms	3.7%
322	Endometrial Neoplasms	3.7%
323	Pharyngeal Neoplasms	3.5%
324	Brain Stem Neoplasms	3.5%
325	Central Nervous System Cysts	3.4%
326	ovarian neoplasm	3.4%
327	Bile Duct Neoplasms	3.4%
328	gallbladder neoplasm	3.4%
329	Intestinal Neoplasms	3.4%
330	Penile Neoplasms	3.4%
331	Prostatic Neoplasms	3.4%
332	Stomach Neoplasms	3.4%
333	Choroid Plexus Papilloma	3.3%
334	Polycythemia Vera	3.3%
335	Hypopharyngeal Neoplasms	3%
336	Pleural Effusion, Malignant	3%
337	Hypopharyngeal Cancer	3%
338	Xeroderma Pigmentosum	3%
339	Parotid Neoplasms	3%
340	Prostatic Neoplasms, Castration-Resistant	3%
341	Nelson Syndrome	2.9%
342	Laryngeal neoplasm	2.9%
343	Tonsillar Neoplasms	2.8%
344	Cerebellar Neoplasms	2.8%
345	Bladder Neoplasm	2.8%
346	Kidney Neoplasm	2.8%
347	Ureteral Neoplasms	2.8%
348	Urethral Neoplasms	2.8%
349	Zollinger-Ellison syndrome	2.5%
350	Cecal Neoplasms	2.5%
351	Duodenal Neoplasms	2.5%
352	Radicular Cyst	2.3%
353	Appendiceal Neoplasms	2.3%
354	Colonic Neoplasms	2.3%
355	Rectal Neoplasms	2.3%
356	Nasopharyngeal Neoplasms	2.1%
357	Colorectal Neoplasms	2.1%
358	Anus Neoplasms	1.9%
359	Sigmoid Neoplasms	1.9%
360	Paranasal Sinus Neoplasms	1.9%
361	Maxillary Sinus Neoplasms	1.7%

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