MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Tolosa-Hunt Syndrome

(UMLS:C0040381)

Definition:: An idiopathic syndrome characterized by the formation of granulation tissue in the anterior cavernous sinus or superior orbital fissure, producing a painful ophthalmoplegia. (Adams et al., Principles of Neurology, 6th ed, p271)
UMLS ID:: C0040381
MeSH ID:: D020333

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.292.562.900

Classification 2:

Name:

Eye Diseases
MeSH Tree Number(s):: C11.590.905

Synonym(s)

Tolosa-Hunt Syndrome

Tolosa-Hunt syndrome

syndrome tolosa-hunt

tolosa hunt syndrome

tolosa-hunt syndrome

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Progesterone	FAERS: 2 Canada Vigilance: 2	Canada Vigilance US FAERS
2	Desogestrel	FAERS: 1	US FAERS
3	Formoterol Fumarate	FAERS: 1	US FAERS
4	Pregabalin	FAERS: 1	US FAERS
5	Ambroxol		OFFSIDES
6	Indinavir		OFFSIDES
7	Ketotifen		OFFSIDES
8	Leuprolide		OFFSIDES
9	Nevirapine		OFFSIDES
10	Opalmon		OFFSIDES
11	Stavudine		OFFSIDES
12	Theophylline		OFFSIDES
13	Verapamil		OFFSIDES
14	alfacalcidol		OFFSIDES
15	imidapril		OFFSIDES
16	limaprost		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Strabismus	44.8%
2	Duane Retraction Syndrome	34.5%
3	Esotropia	32.8%
4	Exotropia	32.8%
5	Ophthalmoplegia	31.6%
6	External Ophthalmoplegia	31.6%
7	Optic Neuropathy	27.3%
8	Congenital nystagmus	26.5%
9	Ophthalmoplegic Migraine	25.3%
10	Opsoclonus-Myoclonus Syndrome	23.5%
11	Miller Fisher Syndrome	21.8%
12	Vagus Nerve Disorder	20.9%
13	Glossopharyngeal Neuralgia	20.9%
14	Abducens Nerve Diseases	20.9%
15	Trochlear Nerve Diseases	20.9%
16	Progressive supranuclear palsy	19.4%
17	Optic Atrophy	17.2%
18	Optic Neuritis	17.2%
19	Papilledema	17.2%
20	Facial Nerve Diseases	15.8%
21	Vestibulocochlear Nerve Diseases	15.5%
22	Olfactory Nerve Injuries	15%
23	Asthenopia	14.6%
24	Conjunctival Diseases	14.6%
25	Corneal Diseases	14.6%
26	Eyelid Diseases	14.6%
27	Lacrimal Apparatus Diseases	14.6%
28	Lens Diseases	14.6%
29	Ocular Hypertension	14.6%
30	Ocular Hypotension	14.6%
31	Retinal Diseases	14.6%
32	Scleral Diseases	14.6%
33	Vitreous Detachment	14.6%
34	Posterior Vitreous Detachment	14.6%
35	Retinal Degeneration	14%
36	Optic Neuropathy, Ischemic	13.9%
37	Anterior Ischemic Optic Neuropathy	13.9%
38	Pupil Disorders	12.9%
39	Facial Nerve Injuries	12.9%
40	Demyelinating Diseases	12.2%
41	Demyelination	12.2%
42	Neuromuscular Diseases	12.2%
43	Chronobiology Disorders	12.2%
44	Xerophthalmia	12.1%
45	Low Tension Glaucoma	12.1%
46	Iridocorneal endothelial syndrome	12.1%
47	Retinal Dysplasia	11.9%
48	Kearns-Sayre syndrome	11.4%
49	Vision Disorders	11.2%
50	Metamorphopsia	11.2%
51	Visual Impairment	11.2%
52	Blepharophimosis	11.1%
53	Uveal Neoplasms	11.1%
54	Eyelid Neoplasms	11%
55	Retinal Hemorrhage	11%
56	Eye Abnormalities	10.9%
57	Eye Infection	10.9%
58	Eye Manifestations	10.9%
59	Eye Neoplasms	10.9%
60	Aniridia	10.8%
61	Keratoconjunctivitis Sicca	10.7%
62	Motor Neuron Disease	10.5%
63	Corneal Scar	10.5%
64	Eye Injuries	10.4%
65	Facial Neuralgia	10.2%
66	Keratoconjunctivitis	10.2%
67	Chorioretinitis	10.1%
68	Vestibular Neuronitis	10.1%
69	Multiple System Atrophy	9.6%
70	Corneal Ulcer	9.6%
71	Neuromyelitis Optica	9.6%
72	Choroid Hemorrhage	9.5%
73	Color blindness	9.5%
74	Trauma, Nervous System	9.4%
75	Pars Planitis	9.4%
76	Angioid Streaks	9.3%
77	Anisometropia	9.3%
78	Aphakia	9.3%
79	Astigmatism	9.3%
80	Blepharitis	9.3%
81	Blepharoptosis	9.3%
82	Blepharospasm	9.3%
83	Choroid Diseases	9.3%
84	Conjunctivitis	9.3%
85	Corneal edema	9.3%
86	Corneal Opacity	9.3%
87	Dacryocystitis	9.3%
88	Dry Eye Syndromes	9.3%
89	Ectropion	9.3%
90	Enophthalmos	9.3%
91	Entropion	9.3%
92	Episcleritis	9.3%
93	Exophthalmos	9.3%
94	Glaucoma	9.3%
95	Iris Diseases	9.3%
96	Keratitis	9.3%
97	Keratoconus	9.3%
98	Lacrimal Duct Obstruction	9.3%
99	Lens dislocation	9.3%
100	Lens Subluxation	9.3%
101	Mydriasis	9.3%
102	Myopia	9.3%
103	Presbyopia	9.3%
104	Pterygium	9.3%
105	Retinal Detachment	9.3%
106	Retinitis	9.3%
107	Scleritis	9.3%
108	Uveitis	9.3%
109	Corneal Neovascularization	9.3%
110	Orbital Pseudotumor	9.3%
111	Cataract	9.3%
112	Pinguecula	9.3%
113	Trichiasis	9.3%
114	Stiff-Person Syndrome	9.2%
115	Nervous System Neoplasms	9.1%
116	Neurologic Manifestations	9.1%
117	Neurotoxicity Syndromes	9.1%
118	Retinitis Pigmentosa	8.8%
119	Pigmentary retinopathy	8.8%
120	Choroiditis	8.8%
121	Iridocyclitis	8.8%
122	Iritis	8.8%
123	Encephalomyelitis	8.6%
124	Prion Diseases	8.6%
125	Autonomic Dysreflexia	8.6%
126	Complex Regional Pain Syndromes	8.6%
127	Polyradiculoneuropathy	8.6%
128	Polyradiculoneuritis	8.6%
129	Eye Hemorrhage	8.5%
130	Amblyopia	8.4%
131	Horner Syndrome	8.4%
132	Restless Legs Syndrome	8.3%
133	Facial Hemiatrophy	8.2%
134	Melkersson-Rosenthal Syndrome	8.2%
135	Uveomeningoencephalitic Syndrome	8.2%
136	Anisocoria	8.2%
137	Tonic Pupil	8.2%
138	Spinal Muscular Atrophy	8.1%
139	Progressive Muscular Atrophy	8.1%
140	Optic Nerve Glioma	8%
141	Hordeolum	7.9%
142	Optic Atrophy, Hereditary, Leber	7.9%
143	Corneal Perforation	7.9%
144	Vocal Cord Paralysis	7.8%
145	Meningoencephalitis	7.8%
146	Subacute Combined Degeneration	7.8%
147	Parkinson Disease	7.7%
148	Marchiafava-Bignami Disease	7.7%
149	Amyotrophic Lateral Sclerosis	7.7%
150	Trigeminal Nerve Disorder	7.5%
151	Orbital Myositis	7.5%
152	Trachoma	7.4%
153	Diplopia	7.4%
154	Scotoma	7.4%
155	Photophobia	7.4%
156	Amaurosis	7.4%
157	Blindness	7.4%
158	Retinoblastoma	7.4%
159	Sleep Wake Disorders	7.4%
160	Acoustic Neuroma	7.2%
161	Spinal Cord Injuries	7.1%
162	Brain Diseases	7%
163	Dysautonomia	7%
164	Meningitis	7%
165	Movement Disorders	7%
166	Pachymeningitis	7%
167	Spinal Cord Diseases	7%
168	Heavy Metal Poisoning, Nervous System	7%
169	Neuromuscular Junction Diseases	7%
170	Tauopathies	7%
171	Peripheral Nervous System Diseases	7%
172	Peripheral Nerve Injuries	6.9%
173	Lewy Body Disease	6.9%
174	Anophthalmos	6.9%
175	Endophthalmitis	6.9%
176	Microphthalmos	6.9%
177	Pemphigoid, Benign Mucous Membrane	6.9%
178	Retinal Artery Occlusion	6.9%
179	Retinopathy of Prematurity	6.9%
180	Orbital Cellulitis	6.9%
181	Retinal Vasculitis	6.9%
182	Hypertensive Retinopathy	6.9%
183	Retrobulbar Hemorrhage	6.9%
184	Corneal Endothelial Cell Loss	6.9%
185	Guillain-Barre Syndrome	6.9%
186	Striatonigral Degeneration	6.9%
187	Myasthenia Gravis	6.8%
188	Asterixis	6.8%
189	Ballismus	6.8%
190	Hyphema	6.8%
191	Retinal Neovascularization	6.8%
192	Vitreous Hemorrhage	6.8%
193	Acanthamoeba Keratitis	6.8%
194	Angle Closure Glaucoma	6.8%
195	Glaucoma, Open-Angle	6.8%
196	Macular degeneration	6.8%
197	Panuveitis	6.8%
198	Retinal Drusen	6.8%
199	Retinal Necrosis Syndrome, Acute	6.8%
200	Retinoschisis	6.8%
201	Exfoliation Syndrome	6.8%
202	Mobius Syndrome	6.8%
203	Bell Palsy	6.8%
204	Keratitis, Herpetic	6.8%
205	Myelitis	6.8%
206	Progressive bulbar palsy	6.8%
207	Cytomegalovirus Retinitis	6.8%
208	Bulbar palsy	6.8%
209	Herpes Zoster Oticus	6.8%
210	Dandy-Walker Syndrome	6.7%
211	Bacterial conjunctivitis	6.7%
212	Pneumocephalus	6.7%
213	Poliomyelitis	6.7%
214	Causalgia	6.7%
215	Trigeminal Neuralgia	6.2%
216	Leukoencephalitis, Acute Hemorrhagic	6.1%
217	Neuroleptic Malignant Syndrome	6.1%
218	Myelinolysis, Central Pontine	6.1%
219	Epidural Abscess	6.1%
220	MPTP Poisoning	6%
221	Hemianopsia	6%
222	Myelitis, Transverse	6%
223	Chronic Fatigue Syndrome	6%
224	Shy-Drager Syndrome	5.9%
225	Lambert-Eaton Myasthenic Syndrome	5.9%
226	Reflex Sympathetic Dystrophy	5.9%
227	Subdural Effusion	5.9%
228	Parkinsonian Disorders	5.9%
229	Nocturnal Myoclonus Syndrome	5.9%
230	Sleep Disorders, Circadian Rhythm	5.9%
231	Encephalomyelitis, Acute Disseminated	5.8%
232	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	5.8%
233	Botulism	5.6%
234	Central Nervous System Cysts	5.6%
235	Amaurosis Fugax	5.6%
236	Blindness, Cortical	5.6%
237	Anterior uveitis	5.6%
238	Uveitis, Posterior	5.6%
239	Dystonia Musculorum Deformans	5.6%
240	Dyskinesia, Drug-Induced	5.5%
241	Retinal Vein Occlusion	5.5%
242	Central Nervous System Infection	5.5%
243	Myopathy	5.5%
244	Diabetic Retinopathy	5.4%
245	Eye pain	5.4%
246	Panophthalmitis	5.4%
247	Brain Injuries	5.4%
248	Brain Neoplasms	5.4%
249	Multiple Sclerosis	5.4%
250	Spinal Cord Neoplasms	5.4%
251	Craniocerebral Trauma	5.3%
252	Parasomnia	5.3%
253	Dyssomnias	5.3%
254	Decerebrate State	5.2%
255	Hemiparesis	5.2%
256	Hydranencephaly	5.2%
257	Meningism	5.2%
258	Neural Tube Defects	5.2%
259	Paresis	5.2%
260	Seizures	5.2%
261	Sensation Disorders	5.2%
262	Tethered Cord Syndrome	5.2%
263	Central Nervous System Neoplasms	5.2%
264	Complex partial seizures	5.2%
265	Iniencephaly	5.2%
266	Craniorachischisis	5.2%
267	Exencephaly	5.2%
268	Monoparesis	5.2%
269	Septo-Optic Dysplasia	5.2%
270	Cortical Dysplasia	5.2%
271	Neurogenic Inflammation	5.2%
272	Gait Disorders, Neurologic	5.2%
273	Neuromuscular Manifestations	5.2%
274	Malformations of Cortical Development	5.2%
275	Sweating, Gustatory	5.1%
276	Auriculotemporal Syndrome	5.1%
277	Aicardi's syndrome	5.1%
278	Choroidal Neovascularization	5%
279	Meige Syndrome	5%
280	Brachial Plexus Neuritis	5%
281	Neuralgic Amyotrophy	5%
282	Cerebral Ventriculitis	5%
283	Leukoencephalopathy, Progressive Multifocal	5%
284	Epilepsy, Post-Traumatic	4.9%
285	Akathisia, Drug-Induced	4.9%
286	Scrapie	4.8%
287	Central Cord Syndrome	4.8%
288	Limbic Encephalitis	4.7%
289	Presenile dementia	4.7%
290	Senile dementia	4.7%
291	Meningitis, Bacterial	4.7%
292	Meningitis, Fungal	4.7%
293	Chorea	4.7%
294	Acrodynia	4.7%
295	Alstrom Syndrome	4.6%
296	Huntington Disease	4.6%
297	Tarsal Tunnel Syndrome	4.6%
298	Cauda Equina Syndrome	4.6%
299	Posterior Leukoencephalopathy Syndrome	4.6%
300	Posterior reversible encephalopathy syndrome	4.6%
301	Akinetic Mutism	4.5%
302	Anoxic Encephalopathy	4.5%
303	Arachnoiditis	4.5%
304	Basal Ganglia Diseases	4.5%
305	Brain Damage, Chronic	4.5%
306	Cerebellar Diseases	4.5%
307	Encephalitis	4.5%
308	Encephalomalacia	4.5%
309	Epilepsy	4.5%
310	Hydrocephalus	4.5%
311	Congenital Hydrocephalus	4.5%
312	Hypothalamic Diseases	4.5%
313	Aseptic Meningitis	4.5%
314	Neuritis	4.5%
315	Polyneuritis	4.5%
316	Radiculitis	4.5%
317	Syringomyelia	4.5%
318	Thalamic Diseases	4.5%
319	Intracranial Hypertension	4.5%
320	Polyneuropathy	4.5%
321	Mononeuritis	4.5%
322	Aura	4.5%
323	Leukoencephalopathy	4.5%
324	Essential Tremor	4.5%
325	Neuroaxonal Dystrophies	4.5%
326	Familial Tremor	4.5%
327	Headache Disorders	4.5%
328	Mononeuropathies	4.5%
329	Intracranial Hypotension	4.5%
330	Brachial Plexus Neuropathies	4.5%
331	Radiculopathy	4.5%
332	Mononeuropathy Multiplex	4.5%
333	Nerve Root Compression	4.5%
334	Myasthenia Gravis, Autoimmune, Experimental	4.5%
335	Brain Edema	4.5%
336	Brain Hypoxia	4.5%
337	Aqueductal Stenosis	4.5%
338	Pneumorrhachis	4.5%
339	Writer's Cramp	4.5%
340	Lafora Disease	4.5%
341	Unverricht-Lundborg Syndrome	4.5%
342	Brain Abscess	4.5%
343	Charcot-Marie-Tooth Disease	4.5%
344	Lupus Vasculitis, Central Nervous System	4.4%
345	Cerebellar Neoplasms	4.4%
346	Ocular Motility Disorders	4.3%
347	Cyclophoria	4.3%
348	Vasculitis, Central Nervous System	4.3%
349	Jet Lag Syndrome	4.3%
350	Neurobehavioral Manifestations	4.3%
351	Brain Death	4.2%
352	Coma, Post-Head Injury	4.2%
353	Canavan Disease	4.2%
354	Alexander Disease	4.2%
355	Paraneoplastic Encephalomyelitis	4.2%
356	Myoclonic Epilepsy	4.1%
357	Epilepsy, Temporal Lobe	4.1%
358	Ophthalmia Neonatorum	4.1%
359	Epilepsy, Rolandic	4.1%
360	Benign Rolandic Epilepsy	4.1%
361	CHARGE Syndrome	4.1%
362	Sturge-Weber Syndrome	4.1%
363	Vertigo	4.1%
364	Alcohol-Induced Disorders, Nervous System	4.1%
365	Dementia, Vascular	4.1%
366	Brain Hemorrhage, Traumatic	4.1%
367	Herpes Zoster Ophthalmicus	4.1%
368	Tuberous Sclerosis	4%
369	Friedreich Ataxia	4%
370	Creutzfeldt-Jakob disease	4%
371	Basal Ganglia Cerebrovascular Disease	4%
372	Brain Injuries, Diffuse	4%
373	Traumatic Brain Injury	4%
374	Cerebellar Ataxia	4%
375	Supratentorial Neoplasms	4%
376	Torticollis	4%
377	Multiple Sclerosis, Chronic Progressive	4%
378	Multiple Sclerosis, Relapsing-Remitting	4%
379	Ataxia Telangiectasia	4%
380	Myotonia Congenita	3.9%
381	Paraneoplastic Cerebellar Degeneration	3.9%
382	Cerebrospinal Fluid Otorrhea	3.9%
383	Cerebrospinal Fluid Rhinorrhea	3.9%
384	Neuritis, Autoimmune, Experimental	3.9%
385	Gait Ataxia	3.9%
386	Tuberculosis, Meningeal	3.7%
387	Carotid Artery Injuries	3.7%
388	Juvenile Myoclonic Epilepsy	3.7%
389	Myoclonic Epilepsies, Progressive	3.7%
390	Carpal Tunnel Syndrome	3.7%
391	Vascular Headaches	3.7%
392	neurofibroma	3.6%
393	Hypoxia-Ischemia, Brain	3.6%
394	Sciatica	3.6%
395	Tardive Dyskinesia	3.6%
396	Persistent Vegetative State	3.6%
397	Myotonic Dystrophy	3.5%
398	Voice Disorders	3.5%
399	Voice Disturbance	3.5%
400	Brain Diseases, Metabolic	3.4%
401	Cerebrovascular Disorders	3.4%
402	Myositis	3.4%
403	Cerebrovascular Insufficiency	3.4%
404	Isaacs syndrome	3.4%
405	Arsenic Poisoning	3.4%
406	Dementia	3.4%
407	Myotonic Disorders	3.4%
408	Central Nervous System Fungal Infections	3.4%
409	Conus Medullaris Syndrome	3.4%
410	Myasthenic Syndromes, Congenital	3.4%
411	Spinal Cord Vascular Diseases	3.4%
412	Hepatolenticular Degeneration	3.4%
413	Graves Disease	3.4%
414	Smith-Magenis syndrome	3.4%
415	Diabetic Neuropathies	3.4%
416	Facial Injuries	3.4%
417	Diabetic Amyotrophy	3.4%
418	Diabetic Autonomic Neuropathy	3.4%
419	Sleep Talking	3.4%
420	Manganese Poisoning	3.4%
421	Dural Arteriovenous Fistula	3.4%
422	Sleep Disorders, Intrinsic	3.4%
423	Orthostatic intolerance	3.4%
424	Cerebral Palsy	3.4%
425	Epilepsies, Partial	3.4%
426	Epilepsy, Generalized	3.4%
427	Pseudotumor Cerebri	3.4%
428	Sciatic Neuropathy	3.4%
429	Hypertensive Encephalopathy	3.4%
430	Ulnar Neuropathies	3.4%
431	Lesion of Sciatic Nerve	3.4%
432	Simple Partial Seizures	3.4%
433	Epilepsy, Reflex	3.4%
434	Ulnar Neuritis	3.4%
435	Radial nerve compression	3.4%
436	Radial Tunnel Syndrome	3.4%
437	Peroneal Neuropathies	3.4%
438	Radial Neuropathy	3.4%
439	Median Neuropathy	3.4%
440	Sciatic Nerve Palsy	3.4%
441	Femoral Neuropathy	3.4%
442	Tibial Neuropathy	3.4%
443	Ulnar Nerve Palsy	3.4%
444	Alice in Wonderland Syndrome	3.4%
445	Postural Orthostatic Tachycardia Syndrome	3.4%
446	Radial nerve palsy	3.4%
447	Headache Disorders, Primary	3.4%
448	Headache Disorders, Secondary	3.4%
449	Medication overuse headache	3.4%
450	Anosmia	3.4%
451	Ataxia	3.4%
452	Athetosis	3.4%
453	Catalepsy	3.4%
454	Dystonia	3.4%
455	Hemiplegia	3.4%
456	Locked-In Syndrome	3.4%
457	Meningeal Neoplasms	3.4%
458	Meningomyelocele	3.4%
459	Muscle Hypertonia	3.4%
460	Muscle hypotonia	3.4%
461	Myoclonus	3.4%
462	Myotonia	3.4%
463	Neuralgia	3.4%
464	Paraplegia	3.4%
465	Pseudobulbar Palsy	3.4%
466	Quadriplegia	3.4%
467	Spasm	3.4%
468	Spastic Paraplegia	3.4%
469	Status Epilepticus	3.4%
470	Taste Disorders	3.4%
471	Tremor	3.4%
472	Spina Bifida	3.4%
473	Monoplegia	3.4%
474	Hypokinesia	3.4%
475	Paraparesis	3.4%
476	Bradykinesia	3.4%
477	Waxy flexibility	3.4%
478	Action Tremor	3.4%
479	Resting Tremor	3.4%
480	Dysosmia	3.4%
481	Quadriparesis	3.4%
482	Mercury Poisoning, Nervous System	3.4%
483	Olfaction Disorders	3.4%
484	Myokymia	3.4%
485	Lead Poisoning, Nervous System	3.4%
486	Somatosensory Disorders	3.4%
487	Neuropathic pain	3.4%
488	Hyperkinesia	3.4%
489	Intention tremor	3.4%
490	Leukomalacia, Periventricular	3.3%
491	Alcohol Withdrawal Seizures	3.3%
492	Akathisia	3.3%
493	Restlessness	3.3%
494	Psychomotor Agitation	3.3%
495	Mandibulofacial Dysostosis	3.3%
496	Cubital Tunnel Syndrome	3.3%
497	Diffuse Axonal Injury	3.3%
498	Brain Stem Neoplasms	3.3%
499	Brain Concussion	3.3%
500	Pituitary Adenoma	3.1%
501	Pituitary Neoplasms	3.1%
502	Toxoplasmosis, Cerebral	3.1%
503	Vertebral Artery Dissection	3.1%
504	Amnesia, Transient Global	3.1%
505	Gait Apraxia	3%
506	Meningitis, Cryptococcal	3%
507	Meningitis, Listeria	3%
508	Refsum Disease	3%
509	Meningitis, Haemophilus	3%
510	Meningitis, Pneumococcal	3%
511	Frontotemporal dementia	3%
512	Albinism	3%
513	Basal Ganglia Hemorrhage	2.9%
514	Choroid Plexus Papilloma	2.9%
515	Reflex, Abnormal	2.9%
516	Hyporeflexia	2.9%
517	Hyperreflexia	2.9%
518	Hand-Arm Vibration Syndrome	2.9%
519	Mitochondrial Encephalomyopathies	2.8%
520	Polyradiculopathy	2.8%
521	Post-Traumatic Headache	2.8%
522	Tension Headache	2.8%
523	Epilepsy, Complex Partial	2.8%
524	Migraine Disorders	2.8%
525	Abdominal Migraine	2.8%
526	Status Migrainosus	2.8%
527	Cervicogenic Headache	2.8%
528	Fibromyalgia	2.8%
529	Pituitary Apoplexy	2.8%
530	Central Nervous System Bacterial Infections	2.8%
531	Medial Tibial Stress Syndrome	2.8%
532	Brain Contusion	2.7%
533	Mitochondrial Myopathies	2.7%
534	Brain Infarction	2.7%
535	Confusion	2.7%
536	Facial paralysis	2.7%
537	Lethargy	2.7%
538	Memory Disorders	2.7%
539	Muscle Cramp	2.7%
540	Perceptual Disorders	2.7%
541	Psychomotor Disorders	2.7%
542	Eosinophilia-Myalgia Syndrome	2.7%
543	Anhedonia	2.7%
544	Disorientation	2.7%
545	Facial Paresis	2.7%
546	Memory Loss	2.7%
547	Hemisensory Neglect	2.7%
548	Dysacusis	2.7%
549	Subarachnoid Hemorrhage, Traumatic	2.7%
550	Sleep Bruxism	2.7%
551	Carotid Artery, Internal, Dissection	2.7%
552	Anencephaly	2.7%
553	Meningocele	2.7%
554	Muscular Atrophy	2.7%
555	Respiratory Paralysis	2.7%
556	Encephalocele	2.7%
557	Subacute Sclerosing Panencephalitis	2.7%
558	Putaminal Hemorrhage	2.7%
559	Tetany	2.7%
560	Pituitary Diseases	2.7%
561	Infarction, Middle Cerebral Artery	2.6%
562	Infarction, Anterior Cerebral Artery	2.6%
563	Infarction, Posterior Cerebral Artery	2.6%
564	Thoracic Outlet Syndrome	2.6%
565	Classical Lissencephalies and Subcortical Band Heterotopias	2.6%
566	Amyloid Neuropathies, Familial	2.6%
567	Carotid Artery Diseases	2.5%
568	Brain Ischemia	2.5%
569	Hypotension, Orthostatic	2.5%
570	Sleep Apnea Syndromes	2.5%
571	Cerebrovascular accident	2.5%
572	Polymyositis	2.5%
573	Kluver-Bucy Syndrome	2.5%
574	Vasospasm, Intracranial	2.5%
575	Spinal Cord Ischemia	2.5%
576	Intracranial Arterial Diseases	2.5%
577	Post-Exercise Hypotension	2.5%
578	Cluster Headache	2.5%
579	Migraine with Aura	2.5%
580	Familial Hemiplegic Migraine	2.5%
581	Chronic Paroxysmal Hemicrania	2.5%
582	SUNCT Syndrome	2.5%
583	Paroxysmal Hemicrania	2.5%
584	Disorders of Excessive Somnolence	2.5%
585	Sleep Initiation and Maintenance Disorders	2.5%
586	Night Terrors	2.5%
587	Somnambulism	2.5%
588	Transient Insomnia	2.5%
589	Sleep Paralysis	2.5%
590	Chronic Insomnia	2.5%
591	REM Sleep Behavior Disorder	2.5%
592	Hypersomnia	2.5%
593	Dermal Sinus	2.5%
594	Dysgeusia	2.5%
595	Formication	2.5%
596	Hyperalgesia	2.5%
597	Hyperesthesia	2.5%
598	Hypesthesia	2.5%
599	Language Disorders	2.5%
600	Numbness	2.5%
601	Paresthesia	2.5%
602	Paraparesis, Spastic	2.5%
603	Spina Bifida Cystica	2.5%
604	Trismus	2.5%
605	Spina Bifida Occulta	2.5%
606	Epilepsia Partialis Continua	2.5%
607	Sicca Syndrome	2.5%
608	Hypogeusia	2.5%
609	Meningeal Carcinomatosis	2.5%
610	Brown-Sequard Syndrome	2.5%
611	Lissencephaly	2.5%
612	Polymicrogyria	2.5%
613	Pachygyria	2.5%
614	Schizencephaly	2.5%
615	Lockjaw	2.5%
616	Allodynia	2.5%
617	Lead Poisoning, Nervous System, Childhood	2.5%
618	Lead Poisoning, Nervous System, Adult	2.5%
619	Sjogren's Syndrome	2.5%
620	Periventricular Nodular Heterotopia	2.5%
621	Ageusia	2.5%
622	Tuberculosis, Central Nervous System	2.5%
623	Auditory Perceptual Disorders	2.5%
624	Adrenoleukodystrophy	2.5%
625	Cerebral Infarction	2.4%
626	Brain Stem Infarctions	2.4%
627	Giant Cell Arteritis	2.4%
628	Temporal Arteritis	2.4%
629	Alexia	2.3%
630	Dyslexia	2.3%
631	Lateral Medullary Syndrome	2.3%
632	Consciousness Disorders	2.3%
633	Mental Retardation	2.3%
634	Muscle Weakness	2.3%
635	Depressed Level of Consciousness	2.3%
636	Mental deficiency	2.3%
637	Intellectual Disability	2.3%
638	Catatonia	2.3%
639	Familial Periodic Paralysis	2.2%
640	Aphonia	2.2%
641	Sleep Deprivation	2.2%
642	Dysphonia	2.2%
643	Moyamoya Disease	2.2%
644	MELAS Syndrome	2.2%
645	Neurofibrosarcoma	2.2%
646	West Nile Fever	2.2%
647	Hematoma, Subdural	2.1%
648	Hematoma, Epidural, Cranial	2.1%
649	Empty Sella Syndrome	2.1%
650	Hyperpituitarism	2.1%
651	Hypopituitarism	2.1%
652	Hypophysitis	2.1%
653	Cerebral Arterial Diseases	2.1%
654	Vertebrobasilar Insufficiency	2.1%
655	Anterior Spinal Artery Syndrome	2.1%
656	Basilar Artery Stenosis	2.1%
657	Vertebral Artery Stenosis	2.1%
658	Sleep Apnea, Obstructive	2.1%
659	Sleep Apnea, Central	2.1%
660	Intracranial Hemorrhage, Hypertensive	2.1%
661	Transient Cerebral Ischemia	2.1%
662	Narcolepsy	2.1%
663	Kleine-Levin Syndrome	2.1%
664	Agraphia	2.1%
665	Anomia	2.1%
666	Cluttering	2.1%
667	Language Development Disorders	2.1%
668	Speech Disorders	2.1%
669	Syncope	2.1%
670	Stupor	2.1%
671	Dysgraphia	2.1%
672	Presyncope	2.1%
673	Dyslalia	2.1%
674	Muscular Dystrophy	2%
675	Muscle Rigidity	2%
676	Muscle Spasticity	2%
677	Cogwheel Rigidity	2%
678	Hemifacial Spasm	2%
679	Nuchal Rigidity	2%
680	Reye Syndrome	2%
681	Neuroaspergillosis	2%
682	Pyomyositis	2%
683	Intracranial Embolism and Thrombosis	2%
684	Hepatic Encephalopathy	2%
685	Agnosia	2%
686	Apraxias	2%
687	Hallucinations	2%
688	Hyperacusis	2%
689	Tinnitus	2%
690	Visual Agnosia	2%
691	Anosognosia	2%
692	Wernicke-Korsakoff Syndrome	2%
693	Phonophobia	2%
694	Hearing Loss	2%
695	Sarcopenia	2%
696	Myalgia	1.9%
697	Behcet Syndrome	1.9%
698	Neuronal Ceroid-Lipofuscinoses	1.9%
699	Hyperprolactinemia	1.9%
700	Hematoma, Subdural, Intracranial	1.9%
701	Hematoma, Subdural, Chronic	1.9%
702	Hematoma, Subdural, Acute	1.9%
703	Subclavian Steal Syndrome	1.9%
704	Pick Disease of the Brain	1.9%
705	Cataplexy	1.9%
706	Aphasia	1.8%
707	Articulation Disorders	1.8%
708	Echolalia	1.8%
709	Stuttering	1.8%
710	Dysphasia	1.8%
711	Pseudorabies	1.8%
712	Dysarthria	1.7%
713	Hoarseness	1.7%
714	Toxoplasmosis, Congenital	1.7%
715	Amnesia	1.7%
716	Delirium	1.7%
717	Dissociative Amnesia	1.7%
718	Global Amnesia	1.7%
719	Eye Burns	1.7%
720	Cri-du-Chat Syndrome	1.7%
721	Down Syndrome	1.7%
722	Brain Diseases, Metabolic, Inborn	1.7%
723	Trisomy 21	1.7%
724	Cockayne Syndrome	1.7%
725	Malaria, Cerebral	1.7%
726	POEMS Syndrome	1.7%
727	Alcohol Withdrawal Delirium	1.7%
728	Meningioma	1.7%
729	Williams Syndrome	1.7%
730	Carotid Stenosis	1.7%
731	Intracranial Aneurysm	1.7%
732	Welander Distal Myopathy	1.7%
733	Neurocysticercosis	1.7%
734	Microcephaly	1.7%
735	Macrocephaly	1.7%
736	Dyscalculia	1.7%
737	Intracranial Arteriosclerosis	1.7%
738	Cerebral Atherosclerosis	1.7%
739	Rett Syndrome	1.7%
740	Subarachnoid Hemorrhage	1.7%
741	Cerebral Arteriosclerosis	1.7%
742	Cerebral Hemorrhage	1.7%
743	Neurosyphilis	1.6%
744	Hypokalemic periodic paralysis	1.6%
745	Cerebral Thrombosis	1.6%
746	Intracranial Embolism	1.6%
747	Intracranial Thrombosis	1.6%
748	Deafness	1.6%
749	Hearing Loss, Sudden	1.6%
750	Gerstmann Syndrome	1.6%
751	Hearing Loss, Bilateral	1.6%
752	Hearing Loss, High-Frequency	1.6%
753	Hearing Loss, Mixed Conductive-Sensorineural	1.6%
754	Prosopagnosia	1.6%
755	Apraxia, Ideomotor	1.6%
756	Charles Bonnet Syndrome	1.6%
757	Hearing Loss, Unilateral	1.6%
758	Complete Hearing Loss	1.6%
759	Alien Hand Syndrome	1.6%
760	Deaf Mutism	1.6%
761	Porencephaly	1.6%
762	Mutism	1.5%
763	Selective Mutism	1.5%
764	Acromegaly	1.5%
765	Holoprosencephaly	1.5%
766	Cerebral Amyloid Angiopathy	1.5%
767	Sinus Thrombosis, Intracranial	1.5%
768	Prader-Willi Syndrome	1.4%
769	Wernicke Encephalopathy	1.4%
770	AIDS Dementia Complex	1.4%
771	Dermatomyositis	1.4%
772	Phantom pain	1.4%
773	Phantom Limb Pain	1.4%
774	Waterhouse-Friderichsen Syndrome	1.4%
775	Lyme Neuroborreliosis	1.4%
776	Alexia, Pure	1.4%
777	Muscular Dystrophy, Duchenne	1.4%
778	Cavernous Sinus Thrombosis	1.4%
779	Sagittal Sinus Thrombosis	1.4%
780	Retrograde amnesia	1.4%
781	Amnesia, Anterograde	1.4%
782	Carotid Artery Thrombosis	1.4%
783	Menkes Kinky Hair Syndrome	1.4%
784	Kernicterus	1.3%
785	Fragile X Syndrome	1.2%
786	Nelson Syndrome	1.2%
787	Rubinstein-Taybi Syndrome	1.1%
788	Prolactinoma	1.1%
789	Growth Hormone-Secreting Pituitary Adenoma	1.1%
790	Fabry Disease	1.1%
791	Galactosemias	1%
792	Urea Cycle Disorders, Inborn	1%
793	Tyrosinemias	1%
794	Homocystinuria	0.9%
795	Leigh Disease	0.9%
796	Carbamoyl-Phosphate Synthase I Deficiency Disease	0.8%
797	Mucopolysaccharidosis II	0.8%
798	Glycogen storage disease type II	0.7%
799	Zellweger Syndrome	0.7%
800	Gaucher Disease	0.6%
801	Tay-Sachs Disease	0.6%
802	Niemann-Pick Disease, Type C	0.5%

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