MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Marchiafava-Bignami Disease

(UMLS:C0238265)

Definition:: A neurodegenerative condition that is characterized by demyelination or necrosis of the CORPUS CALLOSUM. Symptoms include DEPRESSION; PARANOIA; DEMENTIA; SEIZURES; and ATAXIA which can progress to COMA and death in a few months. Marchiafava-Bignami syndrome is seen often in alcoholics but has been found in non-alcoholics as well.
UMLS ID:: C0238265
MeSH ID:: D054319

Classification:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.140.163.510|C10.314.475

Synonym(s)

Marchiafava-Bignami Disease

Callosum degeneration syndrome

Central demyelination of corpus callosum

ENCEPHALOPATHY, CALLOSAL DEMYELINATING

MARCHIAFAVA DISEASE

Marchiafava

Marchiafava Bignami disease

Marchiafava disease

Marchiafava-Bignami disease

10.

central demyelination of corpus callosum

11.

corpus callosum; demyelination

12.

demyelination; corpus callosum

13.

encephalopathy; demyelinating callosal

14.

marchiafava disease

15.

marchiafava-bignami disease

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Rivaroxaban	FAERS: 1		US FAERS
2	Alcohols		25307574	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Myelinolysis, Central Pontine	43.2%
2	Meningoencephalitis	33.1%
3	Encephalomyelitis	32.5%
4	Subdural Effusion	31.7%
5	Multiple System Atrophy	31.5%
6	Akinetic Mutism	30.3%
7	Anoxic Encephalopathy	30.3%
8	Basal Ganglia Diseases	30.3%
9	Brain Damage, Chronic	30.3%
10	Cerebellar Diseases	30.3%
11	Encephalitis	30.3%
12	Encephalomalacia	30.3%
13	Epilepsy	30.3%
14	Hydrocephalus	30.3%
15	Congenital Hydrocephalus	30.3%
16	Hypothalamic Diseases	30.3%
17	Thalamic Diseases	30.3%
18	Intracranial Hypertension	30.3%
19	Aura	30.3%
20	Leukoencephalopathy	30.3%
21	Neuroaxonal Dystrophies	30.3%
22	Headache Disorders	30.3%
23	Intracranial Hypotension	30.3%
24	Brain Edema	30.3%
25	Brain Hypoxia	30.3%
26	Aqueductal Stenosis	30.3%
27	Dandy-Walker Syndrome	28.5%
28	Parkinsonian Disorders	28.3%
29	Posterior Leukoencephalopathy Syndrome	28%
30	Posterior reversible encephalopathy syndrome	28%
31	Polyradiculoneuropathy	27.8%
32	Polyradiculoneuritis	27.8%
33	Lewy Body Disease	27.6%
34	Subacute Combined Degeneration	27.6%
35	Pneumocephalus	27.2%
36	Leukoencephalitis, Acute Hemorrhagic	26.7%
37	Meningitis	26.4%
38	Movement Disorders	26.4%
39	Pachymeningitis	26.4%
40	Spinal Cord Diseases	26.4%
41	Parkinson Disease	26.1%
42	Ocular Motility Disorders	25.9%
43	Cyclophoria	25.9%
44	Ophthalmoplegic Migraine	25.5%
45	Cranial nerve diseases	25.3%
46	Neuromuscular Diseases	25.3%
47	Chronobiology Disorders	25.3%
48	Dementia, Vascular	25.3%
49	Myelitis	25.2%
50	Basal Ganglia Cerebrovascular Disease	25.2%
51	Encephalomyelitis, Acute Disseminated	24.8%
52	Meige Syndrome	24.8%
53	Cerebral Ventriculitis	24.8%
54	Myoclonic Epilepsy	24.6%
55	Epilepsy, Temporal Lobe	24.6%
56	Epilepsy, Post-Traumatic	24.6%
57	Epilepsy, Rolandic	24.6%
58	Benign Rolandic Epilepsy	24.6%
59	Brain Injuries	24.2%
60	Leukoencephalopathy, Progressive Multifocal	24%
61	Brain Neoplasms	24%
62	Prion Diseases	23.9%
63	Brain Abscess	23.6%
64	Stiff-Person Syndrome	23.4%
65	Reye Syndrome	23.3%
66	Hepatic Encephalopathy	23.2%
67	Cerebrovascular Disorders	23.1%
68	Cerebrovascular Insufficiency	23.1%
69	Dementia	23.1%
70	Striatonigral Degeneration	23%
71	Epidural Abscess	22.7%
72	Motor Neuron Disease	22.6%
73	Vascular Headaches	22.4%
74	Hypoxia-Ischemia, Brain	22.3%
75	Canavan Disease	22.2%
76	Alexander Disease	22.2%
77	Spinal Muscular Atrophy	22.1%
78	Progressive Muscular Atrophy	22.1%
79	Cerebellar Neoplasms	21.7%
80	Neuroleptic Malignant Syndrome	21.6%
81	Brain Death	21.6%
82	Dystonia Musculorum Deformans	21.5%
83	Guillain-Barre Syndrome	21.3%
84	Juvenile Myoclonic Epilepsy	21.2%
85	Myoclonic Epilepsies, Progressive	21.2%
86	Miller Fisher Syndrome	21.2%
87	Cerebral Palsy	21.1%
88	Epilepsies, Partial	21.1%
89	Epilepsy, Generalized	21.1%
90	Pseudotumor Cerebri	21.1%
91	Hypertensive Encephalopathy	21.1%
92	Simple Partial Seizures	21.1%
93	Epilepsy, Reflex	21.1%
94	Headache Disorders, Primary	21.1%
95	Headache Disorders, Secondary	21.1%
96	Medication overuse headache	21.1%
97	Leukomalacia, Periventricular	21%
98	Progressive supranuclear palsy	20.8%
99	Central Nervous System Infection	20.7%
100	Huntington Disease	20.6%
101	Myelitis, Transverse	20.1%
102	Neuromyelitis Optica	20%
103	Amyotrophic Lateral Sclerosis	20%
104	Multiple Sclerosis	20%
105	Creutzfeldt-Jakob disease	19.9%
106	Spinal Cord Injuries	19.9%
107	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	19.8%
108	Mitochondrial Encephalomyopathies	19.8%
109	Shy-Drager Syndrome	19.8%
110	Trauma, Nervous System	19.6%
111	Poliomyelitis	19.4%
112	Brain Diseases, Metabolic, Inborn	19.4%
113	MPTP Poisoning	19.4%
114	Asterixis	19%
115	Ballismus	19%
116	Amblyopia	18.9%
117	Nervous System Neoplasms	18.9%
118	Neurologic Manifestations	18.9%
119	Neurotoxicity Syndromes	18.9%
120	Autonomic Dysreflexia	18.8%
121	Complex Regional Pain Syndromes	18.8%
122	Presenile dementia	18.7%
123	Senile dementia	18.7%
124	Limbic Encephalitis	18.4%
125	Lafora Disease	18.1%
126	Unverricht-Lundborg Syndrome	18.1%
127	Restless Legs Syndrome	18%
128	Hepatolenticular Degeneration	17.7%
129	Lupus Vasculitis, Central Nervous System	17.6%
130	Basal Ganglia Hemorrhage	17.4%
131	Meningitis, Bacterial	17.3%
132	Meningitis, Fungal	17.3%
133	Brain Injuries, Diffuse	17.1%
134	Traumatic Brain Injury	17.1%
135	Cerebellar Ataxia	17%
136	Supratentorial Neoplasms	17%
137	Arachnoiditis	16.9%
138	Aseptic Meningitis	16.9%
139	Syringomyelia	16.9%
140	Essential Tremor	16.9%
141	Familial Tremor	16.9%
142	Pneumorrhachis	16.9%
143	Writer's Cramp	16.9%
144	Pituitary Diseases	16.7%
145	Brain Hemorrhage, Traumatic	16.6%
146	Pituitary Apoplexy	16.6%
147	Post-Traumatic Headache	16.6%
148	Tension Headache	16.6%
149	Epilepsy, Complex Partial	16.6%
150	Migraine Disorders	16.6%
151	Abdominal Migraine	16.6%
152	Status Migrainosus	16.6%
153	Cervicogenic Headache	16.6%
154	Chronic Fatigue Syndrome	16.6%
155	Adrenoleukodystrophy	16.5%
156	Wernicke Encephalopathy	16.5%
157	Persistent Vegetative State	16.3%
158	Brain Infarction	16.3%
159	Spinal Cord Neoplasms	16%
160	Pituitary Adenoma	16%
161	Pituitary Neoplasms	16%
162	Carotid Artery Injuries	16%
163	Carotid Artery Diseases	15.8%
164	Brain Ischemia	15.8%
165	Cerebrovascular accident	15.8%
166	Kluver-Bucy Syndrome	15.8%
167	Vasospasm, Intracranial	15.8%
168	Intracranial Arterial Diseases	15.8%
169	Multiple Sclerosis, Chronic Progressive	15.7%
170	Multiple Sclerosis, Relapsing-Remitting	15.7%
171	Amnesia, Transient Global	15.5%
172	Paraneoplastic Cerebellar Degeneration	15.5%
173	Friedreich Ataxia	15.5%
174	Vasculitis, Central Nervous System	15.4%
175	Sleep Wake Disorders	15.3%
176	Putaminal Hemorrhage	15.2%
177	Causalgia	15.2%
178	Peripheral Nerve Injuries	15.2%
179	Progressive bulbar palsy	15.1%
180	Bulbar palsy	15.1%
181	Myasthenia Gravis	15%
182	Dysautonomia	14.9%
183	Vagus Nerve Disorder	14.9%
184	Glossopharyngeal Neuralgia	14.9%
185	Abducens Nerve Diseases	14.9%
186	Heavy Metal Poisoning, Nervous System	14.9%
187	Neuromuscular Junction Diseases	14.9%
188	Tauopathies	14.9%
189	Trochlear Nerve Diseases	14.9%
190	Peripheral Nervous System Diseases	14.9%
191	Opsoclonus-Myoclonus Syndrome	14.9%
192	Infarction, Middle Cerebral Artery	14.8%
193	Infarction, Anterior Cerebral Artery	14.8%
194	Infarction, Posterior Cerebral Artery	14.8%
195	Kernicterus	14.7%
196	Cluster Headache	14.3%
197	Migraine with Aura	14.3%
198	Familial Hemiplegic Migraine	14.3%
199	Chronic Paroxysmal Hemicrania	14.3%
200	SUNCT Syndrome	14.3%
201	Paroxysmal Hemicrania	14.3%
202	Toxoplasmosis, Cerebral	14.2%
203	MELAS Syndrome	14.1%
204	Cerebral Infarction	14%
205	Brain Stem Infarctions	14%
206	Dyskinesia, Drug-Induced	13.9%
207	Olfactory Nerve Injuries	13.8%
208	Diffuse Axonal Injury	13.7%
209	Brain Stem Neoplasms	13.7%
210	Akathisia, Drug-Induced	13.6%
211	Scrapie	13.5%
212	Central Cord Syndrome	13.5%
213	Tuberculosis, Meningeal	13.4%
214	Reflex Sympathetic Dystrophy	13.3%
215	Nocturnal Myoclonus Syndrome	13.3%
216	Chorea	13.2%
217	Moyamoya Disease	13%
218	Lambert-Eaton Myasthenic Syndrome	13%
219	Lateral Medullary Syndrome	12.9%
220	Sleep Disorders, Circadian Rhythm	12.9%
221	Central Nervous System Fungal Infections	12.8%
222	Conus Medullaris Syndrome	12.8%
223	Spinal Cord Vascular Diseases	12.8%
224	Empty Sella Syndrome	12.7%
225	Hyperpituitarism	12.7%
226	Hypopituitarism	12.7%
227	Hypophysitis	12.7%
228	Intracranial Embolism and Thrombosis	12.6%
229	Botulism	12.4%
230	Central Nervous System Cysts	12.4%
231	Cerebral Arterial Diseases	12.3%
232	Vertebrobasilar Insufficiency	12.3%
233	Basilar Artery Stenosis	12.3%
234	Vertebral Artery Stenosis	12.3%
235	Intracranial Hemorrhage, Hypertensive	12.3%
236	Transient Cerebral Ischemia	12.3%
237	Refsum Disease	12.2%
238	Choroid Plexus Papilloma	12%
239	Frontotemporal dementia	12%
240	Subarachnoid Hemorrhage, Traumatic	11.8%
241	Carotid Artery, Internal, Dissection	11.8%
242	Facial Nerve Injuries	11.8%
243	Ataxia Telangiectasia	11.8%
244	Torticollis	11.8%
245	Myopathy	11.7%
246	Optic Neuropathy	11.7%
247	Brachial Plexus Neuritis	11.6%
248	Neuralgic Amyotrophy	11.6%
249	Brain Contusion	11.4%
250	Subacute Sclerosing Panencephalitis	11.4%
251	Brain Concussion	11.4%
252	Facial Nerve Diseases	11.3%
253	Craniocerebral Trauma	11.3%
254	Parasomnia	11.3%
255	Dyssomnias	11.3%
256	Vertebral Artery Dissection	11.3%
257	Horner Syndrome	11.1%
258	Vestibulocochlear Nerve Diseases	11.1%
259	Decerebrate State	11.1%
260	Hemiparesis	11.1%
261	Hydranencephaly	11.1%
262	Meningism	11.1%
263	Neural Tube Defects	11.1%
264	Paresis	11.1%
265	Seizures	11.1%
266	Sensation Disorders	11.1%
267	Tethered Cord Syndrome	11.1%
268	Central Nervous System Neoplasms	11.1%
269	Complex partial seizures	11.1%
270	Iniencephaly	11.1%
271	Craniorachischisis	11.1%
272	Exencephaly	11.1%
273	Monoparesis	11.1%
274	Septo-Optic Dysplasia	11.1%
275	Cortical Dysplasia	11.1%
276	Neurogenic Inflammation	11.1%
277	Gait Disorders, Neurologic	11.1%
278	Neuromuscular Manifestations	11.1%
279	Malformations of Cortical Development	11.1%
280	Sweating, Gustatory	11%
281	Auriculotemporal Syndrome	11%
282	Galactosemias	11%
283	Urea Cycle Disorders, Inborn	11%
284	Tyrosinemias	11%
285	Alice in Wonderland Syndrome	11%
286	Meningitis, Cryptococcal	11%
287	Meningitis, Listeria	10.9%
288	Meningitis, Haemophilus	10.9%
289	Meningitis, Pneumococcal	10.9%
290	Demyelinating Diseases	10.8%
291	Demyelination	10.8%
292	Hyperprolactinemia	10.8%
293	Tarsal Tunnel Syndrome	10.7%
294	Cauda Equina Syndrome	10.7%
295	Auditory Perceptual Disorders	10.7%
296	Subclavian Steal Syndrome	10.6%
297	Pick Disease of the Brain	10.6%
298	Acrodynia	10.6%
299	Tardive Dyskinesia	10.5%
300	Central Nervous System Bacterial Infections	10.3%
301	Charcot-Marie-Tooth Disease	10.3%
302	Myasthenia Gravis, Autoimmune, Experimental	10.3%
303	Neuritis	10.1%
304	Ophthalmoplegia	10.1%
305	Polyneuritis	10.1%
306	Radiculitis	10.1%
307	Polyneuropathy	10.1%
308	External Ophthalmoplegia	10.1%
309	Mononeuritis	10.1%
310	Mononeuropathies	10.1%
311	Brachial Plexus Neuropathies	10.1%
312	Radiculopathy	10.1%
313	Mononeuropathy Multiplex	10.1%
314	Nerve Root Compression	10.1%
315	Carotid Stenosis	9.9%
316	Intracranial Aneurysm	9.9%
317	Intracranial Arteriosclerosis	9.8%
318	Cerebral Atherosclerosis	9.8%
319	Homocystinuria	9.8%
320	Subarachnoid Hemorrhage	9.8%
321	Cerebral Arteriosclerosis	9.8%
322	Cerebral Hemorrhage	9.8%
323	Cerebral Thrombosis	9.8%
324	Intracranial Embolism	9.8%
325	Intracranial Thrombosis	9.8%
326	Leigh Disease	9.8%
327	Coma, Post-Head Injury	9.6%
328	Jet Lag Syndrome	9.6%
329	Pupil Disorders	9.2%
330	Neurobehavioral Manifestations	9.2%
331	Brain Diseases	9.2%
332	Spinal Cord Ischemia	9.2%
333	West Nile Fever	9.1%
334	Tuberculosis, Central Nervous System	9%
335	Paraneoplastic Encephalomyelitis	9%
336	Tuberous Sclerosis	9%
337	Menkes Kinky Hair Syndrome	8.9%
338	AIDS Dementia Complex	8.9%
339	Myotonia Congenita	8.9%
340	Uveomeningoencephalitic Syndrome	8.8%
341	Cerebrospinal Fluid Otorrhea	8.8%
342	Cerebrospinal Fluid Rhinorrhea	8.8%
343	Neuritis, Autoimmune, Experimental	8.8%
344	Sturge-Weber Syndrome	8.8%
345	Vertigo	8.8%
346	Alcohol-Induced Disorders, Nervous System	8.8%
347	Gait Ataxia	8.8%
348	Giant Cell Arteritis	8.7%
349	Temporal Arteritis	8.7%
350	Vocal Cord Paralysis	8.7%
351	Acromegaly	8.6%
352	Carpal Tunnel Syndrome	8.6%
353	neurofibroma	8.5%
354	Sciatica	8.5%
355	Cerebral Amyloid Angiopathy	8.5%
356	Marchiafava-Bignami Disease	8.5%
357	Sinus Thrombosis, Intracranial	8.4%
358	Carbamoyl-Phosphate Synthase I Deficiency Disease	8.3%
359	Fabry Disease	8.2%
360	Carotid Artery Thrombosis	8.2%
361	Hematoma, Subdural	8.1%
362	Hematoma, Epidural, Cranial	8.1%
363	Myotonic Dystrophy	8.1%
364	Cubital Tunnel Syndrome	7.8%
365	Sciatic Neuropathy	7.8%
366	Ulnar Neuropathies	7.8%
367	Lesion of Sciatic Nerve	7.8%
368	Ulnar Neuritis	7.8%
369	Radial nerve compression	7.8%
370	Radial Tunnel Syndrome	7.8%
371	Peroneal Neuropathies	7.8%
372	Radial Neuropathy	7.8%
373	Median Neuropathy	7.8%
374	Sciatic Nerve Palsy	7.8%
375	Femoral Neuropathy	7.8%
376	Tibial Neuropathy	7.8%
377	Ulnar Nerve Palsy	7.8%
378	Postural Orthostatic Tachycardia Syndrome	7.8%
379	Radial nerve palsy	7.8%
380	Cavernous Sinus Thrombosis	7.8%
381	Sagittal Sinus Thrombosis	7.8%
382	Myositis	7.7%
383	Optic Atrophy	7.7%
384	Optic Neuritis	7.7%
385	Papilledema	7.7%
386	Strabismus	7.7%
387	Tolosa-Hunt Syndrome	7.7%
388	Isaacs syndrome	7.7%
389	Arsenic Poisoning	7.7%
390	Myotonic Disorders	7.7%
391	Myasthenic Syndromes, Congenital	7.7%
392	Diabetic Neuropathies	7.6%
393	Facial Injuries	7.6%
394	Facial Neuralgia	7.6%
395	Diabetic Amyotrophy	7.6%
396	Diabetic Autonomic Neuropathy	7.6%
397	Sleep Talking	7.6%
398	Manganese Poisoning	7.6%
399	Sleep Disorders, Intrinsic	7.6%
400	Orthostatic intolerance	7.6%
401	Akathisia	7.5%
402	Restlessness	7.5%
403	Psychomotor Agitation	7.5%
404	Voice Disorders	7.5%
405	Voice Disturbance	7.5%
406	Anosmia	7.5%
407	Ataxia	7.5%
408	Athetosis	7.5%
409	Catalepsy	7.5%
410	Dystonia	7.5%
411	Hemiplegia	7.5%
412	Locked-In Syndrome	7.5%
413	Meningeal Neoplasms	7.5%
414	Meningomyelocele	7.5%
415	Muscle Hypertonia	7.5%
416	Muscle hypotonia	7.5%
417	Myoclonus	7.5%
418	Myotonia	7.5%
419	Neuralgia	7.5%
420	Paraplegia	7.5%
421	Pseudobulbar Palsy	7.5%
422	Quadriplegia	7.5%
423	Spasm	7.5%
424	Spastic Paraplegia	7.5%
425	Status Epilepticus	7.5%
426	Taste Disorders	7.5%
427	Tremor	7.5%
428	Spina Bifida	7.5%
429	Monoplegia	7.5%
430	Hypokinesia	7.5%
431	Paraparesis	7.5%
432	Bradykinesia	7.5%
433	Waxy flexibility	7.5%
434	Action Tremor	7.5%
435	Resting Tremor	7.5%
436	Dysosmia	7.5%
437	Quadriparesis	7.5%
438	Mercury Poisoning, Nervous System	7.5%
439	Olfaction Disorders	7.5%
440	Myokymia	7.5%
441	Lead Poisoning, Nervous System	7.5%
442	Vestibular Neuronitis	7.5%
443	Somatosensory Disorders	7.5%
444	Neuropathic pain	7.5%
445	Hyperkinesia	7.5%
446	Intention tremor	7.5%
447	Alcohol Withdrawal Seizures	7.4%
448	Zellweger Syndrome	7.4%
449	Anterior Spinal Artery Syndrome	7.4%
450	Glycogen storage disease type II	7.4%
451	Smith-Magenis syndrome	7.3%
452	Neuroaspergillosis	7.3%
453	Dural Arteriovenous Fistula	7.3%
454	Optic Nerve Glioma	7.3%
455	Hematoma, Subdural, Intracranial	7.2%
456	Hematoma, Subdural, Chronic	7.2%
457	Hematoma, Subdural, Acute	7.2%
458	Gait Apraxia	7%
459	Polyradiculopathy	6.6%
460	Alstrom Syndrome	6.6%
461	Nelson Syndrome	6.5%
462	Pseudorabies	6.4%
463	Hand-Arm Vibration Syndrome	6.4%
464	Vision Disorders	6.2%
465	Metamorphopsia	6.2%
466	Visual Impairment	6.2%
467	Fibromyalgia	6.2%
468	Optic Neuropathy, Ischemic	6.2%
469	Anterior Ischemic Optic Neuropathy	6.2%
470	Medial Tibial Stress Syndrome	6.2%
471	Reflex, Abnormal	6.2%
472	Hyporeflexia	6.2%
473	Hyperreflexia	6.2%
474	Facial Hemiatrophy	6.1%
475	Melkersson-Rosenthal Syndrome	6.1%
476	Mitochondrial Myopathies	6.1%
477	Prolactinoma	6.1%
478	Growth Hormone-Secreting Pituitary Adenoma	6.1%
479	Gaucher Disease	6.1%
480	Anisocoria	6.1%
481	Confusion	6.1%
482	Facial paralysis	6.1%
483	Lethargy	6.1%
484	Memory Disorders	6.1%
485	Muscle Cramp	6.1%
486	Perceptual Disorders	6.1%
487	Psychomotor Disorders	6.1%
488	Tonic Pupil	6.1%
489	Eosinophilia-Myalgia Syndrome	6.1%
490	Anhedonia	6.1%
491	Disorientation	6.1%
492	Facial Paresis	6.1%
493	Memory Loss	6.1%
494	Hemisensory Neglect	6.1%
495	Dysacusis	6.1%
496	Sleep Bruxism	6%
497	Classical Lissencephalies and Subcortical Band Heterotopias	6%
498	Toxoplasmosis, Congenital	6%
499	Neurosyphilis	6%
500	Anencephaly	6%
501	Meningocele	6%
502	Muscular Atrophy	6%
503	Respiratory Paralysis	6%
504	Encephalocele	6%
505	Malaria, Cerebral	6%
506	Tetany	6%
507	Thoracic Outlet Syndrome	5.9%
508	Neurocysticercosis	5.9%
509	Esotropia	5.8%
510	Exotropia	5.8%
511	Hypotension, Orthostatic	5.8%
512	Sleep Apnea Syndromes	5.8%
513	Polymyositis	5.8%
514	Post-Exercise Hypotension	5.8%
515	Amyloid Neuropathies, Familial	5.8%
516	Disorders of Excessive Somnolence	5.8%
517	Sleep Initiation and Maintenance Disorders	5.8%
518	Night Terrors	5.8%
519	Somnambulism	5.8%
520	Trigeminal Nerve Disorder	5.8%
521	Transient Insomnia	5.8%
522	Sleep Paralysis	5.8%
523	Chronic Insomnia	5.8%
524	REM Sleep Behavior Disorder	5.8%
525	Hypersomnia	5.8%
526	Dermal Sinus	5.8%
527	Dysgeusia	5.8%
528	Formication	5.8%
529	Hyperalgesia	5.8%
530	Hyperesthesia	5.8%
531	Hypesthesia	5.8%
532	Language Disorders	5.8%
533	Numbness	5.8%
534	Paresthesia	5.8%
535	Paraparesis, Spastic	5.8%
536	Spina Bifida Cystica	5.8%
537	Trismus	5.8%
538	Spina Bifida Occulta	5.8%
539	Epilepsia Partialis Continua	5.8%
540	Hypogeusia	5.8%
541	Meningeal Carcinomatosis	5.8%
542	Brown-Sequard Syndrome	5.8%
543	Lissencephaly	5.8%
544	Polymicrogyria	5.8%
545	Pachygyria	5.8%
546	Schizencephaly	5.8%
547	Lockjaw	5.8%
548	Allodynia	5.8%
549	Lead Poisoning, Nervous System, Childhood	5.8%
550	Lead Poisoning, Nervous System, Adult	5.8%
551	Periventricular Nodular Heterotopia	5.8%
552	Ageusia	5.8%
553	Tay-Sachs Disease	5.6%
554	Alexia	5.6%
555	Dyslexia	5.6%
556	Acoustic Neuroma	5.4%
557	Niemann-Pick Disease, Type C	5.3%
558	Neurofibrosarcoma	5.3%
559	Duane Retraction Syndrome	5.1%
560	Brain Diseases, Metabolic	5.1%
561	Lyme Neuroborreliosis	5.1%
562	Consciousness Disorders	5.1%
563	Mental Retardation	5.1%
564	Muscle Weakness	5.1%
565	Depressed Level of Consciousness	5.1%
566	Mental deficiency	5.1%
567	Intellectual Disability	5.1%
568	Mobius Syndrome	5.1%
569	Bell Palsy	5.1%
570	Catatonia	5.1%
571	Herpes Zoster Oticus	5%
572	Familial Periodic Paralysis	5%
573	Waterhouse-Friderichsen Syndrome	5%
574	Aphonia	5%
575	Sleep Deprivation	5%
576	Dysphonia	5%
577	Sleep Apnea, Obstructive	4.9%
578	Sleep Apnea, Central	4.9%
579	Narcolepsy	4.9%
580	Trigeminal Neuralgia	4.9%
581	Kleine-Levin Syndrome	4.9%
582	Agraphia	4.9%
583	Anomia	4.9%
584	Cluttering	4.9%
585	Language Development Disorders	4.9%
586	Speech Disorders	4.9%
587	Syncope	4.9%
588	Stupor	4.9%
589	Dysgraphia	4.9%
590	Presyncope	4.9%
591	Dyslalia	4.9%
592	Kearns-Sayre syndrome	4.9%
593	Eye Injuries	4.8%
594	Optic Atrophy, Hereditary, Leber	4.7%
595	Muscular Dystrophy	4.7%
596	Congenital nystagmus	4.7%
597	Orbital Myositis	4.7%
598	Diplopia	4.7%
599	Muscle Rigidity	4.7%
600	Muscle Spasticity	4.7%
601	Scotoma	4.7%
602	Photophobia	4.7%
603	Cogwheel Rigidity	4.7%
604	Hemifacial Spasm	4.7%
605	Amaurosis	4.7%
606	Blindness	4.7%
607	Nuchal Rigidity	4.7%
608	Pyomyositis	4.7%
609	Agnosia	4.6%
610	Apraxias	4.6%
611	Hallucinations	4.6%
612	Hemianopsia	4.6%
613	Hyperacusis	4.6%
614	Tinnitus	4.6%
615	Visual Agnosia	4.6%
616	Anosognosia	4.6%
617	Wernicke-Korsakoff Syndrome	4.6%
618	Phonophobia	4.6%
619	Hearing Loss	4.6%
620	Sarcopenia	4.6%
621	Cataplexy	4.5%
622	Aphasia	4.5%
623	Articulation Disorders	4.5%
624	Echolalia	4.5%
625	Stuttering	4.5%
626	Dysphasia	4.5%
627	Myalgia	4.3%
628	Dysarthria	4.3%
629	Neuronal Ceroid-Lipofuscinoses	4.2%
630	Eye Burns	4%
631	Welander Distal Myopathy	4%
632	Amaurosis Fugax	3.9%
633	Blindness, Cortical	3.9%
634	Dyscalculia	3.9%
635	Rett Syndrome	3.9%
636	Deafness	3.9%
637	Hearing Loss, Sudden	3.9%
638	Gerstmann Syndrome	3.9%
639	Hearing Loss, Bilateral	3.9%
640	Hearing Loss, High-Frequency	3.9%
641	Hearing Loss, Mixed Conductive-Sensorineural	3.9%
642	Prosopagnosia	3.9%
643	Apraxia, Ideomotor	3.9%
644	Charles Bonnet Syndrome	3.9%
645	Hearing Loss, Unilateral	3.9%
646	Complete Hearing Loss	3.9%
647	Alien Hand Syndrome	3.9%
648	Deaf Mutism	3.9%
649	Amnesia	3.9%
650	Delirium	3.9%
651	Dissociative Amnesia	3.9%
652	Color blindness	3.9%
653	Global Amnesia	3.9%
654	Cri-du-Chat Syndrome	3.9%
655	Down Syndrome	3.9%
656	Trisomy 21	3.9%
657	POEMS Syndrome	3.9%
658	Meningioma	3.9%
659	Williams Syndrome	3.9%
660	Microcephaly	3.8%
661	Macrocephaly	3.8%
662	Hypokalemic periodic paralysis	3.8%
663	Aicardi's syndrome	3.8%
664	Porencephaly	3.8%
665	Hoarseness	3.8%
666	Cockayne Syndrome	3.7%
667	Alcohol Withdrawal Delirium	3.7%
668	Mutism	3.7%
669	Selective Mutism	3.7%
670	Alexia, Pure	3.4%
671	Dermatomyositis	3.4%
672	Corneal Scar	3.4%
673	Holoprosencephaly	3.3%
674	Prader-Willi Syndrome	3.3%
675	Muscular Dystrophy, Duchenne	3.3%
676	Retrograde amnesia	3.3%
677	Amnesia, Anterograde	3.3%
678	Phantom pain	3.3%
679	Phantom Limb Pain	3.3%
680	Corneal Perforation	3%
681	Fragile X Syndrome	2.8%
682	Rubinstein-Taybi Syndrome	2.6%
683	Mucopolysaccharidosis II	1.9%

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120140