MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Brain Injuries

(UMLS:C0270611)

Definition:: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
UMLS ID:: C0270611
MeSH ID:: D001930

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.140.199|C10.900.300.087

Classification 2:

Name:

Wounds and Injuries
MeSH Tree Number(s):: C26.915.300.200

Synonym(s)

Brain Injuries

Acquired brain injury

BRAIN DAMAGE

Brain Damage

Brain Injury

Brain damage

Brain damage, NOS

Brain injury

Brain tissue injury

10.

Damage, brain

11.

Injury, Brain

12.

Injury;brain;acquired

13.

Injury;cerebral

14.

Intracerebral injury

15.

brain damage

16.

brain damages

17.

brain disorders injury

18.

brain injuries

19.

brain injury

Associated Drug(s)

	Name	Reference(s)	Data Source
1	1'-acetoxychavicol acetate	27481192	CTD
2	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	View details 3119180 9261828 10830409 11481687 12895461 17335811 19118628 20303391	CTD
3	2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine	2139189	CTD
4	2,5-hexanedione	19464574	CTD
5	2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine	15342103	CTD
6	3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer	9495877	CTD
7	3-dinitrobenzene	9039463	CTD
8	4-phenylbutyric acid	17459145	CTD
9	5,7-Dihydroxytryptamine	View details 6969865 17452372 19500572 19629448	CTD
10	5,7-dihydroxytryptamine creatinine	19309758	CTD
11	Acepromazine	15209296	CTD
12	Acetylcysteine	24299490	CTD
13	Alcohols	12425888 22960445	CTD
14	Aluminum Chloride	18482095 28552514	CTD
15	Amantadine	15769570	CTD
16	Aminophylline	11880191 12076843	CTD
17	Amoxapine	20702294	CTD
18	Amphetamine	20819043	CTD
19	Antazoline	12890517	CTD
20	Atorvastatin	17521631	CTD
21	Aurothioglucose	3084036 3084764 3928877	CTD
22	Boron	30997025	CTD
23	Bromocriptine	15684763	CTD
24	Cadmium Chloride	24299490	CTD
25	Caffeine	12681001	CTD
26	Carbamazepine	28267586	CTD
27	Carbon Monoxide	1447108 19520142	CTD
28	Clonazepam	3607518	CTD
29	Clozapine	10581982	CTD
30	Cocaine	View details 7554304 11853120 12425888 15541319 17202543 17618415 17904770 19217266	CTD
31	Colchicine	2924118	CTD
32	Colistin	30138604	CTD
33	Copper Sulfate	29054015	CTD
34	Cyclophosphamide	7194589	CTD
35	Cyclosporine	12942100	CTD
36	Cytarabine	15203180	CTD
37	DSP 4	19710996	CTD
38	Deoxycholic Acid	17188501	CTD
39	Dexamethasone	19236166 27655295 29935188	CTD
40	Diazepam	6639740 10928976	CTD
41	Dicyclomine	2331611	CTD
42	Diethylstilbestrol	1678068 20433902	CTD
43	Dinoprostone	3249309 20810888	CTD
44	Ditiocarb	22874009	CTD
45	Dizocilpine Maleate	8750036	CTD
46	Edaravone	18672383	CTD
47	Ellagic Acid	29455002	CTD
48	Enalapril	20600611	CTD
49	Estradiol	9972699 12757899	CTD
50	Fusaric Acid	31150628	CTD
51	Glycyrrhizic Acid	31150628	CTD
52	Halothane	10928976	CTD
53	Ibotenic Acid	3513907 12650838	CTD
54	Indomethacin	9500967 16223416	CTD
55	Inositol	8212011	CTD
56	Isoflurane	9039463 10928976	CTD
57	Kainic Acid	View details 3024077 7477442 7541299 7655348 9928847 9972699 10999512 14670625 18175345 21757006 22884490	CTD
58	Ketamine	View details 10487179 10928976 15291108 18063801	CTD
59	Levetiracetam	20026136	CTD
60	Levodopa	15342103	CTD
61	Lidoderm	17689565	CTD
62	Lithium Chloride	View details 7922540 9500967 15209296 18455351 19944736 21177194	CTD
63	Lithium	View details 1329122 1377589 3437996 9174239 9347520 9630518 10027775 10222443 10999512 11673025 11880191 12076843 12681001 12757899 15256179 17533168 20026136 20633040	CTD
64	Lovastatin	16400415	CTD
65	Magnesium Chloride	10506531	CTD
66	Magnesium Sulfate	19204407	CTD
67	Manganese Compounds	21985864	CTD
68	Melatonin	18289173	CTD
69	Memantine	27655295	CTD
70	Mercuric Chloride	22265750	CTD
71	Methamphetamine	19564919	CTD
72	Methylphenidate	1548250 19667974	CTD
73	Methylprednisolone	19236166	CTD
74	Minocycline	17406652 18836210	CTD
75	Naloxone	12575238	CTD
76	Nicotine	18803299	CTD
77	Nitric Oxide	9500967	CTD
78	Nitrites	19715735 19941068	CTD
79	Nitrous Oxide	10928976	CTD
80	O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate	27655295	CTD
81	Ouabain	7541299	CTD
82	Oxidopamine	View details 8836523 8951871 9585350 9628768 9767399 9819799 9890435 10600402 10869049 11215752 11300719 11312565 11391735 11425506 11723272 11739600 12127155 12419516 12429201 12473092 12524151 12535962 12614340 12957489 14511339 14526427 14618681 14673880 14697317 15056471 15065221 15094523 15207268 15342103 15474360 15502970 15641587 15659429 15703272 15899244 16023708 16095907 16139809 16269145 16325000 16365282 16531050 16540568 16621050 16706847 16817869 16971529 17027936 17055656 17116309 17188499 17192438 17241287 17329435 17335811 17359492 17452372 17553556 17588622 17588764 17596448 17630981 17652591 17660384 17662258 17884291 17900568 17920284 17933546 17997101 18281903 18428668 18638717 18650244 18687386 18707801 18717735 18762218 18947822 18952677 18988638 19010365 19039008 19115412 19118628 19146929 19187092 19283364 19302833 19309758 19357321 19369551 19371586 19393238 19399396 19399877 19419794 19463706 19500572 19520364 19633584 19636538 19660528 19710996 19733554 19771592 19895663 20050978 20060905 20079362 20200117 20232137 20434491 20456008 20615977 20623773 20631586 20736067 20858480 20882603 20888328 21085660 21088802 21129389 21163338 21183486 21195062	CTD
83	PD 117302	7894264	CTD
84	Pargyline	7953696	CTD
85	Pentobarbital	10928976 20699736	CTD
86	Phenobarbital	3607518	CTD
87	Phenylephrine	2375408	CTD
88	Pilocarpine	View details 1329122 1377589 1756784 2139189 3333612 3437996 3440212 3607518 3801895 6639740 7851985 7894264 7922540 8212011 8821376 8822702 8828581 9174239 9302530 9347520 9495877 9630518 10027775 10222443 10487179 10862938 10999512 11382382 11673025 11880191 12076843 12350385 12595191 12681001 12757899 12890517 13679415 15209296 15217378 15256179 16343452 16400415 17084066 17194568 17430409 17533168 17971868 18058944 18065154 18455351 18476527 18533134 18672383 19500573 19631748 19715735 19941068 20018232 20026136 20384764 20633040 20801723 20880321 21062633 21147076 21177194 21269288	CTD
89	Pioglitazone	20450929	CTD
90	Pregnanolone	15380490 15665606	CTD
91	Progesterone	View details 9972699 15380490 15665606 15845082 21549006	CTD
92	Propofol	14707428 17192529	CTD
93	Propylthiouracil	25825206	CTD
94	Quercetin	24148954 28040552	CTD
95	Quinolinic Acid	20450929 24211709 30130594	CTD
96	Raloxifene Hydrochloride	16580743	CTD
97	Remifentanil	11973195	CTD
98	Resveratrol	22314268 24675465 26936125	CTD
99	Rosiglitazone	18455351 18948087	CTD
100	Rotenone	View details 12504863 14645467 14766796 15635186 15854587 16118017 16219024 17459145 18197244 18289173 18803299 19385059 19626387	CTD
101	SCH 23390	2139189	CTD
102	Scopolamine	2331611 6639740 12536528	CTD
103	Selegiline	7953696	CTD
104	Simvastatin	View details 16054375 17521631 18826357 20833152	CTD
105	Soman	20003915 28866071	CTD
106	Spermine	21307247	CTD
107	Streptozocin	27566243	CTD
108	T-2 Toxin	29413859	CTD
109	Tacrine	9500967 19944736	CTD
110	Tacrolimus	12942100	CTD
111	Tapentadol	28499616	CTD
112	Theophylline	10565195	CTD
113	Thioctic Acid	19715735 21062633	CTD
114	Thiopental	1595344	CTD
115	Thiotepa	17904307	CTD
116	Thromboxane B2	3249309	CTD
117	Topiramate	17084066	CTD
118	Tramadol	28499616	CTD
119	U 69593	7894264	CTD
120	Urethane	9039463	CTD
121	Valproic Acid	View details 1414247 3607518 8808733 19626387	CTD
122	Vigabatrin	11673025 25554247	CTD
123	Vincristine	8413926	CTD
124	Vitamin E	14645467 19941068	CTD
125	Warfarin	25094061	CTD
126	Zolpidem	18226667	CTD
127	alpha-Chlorohydrin	14644096	CTD
128	alpha-Linolenic Acid	22884490	CTD
129	benzamide	14670625	CTD
130	bifenthrin	9039463	CTD
131	bisphenol A	30997025	CTD
132	caffeic acid	18482095	CTD
133	calpain inhibitor III	21985864	CTD
134	caramiphen	27655295	CTD
135	chlorpyrifos-ethyl	30267645	CTD
136	diphenyldiselenide	30267645	CTD
137	fasudil	8202986	CTD
138	ferric chloride	11391735	CTD
139	inositol 1-phosphate	8212011	CTD
140	malonic acid	15665418	CTD
141	phosphinothricin	19638430	CTD
142	polydatin	29130132	CTD
143	pralidoxime	27655295	CTD
144	reviparin	21534203	CTD
145	sesamin	15635186	CTD
146	sinapinic acid	17329848	CTD
147	sodium arsenite	29455002	CTD
148	tauroursodeoxycholic acid	12721362	CTD
149	tris(chloroethyl)phosphate	1676651	CTD
150	xaliproden	8413926	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Facial Injuries	40%
2	Coma, Post-Head Injury	35.5%
3	Meningoencephalitis	32.1%
4	Dementia, Vascular	29.2%
5	Subdural Effusion	29.1%
6	Spinal Cord Injuries	29.1%
7	Posterior Leukoencephalopathy Syndrome	28.9%
8	Posterior reversible encephalopathy syndrome	28.9%
9	Olfactory Nerve Injuries	28.8%
10	Multiple System Atrophy	28.7%
11	Dandy-Walker Syndrome	28.6%
12	Peripheral Nerve Injuries	28.4%
13	Lewy Body Disease	28.2%
14	Encephalomyelitis	27%
15	Akinetic Mutism	26.7%
16	Anoxic Encephalopathy	26.7%
17	Basal Ganglia Diseases	26.7%
18	Brain Damage, Chronic	26.7%
19	Cerebellar Diseases	26.7%
20	Encephalitis	26.7%
21	Encephalomalacia	26.7%
22	Epilepsy	26.7%
23	Hydrocephalus	26.7%
24	Congenital Hydrocephalus	26.7%
25	Hypothalamic Diseases	26.7%
26	Thalamic Diseases	26.7%
27	Intracranial Hypertension	26.7%
28	Aura	26.7%
29	Leukoencephalopathy	26.7%
30	Neuroaxonal Dystrophies	26.7%
31	Headache Disorders	26.7%
32	Intracranial Hypotension	26.7%
33	Brain Edema	26.7%
34	Brain Hypoxia	26.7%
35	Aqueductal Stenosis	26.7%
36	Parkinsonian Disorders	26.5%
37	Basal Ganglia Cerebrovascular Disease	26.4%
38	Subarachnoid Hemorrhage, Traumatic	26.2%
39	Myoclonic Epilepsy	26.1%
40	Epilepsy, Temporal Lobe	26.1%
41	Epilepsy, Rolandic	26.1%
42	Benign Rolandic Epilepsy	26.1%
43	Eye Injuries	25.6%
44	Facial Nerve Injuries	25.2%
45	Cerebrospinal Fluid Otorrhea	24.9%
46	Cerebrospinal Fluid Rhinorrhea	24.9%
47	Carotid Artery Injuries	24.7%
48	Parkinson Disease	24.4%
49	Marchiafava-Bignami Disease	24.2%
50	Vascular Headaches	24.1%
51	Eye Burns	24%
52	Hypoxia-Ischemia, Brain	24%
53	Meige Syndrome	23.7%
54	Cerebral Ventriculitis	23.7%
55	Juvenile Myoclonic Epilepsy	23.5%
56	Myoclonic Epilepsies, Progressive	23.5%
57	Brain Abscess	23%
58	Hematoma, Subdural	22.7%
59	Hematoma, Epidural, Cranial	22.7%
60	Cerebellar Neoplasms	22.7%
61	Leukomalacia, Periventricular	22.6%
62	Brain Hemorrhage, Traumatic	22.4%
63	Brain Neoplasms	22.1%
64	Huntington Disease	21.7%
65	Brain Diseases, Metabolic	21.6%
66	Cerebrovascular Disorders	21.6%
67	Cerebrovascular Insufficiency	21.6%
68	Dementia	21.6%
69	Striatonigral Degeneration	21.5%
70	Myelitis	21.3%
71	Ocular Motility Disorders	21.2%
72	Cyclophoria	21.2%
73	Basal Ganglia Hemorrhage	20.8%
74	Dystonia Musculorum Deformans	20.8%
75	Epidural Abscess	20.8%
76	Leukoencephalopathy, Progressive Multifocal	20.6%
77	Meningitis	20.3%
78	Movement Disorders	20.3%
79	Pachymeningitis	20.3%
80	Spinal Cord Diseases	20.3%
81	Neuroleptic Malignant Syndrome	20.1%
82	Myelinolysis, Central Pontine	20.1%
83	Brain Death	20.1%
84	Cerebral Palsy	19.8%
85	Epilepsies, Partial	19.8%
86	Epilepsy, Generalized	19.8%
87	Pseudotumor Cerebri	19.8%
88	Hypertensive Encephalopathy	19.8%
89	Simple Partial Seizures	19.8%
90	Epilepsy, Reflex	19.8%
91	Headache Disorders, Primary	19.8%
92	Headache Disorders, Secondary	19.8%
93	Medication overuse headache	19.8%
94	Creutzfeldt-Jakob disease	19.8%
95	Vertebral Artery Dissection	19.7%
96	Progressive supranuclear palsy	19.7%
97	Lafora Disease	19.6%
98	Unverricht-Lundborg Syndrome	19.6%
99	Leukoencephalitis, Acute Hemorrhagic	19.5%
100	Brain Concussion	19.5%
101	Hematoma, Subdural, Intracranial	19.5%
102	Hematoma, Subdural, Chronic	19.5%
103	Hematoma, Subdural, Acute	19.5%
104	Stiff-Person Syndrome	19.4%
105	Lupus Vasculitis, Central Nervous System	19.1%
106	Central Cord Syndrome	19%
107	MPTP Poisoning	18.9%
108	Prion Diseases	18.9%
109	Autonomic Dysreflexia	18.9%
110	Putaminal Hemorrhage	18.9%
111	Shy-Drager Syndrome	18.9%
112	Pituitary Apoplexy	18.9%
113	Pituitary Adenoma	18.7%
114	Pituitary Neoplasms	18.7%
115	Brain Infarction	18.6%
116	Infarction, Middle Cerebral Artery	18.5%
117	Infarction, Anterior Cerebral Artery	18.5%
118	Infarction, Posterior Cerebral Artery	18.5%
119	Carotid Artery, Internal, Dissection	18.4%
120	Limbic Encephalitis	18.1%
121	Amblyopia	18.1%
122	Corneal Scar	17.9%
123	Ophthalmoplegic Migraine	17.9%
124	Spinal Muscular Atrophy	17.8%
125	Progressive Muscular Atrophy	17.8%
126	Presenile dementia	17.7%
127	Senile dementia	17.7%
128	Cranial nerve diseases	17.5%
129	Demyelinating Diseases	17.5%
130	Demyelination	17.5%
131	Neuromuscular Diseases	17.5%
132	Chronobiology Disorders	17.5%
133	Poliomyelitis	17.1%
134	Encephalomyelitis, Acute Disseminated	16.9%
135	Central Nervous System Infection	16.9%
136	Subacute Combined Degeneration	16.8%
137	Cerebral Infarction	16.6%
138	Brain Stem Infarctions	16.6%
139	Amyotrophic Lateral Sclerosis	16.6%
140	Pituitary Diseases	16.6%
141	Post-Traumatic Headache	16.5%
142	Tension Headache	16.5%
143	Epilepsy, Complex Partial	16.5%
144	Migraine Disorders	16.5%
145	Abdominal Migraine	16.5%
146	Status Migrainosus	16.5%
147	Cervicogenic Headache	16.5%
148	Motor Neuron Disease	16.4%
149	Cerebellar Ataxia	16.3%
150	Supratentorial Neoplasms	16.3%
151	Miller Fisher Syndrome	16.3%
152	Canavan Disease	16%
153	Alexander Disease	16%
154	Hepatolenticular Degeneration	16%
155	Carotid Artery Diseases	15.9%
156	Brain Ischemia	15.9%
157	Cerebrovascular accident	15.9%
158	Kluver-Bucy Syndrome	15.9%
159	Vasospasm, Intracranial	15.9%
160	Intracranial Arterial Diseases	15.9%
161	Corneal Perforation	15.8%
162	Persistent Vegetative State	15.7%
163	Asterixis	15.7%
164	Ballismus	15.7%
165	Lateral Medullary Syndrome	15.7%
166	Friedreich Ataxia	15.5%
167	Meningitis, Bacterial	15.5%
168	Meningitis, Fungal	15.5%
169	Moyamoya Disease	15.5%
170	Amnesia, Transient Global	15.1%
171	Paraneoplastic Cerebellar Degeneration	15.1%
172	Vasculitis, Central Nervous System	15.1%
173	Toxoplasmosis, Cerebral	15%
174	Conus Medullaris Syndrome	14.9%
175	Cluster Headache	14.8%
176	Migraine with Aura	14.8%
177	Familial Hemiplegic Migraine	14.8%
178	Chronic Paroxysmal Hemicrania	14.8%
179	SUNCT Syndrome	14.8%
180	Paroxysmal Hemicrania	14.8%
181	Polyradiculoneuropathy	14.5%
182	Polyradiculoneuritis	14.5%
183	Restless Legs Syndrome	14.4%
184	Myelitis, Transverse	14.4%
185	Pneumocephalus	14.2%
186	Nervous System Neoplasms	14.1%
187	Neurologic Manifestations	14.1%
188	Neurotoxicity Syndromes	14.1%
189	Epilepsy, Post-Traumatic	14%
190	Chronic Fatigue Syndrome	14%
191	Brain Stem Neoplasms	13.5%
192	Complex Regional Pain Syndromes	13.5%
193	Empty Sella Syndrome	13.4%
194	Hyperpituitarism	13.4%
195	Hypopituitarism	13.4%
196	Hypophysitis	13.4%
197	Arachnoiditis	13.3%
198	Aseptic Meningitis	13.3%
199	Syringomyelia	13.3%
200	Essential Tremor	13.3%
201	Familial Tremor	13.3%
202	Pneumorrhachis	13.3%
203	Writer's Cramp	13.3%
204	Reye Syndrome	13.3%
205	Spinal Cord Neoplasms	13.3%
206	Intracranial Embolism and Thrombosis	13.2%
207	Hepatic Encephalopathy	13.2%
208	Cerebral Arterial Diseases	13.1%
209	Vertebrobasilar Insufficiency	13.1%
210	Basilar Artery Stenosis	13.1%
211	Vertebral Artery Stenosis	13.1%
212	Intracranial Hemorrhage, Hypertensive	13.1%
213	Transient Cerebral Ischemia	13.1%
214	Tuberculosis, Meningeal	13%
215	Opsoclonus-Myoclonus Syndrome	12.7%
216	Subacute Sclerosing Panencephalitis	12.6%
217	Mitochondrial Encephalomyopathies	12.3%
218	Choroid Plexus Papilloma	12.1%
219	MELAS Syndrome	12.1%
220	Frontotemporal dementia	12.1%
221	Adrenoleukodystrophy	12.1%
222	Guillain-Barre Syndrome	12%
223	Dyskinesia, Drug-Induced	11.9%
224	Sleep Wake Disorders	11.9%
225	Hyperprolactinemia	11.9%
226	Akathisia, Drug-Induced	11.8%
227	Subclavian Steal Syndrome	11.7%
228	Pick Disease of the Brain	11.7%
229	Ataxia Telangiectasia	11.6%
230	Brain Diseases, Metabolic, Inborn	11.4%
231	Frostbite	11.3%
232	Myasthenia Gravis	11.2%
233	Scrapie	11.2%
234	Causalgia	11%
235	Chorea	11%
236	Carotid Stenosis	11%
237	Intracranial Aneurysm	11%
238	Auditory Perceptual Disorders	10.9%
239	Intracranial Arteriosclerosis	10.9%
240	Cerebral Atherosclerosis	10.9%
241	Subarachnoid Hemorrhage	10.9%
242	Cerebral Arteriosclerosis	10.9%
243	Cerebral Hemorrhage	10.9%
244	Cerebral Thrombosis	10.9%
245	Intracranial Embolism	10.9%
246	Intracranial Thrombosis	10.9%
247	Alice in Wonderland Syndrome	10.8%
248	Central Nervous System Fungal Infections	10.8%
249	Spinal Cord Vascular Diseases	10.8%
250	Progressive bulbar palsy	10.7%
251	Bulbar palsy	10.7%
252	Lambert-Eaton Myasthenic Syndrome	10.4%
253	West Nile Fever	10.4%
254	Meningitis, Cryptococcal	10.3%
255	Meningitis, Listeria	10.3%
256	Meningitis, Haemophilus	10.2%
257	Meningitis, Pneumococcal	10.2%
258	Dysautonomia	10.2%
259	Vagus Nerve Disorder	10.2%
260	Glossopharyngeal Neuralgia	10.2%
261	Abducens Nerve Diseases	10.2%
262	Heavy Metal Poisoning, Nervous System	10.2%
263	Neuromuscular Junction Diseases	10.2%
264	Tauopathies	10.2%
265	Trochlear Nerve Diseases	10.2%
266	Peripheral Nervous System Diseases	10.2%
267	Neuromyelitis Optica	10.1%
268	Acromegaly	9.9%
269	Sleep Disorders, Circadian Rhythm	9.9%
270	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	9.9%
271	Wernicke Encephalopathy	9.9%
272	AIDS Dementia Complex	9.9%
273	Torticollis	9.8%
274	Cerebral Amyloid Angiopathy	9.8%
275	Sinus Thrombosis, Intracranial	9.7%
276	Botulism	9.6%
277	Central Nervous System Cysts	9.6%
278	Carotid Artery Thrombosis	9.3%
279	Reflex Sympathetic Dystrophy	9.3%
280	Nocturnal Myoclonus Syndrome	9.3%
281	Giant Cell Arteritis	9.2%
282	Temporal Arteritis	9.2%
283	Cavernous Sinus Thrombosis	9.2%
284	Sagittal Sinus Thrombosis	9.2%
285	Central Nervous System Bacterial Infections	9.1%
286	Refsum Disease	9%
287	Kernicterus	8.9%
288	Multiple Sclerosis	8.8%
289	Athletic Injuries	8.8%
290	Hand Injuries	8.8%
291	Soft Tissue Injuries	8.8%
292	Sprain	8.8%
293	Sprains and Strains	8.8%
294	Tendon Injuries	8.8%
295	Laceration	8.8%
296	Wounds, Penetrating	8.8%
297	Heat Cramps	8.8%
298	Rupture	8.8%
299	Tardive Dyskinesia	8.7%
300	Horner Syndrome	8.6%
301	Myopathy	8.5%
302	Optic Neuropathy	8.5%
303	Carpal Tunnel Syndrome	8.2%
304	Crush syndrome	8.2%
305	Facial Nerve Diseases	8.2%
306	Femoral Fractures	8.2%
307	Parasomnia	8.2%
308	Tibial Fractures	8.2%
309	Dyssomnias	8.2%
310	Vestibulocochlear Nerve Diseases	8.1%
311	Decerebrate State	8.1%
312	Hemiparesis	8.1%
313	Hydranencephaly	8.1%
314	Meningism	8.1%
315	Neural Tube Defects	8.1%
316	Paresis	8.1%
317	Seizures	8.1%
318	Sensation Disorders	8.1%
319	Tethered Cord Syndrome	8.1%
320	Central Nervous System Neoplasms	8.1%
321	Complex partial seizures	8.1%
322	Iniencephaly	8.1%
323	Craniorachischisis	8.1%
324	Exencephaly	8.1%
325	Monoparesis	8.1%
326	Septo-Optic Dysplasia	8.1%
327	Cortical Dysplasia	8.1%
328	Neurogenic Inflammation	8.1%
329	Gait Disorders, Neurologic	8.1%
330	Neuromuscular Manifestations	8.1%
331	Malformations of Cortical Development	8.1%
332	Sweating, Gustatory	8.1%
333	Auriculotemporal Syndrome	8.1%
334	Myasthenia Gravis, Autoimmune, Experimental	8%
335	Medial Tibial Stress Syndrome	8%
336	Spinal Cord Ischemia	7.9%
337	Fabry Disease	7.9%
338	Brachial Plexus Neuritis	7.9%
339	Neuralgic Amyotrophy	7.9%
340	Nelson Syndrome	7.9%
341	Hip Fractures	7.9%
342	Tuberculosis, Central Nervous System	7.9%
343	Charcot-Marie-Tooth Disease	7.8%
344	Acrodynia	7.7%
345	Ophthalmoplegia	7.7%
346	External Ophthalmoplegia	7.7%
347	Jet Lag Syndrome	7.5%
348	Prolactinoma	7.4%
349	Growth Hormone-Secreting Pituitary Adenoma	7.4%
350	Tuberous Sclerosis	7.3%
351	Trauma, Nervous System	7.2%
352	Galactosemias	7.2%
353	Urea Cycle Disorders, Inborn	7.2%
354	Tyrosinemias	7.2%
355	Tarsal Tunnel Syndrome	7.2%
356	Cauda Equina Syndrome	7.2%
357	Cubital Tunnel Syndrome	7.1%
358	Bites and Stings	7%
359	Extravasation of Diagnostic and Therapeutic Materials	7%
360	Vascular System Injuries	7%
361	Tympanic Membrane Perforation	7%
362	Tooth Injuries	7%
363	Pupil Disorders	7%
364	Neurobehavioral Manifestations	7%
365	Asphyxia	6.9%
366	Esophageal Perforation	6.9%
367	Shock, Traumatic	6.9%
368	Self Mutilation	6.9%
369	Hip Dislocation	6.8%
370	Shoulder Dislocation	6.8%
371	Splenic Rupture	6.8%
372	Paraneoplastic Encephalomyelitis	6.8%
373	Hip Dysplasia	6.8%
374	Chilblains	6.8%
375	Spinal Fractures	6.8%
376	Vocal Cord Paralysis	6.8%
377	Uveomeningoencephalitic Syndrome	6.7%
378	Sturge-Weber Syndrome	6.7%
379	Vertigo	6.7%
380	Alcohol-Induced Disorders, Nervous System	6.7%
381	Neuritis	6.7%
382	Polyneuritis	6.7%
383	Radiculitis	6.7%
384	Polyneuropathy	6.7%
385	Mononeuritis	6.7%
386	Mononeuropathies	6.7%
387	Brachial Plexus Neuropathies	6.7%
388	Radiculopathy	6.7%
389	Mononeuropathy Multiplex	6.7%
390	Nerve Root Compression	6.7%
391	Myotonia Congenita	6.6%
392	Neuroaspergillosis	6.6%
393	Neuritis, Autoimmune, Experimental	6.6%
394	Anterior Spinal Artery Syndrome	6.6%
395	Gait Ataxia	6.6%
396	Homocystinuria	6.5%
397	Multiple Sclerosis, Chronic Progressive	6.5%
398	Multiple Sclerosis, Relapsing-Remitting	6.5%
399	Leigh Disease	6.5%
400	Myotonic Dystrophy	6.3%
401	Menkes Kinky Hair Syndrome	6.2%
402	neurofibroma	6%
403	Sciatica	6%
404	Pseudorabies	5.9%
405	Voice Disorders	5.9%
406	Voice Disturbance	5.9%
407	Alcohol Withdrawal Seizures	5.9%
408	Carbamoyl-Phosphate Synthase I Deficiency Disease	5.8%
409	Smith-Magenis syndrome	5.8%
410	Akathisia	5.7%
411	Restlessness	5.7%
412	Psychomotor Agitation	5.7%
413	Drowning	5.7%
414	Dural Arteriovenous Fistula	5.7%
415	Optic Nerve Glioma	5.7%
416	Neurosyphilis	5.6%
417	Toxoplasmosis, Congenital	5.5%
418	Malaria, Cerebral	5.5%
419	Neurocysticercosis	5.5%
420	Myositis	5.4%
421	Optic Atrophy	5.4%
422	Optic Neuritis	5.4%
423	Papilledema	5.4%
424	Strabismus	5.4%
425	Tolosa-Hunt Syndrome	5.4%
426	Isaacs syndrome	5.4%
427	Arsenic Poisoning	5.4%
428	Myotonic Disorders	5.4%
429	Myasthenic Syndromes, Congenital	5.4%
430	Diabetic Neuropathies	5.3%
431	Facial Neuralgia	5.3%
432	Diabetic Amyotrophy	5.3%
433	Diabetic Autonomic Neuropathy	5.3%
434	Sleep Talking	5.3%
435	Manganese Poisoning	5.3%
436	Sleep Disorders, Intrinsic	5.3%
437	Iliotibial Band Syndrome	5.3%
438	Orthostatic intolerance	5.3%
439	Gait Apraxia	5.3%
440	Anosmia	5.3%
441	Ataxia	5.3%
442	Athetosis	5.3%
443	Catalepsy	5.3%
444	Dystonia	5.3%
445	Hemiplegia	5.3%
446	Locked-In Syndrome	5.3%
447	Meningeal Neoplasms	5.3%
448	Meningomyelocele	5.3%
449	Muscle Hypertonia	5.3%
450	Muscle hypotonia	5.3%
451	Myoclonus	5.3%
452	Myotonia	5.3%
453	Neuralgia	5.3%
454	Paraplegia	5.3%
455	Pseudobulbar Palsy	5.3%
456	Quadriplegia	5.3%
457	Spasm	5.3%
458	Spastic Paraplegia	5.3%
459	Status Epilepticus	5.3%
460	Taste Disorders	5.3%
461	Tremor	5.3%
462	Spina Bifida	5.3%
463	Monoplegia	5.3%
464	Hypokinesia	5.3%
465	Paraparesis	5.3%
466	Bradykinesia	5.3%
467	Waxy flexibility	5.3%
468	Action Tremor	5.3%
469	Resting Tremor	5.3%
470	Dysosmia	5.3%
471	Quadriparesis	5.3%
472	Mercury Poisoning, Nervous System	5.3%
473	Olfaction Disorders	5.3%
474	Myokymia	5.3%
475	Lead Poisoning, Nervous System	5.3%
476	Vestibular Neuronitis	5.3%
477	Somatosensory Disorders	5.3%
478	Neuropathic pain	5.3%
479	Hyperkinesia	5.3%
480	Intention tremor	5.3%
481	Glycogen storage disease type II	5.3%
482	Alstrom Syndrome	5.2%
483	Waterhouse-Friderichsen Syndrome	5.1%
484	Human Bite	5.1%
485	Brain Diseases	5.1%
486	Contusions	5.1%
487	Decompression Sickness	5.1%
488	Finger Injuries	5.1%
489	Flail Chest	5.1%
490	Fractures, Closed	5.1%
491	Pathological fracture	5.1%
492	Heart Injuries	5.1%
493	Heat Exhaustion	5.1%
494	Heat Stroke	5.1%
495	Knee Injuries	5.1%
496	Foot Injuries	5.1%
497	Decapitation	5.1%
498	Ankle Fracture	5.1%
499	Avulsion fracture	5.1%
500	Compression fracture	5.1%
501	Osteoporotic Fractures	5.1%
502	Zellweger Syndrome	5.1%
503	Reflex, Abnormal	5%
504	Hyporeflexia	5%
505	Hyperreflexia	5%
506	Sciatic Neuropathy	5%
507	Ulnar Neuropathies	5%
508	Lesion of Sciatic Nerve	5%
509	Ulnar Neuritis	5%
510	Radial nerve compression	5%
511	Radial Tunnel Syndrome	5%
512	Peroneal Neuropathies	5%
513	Radial Neuropathy	5%
514	Median Neuropathy	5%
515	Sciatic Nerve Palsy	5%
516	Femoral Neuropathy	5%
517	Tibial Neuropathy	5%
518	Ulnar Nerve Palsy	5%
519	Postural Orthostatic Tachycardia Syndrome	5%
520	Radial nerve palsy	5%
521	Lyme Neuroborreliosis	4.9%
522	Radiation injury	4.8%
523	Hand-Arm Vibration Syndrome	4.7%
524	Amyloid Neuropathies, Familial	4.6%
525	Vision Disorders	4.6%
526	Metamorphopsia	4.6%
527	Visual Impairment	4.6%
528	Fibromyalgia	4.5%
529	Optic Neuropathy, Ischemic	4.5%
530	Anterior Ischemic Optic Neuropathy	4.5%
531	Gaucher Disease	4.5%
532	Facial Hemiatrophy	4.5%
533	Melkersson-Rosenthal Syndrome	4.5%
534	Mitochondrial Myopathies	4.5%
535	Anisocoria	4.5%
536	Confusion	4.5%
537	Facial paralysis	4.5%
538	Lethargy	4.5%
539	Memory Disorders	4.5%
540	Muscle Cramp	4.5%
541	Perceptual Disorders	4.5%
542	Psychomotor Disorders	4.5%
543	Tonic Pupil	4.5%
544	Eosinophilia-Myalgia Syndrome	4.5%
545	Anhedonia	4.5%
546	Disorientation	4.5%
547	Facial Paresis	4.5%
548	Memory Loss	4.5%
549	Hemisensory Neglect	4.5%
550	Dysacusis	4.5%
551	Classical Lissencephalies and Subcortical Band Heterotopias	4.5%
552	Brain Injuries	4.4%
553	Sleep Bruxism	4.4%
554	Anencephaly	4.4%
555	Meningocele	4.4%
556	Muscular Atrophy	4.4%
557	Respiratory Paralysis	4.4%
558	Splenosis	4.4%
559	Encephalocele	4.4%
560	Tetany	4.4%
561	Acoustic Neuroma	4.4%
562	Tay-Sachs Disease	4.3%
563	Brain Contusion	4.2%
564	Polyradiculopathy	4.1%
565	Craniocerebral Trauma	4.1%
566	Tendinitis	4.1%
567	Lung Injury	4.1%
568	Tendinopathy	4.1%
569	Alexia	4.1%
570	Dyslexia	4.1%
571	Foreign-Body Reaction	4.1%
572	Insect Bites and Stings	4.1%
573	Paralysis, Obstetric	4.1%
574	Sunburn	4.1%
575	Tooth Avulsion	4.1%
576	Niemann-Pick Disease, Type C	4%
577	Near Drowning	4%
578	Osteoradionecrosis	4%
579	Thoracic Outlet Syndrome	4%
580	Esotropia	4%
581	Exotropia	4%
582	Hypotension, Orthostatic	4%
583	Sleep Apnea Syndromes	4%
584	Polymyositis	4%
585	Post-Exercise Hypotension	4%
586	Disorders of Excessive Somnolence	3.9%
587	Sleep Initiation and Maintenance Disorders	3.9%
588	Night Terrors	3.9%
589	Somnambulism	3.9%
590	Trigeminal Nerve Disorder	3.9%
591	Transient Insomnia	3.9%
592	Sleep Paralysis	3.9%
593	Chronic Insomnia	3.9%
594	REM Sleep Behavior Disorder	3.9%
595	Hypersomnia	3.9%
596	Dermal Sinus	3.9%
597	Dysgeusia	3.9%
598	Formication	3.9%
599	Hyperalgesia	3.9%
600	Hyperesthesia	3.9%
601	Hypesthesia	3.9%
602	Language Disorders	3.9%
603	Numbness	3.9%
604	Paresthesia	3.9%
605	Paraparesis, Spastic	3.9%
606	Spina Bifida Cystica	3.9%
607	Trismus	3.9%
608	Spina Bifida Occulta	3.9%
609	Epilepsia Partialis Continua	3.9%
610	Hypogeusia	3.9%
611	Meningeal Carcinomatosis	3.9%
612	Brown-Sequard Syndrome	3.9%
613	Lissencephaly	3.9%
614	Polymicrogyria	3.9%
615	Pachygyria	3.9%
616	Schizencephaly	3.9%
617	Lockjaw	3.9%
618	Allodynia	3.9%
619	Lead Poisoning, Nervous System, Childhood	3.9%
620	Lead Poisoning, Nervous System, Adult	3.9%
621	Periventricular Nodular Heterotopia	3.9%
622	Ageusia	3.9%
623	Duane Retraction Syndrome	3.9%
624	Consciousness Disorders	3.9%
625	Mental Retardation	3.9%
626	Muscle Weakness	3.9%
627	Depressed Level of Consciousness	3.9%
628	Mental deficiency	3.9%
629	Intellectual Disability	3.9%
630	Mobius Syndrome	3.8%
631	Bell Palsy	3.8%
632	Neurofibrosarcoma	3.8%
633	Catatonia	3.8%
634	Herpes Zoster Oticus	3.8%
635	Familial Periodic Paralysis	3.8%
636	Aphonia	3.8%
637	Sleep Deprivation	3.8%
638	Dysphonia	3.8%
639	Kearns-Sayre syndrome	3.7%
640	Optic Atrophy, Hereditary, Leber	3.6%
641	Neoplasms, Radiation-Induced	3.5%
642	Muscular Dystrophy	3.4%
643	Uterine Rupture	3.4%
644	Congenital nystagmus	3.4%
645	Orbital Myositis	3.4%
646	Pseudarthrosis	3.3%
647	Smoke Inhalation Injury	3.3%
648	Diplopia	3.3%
649	Muscle Rigidity	3.3%
650	Muscle Spasticity	3.3%
651	Scotoma	3.3%
652	Photophobia	3.3%
653	Cogwheel Rigidity	3.3%
654	Hemifacial Spasm	3.3%
655	Amaurosis	3.3%
656	Blindness	3.3%
657	Nuchal Rigidity	3.3%
658	Pyomyositis	3.3%
659	Myalgia	3.3%
660	Agnosia	3.3%
661	Apraxias	3.3%
662	Hallucinations	3.3%
663	Hemianopsia	3.3%
664	Hyperacusis	3.3%
665	Tinnitus	3.3%
666	Visual Agnosia	3.3%
667	Anosognosia	3.3%
668	Wernicke-Korsakoff Syndrome	3.3%
669	Phonophobia	3.3%
670	Hearing Loss	3.3%
671	Neuronal Ceroid-Lipofuscinoses	3.3%
672	Brain Injuries, Diffuse	3.3%
673	Sleep Apnea, Obstructive	3.3%
674	Sleep Apnea, Central	3.3%
675	Traumatic Brain Injury	3.3%
676	Sarcopenia	3.3%
677	Narcolepsy	3.3%
678	Trigeminal Neuralgia	3.3%
679	Kleine-Levin Syndrome	3.3%
680	Agraphia	3.3%
681	Anomia	3.3%
682	Cluttering	3.3%
683	Language Development Disorders	3.3%
684	Speech Disorders	3.3%
685	Syncope	3.3%
686	Stupor	3.3%
687	Dysgraphia	3.3%
688	Presyncope	3.3%
689	Dyslalia	3.3%
690	Aicardi's syndrome	3%
691	Hoarseness	3%
692	Cockayne Syndrome	3%
693	Alcohol Withdrawal Delirium	2.9%
694	Cataplexy	2.9%
695	Aphasia	2.9%
696	Articulation Disorders	2.9%
697	Echolalia	2.9%
698	Stuttering	2.9%
699	Dysphasia	2.9%
700	Cardiotoxicity	2.9%
701	Leukemia, Radiation-Induced	2.9%
702	Radiation Pneumonitis	2.9%
703	Radiation Fibrosis	2.9%
704	Amnesia	2.9%
705	Delirium	2.9%
706	Dissociative Amnesia	2.9%
707	Color blindness	2.9%
708	Global Amnesia	2.9%
709	Aortic Rupture	2.8%
710	Cri-du-Chat Syndrome	2.8%
711	Down Syndrome	2.8%
712	Trisomy 21	2.8%
713	POEMS Syndrome	2.8%
714	Meningioma	2.8%
715	Williams Syndrome	2.8%
716	Microcephaly	2.8%
717	Macrocephaly	2.8%
718	Hypokalemic periodic paralysis	2.8%
719	Porencephaly	2.8%
720	Dysarthria	2.8%
721	Welander Distal Myopathy	2.7%
722	Amaurosis Fugax	2.7%
723	Blindness, Cortical	2.7%
724	Dyscalculia	2.7%
725	Rett Syndrome	2.7%
726	Deafness	2.7%
727	Hearing Loss, Sudden	2.7%
728	Gerstmann Syndrome	2.7%
729	Hearing Loss, Bilateral	2.7%
730	Hearing Loss, High-Frequency	2.7%
731	Hearing Loss, Mixed Conductive-Sensorineural	2.7%
732	Prosopagnosia	2.7%
733	Apraxia, Ideomotor	2.7%
734	Charles Bonnet Syndrome	2.7%
735	Hearing Loss, Unilateral	2.7%
736	Complete Hearing Loss	2.7%
737	Alien Hand Syndrome	2.7%
738	Deaf Mutism	2.7%
739	Diffuse Axonal Injury	2.7%
740	Granuloma, Foreign-Body	2.7%
741	Enthesopathy	2.7%
742	Holoprosencephaly	2.6%
743	Uterine Perforation	2.6%
744	Abnormalities, Radiation-Induced	2.5%
745	Prader-Willi Syndrome	2.5%
746	Mutism	2.5%
747	Selective Mutism	2.5%
748	Radiation Injuries, Experimental	2.5%
749	Phantom pain	2.4%
750	Phantom Limb Pain	2.4%
751	Dermatomyositis	2.4%
752	Muscular Dystrophy, Duchenne	2.4%
753	Retrograde amnesia	2.3%
754	Amnesia, Anterograde	2.3%
755	Alexia, Pure	2.3%
756	Fragile X Syndrome	2%
757	Rubinstein-Taybi Syndrome	2%
758	Mucopolysaccharidosis II	1.5%

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