MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Head and Neck Neoplasms

(UMLS:C0018671)

Definition:: Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)
UMLS ID:: C0018671
MeSH ID:: D006258

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.588.443

Synonym(s)

Head and Neck Neoplasms

Head and Neck Neoplasm

Head and Neck Neoplasm (Excluding Central Nervous System)

Head and Neck Tumor

Head and neck tumor

Neoplasm of Head and Neck

Neoplasm of head AND/OR neck

Neoplasm of head and neck

Neoplasm of the Head and Neck

10.

Tumor of Head and Neck

11.

Tumor of head and neck

12.

Tumor of the Head and Neck

13.

Tumour of head and neck

14.

head and neck neoplasms

15.

head neck neoplasms

16.

head neck tumor

17.

head neck tumors

18.

head neck tumours

19.

head/neck neoplasm

Associated Drug(s)

	Name	Reference(s)	Data Source
1	5-FU-CDDP protocol	9617462 10895216	CTD
2	Amifostine	15064010	CTD
3	Bleomycin	6173125	CTD
4	Bortezomib	15509775	CTD
5	Calcitriol	16886663	CTD
6	Capecitabine	20722491	CTD
7	Carboplatin	View details 8901858 9149030 9740546 9774881 19396017	CTD
8	Decitabine	19215824	CTD
9	Doxorubicin	4795227 7379058 15692506	CTD
10	Epirubicin	6584236	CTD
11	Fluorouracil	15102660 15162350 18337622	CTD
12	Gefitinib	21768327	CTD
13	Hydroxyurea	5775014	CTD
14	IDN 5109	16391850	CTD
15	Indomethacin	15482327	CTD
16	Leucovorin	8569964	CTD
17	Methotrexate	8569964	CTD
18	Misonidazole	2689395	CTD
19	Mitomycin	8901858 9774881	CTD
20	Nicotine	11592233	CTD
21	Paclitaxel	View details 7692001 8643971 9149030 19396017	CTD
22	Phenytoin	1186408	CTD
23	Resveratrol	23921149	CTD
24	Sirolimus	19435901	CTD
25	Tretinoin	16096774	CTD
26	Vinblastine	6173125	CTD
27	Vindesine	7438126	CTD
28	Vinorelbine	8901858 9774881	CTD
29	alvocidib	9802881	CTD
30	aranoza	11826486	CTD
31	edatrexate	9740546	CTD
32	nimesulide	15482327	CTD
33	retinol palmitate	15984520	CTD
34	tesmilifene	18986763	CTD
35	turmeric extract	18462866 18829502	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Abdominal Neoplasms	42.9%
2	Soft Tissue Neoplasms	42.9%
3	Thoracic Neoplasms	42.9%
4	Retroperitoneal Neoplasms	31%
5	Digestive System Neoplasms	30%
6	Endocrine Gland Neoplasms	30%
7	Eye Neoplasms	30%
8	Nervous System Neoplasms	30%
9	Bone neoplasms	28.6%
10	Skin Neoplasms	28.6%
11	Hematologic Neoplasms	28.6%
12	Splenic Neoplasms	27.9%
13	Acanthoma	25.8%
14	Peritoneal Neoplasms	25%
15	Hamartoma	23.1%
16	Neoplasms, Hormone-Dependent	23.1%
17	Neoplasms, Multiple Primary	23.1%
18	Paraneoplastic Syndromes	23.1%
19	Precancerous Conditions	23.1%
20	Neoplasms, Second Primary	23.1%
21	Paraneoplastic Encephalomyelitis	22.8%
22	Mammary Neoplasms, Experimental	22.2%
23	Pancreatic Neoplasm	20.9%
24	Central Nervous System Neoplasms	20.9%
25	Vascular Neoplasms	20.9%
26	Thymus Neoplasms	20.9%
27	Genital Neoplasms, Female	20.5%
28	Breast Neoplasms, Male	20.2%
29	Triple Negative Breast Neoplasms	20.2%
30	Multiple Endocrine Neoplasia	19.8%
31	Carcinoma, Lobular	18.2%
32	Thymoma	17.6%
33	Meningioma	16.9%
34	Meningeal Neoplasms	16.9%
35	Testicular Neoplasms	15.9%
36	Carcinoma, Pancreatic Ductal	15.9%
37	Adrenal Gland Neoplasms	15.8%
38	Gastrointestinal Neoplasms	15.8%
39	Genital Neoplasms, Male	15.8%
40	Liver neoplasms	15.8%
41	Uveal Neoplasms	15.8%
42	Urologic Neoplasms	15.5%
43	Sebaceous Gland Neoplasms	15.3%
44	Spinal Neoplasms	15.3%
45	Bone Marrow Neoplasms	15.3%
46	Cyst	15%
47	Multiple Endocrine Neoplasia Type 1	15%
48	Neoplastic Processes	15%
49	Neoplastic Syndromes, Hereditary	15%
50	Pregnancy Complications, Neoplastic	15%
51	Carcinoma, Ehrlich Tumor	14.9%
52	Dermoid Cyst	14.9%
53	Carcinoma, Lewis Lung	14.9%
54	Meningeal Carcinomatosis	14.9%
55	Carcinoma 256, Walker	14.8%
56	Neoplasms, Experimental	14.6%
57	insulinoma	14.6%
58	Gastrinoma	14.5%
59	Glucagonoma	14.5%
60	Vipoma	14.3%
61	Erythroplasia	14.3%
62	Follicular cyst	14.3%
63	leukemia	14.3%
64	Mucocele	14.3%
65	Neoplasms, Germ Cell and Embryonal	14.3%
66	Neoplasms, Glandular and Epithelial	14.3%
67	Pilonidal Cyst	14.3%
68	Thyroglossal Cyst	14.3%
69	Synovial Cyst	14.3%
70	Germ Cell Cancer	14.3%
71	Aberrant Crypt Foci	14.3%
72	Paraneoplastic Cerebellar Degeneration	14%
73	Neuroectodermal Tumors	13.6%
74	Acoustic Neuroma	13.5%
75	Hepatocellular Adenoma	13.3%
76	Neoplasms, Neuroepithelial	13.3%
77	Gliomatosis cerebri	13.3%
78	Lung Neoplasms	13%
79	Pleural Neoplasms	13%
80	Liver Neoplasms, Experimental	12.9%
81	Brain Neoplasms	12.6%
82	Spinal Cord Neoplasms	12.6%
83	Parathyroid Neoplasms	12.5%
84	Thyroid Neoplasm	12.5%
85	Thyroid carcinoma	12.5%
86	melanoma	12.4%
87	Uterine Neoplasms	12.4%
88	Vaginal Neoplasms	12.4%
89	Vulvar Neoplasms	12.4%
90	Uterine Cancer	12.4%
91	Leydig Cell Tumor	12.4%
92	Carcinosarcoma	12.4%
93	Hemangiosarcoma	12.4%
94	Leukemia L1210	12.4%
95	Leukemia P388	12.4%
96	lymphangiosarcoma	12.4%
97	Fallopian Tube Neoplasms	12.3%
98	Trophoblastic Neoplasms	12.1%
99	Retinoblastoma	12%
100	Leukemia, Experimental	12%
101	Medulloblastoma	11.9%
102	Melanoma, Experimental	11.8%
103	Sarcoma 180	11.7%
104	Limbic Encephalitis	11.6%
105	Optic Nerve Glioma	11.5%
106	Bronchial Neoplasms	11.5%
107	Adenoma, Acidophil	11.5%
108	Ganglioneuroma	11.5%
109	Glioma	11.5%
110	Malignant Glioma	11.5%
111	Multiple Pulmonary Nodules	11.3%
112	Pituitary Adenoma	11.2%
113	Pituitary Neoplasms	11.2%
114	Basal cell carcinoma	11.1%
115	Carcinoma, Papillary	11.1%
116	Squamous cell carcinoma	11.1%
117	Chondrosarcoma	11.1%
118	Craniopharyngioma	11.1%
119	Cystadenoma	11.1%
120	leiomyosarcoma	11.1%
121	liposarcoma	11.1%
122	Mesothelioma	11.1%
123	Supratentorial Neoplasms	11.1%
124	synovial sarcoma	11.1%
125	Neuroectodermal Tumor, Melanotic	11.1%
126	Angiomyolipoma	11.1%
127	Clear Cell Sarcoma of Soft Tissue	11.1%
128	Alveolar Soft Part Sarcoma	11.1%
129	Neuroendocrine Tumors	11.1%
130	Sarcoma, Myeloid	11.1%
131	Carcinoma, Basal Cell	11.1%
132	Carcinoid Tumor	11%
133	Endometrial Neoplasms	11%
134	Neurilemmoma	11%
135	Hutchinson's Melanotic Freckle	11%
136	Melanoma, Amelanotic	11%
137	Sarcoma, Experimental	11%
138	Prolactinoma	11%
139	Growth Hormone-Secreting Pituitary Adenoma	11%
140	Neoplasms, Radiation-Induced	10.8%
141	Astrocytoma	10.6%
142	Ependymoma	10.6%
143	oligodendroglioma	10.6%
144	Ganglioglioma	10.6%
145	gliosarcoma	10.6%
146	Anaplastic astrocytoma	10.6%
147	Anaplastic Oligodendroglioma	10.6%
148	Cystadenocarcinoma	10.5%
149	Fibrosarcoma	10.5%
150	Osteosarcoma	10.5%
151	Mucoepidermoid Carcinoma	10.5%
152	Brain Stem Neoplasms	10.4%
153	Adenoma	10.3%
154	Ameloblastoma	10.3%
155	Angiokeratoma	10.3%
156	Carcinoma	10.3%
157	Chordoma	10.3%
158	Hemangioma	10.3%
159	hemangiopericytoma	10.3%
160	Lymphangioma	10.3%
161	Malignant Carcinoid Syndrome	10.3%
162	Mesenchymoma	10.3%
163	Nevus	10.3%
164	Teratoma	10.3%
165	Tracheal Neoplasms	10.3%
166	Hepatoblastoma	10.3%
167	Mixed Tumor, Mullerian	10.3%
168	Germinoma	10.3%
169	Teratocarcinoma	10.3%
170	Angiofibroma	10.3%
171	Sarcoma	10.3%
172	Epithelioma	10.3%
173	Choriocarcinoma	10.2%
174	Central Nervous System Cysts	10.2%
175	Adenofibroma	10.2%
176	Fibroadenoma	10.2%
177	Malignant Fibrous Histiocytoma	10.2%
178	Lambert-Eaton Myasthenic Syndrome	10.1%
179	Glioblastoma	10.1%
180	Neuroblastoma	10.1%
181	Glioblastoma Multiforme	10.1%
182	Nephroblastoma	10.1%
183	ovarian neoplasm	10.1%
184	Bile Duct Neoplasms	10.1%
185	gallbladder neoplasm	10.1%
186	Intestinal Neoplasms	10.1%
187	Penile Neoplasms	10.1%
188	Prostatic Neoplasms	10.1%
189	Stomach Neoplasms	10.1%
190	Choroid Plexus Papilloma	10%
191	Thyroid Nodule	10%
192	Ganglioneuroblastoma	9.9%
193	Bowen's Disease	9.9%
194	Paraganglioma	9.9%
195	Rhabdomyosarcoma	9.9%
196	Giant Cell Tumor of Bone	9.9%
197	Polycythemia Vera	9.9%
198	Adrenocortical carcinoma	9.8%
199	Leukemia, Radiation-Induced	9.7%
200	Dermatofibrosarcoma	9.6%
201	Dermatofibrosarcoma Protuberans	9.6%
202	Leukoplakia	9.5%
203	Lymphocele	9.5%
204	Pancreatic Cyst	9.5%
205	granulosa cell tumor	9.3%
206	Carcinoma, Ovarian Epithelial	9.3%
207	Barrett Esophagus	9.3%
208	Breast Cyst	9.3%
209	Histiocytic Disorders, Malignant	9.3%
210	Actinic keratosis	9.3%
211	Mediastinal Cyst	9.3%
212	Neoplasm Invasiveness	9.3%
213	Neoplasm Metastasis	9.3%
214	Neoplasm Recurrence, Local	9.3%
215	Parovarian Cyst	9.3%
216	Pericardial Cyst	9.3%
217	Thymic Cyst	9.3%
218	Carcinogenesis	9.3%
219	Myxoid cyst	9.3%
220	Metastasis	9.3%
221	Pheochromocytoma	9.3%
222	Alveolar rhabdomyosarcoma	9.3%
223	Leukemia, Plasma Cell	9.2%
224	Mesoblastic Nephroma	9.1%
225	Pleural Effusion, Malignant	9%
226	Prostatic Neoplasms, Castration-Resistant	8.9%
227	Opsoclonus-Myoclonus Syndrome	8.8%
228	Nelson Syndrome	8.8%
229	Adenocarcinoma	8.5%
230	Carcinoma in Situ	8.5%
231	Carcinoma, Transitional Cell	8.5%
232	Phyllodes Tumor	8.5%
233	Dysgerminoma	8.5%
234	Hemangioendothelioma	8.5%
235	Lipoma	8.5%
236	Myoma	8.5%
237	Myxoma	8.5%
238	Neuroma	8.5%
239	Papilloma	8.5%
240	Pseudomyxoma Peritonei	8.5%
241	Seminoma	8.5%
242	Papillomatosis	8.5%
243	Angiolipoma	8.5%
244	Myelolipoma	8.5%
245	Neoplasms, Bone Tissue	8.5%
246	Neoplasms, Fibrous Tissue	8.5%
247	Smooth Muscle Tumor	8.5%
248	Adenomatosis, Pulmonary	8.5%
249	Adenomatous Polyps	8.5%
250	Carcinoma, Large Cell	8.5%
251	Carcinoma, Small Cell	8.5%
252	Desmoplastic Small Round Cell Tumor	8.5%
253	Chondroma	8.5%
254	Enchondroma	8.5%
255	Esophageal Neoplasms	8.4%
256	Renal Cell Carcinoma	8.3%
257	Papillary Renal Cell Carcinoma	8.3%
258	Cerebellar Neoplasms	8.3%
259	Bladder Neoplasm	8.3%
260	Kidney Neoplasm	8.3%
261	Ureteral Neoplasms	8.3%
262	Urethral Neoplasms	8.3%
263	Lymphomatoid Granulomatosis	8.3%
264	Adenomatous Polyposis Coli	8.2%
265	Tuberous Sclerosis	8.2%
266	Carcinoid Heart Disease	8.2%
267	Composite Lymphoma	8%
268	Carcinoma, Endometrioid	7.9%
269	Hydatidiform Mole	7.8%
270	Myelitis, Transverse	7.7%
271	Adenoid Cystic Carcinoma	7.6%
272	fibroma	7.6%
273	Fibromatosis	7.6%
274	Osteoblastoma	7.6%
275	Osteoma	7.6%
276	Rhabdomyoma	7.6%
277	Chondromatosis	7.6%
278	Adenocarcinoma, Clear Cell	7.6%
279	Cholangiocarcinoma	7.6%
280	Cervical Intraepithelial Neoplasia	7.6%
281	Hemangioblastoma	7.6%
282	Lymphoma, Extranodal NK-T-Cell	7.6%
283	Cecal Neoplasms	7.4%
284	Duodenal Neoplasms	7.4%
285	Neurofibrosarcoma	7.1%
286	Fibromatosis, Aggressive	7.1%
287	Fibromatosis, Abdominal	7.1%
288	Klatskin Tumor	7.1%
289	Basal Cell Nevus Syndrome	7.1%
290	Lymphoma	6.9%
291	Appendiceal Neoplasms	6.9%
292	Colonic Neoplasms	6.9%
293	Rectal Neoplasms	6.9%
294	Endometrial Stromal Sarcoma	6.9%
295	Pancreatic Pseudocyst	6.8%
296	Plasmacytoma	6.8%
297	Corpus Luteum Cyst	6.8%
298	Ovarian Cysts	6.8%
299	Malignant histiocytosis	6.7%
300	Lymphatic Metastasis	6.7%
301	Neoplasms, Unknown Primary	6.7%
302	Leukemic Infiltration	6.7%
303	Histiocytic sarcoma	6.7%
304	Neoplasm Micrometastasis	6.7%
305	Lymphangioleiomyomatosis	6.6%
306	Nose Neoplasms	6.4%
307	Palatal Neoplasms	6.4%
308	Colorectal Neoplasms	6.3%
309	Denys-Drash Syndrome	5.9%
310	Anus Neoplasms	5.7%
311	Sigmoid Neoplasms	5.7%
312	Choledochal Cyst	5.6%
313	Leukemia, Myelomonocytic, Chronic	5.6%
314	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	5.6%
315	Peutz-Jeghers Syndrome	5.4%
316	Mastocytoma	5%
317	Hodgkin Disease	5%
318	Lymphoma, Non-Hodgkin	5%
319	Mastocytosis, Systemic	5%
320	Polycystic Ovary Syndrome	5%
321	Leukemia, Myeloid, Chronic-Phase	4.9%
322	Mastocytosis	4.3%
323	Sturge-Weber Syndrome	4.3%
324	Cell Transformation, Viral	4.2%
325	Gastrointestinal Stromal Tumors	4.2%
326	Hemangioma, Cavernous	4.2%
327	Leukemia, T-Cell	4.1%
328	Leukemia, B-Cell	4.1%
329	neurofibroma	4.1%
330	Lymphoma, Follicular	4.1%
331	T-Cell Lymphoma	4.1%
332	Mantle cell lymphoma	4.1%
333	Leukoplakia, Oral	4%
334	Primary amyloidosis	4%
335	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	3.7%
336	Leukemia, Large Granular Lymphocytic	3.7%
337	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	3.7%
338	Lymphoma, T-Cell, Cutaneous	3.7%
339	Lymphoma, AIDS-Related	3.7%
340	Enteropathy-Associated T-Cell Lymphoma	3.7%
341	Primary Effusion Lymphoma	3.7%
342	Dupuytren Contracture	3.6%
343	Urticaria Pigmentosa	3.5%
344	Mycosis Fungoides	3.4%
345	Lymphomatoid Papulosis	3.4%
346	Plasmablastic lymphoma	3.4%
347	Xeroderma Pigmentosum	3%
348	Waldenstrom Macroglobulinemia	2.9%
349	Multiple Myeloma	2.9%
350	Zollinger-Ellison syndrome	2.5%
351	Burkitt Lymphoma	2.4%
352	Sezary Syndrome	2.3%
353	Radicular Cyst	2.3%
354	Nasopharyngeal carcinoma	2%

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