MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Fibroadenoma

(UMLS:C0206650)

Definition:: An adenoma containing fibrous tissue. It should be differentiated from ADENOFIBROMA which is a tumor composed of connective tissue (fibroma) containing glandular (adeno-) structures. (From Dorland, 27th ed)
UMLS ID:: C0206650
MeSH ID:: D018226

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.450.565.590.595.350|C04.557.470.625.350

Synonym(s)

Fibroadenoma

Fibroadenoma NOS

Fibroadenoma, NOS

Fibroadenoma, no ICD-O subtype

Fibroadenoma, no International Classification of Diseases for Oncology subtype

fibroadenoma

fibroadenoma; unspecified site

fibroadenomas

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Isotretinoin	FAERS: 8		US FAERS
2	2-nitrotoluene		12087420 12504353	CTD
3	3-amino-1-methyl-5H-pyrido(4,3-b)indole		8407549	CTD
4	4-vinyl-1-cyclohexene dioxide		21621605	CTD
5	Atrazine		21768606	CTD
6	Benzoyl Peroxide			OFFSIDES
7	Daunorubicin		639071 1268859	CTD
8	Doxorubicin		639071 1268859 3608097	CTD
9	Erythromycin			OFFSIDES
10	Estrogens, Conjugated (USP)			OFFSIDES
11	Medroxyprogesterone			OFFSIDES
12	Minocycline			OFFSIDES
13	Tretinoin			OFFSIDES
14	Valproic Acid		1729766	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Adenofibroma	55%
2	Fibrosarcoma	33.9%
3	Chondrosarcoma	31.7%
4	synovial sarcoma	31.7%
5	Clear Cell Sarcoma of Soft Tissue	31.7%
6	leukemia	30.6%
7	Neoplasms, Germ Cell and Embryonal	30.6%
8	Germ Cell Cancer	30.6%
9	Neoplasms, Neuroepithelial	30.5%
10	Gliomatosis cerebri	30.5%
11	Adenoma	29.9%
12	Carcinoma	29.9%
13	Epithelioma	29.9%
14	fibroma	29.4%
15	Fibromatosis	29.4%
16	Basal cell carcinoma	28.5%
17	Carcinoma, Papillary	28.5%
18	Squamous cell carcinoma	28.5%
19	Cystadenoma	28.5%
20	Mesothelioma	28.5%
21	Carcinoma, Basal Cell	28.5%
22	Malignant Fibrous Histiocytoma	27.1%
23	Sarcoma	26.7%
24	Myxoma	26.4%
25	Neoplasms, Bone Tissue	26.4%
26	Chondroma	26.4%
27	Enchondroma	26.4%
28	Neuroectodermal Tumors	25.7%
29	Giant Cell Tumor of Bone	25%
30	Carcinosarcoma	24.6%
31	Hemangiosarcoma	24.6%
32	lymphangiosarcoma	24.6%
33	Cystadenocarcinoma	24.4%
34	Osteosarcoma	24.4%
35	Mucoepidermoid Carcinoma	24.4%
36	leiomyosarcoma	23.6%
37	liposarcoma	23.6%
38	Angiomyolipoma	23.6%
39	Alveolar Soft Part Sarcoma	23.6%
40	Dermatofibrosarcoma	23%
41	Dermatofibrosarcoma Protuberans	23%
42	Histiocytic Disorders, Malignant	23%
43	Carcinoma, Ehrlich Tumor	22.2%
44	Carcinoma, Lewis Lung	22.2%
45	Fibromatosis, Aggressive	20.4%
46	Fibromatosis, Abdominal	20.4%
47	Bowen's Disease	20.3%
48	Adenoma, Acidophil	19.9%
49	Ganglioneuroma	19.9%
50	Glioma	19.9%
51	Malignant Glioma	19.9%
52	Hamartoma	19.9%
53	Neoplasms, Hormone-Dependent	19.9%
54	Neoplasms, Multiple Primary	19.9%
55	Paraneoplastic Syndromes	19.9%
56	Precancerous Conditions	19.9%
57	Neoplasms, Second Primary	19.9%
58	Sarcoma, Myeloid	19.6%
59	Carcinoma, Lobular	19.2%
60	Adenocarcinoma	18.9%
61	Carcinoma in Situ	18.9%
62	Carcinoma, Transitional Cell	18.9%
63	Papilloma	18.9%
64	Pseudomyxoma Peritonei	18.9%
65	Papillomatosis	18.9%
66	Adenomatosis, Pulmonary	18.9%
67	Adenomatous Polyps	18.9%
68	Carcinoma, Large Cell	18.9%
69	Carcinoma, Small Cell	18.9%
70	melanoma	18.8%
71	Carcinoma 256, Walker	18.8%
72	Acanthoma	18.6%
73	Lymphoma	18.4%
74	Medulloblastoma	18.4%
75	Meningioma	18.2%
76	Composite Lymphoma	17.1%
77	Ameloblastoma	17%
78	Angiokeratoma	17%
79	Chordoma	17%
80	Hemangioma	17%
81	hemangiopericytoma	17%
82	Lymphangioma	17%
83	Mesenchymoma	17%
84	Nevus	17%
85	Teratoma	17%
86	Hepatoblastoma	17%
87	Mixed Tumor, Mullerian	17%
88	Germinoma	17%
89	Teratocarcinoma	17%
90	Angiofibroma	17%
91	Osteoblastoma	16.7%
92	Osteoma	16.7%
93	Chondromatosis	16.7%
94	Carcinoid Tumor	16.7%
95	Trophoblastic Neoplasms	16.6%
96	Leukemia, Plasma Cell	16.5%
97	Leukemia, Experimental	16.5%
98	Mastocytosis	16.3%
99	Neurofibrosarcoma	16.2%
100	Gastrointestinal Stromal Tumors	16.1%
101	Phyllodes Tumor	15.7%
102	Lipoma	15.7%
103	Myoma	15.7%
104	Angiolipoma	15.7%
105	Myelolipoma	15.7%
106	Smooth Muscle Tumor	15.7%
107	Desmoplastic Small Round Cell Tumor	15.7%
108	Sarcoma, Experimental	15.7%
109	Craniopharyngioma	15.6%
110	Neuroectodermal Tumor, Melanotic	15.6%
111	Neuroendocrine Tumors	15.6%
112	Dermoid Cyst	15.6%
113	Rhabdomyosarcoma	15.5%
114	Cyst	15%
115	Neoplastic Processes	15%
116	Neoplastic Syndromes, Hereditary	15%
117	Pregnancy Complications, Neoplastic	15%
118	Choriocarcinoma	14.9%
119	Neoplasms, Experimental	14.8%
120	Astrocytoma	14.7%
121	Ependymoma	14.7%
122	oligodendroglioma	14.7%
123	Ganglioglioma	14.7%
124	gliosarcoma	14.7%
125	Anaplastic astrocytoma	14.7%
126	Anaplastic Oligodendroglioma	14.7%
127	Neoplasms, Glandular and Epithelial	14%
128	Leukemia, Radiation-Induced	13.9%
129	Melanoma, Experimental	13.6%
130	Endometrial Stromal Sarcoma	13.6%
131	Adenoid Cystic Carcinoma	13.5%
132	Adenocarcinoma, Clear Cell	13.5%
133	Cholangiocarcinoma	13.5%
134	Cervical Intraepithelial Neoplasia	13.5%
135	Malignant Carcinoid Syndrome	13.1%
136	Lymphangioleiomyomatosis	13.1%
137	Neurilemmoma	12.9%
138	Hutchinson's Melanotic Freckle	12.9%
139	Melanoma, Amelanotic	12.9%
140	Plasmacytoma	12.8%
141	Malignant histiocytosis	12.7%
142	Histiocytic sarcoma	12.7%
143	Mastocytoma	12.7%
144	Dupuytren Contracture	12.6%
145	Mastocytosis, Systemic	12.6%
146	Retinoblastoma	12.5%
147	Thymoma	12.4%
148	Glioblastoma	12.2%
149	Neuroblastoma	12.2%
150	Glioblastoma Multiforme	12.2%
151	Leukemia L1210	12.1%
152	Leukemia P388	12.1%
153	Sarcoma 180	12.1%
154	Neoplasms, Radiation-Induced	11.8%
155	Multiple Endocrine Neoplasia	11.5%
156	Alveolar rhabdomyosarcoma	11.5%
157	Hepatocellular Adenoma	11.4%
158	Basal Cell Nevus Syndrome	11%
159	Ganglioneuroblastoma	10.9%
160	Klatskin Tumor	10.8%
161	Paraganglioma	10.7%
162	Carcinoma, Pancreatic Ductal	10.6%
163	Dysgerminoma	10.4%
164	Hemangioendothelioma	10.4%
165	Neuroma	10.4%
166	Seminoma	10.4%
167	Rhabdomyoma	10.3%
168	Abdominal Neoplasms	10.2%
169	Erythroplasia	10.2%
170	Follicular cyst	10.2%
171	Head and Neck Neoplasms	10.2%
172	Mucocele	10.2%
173	Pilonidal Cyst	10.2%
174	Soft Tissue Neoplasms	10.2%
175	Thoracic Neoplasms	10.2%
176	Thyroglossal Cyst	10.2%
177	Synovial Cyst	10.2%
178	Aberrant Crypt Foci	10.2%
179	Hodgkin Disease	10.2%
180	Lymphoma, Non-Hodgkin	10.2%
181	Paraneoplastic Encephalomyelitis	9.7%
182	Prolactinoma	9.7%
183	Growth Hormone-Secreting Pituitary Adenoma	9.7%
184	Carcinoid Heart Disease	9.7%
185	Mammary Neoplasms, Experimental	9.6%
186	Nephroblastoma	8.9%
187	Lymphomatoid Granulomatosis	8.6%
188	Primary amyloidosis	8.6%
189	Tuberous Sclerosis	8.5%
190	Carcinoma, Ovarian Epithelial	8.4%
191	Pheochromocytoma	8.3%
192	Digestive System Neoplasms	8.1%
193	Endocrine Gland Neoplasms	8.1%
194	Eye Neoplasms	8.1%
195	Nervous System Neoplasms	8.1%
196	Leukemia, Myelomonocytic, Chronic	7.8%
197	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	7.8%
198	Bone neoplasms	7.8%
199	Leukoplakia	7.8%
200	Lymphocele	7.8%
201	Pancreatic Cyst	7.8%
202	Skin Neoplasms	7.8%
203	Hematologic Neoplasms	7.8%
204	Barrett Esophagus	7.7%
205	Breast Cyst	7.7%
206	Actinic keratosis	7.7%
207	Mediastinal Cyst	7.7%
208	Neoplasm Invasiveness	7.7%
209	Neoplasm Metastasis	7.7%
210	Neoplasm Recurrence, Local	7.7%
211	Parovarian Cyst	7.7%
212	Pericardial Cyst	7.7%
213	Splenic Neoplasms	7.7%
214	Thymic Cyst	7.7%
215	Carcinogenesis	7.7%
216	Myxoid cyst	7.7%
217	Metastasis	7.7%
218	Optic Nerve Glioma	7.3%
219	Urticaria Pigmentosa	7.2%
220	Mesoblastic Nephroma	7.2%
221	Hemangioblastoma	7.2%
222	Lymphoma, Extranodal NK-T-Cell	7.2%
223	Vipoma	7.1%
224	Adenomatous Polyposis Coli	7%
225	Nasopharyngeal carcinoma	7%
226	insulinoma	6.9%
227	Adrenocortical carcinoma	6.9%
228	Waldenstrom Macroglobulinemia	6.4%
229	Multiple Myeloma	6.4%
230	Sturge-Weber Syndrome	6.4%
231	Multiple Endocrine Neoplasia Type 1	6.4%
232	Neoplasms, Fibrous Tissue	6.4%
233	Hydatidiform Mole	6.4%
234	Hemangioma, Cavernous	6.3%
235	Leukemia, T-Cell	6.3%
236	Leukemia, B-Cell	6.3%
237	Acoustic Neuroma	6.3%
238	neurofibroma	6.2%
239	Lymphoma, Follicular	6.2%
240	T-Cell Lymphoma	6.2%
241	Mantle cell lymphoma	6.2%
242	Corpus Luteum Cyst	6.1%
243	Ovarian Cysts	6.1%
244	Renal Cell Carcinoma	6%
245	Papillary Renal Cell Carcinoma	6%
246	Fibroadenoma	6%
247	Gastrinoma	5.9%
248	Glucagonoma	5.9%
249	Liver Neoplasms, Experimental	5.9%
250	Parathyroid Neoplasms	5.9%
251	Peritoneal Neoplasms	5.9%
252	Thyroid Neoplasm	5.9%
253	Thyroid carcinoma	5.9%
254	Carcinoma, Endometrioid	5.8%
255	Retroperitoneal Neoplasms	5.7%
256	Leukemia, Myeloid, Chronic-Phase	5.4%
257	granulosa cell tumor	5.2%
258	Choledochal Cyst	5.2%
259	Pancreatic Neoplasm	5.1%
260	Peutz-Jeghers Syndrome	5%
261	Tracheal Neoplasms	4.7%
262	Leukoplakia, Oral	4.6%
263	Paraneoplastic Cerebellar Degeneration	4.6%
264	Mouth Neoplasms	4.3%
265	Central Nervous System Neoplasms	4.3%
266	Vascular Neoplasms	4.3%
267	Thymus Neoplasms	4.3%
268	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	4.3%
269	Leukemia, Large Granular Lymphocytic	4.3%
270	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	4.3%
271	Lymphoma, T-Cell, Cutaneous	4.3%
272	Lymphoma, AIDS-Related	4.3%
273	Enteropathy-Associated T-Cell Lymphoma	4.3%
274	Primary Effusion Lymphoma	4.3%
275	Genital Neoplasms, Female	4.3%
276	Pancreatic Pseudocyst	4.3%
277	Lymphatic Metastasis	4.2%
278	Neoplasms, Unknown Primary	4.2%
279	Leukemic Infiltration	4.2%
280	Breast Neoplasms, Male	4.2%
281	Neoplasm Micrometastasis	4.2%
282	Triple Negative Breast Neoplasms	4.2%
283	Esophageal Neoplasms	4%
284	Limbic Encephalitis	3.9%
285	Denys-Drash Syndrome	3.8%
286	Leydig Cell Tumor	3.8%
287	Adrenal Gland Neoplasms	3.5%
288	Gastrointestinal Neoplasms	3.5%
289	Genital Neoplasms, Male	3.5%
290	Liver neoplasms	3.5%
291	Uveal Neoplasms	3.5%
292	Thyroid Nodule	3.5%
293	Lambert-Eaton Myasthenic Syndrome	3.5%
294	Testicular Neoplasms	3.5%
295	Urologic Neoplasms	3.5%
296	Sebaceous Gland Neoplasms	3.4%
297	Spinal Neoplasms	3.4%
298	Bone Marrow Neoplasms	3.4%
299	Polycystic Ovary Syndrome	3.4%
300	Mycosis Fungoides	3.3%
301	Lymphomatoid Papulosis	3.3%
302	Plasmablastic lymphoma	3.3%
303	Opsoclonus-Myoclonus Syndrome	3.1%
304	Burkitt Lymphoma	3.1%
305	Xeroderma Pigmentosum	3.1%
306	Myelitis, Transverse	2.8%
307	Meningeal Neoplasms	2.6%
308	ovarian neoplasm	2.5%
309	Nose Neoplasms	2.4%
310	Sezary Syndrome	2.4%
311	Palatal Neoplasms	2.2%
312	Pituitary Adenoma	2.2%
313	Pituitary Neoplasms	2.2%
314	Ear Neoplasms	2.2%
315	Eyelid Neoplasms	2.2%
316	Lung Neoplasms	2.2%
317	Pleural Neoplasms	2.2%
318	Cell Transformation, Viral	2.1%
319	Brain Neoplasms	2.1%
320	Salivary Gland Neoplasms	2.1%
321	Spinal Cord Neoplasms	2.1%
322	Tongue Neoplasms	2.1%
323	Uterine Neoplasms	2.1%
324	Vaginal Neoplasms	2.1%
325	Vulvar Neoplasms	2.1%
326	Uterine Cancer	2.1%
327	Fallopian Tube Neoplasms	2.1%
328	Zollinger-Ellison syndrome	1.9%
329	Pharyngeal Neoplasms	1.8%
330	Meningeal Carcinomatosis	1.8%
331	Central Nervous System Cysts	1.8%
332	Bile Duct Neoplasms	1.8%
333	gallbladder neoplasm	1.8%
334	Intestinal Neoplasms	1.8%
335	Penile Neoplasms	1.8%
336	Prostatic Neoplasms	1.8%
337	Stomach Neoplasms	1.8%
338	Polycythemia Vera	1.7%
339	Laryngeal neoplasm	1.6%
340	Bladder Neoplasm	1.5%
341	Kidney Neoplasm	1.5%
342	Ureteral Neoplasms	1.5%
343	Urethral Neoplasms	1.5%
344	Bronchial Neoplasms	1.5%
345	Multiple Pulmonary Nodules	1.5%
346	Supratentorial Neoplasms	1.4%
347	Endometrial Neoplasms	1.4%
348	Hypopharyngeal Neoplasms	1.2%
349	Pleural Effusion, Malignant	1.2%
350	Hypopharyngeal Cancer	1.2%
351	Parotid Neoplasms	1.2%
352	Prostatic Neoplasms, Castration-Resistant	1.2%
353	Nelson Syndrome	1.2%
354	Brain Stem Neoplasms	1.1%
355	Cecal Neoplasms	1%
356	Duodenal Neoplasms	1%
357	Choroid Plexus Papilloma	0.9%
358	Tonsillar Neoplasms	0.9%
359	Cerebellar Neoplasms	0.9%
360	Nasopharyngeal Neoplasms	0.9%
361	Colorectal Neoplasms	0.9%
362	Paranasal Sinus Neoplasms	0.8%
363	Radicular Cyst	0.8%
364	Appendiceal Neoplasms	0.8%
365	Colonic Neoplasms	0.8%
366	Rectal Neoplasms	0.8%
367	Maxillary Sinus Neoplasms	0.6%
368	Anus Neoplasms	0.6%
369	Sigmoid Neoplasms	0.6%

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